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In recent years, nanoscience and nanotechnology have gained prominence within materials science, offering new opportunities for cancer diagnosis and treatment. Advances in nanotechnology have allowed for the manipulation and size control of nanomaterials, leading to the development of a wide range of materials. The use of nanomaterials as chemical biology tools in cancer theranostics has been widely investigated, owing to their enhanced stability, biocompatibility, and improved cell permeability. These properties enable precise targeting while addressing the limitations of conventional cancer treatments. Nanoflowers, a specific class of nanomaterials, have recently attracted significant interest due to their promising properties for several biomedical applications. However, despite the growing attention toward nanoflowers, detailed reviews on the subject have been limited. This work focuses on two primary types of hybrid nanoflowers: iron- and copper-based ones. Within this article an overview of recent applications in cancer theranostics are thoroughly reviewed, while the synthesis processes for controlling morphology and size, underlying functions, and their characteristics and uses are also extensively explored, aiming to provide a guide for future developments in the field. [ABSTRACT FROM AUTHOR]

[Display omitted] The present paper reports the fabrication of novel types of hybrid fibrous photocatalysts by combining block copolymer (BCP) templating, sol–gel processing, and coaxial electrospinning techniques. Coaxial electrospinning produces core–shell nanofibers (NFs), which are converted into hollow porous TiO 2 NFs using an oxidative calcination step. Hybrid BCP micelles comprising a single plasmonic nanoparticle (NP) in their core and thereof derived silica-coated core–shell particles are utilized as precursors to generate yolk-shell type particulate inclusions in photocatalytically active NFs. The catalytic and photocatalytic activity of calcined NFs comprising different types of yolk-shell particles is systematically investigated and compared. Interestingly, calcined NFs comprising silica-coated yolk-shells demonstrate enhanced catalytic and photocatalytic performance despite the presence of silica shell separating plasmonic NP from the TiO 2 matrix. Electromagnetic simulations indicate that this enhancement is caused by a localized surface plasmon resonance and a confinement effect in silica-coated yolk-shells embedded in porous TiO 2 NFs. Utilization of the coaxially electrospun TiO 2 NFs in combination with yolk-shells comprising plasmonic NPs reveals to be a potent method for the photocatalytic decomposition of numerous pollutants. It is worth noting that this study stands as the first occurrence of combining yolk-shells (Au@void@SiO 2) with porous electrospun NFs (TiO 2) for photocatalytic purposes and gaining an understanding of plasmon and confinement effects for photocatalytic performance. This approach represents a promising route for fabricating highly active and up-scalable fibrous photocatalytic systems. [ABSTRACT FROM AUTHOR]

Silicon, carbon and oxygen hybrid nanomaterials (i.e., SiCOHNs) have recently drawn extensive attention as versatile photoluminescence (PL) nanosystems. The collective advantages of silicon‐ and carbon‐based nanostructures have resulted in SiCOHNs with tunable and photostable PL properties, abundant possibilities for surface modification, and low biotoxicity. Although SiCOHNs have shown great potential in diverse applications, such as bioimaging, biosensing, drug delivery and information encryption, discovering novel SiCOHNs with explicit nanostructures and elucidating the fundamental mechanisms of their PL properties for bioapplications are highly desirable. In this review, on the preparation of SiCOHNs on the basis of the synthesis conditions and precursors are first focused. Next, the manipulation of the emission wavelength, quantum yield and RTP of SiCOHNs is discussed. On the basis of previous reports and the recent experimental/theoretical results, the primary structure of SiCOHNs is clarified and deduced their possible PL mechanism. SiCOHNs possess bacterial uptake efficiency and/or anticancer capacity, promoting various biomedical applications and proof‐of‐concept applications in anti‐counterfeiting. Finally, current challenges and future trends are summarized as a roadmap for the development of SiCOHNs‐based optical applications. [ABSTRACT FROM AUTHOR]

Chemical sensors, relying on changes in the electrical conductance of a gas-sensitive material due to the surrounding gas, typically react with multiple target gases and the resulting response is not specific for a certain analyte species. The purpose of this study was the development of a multi-sensor platform for systematic screening of gas-sensitive nanomaterials. We have developed a specific Si-based platform chip, which integrates a total of 16 sensor structures. Along with a newly developed measurement setup, this multi-sensor platform enables simultaneous performance characterization of up to 16 different sensor materials in parallel in an automated gas measurement setup. In this study, we chose the well-established ultrathin SnO2 films as base material. In order to screen the sensor performance towards type and areal density of nanoparticles on the SnO2 films, the films are functionalized by ESJET printing Au-, NiPt-, and Pd-nanoparticle solutions with five different concentrations. The functionalized sensors have been tested toward the target gases: carbon monoxide and a specific hydrogen carbon gas mixture of acetylene, ethane, ethne, and propene. The measurements have been performed in three different humidity conditions (25%, 50% and 75% r.h.). We have found that all investigated types of NPs (except Pd) increase the responses of the sensors towards CO and HCmix and reach a maximum for an NP type specific concentration. [ABSTRACT FROM AUTHOR]

Chemiresistive sensing lies in its ability to provide fast, accurate, and reliable detection of various gases in a cost‐effective and non‐invasive manner. In this context, graphene‐functionalized metal oxides play crucial role in hydrogen gas sensing. However, a cost‐effective, defect‐free, and large production schemes of graphene‐based sensors are required for industrial applications. This review focuses on graphene‐functionalized metal oxide nanostructures designed for gaseous molecules detection, mainly hydrogen gas sensing applications. For the convenience of the reader and to understand the role of graphene‐metal oxide hybrids (GMOH) in gas sensing activities, a brief overview of the properties and synthesis routes of graphene and GMOH have been reported in this paper. Metal oxides play an essential role in the GMOH construct for hydrogen gas sensing. Therefore, various metal oxides‐decorated GMOH constructs are detailed in this review as gas sensing platforms, particularly for hydrogen detection. Finally, specific directions for future research works and challenges ahead in designing highly selective and sensitive hydrogen gas sensors have been highlighted. As illustrated in this review, understanding of the metal oxides‐decorated GMOH constructs is expected to guide ones in developing emerging hybrid nanomaterials that are suitable for hydrogen gas sensing applications. [ABSTRACT FROM AUTHOR]

In this paper, the improvement of mechanical and thermal characteristics in nanocomposites with addition of CNTs is studied. As a result of CNTs structure and characteristics, the tensile strength, elasticity, toughness as well as thermal conductivity of CNT-reinforced nanocomposites are enhanced. This section presents key issues related to the CNTs such as dispersion, agglomeration, and cost together with the state-of-art of manufacturing procedure. Real-world applications for aerospace and electronics sectors plus energy storage are described and prospects for future research are outlined. Based on this study, nanocomposites of CNT are believed to have unprecedented opportunities for delivering value add for advanced material needs in today's high-stakes industries. [ABSTRACT FROM AUTHOR]

AbstractThis study investigates the fluid flow and heat transfer characteristics influenced by the thermophysical properties of carbon nanotube suspension in engine oil over a stretching-spiraling disk. The surface comprises Homan stagnation point flow impinging normal to a rotating, radially stretching disk, which gives velocity a form of logarithmic spiral. Similarity ansatz transformed coupled nonlinear differential equation system is derived and solved numerically using MATLAB’s bvp4c collocation method. Numerical and asymptotic solutions are also obtained against the controlled parameters via graphical representations and tabular data. Findings indicate that the magnetic field enhances temperature distribution while reducing the velocity field. At the same time, stretching increases radial velocity but decreases azimuthal velocity and temperature profiles, regardless of carbon nanotube type. The asymptotic values of skin friction decline with an increase in the spiralisng angle and in the absence of a magnetic field for both SWCNTs and MWCNTs cases. [ABSTRACT FROM AUTHOR]

This study examines the entropy generation and heat transfer performance in a Jeffrey-Hamel flow of biviscosity Bingham fluid with the addition of Al2O3 and Cu nanomaterials in the presence of a thermal Marangoni convective process. An emerging Jeffrey-Hamel problem is extended with the implementation of the Bingham fluid stress tensor in a Naiver Stokes equation. The governing equations with Marangoni boundary conditions due to surface tension are solved computationally utilizing the Keller-Box methodology. The findings demonstrate the complex interplay of entropy production processes, fluid-solid interfaces, and thermal Marangoni convection. Findings demonstrated that increasing Marangoni, Bingham parameters, and thermal radiation enhances the rate of heat transmission. The influence of the Marangoni and Bingham parameters on skin friction is conflicting in a narrow channel. System entropy and flow field uplift with a higher Marangoni convection parameter. Increasing the Reynolds number significantly increases the drag force, whereas the effect of the magnetic variable is the reverse. Velocity is an increasing function of the Reynolds and Bingham parameters and deteriorates with the load of nanomaterials. Temperature is a rising function of nanomaterial load, Eckert, and Bingham parameter. The results of this investigation have important ramifications for improving heat transfer, coolant systems, and nozzles design.

In recent years, nanoscience and nanotechnology have gained prominence within materials science, offering new opportunities for cancer diagnosis and treatment. Advances in nanotechnology have allowed for the manipulation and size control of nanomaterials, leading to the development of a wide range of materials. The use of nanomaterials as chemical biology tools in cancer theranostics has been widely investigated, owing to their enhanced stability, biocompatibility, and improved cell permeability. These properties enable precise targeting while addressing the limitations of conventional cancer treatments. Nanoflowers, a specific class of nanomaterials, have recently attracted significant interest due to their promising properties for several biomedical applications. However, despite the growing attention toward nanoflowers, detailed reviews on the subject have been limited. This work focuses on two primary types of hybrid nanoflowers: iron- and copper-based ones. Within this article an overview of recent applications in cancer theranostics are thoroughly reviewed, while the synthesis processes for controlling morphology and size, underlying functions, and their characteristics and uses are also extensively explored, aiming to provide a guide for future developments in the field.

Cellulosic aerogels are sustainable, biodegradable, and ultra-light porous materials with three-dimensional networks having high specific surface area. Depending on the source of precursor materials, they are categorized into plant-based aerogel, bacterial cellulosic aerogel. Different types of aerogels are also produced from microcrystalline cellulose (MCC), nanocrystalline cellulose (NCC), cellulose microfibril (CMF) and cellulose nanofibril (CNF). Furthermore, inorganic and organic substances are embedded to produce hybrid aerogel or composite aerogel for the enhancement of its performance in various fields. Mixing, gelation, solvent exchange, and drying (e.g., super critical carbon dioxide or freeze drying) are the basic steps involved in cellulosic aerogel synthesis. Based on the composition of precursors during aerogel synthesis, cellulosic aerogels have broad applications in various fields such as adsorbents, electrodes, sensors, captive deionization materials, catalysts, drug delivery, thermal and sound insulating materials. This review provided consolidated information on: (i) classification of cellulosic aerogels based on the sources of raw materials, (ii) processes involved to produce the cellulosic aerogel, (iii) cellulosic aerogel synthesized from MCC, NCC, CMF and CNF, (iv) nano particle doped cellulosic aerogel, and (v) its application in various field with future perspectives. [ABSTRACT FROM AUTHOR]

Objective here is to address impacts of MHD hybrid nanofluids (Fe2O3+Cu/H2O) on peristaltic transport in asymmetric channel. Porous space is taken. Analysis is constructed in the presence of radiation, dissipation, convection and Hall current. Further velocity and thermal slip boundary constraints are considered. Lubrication approach is employed to simplify the dimensionless forms of equations. Quantities of interest are described numerically. The shooting method is used to solve the governing differential systems employing Mathematica. Outcomes of Hartman number, Hall effect, permeability parameter, Grashof number and radiation parameter are analyzed graphically. Result indicates that temperature decreases by increasing the strength of nanomaterials. Axial velocity decays in the presence of Hartman number. Analysis of heat transport process is evaluated using tabulated values. Results show that heat process improved for Hartman number while the opposite behavior observed for Hall current.

Chitosan-encapsulated ternary titanium dioxide-nickel oxide-copper oxide (CTNC) hybrid nanomaterials (HNM) were synthesised via a facile one-pot precipitation method. The synthesised chitosan-titanium dioxide-nickel oxide-copper oxide was characterised by XRD, UV, FTIR, DLS, FESEM, EDAX, and PL tested against G− (gram-negative) bacterial strains such as K. pneumonia, S. dysenteriae, E. coli, P. vulgaris, P. aeruginosa, and V. cholerae, employed by the well method. The CTNC hybrid nanomaterials exhibit a more substantial antibacterial effect against gram-negative bacteria. The MDA-MB-231 cell-line with an IC50 concentration value of 9.8 g/mL was chosen to test CTNC hybrid nanomaterials' anticancer properties against human breast cancer cell lines. The toxicity studies of fibroblast L929 cells showed that the CTNC hybrid nanomaterials were less harmful to healthy cells. As a result, the CTNC hybrid nanomaterials can be used for biomedical and industrial applications to improve human health conditions. [ABSTRACT FROM AUTHOR]

An electrochemical biosensor for the bisphenol A determination was constructed onto a glassy carbon electrode modified with a hybrid nanostructure based on polypyrrole‐3‐carboxylic acid/Sb2O5/reduced graphene oxide and laccase enzyme. The hybrid nanostructure was characterized by X‐ray photoelectron spectroscopy (XPS), HR‐TEM, SEM microscopy, and electrochemical techniques. The biosensor displayed excellent response for bisphenol A determinations by differential pulse voltammetry, showing a theoretical detection limit of 9.9 nmol L−1 in the linear range of 0.1–1.0 μmol L−1. The biosensor demonstrated excellent selectivity in the determinations of bisphenol A in tap water without significant interference from other species, such as 17β‐estradiol, Estriol, Progesterone, Catechol, Hydroquinone, Ascorbic acid, and Dopamine. The biosensor also has presented an excellent performance in bisphenol A determinations in water, with recovery tax ranging from 99.6 to 101 %. Therefore, it can be used satisfactorily to detect bisphenol A in real samples. [ABSTRACT FROM AUTHOR]

In this work, we report the application of Au/WO3 composite as a photocatalyst for the degradation of dyes under solar light irradiation. Au/WO3 nanocomposites were synthesized using an acid precipitation method followed by an impregnation/reduction at room temperature. Two composites were obtained by loading gold nanoparticles on two morphologies of nanostructured WO3, nanoplatelets (NP), and pseudospheres (PS). The elaboration parameters of the nanocomposites were optimized according to the gold mass percentage, the HAuCl4 precursor concentration, and the impregnation time. The structural, microstructural, and textural characterization were conducted using advanced techniques: XRD, SEM/TEM microscopies, and XPS and DRS spectroscopies. The optimal synthesis parameters are a 48 h impregnation of a five mass percentage of gold from a HAuCl4 precursor with a concentration of 10−3 mol·L−1. The obtained composites were formed with Au nanoparticles of 7 nm in size. The XRD analyses did not reveal any modification of the oxide supports structure after gold grafting, contrary to the sorption analyses, which evidenced a change in the state of the materials surface. XPS analysis revealed the reduction of W6+ ions into W5+, favoring the presence of oxygen vacancies. Furthermore, a localized surface plasmon resonance effect was observed in the composite at 540 nm. The photocatalysis results of several dye pollutants have shown a selective degradation efficiency depending on the charge of the polluting molecules, pH medium, and mass loading of the catalysts. At the native pH, the photocatalysis process is highly efficient on a cationic molecule, with a low adsorption capacity. Au/WO3 PS composite appears to be the most efficient, degrading almost the whole RhB and MB only in 60 min and 90 min, respectively, while, for the MO anionic dye, the degradation is more efficient in acidic medium (80%) than in basic medium (0%). Trap tests of the main active species were investigated and a photodecomposition mechanism is proposed. [ABSTRACT FROM AUTHOR]

Objective here is to address impacts of MHD hybrid nanofluids (Fe 2 O 3 + Cu / H 2 O) on peristaltic transport in asymmetric channel. Porous space is taken. Analysis is constructed in the presence of radiation, dissipation, convection and Hall current. Further velocity and thermal slip boundary constraints are considered. Lubrication approach is employed to simplify the dimensionless forms of equations. Quantities of interest are described numerically. The shooting method is used to solve the governing differential systems employing Mathematica. Outcomes of Hartman number, Hall effect, permeability parameter, Grashof number and radiation parameter are analyzed graphically. Result indicates that temperature decreases by increasing the strength of nanomaterials. Axial velocity decays in the presence of Hartman number. Analysis of heat transport process is evaluated using tabulated values. Results show that heat process improved for Hartman number while the opposite behavior observed for Hall current. [ABSTRACT FROM AUTHOR]

The intersection between the field of hybrid materials and that of electrochemistry is a quickly expanding area. Hybrid combinations usually consist of two constituents, but new routes toward more complex and versatile electroactive hybrid designs are quickly emerging. The objective of the present work is to explore novel triple hybrid material integrating polyoxometalates (POMs), silver nanoparticles (Ag0 NPs), and activated carbon (AC) and to demonstrate its use as a hybrid electrode in a symmetric supercapacitor. The tri-component nanohybrid (AC/POM-Ag0 NPs) was fabricated through the combination of AC with pre-synthesized ∼27 nm POM-protected Ag0 NPs (POM-Ag0 NPs). The POM-Ag0 NPs were prepared using a green electrochemical method and characterized via UV-vis and IR spectroscopy, electron microscopy, dynamic light scattering (DLS), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and cyclic voltammetry (CV). Afterward, the AC/POM-Ag0 NPs ternary nanocomposite material was constructed and characterized. The electrochemical behavior of AC/POM-Ag0 NPs' modified electrodes reveal that the nanomaterial is electroactive and exhibits a moderately higher specific capacitance (81 F/g after 20 cycles) than bare AC electrodes (75 F/g) in a symmetrical supercapacitor configuration in the voltage range 0 to 0.75 V and 20 mV/s, demonstrating the potential use of this type of tri-component nanohybrid for electrochemical applications. [ABSTRACT FROM AUTHOR]

This paper studies the mechanical behavior of functionally graded material viscoelastic (FGVE) products employed in automotive, chemical industry, and biomedical appliances. Various experimental models describe and simulate nanobeams with viscoelastic layers subjected to tensile loading, 3-point bending, tear, and impact. All specimens were prepared using the 3D printing method. Tensile, hardness, tear, impact, and bending specimens reinforced with different volume fractions (1-5)% of Al2O3, TiO2, and a hybrid of the nanomaterials Al2O3 /TiO2 were arranged via a mixing process with an extruder and then fabricated by a 3D printing machine. The experimental results of maximum bending load, midspan deflection, impact, and tear resistance were validated by finite element methods (FEM) with the assistance of commercial software (Ansys Workbench 2021 R1). Furthermore, the influence of various parameters on the mechanical performance of reinforced samples has been thoroughly investigated, for example, volume fraction index, nanoparticles content, and FG properties. Based on the findings, the most successful results were obtained by adding 1.5 % Al2O3 and 3% TiO2 hybrid nanoparticles. The experimental and numerical results were in reasonable agreement. The discrepancy did not exceed 10.25% for maximum bending load and no difference over 5% for maximum impact load, indicating that the strengthened nanoparticle specimens were properly fabricated. Also, a significant improvement in mechanical and viscoelastic properties was achieved by incorporating hybrid nanoparticles. Flexural bending load increased by about 17 % with hybrid nanoparticles, while tear resistance increased by 27.5 % and impact resistance increased by 7.5%.

The ability to sense and stimulate cellular and tissue electrophysiology is fundamental to input/output bioelectronics. Their functionality is primarily governed by the structural and functional properties of the constituent electrode materials. Conventional electrode materials are hindered by their two-dimensional topology, high electrochemical impedances, low charge injection capacities, and limited stability over chronic timescales. Here, we propose a strategy for obtaining high-surface-area hybrid-nanomaterial for efficient I/O bioelectronics by conformally templating conductive polymer poly-(3,4-ethylenedioxythiophene)–polystyrene sulfonate (PEDOT:PSS) onto nanowire-templated three-dimensional (3D) fuzzy graphene (NT-3DFG). The result is a high-performance electrode material that can leverage the exceptional surface area of NT-3DFG and the volumetric charge storage properties of PEDOT:PSS. Owing to its high surface area, NT-3DFG microelectrodes exhibit lower electrode impedance and up to 35-fold greater charge injection capacity (CIC) compared to conventional metal microelectrodes. Conformally templating PEDOT:PSS onto NT-3DFG further reduces electrode impedance and enhances CIC by 125-fold compared to conventional metal microelectrodes. Moreover, the NT-3DFG-based nanomaterials exhibit high functional stability. Our results highlight the importance of extrapolating electrode topography to 3D and developing hybrid nanomaterials for miniaturized microelectrodes for functional bioelectronics. [ABSTRACT FROM AUTHOR]

Herein, we proposed and demonstrated a facile and scalable strategy to fabricate multifunctional self-similar superhydrophobic coatings. Firstly, a hydrophobic cationic cellulose derivative containing imidazolium cation was synthesized by a controllable derivatization. It could effectively disperse one-dimensional (1D) multi-walled carbon nanotubes (MWCNT), because the imidazolium cations formed cation—π interactions with MWCNT. Further, the synergy effect of the cationic cellulose derivative and MWCNT dispersed two-dimensional (2D) reduced graphene oxide (rGO) to obtain a three-components nano-dispersion. Finally, via a simple spaying process, a superhydrophobic coating with self-similar micro-nano structures spontaneously formed from inside to outside, owing to the various nanostructures with different shapes and sizes in the dispersion and the adhesive effect of the cellulose derivative. This superhydrophobic coating was easy to scale, and exhibited superior stability owing to the renewal micro-nano structures. It retained the superhydrophobicity even if it was treated by rubbing for 1500 times. Moreover, it had outstanding photo-thermal and Joule-heating performance, because of the strong solar absorption and high electrical conductivity of MWCNT and rGO. It provided both passive anti-icing and active deicing effects. Thus, it could achieve all-weather anti-icing for wind power generators under sunlight and low voltage conditions. Such facile preparation method and multifunctional renewable superhydrophobic coating hold great application prospects. [ABSTRACT FROM AUTHOR]

Given their relevance in various physiological and pathophysiological mechanisms, gaseous signaling molecules (GSMs), such as nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S), are promising therapeutics for derailing various diseases at precisely controlled concentrations. However, the delivery and release of GSMs have been challenged by the heterogeneity of biological systems. Carefully constructed hybrid materials have exhibited enhanced functional ability owing to the adjusted individual characteristics. In this minireview, we surveyed the mechanisms of gas therapy, recent exceptional studies on the controlled release of GSMs from hybrid nanoplatforms, and their applications in the treatment of various diseases. Single gas therapies and their combined modalities with conventional treatments such as chemotherapy, photodynamic therapy (PDT), photothermal therapy (PTT), and immunotherapy have been summarized, with critical analysis of the contribution of the metallic elements in the various nanoplatforms. Moreover, the challenges and prospects of hybrid GSM releasers as promising healings have been discussed.

Magnetic nanoparticles surrounded with a silica shell are useful materials to immobilize active agents on their surface. Here, a heteropolyacid-functionalized hybrid nanomaterial (NiFe2O4@SiO2-DETA@POM) was prepared and characterized by X-ray powder diffraction patterns (XRD), Fourier-transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA/DTG), vibrating sample magnetometer (VSM), the field emission scanning electron microscopy (FE-SEM), and the electron-dispersive X-ray spectroscopy (EDS). The synthesized hybrid nanostructure was used as a solid nanocatalyst in oxidative desulfurization (ODS) of real fuel and simulated gasoline samples. The ODS process of benzothiophene (BT) and dibenzothiophene (DBT) as model compounds in the presence of NiFe2O4@SiO2-DETA@POM and by using urea-hydrogen peroxide/acetic acid as a safer oxidizing agent was investigated. A good result was obtained by removing 97% of benzothiophene and 98% of dibenzothiophene. Also, 96% of the sulfur compounds were eliminated when the ODS process was tested on a real crude oil sample (600 ppm) under an optimized dosage of nanocatalyst, urea-hydrogen peroxide/acetic acid (0.1 g, 1 g/4 ml) at 50 ºC for 60 min. NiFe2O4@SiO2-DETA@POM could be recycled for five consecutive oxidation runs without significant deterioration in its catalytic activity. The UHP's safety and efficiency as an oxidant, high removal efficacy, short transformation times, easy workup procedure, catalyst reusability, simple separation of nanocatalyst, green conditions, and environmental compatibility and sustainability. The obtained results prove that NiFe2O4@SiO2-DETA@POM is a suitable and efficient hybrid catalyst for the oxidative desulfurization of simulated and real fuels. [ABSTRACT FROM AUTHOR]

Nature inspired biomimetic growth of anisotropic, hierarchical nanostructures could offer insight into new and exciting crystalline properties for advanced multifunctional applications. Our study demonstrates diethanolamine-mediated mesoscopic self-assembly of semiconducting ZnO Quantum Dots (3–5 nm) into lattice-aligned, symmetrical superstructures (40–50 nm) via non-classical oriented attachment (OA) crystal growth observed in various biomineralization processes. Multifunctional nanocomposite thin films of self-assembled nanostructures and polymethyl methacrylate were spin-coated onto plasma-treated Si wafers and the surface and interfacial properties were rigorously studied. HR-TEM images depicted the OA growth process with neighboring nano-crystals having perfectly aligned lattices. Preferential orientation of the thin films along <100> direction was evident from the XRD data. Quantum confinement in ZnO QDs and surface defect originating sharp green PL emission were examined through UV–Vis absorption and Photoluminescence spectra respectively. DLS and Zeta potential studies of surface-engineered colloidal superstructures established excellent long-term physico–chemical stability with no agglomeration or transparency loss observed in ZnO mesocrystal suspension even after 6 months. Diethanolamine, due to its dual functionality radically enhanced the interaction between polar ZnO and non-polar PMMA matrix resulting in highly stable thin films (Class II hybrids) with enhanced surface and interfacial properties as evident from the extremely low surface roughness and homogenous nanofiller dispersion observed in AFM and FE-SEM studies. Chemical interactions at the interface were also established quantitatively by XPS binding energy measurements which suggested hydrogen bonds and covalent bonds between organic-inorganic phases promoted via diethanolamine surface engineering. [ABSTRACT FROM AUTHOR]

Nano‐immunotherapy has been recognized as a highly promising strategy for cancer treatment in recent decades, which combines nanotechnology and immunotherapy to combat against tumors. Hybrid nanomaterials consisting of at least two constituents with distinct compositions and properties, usually organic and inorganic, have been engineered with integrated functions and enormous potential in boosting cancer immunotherapy. This review provides a summary of hybrid nanomaterials reported for cancer immunotherapy, including nanoscale metal–organic frameworks, metal–phenolic networks, mesoporous organosilica nanoparticles, metallofullerene nanomaterials, polymer–lipid, and biomacromolecule‐based hybrid nanomaterials. The combination of immunotherapy with chemotherapy, chemodynamic therapy, radiotherapy, radiodynamic therapy, photothermal therapy, photodynamic therapy, and sonodynamic therapy based on hybrid nanomaterials is also discussed. Finally, the current challenges and the prospects for designing hybrid nanomaterials and their application in cancer immunotherapy are outlined. [ABSTRACT FROM AUTHOR]

Plasmonic nanostructures have attracted a broad research interest due to their application perspectives in various fields such as biosensing, catalysis, photovoltaics, and biomedicine. Their synthesis by pulsed laser ablation in pure water enables eliminating various side effects originating from chemical contamination. Another advantage of pulsed laser ablation in liquids (PLAL) is the possibility to controllably produce plasmonic nanoparticles (NPs) in combination with other plasmonic or magnetic materials, thus enhancing their functionality. However, the PLAL technique is still challenging in respect of merging metallic and semiconductor specific features in nanosized objects that could significantly broaden application areas of plasmonic nanostructures. In this work, we performed synthesis of hybrid AuSi NPs with novel modalities by ultrashort laser ablation of bulk gold in water containing silicon NPs. The Au/Si atomic ratio in the nanohybrids was finely varied from 0.5 to 3.5 when changing the initial Si NPs concentration in water from 70 µg/mL to 10 µg/mL, respectively, without requiring any complex chemical procedures. It has been found that the laser-fluence-insensitive silicon content depends on the mass of nanohybrids. A high concentration of paramagnetic defects (2.2·× 1018 spin/g) in polycrystalline plasmonic NPs has been achieved. Our findings can open further prospects for plasmonic nanostructures as contrast agents in optical and magnetic resonance imaging techniques, biosensing, and cancer theranostics. [ABSTRACT FROM AUTHOR]

Oxidants are very active compounds that can cause damage to biological systems under specific environmental conditions. One effective way to counterbalance these adverse effects is the use of anti-oxidants. At low concentrations, an antioxidant is defined as a compound that can delay, control, or prevent an oxidative process. Antioxidants exist in plants, soil, and minerals; therefore, nature is a rich source of natural antioxidants, such as tocopherols and polyphenols. In nature, antioxidants perform in tandem with their bio-environment, which may tune their activity and protect them from degradation. In vitro use of antioxidants, i.e., out of their biomatrix, may encounter several drawbacks, such as auto-oxidation and polymerization. Artificial nanoantioxidants can be developed via surface modification of a nanoparticle with an antioxidant that can be either natural or synthetic, directly mimicking a natural antioxidant system. In this direction, state-of-the-art nanotechnology has been extensively incorporated to overcome inherent drawbacks encountered in vitro use of antioxidants, i.e., out of their biomatrix, and facilitate the production and use of antioxidants on a larger scale. Biomimetic nanoengineering has been adopted to optimize bio-medical antioxidant systems to improve stability, control release, enhance targeted administration, and overcome toxicity and biocompatibility issues. Focusing on biotechnological sciences, this review highlights the importance of nanoengineering in developing effective antioxidant structures and comparing the effectiveness of different nanoengineering methods. Additionally, this study gathers and clarifies the different antioxidant mechanisms reported in the literature and provides a clear picture of the existing evaluation methods, which can provide vital insights into bio-medical applications. [ABSTRACT FROM AUTHOR]

Abstract The development of chemo/photothermal nanotherapeutic systems with excellent photothermal performance, stable drug loading, tumor targeting and strong membrane penetration still remains a challenge. To address this problem, herein a rod-like nanocomposite system (AuNR@FA-PR/PEG) forming from folic acid (FA) terminated carboxylated cyclodextrin (CD) pseudopolyrotaxane (FA-PR) and polyethylene glycol (PEG) modifying gold nanorods (AuNR) was reported. Cisplatin (CDDP) was loaded in AuNR@FA-PR/PEG via coordination bonds to prepare a rod-like pH-responsive nanosystem (AuNR@FA-PR/PEG/CDDP) with chemotherapy/photothermal therapy. The rod-like morphology of AuNR@FA-PR/PEG was characterized by transmission electron microscope. In vitro drug release experiments showed the pH-responsive of AuNR@FA-PR/PEG/CDDP. In vivo real-time imaging assays proved AuNR@FA-PR/PEG/CDDP could rapidly enrich in the tumor area and stay for a long time because of folate targeting and their rod-like morphology. In vivo photothermal imaging assays showed AuNR@FA-PR/PEG/CDDP excellent photothermal performance, the average temperature of tumor region could reach 63.5 °C after 10 min irradiation. In vitro and in vivo experiments also demonstrated that the combined therapy of chemotherapy and photothermal therapy had an outstandingly synergistic effect and improved the therapeutic efficacy comparing with chemotherapy and photothermal therapy alone. Therefore, the prepared rod-like AuNR@FA-PR/PEG/CDDP will provide a new strategy for the effective treatment of cancer.

Lung cancer is one of the most common cancers, affecting more than 2.1 million people across the globe every year. A very high occurrence and mortality rate of lung cancer have prompted active research in this area with both conventional and novel forms of therapies including the use of nanomaterials based drug delivery agents. Specifically, the unique physico-chemical and biological properties of porous nanomaterials have gained significant momentum as drug delivery agents for delivering a combination of drugs or merging diagnosis with targeted therapy for cancer treatment. This review focuses on the emergence of nano-porous materials for drug delivery in lung cancer. The review analyses the currently used nanoporous materials, including inorganic, organic and hybrid porous materials for delivering drugs for various types of therapies, including chemo, radio and phototherapy. It also analyses the selected research on stimuli-responsive nanoporous materials for drug delivery in lung cancer before summarizing the various findings and projecting the future of emerging trends. This review provides a strong foundation for the current status of the research on nanoporous materials, their limitations and the potential for improving their design to overcome the unique challenges of delivering drugs for the treatment of lung cancer. [ABSTRACT FROM AUTHOR]

Climate change, critical material shortages and environmental degradation pose an existential threat to the entire world. Immediate action is needed to transform the global economy towards a more circular economy with less intensive use of fossil energy and limited resources and more use of recyclable materials. Recyclable materials and manufacturing techniques will play a critical role in this transformation. Substantial advancements will be needed to achieve a more intelligent materials design to enhance both functionality and enhanced sustainability. The development of hybrid materials combining functionality at macro and nano scales based on organic and inorganic compounds, that are entirely recyclable could be used for tremendous applications. In this mini-review, we provide the reader with recent innovations on hybrid materials for application in water, energy and raw materials sectors. The topic is very modern and after its deep study we propose a creation an international research centre, that would combine the development of hybrid materials with green manufacturing. We have highlighted a framework that would comprise critical themes of the initial research needed. Such a centre would promote sustainable production of materials through intelligent hybridisation and eco-efficient, digital manufacturing and enable a circular economy in the long term. Such activities are strongly supported by current environmental and economical initiatives, like the Green Deal, REPower EU and digital EU initiatives. [ABSTRACT FROM AUTHOR]

Bimetallic or alloyed nanoparticles (NPs) are important materials that often exhibit chemical properties different from those of their monometallic counterparts. However, access to uniformly alloyed bimetallic particles, particularly in the Pd–Rh system, is difficult because of the thermodynamic immiscibility of the individual metals. Herein, we propose a method for accumulating Pd–Rh alloy particles on the surface of zeolite imidazolide framework-67 (ZIF-67), a chemically stable metal–organic framework, under mild conditions at 25 °C. The degradation of methyl orange was used to test the applicability of the resultant material as a heterogeneous catalyst. A turnover frequency of 38.5 h–1 was recorded for Pd0.12Rh0.88/ZIF-67, which is higher than that of catalysts with either Pd (17.2 h–1) or Rh (16.5 h–1). The acceleration of methyl orange decomposition was attributed to electron transfer from Pd to Rh in the alloy particles due to the differences in Pauling electronegativity and an increase in metallic Rh on the catalyst surface. No metal leakage or structural degradation of the ZIF-67 support was observed during the catalytic reaction. Pd0.12Rh0.88/ZIF-67 could actively degrade methyl orange, Congo red, and methylene blue. The structure of the catalyst remained intact even when a mixed solution of all three dyes was circulated for 60 min in a fixed-bed system, and the catalyst conversion rate exceeded 99.7%. Our results collectively demonstrate the successful preparation of Pd–Rh-supported catalysts and their application to the continuous reduction of multicomponent dye mixtures. The metal NP-MOF composites prepared using the proposed approach are free from MOF pore damage and can maintain their specific surface area. Therefore, this strategy could give impetus to research on catalytic applications of NP-MOF composites. [ABSTRACT FROM AUTHOR]

Combination of dissimilar materials such as noble metals and common semiconductors within unified nanomaterials holds promise for optoelectronics, catalysis and optical sensing. Meanwhile, difficulty of obtaining such hybrid nanomaterials using common lithography-based techniques stimulates an active search for advanced, inexpensive, and straightforward fabrication methods. Here, we report one-pot one-step synthesis of Ag-decorated Si microspheres via nanosecond laser ablation of monocrystalline silicon in isopropanol containing AgNO3. Laser ablation of bulk silicon creates the suspension of the Si microspheres that host further preferential growth of Ag nanoclusters on their surface upon thermal-induced decomposition of AgNO3 species by subsequently incident laser pulses. The amount of the AgNO3 in the working solution controls the density, morphology, and arrangement of the Ag nanoclusters allowing them to achieve strong and uniform decoration of the Si microsphere surface. Such unique morphology makes Ag-decorated Si microspheres promising for molecular identification based on the surface-enhanced Raman scattering (SERS) effect. In particular, the designed single-particles sensing platform was shown to offer temperature-feedback modality as well as SERS signal enhancement up to 106, allowing reliable detection of the adsorbed molecules and tracing their plasmon-driven catalytic transformations. Considering the ability to control the decoration degree of Si microspheres by Ag nanoclusters via amount of the AgNO3, the developed one-pot easy-to-implement PLAL synthesis holds promise for gram-scale production of high-quality hybrid nanomaterial for various nanophotonics and sensing applications. [ABSTRACT FROM AUTHOR]

The nanoparticles are frequently used in biomedical science for the treatment of diseases like cancer and these nanoparticles are injected in blood which is transported in the cardiovascular system on the principle of peristalsis. This study elaborates the effects of Lorentz force and joule heating on the peristaltic flow of copper and iron oxide suspended blood based nanofluid in a complex wavy non-uniform curved channel. The Brinkman model is utilized for the temperature dependent viscosity and thermal conductivity. The problem is formulated using the fundamental laws in terms of coupled partial differential equations which are simplified using the creeping flow phenomenon. The graphical results for velocity, temperature, streamlines, and axial pressure are simulated numerically. The concluded observations deduce that the solid volume fraction of nanoparticles reduces the velocity and enhance the pressure gradient and accumulation of trapping bolus in the upper half of the curved channel is noticed for temperature dependent viscosity. [ABSTRACT FROM AUTHOR]

A double-layer structure coating combining the advantages of GO shielding and the conductivity of MWCNTs was proposed. The sol–gel method was used to prepare SiO2-GO and SiO2-MWCNTs hybrid materials and 1wt% zinc silicate (ZS) double-layer structure composite coating was prepared. Mechanical strength and electrochemistry were tested to compare the effects of added phase and structure on the properties of the coating. The results showed that among the single-layer coatings, the zinc silicate coating with SiO2-GO had the best surface properties, the hardness of the coating reached 6H, the impact strength reached 75 300 g·cm, the SiO2-GO/ZS coating had hydrophobic properties, and the contact angle reached 92°. MWCNTs/ZS coating had very high interfacial bonding strength, and the average adhesion was 8.02 MPa, which was about 3 times higher than that of ZS coating. In terms of corrosion resistance, the double-layer structural coating of MWCNTs/ZS undercoat and SiO2-GO/ZS topcoat had the minimum corrosion current density and maximum impedance, which were 1.732 μA/cm2 and 23KΩ/cm2 respectively and could still maintain excellent cathodic protection under long-term immersion. [ABSTRACT FROM AUTHOR]

Metal-organic frameworks (MOFs) have the advantages of tunable pore sizes and porosity and have demonstrated unique advantages for various applications. This study synthesized composite MOF nanomaterials by modifying MOF801 or AlOOH with UIO66. The composite nanomaterials, UIO66/MOF801 and UIO66/AlOOH showed increased Zeta potential than their pristine form, AlOOH, UIO66 and MOF801. For the first time, the composite MOFs were used to fabricate filter paper-based evaporation-driven power generators for spontaneous electricity generation. The MOFs-KBF membrane was constructed by coating filter paper (10 × 50 mm) with composite MOFs and conductive Ketjen Black. The UIO66/MOF801 decorated device achieved a maximum open circuit voltage of 0.329 ± 0.005 V and maximum output power of 2.253 μW. The influence of salt concentration (0.1–0.5 M) on power generation was also analyzed and discussed. Finally, as a proof-of-concept application, the device was employed as a salinity sensor to realize remote monitoring of salinity. This work demonstrated the potential of flexible MOF composites for spontaneous power generation from water evaporation and provides a potential way to enhance the performance of evaporation-driven power generators. [ABSTRACT FROM AUTHOR]

The generation and controlled or uncontrolled release of hydrocarbon-contaminated industrial wastewater effluents to water matrices are a major environmental concern. The contaminated water comes to surface in the form of stable emulsions, which sometimes require different techniques to mitigate or separate effectively. Both the crude emulsions and hydrocarbon-contaminated wastewater effluents contain suspended solids, oil/grease, organic matter, toxic elements, salts, and recalcitrant chemicals. Suitable treatment of crude oil emulsions has been one of the most important challenges due to the complex nature and the substantial amount of generated waste. Moreover, the recovery of oil from waste will help meet the increasing demand for oil and its derivatives. In this context, functional nanostructured materials with smart surfaces and switchable wettability properties have gained increasing attention because of their excellent performance in the separation of oil–water emulsions. Recent improvements in the design, composition, morphology, and fine-tuning of polymeric nanostructured materials have resulted in enhanced demulsification functionalities. Herein, we reviewed the environmental impacts of crude oil emulsions and hydrocarbon-contaminated wastewater effluents. Their effective treatments by smart polymeric nanostructured materials with wettability properties have been stated with suitable examples. The fundamental mechanisms underpinning the efficient separation of oil–water emulsions are discussed with suitable examples along with the future perspectives of smart materials.

Abstract Peptide molecule has high bioactivity, good biocompatibility, and excellent biodegradability. In addition, it has adjustable amino acid structure and sequence, which can be flexible designed and tailored to form supramolecular nano-assemblies with specific biomimicking, recognition, and targeting properties via molecular self-assembly. These unique properties of peptide nano-assemblies made it possible for utilizing them for biomedical and tissue engineering applications. In this review, we summarize recent progress on the motif design, self-assembly synthesis, and functional tailoring of peptide nano-assemblies for both cancer diagnosis and therapy. For this aim, firstly we demonstrate the methodologies on the synthesis of various functional pure and hybrid peptide nano-assemblies, by which the structural and functional tailoring of peptide nano-assemblies are introduced and discussed in detail. Secondly, we present the applications of peptide nano-assemblies for cancer diagnosis applications, including optical and magnetic imaging as well as biosensing of cancer cells. Thirdly, the design of peptide nano-assemblies for enzyme-mediated killing, chemo-therapy, photothermal therapy, and multi-therapy of cancer cells are introduced. Finally, the challenges and perspectives in this promising topic are discussed. This work will be useful for readers to understand the methodologies on peptide design and functional tailoring for highly effective, specific, and targeted diagnosis and therapy of cancers, and at the same time it will promote the development of cancer diagnosis and therapy by linking those knowledges in biological science, nanotechnology, biomedicine, tissue engineering, and analytical science.

All previously published data on the dynamics of ethylene glycol conveying copper and gold nanoparticles over a convective surface, nothing is known about the importance of dual branch solutions. Hybrid nanofluids improve the thermal conductivity of the fluid. The nanoparticles copper and gold having ethylene glycol as a base fluid are used here. The flow problem is described over a stretching/shrinking surface with the influence of Ohmic heating, non-linear radiation, and a convectively heated surface. Furthermore, the magnetic field strength is applied perpendicular to the direction of the flow. To control the fluid, flow-governing equations are numerically solved by using bvp4c, a built-in approach in MATLAB. For hybrid nanomaterials, the consequence of different physical parameters is discussed graphically and with tabular data. A comparison with previous findings reveals that the present findings are in good agreement. The results revealed that the coefficient of skin friction for the physically stable branch declines over a certain range of shrinking parameters; nonetheless, for the unstable branch, the reverse pattern is discovered. The magnetic force diminishes the flow field and energy dispersion in the upper branch but improves it in the lower branch.

• The special hybrid combination enabled the aerogel to be a pressure sensor with a wide detection range to monitor small and large movements, such as swallowing, pulse, finger bending, and elbow bending. • A human-computer interaction interface of an artificial hand was designed which was mainly used to detect the spatial pressure distribution of the hand in different motion states. • ΔV/V-RGB and ΔR/R 0 -Color scale are respectively designed to prove the feasibility of the aerogel being used in different design systems. • This work offers a promising path for preparing aerogel with wide pressure ranges in wearable electronics. Wearable pressure sensors with highly sensitive and wide detection ranges are essential for human motion monitoring. In this work, a self-assembled hybrid aerogel was obtained by polyacrylonitrile nanofibers, polyaniline, and reduced graphene oxide. Based on the complementation of 1D and 2D nanomaterials, the aerogel acted like a spring under lower pressure and a membrane under higher pressure, showing great potential in human motion monitoring. According to the wide detection range of the aerogel, an artificial hand was designed to recognize different spatial pressures such as grasping a pen, holding a bottle, and shaking hands. These signal outputs could be precisely reflected by voltage change and further converted to RGB values. Meanwhile, a shoe pad was prepared to monitor foot pressure and the resistance change could be converted to color scale signals. This work provides a new strategy for 1D/2D hybrid nanomaterials-based aerogel with wide pressure ranges in flexible electronics. [Display omitted] [ABSTRACT FROM AUTHOR]