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Facial symmetry enhances attractiveness, with various therapies available to improve it. However, trends in facial asymmetry remain unclear. This study evaluates the differences between specific facial regions using 3D scanning to guide clinical treatment. The 3dMD face™ system (3dMD Ltd, USA) scanned the faces of 88 participants. Geomagic Wrap 2021 analyzed the left and right sides. Differences in the eyebrow peaks, eyebrow tails, eye ends, and mouth corners were evaluated. Several participants showed a drooping right side of the face in the eyebrow peaks, eyebrow tails, eye ends, mouth corners, tubercula mentale, and mandibular margin positions. A higher proportion had deeper left nasolabial folds and marionette lines, whereas several others had deeper right tear ducts and lateral chin depressions. Several participants exhibited prominent right forehead and parotid masseter region, with prominent left temporal and cheek regions. 3D scanning effectively assesses facial asymmetry in clinical practice. Research indicates significant differences in asymmetry between the facial regions. Evaluating these differences pre-treatment can guide the selection of therapeutic methods to improve facial asymmetry. 3 (Diagnostic). [ABSTRACT FROM AUTHOR]

Background: Cutaneous infections caused by non-tuberculous mycobacteria (NTM) are extremely rare, particularly when they are localized to the facial area. This condition presents significant diagnostic challenges due to its unusual presentation and the need for precise microbiological identification. Case Presentation: A two-year-old male patient presented with a progressively enlarging reddish-brown mass on the left side of his face. Despite the absence of systemic symptoms, the lesion's growth warranted investigation due to its growth. Ultrasonography showed a hypoechoic mass in the dermis, indicating an underlying abscess. The subsequent aspiration resulted in pale yellow pus, which upon testing and culture, confirmed the presence of Mycobacterium avium complex infection, a species of NTM. This case exemplifies the synergy between imaging modalities and microbiological analysis, highlighting the crucial role of both in achieving favorable clinical outcomes in patients with suspected cutaneous NTM infections. Ultrasound can expedite diagnosis, improve treatment planning, and enhance patient care by enabling targeted interventions and monitoring response to therapy in these scenarios. However, it is the combination of pathogen-specific diagnostics that ensures accurate etiological attribution and appropriate antimicrobial stewardship. Conclusion: Although rare, facial cutaneous infections caused by NTM still deserve thorough investigation to determine the exact cause. Ultrasound is used to identify cutaneous lesions, measure their extent, and guide surgical procedures. The ultimate diagnosis is based on microbiological confirmation. [ABSTRACT FROM AUTHOR]

Background: Microbotulinum toxin A treatment is a technique of delivering multiple intradermal injections of diluted botulinum toxin type A into the dermis or the interface between the dermis and the superficial layer of the facial muscles to preserve the facial mobility. The current study aimed to evaluate and compare the clinical effect of different dilutions of microbotulinum toxin A in periorbital and mid-facial rejuvenation. Methods: This randomized prospective interventional study included 30 female patients with different types of wrinkles in periorbital and/or mid-face. Patients were divided into three groups: group I (10 patients): 100U botulinum toxin in 5 ml saline, group II (10 patients): 100U botulinum toxin in 7 ml saline and group III (10 patients): 100U botulinum toxin in 10 ml saline. Results: A statistically significant better global esthetic improvement scale (GAIS) scores after 1 month were observed in group I compared to groups II and III. Also, after 6 months better GAIS scores were observed in group I compared to group II and in group II compared to group III. Assessment of different esthetic parameters measured by the Antera 3D camera revealed a statistically significant improvement in all parameters (periorbital and mid-face) in group I and in most of parameters (periorbital and mid-face) in groups II and III with more evident improvement after 1 month compared to after 6 months. Conclusion: Intradermal microbotulinum toxin A is a cost-effective method for improving periorbital and mid-face wrinkles with a better effect of 1:5 than 1:7 and 1:10 dilutions. Facial wrinkles possess a great burden on patients' psychological status, and the emergence of novel rejuvenation technique with minimal side effects is necessary. MicroBoNT-A usage in the literature was through variety of dilutions and concentrations. Therefore, a conclusive and comparative study was essential to compare the effect of different microBoNT-A dilutions. In this context, the current study aimed to evaluate and compare the clinical effect of different dilutions of microBoNT-A in periorbital and mid-facial rejuvenation. Level of Evidence III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. [ABSTRACT FROM AUTHOR]

Abstract Background Cutaneous infections caused by non-tuberculous mycobacteria (NTM) are extremely rare, particularly when they are localized to the facial area. This condition presents significant diagnostic challenges due to its unusual presentation and the need for precise microbiological identification. Case Presentation A two-year-old male patient presented with a progressively enlarging reddish-brown mass on the left side of his face. Despite the absence of systemic symptoms, the lesion’s growth warranted investigation due to its growth. Ultrasonography showed a hypoechoic mass in the dermis, indicating an underlying abscess. The subsequent aspiration resulted in pale yellow pus, which upon testing and culture, confirmed the presence of Mycobacterium avium complex infection, a species of NTM. This case exemplifies the synergy between imaging modalities and microbiological analysis, highlighting the crucial role of both in achieving favorable clinical outcomes in patients with suspected cutaneous NTM infections. Ultrasound can expedite diagnosis, improve treatment planning, and enhance patient care by enabling targeted interventions and monitoring response to therapy in these scenarios. However, it is the combination of pathogen-specific diagnostics that ensures accurate etiological attribution and appropriate antimicrobial stewardship. Conclusion Although rare, facial cutaneous infections caused by NTM still deserve thorough investigation to determine the exact cause. Ultrasound is used to identify cutaneous lesions, measure their extent, and guide surgical procedures. The ultimate diagnosis is based on microbiological confirmation.

Blaschko-linear pigmented lesions over the face are encountered rarely, and may either be macular or atrophic. A descriptive clinical, dermoscopic, and histopathological analysis of six such cases of hyperpigmented atrophic lesions in a Blaschko-linear distribution that we saw recently in our outpatient department is presented emphasizing the potential of dermoscopy to facilitate prompt management thereby averting cicatrization.

Objective: To assess the effect of vascular loop variant anatomy of anterior inferior cerebellar artery (AICA) types in relation to vestibulocochlear and facial nerves within cerebellopontine angle (CPA) on MRI, in patients presenting with otoneurological symptoms. Study Design: Cross-sectional study. Place and Duration of Study: Combined Military Hospital (CMH) Abbottabad for a period of 8 months from July 01, 2022 to February 28, 2023. Materials and Methods: All patients with audio-vestibular symptoms (group I) pertaining to facial or vestibulocochlear nerve referred for MRI brain were included in the study. Specific MRI protocol for the assessment of cerebellopontine angle and its contents- three-dimensional fast imaging employing steady-state acquisition (3-D FIESTA)- was used to delineate the relation of AICA loop to VII and VIII cranial nerves within cerebellopontine angles and internal auditory meatus on both sides. Patients without any symptoms also underwent similar MR protocol to serve as a control group (group II). Vascular loop anatomy of AICA in CPA was recorded and its relation to patient's symptomatology, if any, was documented. Findings were compared with the control group. Social Package for Statistical Studies (SPSS) version 25.0 was used for analysis. Data type was Qualitative (categorical) and Chi square test was applied for drawing results. A p value of ≤ 0.05 was considered statistically significant with 95% confidence interval (CI). Results: Type I was most common variant in both groups followed by Type II and Type III subsequently. No statistically significant difference was found in the AICA loop variant distribution between the symptomatic and control groups for both right (p = 0.543) and left (p = 0.564) sides with respect to patient's symptoms. Conclusion: AICA loop within cerebellopontine angle demonstrates variant course with respect to internal auditory meatus in proximity to VII and VIII nerves; this variation has no impact on patient's otoneurological symptoms. Other factors need to be addressed and evaluated for such symptoms in the relevant patients.

Abstract Background Idiopathic (IF) and nonidiopathic facial (NIF) nerve palsies are the most common forms of peripheral facial nerve palsies. Various risk factors for IF palsies, such as weather, have been explored, but such associations are sparse for NIF palsies, and it remains unclear whether certain diagnostic procedures, such as contrast agent-enhanced cerebral magnetic resonance imaging (cMRI), are helpful in the differential diagnosis of NIF vs. IF. Methods In this retrospective, monocentric study over a five-year period, the medical reports of 343 patients with peripheral facial nerve palsy were analysed based on aetiology, sociodemographic factors, cardiovascular risk factors, consultation time, diagnostic procedures such as cMRI, and laboratory results. We also investigated whether weather conditions and German Google Trends data were associated with the occurrence of NIF. To assess the importance of doctors’ clinical opinions, the documented anamneses and clinical examination reports were presented and rated in a blinded fashion by five neurology residents to assess the likelihood of NIF. Results A total of 254 patients (74%) had IF, and 89 patients (26%) had NIF. The most common aetiology among the NIF patients was the varicella zoster virus (VZV, 45%). Among the factors analysed, efflorescence (odds ratio (OR) 17.3) and rater agreement (OR 5.3) had the highest associations with NIF. The day of consultation (Friday, OR 3.6) and the cMRI findings of contrast enhancement of the facial nerve (OR 2.3) were also risk factors associated with NIF. In contrast, the local weather, Google Trends data, and cardiovascular risk factors were not associated with NIF. Conclusion The findings of this retrospective study highlight the importance of patient history and careful inspections to identify skin lesions for the differential diagnosis of acute facial nerve palsy. Special caution is advised for hospital physicians during the tick season, as a surge in NIF cases can lead to a concomitant increase in IF cases, making it challenging to choose adequate diagnostic methods.

Background: Idiopathic (IF) and nonidiopathic facial (NIF) nerve palsies are the most common forms of peripheral facial nerve palsies. Various risk factors for IF palsies, such as weather, have been explored, but such associations are sparse for NIF palsies, and it remains unclear whether certain diagnostic procedures, such as contrast agent-enhanced cerebral magnetic resonance imaging (cMRI), are helpful in the differential diagnosis of NIF vs. IF. Methods: In this retrospective, monocentric study over a five-year period, the medical reports of 343 patients with peripheral facial nerve palsy were analysed based on aetiology, sociodemographic factors, cardiovascular risk factors, consultation time, diagnostic procedures such as cMRI, and laboratory results. We also investigated whether weather conditions and German Google Trends data were associated with the occurrence of NIF. To assess the importance of doctors' clinical opinions, the documented anamneses and clinical examination reports were presented and rated in a blinded fashion by five neurology residents to assess the likelihood of NIF. Results: A total of 254 patients (74%) had IF, and 89 patients (26%) had NIF. The most common aetiology among the NIF patients was the varicella zoster virus (VZV, 45%). Among the factors analysed, efflorescence (odds ratio (OR) 17.3) and rater agreement (OR 5.3) had the highest associations with NIF. The day of consultation (Friday, OR 3.6) and the cMRI findings of contrast enhancement of the facial nerve (OR 2.3) were also risk factors associated with NIF. In contrast, the local weather, Google Trends data, and cardiovascular risk factors were not associated with NIF. Conclusion: The findings of this retrospective study highlight the importance of patient history and careful inspections to identify skin lesions for the differential diagnosis of acute facial nerve palsy. Special caution is advised for hospital physicians during the tick season, as a surge in NIF cases can lead to a concomitant increase in IF cases, making it challenging to choose adequate diagnostic methods. [ABSTRACT FROM AUTHOR]

ABSTRACTPain assessment is essential in laboratory and farm animals. Grimace scales have been used for this purpose since 2010. The aim of the present study was to investigate how pain (due to disease presence) affects the main facial expressions of goat kids. For this purpose, 60 goat kids aged 1 to 20 days were included in the study. An experienced veterinarian graded the animals’ pain based on his experience (pain 0, 1, and 2), and two photographs (frontal and lateral) were taken. The following measurements were recorded: Height and width of the palpebral fissure, mouth angle, angles of the nose in profile and front. Pain level affected the height (0.83 and 1.29 cm, pain level 0 and 2 respectively, p

MicroIC enables display attributes unattainable from polycrystalline thin‐film transistors, and the complimentary metal‐oxide semiconductor (CMOS) microICs support a wide range of applications beyond driving pixels. Integrating sensors within displays can add value to products, reduce costs and improve performance versus conventional solutions. As evidenced by touch and display integration in mobile displays via TDDI ICs, in‐cell sensing can reduce cost and improve performance to levels that are not available with all display types. Capacitive touch, optical touch, 3D scanning, and proximity sensing can also benefit from the inherent coordination between sensors and display. We present multiple sensing architectures and demonstrations of integration within microLED displays and describe CMOS microIC circuits for touch sensing applications. With diverse heterogenous semiconductor technology tightly woven into displays, the potential for intuitive gesture controls, adaptive interfaces, and enhanced sensory feedback paves the way for more natural and effortless interactions between humans and machines. [ABSTRACT FROM AUTHOR]

Simple Summary: This study aims to characterize soft tissue tumors/sarcomas (STSs) occurring on the faces of cats using histomorphology, immunohistochemistry, and molecular (PCR) techniques. By examining 34 tumors from 29 cats, we found that many were peripheral nerve sheath tumors (PNSTs), identified by specific protein markers. Interestingly, only a few tumors thought to be sarcoids were confirmed by testing for BPV14. This highlights the need for careful diagnostic methods to correctly identify these tumors. Some tumors appeared as unusual lesions on the face, not typical masses, pointing out an important clue for clinicians. The study also introduces a new observation in tumor cells' pattern and underscores the value of the Sox10 marker in diagnosing PNSTs in cats, offering new insights for veterinary pathologists. Soft tissue tumors/sarcomas (STSs) in felines, encompassing a variety of mesenchymal tumors with similar histomorphological features, present diagnostic challenges due to their diverse cellular origins and the overlap with other tumor types such as feline sarcoid. This study aimed to delineate the clinical, histomorphological, and immunohistochemical characteristics of 34 feline facial spindle cell tumors affecting 29 cats, including testing for bovine papillomavirus type 14 (BPV14), the virus causing feline sarcoids. Only five out of 12 tumors previously diagnosed as feline sarcoids based on histomorphology were confirmed by PCR for BPV14, underscoring the importance of comprehensive diagnostic approaches to accurately distinguish between STSs and feline sarcoids. This study shows that most facial spindle cell tumors were compatible with peripheral nerve sheath tumors (PNSTs) based on positive immunohistochemical staining for Sox10 and other immunohistochemical markers such as GFAP, NSE, and S100. Some of these tumors displayed as multiple independent masses on the face or as erosive and ulcerative lesions without obvious mass formation, an atypical presentation and an important highlight for general practitioners, dermatologists, and oncologists. This study also describes periadnexal whorling of neoplastic cells as a novel histomorphologic finding in feline facial PNSTs and emphasizes Sox10 as a useful complementary immunohistochemical marker for the diagnosis of facial PNST in cats, providing valuable insights for veterinary pathologists. [ABSTRACT FROM AUTHOR]

Introduction: Performing laser hair removal treatments on dark skin is limited by the quantity of melanin within the skin. To minimize side effects, lower values of fluence are selected when using standard 755 or 810 nm diode lasers. However, this approach may limit the effectiveness of the procedure, particularly when treating areas with thin and less pigmented hair, which is often the case in facial regions. To improve results, high‐power triple wavelength diode lasers can be used. This study aims to assess the efficacy, safety, and comfort of treatments that remove facial hair with a high‐power triple wavelength diode laser (810, 940, and 1060 nm) in static mode on Asian patients with thin and less pigmented hair. Materials and Methods: A single‐center retrospective cohort study was carried out using a high‐power triple wavelength diode laser (810, 940, and 1060 nm), with a 2.7 cm2 spot size, on faces with thin and less pigmented hair. The study comprised 23 subjects with Fitzpatrick skin types IV and V. Effectiveness was measured by counting the hairs that appeared in high‐resolution photos taken prior to and following the procedure, in addition to the Global Aesthetic Improvement Scale (GAIS). Furthermore, mathematical 3D simulations were created on the COMSOL Multiphysics® software to allow for comparisons to be made with regard to thermal damage sustained by the hair follicles and epidermal heating. Assessments were also made in relation to side effects. Results: An average of 66% hair reduction was observed. Patient satisfaction was between 4 and 5 points on the GAIS scale, indicating that the treatment was very well received and tolerated. Adverse side effects were not observed. Conclusion: It can be concluded that the use of a high‐power triple wavelength diode laser (810, 940, and 1060 nm) is safe and effective for the treatment of very fine and less pigmented facial hair on Asian skin. Furthermore, a triple wavelength (810, 940, and 1060 nm) laser is absorbed less by the melanin in the skin, enabling the use of higher fluences in stamping mode, with greater efficacy and safety for darker skin. [ABSTRACT FROM AUTHOR]

Background: Hyaluronic acid (HA) dermal fillers are widely used in aesthetic medicine. While generally safe, potential complications can arise. Objective: This systematic review aims to identify and classify potential complications linked to the use of HA dermal fillers, as informed by high-quality, low-risk-of-bias studies. Methods: This review follows the Cochrane review standards for clinical systematic reviews. This systematic review analyzed 48 high level of evidence studies on the use of hyaluronic acid (HA) dermal fillers in non-surgical facial aesthetics and the adverse events that occurred.The inclusion criteria were randomized control studies on HA dermal fillers and their complications. Excluded were case reports, case series, observational studies, and other non-randomized research due to their inability to provide generalized conclusions and their inherent publication bias. Results: Adverse events were classified into three categories: expected reactions, product or technique-related adverse events, and severe adverse events. Most adverse events were short-lived injection site reactions, which resolved spontaneously. Specific HA fillers and injection techniques influenced the occurrence of adverse events, which generally resolved within weeks without treatment. Severe adverse events were rare, persisting for months and requiring active medical intervention. Discussion: This classification system can enhance understanding, prevention, and treatment of HA filler complications, and support patient education. The common complications were injection site reactions, with persistent symptoms treated with topical steroids, NSAIDs, or hyaluronidase. Severe complications included severe edema, angioedema and others, often necessitating specific treatments. Conclusion: HA dermal fillers are generally safe and effective, with most adverse events being transient and mild to moderate in severity. Severe adverse events, although rare, do occur and are generally non-treatment related. Informed consent, patient education, and professional training are crucial for safe and successful outcomes. Level of Evidence II This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. [ABSTRACT FROM AUTHOR]

The evaluation of maxillary teeth and soft tissue profiles is a critical component of orthodontic diagnosis and treatment planning. This study aimed to evaluate the correlation between the sagittal position of maxillary anterior teeth and facial profile esthetics among Tibetan and Han Chinese adult females for optimizing orthodontic diagnosis and treatment planning. A total of 100 Tibetan Chinese and 100 Han Chinese adult females with good facial symmetry were recruited. The smiling facial profile images with the maxillary central incisors and forehead in full view were taken based totally on the same standard. The photo measurement and head position were adjusted using the picture-enhancing software. The reference traces associated with forehead inclinations were utilized to assess the anteroposterior (AP) positions of the maxillary central incisors. The results showed that a round forehead was the dominant forehead shape for Tibetan (93%) and Han (55%) Chinese females. In Tibetan females, 85% of the maxillary central incisors were found to be located between the forehead's anterior limit line (the Gall line) and the goal anterior limit line (the Fall line), with 15% located posterior to the Fall line. This distribution manifested a strong association with incisor position and forehead inclination (R2 = 0.742). In Han females, 83% of the maxillary central incisors were located between the Fall line and the Gall line, with 12% posterior to the Fall line and 5% anterior to the Gall line. The positions of the maxillary central incisors exhibited a strong relationship with forehead inclination (R2 = 0.827). The maxillary central incisors were close to the aesthetic line in both ethnic groups, while forehead inclinations were correlated with AP maxillary incisor position. These findings demonstrated that there was a close relationship between the incisor position of Tibetan and Han females with facial symmetry and the forehead FFA factor, indicating a reference in oral hard and soft tissues for optimizing orthodontic diagnosis and treatment planning in terms of facial contour.

Facial privacy is essential in our time due to the violations that occur due to the proliferation of social media and people's primary dependence on it. Facial features can be exploited to identify, track, or other matters without obtaining prior consent. This is increasingly important due to the increasing use of facial recognition technologies. Protecting the face and privacy is a challenging task, as the entire world is very widely connected through social networking sites in an uncensored manner, especially in countries with no electronic governance or oversight. Therefore, there is an urgent need to provide systems or research that focuses on the issue of facial privacy. In this paper, a system for providing privacy for people was proposed using the WIDER FACE data set, considered the most important among the data sets. The system aims to provide privacy for people by determining the destination that must be preserved and provided with privacy through three technical. The approach goes through several steps: The processing process of the image is achieved by enhancement of the images that are input in the training stage and then dividing the data into a test and training set, and the training stage through the YOLOv6 algorithm (looks only once), and privacy operations including encryption, decryption, mask and blurring in the test part of the data, and conducting an external test for personal photo. The final results of the proposed system were as follows: accuracy = 0.98 in training and 0.96 in testing.

Facial privacy is essential in our time due to the violations that occur due to the proliferation of social media and people's primary dependence on it. Facial features can be exploited to identify, track, or other matters without obtaining prior consent. This is increasingly important due to the increasing use of facial recognition technologies. Protecting the face and privacy is a challenging task, as the entire world is very widely connected through social networking sites in an uncensored manner, especially in countries with no electronic governance or oversight. Therefore, there is an urgent need to provide systems or research that focuses on the issue of facial privacy. In this paper, a system for providing privacy for people was proposed using the WIDER FACE data set, considered the most important among the data sets. The system aims to provide privacy for people by determining the destination that must be preserved and provided with privacy through three technical. The approach goes through several steps: The processing process of the image is achieved by enhancement of the images that are input in the training stage and then dividing the data into a test and training set, and the training stage through the YOLOv6 algorithm (looks only once), and privacy operations including encryption, decryption, mask and blurring in the test part of the data, and conducting an external test for personal photo. The final results of the proposed system were as follows: accuracy = 0.98 in training and 0.96 in testing. [ABSTRACT FROM AUTHOR]

The nationwide extension of the electric scooter (e-scooter) scheme, which began in 2020, aimed to alleviate public transport congestion, to reduce pollution and peak-time road traffic. This retrospective study evaluates the range of e-scooter-related maxillofacial trauma before the recent scheme extension and compares the findings with existing literature on this topic. The Queen Elizabeth Hospital Birmingham, United Kingdom (UK) operates as a Level 1 Regional Major Trauma Centre and serves a population of four million. All patient records between September 2021 to September 2022 were analysed to establish the types of e-scooter-related maxillofacial trauma sustained. A Pearson's chi-squared test was used to assess for significant associations between variables recorded. Falls accounted for the majority of injuries (44.3%), and soft tissue lacerations were the most common maxillofacial injury (38%). Statistically significant results were measured in the following variables: gender and intoxication status (p = 0.007), helmet status and injuries sustained in maxillofacial and non-maxillofacial regions (p = 0.043), mechanism of injury and injuries sustained in both the maxillofacial and non-maxillofacial regions (p = 0.045). E-scooters are an emerging concern within the UK. Further studies across the UK are required to assess the frequency of e-scooter-related injuries. Such data may prove useful in determining the government's decision on e-scooter use on UK roads. [ABSTRACT FROM AUTHOR]

Smart, intelligent and automated environments solves real-world issues by modeling artificial intelligence based applications. AI such as functional, analytical, textual and visual AI are applied to enhance capabilities and intelligence of an application. Information security is significant in the field of information technology. AI-powered biometric solutions have initiated to flourish in securing individual's identification to combat unauthorized access. Security deals with authentication; biometric user authentication systems should adopt reliable schemes to determine or confirm individual's identity who seek services. Such schemes should render service to only legitimate users to access secured environments. Face Detection and Recognition is emerging as ideal solution to facilitate secure verification and authentication in secured systems. In this paper, Siamese Neural Network method which employ unique structure is adopted to naturally rank input similarities of Biometric traits. The network is tuned to benefit from dominant discriminative features for generalizing predictions in authority of all new classes from unfamiliar distributions. Proposed approach for face recognition is compared with few current state-of-the-art approaches. The approach achieved an accuracy of 96.5%. Novelty of the research lies in combining Siamese network and Biometric authentication. [ABSTRACT FROM AUTHOR]

Reticulohistiocytoma is a localized form of reticulohistiocytosis without systemic involvement. This is a histiocytic reactive lesion which can arise on the skin or mucosa. A 60-year-old female presented with an ill-defined solitary reddish brown, firm, nontender nodule of size 1.5 × 1.5 cm, lateral to right nasolabial fold for 1 year. Histopathological examination showed irregular acanthosis in the epidermis and the dermis revealed collection of histiocytes in clusters, some of which showed eosinophilic cytoplasm which was suggestive of a benign histiocytic lesion. Immunohistochemistry showed scattered cell positivity for CD68 and S100. A final diagnosis of solitary adult onset reticulohistiocytoma was made and an elliptical excision was done. There is a need for clinicopathological correlation along with immunohistochemistry to diagnose this entity and differentiate from other mimickers. Reported cases of facial reticulohistiocytoma, of which two were reported from India, have been reviewed for a better understanding of this entity. [ABSTRACT FROM AUTHOR]

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare primary cutaneous lymphoma which often be very complexed to be diagnosed. Here we reported a case of a 38-year-old lady with wax and wane course of left facial swelling associated with prolonged pyrexia of unknown origin, lethargy and prominent weight loss. Multiple investigations were conducted to reach to the conclusive diagnosis. Histopathological showed infiltration of neoplastic lymphoid cells within the adipocyte clusters with hyperchromatic nuclei, small nucleoli and scant cytoplasm. Immunohistochemical analysis were immunoreactive to CD3, CD8 & TIA and negative to CD20, CD4 & CD56. Based on clinical findings, histopathology report and immunohistochemical analysis, the patient diagnosed with SPTCL. Hence, any suspicious maxillofacial swelling without obvious sign of infection and trauma shall be investigated until a final diagnosis is reached. [ABSTRACT FROM AUTHOR]

Facial palsy (FP) is a known consequence of head trauma, manifesting either immediately at the time of injury or with delayed onset, typically occurring 2 days or more post-trauma. Unilateral FP is the more common presentation and is often attributed to partial or complete transection of facial nerves or delayed onset edema. Conversely, bilateral facial palsy is a rare occurrence, reported in only a small number of cases, accounting for approximately 3% of patients presenting with bilateral weakness. In this report, we present the case of a previously healthy 28-year-old female who suffered a closed head injury during the Beirut Port Blast. Four days following the incident, the patient exhibited right-sided peripheral FP, which was consistent with a right temporal bone fracture. Subsequently, on the fifth day, the right-sided FP worsened, accompanied by the development of new FP on the left side, characterized by sparing of the frontal region, indicating a central origin for the left-sided FP. Laboratory investigations revealed severe hypovolemic hyponatremia with a sodium level of 105 mmol/L. As isotonic saline fluid replacement was initiated, there was progressive improvement in the left-sided FP. The right-sided palsy also resolved gradually with the implementation of facial rehabilitation therapy. It is important to note that severe head trauma, particularly with a concussive injury, can lead to facial paralysis through various mechanisms. Furthermore, severe hyponatremia should be considered a potential cause of central facial palsy, particularly in the presence of bilateral facial involvement. A thorough evaluation is encompassing assessment of palsy patterns, comprehensive imaging studies, and metabolic investigations is crucial for accurate diagnosis and timely intervention, resulting in successful treatment.

The article titled "Adverse Events Associated with Hyaluronic Acid Filler Injection for Non-surgical Facial Aesthetics: A Systematic Review of High Level of Evidence Studies" by Kyriazidis et al.in Aesthetic Plastic Surgery presents a systematic review focused on categorizing complications linked to hyaluronic acid (HA) dermal fillers. However, concerns arise about the methodologies employed in the reviewed studies. Precise knowledge of the active substance's properties is vital for treatment standardization. Gaining a comprehensive understanding of the key characteristics of the employed HA is of paramount importance to ascertain whether an association exists between these properties and the risk of complications. Understanding the rheological properties of HA, including viscosity, elasticity, and cohesiveness, is crucial for optimal facial filler selection. Acknowledging the authors' contributions, further analysis should encompass these factors. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266. [ABSTRACT FROM AUTHOR]

Headache and facial pain are common complaints for which patient visits otorhinolaryngologist. Many patients have a misconception that all types of headache are sinus related and incorrectly refer it as sinus headache. It is the duty of an otorhinolaryngologist to correctly differentiate between sinogenic and nonsinogenic causes of headache/facial pain through proper history taking, diagnostic nasal endoscopy, radiological investigation to reach at an appropriate diagnosis. In this article various sinogenic and non sinogenic causes of headache are briefly discussed. A proper knowledge of diagnostic criteria of different types of headache will ensure correct and timely treatment of the patient and improve patient satisfaction.

Abstract Objective The aim of this review article is to discuss the currently available facial fillers, their differences and indications, relevant anatomy, injection techniques, and avoidance and management of complications. Data Sources Clinical experience and scientific papers. Conclusions Reversal of facial aging via filler injection has been around since the late 1800s with the initial use of detrimental products. Today, many safe and effective products exist and can be tailored to the individual patient's desired effect. With the evolution of both products and injection techniques, the rate of complications with facial filler use is low. Nonetheless, providers offering facial filler injections should have detailed knowledge of facial anatomy, including facial planes and soft tissue compartments. Multiple injection techniques exist. Different techniques should be used, depending on the anatomic target. Providers should also know how to avoid and manage complications.

Abstract Background The purpose of this study was to evaluate the pattern of predicted interosseous interference and to determine the influencing factor to volume of bony interference using a computer-assisted simulation system. This retrospective study recruited 116 patients with mandibular prognathism who had undergone sagittal split ramus osteotomy (SSRO) with or without maxillary osteotomy. The patients were divided into 3 groups according to the amount of menton (Me) deviation: less than 2 mm (Group 1), 2–4 mm (Group 2), and more than 4 mm (Group 3). Changes in the distal segments following BSSRO and the volume of the interosseous interference between the proximal and distal segments were simulated after matching preoperative occlusion and postoperative expected occlusion with the cone-beam computed tomography data. Ramal inclinations and other skeletal measurements were analyzed before surgery, immediately after surgery, and at least 6 months after surgery. Results The anticipated interosseous interference was more frequently noted on the contralateral side of chin deviation (long side) than the deviated site (short side) in Groups 2 and 3. More interference volume was predicted at the long side (186 ± 343.9 mm3) rather than the short side (54.4 ± 124.4 mm3) in Group 3 (p = 0.033). The bilateral difference in the volume of the interosseous interference of the osteotomized mandible was significantly correlated with the Me deviation (r = − 0.257, p = 0.009) and bilateral ramal inclination (r = 0.361, p

Aim of the Study Mucormycosis is a rare invasive and fatal fungal infection and its resurgence in coronavirus disease 2019 (COVID-19) patients has been a matter of grave concern. It is essentially a medical disease, but surgical debridement of necrotic tissues is of paramount importance leading to severe craniofacial deformities. In this case series, we present our experience with the feasibility of early reconstruction after surgical debridement.

Purpose: To perform a systematic review of literature specific to single-fraction stereotactic radiosurgery (SRS) for large vestibular schwannomas (VS), maximum diameter ≥ 2.5 cm and/or classified as Koos Grade IV, and to present consensus recommendations on behalf of the International Stereotactic Radiosurgery Society (ISRS). Methods: The Medline and Embase databases were used to apply the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) approach. We considered eligible prospective and retrospective studies, written in the English language, reporting treatment outcomes for large VS; SRS for large post-operative tumors were analyzed in aggregate and separately. Results: 19 of the 229 studies initially identified met the final inclusion criteria. Overall crude rate of tumor control was 89% (93.7% with no prior surgery vs 87.7% with prior surgery). Rates of salvage microsurgical resection, need for shunt, and additional SRS in all series versus those with no prior surgery were 9.6% vs 3.3%, 4.7% vs 6.4% and 1% vs 0.9%, respectively. Rates of facial palsy and hearing preservation in all series versus those with no prior surgery were 1.3% vs 3.4% and 34.2% vs 40.4%, respectively. Conclusions: Upfront SRS resulted in high rates of tumor control with acceptable rates of facial palsy and hearing preservation as compared to the results in those series including patients with prior surgery (level C evidence). Therefore, although large VS are considered classic indication for microsurgical resection, upfront SRS can be considered in selected patients and we recommend a prescribed marginal dose from 11 to 13 Gy (level C evidence). [ABSTRACT FROM AUTHOR]

Abstract Objective To perform a review evaluating management of and complications stemming from dog bite trauma sustained to the head and neck over the past decade. Data Sources PubMed and Cochrane Library. Methods The authors searched the PubMed and Cochrane Library databases for relevant published literature. A total of 12 peer‐reviewed canine‐exclusive series inclusive of 1384 patient cases describing facial dog bite trauma met inclusion criteria. Wounds including fractures, lacerations, contusions, and other soft‐tissue injuries were evaluated. Demographics related to clinical course and management, operating room requirements, and antibiotic usage were compiled and analyzed. Initial trauma and surgical management complications were also assessed. Results 75.5% of patients sustaining dog bites required surgical intervention. Of these patients, 7.8% suffered from postsurgical complications, including hypertrophic scarring (4.3%), postoperative infection (0.8%), or nerve deficits and persistent paresthesias (0.8%). Prophylactic antibiotics were administered to 44.3% of patients treated for facial dog bites and the overall infection rate was 5.6%. Concomitant fracture was present in 1.0% of patients. Conclusion Primary closure, often in the OR may be necessary, with few cases requiring grafts or flaps. Surgeons should be aware that the most common complication is hypertrophic scarring. Further research is needed to elucidate the role of prophylactic antibiotics.

Soft tissue tumors/sarcomas (STSs) in felines, encompassing a variety of mesenchymal tumors with similar histomorphological features, present diagnostic challenges due to their diverse cellular origins and the overlap with other tumor types such as feline sarcoid. This study aimed to delineate the clinical, histomorphological, and immunohistochemical characteristics of 34 feline facial spindle cell tumors affecting 29 cats, including testing for bovine papillomavirus type 14 (BPV14), the virus causing feline sarcoids. Only five out of 12 tumors previously diagnosed as feline sarcoids based on histomorphology were confirmed by PCR for BPV14, underscoring the importance of comprehensive diagnostic approaches to accurately distinguish between STSs and feline sarcoids. This study shows that most facial spindle cell tumors were compatible with peripheral nerve sheath tumors (PNSTs) based on positive immunohistochemical staining for Sox10 and other immunohistochemical markers such as GFAP, NSE, and S100. Some of these tumors displayed as multiple independent masses on the face or as erosive and ulcerative lesions without obvious mass formation, an atypical presentation and an important highlight for general practitioners, dermatologists, and oncologists. This study also describes periadnexal whorling of neoplastic cells as a novel histomorphologic finding in feline facial PNSTs and emphasizes Sox10 as a useful complementary immunohistochemical marker for the diagnosis of facial PNST in cats, providing valuable insights for veterinary pathologists.

Abstract A 69‐year‐old man was referred for a necrotic lesion on the nose suggestive of bacterial infection. The patient had a HIV‐positive status with normal CD4+ T‐cell count and undetectable viral load. Despite antibiotic treatment, the lesion expanded, and vesiculopustular lesions appeared on the legs and hands. Monkeypox infection was diagnosed by polymerase chain reaction of swabs obtained from lesions on the hands and nose. This unusual presentation, suggestive of bacterial cellulitis of the face, highlights the importance of extra‐genital presentations of Monkeypox infection.

Objective: To describe the epidemiological, diagnostic and therapeutic aspects of odontogenic cervicofacial cellulitis in rural Togo, and more specifically in the town of Dapaong. Method: This was a monocentric, retrospective, descriptive study conducted at the Dapaong regional hospital over 03 years from January 2019 to December 2021. Results: A total of 103 cases were collected, representing an annual frequency of 34.33 cases per year. The mean age of the patients was 45.69 ± 17.49 years. We reported a male predominance, with a male/female sex ratio of 2.03. We had high exposure to risk factors for cervicofacial cellulitis (92.23%), with HIV infection predominating. Anti-inflammatory drugs and traditional therapy concerned 43.68% and 48.54% of our sample respectively. The average consultation time was 16.17 ± 7.42 days. Pain (100%) and swelling (84.46%) were the clinical signs most frequently encountered. Involvement was predominantly hemifacial, with diffuse cellulitis predominating (56.31%). The maxillary molars (38.83%) were the main site of infection. Resuscitation and triple antibiotic therapy concerned 23.30% of patients, and surgery 59.22%. The in-hospital mortality rate for odontogenic cervicofacial cellulitis in our study was 11.65%. Conclusion: Although odontogenic cervicofacial cellulitis is uncommon in the town of Dapaong, it is associated with a delay in treatment and a high mortality rate.

Background: The purpose of this study was to evaluate the pattern of predicted interosseous interference and to determine the influencing factor to volume of bony interference using a computer-assisted simulation system. This retrospective study recruited 116 patients with mandibular prognathism who had undergone sagittal split ramus osteotomy (SSRO) with or without maxillary osteotomy. The patients were divided into 3 groups according to the amount of menton (Me) deviation: less than 2 mm (Group 1), 2–4 mm (Group 2), and more than 4 mm (Group 3). Changes in the distal segments following BSSRO and the volume of the interosseous interference between the proximal and distal segments were simulated after matching preoperative occlusion and postoperative expected occlusion with the cone-beam computed tomography data. Ramal inclinations and other skeletal measurements were analyzed before surgery, immediately after surgery, and at least 6 months after surgery. Results: The anticipated interosseous interference was more frequently noted on the contralateral side of chin deviation (long side) than the deviated site (short side) in Groups 2 and 3. More interference volume was predicted at the long side (186 ± 343.9 mm3) rather than the short side (54.4 ± 124.4 mm3) in Group 3 (p = 0.033). The bilateral difference in the volume of the interosseous interference of the osteotomized mandible was significantly correlated with the Me deviation (r = − 0.257, p = 0.009) and bilateral ramal inclination (r = 0.361, p < 0.001). The predictor variable that affected the volume of the osseous interference at each side was the amount of Me deviation (p = 0.010). Conclusion: By using the 3D simulation system, the potential site of bony collision could be visualized and successfully reduced intraoperatively. Since the osseous interference can be existed on any side, unilaterally or bilaterally, 3D surgical simulation is necessary before surgery to predict the osseous interference and improve the ramal inclination. [ABSTRACT FROM AUTHOR]

Facial blast injuries in gold panning are rarely reported in the literature. The aim of this paper is to describe the epidemiological and clinical presentations of facial blast injuries in gold panning in Burkina Faso. The medical records of patients suffering from facial blast injuries in gold panning sites between January 2017 and December 2020 were analyzed retrospectively. Data recording and analysis were performed with Epi Info 7 software. Facial blast injuries in gold panning represented 3.1 % of all facial trauma. The patients were all male with a mean age of 26.8 years. Soft tissue injuries accounted for 44.2 % of facial injuries. Two-thirds of the wounds were skin screening. Facial fractures accounted for 23 % of injuries. They were a multiple fracture in 4 patients. Monocular and binocular blindness were observed with equal frequency, each in 7 patients. Associated injuries were hand dislocations in 31 patients, thoracic limbs fractures in 5 patients, lower limbs fractures in 6 patients and perforation of the eardrum in 1 patient. These results call for a strengthening of the laws governing the use of explosives, and a rigorous supervision of artisanal gold panning in Burkina Faso. [ABSTRACT FROM AUTHOR]

Dyspigmentation is a common cosmetic concern in dermatology. Currently, the first line topical medication in the United States is hydroquinone. Hydroquinone use is associated with potential safety concerns including cytotoxicity to melanocytes, systemic absorption, metabolism in distant organs, and production of potentially carcinogenic metabolites. Hexylresorcinol is an ingredient that has been used in food preservation and as antiseptic has been shown to inhibit tyrosinase in vitro and has been studied as a novel skin-lightening agent. To perform a double-blind randomized split-body investigation of comparison on topical hexylresorcinol and hydroquinone on face and hands to assess for change in the appearance of skin tone and pigmentation. Thirty-two healthy female participants ages 35–65 (50.93 ± 7.37) years old with skin type I–IV were randomized to using either topical 1% hexylresorcinol or 2% hydroquinone on the left or right side of the face and corresponding hand over 12 weeks. The topical preparation was applied twice a day to assigned areas. Standardized photos were taken of the face and colorimetric measurements were taken of both sides of the forehead, cheeks and each hand at baseline (Day 0), week 4, and week 12. Of the 32 participants, 3 were lost to follow-up and the remaining were included in the final analysis. Pigmentation measured by colorimeter and clinical grading were significantly decreased at 4 and 12 weeks relative to baseline with no difference between the HR and HQ groups. No adverse effects were noted with either intervention. Hexylresorcinol 1% is well-tolerated and equivalent to hydroquinone 2% in reducing the appearance of facial and hand pigment. Further studies with an expanded population and longer time course are warranted. Registration No.: NCT04345094. [ABSTRACT FROM AUTHOR]

Objective: To investigate microanatomic organizations of the extratemporal facial nerve and its branches, hypoglossal nerve, sural nerve, and great auricular nerve. Methods: Nerve samples were dissected in 12 postmortem autopsies, and histomorphometric analyses were conducted. Results: There was no significant difference between the right and left sides of the nerve samples for the nerve area, fascicle area, number of fascicles and average number of axons. The lowest mean fascicle number was found in the hypoglossal nerve (4.9 ± 1.4) while the highest was in great auricular nerve (11.4 ± 6.8). The highest nerve area (3,182,788 ± 838,430 μm2), fascicle area (1,573,181 ± 457,331 μm2) and axon number (14,772 ± 4402) were in hypoglossal nerve (p