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Copyright of Aydin Dental Journal is the property of Aydin Dental Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Osmangazi Journal of Medicine / Osmangazi Tip Dergisi is the property of Eskisehir Osmangazi University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Trauma & Emergency Surgery / Ulusal Travma ve Acil Cerrahi Dergisi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives:Frozen Section (Fs) Is Mainly Performed To Decide If The Sampled Tissue In Surgery Is Benign Or Malignant. The Accuracy Of Fs Exams Varies Based On The Specific Anatomical Site. False Diagnoses May Cause Consequences For Surgeons And Patients, Considering The Circumstances Of False Positive Reports. In This Study, We Aimed To Evaluate The Accuracy Of This Method (Frozen Biopsy) In Surgeries. Materials and Methods:In This Retrospective Study, Frozen Sections Of The Pathology Department Of Taleghani Hospital Have Been Reviewed And Compared With The Permanent Section Results As Gold Standard To Evaluate The Sensitivity And Specificity Of The Test. In Cases Where The Results Were Dissonant, We Investigated The Causes Of This Discordance. Results:A Total Of 1016 Samples From 557 Patients Were Studied. The Mean Age Of The Patients Was 52.15 ± 16.94. In The Study Of Frozen Sections, 778 Sections (76.6%) Were Benign, 192 Sections (18.9%) Were Malignant, 38 Sections (3.7%) Were Suspected, And In 8 Sections (0.8%) The Samples Could Not Be Identified Due To The Inappropriate Specimen. In All, 95 Cases (9.35%) Were Deferred, And Of The Remaining, 19 Cases (2.06%) Were Discordant. Out Of 19 Discordant Cases, 13 Cases (68.4%) Were Due To Pathologist Interpretation Error. Sensitivity, Specificity, Positive Predictive Value, And Negative Predictive Value Of All Samples Were 93.37%, 99.32%, 97.13%, And 98.38%, respectively. Conclusion:Frozen section is a valid test for intra-operative consultation and ongoing monitoring in pathology departments should be performed to improve FS accuracy. [ABSTRACT FROM AUTHOR]

Aim: Although most defects can close by primary suturing after radical surgery of gynecological malignancies, different reconstruction options are available when large defects that require reconstruction occur. In this study, we present the treatment strategy and results for patients who underwent reconstruction after resection for gynecological cancer in the vulva and perineum. Material and Methods: A total of 18 patients who underwent reconstruction between May 2018 and July 2020 were included in this retrospective study. Demographics and clinical data, the resection operation, characteristics of the defect, and the reconstruction methods applied were evaluated. Postoperative treatment strategy and complication rates were evaluated. Results: The mean age was 62.3±13.2 (42-83) years. 88.9% of the patients had additional diseases. Pelvic exentration was performed in 5 (27.8%) patients, anterior resection in 2 (11.1%) patients and vulvectomy in 11 (61.1%) patients. The most common malignancy was squamous cell carcinoma, and mean defect size was 106±97 (12-476) cm2. Reconstruction was performed with a local fasciocutaneous flap in 16 (88.9%) patients, pedicled rectus myocutaneous flap in one (5.6%) patient, and skin graft in one (5.6%) patient. Wound complications occurred in 5 (27.8%) patients, partial flap necrosis in one (5.6%) patient, and recurrence in one (5.6%) patient in the long term. Conclusion: It is possible to reconstruction most of the vulva and perineal defects with local flaps after oncological resections, Considering the characteristics of the area and patient comorbidities, it should be kept in mind that prolonged wound problems may be seen, especially in vulvectomy patients.

Copyright of Hamidiye Medical Journal is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkiye Klinikleri Journal of Dental Sciences is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aim: Although most defects can close by primary suturing after radical surgery of gynecological malignancies, different reconstruction options are available when large defects that require reconstruction occur. In this study, we present the treatment strategy and results for patients who underwent reconstruction after resection for gynecological cancer in the vulva and perineum. Material and Methods: A total of 18 patients who underwent reconstruction between May 2018 and July 2020 were included in this retrospective study. Demographics and clinical data, the resection operation, characteristics of the defect, and the reconstruction methods applied were evaluated. Postoperative treatment strategy and complication rates were evaluated. Results: The mean age was 62.3±13.2 (42-83) years. 88.9% of the patients had additional diseases. Pelvic exentration was performed in 5 (27.8%) patients, anterior resection in 2 (11.1%) patients and vulvectomy in 11 (61.1%) patients. The most common malignancy was squamous cell carcinoma, and mean defect size was 106±97 (12-476) cm2. Reconstruction was performed with a local fasciocutaneous flap in 16 (88.9%) patients, pedicled rectus myocutaneous flap in one (5.6%) patient, and skin graft in one (5.6%) patient. Wound complications occurred in 5 (27.8%) patients, partial flap necrosis in one (5.6%) patient, and recurrence in one (5.6%) patient in the long term. Conclusion: It is possible to reconstruction most of the vulva and perineal defects with local flaps after oncological resections, Considering the characteristics of the area and patient comorbidities, it should be kept in mind that prolonged wound problems may be seen, especially in vulvectomy patients. [ABSTRACT FROM AUTHOR]

Objective: This study investigated the effectivity of Magnetic Resonance Imaging (MRI) findings and Apparent Diffusion Coefficient (ADC) value in evaluating parotid gland tumors (PGTs), and aimed to reduce the biopsy procedure before surgery. Methods: This retrospective study included 54 PGTs of 42 patients' (24 female, 18 male, mean age; 51.4±15.9). All of the patients had an MRI, and histopathologic diagnosis. The signal intensity [T1 and T2 Weighted (W), T1W after intravenous contrast agent injection] and mean ADC values of the PGTs were measured. Also contrast enhancement pattern (homogenous, heterogeneous, peripheral or none), margin features (well or ill-defined), sizes, location (superficial lobe/deeplobe/both), perineural spread, presence of lymphadenopathy, and extension to adjacent structures were noted. Results: The distribution of PGTs was; 21 pleomorphic adenomas, 18 Warthin tumors, 2 lymph nodes, 2 mucoepidermoid carcinomas, 5 adenoid cystic carcinoma, 1 basal cell carcinoma, 2 metastases and 2 lymphomas; (13 malignant and 41 benign lesions). Morphologic parameters; ill-defined margin, perineural spread, lymphadenopathy, and extension to adjacent structures were found to be significantly associated with malign lesions (p<0.01). There was a significant difference between ADC values of malignant and benign PGTs (p<0.05). Also ADC values and T2 signal intensity was significantly lower in Warthin tumors rather than pleomorphic adenomas (p<0.05). Conclusions: Mean ADC values when considered with morphological features may be accessible methods to distinguish benign and malignant PGTs, also ADC values and T2 signal intensity may be useful for differentiating pleomorphic adenomas from Warthin tumors, thereby reducing the number of biopsies and thus complications. [ABSTRACT FROM AUTHOR]

Introduction: Insulinoma is the most common functional neuroendocrine tumor of the pancreas. There are different methods for the preoperative localization of insulinoma, such as Computed Tomography (CT) scan, Magnetic Resonance Imaging and Endoscopic Ultra Sonography (EUS). In this study, we report on the clinicopathological features of insulinoma in 43 patients. Methods: The hospital records of 43 patients with suspicion of insulinoma based on biochemical diagnostic criteria, referred to İmam Khomeini Complex Hospital, Tehran, Iran between 2006 and 2016, were reviewed retrospectively. Results: Of the 43 studied patients, 28 were female. The mean age of the patients was 45.4±13.3 years. The most frequent clinical presentation of insulinoma was neurogenic and neuroglycopenic symptoms (81.4%). Mean glucose, insulin, and C-peptide in patients with hypoglycemic crisis were 39.13±13.15 mg/dL, 32.15±32.53 μUI/mL, and 4.77±2.88 ng/mL, respectively. Mean tumor size was 2.13±1.22 cm. The most common site of insulinoma was the tail of the pancreas. Surgery was the treatment of choice and performed in 31 patients. Of 21 tumors studied microscopically, 7 were invasive. Conclusion: In non-diabetic patients with manifestations of hypoglycemia, a diagnosis of insulinoma should be considered. During the past decade, the diagnostic delay for insulinoma has been reduced in our country by improving imaging technologies. EUS and CT scan are the best modalities for localization and size measurement of insulinoma. Tumor size has decreased compared with previous decades, probably due to a reduced delay in diagnosis. [ABSTRACT FROM AUTHOR]

Objective: Pancreatic tumors in children are exceedingly rare and hence present diagnostic and therapeutic challenges to pediatric surgeons. In this study, we aimed to present our experiences and treatment outcomes related to these rare tumors. Methods: The clinical data, laboratory investigations, radiological imaging, and the pathology and surgical details of patients with pancreatic tumors who were diagnosed between 2005 and 2019 were retrospectively reviewed. Results: A total of 9 patients (5 men) were included in the study. The most common symptom at the time of presentation was vague abdominal pain. A pancreatic tumor was detected incidentally in 4 patients. All tumors were non-functional primary tumors. Histopathological diagnosis of these tumors were solidpseudopapillary tumors (n=3), congenital pancreatic cysts (n=3), pancreatoblastoma (n=1), rhabdomyosarcoma (n=1), and an undifferentiated carcinoma (n=1). In addition, 8 patients were treated surgically (through tumor excision, central pancreatectomy + distal pancreaticojejunostomy, distal pancreatectomy, and cystogastrostomy). Two deaths from tumor dissemination were recorded. The patients were followed-up at a mean duration of 72 months (range: 6-120 months). Conclusion: Pediatric pancreatic tumors are rare and are usually benign in nature. They present symptoms that are often nonspecific. In non-metastatic cases, surgical tumor removal is the preferred method for the treatment. For most tumors, surgical resection is the optimal treatment that may be successfully performed with low morbidity rate when the lesion is either in the body or in the tail of the pancreas. The long-term outcomes with this approach are generally good. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Health Sciences of Kocaeli University / Kocaeli Üniversitesi Sağlık Bilimleri Dergisi is the property of Institute of Health Sciences of Kocaeli University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Cancer, one of the biggest reasons of the deaths both in the World and in Turkey, is a long-term disease in which the patients care continues not only in the hospital but also at home and the family members who care for the patient as well as the patient are adversely affected. As well as the affected life of the person suffering from the disease, the lives of the people who provide care are affected physically, emotionally, socially and economically. Family caregivers are trying to balance their needs and aspirations as well as the responsibilities of the care role. While trying to do so, their quality of life can be adversely affected by this process. In this review, how the quality of life of family members caring for cancer patients is affected by the caregiving process and interventions for caregivers are presented. [ABSTRACT FROM AUTHOR]

The aim of this study examined the relationships between progesterone receptor (PR) and estrogen receptor (ER) status in meningiomas and tumor grade, proliferative index (Ki67), and prognosis. Immunohistochemistry with monoclonal rabbit antibodies was performed on 4 mm paraffin sections of all tumors that were confirmed as meningiomas. Samples were assessed for tumor grade, PR and ER expression, and Ki67 status. Correlations among these parameters and their prognostic values were investigated. Overall survival (OS) was 91.4 months, and there was a significant difference in OS between genders. OS for females and males was 100.2 and 45.7 months, respectively (p= 0.02). When patients were divided into two groups by age, there was a significant difference in OS between those aged 50 years and younger and those older than 50 years, 113.2 and 65.1 months, respectively (p= 0.001). There was also a significant difference in OS based on PR status. OS among PR-negative patients was 43.8 months, whereas it was 93.7 months in weakly positive patients, and 95.2 months in strongly positive patients (p= 0.035). Overall, 10 (13.5%) patients had ER expression detectable by the monoclonal antibody technique used. All ER-positive tumor samples were from female patients; all tumors from males were negative for ER staining. Female predominance of meningiomas as the most common primary intracranial neoplasm strongly suggests that sex hormones may affect meningioma growth. This study found that PR status was a prognostic factor in our meningioma series, as were gender and age. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to present the clinical and pathological features that effect the recurrence and malignancy by analysis of results of inverted papilloma surgery performed in our center. Materials and Methods: The data of 52 patients whom underwent surgery because of inverted papilloma at Department of Otorhinolaryngology, Istanbul Faculty of Medicine between 2008 and 2015 was investigated retrospectively. Demographic datas of patients, prior surgery, origin of tumor, stage, initial symptoms, and surgical techniques were evaluated. Results: The mean age of 52 patients whom were treated from inverted papilloma was 59.3±12.4, and age range was 32-84. 41 of 52 patients were male and 11 were female. The distribution of the patients according to Krouse Staging system was determined such as; 1 of patients was T4, 4 were T2, 41 patients were T3 and 6 were T4. In all, nine patients were found having squamous cell carcinoma or dysplasia. It is found that the smoking did not have an effect on recurrence (p=0.289) and prior surgery (p=0.748), prior surgery history was related to multiple location (p=0.043). The mean follow-up period was 49,5±26,6 and minimum and maximum follow-up periods were 2-96 months. The mean age recurrence time was found as 41.3 months. Conclusion: The most important factor to prevent the recurrence of inverted papilloma is to determine the location and to excise exactly. The relation of smoking and old surgery story with the reccurence could not be proved but it is seen that multiple location was related with repeating surgery. Larger case series and controlled studies are needed to obtain clearer statistical results. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 51-year-old postmenopausal woman who presented with a right adnexal mass. Ultrasound revealed a normal left ovary but an enlarged right ovary; in explorative laparotomy a solid- cystic mass was found in the right ovary; total abdominal hysterectomy and bilateral adnexectomy were performed. Pathological and immunohistochemical results led to the diagnosis of female adnexal tumor of probable Wolffian origin (FATWO); 1 year after surgery she was asymptomatic.

The adrenal localization of a primary non-Hodgkin lymphoma is rare. We report a case of a 51-year-old man with adrenal insufficiency, cough and elevated eritrosit sedimentation rate. Conventional imaging studies ultrasonography (US) and computed tomography (CT) demonstrated bilateral bulky adrenal masses, and whole-body F-18 fluorodeoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) showed that the masses and peripancreatic lymphadenopathy were the unique manifestations of this disease. The patient was eventually diagnosed with a diffuse large B-cell non-Hodgkin lymphoma after a CT-guided needle adrenal biopsy. The present case indicated that primary adrenal lymphoma should be included in the differential diagnosis of bilateral adrenal masses. [ABSTRACT FROM AUTHOR]

Inflammatory pseudotumor of the lung is an uncommon nonneoplastic tumor of unknown origin. This tumor typically manifests as a solitary, peripheral and sharply circumscribed mass. Multiple lesions are seen in about 5% of cases. Most of the patients are under 40 years of age and complain mainly of non-specific symptoms. Many synonyms have been used for this disease, usually in relation to the most represented cell type: plasma cell granuloma, inflammatory myofibroblastic tumor, fibroxanthoma, histiocytoma, or pseudoneoplastic pneumonia. [ABSTRACT FROM AUTHOR]

Carcinosarcoma of the urinary bladder is a rare neoplasm that is composed of malignant epithelial and mesenchymal components. Fewer than 80 cases have been reported worldwide, usually as case reports or a small series. A series of 221 cases using the Surveillance, Epidemiology and End Results (SEER) Program database has been reported recently. We present one case of carcinosarcoma that was managed by neoadjuvant chemotherapy and that achieved a complete pathological response. A 57-year-old male patient presented with a 2-month history of hematuria. Ultrasonography revealed a 4 cm mass in the bladder dome. A transurethral resection of the bladder tumor (TURBT) revealed a carcinosarcoma. The patient underwent subsequent neoadjuvant chemotherapy and radiotherapy. The pathology specimen examination revealed no residual tumor. The patient had no evidence of recurrence after 20 months. This patient is the second reported case of carcinosarcoma of the urinary bladder that achieved a complete pathological response after neoadjuvant chemotherapy. [ABSTRACT FROM AUTHOR]

Nöroblastoma is the most aggressive tumor of childhood malignancies but can undergo spontaneous regression at stage 4S. It is not stated that stage 4 neuroblastoma regress spontantaneously. A 10-month-old girl presented with lower extremity hypotonias. The magnetic resonance imaging (MRI) workup revealed giant pre and paravertebral mass extending from T2 to T10, which surrounded descendent aorta and extension through the intervertebral foramina into the epidural space with extreme compression of the spinal cord, and multifocal hepatic metastasis. A clinical and radiological diagnosis was stage IV neuroblastoma, but the patient's parents could not to take away the patient to the tertiary health center for chemotherapy/radiotherapy and surgery caused by socioeconomic factors. Fourteen months after the initial presentation, the patient returned with healing findings and but hemiparesis has continued. The second MRI workup revealed the local masses and hepatic metastasis completely regressed. The patient has been followed up and treated with physiotherapy. In this case, we want to emphasize of stage IV neuroblastoma that can undergo spontaneous regression. [ABSTRACT FROM AUTHOR]

Oncocytoma is a non-frequent renal neoplasm and it represents in a range from 3 to 9% all primary renal masses originated from parenchymal cells or stem cells. Oncocytomas are mostly asymptomatic,and the majority of tumors are discovered incidentally. This tumor clinically benign and excellent prognosis,rarely,invasive growing and distand metastasis may be seen. Granular forms of renal cell carcinoma and eosinophilic variant of chromophobe cell carcinoma is not always possible to distinguish from this tumor,therefore radical or partial nephrectomy is applied for treatment. In this article,we present and discuss clinical, treatment and histopathological features of two renal oncocytoma cases according to the current literature. [ABSTRACT FROM AUTHOR]

Copyright of Acta Odontologica Turcica is the property of Acta Odontologica Turcica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Exercise Therapy & Rehabilitation is the property of Yavuz Yakut and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)