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3D printing technology has a wide range of applications in many industries, including automotive, aerospace, biomedical, electronics and packaging, requiring different types of filaments to be used in producing 3D printed objects. The most commonly used materials are metals, ceramics, composites and plastics of which the latter are most available. Since it is necessary to reduce pollution caused by waste from conventional petroleum-based plastics, biodegradable polymers made from renewable resources or produced synthetically have gained in importance recently. Polylactic acid, poly(butylene succinate), thermoplastic starch, poly(butylene adipate co-terephthalate) and polycaprolactone are well-known representatives of this group of materials. They possess desirable properties for 3D printing which make them promising materials in many areas of applications.

Persistent luminescent materials are those which can store an amount of energy locally and release it slowly in the form of light. In this work, persistent luminescent nanoparticles (PLNPs) were synthesized and incorporated into polypropylene (PP) filaments at various loading percentages. We investigated the optical properties of both the as-prepared PLNPs and the PLNP-loaded filaments, focusing on any changes resulting from the integration into the filaments. Specifically, visible and near-infrared spectroscopy were used to analyze the emission, excitation, and persistent luminescence of the PLNPs and PLNP-loaded filaments. The tensile properties of the extruded filaments were also investigated through breaking tenacity, elongation at break, Young's modulus, and secant modulus. All PLNP-loaded filaments were shown to exhibit persistent luminescence when exposed to ultraviolet light. While there were no significant changes in the elongation at break or Young's modulus for the loading percentages tested, there was a slight increase in breaking tenacity and a decrease in the secant modulus. Finally, the filaments were shown to maintain their optical properties and persistent luminescence even after abrasion testing used to simulate the normal wear and tear that fabric experiences during use. These results show that PLNPs can be successfully incorporated into filaments which can be used in fabrics and will maintain the persistent luminescent properties. [ABSTRACT FROM AUTHOR]

3D printing technology has a wide range of applications in many industries, including automotive, aerospace, biomedical, electronics and packaging, requiring different types of filaments to be used in producing 3D printed objects. The most commonly used materials are metals, ceramics, composites and plastics of which the latter are most available. Since it is necessary to reduce pollution caused by waste from conventional petroleum-based plastics, biodegradable polymers made from renewable resources or produced synthetically have gained in importance recently. Polylactic acid, poly(butylene succinate), thermoplastic starch, poly(butylene adipate co-terephthalate) and polycaprolactone are well-known representatives of this group of materials. They possess desirable properties for 3D printing which make them promising materials in many areas of applications. [ABSTRACT FROM AUTHOR]

A host of metabolic enzymes reversibly self‐assemble to form membrane‐less, intracellular filaments under normal physiological conditions and in response to stress. Often, these enzymes reside at metabolic control points, suggesting that filament formation affords an additional regulatory mechanism. Examples include cytidine‐5′‐triphosphate (CTP) synthase (CTPS), which catalyzes the rate‐limiting step for the de novo biosynthesis of CTP; inosine‐5′‐monophosphate dehydrogenase (IMPDH), which controls biosynthetic access to guanosine‐5′‐triphosphate (GTP); and ∆1‐pyrroline‐5‐carboxylate (P5C) synthase (P5CS) that catalyzes the formation of P5C, which links the Krebs cycle, urea cycle, and proline metabolism. Intriguingly, CTPS can exist in co‐assemblies with IMPDH or P5CS. Since GTP is an allosteric activator of CTPS, the association of CTPS and IMPDH filaments accords with the need to coordinate pyrimidine and purine biosynthesis. Herein, a hypothesis is presented furnishing a biochemical connection underlying co‐assembly of CTPS and P5CS filaments – potent inhibition of CTPS by glutamate γ‐semialdehyde, the open‐chain form of P5C. [ABSTRACT FROM AUTHOR]

There is a growing need to address waste generated from Fused Filament Fabrication (FFF) 3D printing activities. This study explores the mechanical recycling of waste polylactic acid (PLA) accumulated from failed 3D printing operations and PLA biocomposite filaments containing nanocellulose fibres. FFF 3D printable filaments were produced via melt mixing and extrusion of virgin PLA containing varying amounts of waste PLA. The chemical, thermal and thermomechanical characterisation of each specimen was evaluated using Fourier‐transform infrared spectroscopy (FTIR), simultaneous thermal analysis (SDT), dynamic mechanical analysis (DMA), and uniaxial tensile analysis (UTA). A desktop FFF 3D printer was used to fabricate UTA and DMA test specimens. The thermal stability of the filament specimens containing waste derived from the failed 3D prints were comparable with that of the commercial filaments. However, a 11% decrease in the onset of thermal degradation is observed for the filament containing waste biocomposites. The specimens containing waste PLA exhibited higher crystallinity and storage modulus. UTA results revealed similar tensile strength and % elongation, except for the specimen containing 50% waste PLA which exhibited a 29% decrease in tensile strength. This work successfully demonstrates mechanical recycling as a viable waste management strategy for waste materials generated during FFF 3D printing. [ABSTRACT FROM AUTHOR]

This study aimed to construct hydrogel filaments of varying diameters and investigate their behavior over time. Hydrogels were synthesized using different concentrations of sodium alginate and gelatin. The wet spinning technique was employed to produce the hydrogel filaments, utilizing syringes with varying needle sizes and calcium chloride as a crosslinking agent. The filaments were subjected to electromechanical tensile testing to assess their mechanical strength. Additionally, degradation tests were conducted in water to evaluate the porosity of the hydrogel material. The results showed that filaments produced with larger gauge needles exhibited higher electromechanical traction and reduced elongation, while those produced with smaller gauge needles displayed lower resistance to traction but higher stretchability. Storage time did not significantly impact the behavior of the filaments, indicating their durability over time. Moreover, the swelling and degradation tests demonstrated that hydrogels with higher sodium alginate concentrations absorbed liquid faster and degraded more slowly, whereas those with lower gelatin concentrations absorbed liquid more slowly but degraded at a faster rate. In conclusion, the developed hydrogel filaments exhibited varying electromechanical strengths depending on their diameters. Furthermore, they retained their properties over time and their absorption and degradation characteristics were influenced by the composition of the hydrogel material. [ABSTRACT FROM AUTHOR]

A review of recent advances in simulations of turbulent filaments with relevance to stellarators is presented. Progress in performing global edge turbulence simulations is discussed as well as results from seeded filament simulations with applications to the unique environment of a stellarator island divertor-including abrupt changes in connection length and highly-nonuniform curvature drive. It is determined that the motion of filaments generally follows the average curvature, but strong nonuniform perturbations can shear a filament and reduce the overall transport. The coherence of filament transport is also determined to be influenced by the collisionality and electron plasma beta. By simplifying the simulation geometries, large parameter scans can be performed which accurately reflect the macroscopic transport of filaments observed in Wendelstein 7-X. Comparisons to experiments are discussed, and a the develeopment of a synthetic diagnostic has been able to inform experimental measurements by quantifying potential sources of error in filament propagation measurements. A discussion of the necessary extension to more complex multifluid models, and the scope for near-term filament simulations in stellarators, is provided. [ABSTRACT FROM AUTHOR]

Henri Deslandres initiated imaging spectroscopy of the solar atmosphere in 1892 at Paris Observatory. He developed two kinds of spectrographs: the 'spectrohéliographe des formes', i.e. the monochromatic instrument to reveal chromospheric structures (such as filaments, prominences, plages and active regions); and the 'spectrohéliographe des vitesses', i.e. the spectroheliograph to record line profiles of cross-sections of the Sun, in order to measure the Doppler shifts of dynamic features. Deslandres moved to Meudon and hired Lucien d'Azambuja in 1899; together they built the large quadruple spectroheliograph. CaII K systematic observations of the full Sun started in 1908 and were followed in 1909 by Hα with two dedicated 3-metre spectroheliographs. Daily observations were organized by d'Azambuja who also intensively used the large 7-metre spectroheliograph for his research and thesis (1930). This paper summarizes fifty years of investigations by Mr and Mrs d'Azambuja, who explored various photospheric and chromospheric lines, obtaining special spectroheliograms with the high dispersion 7-metre instrument. They also intensively observed filaments and prominences, reported results in an extensive memoir (1948) and recorded rare solar activity events with the two 3-metre spectroheliographs, until their retirement in 1959. [ABSTRACT FROM AUTHOR]

The aim of this study was to fabricate mini-tablets of polyhedrons containing theophylline using a fused deposition modeling (FDM) 3D printer, and to evaluate the correlation between release kinetics models and their geometric shapes. The filaments containing theophylline, hydroxypropyl cellulose (HPC), and EUDRAGIT RS PO (EU) could be obtained with a consistent thickness through pre-drying before hot melt extrusion (HME). Mini-tablets of polyhedrons ranging from tetrahedron to icosahedron were 3D-printed using the same formulation of the filament, ensuring equal volumes. The release kinetics models derived from dissolution tests of the polyhedrons, along with calculations for various physical parameters (edge, SA: surface area, SA/W: surface area/weight, SA/V: surface area/volume), revealed that the correlation between the Higuchi model and the SA/V was the highest (R2 = 0.995). It was confirmed that using 3D- printing for the development of personalized or pediatric drug products allows for the adjustment of drug dosage by modifying the size or shape of the drug while maintaining or controlling the same release profile. [ABSTRACT FROM AUTHOR]

The 2D insulating material hexagonal boron nitride (h‐BN) has attracted much attention as the active medium in memristive devices due to its favorable physical properties, among others, a wide bandgap that enables a large switching window. Metal filament formation is frequently suggested for h‐BN devices as the resistive switching (RS) mechanism, usually supported by highly specialized methods like conductive atomic force microscopy (C‐AFM) or transmission electron microscopy (TEM). Here, the switching of multilayer hexagonal boron nitride (h‐BN) threshold memristors with two nickel (Ni) electrodes is investigated through their current conduction mechanisms. Both the high and the low resistance states are analyzed through temperature‐dependent current–voltage measurements. The formation and retraction of nickel filaments along boron defects in the h‐BN film as the resistive switching mechanism is proposed. The electrical data are corroborated with TEM analyses to establish temperature‐dependent current–voltage measurements as a valuable tool for the analysis of resistive switching phenomena in memristors made of 2D materials. The memristors exhibit a wide and tunable current operation range and low stand‐by currents, in line with the state of the art in h‐BN‐based threshold switches, a low cycle‐to‐cycle variability of 5%, and a large On/Off ratio of 107. [ABSTRACT FROM AUTHOR]

Polycaprolactone (PCL) is a biocompatible polymer readily moldable into various shapes and designs. However, its low mechanical strength and slow biodegradation restrict its use in tissue engineering. Magnesium (Mg), a biocompatible metal with excellent osteoconductivity and biodegradability, is a promising choice for tissue engineering applications. This study investigates the influence of Mg incorporation on the properties of PCL/Mg composites, aiming to evaluate their suitability for 3D-printable (3DP) tissue engineering applications. We synthesized a series of PCL/Mg composites with varying Mg concentrations and characterized their mechanical, thermal, and degradation properties. According to microscopic analysis of the composite films, the Mg particles are dispersed consistently throughout all the compositions. The findings demonstrated that adding Mg influenced PCL's mechanical and thermal properties. The mechanical test results showed that the tensile strength of 15% Mg composite filaments improved by around 10% compared to the neat PCL filaments. However, the elastic modulus decreased by around 50% for the same composition. The thermal study revealed a significant reduction in the degradation temperature from above 400℃ for pure PCL to around 300°C for PCL/Mg composite having 15% Mg. Additionally, the weight loss during in vitro degradation showed that the presence of Mg had significantly increased the degradation rate of composite samples. Also, Mg incorporation influences cell adhesion, with better attachment observed for 10% Mg 3DP samples. Overall, PCL/Mg composites offer a solution to overcome the limitation of low thermo-mechanical properties typically associated with the PCL. [ABSTRACT FROM AUTHOR]

Resistive switching devices based on metal oxides are candidates for nonvolatile memory storage. They often rely on the valence change mechanism, the field‐induced movement of donor ions leading to nanoscale conductive paths in filamentary‐type devices. Devices usually consist of a transition metal oxide like Ta2O5 sandwiched between two metal electrodes. Critical parameters of the devices, such as cycle‐to‐cycle variability, Roff/Ron ratio, and endurance depend on the morphology and composition of the filaments. However, investigating filaments on the nanoscale is cumbersome, and commonly applied techniques such as conductive atomic force or transmission electron microscopy require delaminating the metal top electrode, inhibiting in operando investigations over many switching cycles. Here, the authors use infrared scattering‐type scanning near‐field optical microscopy (s‐SNOM) to investigate resistive switching in Ta2O5 films with a graphene top electrode in operando and reveal individual filaments on the device level. By selecting an appropriate illumination frequency, the authors can trace the evolution of filaments and the joule heating‐induced retraction of the top electrode until device failure. s‐SNOM promises a deeper understanding of resistive switching devices' microscopic switching behavior and applies to a wide range of resistive switching oxides, such as HfO2, SrTiO3, and SiO2. [ABSTRACT FROM AUTHOR]

The increased use of plastics in industrial and agricultural applications has led to high levels of pollution worldwide and is a significant challenge. To address this plastic pollution, conventional methods such as landfills and incineration are used, leading to further challenges such as the generation of greenhouse gas emissions. Therefore, increasing interest has been directed to identifying alternative methods to dispose of plastic waste from agriculture. The novelty of the current research arose from the lack of critical reviews on how 3-Dimensional (3D) printing was adopted for recycling plastics, its application in the production of agricultural plastics, and its specific benefits, disadvantages, and limitations in recycling plastics. The review paper offers novel insights regarding the application of 3D printing methods including Fused Particle Fabrication (FPF), Hot Melt Extrusion (HME), and Fused Deposition Modelling (FDM) to make filaments from plastics. However, the methods were adopted in local recycling setups where only small quantities of the raw materials were considered. Data was collected using a systematic review involving 39 studies. Findings showed that the application of the 3D printing methods led to the generation of agricultural plastics such as Polylactic Acid (PLA), Acrylonitrile Butadiene Styrene (ABS), Polyethylene Terephthalate (PET), and High-Density Polyethylene (HDPE), which were found to have properties comparable to those of virgin plastic, suggesting the viability of 3D printing in managing plastic pollution. However, limitations were also associated with the 3D printing methods; 3D-printed plastics deteriorated rapidly under Ultraviolet (UV) light and are non-biodegradable, posing further risks of plastic pollution. However, UV stabilization helps reduce plastic deterioration, thus increasing longevity and reducing disposal. Future directions emphasize identifying methods to reduce the deterioration of 3D-printed agricultural plastics and increasing their longevity in addition to UV stability. [ABSTRACT FROM AUTHOR]

Hot melt extrusion (HME) is a common manufacturing process used in the pharmaceutical industry to improve the solubility of poorly soluble active pharmaceutical ingredients (API). The goal is to create an amorphous solid dispersion (ASD) where the amorphous form of the API is stabilized within a polymer matrix. Traditionally, the development of pharmaceutically approved polymers has focused on requirements such as thermal properties, solubility, drug–polymer interactions, and biocompatibility. The mechanical properties of the material have often been neglected in the design of new polymers. However, new downstream methods require more flexible polymers or suitable plasticizer polymer combinations. In this study, two grades of the polymer polyvinyl alcohol (PVA), which is already established for HME, are investigated in terms of their mechanical, rheological, and thermal properties. The mechanical properties of the extruded filaments were tested by the three-point bending test. The rheological behavior was analyzed by oscillating plate measurements. Thermal analysis was performed by differential scanning calorimetry (DSC). In addition, the solid and liquid plasticizers mannitol, sorbitol, triacetin, triethyl citrate, polyethylene glycol, and glycerol were evaluated for use with PVA and their impact on the polymer properties was elaborated. Finally, the effects of the plasticizers are compared to each other, and the correlations are analyzed statistically using principal component analysis (PCA). Thereby, a clear ranking of the plasticizer effects was established, and a deeper understanding of the polymer–plasticizer interactions was created. [ABSTRACT FROM AUTHOR]

Background: The ability of minor subpopulations among clonal populations to survive antibiotics is referred to as bacterial persistence. It is believed that persisters come from latent cells, where antibiotic target areas are less active and incapable of being affected. Objective: 112 clinical Escherichia coli isolates were acquired out of diverse medical samples and genetically identified using the uspA gene, which is part of the housekeeping genes. Methods: The examination of persister cells was carried out by subjecting isolates of E. coli in the exponential phase with high dose of ciprofloxacin (20 fold MIC) and calculating the surviving persister cells using CFU (colony forming units) counts. The detection and measurement of bacterial filament production was done using scanning electron and light microscopy. Results: Results showed that the bacterial filament cells kept on lengthen but cease to divide (no septa formation) at sub-minimal inhibitory doses of ciprofloxacin. Persistent isolates were shown to exhibit a wide range of form and size variations, with cells up to 4.5 times longer than usual. Conclusions: The results showed the importance of antibiotic stress on persisted cells that result in the production of filaments as a means of survival and the need to examine these rare phenotypic variations. These occurrences may be the beginning of the spread of bacterial resistance. [ABSTRACT FROM AUTHOR]

Abstract There is a growing need to address waste generated from Fused Filament Fabrication (FFF) 3D printing activities. This study explores the mechanical recycling of waste polylactic acid (PLA) accumulated from failed 3D printing operations and PLA biocomposite filaments containing nanocellulose fibres. FFF 3D printable filaments were produced via melt mixing and extrusion of virgin PLA containing varying amounts of waste PLA. The chemical, thermal and thermomechanical characterisation of each specimen was evaluated using Fourier‐transform infrared spectroscopy (FTIR), simultaneous thermal analysis (SDT), dynamic mechanical analysis (DMA), and uniaxial tensile analysis (UTA). A desktop FFF 3D printer was used to fabricate UTA and DMA test specimens. The thermal stability of the filament specimens containing waste derived from the failed 3D prints were comparable with that of the commercial filaments. However, a 11% decrease in the onset of thermal degradation is observed for the filament containing waste biocomposites. The specimens containing waste PLA exhibited higher crystallinity and storage modulus. UTA results revealed similar tensile strength and % elongation, except for the specimen containing 50% waste PLA which exhibited a 29% decrease in tensile strength. This work successfully demonstrates mechanical recycling as a viable waste management strategy for waste materials generated during FFF 3D printing.

For this study, we employed intense 400 nm, 100 fs pulses linearly propagated through a 50 cm water medium, initially self-stretching the excitation pulses to 2.50 ps. Subsequently, the self-stretched 2.50 ps pulses were focused into deionized water, and we conducted transient absorption experiments to measure and investigate the dynamics of hydrated electrons in water. The excess electrons generated were injected into the hydrogen bond network of the water cluster, leading to the observation of saturated hydrated electrons. Additionally, we observed the emergence of the forward stimulated Raman scattering (SRS) of water molecules. We report the experimental observation of a weak forward SRS emission at 463 nm (corresponding to 3400 cm−1), indicative of the ordinary OH stretching vibration in the liquid phase. Moreover, we observed an intense forward SRS emission at 460 nm in water, corresponding to two anomalous Raman shifts at 3260 cm−1 and 3355 cm−1. These anomalous Raman shifts resulted from changes in the hydrogen bond network structure. We determine that the formation of not fully hydrated and saturated hydrated electrons plays a crucial role in producing this phenomenon. [ABSTRACT FROM AUTHOR]

The very outer solar atmosphere (corona) is very hot with temperatures over a million degrees K, while the photosphere is of the order of 5000 K. Embedded in this hot outer corona are cool, =10,000 K, magnetic structures called solar prominences. As seen on the disk, they are long filamentary structures while on the solar limb they look like intricate loops. In this paper, we present the development of our understanding of solar prominences, which have played a central role in the development of solar science. Solar prominences were first observed during the few minute episodes of total eclipses. The introduction of spectroscopy allowed continuous observations, which also led to information on temperatures, temporal variations and dynamics of the associated plasma. The discovery of strong magnetic fields in sunspots provided a breakthrough in our understanding of the physics of the Sun. Weaker magnetic fields formed both the large and small-scale structures of prominences, their time-variable shapes, and explained why they could remain floating high above the solar surface in the less dense corona. Appearing as dark, thin, elongated filaments against a brighter solar disk, they provided further information through their interaction with and dependence on how magnetic fields are distributed on the solar surface, in the chromosphere and corona. Access to X-ray and short-wavelength ultraviolet radiation in prominences from spacecraft revealed large ranges of temperature in thin layers between the 10,000-degree prominence cores and the surrounding million-degree corona. The advent of increasingly more powerful computers has led to advanced modelling of prominence plasma based on radiative transfer and magnetohydrodynamic (MHD) calculations. Theoretical and observational progress has opened up new possible formation mechanisms. The spectacular eruptions of solar prominences have led to a considerable amount of observational and theoretical work on possibly similar events on other stars, which could affect the existence of life on their orbiting planets. [ABSTRACT FROM AUTHOR]

As is well known, magnetic fields in space are distributed very inhomogeneously. Sometimes, field distributions have forms of filaments with high magnetic field values. As many observations show, such a filamentation takes place in convective cells in the Sun and other astrophysical objects. This effect is associated with the frozenness of the magnetic field into a medium with high conductivity that leads to the compression of magnetic field lines and formation of magnetic filaments. We analytically show, based on the general analysis, that the magnetic field intensifies in the regions of downward flows in both two-dimensional and three-dimensional convective cells. These regions of the hyperbolic type in magnetic fields play the role of a specific attractor. This analysis was confirmed by numerical simulations of 2D roll-type convective cells. Without dissipation, the magnetic field grows exponentially in time and does not depend on the aspect ratio between the horizontal and vertical scales of the cell. An increase due to compression in the magnetic field of highly conductive plasma is saturated due to the natural limitation associated with dissipative effects when the maximum magnitude of a magnetic field is of the order of the root of the magnetic Reynolds number Rem. For the solar convective zone, the mean kinetic energy density exceeds the mean magnetic energy density for at least two orders of magnitude, which allows one to use the kinematic approximation of the MHD induction equation. In this paper, based on the stability analysis, we explain why downward flows influence magnetic filaments, making them flatter with orientation along the interfaces between convective cells. [ABSTRACT FROM AUTHOR]

A paradigm shift is taking place in the conception of solar cycles. In the previous conception, the changing numbers of sunspots over intervals of 9-14 years have been regarded as the fundamental solar cycle although two average 11-year cycles were necessary to account for the complete magnetic cycle. In the revised picture, sunspots are a phase in the middle of two 22-year overlapping solar cycles that operate continuously with clock-like precision. More than 20 researchers have contributed to the initial research articles from 2014 through 2021 which are dramatically altering the perception of solar cycles. The two 22-year cycles overlap in time by 11 years. This overlap is coincidentally the same average duration as the sunspot phase in each 22-year cycle. This coincidence and the relative lack of knowledge of the large numbers of small active regions without sunspots is what led to the previous paradigm in which the 11-year sunspot phases were misinterpreted as a single fundamental solar cycle. The combination of the two 22-year solar cycles, with their large numbers of short-lived active regions and ephemeral active regions are now understood to be the fundamental cycle with the proposed name "The Hale Solar Cycle." The two 22-year solar cycles each occupy separate but adjacent bands in latitude. The orientations of the majority of bipolar magnetic regions in the two adjacent bands differ from each other by ∼180°. Both bands continuously drift from higher to lower latitudes as has been known for sunspot cycles. However, the polarity reversal occurs at the start of each 22-year cycle and at higher latitudes than it does for the sunspot cycles. This paradigm shift in the concept of solar cycles has resulted in major reconsiderations of additional topics on solar cycles in this review. These are 1) the large role of ephemeral active regions in the origin of solar cycles, 2) the depth of the origin of active regions and sunspots, 3) the mechanisms of how areas of unipolar magnetic network migrate to the solar poles every 11 years, and 4) the nature of the polarity reversal in alternate 22-year cycles rather than 11-year cycles. [ABSTRACT FROM AUTHOR]

The first results of investigation of edge localized modes (ELMs) in the Globus-M2 tokamak using the Doppler backscattering method are presented in this paper. Specifically, ELMs that are initiated by sawtooth crashes in the H-mode are discussed. The goal of this paper is study plasma turbulence behaviour during ELMs and to showcase what ELM characteristics can be obtained using Doppler backscattering (DBS). An increase of the poloidal rotation velocity during an ELM burst and a decrease in the inter-ELM periods was observed. The effect of ELMs on the plasma turbulence was investigated and estimated to span around 6 cm inside the separatrix. This is to do with the fact that the sawtooth crashes which are responsible for initiating the ELMs take place in the core plasma. Additional experiments with standard reflectometry indicate that ELMs develop 3 cm inside the separatrix where the pedestal region is believed to be in Globus-M2. The direction of the expansion of the ELMs from the inner plasma region to the edge was determined and the velocity was estimated to be around 8 km s−1. During a single ELM burst a series of filament structures were found in the peripheral DBS channels. In an attempt to understand the processes involved modelling of the reaction of the DBS signals to filaments was done using the BOUT ++ and IPF-FD3D full-wave codes, and the cases for both linear and nonlinear scattering were considered. The results show that the presence of nonlinear scattering during ELMs can lead to an overestimation of the measured velocity values in the region of filament existence near the separatrix. [ABSTRACT FROM AUTHOR]

Additive manufacturing has garnered significant attention as a versatile method for fabricating green and complex composite materials. This study delves into the fabrication of polymer composites by employing polylactic acid (PLA) in conjunction with rice husk as a reinforcing filler. The filaments were made by an extruded filament maker and then were used to make tensile and impact samples by another extrusion technology, fused deposition modeling (FDM). The structural and morphological characteristics of the composite materials were analyzed using scanning electron microscopy SEM. Results show that both the filament and samples are very reliable in producing polymer parts with this rice husk solid waste. This research contributes to increasing materials' circularity and potentially creating a local social economy around rice production, where this waste is not much used. [ABSTRACT FROM AUTHOR]

The current experimental study investigates some aspects of the electrical discharge properties between two planar electrodes. These properties involve the relationships of the minimum sparking potential to the electrode separation, the spark repetition rate, and the distribution of discharge pulse height concerning both the applied voltage and electrode separation. These discharge parameters tend to show nonlinear relationship with both applied voltage and electrode separation. [ABSTRACT FROM AUTHOR]

Background: The ability of minor subpopulations among clonal populations to survive antibiotics is referred to as bacterial persistence. It is believed that persisters come from latent cells, where antibiotic target areas are less active and incapable of being affected. Objective: 112 clinical Escherichia coli isolates were acquired out of diverse medical samples and genetically identified using the uspA gene, which is part of the housekeeping genes. Methods: The examination of persister cells was carried out by subjecting isolates of E. coli in the exponential phase with high dose of ciprofloxacin (20 fold MIC) and calculating the surviving persister cells using CFU (colony forming units) counts. The detection and measurement of bacterial filament production was done using scanning electron and light microscopy. Results: Results showed that the bacterial filament cells kept on lengthen but cease to divide (no septa formation) at sub-minimal inhibitory doses of ciprofloxacin. Persistent isolates were shown to exhibit a wide range of form and size variations, with cells up to 4.5 times longer than usual. Conclusions: The results showed the importance of antibiotic stress on persisted cells that result in the production of filaments as a means of survival and the need to examine these rare phenotypic variations. These occurrences may be the beginning of the spread of bacterial resistance.

A review of recent advances in simulations of turbulent filaments with relevance to stellarators is presented. Progress in performing global edge turbulence simulations is discussed as well as results from seeded filament simulations with applications to the unique environment of a stellarator island divertor–including abrupt changes in connection length and highly-nonuniform curvature drive. It is determined that the motion of filaments generally follows the average curvature, but strong nonuniform perturbations can shear a filament and reduce the overall transport. The coherence of filament transport is also determined to be influenced by the collisionality and electron plasma beta. By simplifying the simulation geometries, large parameter scans can be performed which accurately reflect the macroscopic transport of filaments observed in Wendelstein 7-X. Comparisons to experiments are discussed, and a the develeopment of a synthetic diagnostic has been able to inform experimental measurements by quantifying potential sources of error in filament propagation measurements. A discussion of the necessary extension to more complex multifluid models, and the scope for near-term filament simulations in stellarators, is provided.

Polycaprolactone (PCL) is a biocompatible polymer readily moldable into various shapes and designs. However, its low mechanical strength and slow biodegradation restrict its use in tissue engineering. Magnesium (Mg), a biocompatible metal with excellent osteoconductivity and biodegradability, is a promising choice for tissue engineering applications. This study investigates the influence of Mg incorporation on the properties of PCL/Mg composites, aiming to evaluate their suitability for 3D-printable (3DP) tissue engineering applications. We synthesized a series of PCL/Mg composites with varying Mg concentrations and characterized their mechanical, thermal, and degradation properties. According to microscopic analysis of the composite films, the Mg particles are dispersed consistently throughout all the compositions. The findings demonstrated that adding Mg influenced PCL’s mechanical and thermal properties. The mechanical test results showed that the tensile strength of 15% Mg composite filaments improved by around 10% compared to the neat PCL filaments. However, the elastic modulus decreased by around 50% for the same composition. The thermal study revealed a significant reduction in the degradation temperature from above 400°C for pure PCL to around 300°C for PCL/Mg composite having 15% Mg. Additionally, the weight loss during in vitro degradation showed that the presence of Mg had significantly increased the degradation rate of composite samples. Also, Mg incorporation influences cell adhesion, with better attachment observed for 10% Mg 3DP samples. Overall, PCL/Mg composites offer a solution to overcome the limitation of low thermo-mechanical properties typically associated with the PCL.

At the moment, there is a growing interest in composite materials with matrices based on thermoplastic polymers; these materials are superior to traditional carbon fiber plastics due to higher fracture toughness and impact strength, low smoke generation during combustion, and high thermal and chemical resistance. The deformation behavior of such composite materials due to the high plastic deformation of the matrix differs from the behavior of traditional composites, which must be considered when performing calculations. In our study, as a model object, the features of the microstructure of single carbon thread impregnated with polysulfone were studied in order to evaluate the distribution of misorientation angles of elementary fibers, the degree of their damage, the thickness of the polymer matrix interlayers between elementary fibers in threads impregnated with more viscous thermoplastic binders. Statistical analysis of a large array of micrographs was carried out using specially developed algorithms for computer processing of electron microscopic images of a composite material. Algorithms for processing arrays of images using machine vision algorithms are proposed. Based on the analysis of the data array, the distributions of carbon fibers impregnated with polysulfone were plotted over the misorientation angle of the filaments and over the interfilament distance in the longitudinal and cross sections of the fiber. Using the machine learning method, an algorithm for detecting violations of the filament structure was implemented. The data obtained can be used to refine the calculations of the strength and deformation characteristics of composite materials with thermoplastic matrices.

Abstract Background Effective dental plaque removal is essential for oral health. Different toothbrush parameters including head-size, filament-diameter and interdent-height and different brushing movements like horizontal, rotating and vertical may affect plaque removal efficacy. The purpose of the study was to examine plaque removal efficacy of different design parameters of manual toothbrushes. Methods Eight manual toothbrushes were tested using a validated robot test to examine efficacy of toothbrush on replicated human teeth. Characteristics tested were: (i) head-size, (ii) filament-diameter, (iii) cutting-height, (iv) hardness, (v) interdental-height. Each test ran five times in horizontal, rotating, vertical movements. Simulated Plaque removal was evaluated using automated plaque planimetry: 30 fields/tooth, 13 areas representing buccal, lingual, proximal tooth sites. The Kolmogorov-Smirnov-test was applied to test tooth surface variables for normal distribution of plaque removal values. Parameters were analysed by independent two-sample t-test to assess mean differences. Where null hypothesis of normality was rejected, the Wilcoxon-Mann-Whitney-U-test was used. Results Plaque removal was significantly better with toothbrush having smaller head-size (compact vs. full-size); smaller filament-diameter (0.12 mm vs. 0.15 mm); larger cutting-height (12 mm vs. 9 mm); softer filaments (0.15 or 0.18 mm vs. 0.23 mm) and greater interdent-height difference (8.5/11 mm vs. 10/11 mm). Conclusions Manual brushes allowing filaments free to flex with longer, softer and/or having a difference in filament length overall removed significantly more simulated plaque as compared to more standard flat trim, stiff brushes with shorter, harder bristles and a larger head size. While limited by the in vitro nature of the study design, this indicates that the advances in toothbrush design can further enhance plaque removal.

The current experimental study investigates some aspects of the electrical discharge properties between two planar electrodes. These properties involve the relationships of the minimum sparking potential to the electrode separation, the spark repetition rate, and the distribution of discharge pulse height concerning both the applied voltage and electrode separation. These discharge parameters tend to show nonlinear relationship with both applied voltage and electrode separation.

A paradigm shift is taking place in the conception of solar cycles. In the previous conception, the changing numbers of sunspots over intervals of 9–14 years have been regarded as the fundamental solar cycle although two average 11-year cycles were necessary to account for the complete magnetic cycle. In the revised picture, sunspots are a phase in the middle of two 22-year overlapping solar cycles that operate continuously with clock-like precision. More than 20 researchers have contributed to the initial research articles from 2014 through 2021 which are dramatically altering the perception of solar cycles. The two 22-year cycles overlap in time by 11 years. This overlap is coincidentally the same average duration as the sunspot phase in each 22-year cycle. This coincidence and the relative lack of knowledge of the large numbers of small active regions without sunspots is what led to the previous paradigm in which the 11-year sunspot phases were misinterpreted as a single fundamental solar cycle. The combination of the two 22-year solar cycles, with their large numbers of short-lived active regions and ephemeral active regions are now understood to be the fundamental cycle with the proposed name “The Hale Solar Cycle.” The two 22-year solar cycles each occupy separate but adjacent bands in latitude. The orientations of the majority of bipolar magnetic regions in the two adjacent bands differ from each other by ∼180°. Both bands continuously drift from higher to lower latitudes as has been known for sunspot cycles. However, the polarity reversal occurs at the start of each 22-year cycle and at higher latitudes than it does for the sunspot cycles. This paradigm shift in the concept of solar cycles has resulted in major reconsiderations of additional topics on solar cycles in this review. These are 1) the large role of ephemeral active regions in the origin of solar cycles, 2) the depth of the origin of active regions and sunspots, 3) the mechanisms of how areas of unipolar magnetic network migrate to the solar poles every 11 years, and 4) the nature of the polarity reversal in alternate 22-year cycles rather than 11-year cycles.

In high confinement mode (H-mode) in the tokamak Globus-M2, the development of edge-localized modes (ELMs) is accompanied by the appearance of filament structures. Using the Doppler backscattering method allowed to determine the parameters of the filaments during ELMs triggered by and independent from saw-tooth crashes. It was shown that the number of filaments observed during ELMs synchronized with saw-tooth crashes is greater and the area of their observation is wider. The filament velocity during all observed ELM types on Globus-M2 is higher than was the case on the Globus-M tokamak. Filaments that developed immediately before an ELM burst are characterized by smaller amplitudes and velocities. Two diagnostics, Doppler backscattering and poloidal correlation Doppler reflectometry, were used to determine the poloidal velocity of such filaments and the results demonstrated that the velocity values obtained had similar values, which may indicate linear backscattering taking place off these filaments. [ABSTRACT FROM AUTHOR]

At the moment, there is a growing interest in composite materials with matrices based on thermoplastic polymers; these materials are superior to traditional carbon fiber plastics due to higher fracture toughness and impact strength, low smoke generation during combustion, and high thermal and chemical resistance. The deformation behavior of such composite materials due to the high plastic deformation of the matrix differs from the behavior of traditional composites, which must be considered when performing calculations. In our study, as a model object, the features of the microstructure of single carbon thread impregnated with polysulfone were studied in order to evaluate the distribution of misorientation angles of elementary fibers, the degree of their damage, the thickness of the polymer matrix interlayers between elementary fibers in threads impregnated with more viscous thermoplastic binders. Statistical analysis of a large array of micrographs was carried out using specially developed algorithms for computer processing of electron microscopic images of a composite material. Algorithms for processing arrays of images using machine vision algorithms are proposed. Based on the analysis of the data array, the distributions of carbon fibers impregnated with polysulfone were plotted over the misorientation angle of the filaments and over the interfilament distance in the longitudinal and cross sections of the fiber. Using the machine learning method, an algorithm for detecting violations of the filament structure was implemented. The data obtained can be used to refine the calculations of the strength and deformation characteristics of composite materials with thermoplastic matrices. [ABSTRACT FROM AUTHOR]

Poly-ether-ether-ketone (PEEK) has several approving mechanical properties; however, for certain demanding applications such as automotive, PEEK does not exhibit the required strength. Moreover, if the PEEK parts are developed by Fused Filament Fabrication (FFF)-based 3D Printing, there is a high chance of having PEEK parts with decreased mechanical properties. Carbon fiber (CF) reinforcement is a well-known method of mitigating the low mechanical properties of PEEK. Hence, in the present study, we attempted to develop CF-reinforced PEEK (CFR-PEEK) parts via FFF. First, we developed homogeneous CFR-PEEK mixtures via ball milling and explored the effects of different milling durations and speeds on the extent of uniform dispersion of the CFs in the PEEK matrix. Next, we fed the CFR-PEEK milled powders into a high-temperature extrusion setup to develop uniform-diameter CFR-PEEK filaments. We analyzed the effects of different extrusion parameters on the uniform-diameter CFR-PEEK filament quality to make it suitable for 3D printing. Finally, the CFR-PEEK filaments were used in a high-temperature FFF setup to develop design-specific parts. Our results indicate that 400 rpm and 4 h were apt for developing uniform CFR-PEEK mixtures. Interestingly, increasing the CF content above 10 vol% resulted in brittle filaments. The extrusion temperature, speed, and cooling rate played a major role in forming the uniform-diameter CFR-PEEK filaments. Finally, the 3D-printed CFR-PEEK parts exhibited a tensile strength of 49 MPa, lesser than unfilled PEEK. We indicate that poor interfacial bonding of the CF with the PEEK matrix is a primary reason for this reduced strength. In addition, printing defects such as pores also contributed to the reduced strength of the CFR-PEEK parts. [ABSTRACT FROM AUTHOR]

Background: Effective dental plaque removal is essential for oral health. Different toothbrush parameters including head-size, filament-diameter and interdent-height and different brushing movements like horizontal, rotating and vertical may affect plaque removal efficacy. The purpose of the study was to examine plaque removal efficacy of different design parameters of manual toothbrushes. Methods: Eight manual toothbrushes were tested using a validated robot test to examine efficacy of toothbrush on replicated human teeth. Characteristics tested were: (i) head-size, (ii) filament-diameter, (iii) cutting-height, (iv) hardness, (v) interdental-height. Each test ran five times in horizontal, rotating, vertical movements. Simulated Plaque removal was evaluated using automated plaque planimetry: 30 fields/tooth, 13 areas representing buccal, lingual, proximal tooth sites. The Kolmogorov-Smirnov-test was applied to test tooth surface variables for normal distribution of plaque removal values. Parameters were analysed by independent two-sample t-test to assess mean differences. Where null hypothesis of normality was rejected, the Wilcoxon-Mann-Whitney-U-test was used. Results: Plaque removal was significantly better with toothbrush having smaller head-size (compact vs. full-size); smaller filament-diameter (0.12 mm vs. 0.15 mm); larger cutting-height (12 mm vs. 9 mm); softer filaments (0.15 or 0.18 mm vs. 0.23 mm) and greater interdent-height difference (8.5/11 mm vs. 10/11 mm). Conclusions: Manual brushes allowing filaments free to flex with longer, softer and/or having a difference in filament length overall removed significantly more simulated plaque as compared to more standard flat trim, stiff brushes with shorter, harder bristles and a larger head size. While limited by the in vitro nature of the study design, this indicates that the advances in toothbrush design can further enhance plaque removal. [ABSTRACT FROM AUTHOR]

In this study, the 3D printing short carbon fiber (SCF) reinforced polypropylene (PP) composite filament was developed. The micro-size SCFs were mixed with PP granules and extruded in a twin screw extruder to develop SCF/PP composite granules. The composite granules were extruded in a single screw extruder and then wound to develop SCF/PP filaments. SCF/PP filaments were produced with varying content of SCF ranging from 4 to 22 wt%. The developed composite filaments were injected by a 3D printer to produce testing samples. 3D printed SCF/PP composites with different SCF contents were investigated by analyzing their mechanical, physical, and morphological properties. The SCF/PP composites developed have shown great enhancement in their mechanical properties (tensile strength and impact toughness). The tensile strength of the 22%SCF/PP composite increased by 150% when compared to the neat PP, while the impact energy of the 22%SCF/PP composite was enhanced by 260% of the neat PP. However, the strain at break values decreased linearly in composites up to 11 wt% SCF content followed by a sudden drop in strain values in composite with 14 wt% SCF.

Morgellons disease is characterized by patient reports of fibers embedded in and protruding from the skin. Etiologies from infection to delusion have been endorsed, and treatment guidelines are not well-defined. The objective of this manuscript is to evaluate the existing evidence regarding the etiology and treatment of Morgellons disease in an effort to better inform clinical management. A PubMed search including key words "Morgellons," "delusional parasitosis and fibers," "delusions of parasitosis and fibers," or "delusional infestation and fibers" was completed. Original publications directly assessing etiology or treatment methods of Morgellons disease published between January, 2010 and the time of manuscript preparation were reviewed and evaluated. Sixteen articles regarding etiology were reviewed. All studies were correlative in nature with various limitations. Support for a psychiatric etiology was more widespread than support for an infectious etiology. Eleven articles regarding treatment efficacy were reviewed. Antipsychotic regimens have the most evidence of efficacy. Existing data regarding Morgellons disease suggests a psychiatric etiology and supports treatment with a low-dose antipsychotic agent once non-psychiatric causes have been excluded.

The aim of this study was to fabricate mini-tablets of polyhedrons containing theophylline using a fused deposition modeling (FDM) 3D printer, and to evaluate the correlation between release kinetics models and their geometric shapes. The filaments containing theophylline, hydroxypropyl cellulose (HPC), and EUDRAGIT RS PO (EU) could be obtained with a consistent thickness through pre-drying before hot melt extrusion (HME). Mini-tablets of polyhedrons ranging from tetrahedron to icosahedron were 3D-printed using the same formulation of the filament, ensuring equal volumes. The release kinetics models derived from dissolution tests of the polyhedrons, along with calculations for various physical parameters (edge, SA: surface area, SA/W: surface area/weight, SA/V: surface area/volume), revealed that the correlation between the Higuchi model and the SA/V was the highest (R2 = 0.995). It was confirmed that using 3D- printing for the development of personalized or pediatric drug products allows for the adjustment of drug dosage by modifying the size or shape of the drug while maintaining or controlling the same release profile.

The results of constructing 3D scaffolds from degradable poly(3-hydrosbutyrpate-co-3-hydroxyvalerate) using FDM technology and studying the structure, mechanical properties, biocompatibility in vitro, and osteoplastic properties in vivo are presented. In the process of obtaining granules, filaments, and scaffolds from the initial polymer material, a slight change in the crystallization and glass transition temperature and a noticeable decrease in molecular weight (by 40%) were registered. During the compression test, depending on the direction of load application (parallel or perpendicular to the layers of the scaffold), the 3D scaffolds had a Young's modulus of 207.52 ± 19.12 and 241.34 ± 7.62 MPa and compressive stress tensile strength of 19.45 ± 2.10 and 22.43 ± 1.89 MPa, respectively. SEM, fluorescent staining with DAPI, and calorimetric MTT tests showed the high biological compatibility of scaffolds and active colonization by NIH 3T3 fibroblasts, which retained their metabolic activity for a long time (up to 10 days). The osteoplastic properties of the 3D scaffolds were studied in the segmental osteotomy test on a model defect in the diaphyseal zone of the femur in domestic Landrace pigs. X-ray and histological analysis confirmed the formation of fully mature bone tissue and complete restoration of the defect in 150 days of observation. The results allow us to conclude that the constructed resorbable 3D scaffolds are promising for bone grafting. [ABSTRACT FROM AUTHOR]

The ability to rapidly characterize dry aerosols in air using laser-induced breakdown spectroscopy (LIBS) with femtosecond laser pulses promises advancement towards real-time atmospheric sampling and standoff capabilities. Of particular interest is the ability to apply LIBS in the context of low-particle loaded environments where discrete particle interactions must be observed within the sampling volume of the laser-produced plasma (LPP). In this study, dry nanoparticles in suspension are generated from a standard solution and sampled in air using Q-switched nanosecond (ns-) pulses, short-focus (SF) femtosecond (fs-) pulses, and filaments. Short time-gated plasma images are captured to observe spatially and temporally varying discrete plasma-particle interactions, which is shown to influence early air breakdown behavior and subsequent plasma evolution. Along with images, photo-multiplier tube (PMT) measurements are conducted where strong spatiotemporal dependencies are exhibited by the collected emission signal on particle proximity and plasma expansion behavior. Finally, conditional analysis is performed on LIBS measurements to determine associated sampling probabilities and filter out spectra with poor or absent emission peaks with an adaptive threshold algorithm. Graphical Abstract This is a visual representation of the abstract. [ABSTRACT FROM AUTHOR]