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Your search keyword '"neutrophil‐related chemokines"' showing total 3 results
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3 results on '"neutrophil‐related chemokines"'

1. The CSF Levels of Neutrophil‐Related Chemokines in Patients with Neuromyelitis Optica

Author

Zhuhe Liu, Jinyu Chen, Zhanhang Wang, Yao Wang, Dong Zheng, Honghao Wang, and Yu Peng

Subjects
neutrophil‐related chemokines, CXCL1, CXCL5, CXCL7, neuromyelitis optica, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract Pathologic findings showed that neutrophils played an important role in the pathogenesis of NMO. This study aims to investigate the CSF levels of neutrophil‐related chemokines in NMO. CXCL1, CXCL5, and CXCL7 were measured in 95 patients with NMO, 15 patients with MS, 18 patients with GFAP astrocytopathy, and 16 controls. The CSF level of CXCL1, CXCL5, and CXCL7 was significantly elevated in the NMO group but not correlated with the patient clinical severity. Besides, the CSF CXCL1, CXCL5, and CXCL7 could act as biomarkers to distinguish NMO from MS with good reliability, especially the CXCL7.

Published
2020
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2. The CSF Levels of Neutrophil‐Related Chemokines in Patients with Neuromyelitis Optica.

Author

Liu, Zhuhe, Chen, Jinyu, Wang, Zhanhang, Wang, Yao, Zheng, Dong, Wang, Honghao, and Peng, Yu

Subjects
*NEUROMYELITIS optica, *CHEMOKINES, *PATHOLOGY
Abstract

Pathologic findings showed that neutrophils played an important role in the pathogenesis of NMO. This study aims to investigate the CSF levels of neutrophil‐related chemokines in NMO. CXCL1, CXCL5, and CXCL7 were measured in 95 patients with NMO, 15 patients with MS, 18 patients with GFAP astrocytopathy, and 16 controls. The CSF level of CXCL1, CXCL5, and CXCL7 was significantly elevated in the NMO group but not correlated with the patient clinical severity. Besides, the CSF CXCL1, CXCL5, and CXCL7 could act as biomarkers to distinguish NMO from MS with good reliability, especially the CXCL7. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
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3. The CSF Levels of Neutrophil‐Related Chemokines in Patients with Neuromyelitis Optica

Author

Yao Wang, Jinyu Chen, Honghao Wang, Yu Peng, Dong Zheng, Zhanhang Wang, and Zhuhe Liu

Subjects
0301 basic medicine, Adult, Male, Chemokine, Chemokine CXCL5, animal diseases, Chemokine CXCL1, Neurosciences. Biological psychiatry. Neuropsychiatry, Brief Communication, Severity of Illness Index, Neutrophil Activation, Pathogenesis, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Clinical severity, In patient, RC346-429, Neuromyelitis optica, biology, business.industry, General Neuroscience, Neuromyelitis Optica, CXCL5, respiratory system, Middle Aged, medicine.disease, beta-Thromboglobulin, CXCL1, 030104 developmental biology, CXCL7, Immunology, biology.protein, neutrophil‐related chemokines, Female, Neurology (clinical), Neurology. Diseases of the nervous system, business, Brief Communications, 030217 neurology & neurosurgery, RC321-571
Abstract

Pathologic findings showed that neutrophils played an important role in the pathogenesis of NMO. This study aims to investigate the CSF levels of neutrophil‐related chemokines in NMO. CXCL1, CXCL5, and CXCL7 were measured in 95 patients with NMO, 15 patients with MS, 18 patients with GFAP astrocytopathy, and 16 controls. The CSF level of CXCL1, CXCL5, and CXCL7 was significantly elevated in the NMO group but not correlated with the patient clinical severity. Besides, the CSF CXCL1, CXCL5, and CXCL7 could act as biomarkers to distinguish NMO from MS with good reliability, especially the CXCL7.

Published
2020

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