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Monkeypox is a zoonotic disease. Since the first human monkeypox case was detected in 1970, it has been prevalent in some countries in central and western Africa. Since May 2022, monkeypox cases have been reported in more than 96 non-endemic countries and regions worldwide. As of September 14, 2022, there have been more than 58,200 human monkeypox cases, and there is community transmission. The cessation of smallpox vaccination in 1980, which had some cross-protection with monkeypox, resulted in a general lack of immunity to monkeypox, which caused global concern and vigilance. As of September 14, 2022, there are four monkeypox cases in China, including three in Taiwan province and one in Hong Kong city. Previous foreign studies have shown that children are vulnerable to monkeypox and are also at high risk for severe disease or complications. In order to improve pediatricians' understanding of monkeypox and achieve early detection, early diagnosis, early treatment, and early disposal, we have organized national authoritative experts in pediatric infection, respiratory, dermatology, critical care medicine, infectious diseases, and public health and others to formulate this expert consensus, on the basis of the latest "Clinical management and infection prevention and control for monkeypox" released by The World Health Organization, the "guidelines for diagnosis and treatment of monkeypox (version 2022)" issued by National Health Commission of the People's Republic of China and other relevant documents. During the development of this consensus, multidisciplinary experts have repeatedly demonstrated the etiology, epidemiology, transmission, clinical manifestations, laboratory examinations, diagnosis, differential diagnosis, treatment, discharge criteria, prevention, disposal process, and key points of prevention and control of suspected and confirmed cases.

The distribution of spatial variations in soil heavy metal is an important factor upon assessment of soil heavy metal. Reasonable sampling intervals and element attribute value evaluation can improve the accuracy of the evaluation models. Different heavy metal elements have different characteristics in spatial distribution. In this paper spatial variability and structure analysis of statistical technology were applied to the agricultural test plots which consist of cinnamon soil in Binzhou, Shandong. Optimal selection about the model was performed by kriging interpolation method. Then, the reasonable sampling spacing could be determinate well. In this research, by means of the sample testing results on five elements of heavy metals: Pb, Cd, Hg, Cu, Cr, which could reflect the levels of the soil pollution, aforementioned geo-statistical analysis process was done. In the sampling densities among them, chromium was the minimum; Mercury and cadmium were the largest, the rest of the middle. The results indicated that, the Spherical Model was more suitable for fitting description of soil heavy metal space distribution. Soil heavy metal variations were a result of comprehensive external effect of topography and land use, also the effects exhibit different at various scales. Due to pollution source, tillage form and other factors, choosing different sampling spacing for different heavy metal elements were more reasonable.