1. The role of vitamin D and its analogues in the treatment of oral mucosal diseases and periodontal diseases
- Author
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WU Qian, WANG Jian, NIU Li, YANG Xue, and TANG Xiaolin
- Subjects
vitamin d, ,analogues, ,calcium and phosphorus metabolism, ,vitamin d receptor, ,hypercalcemia, ,hypercalciuria, ,immunity, ,inflammation, ,Medicine - Abstract
Vitamin D is an essential nutrient in the body. In recent years, increasing attention has been paid to its role in regulating immunity and anti-inflammatory effects. However, the application of vitamin D in vivo may produce some side effects, such as hypercalcemia and hypercalciuria. Some analogs of vitamin D obtained through molecular modification can reduce the side effects while retaining a similar regulatory action as that of vitamin D. The supplementation of vitamin D or the use of vitamin D analogs may contribute to the prevention and treatment of immune inflammatory diseases. This article reviews the role of vitamin D and its analogues in the prevention and treatment of oral mucosal diseases and periodontal diseases. The literature review results show that vitamin D and its analogues can protect the integrity of the oral mucosal barrier, prevent or delay the occurrence of oral lichen planus, and provide a reference value for the prevention and treatment of periodontitis.
- Published
- 2019
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