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Background and Objectives: Diffusion of hydroxide (OH)− and calcium (Ca)++ ions through dentin may cease external root resorption. Calcium hydroxide (Ca(OH)2), mineral trioxide aggregate (MTA), and calcium‐enriched mixture (CEM) cement are the choices for this purpose due to their optimal properties. This study sought to analyze the effects of ultrasonic activation (UA) on pH and the release of calcium ions from Ca(OH)2, MTA, and CEM cement in external root resorption artificial defects. Materials and Methods: This in vitro research involved the instrumentation and shaping of the root canals of 150 single‐rooted teeth (#F4). External defects were intentionally made on the middle one‐third of the root surface. Teeth were randomly assigned to a negative control group (n = 10), one positive control group (n = 20), and six experimental groups (each n = 20) according to the root canal filling material (Ca(OH)2 paste, MTA, CEM, gutta‐percha, Ca(OH)2 paste+ultrasonic, MTA + ultrasonic, and CEM + ultrasonic). Ultrasonic energy was transferred to the test materials using a #25 spreader. Ca++ concentration and pH were measured after 1, 7, 15, and 30 days in all groups. Statistical analysis involved the use of repeated measure analysis of variance (ANOVA) and paired‐sample T‐test (P ≤ 0.05). Results: The levels of calcium ions and pH increased significantly over time in all groups (P < 0.001). There were significant differences between the experimental groups in terms of pH and the concentration of released calcium ions at different times (P < 0.001). The Ca(OH)2 plus ultrasonic energy group ranked first, while the gutta‐percha group ranked last in terms of release of calcium ions and pH. Conclusion: The Ca(OH)2, MTA, and CEM cement groups showed an increase in pH and the release of calcium ions at the external root resorption defects. Additionally, the application of ultrasonic energy increased the release of calcium ions at these sites. [ABSTRACT FROM AUTHOR]

Objective: The objective of this study was to evaluate external apical root resorption (EARR) in cases with extraction and non-extraction fixed orthodontic treatment. Methods: Ninety subjects were included in this study. The patients were divided into two groups: 43 with extraction treatment and 47 with non-extraction orthodontic treatment. EARR was measured using the crown-to-root ratio of the maxillary and mandibular incisors and canines on panoramic radiographs taken at the beginning (T0) and end of the treatment (T1). The Bonferroni corrected Z test was used for multiple comparisons. Results: There were 24 (55.8%) individuals in the extraction group and 12 (25.5%) in the non-extraction group, with a minimum of one tooth with severe resorption. There was no resorption in 0% of individuals in the extraction group and five (10.6%) individuals in the non-extraction group. There was a statistically significant correlation between the groups and the degree of resorption (p = 0.008). When the maxillary and mandibular teeth in the extraction group were compared, a significant difference was found in all degrees of resorption except for mild resorption. Conclusions: There was a significant difference in EARR between the extraction and non-extraction treatment groups, with maxillary incisors showing more resorption in the extraction treatment. [ABSTRACT FROM AUTHOR]

Introduction: Orthodontic treatment of severe Bi-maxillary protrusion cases involves extractions of all four premolars to provide space for anterior teeth retraction. Over the years different methods of retraction have been developed for individual tooth retraction and en-masse anterior teeth retraction utilising different types of mechanics for retraction purposes. Anchorage consideration has been a problem because of anchor loss, but it has been overcome by utilising absolute anchorage with Temporary Anchorage Devices (TAD). Need for the study: The TAD devices mini plates and mini-screw have been Known for providing absolute anchorage for retraction purposes but there has been limited evidence to prove which TAD device is better in terms of time taken for retraction and external root resorption. Therefore, the present clinical study aims to determine the superior treatment method using the two devices based on duration in terms of time taken and amount of retraction achieved in the specified time. Aim: Evaluation and comparison of the effectiveness of mini-plate and mini-screw for retraction of anterior teeth in severe bimaxillary protrusion cases with extraction of Ist bicuspids. Materials and Methods: A split-mouth randomised controlled trial will be carried out in the Department of Orthodontics and Dentofacial Orthopedics, Sharad Pawar Dental College and Hospital, Sawangi, Wardha, from October 2024 to March 2026 with a total of 11 subjects. The sample will be selected from the Outpatient Department based on the study’s inclusion and exclusion criteria. Informed written consent will be gathered from all participants. The patient sample will be divided into two groups: Group-A: will receive a mini screw (control group) and Group-B: will receive a mini-plate (experimental group). The statistical analysis for comparing the en-mass rate of retraction of anterior teeth (mm) in the allocated groups will be done using the Mann-Whitney test, and student’s t-test, with the significance level set at 5%.

Treatment of external root resorption (ERR) and accompanying periodontal abnormalities can be problematic for the majority of clinicians. When managing cases involving both ERR and osseous defects, it is essential to address both aspects comprehensively. Treatment strategy may include periodontal therapy to address the osseous defect and stabilize the surrounding bone, along with endodontic intervention to manage root resorption and preserve tooth structure. This case report describes the use of a multidisciplinary strategy in treating endodontic-periodontal lesions with ERR affecting the prognosis of the tooth in a 50-year-old male. Endodontic lesion was managed by performing root canal treatment, periodontal defect was regenerated using a xenograft material, and the ERR was treated with mineral trioxide aggregate. The results obtained in this interdisciplinary case remained stable for over 6 months. [ABSTRACT FROM AUTHOR]

Introduction: Orthodontic treatment of severe Bi-maxillary protrusion cases involves extractions of all four premolars to provide space for anterior teeth retraction. Over the years different methods of retraction have been developed for individual tooth retraction and en-masse anterior teeth retraction utilising different types of mechanics for retraction purposes. Anchorage consideration has been a problem because of anchor loss, but it has been overcome by utilising absolute anchorage with Temporary Anchorage Devices (TAD). Need for the study: The TAD devices mini plates and miniscrew have been Known for providing absolute anchorage for retraction purposes but there has been limited evidence to prove which TAD device is better in terms of time taken for retraction and external root resorption. Therefore, the present clinical study aims to determine the superior treatment method using the two devices based on duration in terms of time taken and amount of retraction achieved in the specified time. Aim: Evaluation and comparison of the effectiveness of miniplate and mini-screw for retraction of anterior teeth in severe bimaxillary protrusion cases with extraction of Ist bicuspids. Materials and Methods: A split-mouth randomised controlled trial will be carried out in the Department of Orthodontics and Dentofacial Orthopedics, Sharad Pawar Dental College and Hospital, Sawangi, Wardha, from October 2024 to March 2026 with a total of 11 subjects. The sample will be selected from the Outpatient Department based on the study's inclusion and exclusion criteria. Informed written consent will be gathered from all participants. The patient sample will be divided into two groups: Group-A: will receive a mini screw (control group) and Group-B: will receive a mini-plate (experimental group). The statistical analysis for comparing the en-mass rate of retraction of anterior teeth (mm) in the allocated groups will be done using the Mann-Whitney test, and student's t-test, with the significance level set at 5%. [ABSTRACT FROM AUTHOR]

Abstract Background Entirely impacted mandibular third molar (EIM3M) concerns the pathological external root resorption (ERR) of the adjacent mandibular second molar (M2M) and formation of granulation tissue between two molars. The study aimed to clarify the effect of αENaC, a mechano-sensitive molecule, to explore the mechanical mechanism in this scenario. Methods The force EIM3M exerted on M2M was proved by finite element analysis. αENaC expressions were tested by real-time polymerase chain reaction (PCR), immunoblotting and immunofluorescence. Inflammatory and epithelial-mesenchymal transition (EMT)-related molecules expressions were also detected by real-time PCR. The correlation was analyzed by Spearman’s correlation analysis, and receiver-operator characteristic (ROC) curve was further exhibited. Results The force was concentrated in the ERR area. αENaC was upregulated, positively correlated with ERR degree and localized to the fibroblasts in ERR granulation tissues. Moreover, αENaC was respectively and positively associated with elevated TNF-α and N-cadherin in ERR granulation tissues. More importantly, ROC analysis verified αENaC as a novel indication of the incidence of this disease. Conclusions Our finding revealed the force from EIM3M causing ERR of M2M, and elucidated the expression and localization of αENaC and its positive correlation with inflammation, EMT and disease severity, suggesting a novel indication in this disease.

Abstract Background Artificial intelligence has been proven to improve the identification of various maxillofacial lesions. The aim of the current study is two-fold: to assess the performance of four deep learning models (DLM) in external root resorption (ERR) identification and to assess the effect of combining feature selection technique (FST) with DLM on their ability in ERR identification. Methods External root resorption was simulated on 88 extracted premolar teeth using tungsten bur in different depths (0.5 mm, 1 mm, and 2 mm). All teeth were scanned using a Cone beam CT (Carestream Dental, Atlanta, GA). Afterward, a training (70%), validation (10%), and test (20%) dataset were established. The performance of four DLMs including Random Forest (RF) + Visual Geometry Group 16 (VGG), RF + EfficienNetB4 (EFNET), Support Vector Machine (SVM) + VGG, and SVM + EFNET) and four hybrid models (DLM + FST: (i) FS + RF + VGG, (ii) FS + RF + EFNET, (iii) FS + SVM + VGG and (iv) FS + SVM + EFNET) was compared. Five performance parameters were assessed: classification accuracy, F1-score, precision, specificity, and error rate. FST algorithms (Boruta and Recursive Feature Selection) were combined with the DLMs to assess their performance. Results RF + VGG exhibited the highest performance in identifying ERR, followed by the other tested models. Similarly, FST combined with RF + VGG outperformed other models with classification accuracy, F1-score, precision, and specificity of 81.9%, weighted accuracy of 83%, and area under the curve (AUC) of 96%. Kruskal Wallis test revealed a significant difference (p = 0.008) in the prediction accuracy among the eight DLMs. Conclusion In general, all DLMs have similar performance on ERR identification. However, the performance can be improved by combining FST with DLMs.

Objective: The objective of this study was to evaluate external apical root resorption (EARR) in cases with extraction and non-extraction fixed orthodontic treatment. Methods: Ninety subjects were included in this study. The patients were divided into two groups: 43 with extraction treatment and 47 with non-extraction orthodontic treatment. EARR was measured using the crown-to-root ratio of the maxillary and mandibular incisors and canines on panoramic radiographs taken at the beginning (T0) and end of the treatment (T1). The Bonferroni corrected Z test was used for multiple comparisons. Results: There were 24 (55.8%) individuals in the extraction group and 12 (25.5%) in the non-extraction group, with a minimum of one tooth with severe resorption. There was no resorption in 0% of individuals in the extraction group and five (10.6%) individuals in the non-extraction group. There was a statistically significant correlation between the groups and the degree of resorption (p = 0.008). When the maxillary and mandibular teeth in the extraction group were compared, a significant difference was found in all degrees of resorption except for mild resorption. Conclusions: There was a significant difference in EARR between the extraction and non-extraction treatment groups, with maxillary incisors showing more resorption in the extraction treatment.

Objective: The aim of this study was to assess the knowledge, attitude, and clinical management orthodontically induced external root resorption (OIERR) among Lebanese orthodontists of varying years of experience. Methods: An online validated survey of 22 questions regarding OIERR was done among a randomly selected registered sample of 145 male and female Lebanese orthodontists. Results: Significant differences were found among orthodontists with different years of experience for: the factors leading to further investigation, the stage at which additional screening measures were taken, the periodic follow up assessment method, and the clinical management in case of generalized root loss of one-third or more than 4 mm, with p-values 0.035, 0.001, 0.007 and 0.024 respectively. Conclusions: Lebanese orthodontists had knowledge on potential risk factors, screening methods and period for OIERR. Those with more experience should depend on evidence based literature for clinical management of OIERR. [ABSTRACT FROM AUTHOR]

Introduction The following bibliographic review was carried out with the purpose of recognizing the clinical and radiographic characteristics that must be considered in the diagnosis of external root resorption, including treatments. Methods A bibliographic search was carried out in PubMed/Medline, Cochrane Library and Google Scholar databases under the term "external root resorption", from 2010 to 2022 in Spanish and English. Experimental studies and bibliographic reviews were selected, and finally 17 articles were included. Results The results obtained indicated that each type of resorption presents specific clinical characteristics that differentiate them, these are: for external inflammatory resorption a negative pulp vitality; for replacement external resorption the absence of mobility and metallic percussion; for cervical external resorption a pink coloration of the crown; superficial external resorption does not present any type of clinical symptoms and transient apical collapse presents a transient change in color. Conclusion External root resorptions require accurate and early diagnosis. A clinical examination should be performed with emphasis on the following: probing, coloration, mobility, and vitality tests.

Background/purpose: At present, there are no recognized guidelines or consensus for the treatment strategy of the asymptomatic tooth with external root resorption caused by an embedded tooth (et-ERR). Most clinicians would like prophylactic or concomitant root canal therapy (RCT) along with the extraction of the embedded tooth. The purpose of this study was to report the prognosis of external root resorption (ERR) and investigate the possibility to preserve the vital pulp of ERR tooth. Materials and methods: The patients who had asymptomatic et-ERR teeth were included. After extraction of the embedded tooth, the clinical process, prognosis, and adverse events were observed, including symptoms, clinical, and radiographic examination throughout the follow-up period. Results: A total of four cases with special features were reported. Over a follow-up period of up to 12 months, on clinical examination, 3 ERR teeth preserved pulp vitality without additional intervention except for tooth extraction and have kept normal function free from any symptoms. Radiographic examination showed bone regeneration and recovery of periodontal tissue. While one case failed to keep the vital pulp and ended in intentional replantation. Conclusion: As to et-ERR, if the embedded tooth can be promptly extracted with a minimally invasive technique and effective infection control, the pulp vitality of the et-ERR tooth is likely to be preserved. In this situation, the preferred management of asymptomatic et-ERR tooth is just followed up without prophylactic RCT.

Aim. This article presents an evaluation of different multidisciplinary treatment approaches to managing teeth with external and internal root resorptions. Methods. This study presents a clinical case of a 35-year-old female patient referred to Akdeniz University for dental issues. A comprehensive review of the literature was conducted, encompassing 21 articles sourced from PubMed and Web of Science over the past decade, including case reports and case series. Results. Case Report. A clinical case of a 35-year-old female patient seeking treatment for dental aesthetic concerns was reported and discussed. Intraoral examination revealed discoloration of maxillary anterior teeth and a sinus tract in the apical region of tooth #11. The resorption area was sealed with mineral trioxide aggregate. Afterward, the coronal part of the root was filled using the warm-vertical compaction method. During the final visit, non-vital bleaching was applied to teeth #11 and #21. After all these procedures, aesthetic coronal restorations were completed. Systematic Review. In the context of this clinical case, a literature review was conducted, encompassing an assessment of a total of 25 cases of external and internal resorptions. Among these cases, a combination of surgical and endodontic treatments was applied in 12 cases, while non-surgical endodontic treatment was performed in 13 cases. Conclusions. In the present case report, a patient who had both external and internal root resorptions was treated with mineral trioxide aggregate and flap operation, with no subsequent complications during the follow-up sessions. Among the 21 reports included in our review, 24 out of 25 treated teeth demonstrated successful outcomes, while only one tooth necessitated extraction.

The current literature on multiple idiopathic cervical root resorption (MICRR), a rare and aggressive form of external root resorption, is limited to case reports and series. Therefore, we performed a systematic review of this condition. A comprehensive search of PubMed, Embase, Web of science, Cochrane Library, CNKI, and WANFANG was conducted using key terms relevant to MICRR, supplemented by a grey literature search. Risk of bias was assessed using Cochrane's and Joanna Briggs Institute's tools. A total of 36 studies with 47 cases were included. MICRR is more common among younger females and may be related to hormonal changes and denosumab use. Initially, the premolars are usually affected but all permanent teeth may eventually be involved. Cone‐beam computed tomography is recommended for diagnosis and assessment of resorptive lesions. The management is focused on complete removal and restoration of the resorptive tissue to maintain the tooth's structural integrity. However, MICRR usually has a poor prognosis. Due to its invasive and aggressive behavior, MICRR requires greater attention. [ABSTRACT FROM AUTHOR]

Aim: This clinical study was undertaken to assess the effect of treatment with regenerative endodontic procedures (REPs) on 20 teeth with pulp necrosis, apical periodontitis, and external root resorption (ERR). Methodology: Teeth were treated with REPS utilizing the American Association of Endodontists (AAE) protocol. Quantitative assessment of changes in radiographic root area (RRA) were statistically analysed to assess changes in root dimensions after an average follow‐up period of 3 years. Results: All 20 teeth survived, 14 teeth (70%) were classified successful, and only 1 tooth (5%) failed throughout the study period. Based on the radiographic examination, all 20 teeth showed complete repair of the periapical lesions and arrested ERR. However, 5 teeth (25%) subsequently developed replacement resorption. The RRA between baseline and 3‐year follow‐up showed a significant difference for the total 20 teeth (p =.009). An analysis according to the trauma type and the extra‐oral time showed the RRA increase was significantly different in the non‐avulsion group (p =.015) and for the avulsion group with an extra‐oral time less than 60 min (p =.029). The RRA increase was not statistically significant in the avulsion group of extra‐oral time more than 60 min (p =.405). Nine teeth (45%) and 10 teeth (50%) responded to cold and electric pulp testing, respectively. Conclusions: Within the limitations of this study, the favourable outcomes of REPs were further confirmed for traumatized permanent necrotic teeth with ERR in terms of periapical lesion healed and a significant increase in RRA. The study contributes further evidence of the role of REPs in arresting ERR. [ABSTRACT FROM AUTHOR]

This Position Statement on root resorption represents the consensus of an expert committee convened by the European Society of Endodontology (ESE). The statement is based on current clinical and scientific evidence as well as the expertise of the committee. The aim is to provide clinicians with authoritative information on the aetiology, histopathology, clinical presentation and recommendations for the management of root resorption. It is the intention of the committee to update this position statement at appropriate intervals as further evidence emerges. [ABSTRACT FROM AUTHOR]

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Abstract Objective The purpose of this study was to evaluate pH and calcium ion release at the outer dentin surface of simulated external root resorption cavities after root canals obturated with bioceramic root canal sealer compared with those medicated with calcium hydroxide. Materials and Methods Sixty extracted human single‐rooted teeth were selected and instrumented. External root resorption cavities were prepared at the lingual surface of the root. The teeth were randomly divided into three groups: (1) Bioceramic sealer group, canals were obturated with gutta‐percha and BioRoot sealer; (2) Calcium hydroxide group, canals were medicated with UltraCal XS; (3) Control group, canals were left empty. Thirty specimens were used for evaluation of pH at 7, 14, and 28 days (n = 10 per group) and the other 30 specimens were used for evaluation of calcium ion diffusion at 28 days (n = 10 per group). Results Calcium hydroxide group showed the highest median pH value at all time points (7, 14, and 28 days). Both calcium hydroxide and bioceramic sealer groups showed significantly higher median pH values compared with control (p

The aims of this study were to use cone beam computed tomographic (CBCT) scans to assess the prevalence of second molar external root resorption (ERR) caused by impacted mandibular third molars and to associate the location and severity of ERR with the third molar position using 2 classification systems--1 proposed by Pell and Gregory and the other proposed by Winter. In this cross-sectional study, 2 calibrated observers evaluated a total of 107 CBCT scans (71 female and 36 male patients). After the presence or absence of ERR was determined, ERR was classified according to its location (cervical, middle, apical third, or root apex) and severity (mild, moderate, or severe resorption). The data were assessed with the Pearson chi-square test, the chi-square test for linear trend, and Poisson regression analysis. The significance level was set at P < 0.05. The prevalence of second molar ERR in the sample as a whole was 47.7% (n = 51). The prevalence was significantly higher (69.4%) for male patients (P = 0.002; Pearson chi-square test). The probability that ERR would affect the second molar was 1.71 times greater when the third molar exhibited the Pell and Gregory class IC position (95% Cl, 1.27-2.31) and 1.64 times greater when the third molar exhibited the Winter mesioangular position (95% Cl, 1.38-1.95). There was a statistically significant association between ERR location and severity; the cervical third was the most affected by mild ERR and the middle third was the most affected by severe ERR. The prevalence of mandibular second molar ERR caused by impacted third molars is high, especially in male patients. Mandibular third molars in the Pell and Gregory class IC position or Winter mesioangular position demonstrated greater potential to result in ERR of the adjacent second molar. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to retrospectively determine the prevalence of severe external root resorption in maxillary incisors during fixed orthodontic treatment and to evaluate the possible predisposing factors.Methods: The treatment records of 7000 patients who had been treated between 1990 and 2019 at the Department of Orthodontics Faculty of Dentistry Marmara University were examined, and a total of 120 patients with severe root resorption in at least one of their upper incisors were identified. The following data were retrieved from the patients' records and radiographs: gender, root morphology, overjet, overbite, treatment modality (extraction, non-extraction), treatment duration, buccal and palatal alveolar bone thickness for the maxillary incisors, and amount of movement of the incisal root apices and incisal edges. These data from a group of 90 patients with severe root resorption were compared with the data from a control group of 90 patients with minimal root resorption. The Chisquare test, the Mann–Whitney U-test, and the independent t-test were used for statistical analysis.Results:The prevalence of severe external root resorption was 3.23%, and the results demonstrated significant difference between the groups for the variables of treatment modality (extractions), treatment duration, thickness of the alveolar bone, and amount of incisor movement at the end of the treatment.Conclusion: It can be concluded that extractions, increased treatment duration, thin alveolar bone, and excessive incisor movement represent risk factors for severe root resorption in maxillary incisors following orthodontic treatment.

OBJECTIVES To find the frequency radiolucencies associated with the second molar adjacent to an impacted third molar in the maxilla as compared to the mandible. METHODOLOGY A cross-sectional descriptive study was conducted on 385 Orthopantomograms (OPG) of patients visiting Sharif Medical and Dental College (SMDC), Services Institute of Medical Sciences (SIMS) and Institute of Dentistry, CMH, Lahore Medical College, Lahore over a period of three months from December 2020 to February 2021. Patients above the age of 21 years were included in this study. Grossly carious third molars with inadequate tooth structure to be evaluated and patients with missing maxillary and mandibular third molars were excluded from the study. RESULTS The association between periapical radiolucencies (p=0.140), pericoronal radiolucencies (p=1.000) and external root resorption (p= 0.157) with the arch type (mandible/ maxilla) were not statistically significant but that of caries with the arch was significant (p≤0.001). CONCLUSION The periapical and pericoronal radiolucencies, caries and external root resorption associated with the second molar in the presence of an impacted third molar were higher in the mandible as compared to the maxilla.

Orthodontically induced external root resorption has been labeled an unavoidable consequence of orthodontic tooth movement (OTM). The objective of this study was to investigate the change in surface area (mm2) and volume (mm3) of endodontically treated teeth (ETT) compared with contralateral teeth with a vital pulp (VPT) after OTM. Seventy-six teeth were included in this retrospective analysis: ETT (n = 38) and VPT (n = 38). All teeth were evaluated using cone-beam computed tomographic imaging at 2 time periods: before OTM (T1) and after OTM (T2). Study teeth were segmented to include all areas contained within the lamina dura and then were converted into a mesh model for data calculation. The surface area (mm2) and volume (mm3) of each tooth were calculated at T1 and T2 based on the number of cubic voxels present within the mesh model. Statistical analysis was performed using a linear mixed-effects model. The average change in surface area after OTM in ETT was 13.01 mm2 and 19.95 mm2 in VPT (P <.05). The average percent change in surface area after OTM in ETT was 2.09% and 3.38% in VPT (P <.05). The average change in volume after OTM in ETT was 22.48 mm3 and 32.44 mm3 in VPT (P <.05). The average percent change in volume after OTM in ETT was 2.62% and 4.10% in VPT (P <.05). The results from this study suggest that ETT are less susceptible to root resorption after OTM than their vital counterparts. [ABSTRACT FROM AUTHOR]

Root resorption is the loss of dental hard tissue because of odontoclastic action. In permanent teeth, it is undesirable and pathological in nature. Root resorption may occur on the inner aspect of the root canal (internal root resorption) or on the outer aspect of the root (external root resorption). Regardless of its location, root resorption is irreversible, and may result in discomfort for the patient, requires management and/or, in some cases, results in the premature loss of the affected tooth. Root resorption is often challenging to accurately diagnose and manage. The aim of this narrative review is to present the relevant literature on the aetiology, pathogenesis, diagnosis and management, as well as discuss the future directions of diagnosis and management of root resorption. [ABSTRACT FROM AUTHOR]

Background and Objectives: Diffusion of hydroxide (OH) - and calcium (Ca) ++ ions through dentin may cease external root resorption. Calcium hydroxide (Ca(OH) 2 ), mineral trioxide aggregate (MTA), and calcium-enriched mixture (CEM) cement are the choices for this purpose due to their optimal properties. This study sought to analyze the effects of ultrasonic activation (UA) on pH and the release of calcium ions from Ca(OH) 2 , MTA, and CEM cement in external root resorption artificial defects. Materials and Methods: This in vitro research involved the instrumentation and shaping of the root canals of 150 single-rooted teeth (#F4). External defects were intentionally made on the middle one-third of the root surface. Teeth were randomly assigned to a negative control group ( n  = 10), one positive control group ( n  = 20), and six experimental groups (each n  = 20) according to the root canal filling material (Ca(OH) 2 paste, MTA, CEM, gutta-percha, Ca(OH) 2 paste+ultrasonic, MTA + ultrasonic, and CEM + ultrasonic). Ultrasonic energy was transferred to the test materials using a #25 spreader. Ca ++ concentration and pH were measured after 1, 7, 15, and 30 days in all groups. Statistical analysis involved the use of repeated measure analysis of variance (ANOVA) and paired-sample T -test ( P ≤ 0.05). Results: The levels of calcium ions and pH increased significantly over time in all groups ( P < 0.001). There were significant differences between the experimental groups in terms of pH and the concentration of released calcium ions at different times ( P < 0.001). The Ca(OH) 2 plus ultrasonic energy group ranked first, while the gutta-percha group ranked last in terms of release of calcium ions and pH. Conclusion: The Ca(OH) 2 , MTA, and CEM cement groups showed an increase in pH and the release of calcium ions at the external root resorption defects. Additionally, the application of ultrasonic energy increased the release of calcium ions at these sites., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2024 Azadeh Kheradyar et al.)

Objectives: The aim of this study is to investigate risk factors for external root resorption (ERR) of second molars (M2) associated with impacted third molars (M3), and to develop a prediction model that can offer dentists a reliable and efficient tool for predicting the likelihood of ERR., Methods: A total of 798 patients with 2156 impacted third molars were collected from three centres between 1 December 2018 and 15 December 2018. ERR was identified by cone beam computed tomography examinations. The effects of different risk factors on the presence/absence of ERR and its severity were analysed using Chi-square or Fisher test. Multivariate logistic regressive analysis with stepwise variable selection methods was performed to identify factors which were significant predictors for ERR and its severity. Subsequently, a prediction model was developed, and the model performance was validated internally and externally., Results: The overall incidence of ERR of second molars was 16.05%. The prediction model was established using six factors including position (upper/lower jaw), impact type, impact depth (PG: A-B-C), contact position, root number of M3, and age. In terms of internal validation, the prediction model demonstrated satisfactory performance, achieving an area under curve of 0.961 and a prediction accuracy of 0.907. As for external validation, the area under curve remained high at 0.953, with a prediction accuracy of 0.892., Conclusion: A risk prediction model for ERR was established in the present study. Position (upper or lower jaw), impact type, impact depth (PG: A-B-C), contact position, root number of M3, and age were identified as influencing variables which were significant predictors in the development of this predictive model. The prediction model showed great discrimination and calibration., Clinical Relevance: This prediction model has the potential to aid dentists and patients in making clinical decisions regarding the necessity of M3 extraction., Competing Interests: Conflict of interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Ping Ji reports financial support was provided by National Natural Science Foundation of China. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)

Background: Root resorption is a complex problem in endodontic treatment that considerably affects the structural integrity of teeth. This study aims to assess the biomechanical efficacy of various restorative materials and approaches in treating external root resorption, emphasizing their capacity to improve stress resistance and guarantee long-term success., Methods: This research employed finite element analysis (FEA) to assess stress distribution in mandibular premolars with external root resorption. Eight models, demonstrating apical and mid-level resorption, were repaired using mineral trioxide aggregate (MTA), Biodentine, or a mixture of these materials with gutta-percha. In order to evaluate each technique's biomechanical performance, the models were exposed to both vertical and oblique stresses., Results: The findings demonstrated that complete canal obturation with Biodentine or MTA greatly lowered stress levels, with Biodentine exhibiting a marginal advantage. The hybrid approach utilizing gutta-percha produced elevated stress concentrations, especially under oblique loading conditions., Conclusion: MTA and Biodentine are effective in enhancing resistance to biomechanical forces in teeth with external resorption. However, the combination of gutta-percha with these materials reduces resistance, especially under oblique forces. These findings highlight the importance of material selection in restoring resorbed teeth and improving clinical outcomes., Competing Interests: Human subjects: All authors have confirmed that this study did not involve human participants or tissue. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Celebi et al.)

This prospective study was designed to determine the prognosis of second molars with external root resorption (ERR-M2s) caused by embedded third molars (EM3s) following EM3 removal and explore related predictors. This study consecutively enrolled 58 participants who had asymptomatic second molars with apical external root resorption caused by EM3s. EM3s were extracted, and follow-up examinations were conducted at 1 week, 4 weeks, and 6 months. The primary outcome was prognosis of ERR-M2s after third molar extraction without any further intervention, as assessed via clinical and radiographic examinations. Potential predictors (sex, age, number of roots, EM3s position, type and degree of external root resorption) of prognosis were analyzed via univariable and multivariable analyses. A total of 63 ERR-M2s from 58 patients (16 males and 42 females; 19–57 years of age) were evaluated. At the last follow-up, 56 teeth (89%) remained asymptomatic and normal response to heat and cold tests. According to univariable analyses, ERR-M2s were more likely to remain normal response to heat and cold tests in younger patients. In the multivariable analysis, older age (odds ratio, 1.118; 95% confidence interval, 1.026–1.219; P <.05) and the type of all roots affected (odds ratio, 0.073; 95% confidence interval, 0.007–0.754; P <.05) were significantly associated with poor prognosis. Asymptomatic ERR-M2s have a high probability of remaining normal pulp without further intervention after EM3 extraction, especially in younger patients. No intervention except follow-up and observation is necessary. [ABSTRACT FROM AUTHOR]

Root resorption of the tooth may be a pathologic or physiologic phenomenon resulting in loss of root dentin and cementum. Broadly, it can be classified into two types - external and internal root resorption. Resorption that happens on the walls of the root canal is called internal resorption, and on the external surface of the root is called external resorption. It may be transient or progressive. The location of these resorptions can vary from the cervical to the apical region. This report presented a case of combined internal and external root resorption of a maxillary lateral incisor, a rare clinical phenomenon. [ABSTRACT FROM AUTHOR]

Background: Myelomeningocele (MMC) is a severe manifestation of spina bifida. Children with MMC have motor disability, hydrocephalus, skeletal abnormalities, and mental retardation. These individuals are more susceptible to caries due to poor oral hygiene, carbohydrate‐rich diet, prolonged use of sugar‐containing medications and limited motor abilities. Latex allergy is an important factor to be considered during the dental rehabilitation of such patients. Case Report: A 3‐year‐old girl visited the dental clinic with the chief complaint of multiple carious teeth and H/o neural tube defect (NTD) which had been operated on at the age of 6 weeks. On dental examination, multiple dental abscesses and severe early childhood caries were noted. Radiographic evaluation revealed internal root resorption of tooth "K" and external root resorption of tooth "T." The two teeth were treated with ledermix paste followed by obturation with Vitapex® (Diadent Group International Inc., Burnaby, BC, Canada) along with triple antibiotic paste and placement of stainless steel crown (SSC). A latex‐free environment was maintained during the entire treatment to prevent allergic reaction. A follow up after 42 months indicated clinical and radiographical success. Conclusion: The paper reports succesfull management of internal and external root resorption as well as latex allergy in a dental operatory. The dental perspective while dealing with patients having NTD is limited. Explaining the particulars of the treatment plan will aid in management of such cases. [ABSTRACT FROM AUTHOR]

Introduction: Micro-osteoperforation (MOP) and Low Level Laser Therapy (LLLT) are rapidly gaining popularity in clinical practice due their proven success in accelerating tooth movement and acceptable patient compliance. However, literature shows an inconsistent and variable evidence of their iatrogenic effects on the root and pulp due to biological variations of the samples chosen by the previously studies. Aim: To evaluate and compare the rate of tooth movement, changes in amount of external root resorption and pulp vitality in teeth during en masse anterior retraction associated with MOP and LLLT using split mouth technique. Materials and Methods: This was a double blinded, single center split mouth randomised clinical trial conducted at Faculty of Dental Sciences, MS Ramaiah University of Applied Sciences, Bangalore, Karnataka, India from March 2019 to October 2019. Total of 11 patients with bimaxillary dentoalveolar protrusion which required all four first premolar extractions were included in the study. Nickel Titanium (NiTi) closed coil springs were used for en masse retraction in upper and lower arches with force of 150g per side. Root resorption of all anterior teeth was evaluated using Cone Beam Computed Tomography systems (CBCT) and pulp vitality was checked using cold test after 4 months. The data was entered in Microsoft excel and the Statistical Package for Social Sciences software (SPSS) version 18.5 (SPSS Inc, Chicago) software was used for data entry and statistical analysis. A p-value of less than 0.05 was considered as statistically significant. Results: Total of 11 patients in which 9 were females and 2 males aged between 18-30 years with mean age 19±4.21 year, participated in this trial. LLLT (4 mm) and MOP (4.05 mm) showed similar performance in acceleration of tooth compared to each other. The overall root resorption was more in the experimental groups (LLLT- 2.60 mm, MOP- 2.84 mm) compared to the allotted controls. However, the canine showed less root resorption in both the experimental groups compared to the control. The overall root resorption was similar in both the experimental groups. The canine in LLLT group (0.30 mm) showed less root resorption compared to canine in MOP group (0.59 mm). There was no change in the pulp vitality status in both the experimental groups and the control groups. Conclusion: The overall root resorption in a given quadrant increases with increased rate of tooth movement. The tooth which was subjected to acceleratory orthodontic technique showed less root resorption compared to control. The tooth subjected to LLLT showed less root resorption as compared to the tooth subjected to MOP. [ABSTRACT FROM AUTHOR]

Objective: The purpose of this study was to evaluate pH and calcium ion release at the outer dentin surface of simulated external root resorption cavities after root canals obturated with bioceramic root canal sealer compared with those medicated with calcium hydroxide. Materials and Methods: Sixty extracted human single‐rooted teeth were selected and instrumented. External root resorption cavities were prepared at the lingual surface of the root. The teeth were randomly divided into three groups: (1) Bioceramic sealer group, canals were obturated with gutta‐percha and BioRoot sealer; (2) Calcium hydroxide group, canals were medicated with UltraCal XS; (3) Control group, canals were left empty. Thirty specimens were used for evaluation of pH at 7, 14, and 28 days (n = 10 per group) and the other 30 specimens were used for evaluation of calcium ion diffusion at 28 days (n = 10 per group). Results: Calcium hydroxide group showed the highest median pH value at all time points (7, 14, and 28 days). Both calcium hydroxide and bioceramic sealer groups showed significantly higher median pH values compared with control (p <.001). Comparing within groups, both bioceramic sealer group and calcium hydroxide group showed significantly decreased median pH over time, while the median pH of the control did not show any significant difference among Days 7, 14, and 28. Both calcium hydroxide and bioceramic sealer groups had significantly higher calcium ion release than control. Notably, bioceramic sealer group showed significantly higher calcium ion release than the calcium hydroxide group (p <.01). Conclusions: Root canals obturated with gutta‐percha and bioceramic sealer showed high calcium ion levels at the simulated external root resorption cavities but did not show an extended period of alkaline pH. [ABSTRACT FROM AUTHOR]

Introduction: Micro-osteoperforation (MOP) and Low Level Laser Therapy (LLLT) are rapidly gaining popularity in clinical practice due to their proven success in accelerating tooth movement and acceptable patient compliance. However, literature shows an inconsistent and variable evidence of their iatrogenic effects on the root and pulp due to biological variations of the samples chosen by the previous studies. Aim: To evaluate and compare the rate of tooth movement, changes in amount of external root resorption and pulp vitality in teeth during en masse anterior retraction associated with MOP and LLLT using split mouth technique. Materials and Methods: This was a double blinded, single centre split mouth randomised clinical trial conducted at Faculty of Dental Sciences, MS Ramaiah University of Applied Sciences, Bangalore, Karnataka, India from March 2019 to October 2019. Total of 11 patients with bimaxillary dentoalveolar protrusion which required all four first premolar extractions were included in the study. Nickel Titanium (NiTi) closed coil springs were used for en masse retraction in upper and lower arches with force of 150 g per side. Root resorption of all anterior teeth was evaluated using Cone Beam Computed Tomography systems (CBCT) and pulp vitality was checked using cold test after four months. The data was entered in Microsoft excel and the Statistical Package for Social Sciences software (SPSS) version 18.5 (SPSS Inc, Chicago) software was used for data entry and statistical analysis. A p-value of less than 0.05 was considered as statistically significant. Results: Total of 11 patients in which 9 were females and 2 males aged between 18-30 years with mean age 19±4.21 year, participated in this trial. LLLT (4 mm) and MOP (4.05 mm) showed similar performance in acceleration of tooth compared to each other. The overall root resorption was more in the experimental groups (LLLT- 2.60 mm, MOP- 2.84 mm) compared to the allotted controls. However, the canine showed less root resorption in both the experimental groups compared to the control. The overall root resorption was similar in both the experimental groups. The canine in LLLT group (0.30 mm) showed less root resorption compared to canine in MOP group (0.59 mm). There was no change in the pulp vitality status in both the experimental groups and the control groups. Conclusion: The overall root resorption in a given quadrant increases with increased rate of tooth movement. The tooth which was subjected to acceleratory orthodontic technique showed less root resorption compared to control. The tooth subjected to LLLT showed less root resorption as compared to the tooth subjected to MOP.

Objective: The aim of this study was to retrospectively determine the prevalence of severe external root resorption in maxillary incisors during fixed orthodontic treatment and to evaluate the possible predisposing factors. Methods: The treatment records of 7000 patients who had been treated between 1990 and 2019 at the Department of Orthodontics Faculty of Dentistry Marmara University were examined, and a total of 120 patients with severe root resorption in at least one of their upper incisors were identified. The following data were retrieved from the patients' records and radiographs: gender, root morphology, overjet, overbite, treatment modality (extraction, non-extraction), treatment duration, buccal and palatal alveolar bone thickness for the maxillary incisors, and amount of movement of the incisal root apices and incisal edges. These data from a group of 90 patients with severe root resorption were compared with the data from a control group of 90 patients with minimal root resorption. The Chisquare test, the Mann-Whitney U-test, and the independent t-test were used for statistical analysis. Results: The prevalence of severe external root resorption was 3.23%, and the results demonstrated significant difference between the groups for the variables of treatment modality (extractions), treatment duration, thickness of the alveolar bone, and amount of incisor movement at the end of the treatment. Conclusion: It can be concluded that extractions, increased treatment duration, thin alveolar bone, and excessive incisor movement represent risk factors for severe root resorption in maxillary incisors following orthodontic treatment. [ABSTRACT FROM AUTHOR]

Background: Pneumatized articular eminence (PAT) and roof of the glenoid fossa (PRGF) are recognized when accessory air cells are found within the zygomatic process of the temporal bone. Pneumatization in this region facilitates the spread of tumors and fractures. During Zygomatic implant placement and TMJ surgical procedures, namely eminectomy and miniplate insertions, various complications might arise due to pneumatized PAT and PRGF. Cone-beam computed tomography (CBCT) provides reliable and accurate information to determine the characteristics, the extent of pneumatization, and its relationship to the adjacent structures. So, recognizing the variations of PAT and PRGF in different populations is of clinical importance. Objective: The purpose of this study was to assess the prevalence of pneumatization of articular tubercle (PAT) and pneumatization of PRGF in the North- East Indian population by using CBCT. Materials and Methods: The study was carried out among 500 patients. The prevalence and significance of differences among the variables were carried out by analysis of variance (ANOVA) and Chi-square test. Data were analyzed by using Statistical Package for the Social Sciences (SPSS) software program, version 21 (IBM). Results: The mean age with pneumatization was 45.27 ± 18.00 years. The prevalence of PAT and PRGF was found to be 24.6% and 24.4%, respectively. Bilateral PAT was detected in (6%) patients. The occurrence of unilateral PAT cases was found to be more than bilateral PAT cases (

A male patient aged 28 years presented with a chief complaint of discolored left central incisor and missing tooth, due to road traffic accident 15 years ago with no associated symptoms. Clinical and radiographic examination revealed no pulp to response to vitality test, large periapical radiolucency, and root resorption of the middle third of the root. A definite diagnosis of pulpal necrosis with asymptomatic apical periodontitis and external resorption was made. Root canal treatment was done, and the extent of the lesion was analyzed and planned for surgical management. The periapical lesion was curetted, and the external resorption site was sealed with a matrix of Biodentine and platelet-rich fibrin. The case has shown successful healing after 3-year follow-up.

Multiple root resorption with a huge periapical lesion is considered as a great challenge in daily endodontic practice. The anterior teeth are easy victim to traumatic injuries, and thereby a common site for huge lesions of the jaw. Considering hard tissue loss in surgical intervention, the non-surgical modality with triple antibiotic paste (TAP) and Mineral Trioxide Aggregate (MTA) as an obturation material is gaining popularity in managing such lesions. The present case shows successful healing outcome of a large periapical lesion with inflammatory root resorption in mandibular anterior teeth with non-surgical endodontic modalities. [ABSTRACT FROM AUTHOR]

Abstract Successful non‐surgical orthograde retreatment of a tooth with external root resorption in apical third of root and overfilling material beyond the apical barrier which was diagnosed with the help of cone beam computed tomography (CBCT), was reported. Biodentine was used as the treatment of choice for obturation of resorption area.

ABSTRACT Objective: The present study aimed at comparing the external lateral root resorption (ELRR) and external apical root resorption (EARR) between teeth moved through the atrophic edentulous ridge and those undergoing the usual orthodontic movement. Methods: Fifty-four premolars were evaluated, where 27 of them had been moved toward the edentulous ridge (Group 1) and 27 from the same patient, had not been translated, which comprised the control group (Group 2). ELRR was evaluated by 0-3 scores and EARR was evaluated by 0-4 scores, before and after movement. Measurements were compared by Kruskal-Wallis and Student-Newman-Keuls tests. Results: ELRR increased statistically only in the Group 1 (p< 0.05). After orthodontic treatment, it was observed that almost 56% (n = 15) of teeth in Group 1 presented scores 2 and 3, while Group 2 presented scores 2 and 3 in about 11% (n= 3) of the teeth. EARR increased in both groups after orthodontic movement, however, statistically analyses showed no significant differences between groups (p> 0.05). Conclusions: Orthodontic movement into the atrophic edentulous ridge is subject to a greater lateral external root resorption.

Osteoblastoma is a rare, benign bone tumor primarily affecting the spine but can occasionally involve the jaws, particularly the mandible. This report discusses the case of a 38-year-old female patient presenting with mild pain and swelling in the left mandibular region for the past few months. Clinical, radiographic, and histopathological evaluation confirmed the diagnosis of osteoblastoma. A conservative surgical excision was performed. No recurrence was observed on follow-up. Differential diagnoses included low-grade osteosarcoma, osteoid osteoma, and other bone-forming lesions. This case report emphasizes the importance of distinguishing osteoblastoma from similar lesions to ensure appropriate treatment and favorable prognosis., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Aarthi et al.)

Idiopathic root resorption is characterized by the gradual destruction of tooth roots without a clear cause; the possible underlying factors include genetic predispositions, immune system abnormalities, or environmental influences. This case report highlights an unusual instance of a 27-year-old young female patient who presented with multiple decayed teeth; the orthopantomographic examination incidentally revealed extensive root resorptions. Thorough biochemical investigations such as acid phosphatase, alkaline phosphatase, thyroid-stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3), as well as calcium, were within normal limits, with no identifiable local or systemic factors, leading to a diagnosis of idiopathic root resorption. Diagnosing multiple idiopathic external apical root resorption (MIEARR) is particularly challenging, underscoring the importance of regular monitoring and comprehensive dental care to prevent further deterioration. The uniqueness of our case report lies in its investigative approach, employing advanced diagnostic techniques such as nano CT and scanning electron microscopy (SEM). It also includes a comparative analysis of cases previously reported in the literature., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Human Ethical Committee, Saveetha Dental College and Hospitals issued approval IHEC/SDC/OMED-2104/23/117. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Murugappan et al.)

This comprehensive meta-analysis investigated the effects of Rapid Maxillary Expansion (RME) on external root resorption, which is a prevalent orthodontic treatment intended to correct transverse maxillary deficiency and constricted dental arches. By conducting a systematic literature search across prominent electronic databases, including the Cochrane Library, EMBASE, LILACS, MEDLINE, PubMed, and Web of Science, the study compiled evidence until April 2023. A spectrum of search terms was utilized to capture diverse aspects of root resorption, RME, palatal expansion methods, and tooth erosion. Registered with INPLASY (202430057), the meta-analysis meticulously screened 11 studies that fulfilled stringent inclusion criteria. The quality of these studies was assessed using the Cochrane Bias Risk Assessment Tool for Randomized Controlled Trials (RCTs) and the Methodological Index for Non-Randomized Studies (MINORS) for other research designs. The collective analyses disclosed a substantial impact of RME on external root resorption, indicating that the treatment may induce pronounced root erosion. Subgroup analyses further elucidated distinct patterns in root resorption among various types of RME, underscoring the variability in treatment outcomes and the need for personalized care. Consequently, the meta-analysis unequivocally confirmed that external root resorption may be a concerning consequence of RME treatment, necessitating thorough monitoring and management strategies to mitigate potential adverse effects on dental health., Competing Interests: None., (AJTR Copyright © 2024.)

Objectives: This study investigated the association of changes in cementum protein-1 (CEMP-1), dentine phosphoprotein (DPP), and c-terminal cross-linked telopeptide of type I collagen (CTX-I) levels in human gingival crevicular fluid (GCF) under constant load with external root resorption volume and amount of tooth movement. Materials and methods: In total, 11 healthy adult patients (mean age, 23.5 years [range, 18.3–37.7]; four men and seven women) were enrolled. GCF samples were obtained from premolars at T0, T1 (1 day), T2 (1 week), T3 (2 weeks), T4 (4 weeks), and T5 (8 weeks) under constant 100-gm buccal tipping force. Opposite premolars were used as controls. Teeth were extracted at T5, followed by quantification of external root resorption volume and histological analysis. Results: In the test group, T5/T0 ratios of CEMP-1 and DPP levels, differential CEMP-1 levels between T5 and T0, and differential DPP levels between T2 and T0 correlated positively with root resorption volume (r = 0.734, 0.730, 0.627, and 0.612, respectively, all p < 0.05). CEMP-1 levels at T0 and T3 correlated negatively with root resorption volume (r = −0.603 and −0.706; all p < 0.05). CTX-I levels at T5 correlated positively with the amount of tooth movement (r = 0.848, p < 0.01). Conclusions: Alterations in CEMP-1 and DPP levels in human GCF at specific timepoints during orthodontic treatment may be associated with different degrees of external root resorption. Clinical relevance: This study demonstrates that changes in the levels of tissue-specific biomarkers in GCF may facilitate early detection of external root resorption during orthodontic tooth movement. [ABSTRACT FROM AUTHOR]

Aim: To evaluate the frequency of external root resorption on adjacent teeth of common cysts and ameloblastomas of the jaw in an Asian population and to investigate the association of size or location of the lesions on such root resorption potential. Material and methods: A retrospective radiographic study using cone beam computed tomography (CBCT) scans to examine the frequency of external root resorption (ERR) of teeth in proximity of 160 lesions comprising periapical radicular cysts, dentigerous cysts, odontogenic keratocysts and ameloblastomas was carried out. Fisher's exact test, Pearson's chi square test and logistic regression analysis were used to investigate differences in the frequency of ERR of teeth adjacent to these lesions and to assess the association of the size or location of the lesions on such root resorption potential. Results and conclusions: There were 40% of lesions located in the maxilla and 60% in the mandible. Adjacent teeth ERR was noted in 61 (38.1%) lesions. Compared with odontogenic keratocysts, ameloblastomas were eight times more likely (p = 0.005) and dentigerous cysts were three times more likely (p = 0.028) to be associated with ERR after adjusting for the size and location of the lesion. Location and size of a lesion did not influence the prevalence of adjacent teeth ERR. The four types of lesions studied exhibit different frequencies of ERR in adjacent teeth. Based on this study, the presence of ERR in adjacent teeth is a useful supportive measure in the diagnosis of these lesions. [ABSTRACT FROM AUTHOR]