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This paper presents the evaluation of the use of insecticides in the agricultural production of the Kursk region. Studied territorial load dominant crop insecticides in a complex region for the period 2006-2013, were ranked the region in terms of territorial load insecticides. Estimated figures on theenvironmental risk of the formation of the pathology of the gastrointestinal tract of the adult population of the Kursk region in the intensive use of insecticides. Environmentally sensitive identified pathologies such as gastric ulcer and duodenal ulcers, gastritis and duodenitis, functional bowel disorders, diseases of the pancreas.