346 results on '"longévité"'
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2. The quest for the Benjamin Button effect in Silicon Valley: Bioethical and ecological issues posed by the longevity and immortality industry.
- Author
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Madanamoothoo, Allane and Schoch, Patrice
- Subjects
- *
BIOETHICS , *LONGEVITY , *IMMORTALITY of the body , *MEDICAL technology ,SILICON Valley (Santa Clara County, Calif.) - Abstract
The attainment of longevity and immortality, long a theme of fairy tales and myths, has now become a real-world quest. Scientists, innovators, and elite Silicon Valley entrepreneurs are engaged in an epic mission to transcend mortal limits and defeat death using innovative biomedical technologies. From cryonics and plasma infusion to genetic editing and mind uploading, the development of such technologies has been gaining momentum in recent years. Such biomedical advances in longevity and immortality, if successful, will have implications not only for individuals but also for society. Given their exponential growth as a target of commercial investment, it is crucial to address the potential bioethical and ecological issues these technologies pose within the ecosystem. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
3. Living beyond age 105: When the improbable becomes reality.
- Author
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Meslé, France, Vallin, Jacques, Camarda, Carlo-Giovanni, Caporali, Arianna, Poniakina, Svitlana, Toussaint, Laurent, and Robine, Jean-Marie
- Subjects
AGE ,CENTENARIANS ,DATABASES ,LONGEVITY ,MORTALITY - Abstract
Copyright of Population & Sociétés is the property of Institut National d'Etudes Demographiques and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2024
- Full Text
- View/download PDF
4. Life Expectancy of Couples in Canada.
- Author
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AlFakhri, Marwa and Compton, Janice
- Subjects
- *
LIFE expectancy , *LIFE spans , *VITAL statistics , *EARLY death , *HUMAN Development Index , *RETIREMENT - Abstract
Although individual estimates of life expectancy are readily available, analogous couple-based estimates are not. The dearth of such estimates can be detrimental for couples undertaking important decisions together, such as retirement, savings, and other later-life considerations. Moreover, relying on available individual measures can be misleading because it results in overestimating the number of years the couple should expect to live together (joint life expectancy) and underestimating the number of years the widowed spouse expects to live (survivor life expectancy). In this article, we use data from the Longitudinal Administrative Database to provide benchmark estimates for joint and survivor life expectancy for Canadian couples and show how these estimates vary with the income and employment status of couples approaching retirement. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
5. Effect of alternating temperature and seeds storage duration on the germination of Thymus satureioides
- Author
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Brahim Ouahzizi, Hamza ElBouny, Khalid Sellam, Chakib Alem, and Abdelmonaim Homrani Bakali
- Subjects
ligneux bas, germination, température ,stockage ,longévité ,réhabilitation ,Agriculture - Abstract
Thymus satureioides Cosson is an endemic chamaephyte to Morocco and Algeria. It belongs to the Lamiaceae family and commonly used in traditional medicine. Its over-exploitation threatens its sustainability in many ecosystems in Morocco. This study aims to explore the effect of environmental factors (temperature and storage) on the germination capacity of the seeds of this species in order to contribute to contribute to the rehabilitation of degraded ecosystems of T. satureioides. Accordingly, seeds collected from natural plant populations were subjected to six alternating temperatures (40/25, 35/20, 30/15, 20/10, 15/5 and 10/0 °C with a 14/10 hr. thermoperiod) and three storage duration (3 years, 5 years and 8 years) under ambient laboratory conditions. The results indicate that the alternating temperature and the seed storage duration have a significant effect on the germination parameters according to the test of Student Newman and Keuls (SNK). The highest germination percentage 93% was recorded for the alternating temperature of 15/05 °C, while high alternating temperature 40/25 °C strongly inhibited the seed germination. The 20/10 °C temperature regime was the best in terms of higher capacity and speed germination as indicated by the germination index (7.7 %/day for 20/10 °C versus 0.5 %/day for 10/0 °C). Furthermore, these results show that seed stored for longer duration delayed germination and decreased the germination capacity and rate. Seeds stored at room condition retain seeds viability up to 3 years. However, after 5 and 8 years of storing, the germination percentage was significantly reduced (75.0 and 64.5% respectively), which also suggests a reduction of seed viability.
- Published
- 2022
- Full Text
- View/download PDF
6. Effets de l'âge parental sur les traits d'histoire de vie de la progéniture chez le mouflon d'Amérique (Ovis canadensis)
- Author
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Marchand, Emmanuelle, Festa-Bianchet, Marco, Marchand, Emmanuelle, and Festa-Bianchet, Marco
- Abstract
La structure d'âge d'une population peut varier considérablement au fil du temps. Par conséquent, des effets à long terme de l’âge parental sur la valeur adaptative à vie de leur progéniture pourraient engendrer des répercussions importantes sur la dynamique des populations. Malgré les études existantes portant sur les effets à court terme de l'âge des parents sur la valeur adaptative de leur descendant, peu d'entre elles se sont attardées sur les implications à long terme tout en prenant en considération le sexe de la progéniture et l'influence des pères. Mon projet de recherche, basé sur 50 ans de données recueillies sur une population sauvage de mouflons d'Amérique (Ovis canadensis), explore les effets de l'âge parental sur la masse à trois ans, le succès reproducteur à vie des femelles, et la longévité des descendants. Grâce à une base de données couvrant la durée de vie totale de plus de 500 individus, j'ai pu réaliser des analyses longitudinales, permettant ainsi de prendre en considération les variations individuelles de longévité parmi les parents. Cette approche me permet d'évaluer l'existence potentielle d'un filtre de survie chez les parents, susceptible de dissimuler ou d’amplifier les effets de l'âge parental sur la valeur adaptative des descendants. Les résultats obtenus révèlent une corrélation significative négative entre l'âge maternel et la longévité de la progéniture, possiblement plus marquée chez les filles que chez les fils. Une tendance similaire, mais non significative est présente avec l'âge paternel. On constate aussi que les mères jouissant d’une longévité plus élevée semblent donner naissance à des descendants bénéficiant d’une longévité supérieure. En effet, les descendants nés de mères à longue durée de vie (7 ans ou plus) présentent un avantage de longévité de presque un an et demi par rapport à ceux nés de mères dont la longévité est de 2 à 6 ans. Aucun effet significatif de l’âge des parents n’a été détecté sur la masse des descendan
- Published
- 2024
7. Mating harassment may boost the effectiveness of the sterile insect technique for Aedes mosquitoes
- Author
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Zhang, Dongjing, Maiga, Hamidou, Li, Yongjun, Bakhoum, Mame Thierno, Wang, Gang, Sun, Yan, Damiens, David, Mamaï, Wadaka, Bimbilé Somda, Nanwintoum Séverin, Wallner, Thomas, Bueno-Masso, Odet, Martina, Claudia, Kotla, Simran Singh, Yamada, Hanano, Lu, Deng, Tan, Cheong Huat, Guo, Jiatian, Feng, Qingdeng, Zhang, Junyan, Zhao, Xufei, Paerhande, Dilinuer, Pan, Wenjie, Wu, YU, Zheng, Xiaoying, Wu, Zhongdao, Xi, Zhiyong, Vreysen, Marc J.B., Bouyer, Jérémy, Zhang, Dongjing, Maiga, Hamidou, Li, Yongjun, Bakhoum, Mame Thierno, Wang, Gang, Sun, Yan, Damiens, David, Mamaï, Wadaka, Bimbilé Somda, Nanwintoum Séverin, Wallner, Thomas, Bueno-Masso, Odet, Martina, Claudia, Kotla, Simran Singh, Yamada, Hanano, Lu, Deng, Tan, Cheong Huat, Guo, Jiatian, Feng, Qingdeng, Zhang, Junyan, Zhao, Xufei, Paerhande, Dilinuer, Pan, Wenjie, Wu, YU, Zheng, Xiaoying, Wu, Zhongdao, Xi, Zhiyong, Vreysen, Marc J.B., and Bouyer, Jérémy
- Abstract
The sterile insect technique is based on the overflooding of a target population with released sterile males inducing sterility in the wild female population. It has proven to be effective against several insect pest species of agricultural and veterinary importance and is under development for Aedes mosquitoes. Here, we show that the release of sterile males at high sterile male to wild female ratios may also impact the target female population through mating harassment. Under laboratory conditions, male to female ratios above 50 to 1 reduce the longevity of female Aedes mosquitoes by reducing their feeding success. Under controlled conditions, blood uptake of females from an artificial host or from a mouse and biting rates on humans are also reduced. Finally, in a field trial conducted in a 1.17 ha area in China, the female biting rate is reduced by 80%, concurrent to a reduction of female mosquito density of 40% due to the swarming of males around humans attempting to mate with the female mosquitoes. This suggests that the sterile insect technique does not only suppress mosquito vector populations through the induction of sterility, but may also reduce disease transmission due to increased female mortality and lower host contact.
- Published
- 2024
8. Longevity records for the Wilson's Plover (Charadrius wilsonia) in Guadeloupe (French West Indies).
- Author
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Braquier, Malo, Levesque, Anthony, Delolme, Jérémy, and Francesiaz, Charlotte
- Abstract
Copyright of Journal of Caribbean Ornithology is the property of Society for the Conservation & Study of Caribbean Birds and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
9. [The myth of longevity, from dream to unreality].
- Author
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Robert J
- Subjects
- Humans, Life Expectancy, Longevity physiology
- Published
- 2024
- Full Text
- View/download PDF
10. Larval diet and temperature alter mosquito immunity and development: Using body size and developmental traits to track carry-over effects on longevity
- Author
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Mackay, Andrew J., Yan, Jiayue, Kim, Chang-Hyun, Barreaux, Antoine, Stone, Chris M., Mackay, Andrew J., Yan, Jiayue, Kim, Chang-Hyun, Barreaux, Antoine, and Stone, Chris M.
- Abstract
Background: Estimating arbovirus transmission potential requires a mechanistic understanding of how environmental factors influence the expression of adult mosquito traits. While preimaginal exposure to environmental factors can have profound effects on adult traits, tracking and predicting these effects remains challenging. Methods: Using Aedes albopictus and a structural equation modeling approach, we explored how larval nutrition and temperature jointly affect development rate and success, female body size, and whether these metrics capture carry-over effects on adult female longevity. Additionally, we investigated how larval diet and temperature affect the baseline expression of 10 immune genes. Results: We found that larval development success was primarily determined by diet, while temperature and diet both affected development rate and female body size. Under a low larval diet, pupal wet weight and wing length both declined with increasing temperature. In contrast, responses of the two morphometric measures to rearing temperature diverged when females were provided higher larval nutrition, with pupal wet weight increasing and wing length decreasing at higher temperatures. Our analyses also revealed opposing relationships between adult female lifespan and the two morphometric measures, with wing length having a positive association with longevity and pupal weight a negative association. Larval diet indirectly affected adult longevity, and the time to pupation was negatively correlated with longevity. The expression of eight immune genes from the toll, JAK-STAT and Imd pathways was enhanced in mosquitoes with higher nutrition. Conclusions: Our results highlight deficiencies from using a single body size measure to capture carry-over effects on adult traits. Further studies of larval development rate under varying environmental conditions and its potential for tracking carry-over effects on vectorial capacity are warranted.
- Published
- 2023
11. Les Gilets jaunes : une révolte sans fin ?
- Author
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BERNARD DE RAYMOND, Antoine, BONIN, Loïc, BORDIEC, Sylvain, CHIRON, Pierre, CLÉMENT, Karine, ELALAOUI, Charif, GRÉMION, Théo, LIOCHON, Pauline, RAVELLI, Quentin, and REUNGOAT, Emmanuelle
- Subjects
Comparative ethnography ,Social movements ,Mouvements sociaux ,Ethnographie comparée ,Longevity ,Révolte ,Mobilisations paradoxales ,Paradoxical mobilisation ,Longévité - Published
- 2023
12. Le Front national comme espace de luttes : dynamiques croisées de professionnalisation politique.
- Author
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BEAUVALLET, Willy and MICHON, Sébastien
- Abstract
Copyright of Politix is the property of De Boeck Universite and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
13. Comparaison de survie de cohortes entre les pays d'Europe centrale et orientale et les pays à longévité élevée.
- Author
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NEPOMUCENO, Marília R. and CANUDAS-ROMO, Vladimir
- Abstract
Copyright of Population (00324663) is the property of Institut National d'Etudes Demographiques and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
14. Prolonger la longévité par l'acupuncture et ses techniques associées ? A propos d'un cas clinique.
- Author
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Stéphan, Jean-Marc
- Subjects
- *
ACUPUNCTURE , *LONGEVITY , *HEAT shock proteins , *ALZHEIMER'S disease , *GLUTATHIONE - Abstract
Introduction. "Some people live up to 100 years old. How can they have such longevity? (Chapter 54 of Lingshu). When it was written a few centuries before our era, the Chinese were already wondering about how to prolong life in good health. Is it possible to use acupuncture, electroacupuncture or moxibustion in order to extend longevity according to the precepts of chapter 54 of Lingshu (tiannian) by applying the means and knowledge of the 21st century? Methods. From a case study, a 92-year-old woman, followed for 27 years, will be assessed the so-called "longevity" points, chosen from among all those who, according to the Bianque xinshu, written by Dou Cai in 1146, but also other more modern authors, have the peculiarity of strengthening the human body by toning qi and xue. The possible action of these points will be analyzed in the light of current scientific theories explaining the physiological aging. Results. Acupuncture and associated techniques could slow the aging of the body mainly by the establishment of protections (such as superoxide dismutase, glutathione peroxidase, etc.), with respect to oxidative stress and the production of free radicals but also by the system of protection of heat shock proteins (HSP), or by the possibility of acting on the glycation of proteins. However, as soon as the effect of aging does its work and the disease appears on the various systems: central nervous, immune, cardiovascular, pulmonary, locomotor, digestive, urinary, etc., many studies of experimental acupuncture, but also randomized controlled trials, or even meta-analyzes have still shown the interest of acupuncture and associated techniques as can be observed in Alzheimer's disease, in arterial hypertension or obstructive pulmonary disease. In this clinical case, acupuncture and its associated techniques therefore seemed to ensure a good quality of life for this 92-year-old woman, without any undesirable effects. Conclusion. Before the onset of illness, acupuncture, electroacupuncture and moxibustion could potentially increase life expectancy in good health in combination with correct physical activity and appropriate dietary habits. Nevertheless, it will be necessary to nuance the scope of the potential effects of acupuncture and associated techniques and to make the difference between the points called "longevity" to use in prevention, the same points that will be used as soon as the natural defenses are exceeded. [ABSTRACT FROM AUTHOR]
- Published
- 2019
15. Lutter contre le temps dans l’univers politique
- Author
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Godmer, Laurent
- Subjects
political profession ,démocratie ,parliament ,temporalidades ,parlamento ,democracy ,métier politique ,longevidad ,parlement ,democratic temporality ,local politics ,Temporalities ,profesión política ,durée ,longevity ,temporalités ,democracia ,politique locale ,política local ,longévité ,temporalité démocratique - Abstract
La démocratie est fondée sur l’incertitude. La courte durée des mandats des élus les oblige à lutter contre le temps pour mener une carrière politique. Pour comprendre les modalités de cette lutte, il est heuristique d’étudier le cas d’un élu, Jean Tiberi, un ancien maire de Paris ayant connu une longévité rare. Des pratiques temporelles lui permirent de durer, et de siéger durant un demi-siècle simultanément au Conseil de Paris et à l’Assemblée nationale. Il le fit grâce à un usage intensif et personnalisé du cumul des mandats et des fonctions et de deux dispositifs de gouvernement du temps, le fief et le chauffeur, qui l’aidèrent à faire reculer l’horizon de la fin de son règne sur son territoire d’élection. Le contrôle du territoire est en effet la clé d’un contrôle du temps. Cela eut cependant un coût, médiatique et judiciaire, et des effets sur l’exercice du mandat : le métier politique fut exercé de manière clientéliste, mais surtout de manière sélective, le professionnel de la politique siégeant a minima au parlement et se repliant de plus en plus sur un territoire restreint. Democracy is based on uncertainty. The short duration of mandates obliges politicians to fight against time so as to pursue a political career. It is heuristic to analyse the case of a former mayor of Paris, Jean Tiberi, whose longevity was exceptional, in order to understand the modalities of that fight. Temporal practices allowed him to last, and to remain a member of the Paris local council and of the National Assembly for half a century. He managed to do so thanks to an intense and personalized use of the cumulation of mandates and functions. Two devices were useful to govern time: the stronghold and the driver. They helped the politician to postpone the horizon of the end of his reign on his election territory. The control of the territory is indeed the key to the control of time. That system was costly, in terms of negative media coverage and because of judicial affairs, and it had effects on the way the mandate was exercised: it was exercised in a clientelistic fashion, but mostly in a selective fashion, the involvement of the professional politician in parliament being minimal, and his presence on on a very limited territory increasingly important. La democracia se basa en la incertidumbre. La corta duración de los mandatos de los representantes electos les obliga a luchar contra el tiempo para poder hacer una carrera política. Con el fin de comprender las modalidades de esta lucha, es heurístico estudiar el caso de un funcionario electo, Jean Tiberi, ex-alcalde de París que tuvo una longevidad poco común. Las prácticas temporales le permitieron durar y sentarse durante medio siglo simultáneamente en el Consejo de París y en la Asamblea Nacional, como diputado. Lo hizo mediante un uso intensivo y personalizado de múltiples mandatos y funciones, y de dos dispositivos de gobierno del tiempo, el feudo y el chófer, que le ayudaron a aplazar el horizonte del fin de su reinado en su territorio. El control del territorio es, en efecto, la clave del control del tiempo. Sin embargo, esto tuvo un coste, en términos de poder mediático y judicial, y tuvo efectos en el ejercicio del mandato: la profesión política se ejerció de forma clientelar, pero sobre todo de forma selectiva, puesto que este profesional político sesionó a minima en el parlamento, relegándose cada vez más en un territorio restringido.
- Published
- 2022
16. Couvertures multigenres (mixtes) du risque de longévité
- Author
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Bourassa, Olivier, Bélanger, Alain, Bourassa, Olivier, and Bélanger, Alain
- Abstract
Ce texte traite du risque de longévité et suggère une méthode afin de le couvrir efficacement à faible coût un portefeuille mixte (composé d'annuités d’hommes et de femmes). Le risque de longévité est un risque surtout applicable aux fonds de pension ainsi qu’aux compagnies d’assurance et est défini comme le risque qu’une population ou sous-population vive plus longtemps que l’avaient estimé les prévisions. En se basant sur des couvertures unigenres déjà existantes dans la littérature, nous réussissons à couvrir le risque de longévité pour des portefeuilles de rentiers mixtes. L’attrait principal est l’importante réduction d’écart-type, de VaR à 99\% et d’ES à 99\% en n’utilisant que la moitié des instruments dérivés (forward) originalement proposés par les auteurs.
- Published
- 2022
17. La mortalité différentielle selon le lieu de naissance au Canada : une étude de suivi sur la période 1991-2016
- Author
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Sucharczuk, Vanesa, Ouellette, Nadine, and Bourbeau, Robert
- Subjects
Natifs ,Lifespan disparity ,Canada ,Natives ,Longevity ,Longévité ,Mortality differentials ,Mortalité différentielle ,Immigrants ,Dispersion des durées de vie ,Lissage par P-splines ,Âge modal au décès ,P-splines smoothing ,Modal age at death - Abstract
Comme plusieurs pays industrialisés, le Canada fait face à un vieillissement de sa population qui est exacerbé par la baisse de la mortalité aux âges adultes et avancés. Pour atténuer les conséquences du vieillissement de la population, le Canada a recours à une immigration internationale qui s’est beaucoup diversifiée quant au lieu de naissance des arrivants depuis quelques décennies. Dans ce contexte, il est intéressant de s’interroger sur le comportement différentiel des immigrants selon leur provenance en comparaison avec les Canadiens de naissance. Notre recherche s’inscrit plus précisément sous la thématique mortalité et elle a pour objectif d’étudier les disparités dans la distribution des décès par âge et par sexe selon la provenance, cette dernière étant comprise d’une double manière, soit selon une perspective géographique, soit selon le niveau de développement du pays de naissance. En utilisant une approche de lissage par P-splines, nous estimons l’âge modal (i.e. le plus commun) au décès et la dispersion des durées de vie au mode pour les divers groupes d’immigrants à l’étude et les natifs. Nos résultats montrent que la mortalité aux grands âges résumée par l’âge modal au décès, M, est plus faible pour l’ensemble des immigrants qu’au sein de la population native. L’écart est plus élevé chez les hommes et relativement faible chez les femmes, tout en étant statistiquement significatif. La répartition des décès selon l’âge des immigrants est plus concentrée autour de son centre que celle des natifs, indiquant une plus grande homogénéité des durées de vie individuelles aux âges avancés. L’âge modal au décès estimé pour chacune des catégories de provenance considérées séparément, soit selon la région géographique, soit selon l’indice de développement humain, présente des différences statistiquement significatives par rapport à la population native, à l’exception des femmes Britanniques et celles de l’Afrique et du Moyen-Orient. De plus, certaines différences significatives en matière d’âge modal au décès sont observées lors de la comparaison des groupes d’immigrants entre eux. Le phénomène de sélection, à la fois dans le pays de provenance et dans celui de destination, est l’explication la plus plausible pour ces différences et elle est discutée dans ce mémoire., Like many industrialized countries, Canada is facing an aging population that is exacerbated by the decline in mortality in adulthood and advanced ages. To mitigate the consequences of an aging population, Canada has resorted to international immigration, which has greatly diversified in terms of the place of birth of arrivals in recent decades. In this context, it is interesting to study the differential behavior of immigrants according to their origin compared to native-born Canadians. Our research focuses specifically under the theme of mortality and its objective is to study the disparities in the distribution of deaths by age and sex according to origin, the latter being twofold, i.e., from a geographical perspective, or according to the level of development of the country of birth. Using a P-spline smoothing approach, we estimate the modal (i.e., the most common) age at death and the dispersion of mode lifespans for the various immigrant groups under study and natives. Our results show that mortality at older ages, summarized by the modal age at death, M, is lower among immigrants than for the native population. The difference is higher for men and relatively small for women, while still being statistically significant. The distribution of deaths by age of immigrants is more concentrated around its center than that of natives, indicating a greater homogeneity of individual lifespans at advanced ages. The estimated modal age at death for each of the categories of origin considered separately, either by geographic region or by HDI, shows statistically significant differences compared to the native population, with the exception of women from the United Kingdom and from Africa and the Middle East. In addition, some significant differences in the modal age at death are observed when comparing immigrant groups with each other. The phenomenon of selection in both the country of origin and the country of destination is the most plausible explanation for these differences and is discussed in this thesis.
- Published
- 2022
18. GROWTH PATTERN AND LONGEVITY OF PARAPENAEUS FISSUROIDESCROSNIER, 1985 (DECAPODA, PENAEIDAE) IN KAGOSHIMA BAY, SOUTHERN JAPAN.
- Author
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ZANNATUL FARHANA and JUN OHTOMI
- Subjects
- *
DECAPODA , *PENAEIDAE , *SHRIMPS , *BENTHIC animals - Abstract
Parapenaeus fissuroides Crosnier, 1985 is an emergent fisheries shrimp resource in the benthic community of Kagoshima Bay. The growth pattern and longevity of P. fissuroides were estimated from monthly length-frequency distributions. Carapace length (CL) ranged from 7.7-27.1 mm in males and 6.4-36.1 mm in females. Both males and females were recruited during late autumn and winter. Growth was best described by Pauly & Gaschütz's growth equation as Lt = 25.6(1 - exp(-1.011(t/12 + 0.539) - (0.641/2π) sin(2π(t/12 - 0.577)))) for males and Lt = 34.3(1 - exp(-0.941(t/12+0.227)-(0.581/2π) sin(2π(t/12-0.603)))) for females. Females grew faster and reached larger sizes than males of the same age group. The life-span of P. fissuroides was estimated to be around 2 years for males and 2.5 years for females. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
19. CLINICAL EVALUATION OF CLASS II COMPOSITE RESIN RESTORATIONS USING TWO DIFFERENT BULK-FILL TECHNIQUES.
- Author
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Kurdi, Rahaf and Abboud, Souad ali
- Subjects
- *
GUMS & resins , *PSYCHODIAGNOSTICS - Abstract
The purpose of the present study was to compare the clinical performance of class II composite resin restorations using two different bulk fill techniques according to the United States Public Health Service criteria (USPHS) over 12 months follow-up. Sixty class II restorations were placed in 60 patients, 20-50 years old. The patients were divided into three groups according to the applied restoration technique. In all cavities, etching (N Etch, Ivoclar Vivadent) was applied for 15 seconds and then rinsed. After that bonding was applied and cured for 20 seconds (N Bond, Ivoclar Vivadent). In group 1, Tetric Evo Ceram (Ivoclar Vivadent) was placed in 2 mm increments. In group 2, Tertic N Ceram Bulk Fill (Ivoclar Vivadent) was placed in single increment. In group 3, SonicFill (Kerr, Kavo) was placed in single increment by sonic vibration. The restorations were evaluated using modified USPHS criteria at baseline and then after 3, 6, 9 and12 months. After 12 months, 58 class II restorations were evaluated. Two cases were dropped out. All the restorations in the three groups showed acceptable clinical performance according to the modified USPHS criteria. The differences between the techniques weren't statistically significant. Overall success was 91.3%. Five restorations failed, one in the first group and four in the second group. Both bulk fill techniques performed well over the 12 months observation period. The bulk fill composite resin performed equally to the conventionally layered resin composite during the 12 months of the present clinical study. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
20. Extended longevity and survivorship during amino-acid starvation in a Drosophila Sir2 mutant heterozygote.
- Author
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Slade, Jennifer D., Staveley, Brian E., and Civetta, A.
- Subjects
- *
SURVIVAL analysis (Biometry) , *LONGEVITY , *DROSOPHILA genetics , *SIRTUINS , *HOMEOSTASIS , *AMINO acids in nutrition , *STARVATION , *LOW-calorie diet - Abstract
The regulation of energy homeostasis is pivotal to survive periods of inadequate nutrition. A combination of intricate pathways and proteins are responsible for maximizing longevity during such conditions. The sirtuin deacetylase Sir2 is well conserved from single-celled yeast to mammals, and it controls a number of downstream targets that are active during periods of extreme stress. Overexpression of Sir2 has been established to enhance survival of a number of model organisms undergoing calorie restriction, during which insulin receptor signalling (IRS) is reduced, a condition that itself can enhance survivorship during starvation. Increased Sir2 expression and reduced IRS result in an increase in the activity of the transcription factor foxo, an advantageous activation during stress but lethal when overly active. We have found that a lowered gene dosage of Sir2, in mutant heterozygotes, can extend normal longevity and greatly augment survivorship during amino-acid starvation in Drosophila. Additionally, these mutants, in either heterozygous or homozygous form, do not appear to have any disadvantageous effects upon development or cell growth of the organism unlike IRS mutants. These results may advance the understanding of the biological response to starvation and allow for the development of a model organism to mimic the ability of individuals to tolerate nutrient deprivation. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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21. Trends, patterns, and differentials in Canadian mortality over nearly a century (1921-2011).
- Author
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Bourbeau, Robert and Ouellette, Nadine
- Subjects
MORTALITY ,TRENDS ,REGIONAL economic disparities ,HUMAN Development Index ,GROSS domestic product - Abstract
Copyright of Canadian Studies in Population is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2016
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22. First approach to bone histology and skeletochronology of Equus hemionus.
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Nacarino-Meneses, Carmen, Jordana, Xavier, and Köhler, Meike
- Subjects
- *
SKELETOCHRONOLOGY , *ASIATIC wild asses , *FOSSIL mammals , *ONTOGENY , *HABITATS - Abstract
Histological approaches to extant mammalian life histories (LHs) provide the basis for reconstructing LHs of fossil mammals. They are of special interest in lineages such as perissodactyls that played a key role in fossil ecosystems. We studied an ontogenetic series of Equus hemionus (Asiatic wild ass), the most appropriate extant representative of fossil horses. We analyzed growth marks in femora of 10 specimens of different ontogenetic stages and habitats. Bone tissue types and vascular canal orientation vary both during ontogeny and within cross-sections. Skeletochronology generally fits previous age estimates from dental eruption patterns. Our wild adult female attained skeletal maturity at the age of four, the wild male at 5 years. Our results do not only contribute to our knowledge of Asiatic wild ass but they also show that bone histology is a valid tool in reconstructing LH evolution in the horse lineage. [ABSTRACT FROM AUTHOR]
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- 2016
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23. Trace lithium in Texas tap water is negatively associated with all-cause mortality and premature death.
- Author
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Fajardo, Val Andrew, LeBlanc, Paul J., and Fajardo, Val Andrei
- Subjects
- *
WATER pollution , *DEATH , *CAUSES of death , *LITHIUM , *LONGEVITY - Abstract
Lithium in tap water was previously found to have life-extending effects across 18 Japanese municipalities. Using a larger dataset with several Texas counties, our study shows that lithium concentrations in tap water are negatively associated with all-cause mortality ( r = −0.18, p = 0.006, 232 counties) and years of potential life lost ( r = −0.22, p = 0.001, 214 counties). Thus, our present findings extend and reinforce lithium's purported life-prolonging effect in humans. [ABSTRACT FROM AUTHOR]
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- 2018
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24. Le cerveau au grand âge
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Balard, Frédéric
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scientific categorizations ,lcsh:Sociology (General) ,catégorisations scientifiques ,longevity ,lcsh:GN1-890 ,grand âge ,brain ,lcsh:Anthropology ,lcsh:HM401-1281 ,cerveau ,longévité ,advanced age - Abstract
Au sein du corps humain, le cerveau constitue un organe particulier faisant l’objet de différentes conceptions et mesures scientifiques. Cet article propose d’aborder une partie de ces conceptions au prisme des recherches sur le grand âge et la longévité. En s’appuyant sur une analyse de la littérature en médecine, neuropsychologie, biologie et de psychologie expérimentale, l’article montre que les conceptions scientifiques du cerveau sont tout à la fois marquées par l’époque mais surtout par l’approche théorique et l’objet de la recherche dans lesquelles elles se trouvent prises. En cela, le cerveau est tantôt conçu comme un objet de mesure de l’âge en fonction de ses capacités d’homéostasie, de plasticité ou de résilience, tantôt comme un instrument support de la conscience, de la personnalité ou d’un comportement favorable ou non au bien vieillir. Dans une conception biologique, le cerveau apparait comme l’organe à partir duquel il est possible de lier des manifestations biologiques et des mesures cliniques de la démence. Il n’est pas un “morceau” de corps comme les autres mais l’organe qui révèle la maladie, l’âge voire l’être. In the human body, the brain constitutes a particular organ that is the object of various conceptions and scientific measurements. This article proposes approaching some of these conceptions in the prism of research work on advanced age and longevity. In being based on an analysis of the literature in medicine, neuropsychology, biology and experimental psychology, the article shows that the scientific conceptions of the brain are at once marked by the period but above all by the theoretical approach and the goal of the research they find themselves involved in. In that regard, the brain is sometimes conceived of as an object of measurement of age in terms of its capacities for homeostasis, plasticity or resilience, and sometimes as a support instrument of the consciousness, the personality or a behaviour that is favourable or not to aging well. Within a biological conception, the brain appears as the organ based on which it is possible to link biological manifestations and clinical measurements of insanity. It is not a “piece” of the body like the others but the organ which reveals disease, age and even being.
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- 2019
25. Secrets des entreprises familiales à forte longévité
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ALLALI, Brahim
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entreprise familiale ,lcsh:Commerce ,longévité ,lcsh:HF1-6182 ,lcsh:HF5546-5548.6 ,Entreprise familiale ,secrets ,lcsh:Office management - Abstract
Les études sur les entreprises familiales montrent que peu d’entre elles parviennent à survivre à leur transmission d’une génération à la suivante. Par-delà la divergence des raisons invoquées pour expliquer ce que certains qualifient d’hécatombe, il ne fait aucun doute que le choc de deux logiques difficilement conciliables : celle de la famille et celle des affaires, s’accapare l’essentiel de l’explication. Ainsi, le secret de la longévité de ces entreprises semble résider avant tout dans la manière dont la chefferie de la famille en affaires parvient à gérer cette zone d’entrecroisement entre les deux logiques. En effet, à travers la mise en place d’un ensemble de mécanismes permettant d’éviter les conflits d’intérêt et de logique, le leadership familial prévient les conflits et les problèmes. Et, quand bien même des conflits surgissent, il parvient, à l’aide de ces mécanismes à les traiter sans menacer l’harmonie de la famille ni la continuité de l’entreprise., Moroccan Journal of Entrepreneurship, Innovation and Management, Vol. 4, No 1 (2019)
- Published
- 2019
26. Life Course Predictors of Young Men Surviving to Age 90 in a Cohort Study: The Manitoba Follow-up Study.
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Tate RB, Swift AU, Thompson EH Jr, and St John PD
- Subjects
- Male, Humans, Aged, 80 and over, Young Adult, Adult, Child, Cohort Studies, Follow-Up Studies, Manitoba, Blood Pressure physiology, Risk Factors, Life Change Events
- Abstract
The purpose of this study was to identify factors at various time points in life that are associated with surviving to age 90. Data from men enrolled in a cohort study since 1948 were considered in 12-year intervals. Logistic regression models were constructed with the outcome of surviving to age 90. Factors were: childhood illness, blood pressure (BP), body mass index (BMI), chronic diseases, and electrocardiogram (ECG) findings. After 1996, the Short Form-36 was added. A total of 3,976 men were born in 1928 or earlier, and hence by the end of our study window in 2018, each had the opportunity of surviving to age 90. Of these, 721 did live to beyond his 90th birthday.The factors in 1948 which predicted surviving were: lower diastolic BP, lower BMI, and not smoking. In 1960, these factors were: lower BP, lower BMI, not smoking, and no major ECG changes. In 1972, these factors were lower BP, not smoking, and fewer disease states. In 1984, these factors were lower systolic BP, not smoking, ECG changes, and fewer disease states. In 1996, the factors were fewer disease states and higher physical and mental health functioning. In 2008, only higher physical functioning predicted survival to the age of 90. In young adulthood, risk factors are important predictors of surviving to age 90; in mid-life, chronic illnesses emerge, and in later life, functional status becomes predominant.
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- 2023
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27. Longevity and aging. Mechanisms and perspectives.
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Labat-Robert, J. and Robert, L.
- Subjects
- *
LONGEVITY , *AGING , *MEDICAL registries , *EPIGENETICS , *SIRTUINS - Abstract
Longevity can mostly be determined with relative accuracy from birth and death registers when available. Aging is a multifactorial process, much more difficult to quantitate. Every measurable physiological function declines with specific speeds over a wide range. The mechanisms involved are also different, genetic factors are of importance for longevity determinations. The best-known genes involved are the Sirtuins, active at the genetic and epigenetic level. Aging is multifactorial, not “coded” in the genome. There are, however, a number of well-studied physical and biological parameters involved in aging, which can be determined and quantitated. We shall try to identify parameters affecting longevity as well as aging and suggest some reasonable predictions for the future. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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28. L'effet des caractéristiques initiales des partenaires sur la longévité des joint ventures internationales en Méditerranée.
- Author
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TRIKI, DORA
- Abstract
Copyright of Management international / International Management / Gestiòn Internacional is the property of Management International and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
29. Covid-19: the three demographic shifts and their prospective
- Author
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Gérard-François Dumont, Espaces, Nature et Culture (ENeC), and Université Paris-Sorbonne (UP4)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
demography ,natality ,family policy ,nuptialité ,politique familiale ,espérance de vie ,population ,[SHS.DEMO]Humanities and Social Sciences/Demography ,longevity ,fertility ,démographie ,natural movement ,fécondité ,General Medicine ,[SHS.GEO]Humanities and Social Sciences/Geography ,prospective ,mouvement naturel ,mortality ,Longévité ,[SHS.SCIPO]Humanities and Social Sciences/Political science ,na-talité ,covid-19 ,nuptiality ,life expectancy ,France ,mortalité - Abstract
International audience; Foresight uses the word "rupture" when an evolution diverges from what could be envisaged by simply taking into account dynamics that are consistent with what has already been observed. Since the outbreak of the HIV-19 pandemic, this is exactly what population dynamics have shown, inviting us, for example in France, to distinguish between two types of rupture, one confirmed, the other two confirmed.; La prospective utilise le mot « rupture » lorsqu’une évolution diverge de ce qu’envisageait la seule prise en compte de dynamiques conformes à ce qui s’était déjà constaté. Depuis l’irruption de la pandémie covid-19, c’est exactement ce que montrent les dynamiques de population qui invitent, par exemple en France, à distinguer deux types de rupture, l’une confirmée, les deux autres actées.
- Published
- 2021
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30. Développement d’une méthodologie preuve de concept pour la recherche et la détermination des fonctionnalités des flores microbiennes et des aliments fermentés
- Author
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Cardin, Guillaume, STAR, ABES, Unité Mixte de Recherche sur le Fromage (UMRF), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Université Clermont Auvergne, Laurent Rios, and Stéphanie Bornes
- Subjects
[SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health ,[SDV.BIO]Life Sciences [q-bio]/Biotechnology ,Longevity ,Stress oxydatif ,Microorganisms ,Fromage au lait cru ,Microorganismes ,Longévité ,[SDV.BIO] Life Sciences [q-bio]/Biotechnology ,Raw-milk cheese ,[SDV.AEN] Life Sciences [q-bio]/Food and Nutrition ,Oxidative stress ,[SDV.EE.SANT] Life Sciences [q-bio]/Ecology, environment/Health ,Caenorhabditis elegans ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition ,Natural bioactive metabolite ,Métabolite naturel bioactif - Abstract
Natural products have always been a successful source of new drugs. Nowadays, the health sector (animal and human) is still looking for new compounds from natural resources, especially those which can exhibit a beneficial effect on the biological processes involved in the age-related affections (which have become a public health issue). The plants have already been investigating for this application. However, other natural resources, such as the microbial diversity, remain unexplored for the bioactivity of their compounds. The non-pathogenic microorganisms, especially those that can be found in fermented foods and drinks, could be considered as an interesting and innovative source of new metabolites that could exhibit beneficial effects. Among those fermented foods, the raw-milk cheese appears to have a great potential, as a source of new compounds, due to its rich microbial diversity. An innovative strategy was developed in this thesis with the aim of discovering new bioactive metabolites in a raw goat milk cheese. Several cheese extracts were obtained via an extraction method, which efficacity has been validated. The effect of the extracts on aging has been determined on in vitro and on in vivo models. Their impacts on the longevity of the nematode Caenorhabditis elegans, and on its survival on an oxidative medium have been evaluated. Some extracts (freeze-dried cheese, apolar extract and three aqueous extracts) have demonstrated beneficials effects during these experiments. Moreover, two signalling pathways (DAF-2/ILR pathway and p38 MAPK pathway) were identified to be involved in the mechanisms of action of the extracts. In parallel, two extracts (apolar extract and an aqueous extract) demonstrated a capacity to reduce the ROS production in human leukocytes. Finally, the study of the chemical composition of the bioactive extracts has begun, with the aim of determining the compounds that could be responsible of the biological activity and deserve to be isolated and studied. All the results obtained during this thesis are promising. The study of the chemical composition of the extracts will be pursued, as well as the study of their biological activity, especially on other in vitro and in vivo models more specific to aging., Depuis toujours, l’Homme a eu recours à la nature pour subvenir à ses besoins. Aujourd’hui encore, le secteur de la santé (animale et humaine) s’intéresse aux ressources naturelles pour découvrir des principes actifs originaux permettant de développer de nouveaux traitements. Ce secteur est notamment à la recherche de nouvelles molécules pouvant lutter contre les processus biologiques impliqués dans les affections liées au vieillissement, qui induisent une problématique de santé publique. Bien que la bioressource végétale ait été la plus étudiée pour ses propriétés pharmacologiques, d’autres ressources naturelles restent à explorer, telle que la bioressource microbienne. Les microorganismes non pathogènes, notamment ceux régulièrement consommés au travers des aliments et boissons fermentés, représentent une source intéressante de métabolites potentiellement actifs sur ces processus. Parmi ces aliments, le fromage au lait cru présente un fort potentiel grâce à la richesse de sa biodiversité microbienne. Une stratégie innovante a été développée au cours de cette thèse pour rechercher des métabolites bioactifs dans un caillé lactique caprin. Cette stratégie a permis l’obtention de plusieurs extraits de fromage, à l’aide d’une méthode d’extraction dont l’efficacité a été validée. Le criblage de l’effet des extraits sur le vieillissement a ensuite été réalisé à l’aide de modèles biologiques in vitro et in vivo. Leurs impacts sur la longévité du modèle Caenorhabditis elegans et sur sa survie sur un milieu oxydant ont notamment été évalués. Plusieurs des extraits (fromage lyophilisé, extrait apolaire, 3 extraits aqueux différents) ont par ailleurs montré des effets bénéfiques au cours de ces expériences. Les voies biologiques impliquées dans l’action des extraits ont également pu être identifiées (voie DAF-2/ILR et voie p38 MAPK). En parallèle, deux extraits (extrait apolaire et un des extraits aqueux) ont induit une diminution de la production de radicaux libres dans un modèle de leucocytes humains. Enfin, l’étude de la composition des extraits ayant présenté des résultats bénéfiques a débuté, avec pour objectif de cibler, parmi toutes les molécules les composant, celles pouvant être porteuses de l’activité biologique. L’ensemble des résultats obtenus est prometteur, et encourage à poursuivre les études de la composition des extraits issus du fromage ainsi que de leurs activités biologiques, notamment sur des modèles plus spécifiques du vieillissement.
- Published
- 2021
31. Stérilisation par irradiation de Glossina tachinoides Westw. pupae. II. Effets combinés du froid et des rayons gamma
- Author
-
Marc J.B. Vreysen and A.M.V. Van Der Vloedt
- Subjects
glossina tachinoides ,pupe ,stérilisation ,irradiation gamma ,résistance à la température ,azote ,lutte anti-insecte ,éclosion ,fertilité ,longévité ,Animal culture ,SF1-1100 - Abstract
Des femelles et des mâles de Glossina tachinoides Westwood ont été exposés, à l'état de pupes âgées de 5 jours, à une température de 15¼C pendant des périodes allant de 9 à 21 jours. Le développement pupal des femelles a été retardé de 10,4 et 18,4 j et celui des mâles de 9,9 et 18,4 j, pour les pupes dont la durée d'incubation était respectivement de 9 et 21 j. L'éclosion pupale n'a été troublée que pour les périodes de refroidissement excédant 15 jours. Une durée de refroidissement de 9 j n'a pas affecté la réponse à l'accouplement, l'aptitude à l'insémination et la fertilité des mâles exposés à l'état de pupes, mais leur durée de survie a été réduite de faéon significative de 52,1 ± 26,2 j à 35,3 ± 18,8 j. La survie des femelles adultes a été réduite, après exposition à l'état de pupes à des périodes de refroidissement dépassant 12 jours. En général, le taux d'éclosion, la fertilité des mâles et leur survie moyenne ont augmenté quand le traitement aux rayons a été effectué sous azote et lorsque le refroidissement et l'irradiation ont été appliqués tardivement dans la vie des pupes. La survie de toutes les femelles de l'expérience s'est trouvée réduite si on la compare à celle des animaux témoins. Leur réceptivité à l'accouplement est restée cependant normale dans la plupart des cas.
- Published
- 1995
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- View/download PDF
32. Stérilisation par irradiation de Glossina tachinoides Westw. pupae. I. Effet des doses fractionnées et de l’azote pendant l’irradiation à mi-course de la phase pupale
- Author
-
Marc J.B. Vreysen and A.M.V. Van Der Vloedt
- Subjects
glossina tachinoides ,pupe ,stérilisation ,irradiation ,azote ,fractionnement ,lutte anti-insecte ,éclosion ,fertilité ,longévité ,Animal culture ,SF1-1100 - Abstract
L'effet de l'azote pendant l'irradiation de pupes de Glossina tachinoides ainsi que le fractionnement des doses d'irradiation, ont été étudiés au milieu de la phase pupale. L'effet protecteur de l'azote contre des irradiations de 10 à 80 Gy de pupes âgées de 15 à 20 jours a été démontré par l'accroissement du taux global d'éclosion, par des niveaux plus élevés de fertilité résiduelle chez les mâles et par des durées de vie plus longues. La stérilité des màles traités par doses fractionnées séparées par 1 ou 2 jours a été identique à celle des mâles traités par une dose unique au 15e j après larviposition ; mais le taux de mutations létales induites était diminué pour des doses fractionnées séparées par un intervalle de 5 jours. La fécondité des femelles a été réduite lors du fractionnement de la dose d'irradiation à intervalle de 1 et 2 jours. Une stérilité complète a été obtenue chez les pupes femelles lorsque l'intervalle entre les doses fractionnées était de 5 jours, indépendamment de la dose utilisée.
- Published
- 1995
- Full Text
- View/download PDF
33. Financial issues in the viager market, actors' behaviour in the viager market, and actuarial contribution to longevity models
- Author
-
Coulomb, Jean-Baptiste, Dauphine Recherches en Management (DRM), Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres, and Arnaud Simon
- Subjects
Ageing ,Viager ,Lifetime annuity ,Longevity ,Rente viagère ,[SHS.GESTION]Humanities and Social Sciences/Business administration ,Immobilier ,Real estate ,Vieillissement ,Longévité - Abstract
In this thesis we were interested in studying the viager in many of its aspects, namely financials. This thesis is divided into five chapters, the first four studying the viager, and the last covering an actuarial aspect relating to longevity. The first chapter studies actors’ behaviour in the viager market through qualitative interviews. The second chapter studies the seller’s decision process through a questionnaire. The third chapter consists of a statistical study of the preference for the down-payment or the lifetime annuity and the determinants of negotiation, wealth extraction and annuitization. The fourth chapter is a study of the spatial dynamics of the viager in France. Finally, in the last chapter, the actuarial aspects of longevity are discussed, including a mathematical model for multiple populations.; Nous nous sommes intéressés dans cette thèse à étudier le viager immobilier sous plusieurs de ses aspects, notamment financiers. Cette thèse se divise en cinq chapitres, les quatre premiers étudiant le viager, et le dernier un aspect actuariel relatif à la longévité. Le premier chapitre se consacre à l’étude du comportement des acteurs du viager immobilier au travers d’interviews qualitatives. Le second étudie le processus de décision des vendeurs au travers d’un questionnaire. Le troisième consiste en une étude statistique de la préférence pour le bouquet ou la rente et des déterminants de la négociation, de l’extraction de richesse et de l’annuitisation. Le quatrième chapitre consiste en une étude de la dynamique spatiale du viager en France. Enfin, dans un dernier chapitre, les aspects actuariels de longévité sont abordés dont un modèle mathématique particulier pour de multiples populations.
- Published
- 2020
34. Enjeux financiers du viager, comportement des acteurs du viager, et contribution actuarielle aux modèles de longévité
- Author
-
Coulomb, Jean-Baptiste, Dauphine Recherches en Management (DRM), Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres, and Arnaud Simon
- Subjects
Ageing ,Viager ,Lifetime annuity ,Longevity ,Rente viagère ,[SHS.GESTION]Humanities and Social Sciences/Business administration ,Immobilier ,Real estate ,Vieillissement ,Longévité - Abstract
In this thesis we were interested in studying the viager in many of its aspects, namely financials. This thesis is divided into five chapters, the first four studying the viager, and the last covering an actuarial aspect relating to longevity. The first chapter studies actors’ behaviour in the viager market through qualitative interviews. The second chapter studies the seller’s decision process through a questionnaire. The third chapter consists of a statistical study of the preference for the down-payment or the lifetime annuity and the determinants of negotiation, wealth extraction and annuitization. The fourth chapter is a study of the spatial dynamics of the viager in France. Finally, in the last chapter, the actuarial aspects of longevity are discussed, including a mathematical model for multiple populations.; Nous nous sommes intéressés dans cette thèse à étudier le viager immobilier sous plusieurs de ses aspects, notamment financiers. Cette thèse se divise en cinq chapitres, les quatre premiers étudiant le viager, et le dernier un aspect actuariel relatif à la longévité. Le premier chapitre se consacre à l’étude du comportement des acteurs du viager immobilier au travers d’interviews qualitatives. Le second étudie le processus de décision des vendeurs au travers d’un questionnaire. Le troisième consiste en une étude statistique de la préférence pour le bouquet ou la rente et des déterminants de la négociation, de l’extraction de richesse et de l’annuitisation. Le quatrième chapitre consiste en une étude de la dynamique spatiale du viager en France. Enfin, dans un dernier chapitre, les aspects actuariels de longévité sont abordés dont un modèle mathématique particulier pour de multiples populations.
- Published
- 2020
35. Functional Characterization of Jouvence, a Small Nucleolar RNA Required in the Intestinal Epithelium in Drosophila
- Author
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Soulé, Stéphanie, Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay, Jean-René Martin, and STAR, ABES
- Subjects
Aging ,Lipd metabolism ,Petit ARN nucléolaire ,Longevity ,[SDV.BC]Life Sciences [q-bio]/Cellular Biology ,Vieillissement ,Longévité ,Intestin ,Intestine ,Small nucleolar RNA ,[SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology ,[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology ,[SDV.BC] Life Sciences [q-bio]/Cellular Biology ,Métabolisme des lipides - Abstract
The massive ageing of the population and the incredible leap in life expectancy in recent decades have led to an awareness of the importance of this problem. The need to better understand the mechanisms of ageing has become a public health emergency. Many research groups have been working for several years to identify genes and signalling pathways involved in the aging process.This biological process, which affects each species and each individual independently, is characterized by a gradual decline of function of many physiological processes as a function of age. However, even though it is inevitable, aging is still subject to influence. Indeed, many factors, both intrinsic (genetic factors, telomerases, oxidative stress) and environmental (lifestyle, diet, pollution) will influence aging. Aging is also an important risk factor for the development of many diseases such as type 2 diabetes, cancer, neurodegenerative and cardiovascular diseases. Moreover, it has already been reported in the literature that modulation of a single gene can influence, both positively and negatively, the aging process of an individual. More than the extension of life expectancy, it is a life expectancy without deficiency (concept of "aging well") that is the subject of major research. Genes with effects on this process are usually genes that play an important role in a signalling pathway, and therefore are often conserved across evolution. The work described in this thesis shows the involvement of a new snoRNA (jouvence), required in the intestinal epithelium, in the aging mechanisms of the fly D. melanogaster. In particular, they revealed the ability of this snoRNA to dramatically increase the lifespan of flies by halting the mechanisms of aging and fighting against the associated deleterious effects. jouvence would thus make it possible to fight against diseases associated with old age such as neurodegeneration, intestinal hyperplasia, but also against metabolic disorders, while prolonging the lifespan of the organism. This snoRNA appears to be involved in various metabolic pathways that may impact on long-term health of fruit flies. jouvence appears to regulate lipid metabolism, intestinal homeostasis, and stress resistance. On the other hand, its inactivation causes adverse effects that lead to the rapid degradation of several metabolic functions and premature death of flies. The results obtained in this study reveal a link between youthfulness and the control of healthy aging in D. melanogaster., Le vieillissement massif de la population et le bond incroyable ces dernières décennies de l’espérance de vie ont entraîné une prise de conscience de l’importance de ce problème. La nécessité de mieux appréhender les mécanismes du vieillissement est devenue une urgence de santé publique. De nombreux groupes de recherche se consacrent depuis quelques années à l'identification de gènes et de voies de signalisation impliqués dans le processus du vieillissement. Ce processus biologique, qui touche chaque espèce et chaque individu de manière spécifique, se caractérise par un déclin graduel de la fonction de nombreux processus physiologiques en fonction de l’âge. Toutefois même s’il est inéluctable, le vieillissement est influençable. En effet, de nombreux facteurs, autant intrinsèques (facteurs génétiques, télomérases, stress oxydatif), qu’extrinsèques (hygiène de vie, pollution, alimentation) vont influencer le vieillissement. C’est d’ailleurs un facteur de risque important dans le développement de nombreuses pathologies associées à l’âge (le diabète de type II, le cancer, les maladies neurodégénératives, les maladies cardiovasculaires). De plus, il a déjà été démontré dans la littérature que la modulation d’un seul gène peut influencer, autant positivement que négativement, le vieillissement d’un individu. Plus que l’allongement de la durée de vie, c’est une durée de vie sans déficience (concept du « bien vieillir ») qui fait l’objet des principales recherches. Les gènes ayant des effets sur ce processus sont habituellement des gènes jouant un rôle important dans une voie de signalisation et donc, sont souvent conservés à travers l’évolution. Les travaux décrits dans cette thèse concernent l’implication d’un nouveau snoARN (jouvence), requis dans l’épithélium de l’intestin, dans les mécanismes du vieillissement de la drosophile. Ils ont en particulier révélé la capacité de ce snoARN à augmenter de manière spectaculaire la durée de vie des mouches en enrayant les mécanismes du vieillissement et en luttant contre les effets délétères associés. jouvence permettrait ainsi de lutter contre les maladies associées à la vieillesse telles que la neurodégénérescence, l’hyperplasie intestinale, mais également contre les troubles métaboliques, tout en prolongeant la durée de vie de l’organisme. Il serait impliqué dans différentes voies métaboliques pouvant avoir un impact sur la santé à long terme des drosophiles. jouvence semble réguler le métabolisme lipidique, l’homéostasie intestinale, ainsi que la résistance au stress. Par contre, son inactivation de provoque des effets néfastes qui mènent à la dégradation rapide de plusieurs fonctions métaboliques et à la mort prématurée des mouches. Les résultats obtenus dans cette étude dévoilent un lien entre jouvence et le contrôle du vieillissement en santé chez la drosophile.
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- 2020
36. Internationalization and longevity of small- and medium-sized software firms.
- Author
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Ganesan, Vedavinayagam and Samii, Massood
- Subjects
GLOBALIZATION ,LONGEVITY ,SMALL business ,COMPUTER software industry ,MERGERS & acquisitions - Abstract
Copyright of Journal of Small Business & Entrepreneurship is the property of Routledge and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2014
- Full Text
- View/download PDF
37. Mitochondrial reactive oxygen species (ROS) in animal cells: relevance to aging and normal physiology1.
- Author
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Robb, Ellen L., Christoff, Casey A., Maddalena, Lucas A., and Stuart, Jeffrey A.
- Subjects
- *
MITOCHONDRIA , *REACTIVE oxygen species , *OXIDATION , *CHEMICAL reduction , *MANGANESE oxides - Abstract
In animal mitochondria, the four electron reduction of molecular oxygen to produce water at respiratory complex IV is the terminal step in substrate oxidation. However, respiratory complexes I, II, and III can participate in the single electron reduction of oxygen to produce the radical species superoxide. This progenitor reactive oxygen species (ROS) participates in a number of reactions that generate other ROS. These molecules may react with, and damage, intracellular macromolecules, leading to cellular dysfunction. Mitochondrial ROS production is often considered from this perspective of macromolecular damage and is central to the 'oxidative damage theory of aging', which suggests the accumulation of oxidative damage in animal cells underlies the aging phenotype and limits lifespan. In this review, we discuss some experimental results accumulated over the past decade that are inconsistent with this theory. A limitation of the theory is that it presupposes mitochondrial ROS are inherently harmful. However, it is increasingly apparent that some basic cellular functions are physiologically regulated by normal levels of mitochondrial ROS. For example, cell growth and division, the apoptotic pathway, and mitochondrial fusion-fission dynamics all appear to be redox-regulated by mitochondrial ROS and perhaps the matrix manganese superoxide dismutase (MnSOD). Therefore, it is less clear how the balance between ROS regulation of normal cellular activities and ROS-mediated macromolecular damage is maintained and how this relates to aging and longevity in animals. [ABSTRACT FROM AUTHOR]
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- 2014
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38. Mitochondrial reactive oxygen species (ROS) in animal cells: relevance to aging and normal physiology1.
- Author
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Robb, Ellen L., Christoff, Casey A., Maddalena, Lucas A., and Stuart, Jeffrey A.
- Subjects
MITOCHONDRIA ,REACTIVE oxygen species ,OXIDATION ,CHEMICAL reduction ,MANGANESE oxides - Abstract
Copyright of Canadian Journal of Zoology is the property of Canadian Science Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2014
- Full Text
- View/download PDF
39. Longevity and aging. Role of free radicals and xanthine oxidase. A review.
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Labat-Robert, J. and Robert, L.
- Subjects
- *
XANTHINE oxidase , *LONGEVITY , *AGING , *SIRTUINS , *LOW-calorie diet , *GENETIC markers , *FREE radicals - Abstract
Abstract: Longevity and aging are differently regulated. Longevity has an important part of genetic determinants, aging is essentially post-genetic. Among the genes involved in longevity determination, sirtuins, activated also by calorie restriction and some others as the TOR pathway, attracted special interest after the insulin–IGF pathway first shown to regulate longevity in model organisms. For most of these genes, postponement of life-threatening diseases is the basis of their action which never exceeds about 35% of all determinants, in humans. Among the post-genetic mechanisms responsible for age-related decline of function, free radicals attracted early interest as well as the Maillard reaction, generating also free radicals. Most attempts to remediate to free radical damage failed however, although different scavenger mechanisms and protective substances are present in the organism. Synthetic protectors were also tested without success. The only example of a successful treatment of a free radical mediated pathology is the case of xanthine oxidase, involved in cardiovascular pathology, essentially during the ischemia-reperfusion process. Its inhibition by allopurinol is currently used to fight this deadly syndrome. [Copyright &y& Elsevier]
- Published
- 2014
- Full Text
- View/download PDF
40. Gone With the Wind, 80 ans d’images. Entretien avec Pierre Berthomieu
- Author
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Emmeline Gros, Marie-Pierre Burquier, and Pierre Berthomieu
- Subjects
Hollywood ,lcsh:E11-143 ,Autant en emporte le vent ,media_common.quotation_subject ,affiches ,Art history ,America ,lcsh:History America ,Hollywood cinema ,longevity ,Gone with the Wind ,History America ,Gable (Clark) ,Mitchell (Margaret) ,E11-143 ,lcsh:E-F ,longévité ,cinéma hollywoodien ,posters ,Berthomieu (Pierre) ,media_common ,plasticité ,Clark Gable ,lcsh:America ,Leigh (Vivien) ,Art ,Object (philosophy) ,Wonder ,E-F ,Miracle ,plasticity - Abstract
In an interview with Gaumont’s artistic director Denis Peyrat, a journalist came to the conclusion that “film posters do not obey any miracle recipe.” However, when we consider the many posters of Gone With the Wind or when we talk about the film itself—a film that has survived the years and has never been the object of any remake—we can legitimately wonder if there are not any secret ingredients that would actually account for its longevity. These are some of the questions addressed in this interview with film scholar Pierre Berthomieu (Université de Paris), author of Hollywood, le temps des géants (Pertuis, Rouge profond, coll. “Raccords,” 2009). Dans son entretien avec Denis Peyrat, directeur artistique de Gaumont, un journaliste en vint à la conclusion que « l’affiche de film n’obéit à aucune recette miracle ». Pourtant, à considérer les nombreuses affiches du film Autant en emporte le vent ou le film lui-même – qui a traversé les années sans jamais faire l’objet d’un remake –, on peut légitimement se demander s’il n’y a pas des ingrédients secrets qui en expliqueraient la longévité. Ce sont là certaines des questions abordées dans cet entretien avec Pierre Berthomieu, chercheur en études cinématographiques à l’Université de Paris, auteur notamment de Hollywood, le temps des géants (Pertuis, Rouge profond, coll. « Raccords », 2009).
- Published
- 2020
41. Can historical demography benefit from the collaborative data of genealogy websites?
- Author
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Charpentier, Arthur, Gallic, Ewen, Université du Québec à Montréal = University of Québec in Montréal (UQAM), Centre de recherche en économie et management (CREM), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Aix-Marseille Sciences Economiques (AMSE), École des hautes études en sciences sociales (EHESS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Ces travaux de recherche ont été réalisés dans le cadre de l'Initiative de Recherche « Valorisation et nouveaux usages actuariels de l'information », placée sous l'égide de la Fondation du Risque en partenariat avec le GENES, l'Université de Rennes 1, l'Université Paris-Est La Vallée., Ces travaux ont également été soutenus par la subvention de l’Agence nationale de la recherche (ANR-17-EURE-0020)., ANR-17-EURE-0020,AMSE (EUR),Aix-Marseille School of Economics(2017), Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université de Caen Normandie (UNICAEN), and Normandie Université (NU)-Normandie Université (NU)
- Subjects
fertility ,[SHS.STAT]Humanities and Social Sciences/Methods and statistics ,fécondité ,données collaboratives ,[SHS.DEMO]Humanities and Social Sciences/Demography ,migration ,historical demography ,collaborative data ,mortality ,généalogie ,démographe historique ,genealogy ,longévité ,[SHS.HIST]Humanities and Social Sciences/History - Abstract
International audience; A growing number of websites offer users the possibility of building family trees. This article analyses the data collection and entry work of these users and how their results may be used in historical demography to further knowledge on past generations. To that end, the results obtained on the Geneanet website are compared with those established in the literature, concerning the entries of 2,457,450 French or French-origin individuals who lived in the 19th century. The comparison shows a considerable bias in the sex ratio, with women underrepresented. Fertility is also substantially underestimated. Regarding mortality, the data (compared with historical values) underestimate the mortality of men up to the age of 40 and that of women up to the age of 25, after which age it overestimates both. Lastly, the wealth of spatial characteristics contained in the family trees is also used to produce new data on internal migration in the 19th century.; Les sites qui proposent à leurs utilisateurs de reconstituer en ligne leur arbre généalogique fleurissent sur Internet. Cet article analyse le travail de collecte et de saisie effectué par ces utilisateurs et comment il pourrait être utilisé en démographie historique, afin de compléter la connaissance des générations du passé. Pour cela, les résultats obtenus à partir de la base Geneanet sont confrontés à ceux connus de la littérature, et concernent les enregistrements de 2 457 450 individus français ou d'origine française ayant vécu au xixe siècle. Est ainsi mis en évidence un biais important du rapport de masculinité (sous-représentation des femmes). La fécondité est elle aussi fortement sous-estimée. Quant à la mortalité, (par comparaison aux valeurs historiques), ces données sous-estiment la mortalité des hommes jusqu’à 40 ans environ et celle des femmes jusqu’à 25 ans, puis elles la surestiment. Enfin, la richesse des caractéristiques spatiales contenues dans les arbres généalogiques est également exploitée pour produire de nouvelles données sur les migrations internes au xixe siècle.
- Published
- 2020
- Full Text
- View/download PDF
42. [France: does the fall in the natural demographic surplus come from mortality or births?]
- Author
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Dumont, Gérard-François, Espaces, Nature et Culture (ENeC), and Université Paris-Sorbonne (UP4)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
fertility ,demography ,family policy ,[SHS.SOCIO]Humanities and Social Sciences/Sociology ,politique familiale ,démographie ,espérance de vie ,Longevity ,natural movement ,population ,fécondité ,[SHS.GEO]Humanities and Social Sciences/Geography ,mouvement naturel ,[SHS.DEMO]Humanities and Social Sciences/Demography ,mortality ,Longévité ,[SHS.SCIPO]Humanities and Social Sciences/Political science ,natalité ,birth ,life expectancy ,France ,mortalité - Abstract
International audience; [Among France's demographic dynamics, it should be noted that growth has fallen due to a natural balance that has been in marked decline in recent years. Should such a trend only be observed or can it be explained?]; Parmi les dynamiques démographiques de la France, il faut constater une croissance abaissée du fait d’un solde naturel en nette diminution ces dernières années. Une telle évolution doit-elle seulement être constatée ou peut-elle être expliqué ?
- Published
- 2020
- Full Text
- View/download PDF
43. Politiques sociales de la vieillesse et de la longévité : recul de la solidarité nationale et réémergence des solidarités familiales
- Author
-
Sophie Rozez
- Subjects
famille ,social protection systems ,aging ,solidarité ,Geology ,Ocean Engineering ,dépendance des personnes âgées ,family cares ,protection sociale ,longevity ,obligation alimentaire ,aide sociale ,aidants ,solidarities ,vieillesse ,assurances sociales ,care ,longévité ,social security ,welfare state ,dependency ,Water Science and Technology - Abstract
L’allongement de l’espérance de vie et le vieillissement de la population en France mettent à l’épreuve les systèmes de protection sociale mis en place au cours du XXe siècle. Ces derniers, qu’il s’agisse de la sécurité sociale ou de l’aide sociale, fondés historiquement sur la solidarité nationale ne permettent déjà plus de satisfaire les besoins des plus âgés. En particulier le risque de dépendance qui affecte les plus âgés, n’est pas pris en compte au titre de la sécurité sociale. Les solidarités collectives jusque-là mises en œuvre par l’Etat s’éclipsent au profit de dispositifs légaux mettant à contribution les membres de la famille. Ce retour à des solidarités familiales paraît bien témoigner d’un désengagement de l’Etat social. Increasing life expectancy and the aging of the population in France are testing the social protection systems put in place during the 20th century. These systems, whether social security or social assistance, historically based on national solidarity, no longer meet the needs of the elderly. In particular, the risk of dependency which affects older people is not taken into account under social security. The collective solidarities hitherto implemented by the State have been eclipsed in favor of legal systems involving the members of the family. This return to family solidarity seems to bear witness to a disengagement from the welfare state.
- Published
- 2020
44. Effects of feeding 10% rapeseed meal (Brassica napus) during gestation and lactation over three reproductive cycles on the performance of hyperprolific sows and their litters.
- Author
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Quiniou, N., Quinsac, A., Crépon, K., Evrard, J., Peyronnet, C., Bourdillon, A., Royer, E., and Etienne, M.
- Subjects
GLUCOSINOLATES ,RAPESEED ,PREGNANCY ,LACTATION ,SOWS ,ANIMAL litters ,SWINE - Abstract
The article discusses a study to determine long-term effects of dietary glucosinolates (GSL) when feeding solvent-extracted rapeseed meal (RM) during gestation and lactation of hyperprolific sows and their litters. The study suggests that dietary RM inclusion does not affect piglet weight at birth or weaning. The study further suggests that thyroid function of sows and piglets was not altered by RM inclusion.
- Published
- 2012
- Full Text
- View/download PDF
45. La durée de vie la plus commune des adultes au XVIIIe siècle : l'expérience des Canadiens-français.
- Author
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OUELLETTE, Nadine, ROBINE, Jean-Marie, BOURBEAU, Robert, and DESJARDINS, Bertrand
- Subjects
LONGEVITY ,ADULTS ,POPULATION ,MORTALITY ,LIVING conditions ,FRENCH-Canadians ,EIGHTEENTH century - Abstract
Copyright of Population (00324663) is the property of Institut National d'Etudes Demographiques and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2012
- Full Text
- View/download PDF
46. Survival advantage of siblings and spouses of centenarians in 20th-century Quebec.
- Author
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Jarry, Valérie, Gagnon, Alain, and Bourbeau, Robert
- Subjects
LONGEVITY ,SIBLINGS ,DEMOGRAPHIC surveys ,FAMILY demography ,MORTALITY - Abstract
Copyright of Canadian Studies in Population is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2012
47. EFFECTS OF TEMPERATURE ON SURVIVAL, GROWTH, REPRODUCTIVE AND LIFE SPAN CHARACTERISTICS OF BRANCHINECTA ORIENTALIS G. O. SARS, 1901 (BRANCHIPODA, ANOSTRACA) FROM IRAN.
- Author
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Atashbar, Behroz, Agh, Naser, Beladjal, Lynda, Jalili, Reza, and Mertens, Johan
- Subjects
- *
BRANCHINECTA , *BRANCHIPODIDAE , *SHRIMP populations , *SHRIMPS , *EGG incubation , *SEXUAL maturity in fishes , *REPRODUCTION - Abstract
Branchinecta orientalis G. O. Sars, 1901 is a common inhabitant of seasonal water catchments in the northwest of Iran. Hatching, growth, survival, and reproductive characteristics of this species were studied at different temperatures in the laboratory. The Cumulative Hatching Success was significantly higher for specimens cultured at 21°C (85.27 ± 12.21%) compared to those hatched at 12, 15 and 27°C ( P < 0 . 05 ). Hatching started on the same day (48.00 h after inundation) at temperatures of 21, 24 and 27°C), whereas this took more time at lower temperatures, slowest at 12°C (126.00 ± 0.58 h after inundation). The initial hatching fraction was the highest at 21°C (44.60 ± 18.69%) and lowest at 12°C (9.10 ± 8.28%). Total length was significantly longer at high temperatures, 12.38 ± 0.71 mm at 27°C, compared to 4.07 ± 0.42 mm at 12°C on day 15. Nevertheless, contrasting results were obtained for survival, being the lowest at 27°C (22 ± 4.00%) and highest at 12°C (93.07 ± 2.08%) on day 15 of growth. The animals reached sexual maturity significantly faster at 27°C (9.38 ± 1.09 days) compared to all other treatments. A significantly longer life span was detected at 12 and 15°C (63 days), and the higher cyst production at 18°C, compared to other experimental conditions ( P < 0.05). [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
48. Perdurabilidad empresarial: concepto, estudios, hallazgos.
- Author
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Rivera Rodríguez, Hugo Alberto
- Subjects
INDUSTRIAL management ,PROFITABILITY ,SUSTAINABLE development ,BUSINESS development ,STRATEGIC planning ,FINANCIAL performance - Abstract
Copyright of Cuadernos de Administración is the property of Universidad del Valle and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2012
- Full Text
- View/download PDF
49. The Low Mortality of a Learned Society.
- Author
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Winkler-Dworak, Maria
- Subjects
DEATH rate ,LEARNED institutions & societies ,MEMBERSHIP in associations, institutions, etc. ,EPIDEMIOLOGY ,LONGEVITY - Abstract
Copyright of European Journal of Population is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2008
- Full Text
- View/download PDF
50. Intracellular glasses and seed survival in the dry state
- Author
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Buitink, Julia and Leprince, Olivier
- Subjects
- *
GERMINATION , *DRYING , *CURING , *VISCOSITY , *CYTOPLASM , *FOURIER transform infrared spectroscopy - Abstract
Abstract: So-called orthodox seeds can resist complete desiccation and survive the dry state for extended periods of time. During drying, the cellular viscosity increases dramatically and in the dry state, the cytoplasm transforms into a glassy state. The formation of intracellular glasses is indispensable to survive the dry state. Indeed, the storage stability of seeds is related to the packing density and molecular mobility of the intracellular glass, suggesting that the physico-chemical properties of intracellular glasses provide stability for long-term survival. Whereas seeds contain large amounts of soluble non-reducing sugars, which are known to be good glass formers, detailed in vivo measurements using techniques such as FTIR and EPR spectroscopy reveal that these intracellular glasses have properties that are quite different from those of simple sugar glasses. Intracellular glasses exhibit slow molecular mobility and a high molecular packing, resembling glasses made of mixtures of sugars with proteins, which potentially interact with additional cytoplasmic components such as salts, organic acids and amino acids. Above the glass transition temperature, the cytoplasm of biological systems still exhibits a low molecular mobility and a high stability, which serves as an ecological advantage, keeping the seeds stable under adverse conditions of temperature or water content that bring the tissues out of the glassy state. To cite this article: J. Buitink, O. Leprince, C. R. Biologies 331 (2008). [Copyright &y& Elsevier]
- Published
- 2008
- Full Text
- View/download PDF
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