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This document is an editorial published in the journal Frontiers in Cellular & Infection Microbiology. The editorial discusses the use of stem cell technologies in the study of tropical infectious diseases. The authors highlight the challenges in studying these diseases and the potential of stem cell technologies to overcome these challenges. They provide examples of how stem cell technologies have been applied to the study of malaria and Chagas disease, and they discuss the potential of these technologies in studying other parasites such as Toxoplasma gondii and helminths. The authors emphasize the importance of stem cell-based approaches in understanding and finding new avenues for prevention and treatment of these diseases. [Extracted from the article]