1. What are the situational and behavioral factors associated with condomless anal sex without pre-exposure prophylaxis in MSM ?
- Author
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Di Ciaccio, M., Sagaon Teyssier, Luis, Mimi, M., Suzan-Monti, M., Protiere, C., Castro, D. R., Meyer, L., Tremblay, C., Chidiac, C., Capitant, C., Preau, M., Molina, J. M., Spire, B., and ANRS IPERGAY Study Group
- Subjects
on-demand pre-exposure prophylaxis ,ANRS-IPERGAY ,MSM ,unprotected anal intercourse ,condom - Abstract
Objective: This study aimed to identify situational and behavioral factors associated with condomless anal sex without on-demand PrEP in the open-label extension (OLE) study of the ANRS-IPERGAY trial. Methods: Univariable and multivariable modified Poisson regressions with a generalized estimating equation (GEE) were used. The attributable risk percentage for each explanatory variable and for condomless anal sex without PrEP was calculated. Results: In the OLE, 19% of anal intercourses were unprotected (i.e. no PrEP or condom). Of these, 85% were attributable to sexual intercourse with main partners and 47% with HIV-negative partners. The following factors were positively associated with condomless anal sex without PrEP: a depressive episode in the previous 12 months [aR (95% CI),P-value: 1.49 (1.02--2.17), 0.039], a higher number of sexual intercourses during the previous 4 weeks [1.01 [1.002--1.02], 0.014], and sexual intercourses under the influence of alcohol [1.45 (1.10--1.92), 0.008]. By contrast, condomless anal sex without PrEP was less frequent during sexual intercourses with known casual, unknown casual and multiple partners [0.20 (0.14--0.30)
- Published
- 2020