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Introduction: Osmotic stress can significantly affect the survival and functioning of living organisms, particularly during vulnerable stages such as seed germination and seedling growth. To address this issue, advanced technologies like nanofertilizers have been developed to improve soil conditions and enhance plant growth in stressed ecosystems due to their multiple effects and efficient consumption. Methods: The objective of this study was to investigate the impact of potassium nano-silicate (PNS) on the physiological characteristics of maize seedlings and seed germination under various levels of osmotic stress induced by polyethylene glycol (PEG). The study considered two factors: two levels of PNS concentration (500 and 1000 ppm) and PEG-6000 solution with different osmotic stress levels (-2, -4, -6, and -8 bars). Results and discussion: The results demonstrated that the application of PNS at a concentration of 1000 ppm led to increased radicle length and hypocotyl length as well as fresh weight of maize seedlings. Furthermore, PNS at a concentration of 1000 ppm had a more beneficial effect on the germination rate of maize seedlings under osmotic stress compared to 500 ppm. Additionally, the application of PNS under osmotic stress conditions resulted in an increase in various physiological parameters, including protein content, chlorophyll a, chlorophyll b, total chlorophyll content, proline content, and the activity of catalase (CAT) and ascorbate peroxidase (AXPO) enzymes. These findings indicate that the use of PNS can have a positive impact on the physiological characteristics of maize seedlings and seed germination under osmotic stress conditions. Overall, this technology has the potential to enhance crop growth and yield in stressed ecosystems. By improving the survival and function of plants during vulnerable stages, such as seed germination and seedling growth, the application of PNS can contribute to more resilient agricultural practices and promote sustainable food production in challenging environments. [ABSTRACT FROM AUTHOR] more...

IntroductionOsmotic stress can significantly affect the survival and functioning of living organisms, particularly during vulnerable stages such as seed germination and seedling growth. To address this issue, advanced technologies like nanofertilizers have been developed to improve soil conditions and enhance plant growth in stressed ecosystems due to their multiple effects and efficient consumption.MethodsThe objective of this study was to investigate the impact of potassium nano-silicate (PNS) on the physiological characteristics of maize seedlings and seed germination under various levels of osmotic stress induced by polyethylene glycol (PEG). The study considered two factors: two levels of PNS concentration (500 and 1000 ppm) and PEG-6000 solution with different osmotic stress levels (-2, -4, -6, and -8 bars).Results and discussionThe results demonstrated that the application of PNS at a concentration of 1000 ppm led to increased radicle length and hypocotyl length as well as fresh weight of maize seedlings. Furthermore, PNS at a concentration of 1000 ppm had a more beneficial effect on the germination rate of maize seedlings under osmotic stress compared to 500 ppm. Additionally, the application of PNS under osmotic stress conditions resulted in an increase in various physiological parameters, including protein content, chlorophyll a, chlorophyll b, total chlorophyll content, proline content, and the activity of catalase (CAT) and ascorbate peroxidase (AXPO) enzymes. These findings indicate that the use of PNS can have a positive impact on the physiological characteristics of maize seedlings and seed germination under osmotic stress conditions. Overall, this technology has the potential to enhance crop growth and yield in stressed ecosystems. By improving the survival and function of plants during vulnerable stages, such as seed germination and seedling growth, the application of PNS can contribute to more resilient agricultural practices and promote sustainable food production in challenging environments. more...

Cancer is a severe health issue, and cancer cases are rising yearly. New anticancer drugs have been developed as our understanding of the molecular mechanisms behind diverse solid tumors, and metastatic malignancies have increased. Plantderived phytochemical compounds target different oncogenes, tumor suppressor genes, protein channels, immune cells, protein channels, and pumps, which have attracted much attention for treating cancer in preclinical studies. Despite the anticancer capabilities of these phytochemical compounds, systemic toxicity, medication resistance, and limited absorption remain more significant obstacles in clinical trials. Therefore, drug combinations of new phytochemical compounds, phytonanomedicine, semi-synthetic, and synthetic analogs should be considered to supplement the existing cancer therapies. It is also crucial to consider different strategies for increased production of phytochemical bioactive substances. The primary goal of this review is to highlight several bioactive anticancer phytochemical compounds found in plants, preclinical research, their synthetic and semi-synthetic analogs, and clinical trials. Additionally, biotechnological and metabolic engineering strategies are explored to enhance the production of bioactive phytochemical compounds. Ligands and their interactions with their putative targets are also explored through molecular docking studies. Therefore, emphasis is given to gathering comprehensive data regarding modern biotechnology, metabolic engineering, molecular biology, and in silico tools. [ABSTRACT FROM AUTHOR] more...

Cancer is a severe health issue, and cancer cases are rising yearly. New anticancer drugs have been developed as our understanding of the molecular mechanisms behind diverse solid tumors, and metastatic malignancies have increased. Plant-derived phytochemical compounds target different oncogenes, tumor suppressor genes, protein channels, immune cells, protein channels, and pumps, which have attracted much attention for treating cancer in preclinical studies. Despite the anticancer capabilities of these phytochemical compounds, systemic toxicity, medication resistance, and limited absorption remain more significant obstacles in clinical trials. Therefore, drug combinations of new phytochemical compounds, phytonanomedicine, semi-synthetic, and synthetic analogs should be considered to supplement the existing cancer therapies. It is also crucial to consider different strategies for increased production of phytochemical bioactive substances. The primary goal of this review is to highlight several bioactive anticancer phytochemical compounds found in plants, preclinical research, their synthetic and semi-synthetic analogs, and clinical trials. Additionally, biotechnological and metabolic engineering strategies are explored to enhance the production of bioactive phytochemical compounds. Ligands and their interactions with their putative targets are also explored through molecular docking studies. Therefore, emphasis is given to gathering comprehensive data regarding modern biotechnology, metabolic engineering, molecular biology, and in silico tools. more...

Assessment of risk in the field of nanotechnology requires an integrated multidisciplinary approach due to the complex and cross-disciplinary framework for materials and activities at the nanoscale. The present paper summarizes the workshop “Governance of emerging nano-risk in the semiconductor industry” held on April 26, 2018 in Brussels, Belgium. The event targeted representatives of stakeholder communities involved in the risk assessment and governance of the engineered nanomaterials. Nanoelectronics was selected as an impactful use case for risk assessment approaches and comparison to bottom-up nanofabrication. The workshop outlined key data gaps impeding successful assessment of risks associated with nanoparticle use in the industry, using the semiconductor industry as an example. The workshop outlined mitigation strategies informing future regulatory decisions and identified some directions for future efforts. more...

Nanomedicine, nanotecehnology, immunology, oncology, innovation Within this historical context, we proposed this Research Topic to Frontiers in Oncology, aiming to invite authors to publish the most recent scientific and technological advances in the field of nanomedicine. Keywords: nanomedicine; nanotecehnology; immunology; oncology; innovation EN nanomedicine nanotecehnology immunology oncology innovation 1 3 3 10/29/21 20211025 NES 211025 Nanomedicine is a scientific field that uses nanotechnology in the development of diagnostic and therapeutic solutions for medical purposes. [Extracted from the article] more...

The present era of nanotechnology has reached to a stage where scientist are able to develop and programme complex machines that are built at molecular level which can work inside the patient body. One such challenge is a nanorobot, which once thought to be a desire as came into reality now. The proposed application of nanorobot can range from common cold to dreadful diseases like cancer, Diabetes, influenza, cerebral aneurysm. This study of nanorobot serves as a lead to the field of nanomedicine. There are many applications for nanorobotic systems and its biggest impact would be in the area of medicine. This article deals with the nanorobotic design and their applications in molecular diagnosis. more...