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3 results on '"identical meals"'

1. Identification of Human Intestinal Microbiota of 92 Men by Data Mining for 5 Characteristics, i.e., Age, BMI, Smoking Habit, Cessation Period of Previous Smokers and Drinking Habit

Author

Toshiya Toda, Naoki Sato, Kenji Fujiwara, Jong-Sik Jin, Mitsuharu Matsumoto, Genichirou Seo, Toshio Kobayashi, Yoshiko Benno, Masaki Shimakawa, Isao Matsuda, Osamu Chounan, Yoshimi Benno, Toshiya Maruo, Ryoko Kibe, Yoshiki Tanaka, Mutsumi Touyama, and Hiroyuki Tagami

Subjects
Identification methods, Smoking habit, Immunology, computer.software_genre, Applied Microbiology and Biotechnology, Microbiology, operational taxonomic units, node, Data mining software, Correlation, decision tree, Data Noise, Medicine, discrimination of subjects, human intestinal microbiota, Full Paper, business.industry, Gastroenterology, identical meals, Drinking habits, Identification (biology), terminal restriction fragment length polymorphism, Data mining, business, computer, Body mass index, Food Science
Abstract

The intestinal microbiota compositions of 92 men living in Japan were identified following consumption of identical meals for 3 days. Fecal samples were analyzed by terminal restriction fragment length polymorphism with 4 primer-restriction enzyme systems, and the 120 obtained operational taxonomic units (OTUs) were analyzed by Data mining software focusing on the following 5 characteristics, namely, age, body mass index, present smoking habit, cessation period of previous smokers and drinking habit, according to the answers of the subjects. After performing Data mining analyses with each characteristic, the details of the constructed Decision trees precisely identified the subjects or discriminated them into various suitable groups. Through the pathways to reach the groups, practical roles of the related OTUs and their quantities were clearly recognized. Compared with the other identification methods for OTUs such as bicluster analyses, correlation coefficients and principal component analyses, the clear difference of this Data mining technique was that it set aside most OTUs and emphasized only some closely related ones. For example for a selected characteristic, such as smoking habit, only 7 OTUs out of 120 were able to identify all smokers, and the remaining 113 OTUs were thought of as data noise for smoking. Data mining analyses were affirmed as an effective method of subject discrimination for various physiological constitutions. The species of bacteria that were closely related to heavy smokers, i.e., HaeIII-291, were also discussed.

Published
2012

2. Surplus dietary tryptophan inhibits stress hormone kinetics and induces insulin resistance in pigs

Author

Mechiel Korte, Marko Ruis, Ruud Dekker, and Sietse Jan Koopmans

Subjects
Blood Glucose, medicine.medical_specialty, Epinephrine, Hydrocortisone, Nitrogen, Swine, medicine.medical_treatment, Dopamine, plasma-cortisol, Protein metabolism, Experimental and Cognitive Psychology, Carbohydrate metabolism, Biology, Excretion, Behavioral Neuroscience, chemistry.chemical_compound, Norepinephrine, Insulin resistance, Catecholamines, Internal medicine, axis, medicine, Animals, Amino Acids, glucose, Saliva, Pancreatic hormone, Dose-Response Relationship, Drug, glucocorticoids, Insulin, Tryptophan, protein-synthesis, medicine.disease, sensitivity, amino-acid utilization, serotonin, identical meals, Protein catabolism, Endocrinology, Amino Acids, Neutral, chemistry, Dietary Supplements, Glucose Clamp Technique, Insulin Resistance, Wageningen Livestock Research, skeletal-muscles
Abstract

Recently we have shown that surplus dietary tryptophan (TRP) reduced the plasma concentrations of cortisol and noradrenaline in pigs. Stress hormones are known to affect insulin sensitivity and metabolism. We now investigated the long-term effects of surplus dietary TRP on 1) plasma and urinary stress hormone kinetics, 2) insulin sensitivity for glucose and amino acid clearance, and 3) whole body nitrogen balance. Pigs were fed for 3 weeks a high (13.2%) vs normal (3.4%) TRP to large neutral amino acids (LNAA) diet, leading to reduced fasting (14 h) plasma cortisol (17.1 ± 3.0 vs 28.9 ± 4.3 ng/mL, p

Published
2009

3. Identification of Human Intestinal Microbiota of 92 Men by Data Mining for 5 Characteristics, i.e., Age, BMI, Smoking Habit, Cessation Period of Previous Smokers and Drinking Habit.

Author

Kobayashi T, Jin JS, Kibe R, Touyama M, Tanaka Y, Benno Y, Fujiwara K, Shimakawa M, Maruo T, Toda T, Matsuda I, Tagami H, Matsumoto M, Seo G, Sato N, Chounan O, and Benno Y

Abstract

The intestinal microbiota compositions of 92 men living in Japan were identified following consumption of identical meals for 3 days. Fecal samples were analyzed by terminal restriction fragment length polymorphism with 4 primer-restriction enzyme systems, and the 120 obtained operational taxonomic units (OTUs) were analyzed by Data mining software focusing on the following 5 characteristics, namely, age, body mass index, present smoking habit, cessation period of previous smokers and drinking habit, according to the answers of the subjects. After performing Data mining analyses with each characteristic, the details of the constructed Decision trees precisely identified the subjects or discriminated them into various suitable groups. Through the pathways to reach the groups, practical roles of the related OTUs and their quantities were clearly recognized. Compared with the other identification methods for OTUs such as bicluster analyses, correlation coefficients and principal component analyses, the clear difference of this Data mining technique was that it set aside most OTUs and emphasized only some closely related ones. For example for a selected characteristic, such as smoking habit, only 7 OTUs out of 120 were able to identify all smokers, and the remaining 113 OTUs were thought of as data noise for smoking. Data mining analyses were affirmed as an effective method of subject discrimination for various physiological constitutions. The species of bacteria that were closely related to heavy smokers, i.e., HaeIII-291, were also discussed.

Published
2013
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