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Purpose: To investigate how cycling time-trial (TT) performance changes over a cycling season, both in a "fresh" state and in a "fatigued" state (durability). Additionally, the aim was to explore whether these changes are related to changes in underlying physiological factors such as gross efficiency, energy expenditure (EE), and substrate oxidation (fat oxidation [FatOx] and carbohydrate oxidation [CarbOx]). Methods: Sixteen male semiprofessional cyclists visited the laboratory on 3 occasions during a cycling season (PRE, START, and IN) and underwent a performance test in both fresh and fatigued states (after 38.1 [4.9] kJ/kg), containing a submaximal warm-up for the measurement of gross efficiency, EE, FatOx, and CarbOx and a maximal TT of 1 (TT1min) and 10 minutes (TT10min). Results were compared across states (fresh vs fatigued) and periods (PRE, START, and IN). Results: The average power output (PO) in TT1min decreased (P <.05) from fresh to fatigued state across all observed periods, whereas there was no change in the PO in TT10min. Over the course of the season, the PO in TT1min in the fatigued state improved more compared with the PO in TT1min in the fresh state. Furthermore, while EE did not significantly change, there was an increase in FatOx and a decrease in CarbOx toward the fatigued state. These changes diminished during the cycling season (IN), indicating a greater contribution of CarbOx in the fatigued state. Conclusions: TT1min performance is more sensitive to fatigue compared with TT10min. Also, during a cycling season, durability improves more when compared with fresh maximal POs, which is also observed in the changes in substrate oxidation. [ABSTRACT FROM AUTHOR]

Purpose: One hundred years ago, Hill and Lupton introduced the concept of maximal oxygen uptake ( V ˙ O 2 max), which is regarded as "the principal progenitor of sports physiology." We provide a succinct overview of the evolvement of research on V ˙ O 2 max , from Hill and Lupton's initial findings to current debates on limiting factors for V ˙ O 2 max and the associated role of convective and diffusive components. Furthermore, we update the current use of V ˙ O 2 max in elite endurance sport and clinical settings. Practical Applications and Conclusions: V ˙ O 2 max is a healthy and active centenarian that remains a very important measure in elite endurance sports and additionally contributes as an important vital sign of cardiovascular function and fitness in clinical settings. Over the past 100 years, guidelines for the test protocols and exhaustion criteria, as well as the understanding of limiting factors for V ˙ O 2 max , have improved dramatically. Presently, possibilities of accurate and noninvasive determination of the convective versus diffusive components of V ˙ O 2 max by wearable sensors represent an important future application. V ˙ O 2 max is not only an indicator of cardiorespiratory function, fitness, and endurance performance but also represents an important biomarker of cardiovascular function and health to be included in routine assessment in clinical practice. [ABSTRACT FROM AUTHOR]

Background: Elite sport is continuously evolving. World records keep falling and athletes from a longer list of countries are involved. Purpose: This commentary was designed to provide insights into present and future trends associated with world-class endurance training based on the perspectives, experience, and knowledge of an expert panel of 25 applied sport scientists. Results: The key drivers of development observed in the past 10–15 years were related to (1) more accessible scientific knowledge for coaches and athletes combined with (2) better integration of practical and scientific exchange across multidisciplinary perspectives within professionalized elite athlete support structures, as well as (3) utilization of new technological advances. Based on these perspectives, we discerned and exemplified the main trends in the practice of endurance sports into the following categories: better understanding of sport-specific demands; improved competition execution; larger, more specific, and more precise training loads; improved training quality; and a more professional and healthier lifestyle. The main areas expected to drive future improvements were associated with more extensive use of advanced technology for monitoring and prescribing training and recovery, more precise use of environmental and nutritional interventions, better understanding of athlete–equipment interactions, and greater emphasis on preventing injuries and illnesses. Conclusions: These expert insights can serve as a platform and inspiration to develop new hypotheses and ideas, encourage future collaboration between researchers and sport practitioners, and, perhaps most important, stimulate curiosity and further collaborative studies about the training, physiology, and performance of endurance athletes. [ABSTRACT FROM AUTHOR]

Purpose: The primary objective was to assess the performance benefits of caffeine (CAF) supplementation in habitual users. Importantly, this investigation was designed to account for the potential confounding effects of CAF withdrawal (CAFW), which are inherent and common in previous work. Methods: Ten CAF-consuming (394 [146] mg·d−1) recreational cyclists (age 39.1 [14.9] y; maximum oxygen consumption 54.2 [6.2] mL·kg–1·min–1) completed four 10-km time trials (TTs) on a cycle ergometer. On each trial day, 8 hours before reporting to the laboratory, subjects consumed 1.5 mg·kg–1 CAF to prevent withdrawal (no withdrawal [N]) or a placebo (PLA; withdrawal [W]). Then, 1 hour prior to exercise, they received either 6 mg·kg–1 CAF or PLA. These protocols were repeated 4 times, employing all combinations of N/W and CAF/PLA. Results: CAFW did not impair TT power output (PLAW vs PLANP =.13). However, preexercise CAF only improved TT performance when compared to PLA in the W condition (CAFN vs PLAWP =.008, CAFW vs PLAWP =.04), not when W was mitigated (PLAN vs CAFNP =.33). Conclusions: These data indicate that preexercise CAF only improves recreational cycling performance when compared to bouts preceded by CAF abstinence, suggesting that habitual users may not benefit from 6 mg·kg–1 of CAF and that previous work may have overstated the value of CAF supplementation for habitual users. Future work should examine higher doses of CAF for habitual users. [ABSTRACT FROM AUTHOR]

Thermoregulation is impaired in individuals with a spinal cord lesion (SCI), affecting sweat capacity, heat loss, and core temperature. This can be particularly problematic for athletes with SCI who exercise in hot and humid conditions, like those during the Tokyo 2020 Paralympic Games. Heat acclimation can support optimal preparation for exercise in such challenging environments, but evidence is limited in endurance athletes with SCI. We evaluated whether seven consecutive days of exercise in the heat would result in heat acclimation. Five elite para-cycling athletes with SCI participated (two females, three males, median (Q1-Q3) 35 (31–51) years, four with paraplegia and one with tetraplegia). All tests and training sessions were performed in a heat chamber (30°C and 75% relative humidity). A time-to-exhaustion test was performed on day 1 (pretest) and day 7 (posttest). On days 2–6, athletes trained daily for one hour at 50–60% of individual peak power (PPeak). Comparing pretest and posttest, all athletes increased their body mass loss (p=0.04), sweat rate (p=0.04), and time to exhaustion (p=0.04). Effects varied between athletes for core temperature and heart rate. All athletes appeared to benefit from our heat acclimation protocol, helping to optimize their preparation for the Tokyo 2020 Paralympic Games. [ABSTRACT FROM AUTHOR]

Purpose: Bothmaximal-intensity exercise and altitude exposure challenge the pulmonary system that may reach itsmaximal capacities. Expiratory flow limitation (EFL) and exercise-induced hypoxemia (EIH) are common in endurance-trained athletes. Furthermore, because of their smaller airways and lung size, women, independently of their fitness level, may be more prone to pulmonary limitations duringmaximalintensity exercise, particularly when performed in hypoxic conditions. The objective of this study was to investigate the impact of sex and fitness level on pulmonary limitations during maximal exercise in normoxia and their consequences in acute hypoxia. Methods: Fifty-one participants were distributed across four different groups according to sex and fitness level. Participants visited the laboratory on three occasions to perform maximal incremental cycling tests in normoxia and hypoxia (inspired oxygen fraction = 0.14) and two hypoxic chemosensitivity tests. Pulmonary function and ventilatory capacities were evaluated at each visit. Results: EIH was more prevalent (62.5% vs 22.2%, P = 0.004) and EFL less common (37.5% vs 70.4%, P = 0.019) in women than men. EIH prevalence was different (P = 0.004) between groups of trained men (41.7%), control men (6.7%), trained women (50.0%), and control women (75.0%). All EIH men but only 40% of EIH women exhibited EFL. EFL individuals had higher slope ratio (P = 0.029), higher ventilation (VE) (P < 0.001), larger ΔVO2max (P = 0.019), and lower hypoxia-relatedV E increase (P < 0.001). Conclusions: Women reported a higher EIH prevalence than men, regardless of their fitness level, despite a lower EFL prevalence. EFL seems mainly due to the imbalance between ventilatory demands and capacities. It restricts ventilation, leading to a larger performance impairment during maximal exercise in hypoxic conditions. [ABSTRACT FROM AUTHOR]

Purpose: Caffeine is a commonly used ergogenic aid for endurance events; however, its efficacy and safety have been questioned in hot environmental conditions. The aim of this study was to investigate the effects of acute caffeine supplementation on cycling time to exhaustion and thermoregulation in the heat. Methods: In a double-blind, randomised, cross-over trial, 12 healthy caffeine-habituated and unacclimatised males cycled to exhaustion in the heat (35 °C, 40% RH) at an intensity associated with the thermoneutral gas exchange threshold, on two separate occasions, 60 min after ingesting caffeine (5 mg/kg) or placebo (5 mg/kg). Results: There was no effect of caffeine supplementation on cycling time to exhaustion (TTE) (caffeine; 28.5 ± 8.3 min vs. placebo; 29.9 ± 8.8 min, P = 0.251). Caffeine increased pulmonary oxygen uptake by 7.4% (P = 0.003), heat production by 7.9% (P = 0.004), whole-body sweat rate (WBSR) by 21% (P = 0.008), evaporative heat transfer by 16.5% (P = 0.006) and decreased estimated skin blood flow by 14.1% (P < 0.001) compared to placebo. Core temperature was higher by 0.6% (P = 0.013) but thermal comfort decreased by − 18.3% (P = 0.040), in the caffeine condition, with no changes in rate of perceived exertion (P > 0.05). Conclusion: The greater heat production and storage, as indicated by a sustained increase in core temperature, corroborate previous research showing a thermogenic effect of caffeine ingestion. When exercising at the pre-determined gas exchange threshold in the heat, 5 mg/kg of caffeine did not provide a performance benefit and increased the thermal strain of participants. [ABSTRACT FROM AUTHOR]

This review investigates the effect of two different concurrent training sequences on endurance performance. The sequences investigated are Endurance–Resistance (ER) and Resistance–Endurance (RE). A literature search is conducted of the SPORTDiscus and Medline databases. The included studies are randomized control trials, which compare the effect of ER and RE on at least one endurance performance variable. A PEDro scale is used to assess the methodological quality of the articles in this review. Of a total of 152 articles identified during the initial screening, 15 studies meet the inclusion criteria. These studies include 426 participants (298 males and 128 females), with 212 of the participants training with ER and 214 with RE. The results are presented as the percentage change of the mean from pre- to post-test. All the studies show an improvement in endurance from pre to post for both interventions, except for the RE group in one study. This review finds small and non-conclusive sequence effects between ER and RE, suggesting that the sequence of concurrent training is not of great importance in relation to endurance performance. [ABSTRACT FROM AUTHOR]

The current study examined whether meditation experience is associated with changes in endurance performance and inhibitory control-relevant neurocognitive functions caused by mental fatigue. Twenty-four athletes with meditation experience (AME) and twenty-five athletes without meditation experience (AWME) underwent a 30-min incongruent Stroop test in mental fatigue condition (MF) and a 30-min congruent Stroop test in control condition (CON) in a randomised-counterbalanced order. Inhibitory control-relevant neurocognitive functions were assessed using Flanker task and event-related potentials, followed by an endurance task using the Bruce treadmill protocol. Visual analogue scale was used to evaluate perceived mental fatigue (VAS-MF) before (T1), after Stroop test (T2) and after Flanker task (T3), and VAS for motivation (VAS-M) was used to evaluate motivation in Flanker task and endurance task. Results indicated that, compared to the CON, AWME in the MF exhibited overall lower accuracy, smaller incongruent N2 amplitude of the Flanker task (ps <.05), and shorter time to exhaustion (TTE) of the endurance task (p <.001), whereas AME did not exhibited difference in these outcomes between the conditions. Along with athletes in the MF reported lower VAS-M in endurance task. These findings suggest the benefits of meditation experience in mitigating the negative effects of mental fatigue. [ABSTRACT FROM AUTHOR]

Introduction Methods Results Conclusion The phenotypic consequences of the p.Arg577Ter variant in the α‐actinin‐3 (ACTN3) gene are suggestive of a trade‐off between performance traits for speed and endurance sports. Although there is a consistent association of the c.1729C allele (aka R allele) with strength/power traits, there is still a debate on whether the null allele (c.1729T allele; aka X allele) influences endurance performance. The present study aimed to test the association of the ACTN3 p.Arg577Ter variant with long‐distance endurance athlete status, using previously published data with the Brazilian population.Genotypic data from 203 long‐distance athletes and 1724 controls were analysed in a case–control approach.The frequency of the X allele was significantly higher in long‐distance athletes than in the control group (51.5% vs. 41.4%; p = 0.000095). The R/X and X/X genotypes were overrepresented in the athlete group. Individuals with the R/X genotype instead of the R/R genotype had a 1.6 increase in the odds of being a long‐distance athlete (p = 0.012), whereas individuals with the X/X genotype instead of the R/R genotype had a 2.2 increase in the odds of being a long‐distance athlete (p = 0.00017).The X allele, mainly the X/X genotype, was associated with long‐distance athlete status in Brazilians. [ABSTRACT FROM AUTHOR]

The presence of oxygen in active muscles dictates substrate metabolism which is crucial for sport performance. However, it's information in dragon boat races is limited. This study aimed to evaluate muscle oxygenation and energy substrate utilization during 200-m and 500-m dragon boat races among elite athletes. Ten male dragon boat athletes participating in international competitions (age 26.60 ± 3.20 years, weight 79.54 ± 3.36 kg, height 174.80 ± 5.67 cm) completed 200-m and 500-m simulated race trials on an ergometer in a randomized, counterbalance, crossover fashion, with a 2-day separation. Near-infrared spectroscopy (NIRS) monitors were placed on the biceps brachii (BB) and latissimus dorsi (LD) to investigate tissue saturation index (TSI), oxyhemoglobin concentration (O2Hb), deoxyhemoglobin concentration (HHb), and total hemoglobin (tHB) during the trials, and gas analyzer was employed to evaluate energy substrate utilization. The results revealed that during 200-m and 500-m races, TSI, O2Hb, and tHb in the BB significantly decreased (P<0.05), whereas HHb significantly increased (P<0.05). In the LD, this change was observed only in 200-m race (P<0.05). When comparing between the distances, all oxygen parameters in the BB were significantly higher in 500-m than 200-m (P<0.05), while in the LD, TSI, O2HB, and tHb were significantly higher (P<0.05). Total energy and energy from carbohydrate were also significantly higher in 500-m than 200-m race (P<0.01). The results of this study indicate that there is difference in muscle oxygenation and energy substrate expenditure during 200-m and 500-m dragon boat races. This disparity may be resulted from different muscle recruitment patterns, as indicated by difference in oxygen parameters in the BB and LD during the races. This study provides new knowledge to the area of paddle sports and offers practical insights that can help coaches and related persons to optimize athletic performance during training and competitions. More researches are required to clarify the mechanisms underlying the differences in muscle oxygenation in different dragon boat race distances. [ABSTRACT FROM AUTHOR]

Ischemic preconditioning (IPC), which involves episodes of blood flow restriction followed by reperfusion, has uncertain effects on athletes. Additionally, employing sports-specific tests that are highly familiar to athletes can enhance methodological rigor in determining IPC's effects on taekwondo performance. This study aimed to investigate IPC's influence on taekwondo athletes' performance through two studies. To induce occlusion in both studies, the cuff was inflated to an individualized occlusion pressure established for each athlete's lower limb, with four cycles of occlusion lasting five minutes each, alternated with five-minute reperfusion intervals. Both traditional frequentist statistics and Bayesian analysis were employed. In the first study, eleven high-level athletes were subjected to either IPC or a placebo (SHAM) procedure on both legs, followed by performing countermovement jumps (CMJs) and a specific taekwondo endurance test. However, no significant differences were observed in taekwondo endurance performance or CMJ between the IPC and SHAM conditions. The second study involved fourteen elite athletes who underwent the same IPC or SHAM conditions, performing CMJ and three bouts of the Multiple Frequency Speed of Kick test (FSKTmult) in three blocks, each separated by approximately thirty minutes. Again, the results indicated no significant differences in FSKTmult measures or CMJ performance between the two conditions. In conclusion, IPC did not significantly affect neuromuscular (in both studies), endurance (in the first study), or anaerobic (in the second study) performance in these taekwondo athletes. [ABSTRACT FROM AUTHOR]

There are various categorization models of high-intensity interval training (HIIT) in the literature that need to be more consistent in definition, terminology, and concept completeness. In this review, we present a training goal-oriented categorization model of HIIT, aiming to find the best possible consensus among the various defined types of HIIT. This categorization concludes with six different types of HIIT derived from the literature, based on the interaction of interval duration, interval intensity and interval:recovery ratio. We discuss the science behind the defined types of HIIT and shed light on the possible effects of the various types of HIIT on aerobic, anaerobic, and neuromuscular systems and possible transfer effects into competition performance. We highlight various research gaps, discrepancies in findings and not yet proved know-how based on a lack of randomized controlled training studies, especially in well-trained to elite athlete cohorts. Our HIIT "toolbox" approach is designed to guide goal-oriented training. It is intended to lay the groundwork for future systematic reviews and serves as foundation for meta-analyses. [ABSTRACT FROM AUTHOR]

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Abstract Background Daily nutrition plays an important role in supporting training adaptions and endurance performance. The objective of this 10-week study was to investigate the consequences of varying carbohydrate consumption and the glycaemic index (GI) together with an endurance training regimen on substrate oxidation, muscle energy storage and endurance performance under free-living conditions. Sixty-five moderately trained healthy men (29 ± 4 years; VO2 peak 55 ± 8 mL min−1 kg−1) were randomized to one of three different nutritional regimes (LOW-GI: 50–60% CHO with ≥ 65% of these CHO with GI 70 per day, n = 20; LCHF: ≤ 50 g CHO daily, n = 21). Metabolic alterations and performance were assessed at baseline (T0) and after 10 weeks (T10) during a graded exercise treadmill test. Additionally, a 5 km time trial on a 400-m outdoor track was performed and muscle glycogen was measured by magnet resonance spectroscopy. Results Total fat oxidation expressed as area under the curve (AUC) during the graded exercise test increased in LCHF (1.3 ± 2.4 g min−1 × km h−1, p 0.05) and decreased in HIGH-GI (− 1.7 ± 1.5 g min−1 × km h−1, p

The addition of wearable technology during a 3-minute all-out overground running test (3MAOT) could provide additional insights to guide training and coaching strategies. The purpose of this study was to explore the relationships between critical speed (CS) and biomechanical parameters (cadence, stride length, vertical oscillation, stance time, form power, leg spring stiffness, and impact loading rate), and changes in biomechanical parameters throughout the 3MAOT. Sixty-three (male, n=37, female, n=26) recreationally active college-aged (23.4±3.9 years) subjects completed a 3MAOT while wearing a Stryd foot-pod. The correlations between CS and biomechanical parameters were evaluated using Pearson coefficients. Stepwise multiple linear regressions were used to test if biomechanical parameters could predict CS. Stance time and impact loading rate explained 69% and 63% of the variance in CS, respectively (R²=0.69, p<0.05; R²=0.63, p<0.05). Step-wise multiple linear regression analysis indicated that vertical oscillation, stance time, form power, leg spring stiffness, and impact loading rate explained 90% of the variance in CS (R²=0.90, p<0.05). Throughout the 3MAOT, changes in cadence (-29%), stride length (57%), vertical oscillation (-8%), stance time (82%), form power (-5%), leg spring stiffness (-24%), and impact loading rate (-48%) were observed. Interventions such as auditory cueing or training designed to improve CS should focus on maintaining large impact loading rates and short stance times, and efforts should be made to enhance an athlete's ability to maintain cadence, leg spring stiffness, vertical oscillation, and form power throughout the 3MAOT. [ABSTRACT FROM AUTHOR]

Astaxanthin, a potent antioxidant found in marine organisms such as microalgae and krill, may offer ergogenic benefits to endurance athletes. Originally used in fish feed, astaxanthin has shown a greater ability to mitigate various reactive oxygen species and maintain the structural integrity of mitochondria compared to other exogenous antioxidants. More recent work has shown that astaxanthin may improve: (1) cycling time trial performance, (2) cardiorespiratory measures such as submaximal heart rate during running or cycling, (3) recovery from delayed-onset muscle soreness, and (4) endogenous antioxidant capacity such as whole blood glutathione within trained populations. In this review, the history of astaxanthin and its chemical structure are first outlined before briefly describing the various adaptations (e.g., mitochondrial biogenesis, enhanced endogenous antioxidant capacity, etc.) which take place specifically at the mitochondrial level as a result of chronic endurance training. The review then concludes with the potential additive effects that astaxanthin may offer in conjunction with endurance training for the endurance athlete and offers some suggested practical recommendations for athletes and coaches interested in supplementing with astaxanthin. [ABSTRACT FROM AUTHOR]

Photobiomodulation therapy (PBMT) has been advocated as a potential intervention to improve muscle performance and recovery in the health and sports context. However, the short- and long-term effects of PBMT on endurance running performance remain under-researched and controversial. The purpose of this study was to investigate the acute dose-response effect of PBMT with light-emitting diodes (LEDs) on endurance performance and rating of perceived exertion (RPE; 6–20 Borg) during a 5-km running trial in recreational runners. In a crossover design, eighteen young adult runners (28.7 ± 7.8 years) were randomized to receive 1 of 4 PBMT conditions (placebo, 300, 900, and 1260 Joules [J]) 60 min before the 5-km running trial on four occasions, separated by a 2-wk washout period. The treatments were applied to the quadriceps, hamstrings, and gastrocnemius muscles of both legs using a device containing 200 LEDs (100 red and 100 infrared). The following variables were assessed: endurance performance (i.e. total time, mean velocity, and velocity in the split distances at the initial 200 m and every 400 m lap) and RPE in the split distances at the initial 200 m and every 400 m lap. Data normality and homogeneity were tested using Shapiro–Wilk's and Levene's tests, respectively. Differences between treatment conditions were assessed using the analysis of variance tests (one- or two-way ANOVA, depending on the comparisons), complemented by the Bonferroni post hoc test. There were significant time effects for the running velocity and RPE in the split distances (p < 0.0001), with no significant treatment-by-time interaction (running velocity, p = 0.59; RPE, p = 0.95). The mean velocity (p = 0.997), total time (p = 0.998), and total mean of the RPE (p = 0.91) were similar between treatment conditions. In conclusion, acute PBMT with LEDs at doses of 300, 900, and 1260 J is not recommended for improving endurance performance and RPE in the 5-km running trial in recreational runners. [ABSTRACT FROM AUTHOR]

During prolonged running at moderate‐to‐high intensity, running economy (RE) deteriorates and attainable maximal oxygen consumption (VO2max) decreases. Whether these changes appear similarly in trained and untrained runners exercising at the same relative intensity is not clear. We recruited 10 trained runners (TR) and 10 active adults (AA), and compared RE and attainable VO2max before and after 1 h of running at 70% of VO2max. Submaximal VO2 increased more (p = 0.019) in AA (0.20 ± 0.13 L min−1) than in TR (0.07 ± 0.05 L min−1). Attainable VO2max decreased in AA (−0.21 ± 0.15 L min−1, p = 0.002), but remained unchanged in TR (−0.05 ± 0.10 L min−1, p = 0.18). Relative intensity (i.e., VO2/attainable VO2max), increased more (p = 0.001) in AA (8.3 ± 4.4%) than in TR (2.6 ± 1.9%). These results demonstrate that the ability to resist changes in RE and VO2max following prolonged running is superior in trained versus untrained runners, when exercising at the same relative intensity. [ABSTRACT FROM AUTHOR]

This study aimed to determine the influence of the testing environment (track vs. treadmill), time trial order (long-short vs. short-long), and timing (within-session vs. between-sessions) on the critical power (CP) and work over CP (W´), using the power metric in runners. Fifteen highly trained athletes performed three test sessions composed of two time trials of 9- and 3-min, separated by a 30-min rest period. One session was performed on a track, and two sessions on a treadmill, alternating the order of the time trials. The CP and W´ values determined on the track were significantly greater and lower than on the treadmill, respectively (p<0.001; CP≥89 W; W´≥3.7 kJ). Their degree of agreement was low (SEE CP>5%; W´>10%) and therefore was not interchangeable. There were no performance differences in the timing of the time trials (p=0.320). Lastly, performing the 9-min trial first resulted in a greater power output compared to when executed last (p<0.001; 4.9 W), although this resulted in similar CP and W´ values (Bias<5 and 10%, respectively). In conclusion, it is feasible to test CP and W´ in a single testing session, irrespective of the time trial order, although not interchangeably between track and treadmill. [ABSTRACT FROM AUTHOR]

Background: Daily nutrition plays an important role in supporting training adaptions and endurance performance. The objective of this 10-week study was to investigate the consequences of varying carbohydrate consumption and the glycaemic index (GI) together with an endurance training regimen on substrate oxidation, muscle energy storage and endurance performance under free-living conditions. Sixty-five moderately trained healthy men (29 ± 4 years; VO2 peak 55 ± 8 mL min−1 kg−1) were randomized to one of three different nutritional regimes (LOW-GI: 50–60% CHO with ≥ 65% of these CHO with GI < 50 per day, n = 24; HIGH-GI: 50–60% CHO with ≥ 65% CHO with GI > 70 per day, n = 20; LCHF: ≤ 50 g CHO daily, n = 21). Metabolic alterations and performance were assessed at baseline (T0) and after 10 weeks (T10) during a graded exercise treadmill test. Additionally, a 5 km time trial on a 400-m outdoor track was performed and muscle glycogen was measured by magnet resonance spectroscopy. Results: Total fat oxidation expressed as area under the curve (AUC) during the graded exercise test increased in LCHF (1.3 ± 2.4 g min−1 × km h−1, p < 0.001), remained unchanged in LOW-GI (p > 0.05) and decreased in HIGH-GI (− 1.7 ± 1.5 g min−1 × km h−1, p < 0.001). After the intervention, LOW-GI (− 0.4 ± 0.5 mmol L−1 × km h−1, p < 0.001) and LCHF (− 0.8 ± 0.7 mmol L−1 × km h−1, p < 0.001) showed significantly lower AUC of blood lactate concentrations. Peak running speed increased in LOW-GI (T0: 4.3 ± 0.4 vs. T10: 4.5 ± 0.3 m s−1, p < 0.001) and HIGH-GI (T0: 4.4 ± 0.5 vs. T10: 4.6 ± 0.4 m s−1), while no improvement was observed in LCHF. Yet, time trial performance improved significantly in all groups. Muscle glycogen content increased for participants in HIGH-GI (T0: 97.3 ± 18.5 vs. T10: 144.5 ± 39.8 mmol L wet-tissue−1, p = 0.027) and remained unchanged in the LOW-GI and the LCHF group. At the last examination, muscle glycogen concentration was significantly higher in LOW-GI compared to LCHF (p = 0.014). Conclusion: Changes in fat oxidation were only present in LCHF, however, lower lactate concentrations in LOW-GI resulted in changes indicating an improved substrate metabolism. Compared to a LCHF diet, changes in peak running speed, and muscle glycogen stores were superior in LOW- and HIGH-GI diets. The low GI diet seems to have an influence on substrate metabolism without compromising performance at higher intensities, suggesting that a high-carbohydrate diet with a low GI is a viable alternative to a LCHF or a high GI diet. Trial registration: Clinical Trials, NCT05241730. https://clinicaltrials.gov/study/NCT05241730. Registered 25 January 2021. Key Points: While only the LCHF diet showed an improvement in fat oxidation and the HIGH-GI group increased peak running speed and showed a trend towards an improvement in time to exhaustion, the LOW-GI group appears to combine both effects on substrate metabolism and performance. Administered under free-living conditions, energy intake changed in LOW-GI diet, possible due to higher intake of fibre, stable insulin levels and associated higher feeling of satiety. Energy intake in HIGH-GI showed no changes and in LCHF a trend towards a reduced intake was observed. While changes in body weight and composition were more pronounced in LOW-GI and LCHF group, muscle energy storage showed beneficial improvements in endurance runners on a high glycaemic index diet. With the muscle glycogen content being significantly lower in LCHF compared to LOW-GI group, it can be assumed that this might be a limiting factor in maximum values for the graded exercise test. [ABSTRACT FROM AUTHOR]

A total of nineteen elite youth cross-country skiers (16 ± 2 years) were divided into three groups: a low-load group (LL, n = 6) performing 15–20 repetitions per exercise, a high-load group (HL, n = 9) executing 6–12 repetitions, and a control group (CON, n = 4) exclusively engaging in endurance training. Testing included 1RM in upper-body exercises, VO2max running tests, and double-poling (DP) ergometer exhaustion and sprint tests to determine peak oxygen uptake (VO2peak-DP) and peak power (PP). The results indicated that HL and LL showed significant increases in VO2peak-DP, both in absolute values (d = −1.2 and −1.2, p < 0.05) and when normalized to body mass (d = 0.93 and 1.3, p < 0.05). Although there were no group*time effects for VO2peak-DP, PP during DP tests to exhaustion increased in both HL (d = −1.6, p < 0.05) and LL (d = 1.4, p < 0.05) compared to CON. Standardized to body mass, only HL showed significant improvements in PP during the sprint test (d = 1.7, p < 0.05). During the sprint test, both absolute and body-mass-normalized peak power increased only in the high-load group (d = −1.0 and 0.93, p < 0.05). In conclusion, high-load resistance training resulted in the greatest improvements in strength, DP performance, and VO2peak-DP, indicating a dose–response relationship to the load magnitude of resistance training. [ABSTRACT FROM AUTHOR]

Chronic alcohol intoxication decreases muscle strength/function and causes mitochondrial dysfunction. Aerobic exercise training improves mitochondrial oxidative capacity and increases muscle mass and strength. Presently, the impact of chronic alcohol on aerobic exercise-induced adaptations was investigated. Female C57BL/6Hsd mice were randomly assigned to one of four groups: control sedentary (CON SED; n = 26), alcohol sedentary (ETOH SED; n = 27), control exercise (CON EX; n = 28), and alcohol exercise (ETOH EX; n = 25). Exercise mice had running wheel access for 2 h a day, 7 days a week. All mice were fed either control or an alcohol-containing liquid diet. Grip strength testing and EchoMRI were performed before and after the interventions. After 6 wk, hindlimb muscles were collected for molecular analyses. A subset of mice performed a treadmill run to fatigue (RTF), then abstained from alcohol for 2 wk and repeated the RTF. Alcohol decreased lean mass and forelimb grip strength compared with control-fed mice. Alcohol blunted the exercise-induced increase in muscle mass (plantaris and soleus), type IIa fiber percentage in the plantaris, and run time to fatigue. Mitochondrial markers (Citrate synthase activity and Complex I-IV, COXIV and Cytochrome C protein expression) were increased with exercise regardless of ETOH in the gastrocnemius but not tibialis anterior muscle. Two weeks of alcohol abstinence improved RTF time in ETOH EX but not in ETOH SED. These data suggest that alcohol impairs some exercise-induced adaptations in skeletal muscle, but not all were negatively affected, indicating that exercise may be a beneficial behavior even while consuming alcohol. NEW & NOTEWORTHY: Alcohol consumption during an aerobic exercise training period prevented training-induced increases in run to fatigue time and grip strength. Cessation of alcohol allowed for recovery of endurance performance within 2 wk. The worsened exercise performance after alcohol was unrelated to impairments in markers of mitochondrial health. Therefore, some adaptations to exercise training are impaired with alcohol use (endurance performance, muscle growth, and strength), while others remain mostly unaffected (mitochondrial health). [ABSTRACT FROM AUTHOR]

Purpose: The critical power (CP) concept has been extended from cycling to the running field with the development of wearable monitoring tools. Particularly, the Stryd running power meter and its 9/3-minute CP test is very popular in the running community. Locating this mechanical threshold according to the physiological landmarks would help to define each boundary and intensity domain in the running field. Thus, this study aimed to determine the CP location concerning anaerobic threshold, respiratory compensation point (RCP), and maximum oxygen uptake (VO2max). Method: A group of 15 high-caliber athletes performed the 9/3-minute Stryd CP test and a graded exercise test in 2 different testing sessions. Results: Anaerobic threshold, RCP, and CP were located at 73% (5.41%), 86.82% (3.85%), and 88.71% (5.84%) of VO2max, respectively, with a VO2max of 66.3 (7.20) mL/kg/min. No significant differences were obtained between CP and RCP in any of its units (ie, in watts per kilogram and milliliters per kilogram per minute; P ≥.184). Conclusions: CP and RCP represent the same boundary in high-caliber athletes. These results suggest that coaches and athletes can determine the metabolic perturbance threshold that CP and RCP represent in an easy and accessible way. [ABSTRACT FROM AUTHOR]

Purpose: To investigate the effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation (HD-tDCS) on physiological and performance responses during exercise at the upper limit of the severe-intensity exercise domain in elite-level road cyclists. Methods: Eleven elite-level road cyclists (VO2peak: 71.8 [3.1] mL·kg−1·min−1) underwent the HD-tDCS or SHAM condition in a double-blind, counterbalanced, and randomized order. After 20 minutes of receiving either HD-tDCS on dorsolateral prefrontal cortex (F3 and F4) or SHAM stimulation, participants completed a 10-minute constant-load trial (CLT1) at 90% of the first ventilatory threshold and a 2-minute CLT (CLT2) at peak power output. Thereafter, they performed a simulated 2-km time trial (TT). Maximal oxygen uptake, respiratory exchange ratio, heart rate, and rating of perceived exertion were recorded during CLT1 and CLT2, whereas performance parameters were recorded during the TT. Results: In 6 out of 11 cyclists, the total time to complete the TT was 3.0% faster in HD-tDCS compared to SHAM. Physiological and perceptual variables measured during CLT1 and CLT2 did not change between HD‐tDCS and SHAM. Conclusions: HD-tDCS over the dorsolateral prefrontal cortex seemed to improve cycling TT performance within the upper limit of the severe-intensity exercise domain, suggesting that an upregulation of the prefrontal cortex could be critical even in this exercise intensity domain. However, the limited dimension and the high interindividual variability require further studies to test these putative ergogenic effects. [ABSTRACT FROM AUTHOR]

The work capacity over critical power is theoretically defined by the curvature constant. However, this parameter has been characterized by a large standard error of the estimate. Therefore, this study aims to determine the validity of this parameter to represent the work performed over critical power on different time trials along the severe intensity domain. Athletes performed four-time trials (3, 5, 10 and 20 min) in a two-week training period on a 400-meter outdoor track. The mean power output of each time trial was measured through the Stryd power meter, and the inverse of the time model was used. The work depletion was modelled in each time trial until exhaustion. The standard error of the estimate was 2.4 (1.0) % for critical power and 12.3 (4.3) % for work over it. Although no significant differences were reported between the work estimated by the critical power model and the one performed on each time trial (P ≥ 0.058), the 95% confidence intervals revealed potential significant discrepancies at the 10-min (−1.4 [−3.1 to 0.3] kJ) and 20-min (2.2 [−0.1 to 4.6] kJ) time trials, respectively. If the work estimated by the critical power model were used, subjects would have reached exhaustion at −8.0 [−19.4 to 3.3] % for the 10-min time trial, and at 13.3 [−2.8 to 29.5] % for the 20-min time trial. Thus, athletes and practitioners are encouraged to consider the specific work of the duration of interest at the severe intensity domain when monitoring with power in running. [ABSTRACT FROM AUTHOR]

Purpose: Several mechanisms have been proposed to explain how mental fatigue degrades sport performance. In terms of endurance performance, a role for an increased perceived exertion has been demonstrated. Using electroencephalography and, more specifically, the movement-related cortical potential (MRCP), the present study explored the neural mechanisms that could underlie the mental fatigue–associated increase in perceived exertion. Methods: Fourteen participants (age, 23 ± 2 yr; 5 women, 9 men) performed one familiarization and two experimental trials in a randomized, blinded, crossover study design. Participants had to complete a submaximal leg extension task after a mentally fatiguing task (EXP; individualized 60-min Stroop task) or control task (CON; documentary). The leg extension task consisted of performing 100 extensions at 35% of 1 repetition maximum, during which multiple physiological (heart rate, electroencephalography) and subjective measures (self-reported feeling of mental fatigue, cognitive load, behand motivation, ratings of perceived exertion) were assessed. Results: Self-reported feeling of mental fatigue was higher in EXP (72 ± 18) compared with CON (37 ± 17; P < 0.001). A significant decrease in flanker accuracy was detected only in EXP (from 0.96 ± 0.03% to 0.03%; P < 0.05). No significant differences between conditions were found in MRCP characteristics and perceived exertion. Specifically in EXP, alpha wave power increased during the leg extension task (P < 0.01). Conclusions: Mental fatigue did not impact the perceived exertion or MRCP characteristics during the leg extension task. This could be related to low perceived exertion and/or the absence of a performance outcome during the leg extension task. The increase in alpha power during the leg extension task in EXP suggests that participants may engage a focused internal attention mechanism to maintain performance and mitigate feelings of fatigue. [ABSTRACT FROM AUTHOR]

Interval training is considered an essential training component in endurance athletes. Recently, there has been a focus on optimization of interval training characteristics to sustain a high fraction of maximal oxygen consumption (≥90% VO2max) to improve physiological adaptations and performance. Herein, we present a synopsis of the latest research exploring both acute and chronic studies in endurance athletes. Further, a decision flowchart was created for athletes and coaches to select the most appropriate interval training regime for specific individualized goals. [ABSTRACT FROM AUTHOR]

To improve performance and recovery faster, athletes are advised to eat more often than usual and consume higher doses of simple carbohydrates, during and after exercise. Sports energetic supplements contain food additives, such as artificial sweeteners, emulsifiers, acidity regulators, preservatives, and salts, which could be harmful to the gut microbiota and impair the intestinal barrier function. The intestinal barrier plays a critical function in bidirectionally regulation of the selective transfer of nutrients, water, and electrolytes, while preventing at the same time, the entrance of harmful substances (selective permeability). The gut microbiota helps to the host to regulate intestinal homeostasis through metabolic, protective, and immune functions. Globally, the gut health is essential to maintain systemic homeostasis in athletes, and to ensure proper digestion, metabolization, and substrate absorption. Gastrointestinal complaints are an important cause of underperformance and dropout during endurance events. These complications are directly related to the loss of gut equilibrium, mainly linked to microbiota dysbiosis and leaky gut. In summary, athletes must be cautious with the elevated intake of ultra-processed foods and specifically those contained on sports nutrition supplements. This review points out the specific nutritional interventions that should be implemented and/or discontinued depending on individual gut functionality. [ABSTRACT FROM AUTHOR]

Ruiz-Alias, SA, Nncupil-Andrade, AA, Pe' rez-Castilla, A, and Garc'ıa-Pinillos, F. Can we predict long-duration running power output? Validity of the critical power, power law, and logarithmic models. J Strength Cond Res 38(2): 306-310, 2024--Predicting long-distance running performance has always been a challenge for athletes and practitioners. To ease this task, different empirical models have been proposed to model the drop of the running work rate with the increase of time. Therefore, this study aims to determine the validity of different models (i.e., CP, power law, and Peronnet) to predict long-duration running power output (i.e., 30 and 60 minutes). In a 4-week training period, 15 highly trained athletes performed 7-time trials (i.e., 3, 4, 5, 10, 20, 30, and 60 minutes) in a randomized order. Then, their power-duration curves (PDCs) were defined through the work-time critical power model (CPwork), power-1/time (CP1/time), 2-parameter hyperbolic (CP2hyp), 3-parameter hyperbolic (CP3hyp), the undisclosed Stryd (CPstryd), and Golden Cheetah (CPcheetah) proprietary models, and the power law and Peronnet models using the 3 to 20 minutes time trials. These ones were extrapolated to the 30- and 60-minute power output and compared with the actual performance. The CP2hyp, CP3hyp, CPstryd, and CPcheetah provided valid 30- and 60-minute power output estimations (#2.6%). The CPwork and CP1/time presented a large predicting error for 30 minutes ($4.4%), which increased for 60 minutes ($8.1%). The power law and Peronnet models progressively increased their predicting error at the longest duration (30 minutes: #21.6%; 60 minutes: #2 6.6%), which was conditioned by the endurance capability of the athletes. Therefore, athletes and practitioners are encouraged to applicate the aforementioned valid models to their PDC to estimate the 30-minute and 60-minute power output. [ABSTRACT FROM AUTHOR]

Acute Ingestion of a Ketone Monoester without Co-ingestion of Carbohydrate Improves Running Economy in Male Endurance Runners. Med. Sci. Sports Exerc., Vol. 56, No. 1, pp. 134-142, 2024. Purpose: Acute ingestion of a ketone monoester, with and without co-ingestion of carbohydrate, was investigated for effects on running economy (RE), time to exhaustion (TTE), and other related indices of endurance running performance. Methods: Using a three condition, placebo-controlled, randomized crossover design, 11 male middle- and long-distance runners ran at five submaximal speeds (10–14 km·h−1 ) on a motorized treadmill for 8 min each, immediately followed by a ramp test to volitional exhaustion. Participants consumed either a 10% carbohydrate solution (CHO), a 10% carbohydrate solution with 750 mg·kg−1 body mass of an (R)-3-hydroxybutyl (R)-3-hydroxybutyrate ketone monoester (CHO + KE), or 750 mg·kg−1 body mass of the ketone monoester in flavored water (KE) before (two-thirds of the dose) and during (one-third of the dose) exercise. Results: β-hydroxybutyrate concentration averaged 1.8 ± 0.3 and 2.1 ± 0.3 mM during exercise in CHO + KE and KE, respectively. RE was lower at each submaximal running speed (effect size = 0.48–0.98) by an average of 4.1% in KE compared with CHO, but not between CHO + KE and CHO. TTE did not differ between CHO (369 ± 116 s), CHO + KE (342 ± 99 s), or KE (333 ± 106 s) (P = 0.093). Conclusions: Acute ingestion of a ketone monoester without carbohydrate, but not when coingested with carbohydrate, improved RE in middle- and long-distance runners at a range of submaximal running speeds and did not alter TTE in a short-duration ramp test to volitional exhaustion. Further investigation is required to examine if these differences translate into positive performance outcomes over longer durations of exercise. [ABSTRACT FROM AUTHOR]

There are various categorization models of high-intensity interval training (HIIT) in the literature that need to be more consistent in definition, terminology, and concept completeness. In this review, we present a training goal-oriented categorization model of HIIT, aiming to find the best possible consensus among the various defined types of HIIT. This categorization concludes with six different types of HIIT derived from the literature, based on the interaction of interval duration, interval intensity and interval:recovery ratio. We discuss the science behind the defined types of HIIT and shed light on the possible effects of the various types of HIIT on aerobic, anaerobic, and neuromuscular systems and possible transfer effects into competition performance. We highlight various research gaps, discrepancies in findings and not yet proved know-how based on a lack of randomized controlled training studies, especially in well-trained to elite athlete cohorts. Our HIIT “toolbox” approach is designed to guide goal-oriented training. It is intended to lay the groundwork for future systematic reviews and serves as foundation for meta-analyses.

This study identified helpful and unhelpful encouragement at mass participation running events and explored the meaning that runners found in encouragement. First, 10 k and half-marathon postevent surveys differentiated instructional and motivational components of helpful and unhelpful support. Second, an inductive, reflexive thematic analysis of 14 interviews highlighted the reciprocal relationship between the crowd and runners, whereby quality of support was reflected in runners' emotions and behavior. Participants drew pride in participation and belief from the crowd, and they wanted to "give back" through doing their best. Personal and authentic support was particularly valued. Although support was widely appreciated, at times it created a pressure to "perform." As a novel intervention based on our combined findings, we recommend that crowds, event organizers, and psyching teams give encouragement "with IMPACT" (Instructional; Motivational; Personalized; Authentic; Confidence-building; Tailored to the distance). Crowds should also demonstrate the "core conditions" of authenticity, empathy, and being nonjudgmental within their encouragement. [ABSTRACT FROM AUTHOR]

This review investigates the effect of two different concurrent training sequences on endurance performance. The sequences investigated are Endurance–Resistance (ER) and Resistance–Endurance (RE). A literature search is conducted of the SPORTDiscus and Medline databases. The included studies are randomized control trials, which compare the effect of ER and RE on at least one endurance performance variable. A PEDro scale is used to assess the methodological quality of the articles in this review. Of a total of 152 articles identified during the initial screening, 15 studies meet the inclusion criteria. These studies include 426 participants (298 males and 128 females), with 212 of the participants training with ER and 214 with RE. The results are presented as the percentage change of the mean from pre- to post-test. All the studies show an improvement in endurance from pre to post for both interventions, except for the RE group in one study. This review finds small and non-conclusive sequence effects between ER and RE, suggesting that the sequence of concurrent training is not of great importance in relation to endurance performance.

There is potential in delivering brief, educational interventions online, particularly for recreational athletes. This initial investigation examined how two online interventions were perceived by endurance participants and how they affected outcomes of interest. After measuring self-efficacy, 142 people were randomized to one of three groups (self-talk, implementation intentions, and control) before an endurance event. Ninety-four completed postevent measures, which were self-efficacy, goal attainment, performance satisfaction, coping, stress appraisals, and social validity. The interventions involved approximately 10 min of initial engagement with online material. Perceptions of stress controllability were significantly higher in the implementation intention group compared with the control. There were no other statistically significant effects. Nevertheless, both intervention groups were satisfied with their interventions, found them useful, and were planning to continue using them. The findings demonstrate the feasibility and value of using brief, online psychological interventions, which may be timely in our changing profession, as COVID-19 has moved many interventions online. [ABSTRACT FROM AUTHOR]

Purpose: To compare the effects of increased load of low- versus high-intensity endurance training on performance and physiological adaptations in well-trained endurance athletes. Methods: Following an 8-week preintervention period, 51 (36 men and 15 women) junior cross-country skiers and biathletes were randomly allocated into a low-intensity (LIG, n = 26) or high-intensity training group (HIG, n = 25) for an 8-week intervention period, load balanced using the overall training impulse score. Both groups performed an uphill running time trial and were assessed for laboratory performance and physiological profiling in treadmill running and roller-ski skating preintervention and postintervention. Results: Preintervention to postintervention changes in running time trial did not differ between groups (P =.44), with significant improvements in HIG (−2.3% [3.2%], P =.01) but not in LIG (−1.5% [2.9%], P =.20). There were no differences between groups in peak speed changes when incremental running and roller-ski skating to exhaustion (P =.30 and P =.20, respectively), with both modes being significantly improved in HIG (2.2% [3.1%] and 2.5% [3.4%], both P <.01) and in roller-ski skating for LIG (1.5% [2.4%], P <.01). There was a between-group difference in running maximal oxygen uptake changes (P =.04), tending to improve in HIG (3.0% [6.4%], P =.09) but not in LIG (−0.7% [4.6%], P =.25). Changes in roller-ski skating peak oxygen uptake differed between groups (P =.02), with significant improvements in HIG (3.6% [5.4%], P =.01) but not in LIG (−0.1% [0.17%], P =.62). Conclusion: There was no significant difference in performance adaptations between increased load of low- versus high-intensity training in well-trained endurance athletes, although both methods improved performance. However, increased load of high-intensity training elicited better maximal oxygen uptake adaptations compared to increased load of low-intensity training. [ABSTRACT FROM AUTHOR]

This study aimed (i) to compare the critical power (CP) and work capacity over CP (W´) values reported by the different CP models available in current analysis software packages (Golden Cheetah and Stryd platform), (ii) to locate the CP values in the power-duration curve (PDC), and (iii) to determine the influence of the CP model used on the W´ balance. Fifteen trained athletes performed four time trials (i. e., 3, 5, 10, 20 minutes) to define their PDC through different CP models: work-time (CPwork), power-1/time (CP1/time), Morton hyperbolic (CPhyp), Stryd platform (CPstryd), and Bioenergetic Golden Cheetah (CPCheetah). Three additional time trials were performed: two to locate the CP values in the PDC (30 and 60 minutes), and one to test the validity of the W' balance model (4 minutes). Significant differences (p<0.001) were reported between models for the estimated parameters (CP, W´). CPcheetah was associated with the power output developed between 10 to 20 minutes, CP1/time , CPstryd CPwork and CPhyp. The W´ reported by the three-parameter CP models overestimated the actual 4 minutes time to exhaustion, with CPwork (0.48 [− 0.19 to 1.16] minutes); and CP1/time (0.40 [− 0.13 to 0.94] minutes) being the only valid models (p≥0.240). [ABSTRACT FROM AUTHOR]

The anisotropy of mechanical properties in SLMed alloy is very important. In order to realize the homogeneity of the microstructure and mechanical properties of GH3536 alloy prepared by selective laser melting (SLM), the as-deposited samples were treated by hot isostatic pressing and then forged at different temperatures. The microstructure, grain size, room- and high- temperature tensile properties, and endurance properties of the samples were studied. The results showed that the microstructure of the sample was mainly equiaxed austenite phase, and granular carbides were precipitated inside the grains after forging treatment, resulting in the anisotropy of the sample almost disappearing. The grain boundary phase difference distribution was most concentrated at 60°. The grain size was less than 10 μm, and a large number of twins were formed. With the increase in forging temperature, the yield strength, tensile strength, and contraction of area of the samples changed little, and the properties parallel to the z-axis (parallel samples) and vertical to the z-axis (vertical samples) were almost the same. In particular, the yield strength, tensile strength, and contraction of area in the transverse and vertical samples were almost at the same level. Judging from the elongation after fracture and the contraction of area, the properties of the samples showed characteristics of anisotropy after a high temperature endurance test. [ABSTRACT FROM AUTHOR]

Although tyrosine supplementation is well recognized to improve cognitive function, its impact on endurance performance is debatable and needs to be clarified further. The purpose of this systematic review and meta-analysis was to evaluate the effects of tyrosine supplementation on whole-body endurance performance in physically active population. The search strategy follow the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA), using four databases (Cochrane Library, Web of Science, Scopus, PsycINFO, and PubMed) until 3 August 2023. The effect of tyrosine (experimental condition) was compared against placebo (control condition). The methodological quality of the included studies was evaluated using the Physiotherapy Evidence Database (PEDro) scale. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE Pro software) System was also used to assess the quality of evidence. A total of 10 interventions from 8 studies were included. The sub-group analysis revealed no significant differences between tyrosine and placebo conditions for time to exhaustion (SMD = 0.02; p = 0.94) and time trial performance (SMD = -0.04; p = 0.85). The level of evidence as qualified with GRADE was moderate. In conclusion, moderate-quality evidence suggests that tyrosine supplementation is ineffective on endurance performance in the physically active population, independently of the endurance task (TTE or ETT). [ABSTRACT FROM AUTHOR]

Ruiz-Alias, SA, Pe' rez-Castilla, A, Soto-Hermoso, VM, and Garc'ıa-Pinillos, F. Influence of the world athletics stack height regulation on track running performance. J Strength Cond Res 37(11): 2260-2266, 2023--A new footwear regulation based on limiting the stack height (i.e., amount of material between the feet and the ground) has been established byWorld Athletics to ensure that performance is achieved through the primacy of human effort over technology in running shoes. Analyzing the effect of legal and illegal shoes on running performance is therefore needed to determine its effectiveness. Thus, this study aimed (a) to compare the effect of 2 footwear models categorized as legal and illegal by the World Athletics regulation on track running performance and (b) to analyze the derived metrics of the athletes' biomechanics when using each footwear model at racing paces. Within 1 week, 14 highly trained athletes performed 2 testing sessions composed of 2 time trials of 9- and 3-minute duration with 30 minutes of recovery between them. The athletes wore the "Nike ZoomX Dragonfly" track spikes model and the "Nike ZoomX Vaporfly Next % 2" marathon shoe model in a counterbalanced randomized order. The results revealed that (a) there was only a small worthwhile improvement in the 3-minute time trial when using themarathon shoes of 0.97%(20.04 to 1.98%) and (b) there was amain effect of footwear in 7 of the 9 biomechanical variables analyzed (p # 0.050). The ground contact time was the unique performance predictor (p 5 0.005, adjusted R2 5 0.476). Altogether, the use of legal and illegal running shoes altered the runners form, which only influenced the mid-distance performance. [ABSTRACT FROM AUTHOR]

RNA sequencing makes it possible to uncover genetic mechanisms that underlie certain performance traits. In order to gain a deeper insight into the genetic background and biological processes involved in endurance performance in horses, the changes in the gene expression profiles induced by endurance runs over long (70 km) and short (15 km) distances in the blood of Kabardian horses (Equus caballus) were analyzed. For the long-distance runs, we identified 1484 up- and 691 downregulated genes, while after short-distance runs, only 13 up- and 8 downregulated genes (FC > |1.5|; p < 0.05) were found. These differentially expressed genes (DEGs) are involved in processes and pathways that are primarily related to stress response (interleukin production, activation of inflammatory system) but also to metabolism (carbohydrate catabolic process, lipid biosynthesis, NADP metabolic process). The most important genes involved in these processes therefore represent good candidates for the monitoring and evaluation of the performance of horses in order to avoid excessive demands when endurance performance is required, like ACOD1, CCL5, CD40LG, FOS, IL1R2, IL20RA, and IL22RA2, on the one hand, and, on the other hand, for assessing the suitability of a horse for endurance races, like GATA2, GYG1, HIF1A, MOGAT1, PFKFB3, PLIN5, SIK1, and STBD1. [ABSTRACT FROM AUTHOR]

When facing a long-distance race, athletes and practitioners could develop an efficient pacing strategy and training paces if an accurate performance estimate of the target distance is achieved. Therefore, this study aims to determine the validity of different empirical models (i.e. critical power [CP], Power law and Peronnet) to predict long-duration power output (i.e. 60 min) when using two or three time trial configurations. In a 5-week training period, fifteen highly trained athletes performed nine-time trials (i.e. 1, 2, 3, 4, 5, 10, 20, 30, and 60 min) in a randomized order. Their power-duration curves were defined through the work-time (CPwork), power-1/time (CP1/time), two-parameter hyperbolic (CP2hyp), three-parameter hyperbolic (CP3hyp) CP models using different two- and three–time trial configurations. The undisclosed proprietary CP models of the Stryd (CPstryd) and Golden Cheetah training software (CPcheetah) were also computed as well as the non-asymptotic Power law and Peronnet models. These were extrapolated to the 60-min power output and compared to the actual performance. The shortest valid configuration (95% confidence interval < 12 W) for CPwork and CP1/time was 3–30 min (Bias: 8.3 [4.9 to 11.7] W), for CPstryd was 10–30 min (Bias: 4.2 [− 1.0 to 9.4] W), for CP2hyp, CP3hyp and CPcheetah was 3-5-30 min (Bias < 5.7 W), for Power law was 1-3-10 min (− 1.0 [− 11.9 to 9.9] W), and for Peronnet was 4–20 min (− 3.0 [− 10.2 to 4.3] W). All the empirical models provided valid estimates when the two or three predicting trial configurations selected attended each model fitting needs. [ABSTRACT FROM AUTHOR]

Carbohydrate supplementation during endurance exercise is known to improve performance, but the effects of food-based approaches in running exercise are understudied. Therefore, this study investigated the performance and gastrointestinal (GI) effects of a carbohydrate supplement containing a natural fructose source compared with a highly processed fructose source in a combined glucose-fructose supplement, during a half-marathon. Eleven trained runners (9 males, 2 females; age 32 ± 8 y, 89:53 ± 13:28 min half-marathon personal record) completed a familiarisation (8 miles) and two experimental trials (13.1 miles) on an outdoor running course, with blood and urine samples collected before and after the run. Subjective GI measures were made throughout the run. Carbohydrate was provided as a natural fructose source in the form of apple puree (AP) or highly processed crystalline fructose (GF) in a 2:1 glucose-to-fructose ratio (additional required glucose was provided through maltodextrin). Half-marathon performance was not different between carbohydrate sources (AP 89:52 ± 09:33 min, GF 88:44 ± 10:09 min; P = 0.684). There were no interaction effects for GI comfort (P = 0.305) or other GI symptoms (P ≥ 0.211). There were no differences between carbohydrate sources in ad libitum fluid intake (AP 409 ± 206 mL; GF 294 ± 149 mL; P = 0.094) or any other urinary (P ≥ 0.724), blood-based (P ≥ 0.215) or subjective (P ≥ 0.421) measures. Apple puree as a natural fructose source was equivalent to crystalline fructose in supporting half-marathon running performance without increasing GI symptoms. Highlights Research examining food-first and food-based approaches to carbohydrate supplementation and endurance running performance are limited. Therefore, this study aimed to compare carbohydrate supplements either containing a natural or highly processed fructose source as part of a glucose-fructose supplement on half-marathon running performance and gastrointestinal comfort in trained runners. Running performance (apple puree 89:52 ± 09:33 min vs. crystalline fructose 88:44 ± 10:09 min), gastrointestinal comfort and symptoms were not different between the two fructose sources. Apple puree can be effectively used as a carbohydrate source to fuel half-marathon running performance. [ABSTRACT FROM AUTHOR]

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We examined if carbohydrate (CHO) mouth rinse may reduce central fatigue and perceived exertion, thus improving maximal incremental test (MIT) performance. Nine recreational cyclists warmed up for 6 min before rinsing a carbohydrate (CHO) or placebo (PLA) solution in their mouth for 10 s in a double-blind, counterbalanced manner. Thereafter, they performed the MIT (25 W·min−1 increases until exhaustion) while cardiopulmonary and ratings of perceived exertion (RPE) responses were obtained. Pre- to post-MIT alterations in voluntary activation (VA) and peak twitch torque (Tw) were determined. Time-to-exhaustion (p = 0.24), peak power output (PPO; p = 0.45), and V̇O2MAX (p = 0.60) were comparable between conditions. Neither treatment main effect nor time–treatment interaction effect were observed in the first and second ventilatory threshold when expressed as absolute or relative V̇O2 (p = 0.78 and p = 0.96, respectively) and power output (p = 0.28 and p = 0.45, respectively) values, although with moderate-to-large effect sizes. RPE increased similarly throughout the tests and was comparable at the ventilatory thresholds (p = 0.56). Despite the time main effect revealing an MIT-induced central and peripheral fatigue as indicated by the reduced VA and Tw, CHO mouth rinse was ineffective in attenuating both fatigues. Hence, rinsing the mouth with CHO was ineffective in reducing central fatigue, lowering RPE, and improving MIT performance expressed as PPO and time-to-exhaustion. However, moderate-to-large effect sizes in power output values at VT1 and VT2 may suggest some beneficial CHO mouth rinse effects on these MIT outcomes.

Ischemic preconditioning (IPC), which involves episodes of blood flow restriction followed by reperfusion, has uncertain effects on athletes. Additionally, employing sports-specific tests that are highly familiar to athletes can enhance methodological rigor in determining IPC’s effects on taekwondo performance. This study aimed to investigate IPC’s influence on taekwondo athletes’ performance through two studies. To induce occlusion in both studies, the cuff was inflated to an individualized occlusion pressure established for each athlete’s lower limb, with four cycles of occlusion lasting five minutes each, alternated with five-minute reperfusion intervals. Both traditional frequentist statistics and Bayesian analysis were employed. In the first study, eleven high-level athletes were subjected to either IPC or a placebo (SHAM) procedure on both legs, followed by performing countermovement jumps (CMJs) and a specific taekwondo endurance test. However, no significant differences were observed in taekwondo endurance performance or CMJ between the IPC and SHAM conditions. The second study involved fourteen elite athletes who underwent the same IPC or SHAM conditions, performing CMJ and three bouts of the Multiple Frequency Speed of Kick test (FSKTmult) in three blocks, each separated by approximately thirty minutes. Again, the results indicated no significant differences in FSKTmult measures or CMJ performance between the two conditions. In conclusion, IPC did not significantly affect neuromuscular (in both studies), endurance (in the first study), or anaerobic (in the second study) performance in these taekwondo athletes.

Astaxanthin, a potent antioxidant found in marine organisms such as microalgae and krill, may offer ergogenic benefits to endurance athletes. Originally used in fish feed, astaxanthin has shown a greater ability to mitigate various reactive oxygen species and maintain the structural integrity of mitochondria compared to other exogenous antioxidants. More recent work has shown that astaxanthin may improve: (1) cycling time trial performance, (2) cardiorespiratory measures such as submaximal heart rate during running or cycling, (3) recovery from delayed-onset muscle soreness, and (4) endogenous antioxidant capacity such as whole blood glutathione within trained populations. In this review, the history of astaxanthin and its chemical structure are first outlined before briefly describing the various adaptations (e.g., mitochondrial biogenesis, enhanced endogenous antioxidant capacity, etc.) which take place specifically at the mitochondrial level as a result of chronic endurance training. The review then concludes with the potential additive effects that astaxanthin may offer in conjunction with endurance training for the endurance athlete and offers some suggested practical recommendations for athletes and coaches interested in supplementing with astaxanthin.