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The use of modern electronic gadgets leads to high rates of work, better assimilation of knowledge and a high level of preparedness of students. Introduction in educational process of new e-learning-notebooks, tablets, e-readers require justifi cation of their safety for health of pupils, and the rapid modernization of electronic gadgets, the speed of these studies. The widespread use of information technology has potential negative consequences associated with Freestyle or unwitting violation or disregard of user’s safe modes that must be followed in the application. The purpose of the research was to study the infl uence of Tablet PC e-learning in secondary school on the functional state of the students. The study was conducted at the beginning and end of lessons using electronic tablets, and without them the 235 pupils of 7–8 classes. Analysis of the responses of the functional systems of the grade 7 students at diff erent school organization not only not improved the tiring eff ects of lessons on using electronic tablets, but also showed greater resistance to fatigue from them than the traditional classroom because of hygienic management of lessons in applying e-learning: the optimal change of activity, the density of 60–80% of the lessons, the total duration of the work with the Tablet for the lesson-no more than 15 minutes continuous / no more than 4 minutes. Training using electronic textbook for eighth graders proved more arduous than classes without Tablet PC: by the end of the lesson, have dropped the speed and accuracy of work, IHI mental performance declined in 3 times, 51% of students complete lessons with explicit and visible fatigue. The infl uence of electronic tablet on tedious functional state of class 8 students due to a variety of reasons (high intensity training with frequent change of training), features of adaptation of pupils not only to new technical means of teaching, but also to the new subject, technical diffi culties in the development of e-learning tools. For an objective judgement on the impact of electronic textbooks on the functional State of an organism students need longer (minimum school year) monitoring.

Numerous studies in experiments on laboratory animals and in clinical practice have confirmed the positive effect of essential phospholipids on the structural organization of cell membranes, intracellular metabolism, mitochondrial function, antioxidant processes, which explains the active use of phospholipid-containing drugs in hepato- and enteropathologies, cardiovascular diseases, etc. The raw material of animal origin, in particular milk, which is a safe source of biologically active substances, has a structural similarity with phospholipids of mammalian tissues. Based on them, a biologically active additive (BAA) "FLP-MD" was created, which is characterized by membranotropic properties and reparative effect. The aim of this work was to investigate the biological effect of the liposomal form of BAA "FLP-MD" based on milk phospholipids on the body of clinically healthy laboratory mice. Determination of the toxicity of phospholipid-containing BAA "FLP-MD" was performed on mice of the CBA line. The duration of the experiment was 16 days. The results of the studies indicate a probable increase in body weight of mice of the CBA line aŌer the 10th day of intragastric administration of 1% solution of liposomal form of BAA "FLP-MD". As a result of the study of biochemical parameters of plasma / native blood, the absence of toxic effects of the liposomal form of BAA "FLP-MD" on the functional state of the body of mice was set. Morphological parameters of peripheral blood in these animals did not change significantly. According to the results of microscopic studies, no negative effect of the liposomal form of BAA "FLP-MD" on the structure microstructure of the mucous membrane of the gastrointestinal tract was found. Therefore, the components of BAA "FLP-MD" do not adversely affect the functional state of organs and systems of laboratory mice and do not show a toxic effect, which allows it to be recommended for use in veterinary medicine as a means of rehabilitation therapy

Background. The relationship between the T786C polymorphism of the eNOS gene and functional state of the body is not well understood. Objective. To establish the associations between the T786C polymorphism and the functional state of the organism. Material and methods. The study participants were healthy male volunteers (n = 117). A polymorphic variant of the eNOS gene was determined at the T786C locus. The physical and functional state of the body was evaluated. The results were processed using generally accepted statistical methods. Results. In individuals with the TT genotype diastolic pressure was 4.2% and 5.2% lower compared to the TC and CC genotypes, respectively. The mean dynamic pressure with the TT genotype was 2.7% and 3.1% less than with the TC and CC genotypes. Peripheral vascular resistance in individuals with a dominant genotype was 14.7% lower than in those with a recessive one. The values of the Cerdo index and cardiac index in individuals with C allele were statistically significantly lower compared with the subjects with the TT genotype. Conclusion. The association between the T786C polymorphism and the functional state of the organism was revealed. It seems appropriate to study the formation of oxygen-dependent processes taking into account the above polymorphism.

Objectives: For the timely detection of the people's health problems in the Arctic zone we used in parallel methods of heart rhythm variability (HRV) and gas-discharge visualization (GDV). Subjects: A group of 120 volunteers - male residents of Murmansk region in Russia's Arctic zone divided into two age groups: 58 people aged 31.54±5.69 and 62 people aged 54.31±7.26 participated in a study. Results: Age-related differences in the associated indicators of GDV grams and HRV were shown with many correlations between the two methods. Conclusions: The results obtained testify to a deep interrelation and coherence of the system energetic processes of metabolism in the human body, and the fact that the human body is an integral complex hierarchical system of information-energetic interactions, the scientific study, and understanding of which can lead to further advances in both fundamental pieces of knowledges and contribute to the optimization of diagnosis, treatment, and prevention of non-infectious diseases. The results obtained confirm the validity of using the selected set of methods as promising methods for evaluating the human body's psychophysiological state for further practical implementation in practical health care. [ABSTRACT FROM AUTHOR]

Numerous studies in experiments on laboratory animals and in clinical practice have confirmed the positive effect of essential phospholipids on the structural organization of cell membranes, intracellular metabolism, mitochondrial function, antioxidant processes, which explains the active use of phospholipid-containing drugs in hepato- and enteropathologies, cardiovascular diseases, etc. The raw material of animal origin, in particular milk, which is a safe source of biologically active substances, has a structural similarity with phospholipids of mammalian tissues. Based on them, a biologically active additive (BAA) "FLP-MD" was created, which is characterized by membranotropic properties and reparative effect. The aim of this work was to investigate the biological effect of the liposomal form of BAA "FLP-MD" based on milk phospholipids on the body of clinically healthy laboratory mice. Determination of the toxicity of phospholipid-containing BAA "FLP-MD" was performed on mice of the CBA line. The duration of the experiment was 16 days. The results of the studies indicate a probable increase in body weight of mice of the CBA line after the 10th day of intragastric administration of 1% solution of liposomal form of BAA "FLP-MD". As a result of the study of biochemical parameters of plasma / native blood, the absence of toxic effects of the liposomal form of BAA "FLP-MD" on the functional state of the body of mice was set. Morphological parameters of peripheral blood in these animals did not change significantly. According to the results of microscopic studies, no negative effect of the liposomal form of BAA "FLP-MD" on the structure microstructure of the mucous membrane of the gastrointestinal tract was found. Therefore, the components of BAA "FLP-MD" do not adversely affect the functional state of organs and systems of laboratory mice and do not show a toxic effect, which allows it to be recommended for use in veterinary medicine as a means of rehabilitation therapy. [ABSTRACT FROM AUTHOR]

The article presents the results of researches of influence of working conditions of mechanics-drivers, who carry out defoliation of cotton by new import substituting low-toxic defoliants on the functional state of different systems of organism. It is revealed that working conditions and character of working processes at defoliation cause unfavorable shifts of physiological reactions of different systems of organism at mechanics-drivers, and noise and intense character of working process cause probability of risk of development of professionally caused diseases that specifies necessity of introduction of measures on improvement of working conditions. [ABSTRACT FROM AUTHOR]

This paper analyzes the results of the study of the long-term effect of physical exercising and sports in the age range, including late periods of human ontogeny, from the standpoint of the oxidative stress theory. To study the features of the ontogenetic variability of the functional state of the organism, a comparative study of the indices of the functional state of the organism was carried out under different regimes of motor activity at different age stages of development: in sport veterans who continue active motor activity after the termination of a sports career, in former sportsmen leading a sedentary lifestyle, in individuals engaged in recreational forms of exercise, and in individuals who were never regularly engaged in physical education. The contingent of male subjects of different ages also included former athletes and coaches of national teams for cyclical and game sports that require a predominant endurance. As a result of the study, a model was developed that reflects the features and mechanisms of ontogenetic variability of the functional state of the organism under the influence of different regimes of motor activity. [ABSTRACT FROM AUTHOR]

Methods are proposed for measurements, system analysis, and processing of electrocardiographic information. A classification is presented for the functional state of the organism by the introduction of a norm to the control regime of the heart rate. Within the framework of a model for the control system and a regulation system for the physical state of a healthy organism by means of a regimen for the heart-rate variability, adaptive mechanisms are represented in the form of convertibility functions of these systems. [ABSTRACT FROM AUTHOR]

The role and importance of the method of estimating the variability of the heart rhythm from data of group and series ECG recordings are determined. In group analysis of the parameters, the variability becomes a factor in the functional state of the organism, while in a time series of recordings, a factor in its prognosis. [ABSTRACT FROM AUTHOR]