1. Comparative performance of vulvovaginal swab sampling versus endocervical sampling for the detection of Chlamydia, Gonorrhea, Mycoplasma genitalium, and Trichomoniasis: a cross-sectional study in Spain.
- Author
-
Linares M, Galicia P, Rojas A, Miguel-Benito A, Cuadros-González J, and Ramos-Rincón JM
- Subjects
- Humans, Female, Cross-Sectional Studies, Retrospective Studies, Adult, Spain, Young Adult, Mycoplasma Infections diagnosis, Sensitivity and Specificity, Cervix Uteri microbiology, Cervix Uteri pathology, Vaginal Smears, Vagina microbiology, Middle Aged, Trichomonas Infections diagnosis, Adolescent, Sexually Transmitted Diseases diagnosis, Sexually Transmitted Diseases microbiology, Gonorrhea diagnosis, Chlamydia Infections diagnosis, Mycoplasma genitalium isolation & purification, Specimen Handling methods
- Abstract
Introduction: The global increase in sexual transmitted infections (STI) makes it necessary to seek public health strategies that facilitate rapid and minimally invasive diagnosis. The objective was to evaluate the concordance between vaginal and endocervical samples for STI diagnosis., Materials and Methods: A retrospective cross-sectional study was carried out on vaginal and endocervical samples from women attended in our reference area with symptoms suggestive of vulvovaginitis or for STI screening during the study period., Results: A total of 130 paired samples were analyzed; fifty-seven and 59 samples were positive for vaginal and endocervical specimens (Kappa index of 0.969 (Standard error = 0.022). The sensitivity of the vaginal samples was 96.5% (IC95%: 87.2-99.4), with a specificity of 100% (IC95%: 93.0-100)., Discussion: The introduction of STI screening in vaginal samples in our environment can facilitate rapid and effective diagnosis and allow early treatment of STI. Additionally, it facilitates sample collection and diagnosis in the community setting, essential for optimal screening., (Copyright © 2024 Elsevier España, S.L.U. and Sociedad Española de Medicina Interna (SEMI). All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF