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BACKGROUND The B-Laser™ atherectomy system (Eximo Medical, Israel) is a 355 nm solid-state Nd:YAG short pulse laser for de-novo and restenotic infrainguinal PAD with enhanced affinity for atheroma and calcified plaque. METHODS The study was a prospective, single-arm, multi-center, international, open-label study assessing the B-Laser™ in symptomatic (Rutherford 2 to 4) infrainguinal peripheral artery disease. Primary core lab efficacy was mean reduction in diameter stenosis >20% by the B-Laser™ catheter alone. Cardiovascular death, major amputation, target lesion revascularization, WIQ, ABI and Rutherford class were obtained at baseline and out to 6 months. Duplex ultrasound patency (PSVR

RESUMEN Existen pocos estudios que comparen la adaptación de cofias de Cobalto-Cromo (Co-Cr) fabricadas por la técnica de cera perdida colada por centrifugación por inducción (CPCI) y fusión selectiva láser (SLM) en diseño y fabricación asistida por computador (CAD/CAM). Objetivo: Evaluar in vitro la adaptación marginal e interna de cofias unitarias de aleación Co-Cr sobre una línea de terminación tipo chamfer, fabricadas con la técnica CPCI y SLM en CAD/CAM. Material y Métodos: Se fabricaron 13 cofias de aleación Co-Cr para cada técnica. Se evaluó la adaptación marginal e interna utilizando la técnica de réplica de silicona. Cada réplica fue seccionada en sentido vestíbulo-palatino y mesio-distal para luego ser analizadas a nivel cervical, axial y oclusal mediante un estéreomicroscopio con aumento de 40X. Resultados: La discrepancia marginal de las cofias Co- Cr fabricadas por la técnica SLM fue 38.1μm y para la técnica CPCI fue 42,22μm sin diferencias significativas (p>0,05). La discrepancia axial para las cofias fabricadas por técnica CPCI fue de 42,02μm y para la técnica SLM de 60,16μm con diferencia significativa (p 0.05). The axial discrepancy for the copings manufactured by CPCI technique was 42.02 μm and for the SLM technique of 60.16 μm with significant difference (P < 0.05). The occlusal discrepancy for the copings made by the CPCI technique was 101.94 μm and for the SLM technique was 232.13 μm with significant difference (P < 0.05). Conclusions: The marginal adaptation was similar for CPCI and SLM techniques but without statistically significant differences. The internal adaptation was better for the CPCI technique than for the SLM technique with statistically significant differences.

Purpose: To report the first case of Neodymium Yttrium Aluminum Garnet (Nd:YAG) laser use to recanalize a CyPass occluded with a clot in the early postoperative follow-up. Observations: A 66 year-old woman with primary open angle glaucoma and cataract received combined cataract surgery plus CyPass in the right eye. Surgery was uneventful, however, there was a small amount of hyphema related to bleeding around the site of Cypass insertion. Intraocular pressure (IOP) was between 6 and 7 mmHg in the first week on no glaucoma medications. At the second postoperative week, IOP jumped to 30 mmHg and a clot was observed obstructing the CyPass lumen. We disrupted the clot with a single shot from a Nd:YAG laser. Twenty minutes after the laser, the IOP was 8 mmHg. CyPass was recanalized without complications. IOP was 11 mmHg at 1 month postoperatively with timolol 0.5% twice a day. Conclusions and importance: It is important to perform gonioscopy to evaluate for CyPass obstruction in cases of IOP spike. Nd:YAG laser may be a useful approach to recanalize the CyPass in the early postoperative follow-up. Keywords: Glaucoma, Lasers solid-state, Cataract extraction

Purpose: To report two cases of neurotrophic keratitis (NK) after micropulse transscleral cyclophotocoagulation (MP-TCP). Observations: Two patients with predisposing factors for decreased corneal sensation developed NK 1 month after MP-TCP. Both patients did not heal with initial treatment with topical antibiotic and preservative free artificial tears. One patient required use of a bandage contact lens and the other patient required tarsorrhaphy. Both eyes experienced recurrence of NK. Conclusions and importance: NK can be triggered after MP-TCP in patients with underlying predisposing factors for decreased corneal sensation. This uncommon but vision-threatening complication should be discussed preoperatively with high-risk patients as a possible adverse event after MP-TCP and followed closely postoperatively. Keywords: Glaucoma, Lasers solid-state, Micropulse transscleral cyclophotocoagulation, Neurotrophic keratitis

Nuevas tecnologías nos han permitido migrar de la técnica de cera perdida colada por centrifugado (CPC) a la fabricación aditiva como la fusión selectiva por láser (SLM), proporcionando una mejor adaptación marginal e interna. Objetivos: Comparar la discrepancia marginal e interna en cofias unitarias de Co-Cr sobre 2 líneas de terminación: chamfer y bisel, fabricadas con la CPC y SLM, determinando cual tuvo mejor adaptación marginal e interna. Material y Métodos: Se tuvo 4 grupos de estudio: CPC chamfer (n=13), CPC bisel (n=13), SLM chamfer (n=13) y SLM bisel (n=13). Para evaluar la discrepancia marginal e interna se usó el método de la réplica en silicona, seccionando primero en sentido vestíbulo-palatino (V-P) y segundo en sentido mesio-distal (M-D). Se midió las zonas cervical, axial y oclusal con un estéreo microscopio a 40X. Resultados: Se evaluó los supuestos de normalidad con la prueba de Shapiro-Wilk, y el análisis estadístico fue con las pruebas t de Student y U Mann-Whitney. La menor discrepancia marginal fue para la SLM chamfer con promedios menores de 24,70±10,29 μm en el corte V-P y de 21,82±5,94 μm en el corte M-D, seguido por la SLM bisel en el corte V-P de 34,12±16,23 μm y en el corte M-D de 35,34±8,91 μm. La CPC bisel en el corte V-P fue de 27,17±21,11 μm y en el corte M-D de 47,91±16,77 μm y para la CPC chamfer en el corte V-P fue de 89,65±58,39 μm y en el corte M-D de 91,72±67,13 μm; la diferencia fue estadísticamente significativa solo para las cofias de SLM chamfer comparándolas con la CPC chamfer. En la discrepancia interna los valores en los 4 grupos no tuvieron diferencias estadísticas. Conclusiones: Según los valores, la mejor adaptación marginal fue para la SLM cham- fer, seguida por la SLM bisel, CPC bisel y la CPC chamfer. En cuanto a la adaptación interna, los valores no fueron concluyentes para decir que técnica fue mejor, pero se logró mejor adaptación en la zona axial que la zona oclusal. New technologies have allowed us to migrate from the spin-wax casting technique (CPC) to additive manufacturing such as selective laser fusion (SLM), providing a better marginal and internal adaptation. Objectives: To compare the marginal and internal discrepancies in Co-Cr unit metal copings on two termination lines: chamfer and bevel, made with CPC and SLM, determining which technique had the best marginal and internal adaptation. Material and Methods: We had 4 study groups: CPC chamfer (n=13), CPC bevel (n=13), SLM chamfer (n=13), SLM bevel (n=13). To assess marginal and internal discrepancies, the silicone replica technique was used, a first sectioning was performed in the vestibular-palatine (V-P) and a secondin the mesio-distal (M-D) direction. The cervical, axial and occlusal zones were measured in a stereomicroscope at 40X. Results: Normality assumptions were evaluated with the Shapiro-Wilk test. Statistical analyzes were Student’s t test and U Mann-Whitney test. The less discrepancy marginal was for the SLM chamfer with mean values less than 24.70±10.29 μm in the V-P cut and 21.82±5.94 μm in the M-D cut, followed by the SLM bevel in the P-V cut of 34.12±16.23 μm and in the cut M-D of 35.34±8.91 μm. The CPC bevel in the V-P cut was 27.17±21.11 μm and in the M-D cut of 47.91±16.77 μm and for the CPC chamfer in the V-P cut was 89.65±58.39 μm and in the M-D cut of 91.72±67.13 μm; the difference was statistically significant only for SLM chamfer copings compared to the CPC chamfer. In the internal discrepancy values, no statistical differences were found among the 4 groups. Conclusions: Accord- ing to the descriptive values the best marginal fit was achieved with the SLM chamfer, followed by the SLM bevel, CPC bevel and CPC chamfer. Regarding internal adaptation, the descriptive values were not conclusive enough to decide which technique was better, but a better adaptation was achieved in the axial zone than in the occlusal zone.

We report the first oscillation achieved on 1 at. % Yb-doped Sc2O3 and Lu2O3 ceramics under quasi-CW pumping at 968 nm . With Sc2O3 we measured a maximum output power of 2.2 W with a slope efficiency of 59% at 1040.5 nm . Comparable results are obtained with Lu2O3 at 1032.5 nm , i.e., 1.8 W with a corresponding slope of 45%, while at 1078 nm we measured 1.5 W with 34% of slope efficiency. Finally, we present the range of tunability, which exceeds 41 nm for both samples. To the best of our knowledge, these are the first measurements reported in literature either in terms of laser emission or continuous tunability range achieved with 1 at. % doping level.