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3 results on '"electrochemical tools"'

1. Determination of Folic Acid Using Biosensors—A Short Review of Recent Progress

Author

Alessio Di Tinno, Rocco Cancelliere, and Laura Micheli

Subjects
folic acid, real samples, analytical methods, electrochemical tools, Chemical technology, TP1-1185
Abstract

Folic acid (FA) is the synthetic surrogate of the essential B vitamin folate, alternatively named folacin, pteroylglutamic acid or vitamin B9. FA is an electroactive compound that helps our body to create and keep our cells healthy: it acts as the main character in a variety of synthetic biological reactions such as the synthesis of purines, pyrimidine (thus being indirectly implied in DNA synthesis), fixing and methylation of DNA. Therefore, physiological folate deficiency may be responsible for severe degenerative conditions, including neural tube defects in developing embryos and megaloblastic anaemia at any age. Moreover, being a water-soluble molecule, it is constantly lost and has to be reintegrated daily; for this reason, FA supplements and food fortification are, nowadays, extremely diffused and well-established practices. Consequently, accurate, reliable and precise analytical techniques are needed to exactly determine FA concentration in various media. Thus, the aim of this review is to report on research papers of the past 5 years (2016–2020) dealing with rapid and low-cost electrochemical determination of FA in food or biological fluid samples.

Published
2021
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2. Novel Electrochemical Biosensors for Clinical Assays.

Author

Guerrieri, Antonio and Guerrieri, Antonio

Subjects
Technology: general issues, 1-methoxy-5-ethyl phenazinium ethyl sulfate, Internet of Things, WiFi portable potentiostat, alkaline phosphatase, alternating current electrokinetic effects, amperometric detection, analytical methods, aptamer, bio-functionalization optimization, biomarkers, biomarkers for infectious diseases, biomedical engineering, biosensor, biosensors, breast cancer, capacitive sensing, carbon dots, choline analysis, choline biosensor, choline oxidase, competitive electrochemical immunosensor, cost-effective biosensors, disposable enzyme sensor, dual electrode biosensor, electrochemical biosensor, electrochemical enzyme sensor, electrochemical sensor, electrochemical tools, electrochemistry, electrophysiology, electropolymerized non-conducting polymer, enzyme, enzyme immobilization, flow injection analysis, folic acid, fructosyl peptide oxidase, glucose dehydrogenase, human epididymis protein 4, immobilization, impedance, in situ detection, lab-on-a-chip, labeling, lactate oxidase, magnetic NPs, miRNA sensing, micro-electrode array, molecularly imprinted polymers (MIPs), nanobiosensors, nanomaterial, nanoparticles (NPs), neural circuit recognition, norepinephrine, on-board calibration, optogenetics, overoxidized polypyrrole, overoxidized polypyrrole film, phosphatidylcholine, phosphocholine analysis, phospholipase D assay, point-of-care diagnostics, real samples, self-assembled monolayers (SAMs), signal amplification, simultaneous determination, surface imprinted polymers (SIPs), surface plasmon resonance, tyrosinase, vascular endothelial growth factor, voltammetry, zinc finger protein
Abstract

Summary: Biosensors, i.e., devices where biological molecules or bio(mimetic)structures are intimately coupled to a chemo/physical transducer for converting a biorecognition event into a measurable signal, have recently gained a wide (if not huge) academic and practical interest for the multitude of their applications in analysis, especially in the field of bioanalysis, medical diagnostics, and clinical assays. Indeed, thanks to their very simple use (permitting sometimes their application at home), the minimal sample pretreatment requirement, the higher selectivity, and sensitivity, biosensors are an essential tool in the detection and monitoring of a wide range of medical conditions from glycemia to Alzheimer's disease as well as in the monitoring of drug responses. Soon, we expect that their importance and use in clinical diagnostics will expand rapidly so as to be of critical importance to public health in the coming years. This Special Issue would like to focus on recent research and development in the field of biosensors as analytical tools for clinical assays and medical diagnostics.

3. Determination of Folic Acid Using Biosensors—A Short Review of Recent Progress.

Author

Di Tinno, Alessio, Cancelliere, Rocco, Micheli, Laura, and Guerrieri, Antonio

Subjects
BIOSYNTHESIS, DIETARY supplements, FOLIC acid, ENRICHED foods, ELECTROACTIVE substances, DNA synthesis
Abstract

Folic acid (FA) is the synthetic surrogate of the essential B vitamin folate, alternatively named folacin, pteroylglutamic acid or vitamin B9. FA is an electroactive compound that helps our body to create and keep our cells healthy: it acts as the main character in a variety of synthetic biological reactions such as the synthesis of purines, pyrimidine (thus being indirectly implied in DNA synthesis), fixing and methylation of DNA. Therefore, physiological folate deficiency may be responsible for severe degenerative conditions, including neural tube defects in developing embryos and megaloblastic anaemia at any age. Moreover, being a water-soluble molecule, it is constantly lost and has to be reintegrated daily; for this reason, FA supplements and food fortification are, nowadays, extremely diffused and well-established practices. Consequently, accurate, reliable and precise analytical techniques are needed to exactly determine FA concentration in various media. Thus, the aim of this review is to report on research papers of the past 5 years (2016–2020) dealing with rapid and low-cost electrochemical determination of FA in food or biological fluid samples. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

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