Author: "du Halgouet A" - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"du Halgouet A"' showing total 34 results

Start Over Author "du Halgouet A"

34 results on '"du Halgouet A"'

1. Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice

Author: du Halgouet, Anastasia, Bruder, Kerstin, Peltokangas, Nina, Darbois, Aurélie, Obwegs, David, Salou, Marion, Thimme, Robert, Hofmann, Maike, Lantz, Olivier, and Sagar
Published: 2024
Full Text: View/download PDF

2. Protocol to expand and CRISPR-Cas9 genomic edit murine MAIT cells for subsequent in vivo studies

Author: Anastasia du Halgouet, Aurélie Darbois, Aurélia Alphonse, Thomas Yvorra, Ludovic Colombeau, Raphaël Rodriguez, Olivier Lantz, and Marion Salou
Subjects: Cell culture, Immunology, CRISPR, Science (General), Q1-390
Abstract: Summary: Generating knockout mice for target molecules in specific T cell populations, without subset-specific promoters, is time-consuming and costly. Here, we describe steps for enriching mucosal-associated invariant T cells from the thymus, expanding them in vitro and performing a CRISPR-Cas9 knockout. We then detail procedure for injecting the knockout cells into wounded Cd3ε−/− mice and characterizing them in the skin.For complete details on the use and execution of this protocol, please refer to du Halgouet et al. (2023).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.
Published: 2023
Full Text: View/download PDF

3. Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing

Author: du Halgouet, Anastasia, Darbois, Aurélie, Alkobtawi, Mansour, Mestdagh, Martin, Alphonse, Aurélia, Premel, Virginie, Yvorra, Thomas, Colombeau, Ludovic, Rodriguez, Raphaël, Zaiss, Dietmar, El Morr, Yara, Bugaut, Hélène, Legoux, François, Perrin, Laetitia, Aractingi, Selim, Golub, Rachel, Lantz, Olivier, and Salou, Marion
Published: 2023
Full Text: View/download PDF

4. Longitudinal Bone Loss Occurs at the Radius in CKD

Author: Letavernier, Emmanuel, Ronco, Pierre, Fessi, Hafedh, Daugas, Eric, du Halgouet, Caroline, de La Faille, Renaud, d’Auzac, Christian, Maruani, Gerard, Vallet, Marion, Gauci, Cédric, Haymann, Jean Philippe, Thervet, Eric, Boffa, Jean-Jacques, Vrtovsnik, François, Froissart, Marc, Stengel, Bénédicte, Nicolet-Barousse, Laurence, Roland, Mélanie, Jacquot, Christian, Cailleaux, Pierre-Emmanuel, Ostertag, Agnes, Metzger, Marie, Boucquemont, Julie, Houillier, Pascal, Flamant, Martin, Ureña-Torres, Pablo, and Cohen-Solal, Martine
Published: 2021
Full Text: View/download PDF

5. Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

Author: Abbassi, Abdelhamid, Debure, Alain, Guerraoui, Abdallah, Benmoussa, Abdelatif, Hamani, Abdelaziz, Ziane, Abdelaziz, Nefti, Abdelhamid, Hadj, Abdelkader, El Amari, Abderrahim, Ghazali, Abderrahmane, Abd El Fatah Mohamed, Abo Bakr, Laradi, Achour, Ben Ahmed, Adel, Sahar, Adel, Pillet, Adele, Lacraz, Adeline, Moinat, Adnan, Massoumi, Afshin, Pardon, Agathe, Beaudoin, Agnes Caillette, Debout, Agnes Chapelet, Mariot, Agnes, Rachi, Ahmed, Afiani, Aida, Boula, Aime Remy, Jalaby, Al, Cremault, Alain, Fournier, Alain, Jeanson, Alain, Lyon, Alain, Nony, Alain, Robert, Alain, Slingeneyer, Alain, Labatide, Alanor Agnes, Sartorius, Albane Brodin, Bensman, Albert, Fournier, Albert, Ranlin, Alex, Sandor, Alex Vido, Colombo, Alexandra, Duhem, Alexandra, Stancu, Alexandra, Dufay, Alexandre, Dumoulin, Alexandre, Ebel, Alexandre, Klein, Alexandre, Martin, Alexandre, Mouneimne, Alexandre, Seidowsky, Alexandre, De Martin, Alfio, Zannier, Alfredo, Aizel, Ali, Hafi, Ali, Diddaoui, Ali Zineddine, Heyani, Alim, Mocanu, Alina, Preda, Alina, Hafi, Aline, Talaszka, Aline, Duquesne, Alyette, Amaouche, Amar, Ghemmour, Amel, Simon, Amelie, Skalli, Amina, Boukadida, Amine, Ragab Eid, Amr Ekhlas, Fedorca, Ana, Baillet, Anabelle, Poyet, Anais, Giorgita, Ancuta Bouffandeau, Ratsimbazafy, Anderson, Pruna, Andre, Argiles, Angel, Testa, Angelo, Vandooren, Ann Karolien, Jolivot, Anne, Labadens, Anne Kolko, Lataste, Anne, Maisin, Anne, Paris, Anne, Sechet, Anne, Wuillai, Anne, Heng, Anne Elisabeth, Josse, Anne Gaelle, Querard, Anne Helene, Reboux, Anne Helene, Adra, Anne Laure, Faller, Anne Laure, Leclerc, Anne Laure, Poitou, Anne Laure, Manucci, Annie Lahoche, Jacquet, Antoine, Pommereau, Antoine, Thierry, Antoine, Adem, Arezki, Chapelet, Arielle, Del Bello, Arnaud, Delezire, Arnaud, Garnier, Arnaud, Guerard, Arnaud, Klisnick, Arnaud, Lionet, Arnaud, Roccabianca, Arnaud, Stolz, Arnaud, Capdeville, Arthur, Allal, Asma, Alrifai, Assem, Diarrassouba, Assetou, Djema, Assia, Carre, Assia Ferhat, Dubrasquet, Astrid Godron, Elmrabet, Atman Haddj, Jegado, Audrey, Thomas, Aurelia Bertholet, Salandre, Aurelie Davourie, Pajot, Aurelie, Lorthioir, Aurelien, Tiple, Aurelien, Sury, Aurore, Abokasem, Ayman, Sarraj, Ayman, Henaoui, Bachir, Chaghouri, Baher, Wehbe, Bassem, Ball, Beatrice, Viron, Beatrice, Issad, Belkassem, Corne, Benedicte Hodemon, Janbon, Benedicte, Deroure, Benjamin, Savenkoff, Benjamin, Jonon, Benoit, Vendrely, Benoit, Djelaleddine, Benyakoub, Ohry, Bernard, Painchart, Bernard, Strullu, Bernard, Temperville, Bernard, Ebikili, Bertin, Hacq, Bertrand, Morel, Bertrand, Aoun, Bilal, Muniz, Blanca, Chlih, Bouchra, Amara, Brahim, Mayor, Brice, Gilson, Brigitte, Llanas, Brigitte, Zins, Brigitte, Bourgeon, Bruno, Coevoet, Bruno, Guery, Bruno, Legallicier, Bruno, Paris, Bruno, Ranchin, Bruno, Seigneuric, Bruno, Dita, Camelia Ghiciuc, Prelipcean, Camelia, Hottelart, Carine Achard, Diet, Carine, Frangie, Carlos, Vela, Carlos, Muresan, Carmina, Deprele, Carole, Araujo, Caroline, Bidault, Caroline, Creput, Caroline, Delclaux, Caroline, Du Halgouet, Caroline, Favennec, Caroline, Freguin, Caroline, Vercel, Caroline Gourraud, Mesguen, Caroline, Obama, Caroline Ndomo, Poitou, Caroline, Dirhold, Caroline Preissig, Roubiou, Caroline, Albert, Catherine, Bessin, Catherine, De Marion Gaja, Catherine, Godart, Catherine, Lasseur, Catherine, Leocardi, Catherine, Lumbroso, Catherine, Melander, Catherine, Michel, Catherine, Maurouard, Catherine Quere, Rouannet, Catherine, Taddei, Catherine, Verove, Cathy, Guiraud, Cecile, Tafelin, Cecile, Baron, Cecile Turc, Formet, Cedric, Pinier, Cedric, De Ste Foy, Celia Lessore, Granolleras, Celine, Bennini, Chaouki, Cartou, Charles, Chazot, Charles, Jouzel, Charlotte, Badid, Cherif, Roubicek, Christa, Viaud, Christel, Verrier, Christelle, Chuet, Christian, Combe, Christian, Dabot, Christian, Duvic, Christian, Emond, Christian, Lagarde, Christian, Lamotte, Christian, Pain, Christian, Mousson, Christiane, Lorriaux, Christie, Beauchamp, Christine, Fumeron, Christine, Le Gurun, Christine, Leroy, Christine, Pietrement, Christine, Richer, Christine, Bouaka, Christophe, Charasse, Christophe, Goupy, Christophe, Ridel, Christophe, Castrale, Cindy, Detourne, Cindy, Francois, Clair, Presne, Claire, Trivin, Claire, Von Kotze, Clarissa, Bernard, Claude, Bonniol, Claude, Desvergnes, Claude, Raharivelina, Claude, Nistor, Claudia, Gueret, Claudine, Lloret, Claudine, Saltiel, Claudine, Rosati, Clelia, Rabate, Clementine, Stanescu, Corina, Ferrandini, Corinne, Guibergia, Corinne, Lemoine, Corinne, Passeron, Corinne, Kahil, Cynthia, Garrouste, Cyril, Van, Cyril Vo, Jolimoy, Cyrille, Kesraoui, Dalila, Jolly, Damien, Thibaudin, Damien, Teboulle, Dan, Daubresse, Daniel, Louvet, Daniel, Rasamimanantsoa, Daniel, Toledano, Daniel, Babici, Daniela, David, Daniela, Dincu, Daniela, Bruno, Danielle, May, Delia, Haussaire, Delphine, Viprey, Delphine Henriet, Bugnon, Denis, Fouque, Denis, Morin, Denis, Nour, Derradji, Mahmoud, Diab Mohamed, Cristescu, Diana Istrati, Aguilera, Didier, Coste, Didier, Hamel, Didier, Le Chapois, Didier, Testou, Didier, Erbilgin, Dilaver, Dahmane, Djamal, Quang, Doan Bui, Bertrand, Dominique, Besnier, Dominique, Blanchier, Dominique, Briffa, Dominique, Caux, Dominique, Durand, Dominique, Fleury, Dominique, Guerrot, Dominique, Hestin, Dominique, Jaubert, Dominique, Joly, Dominique, Lombart, Dominique, Pagniez, Dominique, Pierre, Dominique, Schohn, Dominique, Ikonga, Donatien, Visanica, Dorina, Bazin, Dorothee, Boury, Edouard, Maksour, Edouard, Agbonon, Ekoue, Harrami, Elarbi, Marcu, Elena, Tudorache, Elena, Caniot, Elisabeth, Semjen, Elisabeth, Tomkiewicz, Elisabeth, Scheidt, Elise, Gaboriau, Elke, Lamouroux, Elodie, Guiard, Elsa, Passos, Elsa Martin, Nsembani, Emerson, Fache, Emilie, Kalbacher, Emilie, Pambrun, Emilie, Pincon, Emilie, Launay, Emma Allain, Baron, Emmanuel, Dupuis, Emmanuel, Villar, Emmanuel, Charlin, Emmanuelle, Hecquet, Emmanuelle, Kohler, Emmanuelle, Laurain, Emmanuelle, Rosier, Emmanuelle, Figueroa, Enrique, Azoulay, Eric, Canivet, Eric, Daugas, Eric, Gauthier, Eric, Laruelle, Eric, Le Guen, Eric, Legrand, Eric, Moumas, Eric, Postec, Eric, Prinz, Eric, Renaudineau, Eric, Desport, Estelle, Sutra, Estelle Ricard, Berard, Etienne, Ged, Etienne, Robin, Etienne, Vilaine, Eve, Bargas, Evelyne, Namara, Evelyne Mac, Combarnous, François, Yazbeck, Fatima, Gerard, Fabien, Metivier, Fabien, Parazols, Fabien, Soulis, Fabien, Garnier, Fabrice, Messaoudene, Fadhila Pech, Haidar, Fadi, Boullenger, Fanny, Lepeytre, Fanny, Leroy, Fanny, Frejate, Fares, Bellahsene, Farid, Bellhasene, Farid, Saidani, Farid, Toure, Fatouma, Kriaa, Faycal, Nemmar, Fazia, Vetromile, Fernando, Chalmin, Florence, Lucats, Florence, Sens, Florence, Villemain, Florence, Plasse, Florent, Lebhour, Fouad, Schillinger, Francis, Berge, Franck, Bourdon, Franck, Bridoux, Franck, Reynaud, Franck, Babinet, Francois, Basse, Francois, Chantrel, Francois, Clair, Francois, Coulomb, Francois, De Cornelissen, Francois, Glowacki, Francois, Marchal, Francois, Maurice, Francois, Nobili, Francois, Pourreau, Francois, Provot, Francois, Amani, Francois Roux, Broux, Francoise, Bulte, Francoise, Heibel, Francoise, Leonetti, Francoise, Schott, Francoise Moussion, Le Roy, Frank, Besson, Frederic, Lavainne, Frederic, Tollis, Frederic, Bocquentin, Frederique, Meeus, Frederique, Vecina, Frederique, Von Ey, Friederike, Balit, Gabriel, Choukroun, Gabriel, Gruget, Gabriel, Huchard, Gabriel, Golea, Gabriella, Duneau, Gabrielle, Lefrancois, Gaelle, Pelle, Gaelle, Lebrun, Gaetan, Dumont, Genevieve, Brillet, Georges, Deschenes, Georges, Mourad, Georges, Stamatakis, Georges, Cazajous, Geraldine, D'ythurbide, Geraldine, Wiart, Geraldine Robitaille, Cardon, Gerard, Champion, Gerard, Deschodt, Gerard, Mangenot, Gerard, Motte, Gerard, Schortgen, Gerard, Boulahia, Ghada, Maakaroun, Ghassan, Michel, Ghylene Bourdat, Zanetta, Gilbert, Hufnagel, Gilles, Messier, Gilles, Piccoli, Giorgina, Desvergnes, Gregoire Couvrat, Bobrie, Guillaume, Bonnard, Guillaume, Clement, Guillaume, Jean, Guillaume, Queffeulou, Guillaume, Seret, Guillaume, Vernin, Guillaume, Delavaud, Guy, Lambrey, Guy, Rostoker, Guy, Poussard, Gwenaelle, Kesler, Gwenaelle Roussey, Leon, H., Aboubekr, Habib, Boulechfar, Hacene, Sekhri, Hacene, Hebibi, Hadia, Benalia, Hadjira, Fessi, Hafed, Atchia, Hafsabhai, Bittar, Haiat, Maiza, Hakim, Mazouz, Hakim, El Ali, Hamid, Bougrida, Hammouche, Van Der Pijl, Hans, Lokmane, Hassan, Izzedine, Hassane, Adda, Hassen, De Preneuf, Helene, Leray, Helene, Philippot, Helene, Boulanger, Henri, Merault, Henri, Renaud, Henri, Bonarek, Herve, Maheut, Herve, Nzeyimana, Hilaire, Mehama, Hocine, Zaidi, Hocine, Weclawiak, Hugo, Flodrops, Hugues, Karaaslan, Huseyin, Haskour, Ibrahim, Belhadj, Ihssen, Almoubarak, Imad, Haddad, Imad, Castellano, Ines, Ferrandiz, Ines, Daniliuc, Ioana, Darie, Ioana, Enache, Ioana, Prunescu, Ionut, Djiconkpode, Irenee, Shahapuni, Irina, Bouchoule, Isabelle, Devriendt, Isabelle, Kazes, Isabelle, Kolb, Isabelle, Landru, Isabelle, Poli, Isabelle, Rey, Isabelle, Segalen, Isabelle, Selcer, Isabelle, Vernier, Isabelle, Vrillon, Isabelle, Guenifi, Ismahane, Gheerbrandt, J. Dominique, Potier, Jacky, Becart, Jacques, Cledes, Jacques, Ducros, Jacques, Duvic, Jacques, Fourcade, Jacques, Gaultier, Jacques, Jurine, Jacques, Lebleu, Jacques, Ollier, Jacques, Charles, Jacques Ibsen, Yazji, Jamal, Mansour, Janette, Arnautou, Jean, Brocard, Jean, Carolfi, Jean, Montoriol, Jean, Gouin, Jean Baptiste, Palcoux, Jean Bernard, Bendini, Jean Christophe, Aldigier, Jean Claude, Alphonse, Jean Claude, Delbet, Jean Daniel, Bonne, Jean Francois, Cantin, Jean Francois, De Fremont, Jean Francois, Dessassis, Jean Francois, Subra, Jean Francois, Valentin, Jean Francois, Verdier, Jean Francois, Dion, Jean Jacques, Haultier, Jean Jacques, Montseny, Jean Jacques, Bacri, Jean Louis, Bouchet, Jean Louis, Mahe, Jean Luc, Chalopin, Jean Marc, Gabriel, Jean Marc, Hurot, Jean Marc, Lanau, Jean Marc, Batho, Jean Marie, Coulibaly, Jean Marie, Hardin, Jean Michel, Marc, Jean Michel, Poux, Jean Michel, Rebibou, Jean Michel, Tivollier, Jean Michel, Ottavioli, Jean Noel, Faucon, Jean Paul, Imiela, Jean Paul, Jaulin, Jean Paul, Masselot, Jean Paul, Ortiz, Jean Paul, Bourdenx, Jean Philippe, Devaux, Jean Philippe, Hammelin, Jean Philippe, Rivory, Jean Pierre, Wauquier, Jean Pierre, Larue, Jean Rene, Mondain, Jean Rene, Borde, Jean Sebastien, Virot, Jean Simon, Bosc, Jean Yves, Achiche, Jedjiga, Parasote, Jennifer, Diolez, Jeremie, Harambat, Jerome, Potier, Jerome, Sampol, Jerome, Mustel, Jihad, Lefevre, Jean Jacques, Maurizi, Jocelyne, Gamberoni, Joel, Claudeon, Joelle, Terzic, Joelle, Rogol, Joffrey, Sayegh, Johnny, Cardozo, Jorge, Brasseur, Jose, Guiserix, Jose, Barsumau, Joseph, Albaret, Julie, Beaume, Julie, Attias, Julie Sohier, Dehay, Julien, Hogan, Julien, Journet, Julien, Ott, Julien, Baleynaud, Juliette, Bacchetta, Justine, Faucher, Justine, Yousfi, Kamel, Dardim, Karim, Clabault, Karine, Moreau, Karine, Thomas, Kedna, Sirajedine, Khaled, Chedid, Khalil, El Kaeoui, Khalil, El Karoui, Khalil, Bouachi, Khedidja, Hue, Kheira, El Nasser, Khuzama, Akposso, Kodso, Kunz, Kristian, Bijak, Krzysztof, Kihal, Lilia, Rasoloarijaona, L., Harbouche, Laid, Bencheikh, Larbi, Lamriben, Larbie, Hanafi, Latifa, Parvez, Laura Braun, Champion, Laure, Croze, Laure, Eprinchard, Laure, Patrier, Laure, Nicolet, Laurence, Vrigneaud, Laurence, Duflot, Laurent, Mackaya, Leandre, Chenine, Leila, Odry, Leon, Tamiji, Lili Taghipour, Bouzar, Lilia Antri, Nga Messi, Liliane Ngango, Le Mouellic, Lionel, Mandart, Lise, Weis, Lise, Pouteau, Lise Marie, Georgieva, Lora, Vitanova, Lorita, Chalabi, Lotfi, Delvallez, Luc, Frimat, Luc, Fromentin, Luc, Marty, Luc, Monjot, Luc, Spataru, Luciana, Bessenay, Lucie, Boissinot, Lucie, Wajsbrot, Lucie, Rakoff, Lucien, Lebourg, Ludivine, Perez, Lydie, Lafage, Lyliane, Azzouz, Lynda, Dumoulin, Madeleine, Ouziala, Messaoud, Joseph, Maan, Brahimi, Mabrouk, Fat, Maeva Wong, Fort, Magalie, Nakhla, Magued, Abtahi, Mahdi, Albadawy, Mahen, Alouach, Mahmoud, Mezghani, Mahmoud, Daroux, Maite, Boukelmoune, Maklouf, Dhib, Malek, Touam, Malik, Dubau, Malina, Balde, Mamadou, Khoa, Man Nguyen, Ismer, Manfred, Mehdi, Manolie, Laforet, Manon, Bouiller, Marc, Eugene, Marc, Fila, Marc, Hazzan, Marc, Kribs, Marc, Ladriere, Marc, Lebot, Marc, Padilla, Marc, Souid, Marc, Marraoui, Marcel, Burbach, Maren, Manescu, Maria, Noguera Gonzalez, Maria Eugenia, Revenco, Mariana, Terrasse, Marianne, Essi, Marie, Macher, Marie Alice, Nogier, Marie Beatrice, Cazin, Marie Cecile, Schweitzer Camoin, Marie Christine, Thouret, Marie Christine, Hannaert, Marie Claude, Servel, Marie France, Chabannier, Marie Helene, Coudert Krier, Marie Jeanne, Catoliquot, Marie Noelle, Guillodo, Marie Paule, Gavard, Marie Sophie, Vairon Codaccioni, Marie Xaviere, Rabec, Marina, Freist, Marine, Gauthier, Marion, Lemaire, Marion, Mehrenberger, Marion, Venot, Marion, Pongas, Marios, Diant, Marlene Beaubrun, Levannier, Martial, Bertaux, Martine, Jablonski, Mathieu, Sacquepee, Mathieu, Dargelos, Mathilde, Lemoine, Mathilde, Tamain, Mathilde, Monge, Matthieu, Reberolle, Matthieu, Cousin, Maud, Francois, Maud, Baron, Maurice, Hoffmann, Maxime, Ingwiller, Maxime, Touzot, Maxime, Mohajer, Mederick, Maaz, Mehadji, Hanoy, Melanie, Marroc, Melanie, Cuny, Melodie, Van Der Straaten, Menno, Serveaux, Mf., Basteri, Michel, Chong, Michel Fen, Hecht, Michel, Massad, Michel, Normand, Michel, Olmer, Michel, Tolani, Michel, Tsimaratos, Michel, Hemery, Michele, Kessler, Michele, Esposito, Miguel, Shenouda, Milad, Kareche, Mimi, Khalili, Mina, Diaconita, Mirella, Rifard, Mohamad Khair, Aladib, Mohamed, Belmouaz, Mohamed, Brahim, Mohamed, Diouani, Mohamed, Cherif, Mohamed Fodil, Jamali, Mohamed, Maghlaoua, Mohamed, Meddeb, Mohamed, Ramdane, Mohamed, Rifaat, Mohamed, Islam, Mohamed Sharifull, Abbade, Mohamed Adnan, Amrandi, Mokhtar, Chawki, Mokhtar, Ciobotaru, Monica, Indrieis, Monica, Chanas, Monique, Hoarau, Monique, Tomeh, Monzer, Bellou, Moufida, Bouzernidj, Mouloud, Ammor, Mounia, Guergour, Mounir, Benzakour, Mountassir, Hachicha, Mourad, Coulibaly, Moussa, Smati, Mustafa, Al Morabiti, Mustapha, Amirou, Mustapha, Isnard, Myriam, Pastural, Myriam, Pujo, Myriam, Boumendjel, Nourredine, Majbri, Nabil, Goumri, Nabila, Mingat, Nadege, Bassilios, Nader, Kerkeni, Nadia, Sedrati, Nadia, Soltani, Nadia, Maroun, Nadine, Neyrat, Nadine, Luang, Nahn, El Esper, Najeh, Ammar, Naji, Ghali, Nasredine, Hamdini, Nasser, Noel, Natacha, Potelune, Natacha, Maisonneuve, Nathalie, Pertuiset, Nathalie, Raynal, Nathalie, Vittoz, Nathalie, Terki, Nazim, Castin, Nelly, Nankeu, Nestor, Bouvier, Nicolas, Keller, Nicolas, Legros, Nicolas, Peters, Nicolas, Quirin, Nicolas, Lefrancois, Nicole, Monnier, Nicole, Rance, Nicole, Bruckmann, Niels, Mertens, Noel, Lorcy, Nolwenn, Gilbert, Olivia, Coldefy, Olivier, Drouineau, Olivier, Dunand, Olivier, Fritz, Olivier, Imhoff, Olivier, Kourilsky, Olivier, Lavelle, Olivier, Moranne, Olivier, Papin, Olivier, Roques, Olivier, Le Maner, Ophelie, Benbrahim, Oussamah Fikri, Erina Torres, Pablo Antonio, Urena Torres, Pablo Antonio, Malvezzi, Paolo, Bindi, Pascal, Cluzel, Pascal, Fontanier, Pascal, Wheatley, Pascal, Depraetre, Pascale, Dubosq, Pascale, Halin, Pascale, Sebahoun, Pascale, Siohan, Pascale, Testevuide, Pascale, Deteix, Patrice, Nolen, Patrice, Hue, Patricia, Lemarchand, Patricia, Donnadieu, Patrick, Fievet, Patrick, Fohrer, Patrick, Francais, Patrick, Giraud, Patrick, Hallonet, Patrick, Henri, Patrick, Michaut, Patrick, Niaudet, Patrick, Pauly, Patrick, Thomas, Patrick, Deleaval, Patrik, Finielz, Paul, Stroumza, Paul, Yverneau, Paule Hardy, Caillard, Pauline, Palacin, Pedro, Aubertin, Perrine, Attias, Philippe, Brunet, Philippe, Chauveau, Philippe, Coindre, Philippe, Coste, Philippe, Dubot, Philippe, Fournier, Philippe, Hiernaux, Philippe, Jousset, Philippe, Yue Wah, Philippe Lan, Lang, Philippe, Le Cacheux, Philippe, Dupont, Philippe Martin, Michel, Philippe, Mirgaine, Philippe, Moriniere, Philippe, Nicoud, Philippe, Rieu, Philippe, Rousseau, Philippe, Sporer, Philippe, Thorel, Philippe, Vanhille, Philippe, Vigeral, Philippe, Zaoui, Philippe, Bataille, Pierre, Brignon, Pierre, Filipozzi, Pierre, Housset, Pierre, Peyronnet, Pierre, Ramperez, Pierre, Vautrin, Pierre, Michel, Pierre Alexandre, Westeel, Pierre Francois, Carron, Pierre Louis, Durand, Pierre Yves, Parent, Pierrot, Seniuta, Piotr, Kuentz, François, Fraoui, Rabah, Tetaz, Rachel, Amaria, Rachid, Bourouma, Rachid, Djeffal, Rachid, Nebbad, Rachida, Allal, Radia, Dimulescu, Radu, Boustani, Rafaat, Mesbah, Rafik, Makdassi, Raifat, Diab, Raji, Puslenghea, Raluca, Roura, Raoul, Khayat, Rateb, Azar, Raymond, Frayssinet, Raymond, Monkam, Regine, Boulahrouz, Rehouni, Boudet, Remi, Demontis, Renato, Gansey, Renaud, Cuvelier, Rene, Schmitt, Renee, Noordally, Reschad, Binaut, Reynald, Latif, Rezkallah, Dufresne, Richard, Montagnac, Richard, Reade, Richard, Genin, Robert, Novo, Robert, Fickl, Rocsana, Dufresne, Roger, Magnol, Roger, Issautier, Roland, Mortelette, Romain, Delaval, Ronan, Lohro, Ronan, M'barga, Roseline, Beau, S., Dupuis, Clémentine, Vidil, Marie Jacques, Hacini, Sabria, Dahmoune, Said, Lekhal, Saliha, Sakso, Salima Ahriz, Saksi, Salima, Citarda, Salvatore, Boubenider, Samir, Kassis, Samuel, Verhille, Sandra, Genestier, Sandrine, Muller, Sandrine, Krid, Saoussen, Richter, Sarah, Delbes, Sebastien, Mailliez, Sebastien, Veillon, Sebastien, Nony, Sébastien, Benarbia, Seddick, Beaudreuil, Severine, Benyaghla, Sidi Ali, Duquennoy, Simon, Baluta, Simona, Boncila, Simona, Mzoughi, Sonia, Ribal, Sonia, Acamer, Sophie, Chauvet, Sophie, Girerd, Sophie, Ozenne, Sophie, Parahy, Sophie, Duval, Sophie Rubens, Taque, Sophie, Menouer, Soraya, Chargui, Soumaya, Bataille, Stanislas, Barbier, Stephane, Billion, Stephane, Roueff, Stephane, Torner, Stephane, Martin, Stephane Jean, Coupel, Stephanie, Cloarec, Sylvie, Lavaud, Sylvie, Leou, Sylvie, Chatelet, T., Onesta, Tania, Benhabib, Tassadit, Bensalem, Tayeb, Dimulescu, Theodora, Sawadogo, Theophile, Hitze, Thibault Dolley, Baranger, Thierry, Boudemaghe, Thierry, Hannedouche, Thierry, Krummel, Thierry, Lobbedez, Thierry, Milcent, Thierry, Dervaux, Thomas, Guincestre, Thomas, Kofman, Thomas, Raphael, Thomas, Sadreux, Thomas, Ulinski, Tim, Roger, Tiphaine Guyon, Serrato, Tomas, Kofman, Tomek, Wong, Tony, Boubia, Toufik, Gbindoun, Ubald Assogba, Khuzaie, Usama, Caudwell, Valerie, Chatelet, Valerie, Crougneau, Valerie, De Precigout, Valerie, Drouillat, Valerie, Galantine, Valerie, Hugot, Valerie Granveau, Leroy, Valerie, Boubia, Veronique, Falque, Veronique, Fournier, Veronique, Queron, Veronique, Viviani, Veronique, Gueuttin, Victor, Panescu, Victor, Calonge, Victorio Menoyo, Nguyen, Viet, Allot, Vincent, Delattre, Vincent, Leduc, Vincent, Pradier, Vincent, Aglae, Violaine Emal, Badulescu, Viorica, Molina, Virginia, Besson, Virginie, Chaigne, Virginie, Jaber, Waddah, Boudi, Wael, El Haggan, Wael, Guillon, Wen Qin, Aneni, Wided Tabbi, Hanf, William, Kohn, Wladimir, Bellenfant, Xavier, Gaudry, Xavier Moreau, Delmas, Yahsou, Knefati, Yannick, Saingra, Yannick, Tirolien, Yannick, Mann, Youssef, Brunak, Yvan, Dimitrov, Yves, Doussy, Yves, Tanter, Yves, Benabid, Zaid, Soltani, Zaara, Boukerroucha, Zacharia, Takla, Zafer, Ramanantsialonina, Zana, Dickson, Zara, Tubail, Zead, Pour, Zoe Koochaki, Boukhalfa, Zohra, Jacquot, Zohra, Couchoud, Cécile, Bayer, Florian, Ayav, Carole, Béchade, Clémence, Chantrel, François, Galland, Roula, Hourmant, Maryvonne, and Mercadal, Lucile
Published: 2020
Full Text: View/download PDF

6. Fasting Urinary Osmolality, CKD Progression, and Mortality: A Prospective Observational Study

Author: Livrozet, Marine, Letavernier, Emmanuel, Ronco, Pierre, Fessi, Hafedh, Vidal-Petiot, Emmanuelle, Daugas, Eric, du Halgouet, Caroline, de La Faille, Renaud, Maruani, Gerard, Vallet, Marion, Nicolet-Barousse, Laurence, Karras, Alexandre, Jacquot, Christian, Tabibzadeh, Nahid, Wagner, Sandra, Metzger, Marie, Flamant, Martin, Houillier, Pascal, Boffa, Jean-Jacques, Vrtovsnik, Francois, Thervet, Eric, Stengel, Bénédicte, and Haymann, Jean-Philippe
Published: 2019
Full Text: View/download PDF

7. MAIT cells monitor intestinal dysbiosis and contribute to host protection during colitis.

Author: El Morr, Yara, Fürstenheim, Mariela, Mestdagh, Martin, Franciszkiewicz, Katarzyna, Salou, Marion, Morvan, Claire, Dupré, Thierry, Vorobev, Alexey, Jneid, Bakhos, Premel, Virginie, Darbois, Aurélie, Perrin, Laetitia, Mondot, Stanislas, Colombeau, Ludovic, Bugaut, Hélène, du Halgouet, Anastasia, Richon, Sophie, Procopio, Emanuele, Maurin, Mathieu, and Philippe, Catherine
Subjects: COLITIS, INTESTINES, DYSBIOSIS, LIGANDS (Biochemistry), GUT microbiome
Abstract: Intestinal inflammation shifts microbiota composition and metabolism. How the host monitors and responds to such changes remains unclear. Here, we describe a protective mechanism by which mucosal-associated invariant T (MAIT) cells detect microbiota metabolites produced upon intestinal inflammation and promote tissue repair. At steady state, MAIT ligands derived from the riboflavin biosynthesis pathway were produced by aerotolerant bacteria residing in the colonic mucosa. Experimental colitis triggered luminal expansion of riboflavin-producing bacteria, leading to increased production of MAIT ligands. Modulation of intestinal oxygen levels suggested a role for oxygen in inducing MAIT ligand production. MAIT ligands produced in the colon rapidly crossed the intestinal barrier and activated MAIT cells, which expressed tissue-repair genes and produced barrier-promoting mediators during colitis. Mice lacking MAIT cells were more susceptible to colitis and colitis-driven colorectal cancer. Thus, MAIT cells are sensitive to a bacterial metabolic pathway indicative of intestinal inflammation. Editor's summary: Changes in the gut microbiota have been linked to intestinal inflammation, but how these shifts are sensed by the host is not completely understood. Using an experimental colitis model in mice, El Morr et al. defined a role for mucosal-associated invariant T (MAIT) cells in sensing increases in MAIT ligands associated with the expansion of riboflavin-producing aerotolerant bacteria in the gut lumen. MAIT cells are then activated upon sensing these ligands and produce anti-inflammatory molecules and mediators of tissue repair. In the absence of MAIT cells, mice are more susceptible to colitis pathology and progression to colorectal cancer. —Christiana Fogg [ABSTRACT FROM AUTHOR]
Published: 2024
Full Text: View/download PDF

8. A conserved transcriptional program for MAIT cells across mammalian evolution

Author: Bugaut, Hélène, primary, El Morr, Yara, additional, Mestdagh, Martin, additional, Darbois, Aurélie, additional, Paiva, Rafael A., additional, Salou, Marion, additional, Perrin, Laetitia, additional, Fürstenheim, Mariela, additional, du Halgouet, Anastasia, additional, Bilonda-Mutala, Linda, additional, Le Gac, Anne-Laure, additional, Arnaud, Manon, additional, El Marjou, Ahmed, additional, Guerin, Coralie, additional, Chaiyasitdhi, Atitheb, additional, Piquet, Julie, additional, Smadja, David M., additional, Cieslak, Agata, additional, Ryffel, Bernhard, additional, Maciulyte, Valdone, additional, Turner, James M.A., additional, Bernardeau, Karine, additional, Montagutelli, Xavier, additional, Lantz, Olivier, additional, and Legoux, François, additional
Published: 2023
Full Text: View/download PDF

9. Protocol to expand and CRISPR-Cas9 genomic edit murine MAIT cells for subsequent in vivo studies

Author: du Halgouet, Anastasia, primary, Darbois, Aurélie, additional, Alphonse, Aurélia, additional, Yvorra, Thomas, additional, Colombeau, Ludovic, additional, Rodriguez, Raphaël, additional, Lantz, Olivier, additional, and Salou, Marion, additional
Published: 2023
Full Text: View/download PDF

10. Role of MR1-driven signals and amphiregulin on the recruitment and repair function of skin MAIT cells

Author: de Poulpiquet du Halgouet, Anastasia, primary, Darbois, Aurélie, additional, Alkobtawi, Mansour, additional, Mestdagh, Martin, additional, Premel, Virginie, additional, Colombeau, Ludovic, additional, Rodriguez, Raphaël, additional, Zaiss, Dietmar, additional, Aractingi, Selim, additional, Golub, Rachel, additional, Lantz, Olivier J, additional, and Salou, Marion, additional
Published: 2023
Full Text: View/download PDF

11. In vivo study of MAIT cell tissue repair function

Author: de Poulpiquet Du Halgouet, Anastasia, Immunité et cancer (U932), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris sciences et lettres, Olivier Lantz, and STAR, ABES
Subjects: Réparation, Peau, In vivo, MAIT cells, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.MHEP.DERM] Life Sciences [q-bio]/Human health and pathology/Dermatology, Cellule MAIT, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, Repair, [SDV.MHEP.DERM]Life Sciences [q-bio]/Human health and pathology/Dermatology, Skin
Abstract: The mechanical, chemical, or infectious mediated tissue damages affect all epithelial barriers including the skin. The rapid resolution of theses damages is key to recover their integrity and function, it involves the joint action of several immune cells that infiltrate the barrier tissues. The interest surrounding the study of MAIT (mucosal-associated immune T) cells in repair stems from their high frequency in the skin (up to 10% of T cells) and their capacity to rapidly secrete various effector molecules. Recently, it has been shown both in vitro and in vivo that MAIT cells are involved in wound healing. However, the mechanisms that underly this pro-repair function remain elusive. Using the congenic B6-MAITCAST strain (10 times more MAIT cells than the C57BL/6 mice) and an full thickness excision model mimicking the human repair process (Dunn et al., 2013), we aimed at unravelling these mechanisms. With these tools, we first show that MAIT cells accelerates wound closure. Because MAIT cell numbers and frequency increased following injury without increased proliferation, we hypothesized that MAIT cells were recruited to the wound site. Using skin graft experiments we evidenced that, contrary to the resident gdT cells, MAIT cells are rapidly recruited into the inflamed site. The Kaedes mouse (in which local ultraviolet light induces a shift in fluorescence) strain and the use of FTY720 treatment demonstrated that recruited cells transited through the lymph nodes rather than from the surrounding skin. We next investigated whether TCR signaling, via MR1 the MAIT cell antigen presenting molecule, could be necessary both for the recruitment and the tissue repair function. To investigate MAIT cells reliance on TCR signaling, we performed parabiosis of MR1+ and MR1- animals and MR1- skin grafted onto MR1+ animals, and we showed that MAIT cell recruitment was MR1-independent. Instead, the recruitment relied on the CXCL16-CXCR6 signaling, as shown by blocking CXCL16 in vivo and deleting CXCR6 on MAIT cells by CRISPR-Cas9 genetic modification. Adoptive ransfer experiments further demonstrated that wound closure does not depend on a continuous TCR signaling.Concerning their effector function our scRNAseq analysis suggested that MAIT cell repair program was acquired already at steady state in the skin. Additionally, we observed an increase in epithelial tongue length and proliferation within these tongues in the presence of MAIT cells as compared to their absence. Thus, we presupposed that MAIT cells could play a direct effector function on keratinocyte growth. This theory was supported by scRNAseq that showed that signatures associated to amphiregulin-producing pro-repair cells were up-regulated by skin MAIT cells . We observed that amphiregulin produced by PLZF cells was necessary in our model and that MAIT cells increased its production at the protein level following wounding. Transfer experiments of Areg deficient MAIT cells formally demonstrated that Areg produced by MAIT cells was instrumental for promoting wound repair.Overall, our study describes the dynamics of MAIT cells within the skin, the signals they rely on for recruitment and how they promote tissue repair in an MR1 independent manner. It also provides evidence to an Areg mediated mechanism supporting this repair function. These additional insights on MAIT cell biology could provide key therapeutic axes that could help alleviate the pain, discomfort and complications caused by unhealed or poorly healed wounds., Les dommages tissulaires d'origine mécanique, chimique ou infectieuse affectent toutes les barrières épithéliales, y compris la peau. La résolution rapide de ces dommages est essentielle pour que ces barrières recouvrent leur intégrité et fonction, elle implique l'action conjointe de cellules immunitaires infiltrant ces tissus. L'intérêt entourant l'étude des cellules MAIT (cellules T immunitaires associées aux muqueuse) dans la réparation provient de leur fréquence élevée dans la peau (jusqu'à 10% des cellules T) et de leur capacité à sécréter rapidement diverses molécules effectrices. Récemment, il a été démontré à la fois in vitro et in vivo que les cellules MAIT sont impliquées dans la cicatrisation des plaies. Cependant, les mécanismes qui sous-tendent cette fonction pro-réparatrice demeurent inconnus. En utilisant la souche congénique B6-MAITCAST (10 fois plus de cellules MAIT que les souris C57BL/6) et un modèle d'excision mimant le processus de réparation humain (Dunn et al., 2013), nous avons cherché à élucider ces mécanismes. Grâce à ces outils, nous montrons que les cellules MAIT accélèrent la fermeture des plaies. Ayant observé l’augmentation du nombre et de la fréquence des cellules MAIT au sein des plaies sans augmentation de leur prolifération, nous avons émis l'hypothèse qu’elles étaient recrutées. À l’aide de greffe de peau, nous avons mis en évidence que, contrairement aux cellules gdT résidentes, les cellules MAIT sont recrutées au site inflammatoire. La souris Kaedes (où la lumière ultraviolette induit un changement de fluorescence) et le traitement par FTY720 démontrent que les cellules recrutées transitent par les ganglions lymphatiques et ne migrent pas depuis d'autres endroits de la peau. Nous avons ensuite cherché à savoir si la signalisation du TCR, via MR1, la molécule de présentation de l'antigène des cellules MAIT, était nécessaire pour leur recrutement et fonction réparatrice. Pour étudier la dépendance des cellules MAIT à la signalisation TCR, nous avons réalisé une parabiose d'animaux MR1+ et MR1- et une greffe de peau MR1- sur des animaux MR1+, ceci a montré que leur recrutement était MR1 indépendant. Les expériences de blocage de CXCL16 et de suppression génétique de CXCR6 sur les cellules MAIT par CRISPR-Cas9 montrent que le recrutement est dépendant de la signalisation CXCL16-CXCR6. Nos expériences de transfert adoptif démontrent également que la fermeture de la plaie est indépendante de la signalisation du TCR.Concernant leur fonction effectrice, notre analyse scRNAseq suggère que le programme de réparation des cellules MAIT acquis dans la peau à l’état basal. De plus, nous observons qu’en présence des cellules MAIT il y a une augmentation significative de la longueur des langues épithéliales et de la prolifération au sein de ces langues. Ainsi, nous avons présupposé que les cellules MAIT pouvaient agir directement sur la croissance des kératinocytes. Cette théorie est appuyée par le scRNAseq montrant une augmentation de l’expression de signatures associées à des cellules pro-réparatrices produisant de l'amphireguline (Areg) par les cellules MAIT cutanées. Conjointement, nous observons la nécessité de l’Areg produite par les cellules PLZF dans notre modèle et l’augmentation de sa production par les cellules MAIT. Des expériences de transfert de cellules MAIT déficientes en Areg démontrent que l'Areg produite par les cellules MAIT est déterminante pour la réparation des plaies.Dans l'ensemble, notre étude décrit la dynamique des cellules MAIT dans la peau, les signaux sur lesquels elles s'appuient pour leur recrutement et la manière dont elles promeuvent la réparation des tissus. Elle fournit également des preuves d'un mécanisme médié par l'Areg sous-tendant cette fonction. Ces connaissances sur la biologie des cellules MAIT fournissent de nouveaux axes thérapeutiques qui pourraient atténuer la douleur, l'inconfort et les complications causés par les plaies non ou mal cicatrisées.
Published: 2022

12. Mechanisms Underlying Mait Cell Ability to Promote Skin Wound Repair

Author: Anastasia Du Halgouet, Aurélie Darbois, Mansour Alkobtawi, Martin Mestdagh, Aurélia Alphonse, Virginie Premel, Dietmar Zeiss, Yara El Morr, Hélène Bugaut, François Legoux, Laetitia Perrin, Selim Aractingi, Rachel Golub, Olivier Lantz, and Marion Salou
Subjects: History, Polymers and Plastics, Business and International Management, Industrial and Manufacturing Engineering
Published: 2022
Full Text: View/download PDF

13. Mechanisms Underlying Mait Cell Ability to Promote Skin Wound Repair

Author: Du Halgouet, Anastasia, primary, Darbois, Aurélie, additional, Alkobtawi, Mansour, additional, Mestdagh, Martin, additional, Alphonse, Aurélia, additional, Premel, Virginie, additional, Zeiss, Dietmar, additional, El Morr, Yara, additional, Bugaut, Hélène, additional, Legoux, François, additional, Perrin, Laetitia, additional, Aractingi, Selim, additional, Golub, Rachel, additional, Lantz, Olivier, additional, and Salou, Marion, additional
Published: 2022
Full Text: View/download PDF

14. Fasting Urinary Osmolality, CKD Progression, and Mortality: A Prospective Observational Study

Author: Jean-Philippe Haymann, Emmanuel Letavernier, Emmanuelle Vidal-Petiot, Martin Flamant, H. Fessi, Christian Jacquot, Jean-Jacques Boffa, Caroline du Halgouet, Pascal Houillier, Marion Vallet, Sandra Wagner, Gérard Maruani, Renaud de la Faille, François Vrtovsnik, Pierre Ronco, Eric Thervet, Eric Daugas, Marine Livrozet, Laurence Nicolet-Barousse, Marie Metzger, Bénédicte Stengel, Nahid Tabibzadeh, Alexandre Karras, Service d'Explorations fonctionnelles multidisciplinaires [CHU Tenon], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Tenon [APHP], Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), French-Clinical Research Infrastructure Network [Lyon] (FCRIN INI-CRCT - Coordination Nationale Réseau FORCE), Centre de Recherche en Nutrition Humaine Rhône-Alpes (CRNH-RH), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-CHU Saint-Etienne-Hospices Civils de Lyon (HCL)-CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Jean Monnet [Saint-Étienne] (UJM)-CHU Saint-Etienne-Hospices Civils de Lyon (HCL)-CHU Grenoble-Université Joseph Fourier - Grenoble 1 (UJF)-Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Service de Physiologie [Bichat-Claude Bernard], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Service de Physiologie [Georges-Pompidou], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Université Paris Descartes - Paris 5 (UPD5), Remodelage et Reparation du Tissu Renal, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunopathologie rénale, récepteurs et inflammation, Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Des Maladies Rénales Rares aux Maladies Fréquentes, Remodelage et Réparation, CHU Tenon [APHP], Service de Néphrologie et Dialyses [CHU Tenon], Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Service de Néphrologie et Hémodialyse [CHU HEGP], Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Université Paris Descartes - Paris 5 (UPD5)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, F-CRIN, INICRCT network, Paris, Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université de Paris (UP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), and NephroTest Study Group: Marine Livrozet, Emmanuel Letavernier, Pierre Ronco, Hafedh Fessi, Emmanuelle Vidal-Petiot, Eric Daugas, Caroline du Halgouet, Renaud de La Faille, Gerard Maruani, Marion Vallet, Laurence Nicolet-Barousse, Alexandre Karras, Christian Jacquot
Subjects: Male, urine concentration ability, 030232 urology & nephrology, Urine osmolality, urologic and male genital diseases, tubular damage, 0302 clinical medicine, Risk Factors, 030212 general & internal medicine, Prospective Studies, prognostic factor, ComputingMilieux_MISCELLANEOUS, Fasting, Middle Aged, Prognosis, female genital diseases and pregnancy complications, 3. Good health, Survival Rate, Nephrology, Disease Progression, Biomarker (medicine), biomarker, Female, France, medicine.symptom, glomerular filtration rate (GFR), Cohort study, Glomerular Filtration Rate, medicine.medical_specialty, Urinary system, CKD progression, Urology, chronic kidney disease (CKD), 03 medical and health sciences, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, Humans, Risk factor, Renal Insufficiency, Chronic, business.industry, Osmolar Concentration, medicine.disease, measured GFR (mGFR), Decreased glomerular filtration rate, end-stage renal disease (ESRD), Albuminuria, GFR decline, business, Biomarkers, Kidney disease
Abstract: International audience; Rationale & objective: Chronic kidney disease (CKD) characterized by decreased glomerular filtration rate (GFR) is often accompanied by various degrees of impaired tubular function in the cortex and medulla. Assessment of tubular function may therefore be useful in establishing the severity of kidney disease and identifying those at greater risk for CKD progression. We explored reductions in urinary concentrating ability, a well-known feature of CKD, as a risk factor for GFR decline and end-stage renal disease (ESRD).Study design: Prospective longitudinal cohort study.Setting & participants: 2,084 adult patients with CKD stages 1 to 4 from the French NephroTest Cohort Study.Predictor: Fasting urinary osmolality measured using delta cryoscopy.Outcomes: ESRD, mortality before ESRD, and measured GFR (mGFR) assessed using 51Cr-EDTA renal clearance.Analytical approach: Cause-specific hazards models were fit to estimate crude and adjusted associations of urinary osmolality with ESRD and death before ESRD. Linear mixed models with random intercepts were fit to evaluate the association of urinary osmolality with slope of decline in mGFR.Results: At baseline, mean age was 58.7±15.2 (SD) years with a median mGFR of 40.2 (IQR, 29.1-54.5) mL/min/1.73m2 and a median fasting urinary osmolality of 502.7±151.7mOsm/kg H2O. Baseline fasting urinary osmolality was strongly associated with mGFR (R=0.54; P < 0.001). 380 ESRD events and 225 deaths before ESRD occurred during a median follow-up of 5.9 (IQR, 3.8-8.2) years. Patients with lower baseline fasting urinary osmolality had higher adjusted risk for ESRD but not for mortality (HRs of 1.97 [95% CI, 1.26-3.08] and 0.99 [95% CI, 0.68-1.44], respectively, for the lowest vs highest tertile). Based on a mixed linear model adjusted for baseline mGFR and clinical characteristics, patients in the lowest tertile of baseline urinary osmolality had a steeper decline in kidney function (-4.9% ± 0.9% per year; P < 0.001) compared with patients in the highest tertile.Limitations: Fasting was self-reported.Conclusions: Fasting urinary osmolality may be a useful tool, in addition to GFR and albuminuria, for assessing nonglomerular damage in patients with CKD who are at higher risk for CKD progression.
Published: 2019
Full Text: View/download PDF

15. Longitudinal Bone Loss Occurs at the Radius in CKD

Author: Cailleaux, Pierre-Emmanuel, primary, Ostertag, Agnes, additional, Metzger, Marie, additional, Stengel, Bénédicte, additional, Boucquemont, Julie, additional, Houillier, Pascal, additional, Flamant, Martin, additional, Ureña-Torres, Pablo, additional, Cohen-Solal, Martine, additional, Letavernier, Emmanuel, additional, Ronco, Pierre, additional, Fessi, Hafedh, additional, Daugas, Eric, additional, du Halgouet, Caroline, additional, de La Faille, Renaud, additional, d’Auzac, Christian, additional, Maruani, Gerard, additional, Vallet, Marion, additional, Gauci, Cédric, additional, Haymann, Jean Philippe, additional, Thervet, Eric, additional, Boffa, Jean-Jacques, additional, Vrtovsnik, François, additional, Froissart, Marc, additional, Nicolet-Barousse, Laurence, additional, Roland, Mélanie, additional, and Jacquot, Christian, additional
Published: 2021
Full Text: View/download PDF

16. Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

Author: Cécile Couchoud, Florian Bayer, Carole Ayav, Clémence Béchade, Philippe Brunet, François Chantrel, Luc Frimat, Roula Galland, Maryvonne Hourmant, Emmanuelle Laurain, Thierry Lobbedez, Lucile Mercadal, Olivier Moranne, Abdelhamid Abbassi, Alain Debure, Abdallah Guerraoui, Abdelatif Benmoussa, Abdelaziz Hamani, Abdelaziz Ziane, Abdelhamid Nefti, Abdelkader Hadj, Abderrahim El Amari, Abderrahmane Ghazali, Abo Bakr Abd El Fatah Mohamed, Achour Laradi, Adel Ben Ahmed, Adel Sahar, Adele Pillet, Adeline Lacraz, Adnan Moinat, Afshin Massoumi, Agathe Pardon, Agnes Caillette Beaudoin, Agnes Chapelet Debout, Agnes Mariot, Ahmed Rachi, Aida Afiani, Aime Remy Boula, Al Jalaby, Alain Cremault, Alain Fournier, Alain Jeanson, Alain Lyon, Alain Nony, Alain Robert, Alain Slingeneyer, Alanor Agnes Labatide, Albane Brodin Sartorius, Albert Bensman, Albert Fournier, Alex Ranlin, Alex Vido Sandor, Alexandra Colombo, Alexandra Duhem, Alexandra Stancu, Alexandre Dufay, Alexandre Dumoulin, Alexandre Ebel, Alexandre Klein, Alexandre Martin, Alexandre Mouneimne, Alexandre Seidowsky, Alfio De Martin, Alfredo Zannier, Ali Aizel, Ali Hafi, Ali Zineddine Diddaoui, Alim Heyani, Alina Mocanu, Alina Preda, Aline Hafi, Aline Talaszka, Alyette Duquesne, Amar Amaouche, Amel Ghemmour, Amelie Simon, Amina Skalli, Amine Boukadida, Amr Ekhlas Ragab Eid, Ana Fedorca, Anabelle Baillet, Anais Poyet, Ancuta Bouffandeau Giorgita, Anderson Ratsimbazafy, Andre Pruna, Angel Argiles, Angelo Testa, Ann Karolien Vandooren, Anne Jolivot, Anne Kolko Labadens, Anne Lataste, Anne Maisin, Anne Paris, Anne Sechet, Anne Wuillai, Anne Elisabeth Heng, Anne Gaelle Josse, Anne Helene Querard, Anne Helene Reboux, Anne Laure Adra, Anne Laure Faller, Anne Laure Leclerc, Anne Laure Poitou, Annie Lahoche Manucci, Antoine Jacquet, Antoine Pommereau, Antoine Thierry, Arezki Adem, Arielle Chapelet, Arnaud Del Bello, Arnaud Delezire, Arnaud Garnier, Arnaud Guerard, Arnaud Klisnick, Arnaud Lionet, Arnaud Roccabianca, Arnaud Stolz, Arthur Capdeville, Asma Allal, Assem Alrifai, Assetou Diarrassouba, Assia Djema, Assia Ferhat Carre, Astrid Godron Dubrasquet, Atman Haddj Elmrabet, Audrey Jegado, Aurelia Bertholet Thomas, Aurelie Davourie Salandre, Aurelie Pajot, Aurelien Lorthioir, Aurelien Tiple, Aurore Sury, Ayman Abokasem, Ayman Sarraj, Bachir Henaoui, Baher Chaghouri, Bassem Wehbe, Beatrice Ball, Beatrice Viron, Belkassem Issad, Benedicte Hodemon Corne, Benedicte Janbon, Benjamin Deroure, Benjamin Savenkoff, Benoit Jonon, Benoit Vendrely, Benyakoub Djelaleddine, Bernard Ohry, Bernard Painchart, Bernard Strullu, Bernard Temperville, Bertin Ebikili, Bertrand Hacq, Bertrand Morel, Bilal Aoun, Blanca Muniz, Bouchra Chlih, Brahim Amara, Brice Mayor, Brigitte Gilson, Brigitte Llanas, Brigitte Zins, Bruno Bourgeon, Bruno Coevoet, Bruno Guery, Bruno Legallicier, Bruno Paris, Bruno Ranchin, Bruno Seigneuric, Camelia Ghiciuc Dita, Camelia Prelipcean, Carine Achard Hottelart, Carine Diet, Carlos Frangie, Carlos Vela, Carmina Muresan, Carole Deprele, Caroline Araujo, Caroline Bidault, Caroline Creput, Caroline Delclaux, Caroline Du Halgouet, Caroline Favennec, Caroline Freguin, Caroline Gourraud Vercel, Caroline Mesguen, Caroline Ndomo Obama, Caroline Poitou, Caroline Preissig Dirhold, Caroline Roubiou, Catherine Albert, Catherine Bessin, Catherine De Marion Gaja, Catherine Godart, Catherine Lasseur, Catherine Leocardi, Catherine Lumbroso, Catherine Melander, Catherine Michel, Catherine Quere Maurouard, Catherine Rouannet, Catherine Taddei, Cathy Verove, Cecile Guiraud, Cecile Tafelin, Cecile Turc Baron, Cedric Formet, Cedric Pinier, Celia Lessore De Ste Foy, Celine Granolleras, Chaouki Bennini, Charles Cartou, Charles Chazot, Charlotte Jouzel, Cherif Badid, Christa Roubicek, Christel Viaud, Christelle Verrier, Christian Chuet, Christian Combe, Christian Dabot, Christian Duvic, Christian Emond, Christian Lagarde, Christian Lamotte, Christian Pain, Christiane Mousson, Christie Lorriaux, Christine Beauchamp, Christine Fumeron, Christine Le Gurun, Christine Leroy, Christine Pietrement, Christine Richer, Christophe Bouaka, Christophe Charasse, Christophe Goupy, Christophe Ridel, Cindy Castrale, Cindy Detourne, Clair Francois, Claire Presne, Claire Trivin, Clarissa Von Kotze, Claude Bernard, Claude Bonniol, Claude Desvergnes, Claude Raharivelina, Claudia Nistor, Claudine Gueret, Claudine Lloret, Claudine Saltiel, Clelia Rosati, Clementine Rabate, Corina Stanescu, Corinne Ferrandini, Corinne Guibergia, Corinne Lemoine, Corinne Passeron, Cynthia Kahil, Cyril Garrouste, Cyril Vo Van, Cyrille Jolimoy, Dalila Kesraoui, Damien Jolly, Damien Thibaudin, Dan Teboulle, Daniel Daubresse, Daniel Louvet, Daniel Rasamimanantsoa, Daniel Toledano, Daniela Babici, Daniela David, Daniela Dincu, Danielle Bruno, Delia May, Delphine Haussaire, Delphine Henriet Viprey, Denis Bugnon, Denis Fouque, Denis Morin, Derradji Nour, Diab Mohamed Mahmoud, Diana Istrati Cristescu, Didier Aguilera, Didier Coste, Didier Hamel, Didier Le Chapois, Didier Testou, Dilaver Erbilgin, Djamal Dahmane, Doan Bui Quang, Dominique Bertrand, Dominique Besnier, Dominique Blanchier, Dominique Briffa, Dominique Caux, Dominique Durand, Dominique Fleury, Dominique Guerrot, Dominique Hestin, Dominique Jaubert, Dominique Joly, Dominique Lombart, Dominique Pagniez, Dominique Pierre, Dominique Schohn, Donatien Ikonga, Dorina Visanica, Dorothee Bazin, Edouard Boury, Edouard Maksour, Ekoue Agbonon, Elarbi Harrami, Elena Marcu, Elena Tudorache, Elisabeth Caniot, Elisabeth Semjen, Elisabeth Tomkiewicz, Elise Scheidt, Elke Gaboriau, Elodie Lamouroux, Elsa Guiard, Elsa Martin Passos, Emerson Nsembani, Emilie Fache, Emilie Kalbacher, Emilie Pambrun, Emilie Pincon, Emma Allain Launay, Emmanuel Baron, Emmanuel Dupuis, Emmanuel Villar, Emmanuelle Charlin, Emmanuelle Hecquet, Emmanuelle Kohler, Emmanuelle Rosier, Enrique Figueroa, Eric Azoulay, Eric Canivet, Eric Daugas, Eric Gauthier, Eric Laruelle, Eric Le Guen, Eric Legrand, Eric Moumas, Eric Postec, Eric Prinz, Eric Renaudineau, Estelle Desport, Estelle Ricard Sutra, Etienne Berard, Etienne Ged, Etienne Robin, Eve Vilaine, Evelyne Bargas, Evelyne Mac Namara, François Combarnous, Fatima Yazbeck, Fabien Gerard, Fabien Metivier, Fabien Parazols, Fabien Soulis, Fabrice Garnier, Fadhila Pech Messaoudene, Fadi Haidar, Fanny Boullenger, Fanny Lepeytre, Fanny Leroy, Fares Frejate, Farid Bellahsene, Farid Bellhasene, Farid Saidani, Fatouma Toure, Faycal Kriaa, Fazia Nemmar, Fernando Vetromile, Florence Chalmin, Florence Lucats, Florence Sens, Florence Villemain, Florent Plasse, Fouad Lebhour, Francis Schillinger, Franck Berge, Franck Bourdon, Franck Bridoux, Franck Reynaud, Francois Babinet, Francois Basse, Francois Chantrel, Francois Clair, Francois Coulomb, Francois De Cornelissen, Francois Glowacki, Francois Marchal, Francois Maurice, Francois Nobili, Francois Pourreau, Francois Provot, Francois Roux Amani, Francoise Broux, Francoise Bulte, Francoise Heibel, Francoise Leonetti, Francoise Moussion Schott, Frank Le Roy, Frederic Besson, Frederic Lavainne, Frederic Tollis, Frederique Bocquentin, Frederique Meeus, Frederique Vecina, Friederike Von Ey, Gabriel Balit, Gabriel Choukroun, Gabriel Gruget, Gabriel Huchard, Gabriella Golea, Gabrielle Duneau, Gaelle Lefrancois, Gaelle Pelle, Gaetan Lebrun, Genevieve Dumont, Georges Brillet, Georges Deschenes, Georges Mourad, Georges Stamatakis, Geraldine Cazajous, Geraldine D'ythurbide, Geraldine Robitaille Wiart, Gerard Cardon, Gerard Champion, Gerard Deschodt, Gerard Mangenot, Gerard Motte, Gerard Schortgen, Ghada Boulahia, Ghassan Maakaroun, Ghylene Bourdat Michel, Gilbert Zanetta, Gilles Hufnagel, Gilles Messier, Giorgina Piccoli, Gregoire Couvrat Desvergnes, Guillaume Bobrie, Guillaume Bonnard, Guillaume Clement, Guillaume Jean, Guillaume Queffeulou, Guillaume Seret, Guillaume Vernin, Guy Delavaud, Guy Lambrey, Guy Rostoker, Gwenaelle Poussard, Gwenaelle Roussey Kesler, H. Leon, Habib Aboubekr, Hacene Boulechfar, Hacene Sekhri, Hadia Hebibi, Hadjira Benalia, Hafed Fessi, Hafsabhai Atchia, Haiat Bittar, Hakim Maiza, Hakim Mazouz, Hamid El Ali, Hammouche Bougrida, Hans Van Der Pijl, Hassan Lokmane, Hassane Izzedine, Hassen Adda, Helene De Preneuf, Helene Leray, Helene Philippot, Henri Boulanger, Henri Merault, Henri Renaud, Herve Bonarek, Herve Maheut, Hilaire Nzeyimana, Hocine Mehama, Hocine Zaidi, Hugo Weclawiak, Hugues Flodrops, Huseyin Karaaslan, Ibrahim Haskour, Ihssen Belhadj, Imad Almoubarak, Imad Haddad, Ines Castellano, Ines Ferrandiz, Ioana Daniliuc, Ioana Darie, Ioana Enache, Ionut Prunescu, Irenee Djiconkpode, Irina Shahapuni, Isabelle Bouchoule, Isabelle Devriendt, Isabelle Kazes, Isabelle Kolb, Isabelle Landru, Isabelle Poli, Isabelle Rey, Isabelle Segalen, Isabelle Selcer, Isabelle Vernier, Isabelle Vrillon, Ismahane Guenifi, J. Dominique Gheerbrandt, Jacky Potier, Jacques Becart, Jacques Cledes, Jacques Ducros, Jacques Duvic, Jacques Fourcade, Jacques Gaultier, Jacques Jurine, Jacques Lebleu, Jacques Ollier, Jacques Ibsen Charles, Jamal Yazji, Janette Mansour, Jean Arnautou, Jean Brocard, Jean Carolfi, Jean Montoriol, Jean Baptiste Gouin, Jean Bernard Palcoux, Jean Christophe Bendini, Jean Claude Aldigier, Jean Claude Alphonse, Jean Daniel Delbet, Jean Francois Bonne, Jean Francois Cantin, Jean Francois De Fremont, Jean Francois Dessassis, Jean Francois Subra, Jean Francois Valentin, Jean Francois Verdier, Jean Jacques Dion, Jean Jacques Haultier, Jean Jacques Montseny, Jean Louis Bacri, Jean Louis Bouchet, Jean Luc Mahe, Jean Marc Chalopin, Jean Marc Gabriel, Jean Marc Hurot, Jean Marc Lanau, Jean Marie Batho, Jean Marie Coulibaly, Jean Michel Hardin, Jean Michel Marc, Jean Michel Poux, Jean Michel Rebibou, Jean Michel Tivollier, Jean Noel Ottavioli, Jean Paul Faucon, Jean Paul Imiela, Jean Paul Jaulin, Jean Paul Masselot, Jean Paul Ortiz, Jean Philippe Bourdenx, Jean Philippe Devaux, Jean Philippe Hammelin, Jean Pierre Rivory, Jean Pierre Wauquier, Jean Rene Larue, Jean Rene Mondain, Jean Sebastien Borde, Jean Simon Virot, Jean Yves Bosc, Jedjiga Achiche, Jennifer Parasote, Jeremie Diolez, Jerome Harambat, Jerome Potier, Jerome Sampol, Jihad Mustel, Jean Jacques Lefevre, Jocelyne Maurizi, Joel Gamberoni, Joelle Claudeon, Joelle Terzic, Joffrey Rogol, Johnny Sayegh, Jorge Cardozo, Jose Brasseur, Jose Guiserix, Joseph Barsumau, Julie Albaret, Julie Beaume, Julie Sohier Attias, Julien Dehay, Julien Hogan, Julien Journet, Julien Ott, Juliette Baleynaud, Justine Bacchetta, Justine Faucher, Kamel Yousfi, Karim Dardim, Karine Clabault, Karine Moreau, Kedna Thomas, Khaled Sirajedine, Khalil Chedid, Khalil El Kaeoui, Khalil El Karoui, Khedidja Bouachi, Kheira Hue, Khuzama El Nasser, Kodso Akposso, Kristian Kunz, Krzysztof Bijak, Lilia Kihal, L. Rasoloarijaona, Laid Harbouche, Larbi Bencheikh, Larbie Lamriben, Latifa Hanafi, Laura Braun Parvez, Laure Champion, Laure Croze, Laure Eprinchard, Laure Patrier, Laurence Nicolet, Laurence Vrigneaud, Laurent Duflot, Leandre Mackaya, Leila Chenine, Leon Odry, Lili Taghipour Tamiji, Lilia Antri Bouzar, Liliane Ngango Nga Messi, Lionel Le Mouellic, Lise Mandart, Lise Weis, Lise Marie Pouteau, Lora Georgieva, Lorita Vitanova, Lotfi Chalabi, Luc Delvallez, Luc Fromentin, Luc Marty, Luc Monjot, Luciana Spataru, Lucie Bessenay, Lucie Boissinot, Lucie Wajsbrot, Lucien Rakoff, Ludivine Lebourg, Lydie Perez, Lyliane Lafage, Lynda Azzouz, Madeleine Dumoulin, Messaoud Ouziala, Maan Joseph, Mabrouk Brahimi, Maeva Wong Fat, Magalie Fort, Magued Nakhla, Mahdi Abtahi, Mahen Albadawy, Mahmoud Alouach, Mahmoud Mezghani, Maite Daroux, Maklouf Boukelmoune, Malek Dhib, Malik Touam, Malina Dubau, Mamadou Balde, Man Nguyen Khoa, Manfred Ismer, Manolie Mehdi, Manon Laforet, Marc Bouiller, Marc Eugene, Marc Fila, Marc Hazzan, Marc Kribs, Marc Ladriere, Marc Lebot, Marc Padilla, Marc Souid, Marcel Marraoui, Maren Burbach, Maria Manescu, Maria Eugenia Noguera Gonzalez, Mariana Revenco, Marianne Terrasse, Marie Essi, Marie Alice Macher, Marie Beatrice Nogier, Marie Cecile Cazin, Marie Christine Schweitzer Camoin, Marie Christine Thouret, Marie Claude Hannaert, Marie France Servel, Marie Helene Chabannier, Marie Jeanne Coudert Krier, Marie Noelle Catoliquot, Marie Paule Guillodo, Marie Sophie Gavard, Marie Xaviere Vairon Codaccioni, Marina Rabec, Marine Freist, Marion Gauthier, Marion Lemaire, Marion Mehrenberger, Marion Venot, Marios Pongas, Marlene Beaubrun Diant, Martial Levannier, Martine Bertaux, Mathieu Jablonski, Mathieu Sacquepee, Mathilde Dargelos, Mathilde Lemoine, Mathilde Tamain, Matthieu Monge, Matthieu Reberolle, Maud Cousin, Maud Francois, Maurice Baron, Maxime Hoffmann, Maxime Ingwiller, Maxime Touzot, Mederick Mohajer, Mehadji Maaz, Melanie Hanoy, Melanie Marroc, Melodie Cuny, Menno Van Der Straaten, Mf. Serveaux, Michel Basteri, Michel Fen Chong, Michel Hecht, Michel Massad, Michel Normand, Michel Olmer, Michel Tolani, Michel Tsimaratos, Michele Hemery, Michele Kessler, Miguel Esposito, Milad Shenouda, Mimi Kareche, Mina Khalili, Mirella Diaconita, Mohamad Khair Rifard, Mohamed Aladib, Mohamed Belmouaz, Mohamed Brahim, Mohamed Diouani, Mohamed Fodil Cherif, Mohamed Jamali, Mohamed Maghlaoua, Mohamed Meddeb, Mohamed Ramdane, Mohamed Rifaat, Mohamed Sharifull Islam, Mohamed Adnan Abbade, Mokhtar Amrandi, Mokhtar Chawki, Monica Ciobotaru, Monica Indrieis, Monique Chanas, Monique Hoarau, Monzer Tomeh, Moufida Bellou, Mouloud Bouzernidj, Mounia Ammor, Mounir Guergour, Mountassir Benzakour, Mourad Hachicha, Moussa Coulibaly, Mustafa Smati, Mustapha Al Morabiti, Mustapha Amirou, Myriam Isnard, Myriam Pastural, Myriam Pujo, Nourredine Boumendjel, Nabil Majbri, Nabila Goumri, Nadege Mingat, Nader Bassilios, Nadia Kerkeni, Nadia Sedrati, Nadia Soltani, Nadine Maroun, Nadine Neyrat, Nahn Luang, Najeh El Esper, Naji Ammar, Nasredine Ghali, Nasser Hamdini, Natacha Noel, Natacha Potelune, Nathalie Maisonneuve, Nathalie Pertuiset, Nathalie Raynal, Nathalie Vittoz, Nazim Terki, Nelly Castin, Nestor Nankeu, Nicolas Bouvier, Nicolas Keller, Nicolas Legros, Nicolas Peters, Nicolas Quirin, Nicole Lefrancois, Nicole Monnier, Nicole Rance, Niels Bruckmann, Noel Mertens, Nolwenn Lorcy, Olivia Gilbert, Olivier Coldefy, Olivier Drouineau, Olivier Dunand, Olivier Fritz, Olivier Imhoff, Olivier Kourilsky, Olivier Lavelle, Olivier Papin, Olivier Roques, Ophelie Le Maner, Oussamah Fikri Benbrahim, Pablo Antonio Erina Torres, Pablo Antonio Urena Torres, Paolo Malvezzi, Pascal Bindi, Pascal Cluzel, Pascal Fontanier, Pascal Wheatley, Pascale Depraetre, Pascale Dubosq, Pascale Halin, Pascale Sebahoun, Pascale Siohan, Pascale Testevuide, Patrice Deteix, Patrice Nolen, Patricia Hue, Patricia Lemarchand, Patrick Donnadieu, Patrick Fievet, Patrick Fohrer, Patrick Francais, Patrick Giraud, Patrick Hallonet, Patrick Henri, Patrick Michaut, Patrick Niaudet, Patrick Pauly, Patrick Thomas, Patrik Deleaval, Paul Finielz, Paul Stroumza, Paule Hardy Yverneau, Pauline Caillard, Pedro Palacin, Perrine Aubertin, Philippe Attias, Philippe Chauveau, Philippe Coindre, Philippe Coste, Philippe Dubot, Philippe Fournier, Philippe Hiernaux, Philippe Jousset, Philippe Lan Yue Wah, Philippe Lang, Philippe Le Cacheux, Philippe Martin Dupont, Philippe Michel, Philippe Mirgaine, Philippe Moriniere, Philippe Nicoud, Philippe Rieu, Philippe Rousseau, Philippe Sporer, Philippe Thorel, Philippe Vanhille, Philippe Vigeral, Philippe Zaoui, Pierre Bataille, Pierre Brignon, Pierre Filipozzi, Pierre Housset, Pierre Peyronnet, Pierre Ramperez, Pierre Vautrin, Pierre Alexandre Michel, Pierre Francois Westeel, Pierre Louis Carron, Pierre Yves Durand, Pierrot Parent, Piotr Seniuta, François Kuentz, Rabah Fraoui, Rachel Tetaz, Rachid Amaria, Rachid Bourouma, Rachid Djeffal, Rachida Nebbad, Radia Allal, Radu Dimulescu, Rafaat Boustani, Rafik Mesbah, Raifat Makdassi, Raji Diab, Raluca Puslenghea, Raoul Roura, Rateb Khayat, Raymond Azar, Raymond Frayssinet, Regine Monkam, Rehouni Boulahrouz, Remi Boudet, Renato Demontis, Renaud Gansey, Rene Cuvelier, Renee Schmitt, Reschad Noordally, Reynald Binaut, Rezkallah Latif, Richard Dufresne, Richard Montagnac, Richard Reade, Robert Genin, Robert Novo, Rocsana Fickl, Roger Dufresne, Roger Magnol, Roland Issautier, Romain Mortelette, Ronan Delaval, Ronan Lohro, Roseline M'barga, S. Beau, Clémentine Dupuis, Marie Jacques Vidil, Sabria Hacini, Said Dahmoune, Saliha Lekhal, Salima Ahriz Sakso, Salima Saksi, Salvatore Citarda, Samir Boubenider, Samuel Kassis, Sandra Verhille, Sandrine Genestier, Sandrine Muller, Saoussen Krid, Sarah Richter, Sebastien Delbes, Sebastien Mailliez, Sebastien Veillon, Sébastien Nony, Seddick Benarbia, Severine Beaudreuil, Sidi Ali Benyaghla, Simon Duquennoy, Simona Baluta, Simona Boncila, Sonia Mzoughi, Sonia Ribal, Sophie Acamer, Sophie Chauvet, Sophie Girerd, Sophie Ozenne, Sophie Parahy, Sophie Rubens Duval, Sophie Taque, Soraya Menouer, Soumaya Chargui, Stanislas Bataille, Stephane Barbier, Stephane Billion, Stephane Roueff, Stephane Torner, Stephane Jean Martin, Stephanie Coupel, Sylvie Cloarec, Sylvie Lavaud, Sylvie Leou, T. Chatelet, Tania Onesta, Tassadit Benhabib, Tayeb Bensalem, Theodora Dimulescu, Theophile Sawadogo, Thibault Dolley Hitze, Thierry Baranger, Thierry Boudemaghe, Thierry Hannedouche, Thierry Krummel, Thierry Milcent, Thomas Dervaux, Thomas Guincestre, Thomas Kofman, Thomas Raphael, Thomas Sadreux, Tim Ulinski, Tiphaine Guyon Roger, Tomas Serrato, Tomek Kofman, Tony Wong, Toufik Boubia, Ubald Assogba Gbindoun, Usama Khuzaie, Valerie Caudwell, Valerie Chatelet, Valerie Crougneau, Valerie De Precigout, Valerie Drouillat, Valerie Galantine, Valerie Granveau Hugot, Valerie Leroy, Veronique Boubia, Veronique Falque, Veronique Fournier, Veronique Queron, Veronique Viviani, Victor Gueuttin, Victor Panescu, Victorio Menoyo Calonge, Viet Nguyen, Vincent Allot, Vincent Delattre, Vincent Leduc, Vincent Pradier, Violaine Emal Aglae, Viorica Badulescu, Virginia Molina, Virginie Besson, Virginie Chaigne, Waddah Jaber, Wael Boudi, Wael El Haggan, Wen Qin Guillon, Wided Tabbi Aneni, William Hanf, Wladimir Kohn, Xavier Bellenfant, Xavier Moreau Gaudry, Yahsou Delmas, Yannick Knefati, Yannick Saingra, Yannick Tirolien, Youssef Mann, Yvan Brunak, Yves Dimitrov, Yves Doussy, Yves Tanter, Zaid Benabid, Zaara Soltani, Zacharia Boukerroucha, Zafer Takla, Zana Ramanantsialonina, Zara Dickson, Zead Tubail, Zoe Koochaki Pour, Zohra Boukhalfa, Zohra Jacquot, Agence de la biomédecine [Saint-Denis la Plaine], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Université de Caen Normandie (UNICAEN), Normandie Université (NU), CALYDIAL Vienne, Partenaires INRAE, Centre hospitalier universitaire de Nantes (CHU Nantes), Hôpital Armand Trousseau [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre de néphrologie et transplantation rénale [Hôpital de la Conception - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)-Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Service d'Epidémiologie et Evaluations Cliniques [CHRU Nancy] (Pôle S2R), Centre Universitaire des Maladies Rénales [CHU Caen] (CUMR Caen), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Institut de Génomique Fonctionnelle (IGF), Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS), Groupe hospitalier de la région de Mulhouse Sud-Alsace (GHRMSA), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Aide à la Décision pour une Médecine Personnalisé - Laboratoire de Biostatistique, Epidémiologie et Recherche Clinique - EA 2415 (AIDMP), Université Montpellier 1 (UM1)-Université de Montpellier (UM), Assistance Publique - Hôpitaux de Marseille (APHM), Service de diabétologie [CHU Pitié-Salpétrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Université de Caen Normandie (UNICAEN), Service de Diabétologie [CHU Pitié-Salpétrière], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
Subjects: 0301 basic medicine, Male, medicine.medical_treatment, [SDV]Life Sciences [q-bio], 030232 urology & nephrology, Hemodialysis, Home, Disease, MESH: COVID-19 / therapy, registry, Ambulatory Care Facilities, [SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology, MESH: Aged, 80 and over, 0302 clinical medicine, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Risk Factors, 80 and over, Prevalence, covid, dialysis, epidemiology, mortality, Aged, Aged, 80 and over, COVID-19, Case-Control Studies, Critical Care, Female, France, Humans, Incidence, Middle Aged, Patient Acuity, Protective Factors, Registries, Renal Dialysis, SARS-CoV-2, Sex Factors, Hypoalbuminemia, MESH: France / epidemiology, education.field_of_study, Incidence (epidemiology), 3. Good health, MESH: COVID-19 / epidemiology, Nephrology, Hemodialysis, medicine.medical_specialty, Population, Lower risk, Article, 03 medical and health sciences, MESH: Sex Factors, Internal medicine, medicine, MESH: SARS-CoV-2, MESH: Renal Dialysis / statistics & numerical data, education, Dialysis, Vascular disease, business.industry, medicine.disease, Former Smoker, MESH: Critical Care / statistics & numerical data, 030104 developmental biology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, Home, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, MESH: Hemodialysis, Home / statistics & numerical data
Abstract: The aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study included all patients on dialysis recorded in the French REIN Registry in April 2020. Clinical characteristics at last follow-up and the evolution of COVID-19 illness severity over time were recorded for diagnosed cases (either suspicious clinical symptoms, characteristic signs on the chest scan or a positive reverse transcription polymerase chain reaction) for SARS-CoV-2. A total of 1,621 infected patients were reported on the REIN registry from March 16th, 2020 to May 4th, 2020. Of these, 344 died. The prevalence of COVID-19 patients varied from less than 1% to 10% between regions. The probability of being a case was higher in males, patients with diabetes, those in need of assistance for transfer or treated at a self-care unit. Dialysis at home was associated with a lower probability of being infected as was being a smoker, a former smoker, having an active malignancy, or peripheral vascular disease. Mortality in diagnosed cases (21%) was associated with the same causes as in the general population. Higher age, hypoalbuminemia and the presence of an ischemic heart disease were statistically independently associated with a higher risk of death. Being treated at a selfcare unit was associated with a lower risk. Thus, our study showed a relatively low frequency of COVID-19 among dialysis patients contrary to what might have been assumed., Graphical abstract
Published: 2020
Full Text: View/download PDF

17. A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

Author: Anne-Gaëlle Goubet, Jules Gilet, Emanuele Procopio, Aurélie Darbois, Wilfrid Richer, Celine Daviaud, Virginie Premel, Anastasia du Halgouet, Marion Salou, François Legoux, Ruby Alonso, Olivier Lantz, and Laurie Menger
Subjects: Male, 0301 basic medicine, Adoptive cell transfer, Parabiosis, Transgene, Immunology, chemical and pharmacologic phenomena, Mice, Transgenic, Spleen, Thymus Gland, Biology, Article, Transcriptome, Mice, 03 medical and health sciences, 0302 clinical medicine, RAR-related orphan receptor gamma, medicine, Animals, Humans, Immunology and Allergy, Lung, Research Articles, hemic and immune systems, Intercellular Adhesion Molecule-1, Natural killer T cell, Lymphocyte Function-Associated Antigen-1, 030104 developmental biology, medicine.anatomical_structure, Liver, Organ Specificity, Natural Killer T-Cells, Female, 030215 immunology
Abstract: Salou et al. wondered what could differentiate MAIT and NKT cells, if not for TCR specificity. Once split according to RORγt and T-bet–expressing subsets, MAIT and NKT share almost identical transcriptional programs acquired in the thymus, which result in specific tissue residency patterns., Mucosal-associated invariant T (MAIT) cells are abundant T cells with unique specificity for microbial metabolites. MAIT conservation along evolution indicates important functions, but their low frequency in mice has hampered their detailed characterization. Here, we performed the first transcriptomic analysis of murine MAIT cells. MAIT1 (RORγtneg) and MAIT17 (RORγt+) subsets were markedly distinct from mainstream T cells, but quasi-identical to NKT1 and NKT17 subsets. The expression of similar programs was further supported by strong correlations of MAIT and NKT frequencies in various organs. In both mice and humans, MAIT subsets expressed gene signatures associated with tissue residency. Accordingly, parabiosis experiments demonstrated that MAIT and NKT cells are resident in the spleen, liver, and lungs, with LFA1/ICAM1 interactions controlling MAIT1 and NKT1 retention in spleen and liver. The transcriptional program associated with tissue residency was already expressed in thymus, as confirmed by adoptive transfer experiments. Altogether, shared thymic differentiation processes generate “preset” NKT and MAIT subsets with defined effector functions, associated with specific positioning into tissues.
Published: 2018
Full Text: View/download PDF

18. Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

Author: Couchoud, Cécile, primary, Bayer, Florian, additional, Ayav, Carole, additional, Béchade, Clémence, additional, Brunet, Philippe, additional, Chantrel, François, additional, Frimat, Luc, additional, Galland, Roula, additional, Hourmant, Maryvonne, additional, Laurain, Emmanuelle, additional, Lobbedez, Thierry, additional, Mercadal, Lucile, additional, Moranne, Olivier, additional, Abbassi, Abdelhamid, additional, Debure, Alain, additional, Guerraoui, Abdallah, additional, Benmoussa, Abdelatif, additional, Hamani, Abdelaziz, additional, Ziane, Abdelaziz, additional, Nefti, Abdelhamid, additional, Hadj, Abdelkader, additional, El Amari, Abderrahim, additional, Ghazali, Abderrahmane, additional, Abd El Fatah Mohamed, Abo Bakr, additional, Laradi, Achour, additional, Ben Ahmed, Adel, additional, Sahar, Adel, additional, Pillet, Adele, additional, Lacraz, Adeline, additional, Moinat, Adnan, additional, Massoumi, Afshin, additional, Pardon, Agathe, additional, Beaudoin, Agnes Caillette, additional, Debout, Agnes Chapelet, additional, Mariot, Agnes, additional, Rachi, Ahmed, additional, Afiani, Aida, additional, Boula, Aime Remy, additional, Jalaby, Al, additional, Cremault, Alain, additional, Fournier, Alain, additional, Jeanson, Alain, additional, Lyon, Alain, additional, Nony, Alain, additional, Robert, Alain, additional, Slingeneyer, Alain, additional, Labatide, Alanor Agnes, additional, Sartorius, Albane Brodin, additional, Bensman, Albert, additional, Fournier, Albert, additional, Ranlin, Alex, additional, Sandor, Alex Vido, additional, Colombo, Alexandra, additional, Duhem, Alexandra, additional, Stancu, Alexandra, additional, Dufay, Alexandre, additional, Dumoulin, Alexandre, additional, Ebel, Alexandre, additional, Klein, Alexandre, additional, Martin, Alexandre, additional, Mouneimne, Alexandre, additional, Seidowsky, Alexandre, additional, De Martin, Alfio, additional, Zannier, Alfredo, additional, Aizel, Ali, additional, Hafi, Ali, additional, Diddaoui, Ali Zineddine, additional, Heyani, Alim, additional, Mocanu, Alina, additional, Preda, Alina, additional, Hafi, Aline, additional, Talaszka, Aline, additional, Duquesne, Alyette, additional, Amaouche, Amar, additional, Ghemmour, Amel, additional, Simon, Amelie, additional, Skalli, Amina, additional, Boukadida, Amine, additional, Ragab Eid, Amr Ekhlas, additional, Fedorca, Ana, additional, Baillet, Anabelle, additional, Poyet, Anais, additional, Giorgita, Ancuta Bouffandeau, additional, Ratsimbazafy, Anderson, additional, Pruna, Andre, additional, Argiles, Angel, additional, Testa, Angelo, additional, Vandooren, Ann Karolien, additional, Jolivot, Anne, additional, Labadens, Anne Kolko, additional, Lataste, Anne, additional, Maisin, Anne, additional, Paris, Anne, additional, Sechet, Anne, additional, Wuillai, Anne, additional, Heng, Anne Elisabeth, additional, Josse, Anne Gaelle, additional, Querard, Anne Helene, additional, Reboux, Anne Helene, additional, Adra, Anne Laure, additional, Faller, Anne Laure, additional, Leclerc, Anne Laure, additional, Poitou, Anne Laure, additional, Manucci, Annie Lahoche, additional, Jacquet, Antoine, additional, Pommereau, Antoine, additional, Thierry, Antoine, additional, Adem, Arezki, additional, Chapelet, Arielle, additional, Del Bello, Arnaud, additional, Delezire, Arnaud, additional, Garnier, Arnaud, additional, Guerard, Arnaud, additional, Klisnick, Arnaud, additional, Lionet, Arnaud, additional, Roccabianca, Arnaud, additional, Stolz, Arnaud, additional, Capdeville, Arthur, additional, Allal, Asma, additional, Alrifai, Assem, additional, Diarrassouba, Assetou, additional, Djema, Assia, additional, Carre, Assia Ferhat, additional, Dubrasquet, Astrid Godron, additional, Elmrabet, Atman Haddj, additional, Jegado, Audrey, additional, Thomas, Aurelia Bertholet, additional, Salandre, Aurelie Davourie, additional, Pajot, Aurelie, additional, Lorthioir, Aurelien, additional, Tiple, Aurelien, additional, Sury, Aurore, additional, Abokasem, Ayman, additional, Sarraj, Ayman, additional, Henaoui, Bachir, additional, Chaghouri, Baher, additional, Wehbe, Bassem, additional, Ball, Beatrice, additional, Viron, Beatrice, additional, Issad, Belkassem, additional, Corne, Benedicte Hodemon, additional, Janbon, Benedicte, additional, Deroure, Benjamin, additional, Savenkoff, Benjamin, additional, Jonon, Benoit, additional, Vendrely, Benoit, additional, Djelaleddine, Benyakoub, additional, Ohry, Bernard, additional, Painchart, Bernard, additional, Strullu, Bernard, additional, Temperville, Bernard, additional, Ebikili, Bertin, additional, Hacq, Bertrand, additional, Morel, Bertrand, additional, Aoun, Bilal, additional, Muniz, Blanca, additional, Chlih, Bouchra, additional, Amara, Brahim, additional, Mayor, Brice, additional, Gilson, Brigitte, additional, Llanas, Brigitte, additional, Zins, Brigitte, additional, Bourgeon, Bruno, additional, Coevoet, Bruno, additional, Guery, Bruno, additional, Legallicier, Bruno, additional, Paris, Bruno, additional, Ranchin, Bruno, additional, Seigneuric, Bruno, additional, Dita, Camelia Ghiciuc, additional, Prelipcean, Camelia, additional, Hottelart, Carine Achard, additional, Diet, Carine, additional, Frangie, Carlos, additional, Vela, Carlos, additional, Muresan, Carmina, additional, Deprele, Carole, additional, Araujo, Caroline, additional, Bidault, Caroline, additional, Creput, Caroline, additional, Delclaux, Caroline, additional, Du Halgouet, Caroline, additional, Favennec, Caroline, additional, Freguin, Caroline, additional, Vercel, Caroline Gourraud, additional, Mesguen, Caroline, additional, Obama, Caroline Ndomo, additional, Poitou, Caroline, additional, Dirhold, Caroline Preissig, additional, Roubiou, Caroline, additional, Albert, Catherine, additional, Bessin, Catherine, additional, De Marion Gaja, Catherine, additional, Godart, Catherine, additional, Lasseur, Catherine, additional, Leocardi, Catherine, additional, Lumbroso, Catherine, additional, Melander, Catherine, additional, Michel, Catherine, additional, Maurouard, Catherine Quere, additional, Rouannet, Catherine, additional, Taddei, Catherine, additional, Verove, Cathy, additional, Guiraud, Cecile, additional, Tafelin, Cecile, additional, Baron, Cecile Turc, additional, Formet, Cedric, additional, Pinier, Cedric, additional, De Ste Foy, Celia Lessore, additional, Granolleras, Celine, additional, Bennini, Chaouki, additional, Cartou, Charles, additional, Chazot, Charles, additional, Jouzel, Charlotte, additional, Badid, Cherif, additional, Roubicek, Christa, additional, Viaud, Christel, additional, Verrier, Christelle, additional, Chuet, Christian, additional, Combe, Christian, additional, Dabot, Christian, additional, Duvic, Christian, additional, Emond, Christian, additional, Lagarde, Christian, additional, Lamotte, Christian, additional, Pain, Christian, additional, Mousson, Christiane, additional, Lorriaux, Christie, additional, Beauchamp, Christine, additional, Fumeron, Christine, additional, Le Gurun, Christine, additional, Leroy, Christine, additional, Pietrement, Christine, additional, Richer, Christine, additional, Bouaka, Christophe, additional, Charasse, Christophe, additional, Goupy, Christophe, additional, Ridel, Christophe, additional, Castrale, Cindy, additional, Detourne, Cindy, additional, Francois, Clair, additional, Presne, Claire, additional, Trivin, Claire, additional, Von Kotze, Clarissa, additional, Bernard, Claude, additional, Bonniol, Claude, additional, Desvergnes, Claude, additional, Raharivelina, Claude, additional, Nistor, Claudia, additional, Gueret, Claudine, additional, Lloret, Claudine, additional, Saltiel, Claudine, additional, Rosati, Clelia, additional, Rabate, Clementine, additional, Stanescu, Corina, additional, Ferrandini, Corinne, additional, Guibergia, Corinne, additional, Lemoine, Corinne, additional, Passeron, Corinne, additional, Kahil, Cynthia, additional, Garrouste, Cyril, additional, Van, Cyril Vo, additional, Jolimoy, Cyrille, additional, Kesraoui, Dalila, additional, Jolly, Damien, additional, Thibaudin, Damien, additional, Teboulle, Dan, additional, Daubresse, Daniel, additional, Louvet, Daniel, additional, Rasamimanantsoa, Daniel, additional, Toledano, Daniel, additional, Babici, Daniela, additional, David, Daniela, additional, Dincu, Daniela, additional, Bruno, Danielle, additional, May, Delia, additional, Haussaire, Delphine, additional, Viprey, Delphine Henriet, additional, Bugnon, Denis, additional, Fouque, Denis, additional, Morin, Denis, additional, Nour, Derradji, additional, Mahmoud, Diab Mohamed, additional, Cristescu, Diana Istrati, additional, Aguilera, Didier, additional, Coste, Didier, additional, Hamel, Didier, additional, Le Chapois, Didier, additional, Testou, Didier, additional, Erbilgin, Dilaver, additional, Dahmane, Djamal, additional, Quang, Doan Bui, additional, Bertrand, Dominique, additional, Besnier, Dominique, additional, Blanchier, Dominique, additional, Briffa, Dominique, additional, Caux, Dominique, additional, Durand, Dominique, additional, Fleury, Dominique, additional, Guerrot, Dominique, additional, Hestin, Dominique, additional, Jaubert, Dominique, additional, Joly, Dominique, additional, Lombart, Dominique, additional, Pagniez, Dominique, additional, Pierre, Dominique, additional, Schohn, Dominique, additional, Ikonga, Donatien, additional, Visanica, Dorina, additional, Bazin, Dorothee, additional, Boury, Edouard, additional, Maksour, Edouard, additional, Agbonon, Ekoue, additional, Harrami, Elarbi, additional, Marcu, Elena, additional, Tudorache, Elena, additional, Caniot, Elisabeth, additional, Semjen, Elisabeth, additional, Tomkiewicz, Elisabeth, additional, Scheidt, Elise, additional, Gaboriau, Elke, additional, Lamouroux, Elodie, additional, Guiard, Elsa, additional, Passos, Elsa Martin, additional, Nsembani, Emerson, additional, Fache, Emilie, additional, Kalbacher, Emilie, additional, Pambrun, Emilie, additional, Pincon, Emilie, additional, Launay, Emma Allain, additional, Baron, Emmanuel, additional, Dupuis, Emmanuel, additional, Villar, Emmanuel, additional, Charlin, Emmanuelle, additional, Hecquet, Emmanuelle, additional, Kohler, Emmanuelle, additional, Rosier, Emmanuelle, additional, Figueroa, Enrique, additional, Azoulay, Eric, additional, Canivet, Eric, additional, Daugas, Eric, additional, Gauthier, Eric, additional, Laruelle, Eric, additional, Le Guen, Eric, additional, Legrand, Eric, additional, Moumas, Eric, additional, Postec, Eric, additional, Prinz, Eric, additional, Renaudineau, Eric, additional, Desport, Estelle, additional, Sutra, Estelle Ricard, additional, Berard, Etienne, additional, Ged, Etienne, additional, Robin, Etienne, additional, Vilaine, Eve, additional, Bargas, Evelyne, additional, Namara, Evelyne Mac, additional, Combarnous, François, additional, Yazbeck, Fatima, additional, Gerard, Fabien, additional, Metivier, Fabien, additional, Parazols, Fabien, additional, Soulis, Fabien, additional, Garnier, Fabrice, additional, Messaoudene, Fadhila Pech, additional, Haidar, Fadi, additional, Boullenger, Fanny, additional, Lepeytre, Fanny, additional, Leroy, Fanny, additional, Frejate, Fares, additional, Bellahsene, Farid, additional, Bellhasene, Farid, additional, Saidani, Farid, additional, Toure, Fatouma, additional, Kriaa, Faycal, additional, Nemmar, Fazia, additional, Vetromile, Fernando, additional, Chalmin, Florence, additional, Lucats, Florence, additional, Sens, Florence, additional, Villemain, Florence, additional, Plasse, Florent, additional, Lebhour, Fouad, additional, Schillinger, Francis, additional, Berge, Franck, additional, Bourdon, Franck, additional, Bridoux, Franck, additional, Reynaud, Franck, additional, Babinet, Francois, additional, Basse, Francois, additional, Chantrel, Francois, additional, Clair, Francois, additional, Coulomb, Francois, additional, De Cornelissen, Francois, additional, Glowacki, Francois, additional, Marchal, Francois, additional, Maurice, Francois, additional, Nobili, Francois, additional, Pourreau, Francois, additional, Provot, Francois, additional, Amani, Francois Roux, additional, Broux, Francoise, additional, Bulte, Francoise, additional, Heibel, Francoise, additional, Leonetti, Francoise, additional, Schott, Francoise Moussion, additional, Le Roy, Frank, additional, Besson, Frederic, additional, Lavainne, Frederic, additional, Tollis, Frederic, additional, Bocquentin, Frederique, additional, Meeus, Frederique, additional, Vecina, Frederique, additional, Von Ey, Friederike, additional, Balit, Gabriel, additional, Choukroun, Gabriel, additional, Gruget, Gabriel, additional, Huchard, Gabriel, additional, Golea, Gabriella, additional, Duneau, Gabrielle, additional, Lefrancois, Gaelle, additional, Pelle, Gaelle, additional, Lebrun, Gaetan, additional, Dumont, Genevieve, additional, Brillet, Georges, additional, Deschenes, Georges, additional, Mourad, Georges, additional, Stamatakis, Georges, additional, Cazajous, Geraldine, additional, D'ythurbide, Geraldine, additional, Wiart, Geraldine Robitaille, additional, Cardon, Gerard, additional, Champion, Gerard, additional, Deschodt, Gerard, additional, Mangenot, Gerard, additional, Motte, Gerard, additional, Schortgen, Gerard, additional, Boulahia, Ghada, additional, Maakaroun, Ghassan, additional, Michel, Ghylene Bourdat, additional, Zanetta, Gilbert, additional, Hufnagel, Gilles, additional, Messier, Gilles, additional, Piccoli, Giorgina, additional, Desvergnes, Gregoire Couvrat, additional, Bobrie, Guillaume, additional, Bonnard, Guillaume, additional, Clement, Guillaume, additional, Jean, Guillaume, additional, Queffeulou, Guillaume, additional, Seret, Guillaume, additional, Vernin, Guillaume, additional, Delavaud, Guy, additional, Lambrey, Guy, additional, Rostoker, Guy, additional, Poussard, Gwenaelle, additional, Kesler, Gwenaelle Roussey, additional, Leon, H., additional, Aboubekr, Habib, additional, Boulechfar, Hacene, additional, Sekhri, Hacene, additional, Hebibi, Hadia, additional, Benalia, Hadjira, additional, Fessi, Hafed, additional, Atchia, Hafsabhai, additional, Bittar, Haiat, additional, Maiza, Hakim, additional, Mazouz, Hakim, additional, El Ali, Hamid, additional, Bougrida, Hammouche, additional, Van Der Pijl, Hans, additional, Lokmane, Hassan, additional, Izzedine, Hassane, additional, Adda, Hassen, additional, De Preneuf, Helene, additional, Leray, Helene, additional, Philippot, Helene, additional, Boulanger, Henri, additional, Merault, Henri, additional, Renaud, Henri, additional, Bonarek, Herve, additional, Maheut, Herve, additional, Nzeyimana, Hilaire, additional, Mehama, Hocine, additional, Zaidi, Hocine, additional, Weclawiak, Hugo, additional, Flodrops, Hugues, additional, Karaaslan, Huseyin, additional, Haskour, Ibrahim, additional, Belhadj, Ihssen, additional, Almoubarak, Imad, additional, Haddad, Imad, additional, Castellano, Ines, additional, Ferrandiz, Ines, additional, Daniliuc, Ioana, additional, Darie, Ioana, additional, Enache, Ioana, additional, Prunescu, Ionut, additional, Djiconkpode, Irenee, additional, Shahapuni, Irina, additional, Bouchoule, Isabelle, additional, Devriendt, Isabelle, additional, Kazes, Isabelle, additional, Kolb, Isabelle, additional, Landru, Isabelle, additional, Poli, Isabelle, additional, Rey, Isabelle, additional, Segalen, Isabelle, additional, Selcer, Isabelle, additional, Vernier, Isabelle, additional, Vrillon, Isabelle, additional, Guenifi, Ismahane, additional, Gheerbrandt, J. Dominique, additional, Potier, Jacky, additional, Becart, Jacques, additional, Cledes, Jacques, additional, Ducros, Jacques, additional, Duvic, Jacques, additional, Fourcade, Jacques, additional, Gaultier, Jacques, additional, Jurine, Jacques, additional, Lebleu, Jacques, additional, Ollier, Jacques, additional, Charles, Jacques Ibsen, additional, Yazji, Jamal, additional, Mansour, Janette, additional, Arnautou, Jean, additional, Brocard, Jean, additional, Carolfi, Jean, additional, Montoriol, Jean, additional, Gouin, Jean Baptiste, additional, Palcoux, Jean Bernard, additional, Bendini, Jean Christophe, additional, Aldigier, Jean Claude, additional, Alphonse, Jean Claude, additional, Delbet, Jean Daniel, additional, Bonne, Jean Francois, additional, Cantin, Jean Francois, additional, De Fremont, Jean Francois, additional, Dessassis, Jean Francois, additional, Subra, Jean Francois, additional, Valentin, Jean Francois, additional, Verdier, Jean Francois, additional, Dion, Jean Jacques, additional, Haultier, Jean Jacques, additional, Montseny, Jean Jacques, additional, Bacri, Jean Louis, additional, Bouchet, Jean Louis, additional, Mahe, Jean Luc, additional, Chalopin, Jean Marc, additional, Gabriel, Jean Marc, additional, Hurot, Jean Marc, additional, Lanau, Jean Marc, additional, Batho, Jean Marie, additional, Coulibaly, Jean Marie, additional, Hardin, Jean Michel, additional, Marc, Jean Michel, additional, Poux, Jean Michel, additional, Rebibou, Jean Michel, additional, Tivollier, Jean Michel, additional, Ottavioli, Jean Noel, additional, Faucon, Jean Paul, additional, Imiela, Jean Paul, additional, Jaulin, Jean Paul, additional, Masselot, Jean Paul, additional, Ortiz, Jean Paul, additional, Bourdenx, Jean Philippe, additional, Devaux, Jean Philippe, additional, Hammelin, Jean Philippe, additional, Rivory, Jean Pierre, additional, Wauquier, Jean Pierre, additional, Larue, Jean Rene, additional, Mondain, Jean Rene, additional, Borde, Jean Sebastien, additional, Virot, Jean Simon, additional, Bosc, Jean Yves, additional, Achiche, Jedjiga, additional, Parasote, Jennifer, additional, Diolez, Jeremie, additional, Harambat, Jerome, additional, Potier, Jerome, additional, Sampol, Jerome, additional, Mustel, Jihad, additional, Lefevre, Jean Jacques, additional, Maurizi, Jocelyne, additional, Gamberoni, Joel, additional, Claudeon, Joelle, additional, Terzic, Joelle, additional, Rogol, Joffrey, additional, Sayegh, Johnny, additional, Cardozo, Jorge, additional, Brasseur, Jose, additional, Guiserix, Jose, additional, Barsumau, Joseph, additional, Albaret, Julie, additional, Beaume, Julie, additional, Attias, Julie Sohier, additional, Dehay, Julien, additional, Hogan, Julien, additional, Journet, Julien, additional, Ott, Julien, additional, Baleynaud, Juliette, additional, Bacchetta, Justine, additional, Faucher, Justine, additional, Yousfi, Kamel, additional, Dardim, Karim, additional, Clabault, Karine, additional, Moreau, Karine, additional, Thomas, Kedna, additional, Sirajedine, Khaled, additional, Chedid, Khalil, additional, El Kaeoui, Khalil, additional, El Karoui, Khalil, additional, Bouachi, Khedidja, additional, Hue, Kheira, additional, El Nasser, Khuzama, additional, Akposso, Kodso, additional, Kunz, Kristian, additional, Bijak, Krzysztof, additional, Kihal, Lilia, additional, Rasoloarijaona, L., additional, Harbouche, Laid, additional, Bencheikh, Larbi, additional, Lamriben, Larbie, additional, Hanafi, Latifa, additional, Parvez, Laura Braun, additional, Champion, Laure, additional, Croze, Laure, additional, Eprinchard, Laure, additional, Patrier, Laure, additional, Nicolet, Laurence, additional, Vrigneaud, Laurence, additional, Duflot, Laurent, additional, Mackaya, Leandre, additional, Chenine, Leila, additional, Odry, Leon, additional, Tamiji, Lili Taghipour, additional, Bouzar, Lilia Antri, additional, Nga Messi, Liliane Ngango, additional, Le Mouellic, Lionel, additional, Mandart, Lise, additional, Weis, Lise, additional, Pouteau, Lise Marie, additional, Georgieva, Lora, additional, Vitanova, Lorita, additional, Chalabi, Lotfi, additional, Delvallez, Luc, additional, Fromentin, Luc, additional, Marty, Luc, additional, Monjot, Luc, additional, Spataru, Luciana, additional, Bessenay, Lucie, additional, Boissinot, Lucie, additional, Wajsbrot, Lucie, additional, Rakoff, Lucien, additional, Lebourg, Ludivine, additional, Perez, Lydie, additional, Lafage, Lyliane, additional, Azzouz, Lynda, additional, Dumoulin, Madeleine, additional, Ouziala, Messaoud, additional, Joseph, Maan, additional, Brahimi, Mabrouk, additional, Fat, Maeva Wong, additional, Fort, Magalie, additional, Nakhla, Magued, additional, Abtahi, Mahdi, additional, Albadawy, Mahen, additional, Alouach, Mahmoud, additional, Mezghani, Mahmoud, additional, Daroux, Maite, additional, Boukelmoune, Maklouf, additional, Dhib, Malek, additional, Touam, Malik, additional, Dubau, Malina, additional, Balde, Mamadou, additional, Khoa, Man Nguyen, additional, Ismer, Manfred, additional, Mehdi, Manolie, additional, Laforet, Manon, additional, Bouiller, Marc, additional, Eugene, Marc, additional, Fila, Marc, additional, Hazzan, Marc, additional, Kribs, Marc, additional, Ladriere, Marc, additional, Lebot, Marc, additional, Padilla, Marc, additional, Souid, Marc, additional, Marraoui, Marcel, additional, Burbach, Maren, additional, Manescu, Maria, additional, Noguera Gonzalez, Maria Eugenia, additional, Revenco, Mariana, additional, Terrasse, Marianne, additional, Essi, Marie, additional, Macher, Marie Alice, additional, Nogier, Marie Beatrice, additional, Cazin, Marie Cecile, additional, Schweitzer Camoin, Marie Christine, additional, Thouret, Marie Christine, additional, Hannaert, Marie Claude, additional, Servel, Marie France, additional, Chabannier, Marie Helene, additional, Coudert Krier, Marie Jeanne, additional, Catoliquot, Marie Noelle, additional, Guillodo, Marie Paule, additional, Gavard, Marie Sophie, additional, Vairon Codaccioni, Marie Xaviere, additional, Rabec, Marina, additional, Freist, Marine, additional, Gauthier, Marion, additional, Lemaire, Marion, additional, Mehrenberger, Marion, additional, Venot, Marion, additional, Pongas, Marios, additional, Diant, Marlene Beaubrun, additional, Levannier, Martial, additional, Bertaux, Martine, additional, Jablonski, Mathieu, additional, Sacquepee, Mathieu, additional, Dargelos, Mathilde, additional, Lemoine, Mathilde, additional, Tamain, Mathilde, additional, Monge, Matthieu, additional, Reberolle, Matthieu, additional, Cousin, Maud, additional, Francois, Maud, additional, Baron, Maurice, additional, Hoffmann, Maxime, additional, Ingwiller, Maxime, additional, Touzot, Maxime, additional, Mohajer, Mederick, additional, Maaz, Mehadji, additional, Hanoy, Melanie, additional, Marroc, Melanie, additional, Cuny, Melodie, additional, Van Der Straaten, Menno, additional, Serveaux, Mf., additional, Basteri, Michel, additional, Chong, Michel Fen, additional, Hecht, Michel, additional, Massad, Michel, additional, Normand, Michel, additional, Olmer, Michel, additional, Tolani, Michel, additional, Tsimaratos, Michel, additional, Hemery, Michele, additional, Kessler, Michele, additional, Esposito, Miguel, additional, Shenouda, Milad, additional, Kareche, Mimi, additional, Khalili, Mina, additional, Diaconita, Mirella, additional, Rifard, Mohamad Khair, additional, Aladib, Mohamed, additional, Belmouaz, Mohamed, additional, Brahim, Mohamed, additional, Diouani, Mohamed, additional, Cherif, Mohamed Fodil, additional, Jamali, Mohamed, additional, Maghlaoua, Mohamed, additional, Meddeb, Mohamed, additional, Ramdane, Mohamed, additional, Rifaat, Mohamed, additional, Islam, Mohamed Sharifull, additional, Abbade, Mohamed Adnan, additional, Amrandi, Mokhtar, additional, Chawki, Mokhtar, additional, Ciobotaru, Monica, additional, Indrieis, Monica, additional, Chanas, Monique, additional, Hoarau, Monique, additional, Tomeh, Monzer, additional, Bellou, Moufida, additional, Bouzernidj, Mouloud, additional, Ammor, Mounia, additional, Guergour, Mounir, additional, Benzakour, Mountassir, additional, Hachicha, Mourad, additional, Coulibaly, Moussa, additional, Smati, Mustafa, additional, Al Morabiti, Mustapha, additional, Amirou, Mustapha, additional, Isnard, Myriam, additional, Pastural, Myriam, additional, Pujo, Myriam, additional, Boumendjel, Nourredine, additional, Majbri, Nabil, additional, Goumri, Nabila, additional, Mingat, Nadege, additional, Bassilios, Nader, additional, Kerkeni, Nadia, additional, Sedrati, Nadia, additional, Soltani, Nadia, additional, Maroun, Nadine, additional, Neyrat, Nadine, additional, Luang, Nahn, additional, El Esper, Najeh, additional, Ammar, Naji, additional, Ghali, Nasredine, additional, Hamdini, Nasser, additional, Noel, Natacha, additional, Potelune, Natacha, additional, Maisonneuve, Nathalie, additional, Pertuiset, Nathalie, additional, Raynal, Nathalie, additional, Vittoz, Nathalie, additional, Terki, Nazim, additional, Castin, Nelly, additional, Nankeu, Nestor, additional, Bouvier, Nicolas, additional, Keller, Nicolas, additional, Legros, Nicolas, additional, Peters, Nicolas, additional, Quirin, Nicolas, additional, Lefrancois, Nicole, additional, Monnier, Nicole, additional, Rance, Nicole, additional, Bruckmann, Niels, additional, Mertens, Noel, additional, Lorcy, Nolwenn, additional, Gilbert, Olivia, additional, Coldefy, Olivier, additional, Drouineau, Olivier, additional, Dunand, Olivier, additional, Fritz, Olivier, additional, Imhoff, Olivier, additional, Kourilsky, Olivier, additional, Lavelle, Olivier, additional, Papin, Olivier, additional, Roques, Olivier, additional, Le Maner, Ophelie, additional, Benbrahim, Oussamah Fikri, additional, Erina Torres, Pablo Antonio, additional, Urena Torres, Pablo Antonio, additional, Malvezzi, Paolo, additional, Bindi, Pascal, additional, Cluzel, Pascal, additional, Fontanier, Pascal, additional, Wheatley, Pascal, additional, Depraetre, Pascale, additional, Dubosq, Pascale, additional, Halin, Pascale, additional, Sebahoun, Pascale, additional, Siohan, Pascale, additional, Testevuide, Pascale, additional, Deteix, Patrice, additional, Nolen, Patrice, additional, Hue, Patricia, additional, Lemarchand, Patricia, additional, Donnadieu, Patrick, additional, Fievet, Patrick, additional, Fohrer, Patrick, additional, Francais, Patrick, additional, Giraud, Patrick, additional, Hallonet, Patrick, additional, Henri, Patrick, additional, Michaut, Patrick, additional, Niaudet, Patrick, additional, Pauly, Patrick, additional, Thomas, Patrick, additional, Deleaval, Patrik, additional, Finielz, Paul, additional, Stroumza, Paul, additional, Yverneau, Paule Hardy, additional, Caillard, Pauline, additional, Palacin, Pedro, additional, Aubertin, Perrine, additional, Attias, Philippe, additional, Chauveau, Philippe, additional, Coindre, Philippe, additional, Coste, Philippe, additional, Dubot, Philippe, additional, Fournier, Philippe, additional, Hiernaux, Philippe, additional, Jousset, Philippe, additional, Yue Wah, Philippe Lan, additional, Lang, Philippe, additional, Le Cacheux, Philippe, additional, Dupont, Philippe Martin, additional, Michel, Philippe, additional, Mirgaine, Philippe, additional, Moriniere, Philippe, additional, Nicoud, Philippe, additional, Rieu, Philippe, additional, Rousseau, Philippe, additional, Sporer, Philippe, additional, Thorel, Philippe, additional, Vanhille, Philippe, additional, Vigeral, Philippe, additional, Zaoui, Philippe, additional, Bataille, Pierre, additional, Brignon, Pierre, additional, Filipozzi, Pierre, additional, Housset, Pierre, additional, Peyronnet, Pierre, additional, Ramperez, Pierre, additional, Vautrin, Pierre, additional, Michel, Pierre Alexandre, additional, Westeel, Pierre Francois, additional, Carron, Pierre Louis, additional, Durand, Pierre Yves, additional, Parent, Pierrot, additional, Seniuta, Piotr, additional, Kuentz, François, additional, Fraoui, Rabah, additional, Tetaz, Rachel, additional, Amaria, Rachid, additional, Bourouma, Rachid, additional, Djeffal, Rachid, additional, Nebbad, Rachida, additional, Allal, Radia, additional, Dimulescu, Radu, additional, Boustani, Rafaat, additional, Mesbah, Rafik, additional, Makdassi, Raifat, additional, Diab, Raji, additional, Puslenghea, Raluca, additional, Roura, Raoul, additional, Khayat, Rateb, additional, Azar, Raymond, additional, Frayssinet, Raymond, additional, Monkam, Regine, additional, Boulahrouz, Rehouni, additional, Boudet, Remi, additional, Demontis, Renato, additional, Gansey, Renaud, additional, Cuvelier, Rene, additional, Schmitt, Renee, additional, Noordally, Reschad, additional, Binaut, Reynald, additional, Latif, Rezkallah, additional, Dufresne, Richard, additional, Montagnac, Richard, additional, Reade, Richard, additional, Genin, Robert, additional, Novo, Robert, additional, Fickl, Rocsana, additional, Dufresne, Roger, additional, Magnol, Roger, additional, Issautier, Roland, additional, Mortelette, Romain, additional, Delaval, Ronan, additional, Lohro, Ronan, additional, M'barga, Roseline, additional, Beau, S., additional, Dupuis, Clémentine, additional, Vidil, Marie Jacques, additional, Hacini, Sabria, additional, Dahmoune, Said, additional, Lekhal, Saliha, additional, Sakso, Salima Ahriz, additional, Saksi, Salima, additional, Citarda, Salvatore, additional, Boubenider, Samir, additional, Kassis, Samuel, additional, Verhille, Sandra, additional, Genestier, Sandrine, additional, Muller, Sandrine, additional, Krid, Saoussen, additional, Richter, Sarah, additional, Delbes, Sebastien, additional, Mailliez, Sebastien, additional, Veillon, Sebastien, additional, Nony, Sébastien, additional, Benarbia, Seddick, additional, Beaudreuil, Severine, additional, Benyaghla, Sidi Ali, additional, Duquennoy, Simon, additional, Baluta, Simona, additional, Boncila, Simona, additional, Mzoughi, Sonia, additional, Ribal, Sonia, additional, Acamer, Sophie, additional, Chauvet, Sophie, additional, Girerd, Sophie, additional, Ozenne, Sophie, additional, Parahy, Sophie, additional, Duval, Sophie Rubens, additional, Taque, Sophie, additional, Menouer, Soraya, additional, Chargui, Soumaya, additional, Bataille, Stanislas, additional, Barbier, Stephane, additional, Billion, Stephane, additional, Roueff, Stephane, additional, Torner, Stephane, additional, Martin, Stephane Jean, additional, Coupel, Stephanie, additional, Cloarec, Sylvie, additional, Lavaud, Sylvie, additional, Leou, Sylvie, additional, Chatelet, T., additional, Onesta, Tania, additional, Benhabib, Tassadit, additional, Bensalem, Tayeb, additional, Dimulescu, Theodora, additional, Sawadogo, Theophile, additional, Hitze, Thibault Dolley, additional, Baranger, Thierry, additional, Boudemaghe, Thierry, additional, Hannedouche, Thierry, additional, Krummel, Thierry, additional, Milcent, Thierry, additional, Dervaux, Thomas, additional, Guincestre, Thomas, additional, Kofman, Thomas, additional, Raphael, Thomas, additional, Sadreux, Thomas, additional, Ulinski, Tim, additional, Roger, Tiphaine Guyon, additional, Serrato, Tomas, additional, Kofman, Tomek, additional, Wong, Tony, additional, Boubia, Toufik, additional, Gbindoun, Ubald Assogba, additional, Khuzaie, Usama, additional, Caudwell, Valerie, additional, Chatelet, Valerie, additional, Crougneau, Valerie, additional, De Precigout, Valerie, additional, Drouillat, Valerie, additional, Galantine, Valerie, additional, Hugot, Valerie Granveau, additional, Leroy, Valerie, additional, Boubia, Veronique, additional, Falque, Veronique, additional, Fournier, Veronique, additional, Queron, Veronique, additional, Viviani, Veronique, additional, Gueuttin, Victor, additional, Panescu, Victor, additional, Calonge, Victorio Menoyo, additional, Nguyen, Viet, additional, Allot, Vincent, additional, Delattre, Vincent, additional, Leduc, Vincent, additional, Pradier, Vincent, additional, Aglae, Violaine Emal, additional, Badulescu, Viorica, additional, Molina, Virginia, additional, Besson, Virginie, additional, Chaigne, Virginie, additional, Jaber, Waddah, additional, Boudi, Wael, additional, El Haggan, Wael, additional, Guillon, Wen Qin, additional, Aneni, Wided Tabbi, additional, Hanf, William, additional, Kohn, Wladimir, additional, Bellenfant, Xavier, additional, Gaudry, Xavier Moreau, additional, Delmas, Yahsou, additional, Knefati, Yannick, additional, Saingra, Yannick, additional, Tirolien, Yannick, additional, Mann, Youssef, additional, Brunak, Yvan, additional, Dimitrov, Yves, additional, Doussy, Yves, additional, Tanter, Yves, additional, Benabid, Zaid, additional, Soltani, Zaara, additional, Boukerroucha, Zacharia, additional, Takla, Zafer, additional, Ramanantsialonina, Zana, additional, Dickson, Zara, additional, Tubail, Zead, additional, Pour, Zoe Koochaki, additional, Boukhalfa, Zohra, additional, and Jacquot, Zohra, additional
Published: 2020
Full Text: View/download PDF

19. Fasting Urinary Osmolality, CKD Progression, and Mortality: A Prospective Observational Study

Author: Tabibzadeh, Nahid, primary, Wagner, Sandra, additional, Metzger, Marie, additional, Flamant, Martin, additional, Houillier, Pascal, additional, Boffa, Jean-Jacques, additional, Vrtovsnik, Francois, additional, Thervet, Eric, additional, Stengel, Bénédicte, additional, Haymann, Jean-Philippe, additional, Livrozet, Marine, additional, Letavernier, Emmanuel, additional, Ronco, Pierre, additional, Fessi, Hafedh, additional, Vidal-Petiot, Emmanuelle, additional, Daugas, Eric, additional, du Halgouet, Caroline, additional, de La Faille, Renaud, additional, Maruani, Gerard, additional, Vallet, Marion, additional, Nicolet-Barousse, Laurence, additional, Karras, Alexandre, additional, and Jacquot, Christian, additional
Published: 2019
Full Text: View/download PDF

20. A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

Author: Salou, Marion, primary, Legoux, François, additional, Gilet, Jules, additional, Darbois, Aurélie, additional, du Halgouet, Anastasia, additional, Alonso, Ruby, additional, Richer, Wilfrid, additional, Goubet, Anne-Gaëlle, additional, Daviaud, Céline, additional, Menger, Laurie, additional, Procopio, Emanuele, additional, Premel, Virginie, additional, and Lantz, Olivier, additional
Published: 2018
Full Text: View/download PDF

21. Peritoneal dialysis

Author: J. Liu, Y. Liu, Y. Xu, X. Zhao, J. Qian, B. Sun, C. Xing, R. Kanda, C. Hamada, T. Nakano, K. Wakabayashi, H. Io, S. Horikoshi, Y. Tomino, N. Ishimatsu, T. Miyamoto, H. Morimoto, J. Nakamata, R. Baba, K. Kanegae, R. Serino, N. Kabashima, Y. Otsuji, Y. Doi, M. Tamura, T. Kusumoto, K. Fukami, S.-I. Yamagishi, S. Ueda, Y. Kaida, T. Hazama, Y. Nakayama, R. Ando, N. Obara, S. Okuda, M. Matsumoto, Y. Furuno, H. Bang-Gee, L. Mazzotta, A. Rosati, A. Carlini, V. T. Henriques, E. Zangiacomi Martinez, J. C. Divino-Filho, R. Pecoits-Filho, J. A. Cardeal Da Costa, T. Gama Axelsson, B. Lindholm, J. J. Carrero, O. Heimburger, P. Stenvinkel, A. R. Qureshi, M. Akazawa, T. Uno, E. Kanda, Y. Maeda, M. Aktsiali, S. Antonopoulou, K. Tsiolaki, N. Bakirtzi, A. Patrinou, M. Georgopoulou, P. Liaveri, N. Afentakis, G. Tsirpanlis, T. Hasegawa, H. Nishiwaki, M. Hirose, D. Komukai, H. Tayama, F. Koiwa, A. Yoshimura, S. L. Lui, S. Lui, S. Yung, C. Tang, F. Ng, W. K. Lo, T. M. Chan, H. M. Koo, F. M. Doh, D. E. Yoo, H. J. Oh, T.-H. Yoo, K. H. Choi, S.-W. Kang, D. S. Han, S. H. Han, N. Fernandes, M. G. Bastos, M. R. Gianotti Franco, A. Chaoubah, M. D. Gloria Lima, S. Kang, J. Do, K. Cho, J. Park, K. Yoon, J.-B. Chen, B.-C. Cheng, T.-C. Chen, Y.-J. Su, C.-H. Wu, Y. Park, J. Jeon, M. Tsikeloudi, P. Pateinakis, K. Patsatsi, E. Manou, D. Sotiriadis, D. Tsakiris, L. Teixeira, A. Rodrigues, M. J. Carvalho, A. Cabrita, D. Mendonca, M. Bruschi, G. Candiano, L. Santucci, S. Luzio, R. Cannavo, G. M. Ghiggeri, E. Verrina, Y. Varadarajan, B. Raju, K.-H. Cho, J.-W. Park, K.-W. Yoon, T.-W. Kim, M. Kimmel, N. Braun, J. Latus, M. D. Alscher, D. Struijk, S. Van Esch, R. T. Krediet, T. Van den Beukel, T. Hoekstra, L. Tirapani, K. De Andrade Bastos, M. Bastos, F. Dekker, T. Yasuhisa, H. Kanai, K. Harada, Y. Kawai, H. Sugiyama, Y. Ito, K. Tsuruya, H. Yoshida, H. Maruyama, S. Goto, M. Nakayama, H. Nakamoto, H. Morinaga, S. Matsuo, H. Makino, M. C. DI Gioia, P. Gallar, N. Laso, I. Rodriguez, G. Cobo, A. Oliet, J. Hynostroza, J. C. Herrero, C. Mon, M. Ortiz, A. Vigil, T. Tomo, J. Portoles, S. Uta, A. M. Tato, P. Lopez-Sanchez, M. Rivera, R. Rodriguez-Pena, G. Del Peso, M. Ortega, C. Felipe, E. Tsampikaki, G. Aperis, A. Kaikis, C. Paliouras, N. Karvouniaris, M. Maragaki, P. Alivanis, B. Kortus-Gotze, T. Hoferhusch, J. Hoyer, F. Martino, M. Kaushik, M. P. Rodighiero, C. Creapldi, C. Ronco, A. Lacquaniti, V. Donato, M. R. Fazio, S. Lucisano, V. Cernaro, R. Lupica, M. Buemi, C. Aloisi, N. Bavbek Ruzgaresen, S. Secilmis, H. Yilmaz, A. Akcay, M. Duranay, N. Akalin, M. R. Altiparmak, S. Trabulus, A. S. Yalin, R. Ataman, K. Serdengecti, K. Schneider, B. Bator, B. Niko, F. Peter, C. Ulmer, L. Joerg, K. Martin, B. Dagmar, O. German, R. Fabian, D. Juergen, S. Stephan, A. Dominik, P. Fritz, B. Rettenmaier, S. Hirschburger, S. Segerer, D. Biegger, T. Lang, G. Ott, M. Habib, M. Korte, M. Hagen, F. Dor, M. Betjes, R. Zietse, C. Scharpf, T. I. Chang, D. H. Shin, D.-S. Han, H. Y. Choi, Y. K. Lee, B. S. Kim, T. H. Yoo, H. C. Park, H. Y. Lee, N. Horimoto, K. Tuji, S. Kitamura, R. Isshiki, M. Iwagami, D. Tsutsumi, Y. Mochida, K. Ishioka, M. Oka, K. Maesato, H. Moriya, T. Ohtake, S. Hidaka, S. Kobayashi, C. Higuchi, Y. Tanihata, M. Ishii, H. Sugimoto, N. Sato, A. Kyono, T. Ogawa, H. Nishimura, K. Otsuka, J.-Y. Do, C. Du Halgouet, A. Latifa, V. Anne Sophie, D. Emmanuel, R. Christine, V. Francois, T. Grzelak, L. Czyzewska-Majchrzak, M. Kramkowska, H. Witmanowski, K. Czyzewska, K. Janda, M. Krzanowski, P. Dumnicka, W. Sulowicz, M. Rroji, S. Seferi, M. Barbullushi, E. Likaj, E. Petrela, N. Thereska, G. Cabiddu, E. Dessi, A. Arceri, P. Laura, E. Manca, M. Conti, R. Cao, A. Pani, C.-T. Liao, O. Vega Vega, A. Mendoza de la Garza, R. Correa-Rotter, A. Ueda, K. Nagai, M. Morimoto, A. Hirayama, S. Owada, Y. Tonozuka, C. Saito, K. Yamagata, A. Matsuda, Y. Tayama, M. Iwanaga, C. Noiri, M. Hatano, T. Kiba, K. Kanozawa, H. Katou, H. Hasegawa, T. Mitarai, S. Ros-Ruiz, L. Fuentes-Sanchez, C. Jironda-Gallegos, E. Gutierrez-Vilches, P. Garcia-Frias, D. Hernandez-Marrero, S. Lee, X. Lai, W. Chen, Z. Guo, M. Braide, V. Cristina, S. G. Popa, M. Maria, M. Eugen, P. DI Loreto, N. Spahia, L. O. Sanchez Macias, K. I. Lares Castellanos, J. A. Hernandez Pacheco, R. Correa Rotter, A. Pedro Ventura, S. Olivia, V. Joana, F. Francisco, C. Maria Joao, C. Antonio, A. S. Rodrigues, N. Atas, Y. Erten, K. Onec, S. Inal, S. Topal, A. Akyel, B. Celik, G. U. Okyay, Y. Tavil, M. Zeiler, T. Monteburini, R. M. Agostinelli, R. Marinelli, S. Santarelli, C. Yaylaci, G. Sahin, G. Guz, S. Sindel, A. Pinho, A. Malho Guedes, A. Fragoso, H. Carreira, I. Pinto, I. Bernardo, P. Leao, B. Kusnierz-Cabala, A. Krasniak, E. Chowaniec, B. Tabor-Ciepiela, K. Turkmen, O. Ozbek, M. Kayrak, C. Samur, I. Guler, H. Z. Tonbul, K. Rusai, R. Herzog, K. Kratochwill, L. Kuster, C. Aufricht, C.-M. Meier, D. Fliser, M. K. Schilling, M. Klingele, M. Fukasawa, M. Takeda, M. Kamiyama, Y. R. Song, H. J. Kim, S. G. Kim, J.-K. Kim, J. W. Noh, J. W. Yoon, and J.-R. Koo
Subjects: Transplantation, Nephrology
Published: 2012
Full Text: View/download PDF

22. A conserved transcriptional program for MAIT cells across mammalian evolution

Author: Bugaut, Hélène, El Morr, Yara, Mestdagh, Martin, Darbois, Aurélie, Paiva, Rafael A., Salou, Marion, Perrin, Laetitia, Fürstenheim, Mariela, du Halgouet, Anastasia, Bilonda-Mutala, Linda, Le Gac, Anne-Laure, Arnaud, Manon, El Marjou, Ahmed, Guerin, Coralie, Chaiyasitdhi, Atitheb, Piquet, Julie, Smadja, David M., Cieslak, Agata, Ryffel, Bernhard, Maciulyte, Valdone, Turner, James M.A., Bernardeau, Karine, Montagutelli, Xavier, Lantz, Olivier, and Legoux, François
Abstract: Mucosal-associated invariant T (MAIT) cells harbor evolutionarily conserved TCRs, suggesting important functions. As human and mouse MAIT functional programs appear distinct, the evolutionarily conserved MAIT functional features remain unidentified. Using species-specific tetramers coupled to single-cell RNA sequencing, we characterized MAIT cell development in six species spanning 110 million years of evolution. Cross-species analyses revealed conserved transcriptional events underlying MAIT cell maturation, marked by ZBTB16 induction in all species. MAIT cells in human, sheep, cattle, and opossum acquired a shared type-1/17 transcriptional program, reflecting ancestral features. This program was also acquired by human iNKT cells, indicating common differentiation for innate-like T cells. Distinct type-1 and type-17 MAIT subsets developed in rodents, including pet mice and genetically diverse mouse strains. However, MAIT cells further matured in mouse intestines to acquire a remarkably conserved program characterized by concomitant expression of type-1, type-17, cytotoxicity, and tissue-repair genes. Altogether, the study provides a unifying view of the transcriptional features of innate-like T cells across evolution.
Published: 2024
Full Text: View/download PDF

23. 0122: Peritoneal dialysis and heart failure: designing of the heart module in the French speaking peritoneal dialysis registry (RDPLF)

Author: Cécile Courivaud, Caroline du Halgouet, Isabelle Vernier, Christian Verger, Raymond Azar, Marie-Béatrice Nogier, Guillaume Jondeau, Thierry Lobbedez, M.J. Krier-Coudert, Angelo Testa, Jacques Chanliau, Belkacem Issad, Celia Lessoré, François Vrtovsnik, Didier Aguilera, and Max Dratwa
Subjects: medicine.medical_specialty, Ejection fraction, Acute decompensated heart failure, business.industry, medicine.medical_treatment, Peritonitis, macromolecular substances, medicine.disease, Comorbidity, Peritoneal dialysis, Surgery, Heart failure, Internal medicine, Cohort, Medicine, business, Cardiology and Cardiovascular Medicine, Kidney disease
Abstract: Heart failure (HF) is a frequent and severe comorbidity in dialysis patients (pts); conversely, 30% of pts in the large Acute Decompensated Heart Failure National Registry had moderate to severe chronic kidney disease and 5% were receiving dialysis therapy. Refractory HF is a not uncommon indication for peritoneal ultrafiltration although its benefits have been unconsistently reported through mainly retrospective or monocentric studies. The main objectives of the “heart module” are to prospectively collect data related to cardiac status in PD pts and to allow longitudinal follow-up of cardiac- and dialysisrelated parameters in HF ptsMethodsThe RDPLF constitutes the largest recruiting observational cohort of French speaking PD pts, with coverage estimated at 98,3% of PD in France in 2013. All centers complete a set of core modules covering sociodemographics and basic clinical information, peritonitis episodes, and outcomes. Optional specialized modules are available. The heart module consists of baseline followed by quarterly collection of information related to cardiac disease, hospitalization rate, and dialysis-related parameters.Results14 centers volunteered to participate since the heart module was launched in February 2013, now totalizing 75 pts. PD was initiated because of HF in 73%. Mean eGFR was 22±14ml/mn/1.73m2 with GFR>15ml/mn/ 1.73m2 in 69%. Half of the pts had echocardiographic Left Ventricular Ejection Fraction (LVEF)
Published: 2015
Full Text: View/download PDF

24. Complications infectieuses en transplantation rénale, étude de cohorte entre 1999 et 2012

Author: C. Randoux, L. Champion, C. du Halgouet, Eric Daugas, François Vrtovsnik, L. Azeroual, Denis Glotz, and C. Renoux
Subjects: Nephrology
Published: 2013
Full Text: View/download PDF

25. A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

Author: Salou, Marion, Legoux, François, Gilet, Jules, Darbois, Aurélie, du Halgouet, Anastasia, Alonso, Ruby, Richer, Wilfrid, Goubet, Anne-Gaëlle, Daviaud, Céline, Menger, Laurie, Procopio, Emanuele, Premel, Virginie, and Lantz, Olivier
Abstract: Mucosal-associated invariant T (MAIT) cells are abundant T cells with unique specificity for microbial metabolites. MAIT conservation along evolution indicates important functions, but their low frequency in mice has hampered their detailed characterization. Here, we performed the first transcriptomic analysis of murine MAIT cells. MAIT1 (RORγtneg) and MAIT17 (RORγt+) subsets were markedly distinct from mainstream T cells, but quasi-identical to NKT1 and NKT17 subsets. The expression of similar programs was further supported by strong correlations of MAIT and NKT frequencies in various organs. In both mice and humans, MAIT subsets expressed gene signatures associated with tissue residency. Accordingly, parabiosis experiments demonstrated that MAIT and NKT cells are resident in the spleen, liver, and lungs, with LFA1/ICAM1 interactions controlling MAIT1 and NKT1 retention in spleen and liver. The transcriptional program associated with tissue residency was already expressed in thymus, as confirmed by adoptive transfer experiments. Altogether, shared thymic differentiation processes generate “preset” NKT and MAIT subsets with defined effector functions, associated with specific positioning into tissues.
Published: 2019
Full Text: View/download PDF

26. Complications infectieuses en transplantation rénale, étude de cohorte entre 1999 et 2012

Author: Champion, L., primary, Renoux, C., additional, Randoux, C., additional, du Halgouet, C., additional, Azeroual, L., additional, Vrtovsnik, F., additional, Glotz, D., additional, and Daugas, E., additional
Published: 2013
Full Text: View/download PDF

27. Facteurs médicaux et non médicaux limitant le développement de la dialyse péritonéale : analyse d’un programme d’information prédialyse

Author: Du Halgouet, C., primary, Azeroual, L., additional, Verhoeven, A.-S., additional, Dupuis, E., additional, Randoux, C., additional, Daugas, E., additional, and Vrtovsnik, F., additional
Published: 2012
Full Text: View/download PDF

28. Peritoneal dialysis

Author: Liu, J., primary, Liu, J., additional, Liu, Y., additional, Xu, Y., additional, Zhao, X., additional, Qian, J., additional, Sun, B., additional, Xing, C., additional, Kanda, R., additional, Hamada, C., additional, Nakano, T., additional, Wakabayashi, K., additional, Io, H., additional, Horikoshi, S., additional, Tomino, Y., additional, Ishimatsu, N., additional, Miyamoto, T., additional, Morimoto, H., additional, Nakamata, J., additional, Baba, R., additional, Kanegae, K., additional, Serino, R., additional, Kabashima, N., additional, Otsuji, Y., additional, Doi, Y., additional, Tamura, M., additional, Kusumoto, T., additional, Fukami, K., additional, Yamagishi, S.-I., additional, Ueda, S., additional, Kaida, Y., additional, Hazama, T., additional, Nakayama, Y., additional, Ando, R., additional, Obara, N., additional, Okuda, S., additional, Matsumoto, M., additional, Furuno, Y., additional, Bang-Gee, H., additional, Mazzotta, L., additional, Rosati, A., additional, Carlini, A., additional, Henriques, V. T., additional, Zangiacomi Martinez, E., additional, Divino-Filho, J. C., additional, Pecoits-Filho, R., additional, Cardeal Da Costa, J. A., additional, Gama Axelsson, T., additional, Lindholm, B., additional, Carrero, J. J., additional, Heimburger, O., additional, Stenvinkel, P., additional, Qureshi, A. R., additional, Akazawa, M., additional, Uno, T., additional, Kanda, E., additional, Maeda, Y., additional, Aktsiali, M., additional, Antonopoulou, S., additional, Tsiolaki, K., additional, Bakirtzi, N., additional, Patrinou, A., additional, Georgopoulou, M., additional, Liaveri, P., additional, Afentakis, N., additional, Tsirpanlis, G., additional, Hasegawa, T., additional, Nishiwaki, H., additional, Hirose, M., additional, Komukai, D., additional, Tayama, H., additional, Koiwa, F., additional, Yoshimura, A., additional, Lui, S. L., additional, Lui, S., additional, Yung, S., additional, Tang, C., additional, Ng, F., additional, Lo, W. K., additional, Chan, T. M., additional, Koo, H. M., additional, Doh, F. M., additional, Yoo, D. E., additional, Oh, H. J., additional, Yoo, T.-H., additional, Choi, K. H., additional, Kang, S.-W., additional, Han, D. S., additional, Han, S. H., additional, Fernandes, N., additional, Bastos, M. G., additional, Gianotti Franco, M. R., additional, Chaoubah, A., additional, Gloria Lima, M. D., additional, Kang, S., additional, Do, J., additional, Cho, K., additional, Park, J., additional, Yoon, K., additional, Chen, J.-B., additional, Cheng, B.-C., additional, Chen, T.-C., additional, Su, Y.-J., additional, Wu, C.-H., additional, Park, Y., additional, Jeon, J., additional, Tsikeloudi, M., additional, Pateinakis, P., additional, Patsatsi, K., additional, Manou, E., additional, Sotiriadis, D., additional, Tsakiris, D., additional, Teixeira, L., additional, Rodrigues, A., additional, Carvalho, M. J., additional, Cabrita, A., additional, Mendonca, D., additional, Bruschi, M., additional, Candiano, G., additional, Santucci, L., additional, Luzio, S., additional, Cannavo, R., additional, Ghiggeri, G. M., additional, Verrina, E., additional, Varadarajan, Y., additional, Raju, B., additional, Cho, K.-H., additional, Park, J.-W., additional, Yoon, K.-W., additional, Kim, T.-W., additional, Kimmel, M., additional, Braun, N., additional, Latus, J., additional, Alscher, M. D., additional, Struijk, D., additional, Van Esch, S., additional, Krediet, R. T., additional, Van den Beukel, T., additional, Hoekstra, T., additional, Tirapani, L., additional, De Andrade Bastos, K., additional, Bastos, M., additional, Dekker, F., additional, Yasuhisa, T., additional, Kanai, H., additional, Harada, K., additional, Kawai, Y., additional, Sugiyama, H., additional, Ito, Y., additional, Tsuruya, K., additional, Yoshida, H., additional, Maruyama, H., additional, Goto, S., additional, Nakayama, M., additional, Nakamoto, H., additional, Morinaga, H., additional, Matsuo, S., additional, Makino, H., additional, DI Gioia, M. C., additional, Gallar, P., additional, Laso, N., additional, Rodriguez, I., additional, Cobo, G., additional, Oliet, A., additional, Hynostroza, J., additional, Herrero, J. C., additional, Mon, C., additional, Ortiz, M., additional, Vigil, A., additional, Tomo, T., additional, Portoles, J., additional, Uta, S., additional, Tato, A. M., additional, Lopez-Sanchez, P., additional, Rivera, M., additional, Rodriguez-Pena, R., additional, Del Peso, G., additional, Ortega, M., additional, Felipe, C., additional, Tsampikaki, E., additional, Aperis, G., additional, Kaikis, A., additional, Paliouras, C., additional, Karvouniaris, N., additional, Maragaki, M., additional, Alivanis, P., additional, Kortus-Gotze, B., additional, Hoferhusch, T., additional, Hoyer, J., additional, Martino, F., additional, Kaushik, M., additional, Rodighiero, M. P., additional, Creapldi, C., additional, Ronco, C., additional, Lacquaniti, A., additional, Donato, V., additional, Fazio, M. R., additional, Lucisano, S., additional, Cernaro, V., additional, Lupica, R., additional, Buemi, M., additional, Aloisi, C., additional, Bavbek Ruzgaresen, N., additional, Secilmis, S., additional, Yilmaz, H., additional, Akcay, A., additional, Duranay, M., additional, Akalin, N., additional, Altiparmak, M. R., additional, Trabulus, S., additional, Yalin, A. S., additional, Ataman, R., additional, Serdengecti, K., additional, Schneider, K., additional, Bator, B., additional, Niko, B., additional, Peter, F., additional, Ulmer, C., additional, Joerg, L., additional, Martin, K., additional, Dagmar, B., additional, German, O., additional, Fabian, R., additional, Juergen, D., additional, Stephan, S., additional, Dominik, A., additional, Fritz, P., additional, Rettenmaier, B., additional, Hirschburger, S., additional, Segerer, S., additional, Biegger, D., additional, Lang, T., additional, Ott, G., additional, Habib, M., additional, Korte, M., additional, Hagen, M., additional, Dor, F., additional, Betjes, M., additional, Zietse, R., additional, Scharpf, C., additional, Chang, T. I., additional, Shin, D. H., additional, Han, D.-S., additional, Choi, H. Y., additional, Lee, Y. K., additional, Kim, B. S., additional, Yoo, T. H., additional, Park, H. C., additional, Lee, H. Y., additional, Horimoto, N., additional, Tuji, K., additional, Kitamura, S., additional, Isshiki, R., additional, Iwagami, M., additional, Tsutsumi, D., additional, Mochida, Y., additional, Ishioka, K., additional, Oka, M., additional, Maesato, K., additional, Moriya, H., additional, Ohtake, T., additional, Hidaka, S., additional, Kobayashi, S., additional, Higuchi, C., additional, Tanihata, Y., additional, Ishii, M., additional, Sugimoto, H., additional, Sato, N., additional, Kyono, A., additional, Ogawa, T., additional, Nishimura, H., additional, Otsuka, K., additional, Do, J.-Y., additional, Du Halgouet, C., additional, Latifa, A., additional, Anne Sophie, V., additional, Emmanuel, D., additional, Christine, R., additional, Francois, V., additional, Grzelak, T., additional, Czyzewska-Majchrzak, L., additional, Kramkowska, M., additional, Witmanowski, H., additional, Czyzewska, K., additional, Janda, K., additional, Krzanowski, M., additional, Dumnicka, P., additional, Sulowicz, W., additional, Rroji, M., additional, Seferi, S., additional, Barbullushi, M., additional, Likaj, E., additional, Petrela, E., additional, Thereska, N., additional, Cabiddu, G., additional, Dessi, E., additional, Arceri, A., additional, Laura, P., additional, Manca, E., additional, Conti, M., additional, Cao, R., additional, Pani, A., additional, Liao, C.-T., additional, Vega Vega, O., additional, Mendoza de la Garza, A., additional, Correa-Rotter, R., additional, Ueda, A., additional, Nagai, K., additional, Morimoto, M., additional, Hirayama, A., additional, Owada, S., additional, Tonozuka, Y., additional, Saito, C., additional, Yamagata, K., additional, Matsuda, A., additional, Tayama, Y., additional, Iwanaga, M., additional, Noiri, C., additional, Hatano, M., additional, Kiba, T., additional, Kanozawa, K., additional, Katou, H., additional, Hasegawa, H., additional, Mitarai, T., additional, Ros-Ruiz, S., additional, Fuentes-Sanchez, L., additional, Jironda-Gallegos, C., additional, Gutierrez-Vilches, E., additional, Garcia-Frias, P., additional, Hernandez-Marrero, D., additional, Lee, S., additional, Lai, X., additional, Chen, W., additional, Guo, Z., additional, Braide, M., additional, Cristina, V., additional, Popa, S. G., additional, Maria, M., additional, Eugen, M., additional, DI Loreto, P., additional, Spahia, N., additional, Sanchez Macias, L. O., additional, Lares Castellanos, K. I., additional, Hernandez Pacheco, J. A., additional, Correa Rotter, R., additional, Pedro Ventura, A., additional, Olivia, S., additional, Joana, V., additional, Francisco, F., additional, Maria Joao, C., additional, Antonio, C., additional, Rodrigues, A. S., additional, Atas, N., additional, Erten, Y., additional, Onec, K., additional, Inal, S., additional, Topal, S., additional, Akyel, A., additional, Celik, B., additional, Okyay, G. U., additional, Tavil, Y., additional, Zeiler, M., additional, Monteburini, T., additional, Agostinelli, R. M., additional, Marinelli, R., additional, Santarelli, S., additional, Yaylaci, C., additional, Sahin, G., additional, Guz, G., additional, Sindel, S., additional, Pinho, A., additional, Malho Guedes, A., additional, Fragoso, A., additional, Carreira, H., additional, Pinto, I., additional, Bernardo, I., additional, Leao, P., additional, Kusnierz-Cabala, B., additional, Krasniak, A., additional, Chowaniec, E., additional, Tabor-Ciepiela, B., additional, Turkmen, K., additional, Ozbek, O., additional, Kayrak, M., additional, Samur, C., additional, Guler, I., additional, Tonbul, H. Z., additional, Rusai, K., additional, Herzog, R., additional, Kratochwill, K., additional, Kuster, L., additional, Aufricht, C., additional, Meier, C.-M., additional, Fliser, D., additional, Schilling, M. K., additional, Klingele, M., additional, Fukasawa, M., additional, Takeda, M., additional, Kamiyama, M., additional, Song, Y. R., additional, Kim, H. J., additional, Kim, S. G., additional, Kim, J.-K., additional, Noh, J. W., additional, Yoon, J. W., additional, and Koo, J.-R., additional
Published: 2012
Full Text: View/download PDF

29. Facteurs médicaux et non médicaux limitant le développement de la dialyse péritonéale : analyse d’un programme d’information prédialyse

Author: C. du Halgouet, C. Randoux, Eric Daugas, François Vrtovsnik, L. Azeroual, E. Dupuis, and A.-S. Verhoeven
Subjects: Nephrology
Published: 2012
Full Text: View/download PDF

30. Discussion sur la date de la façade nord du château de Josselin

Author: Hervé Du Halgouet
Subjects: Archeology, Visual Arts and Performing Arts, Architecture
Abstract: Du Halgouët Hervé. Discussion sur la date de la façade nord du château de Josselin. In: Bulletin Monumental, tome 75, année 1911. pp. 489-497.
Published: 1911
Full Text: View/download PDF

31. Le chartrier de Blain

Author: H. du Halgouet
Subjects: General Medicine
Abstract: Du Halgouet Hervé. Le chartrier de Blain. In: Annales de Bretagne. Tome 35, numéro 1, 1921. pp. 81-88.
Published: 1921
Full Text: View/download PDF

32. Murol : son château, ses environs.. / A. Du Halgouet

Author: Du Halgouet, A.. Auteur du texte, Auserve, Philippe (1940-....). Auteur du texte, Du Halgouet, A.. Auteur du texte, and Auserve, Philippe (1940-....). Auteur du texte
Abstract: Collection : Le Touriste en Auvergne ; 8, Contient une table des matières, Avec mode texte
Published: 1970

33. Le chartrier de Blain

Author: Du Halgouet, H., primary
Published: 1921
Full Text: View/download PDF

34. Association of plasma potassium with mortality and end-stage kidney disease in patients with chronic kidney disease under nephrologist care - The NephroTest study

Author: Wagner, Sandra, Metzger, Marie, Flamant, Martin, Houillier, Pascal, Haymann, Jean-Philippe, Vrtovsnik, François, Thervet, Eric, Boffa, Jean-Jacques, Massy, Ziad, Stengel, Bénédicte, Rossignol, Patrick, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Saclay, French-Clinical Research Infrastructure Network - F-CRIN [Paris] (Cardiovascular & Renal Clinical Trialists - CRCT ), Explorations fonctionnelles néphrologie - Rénales [AP-HP Hôpital Bichat-Claude-Bernard, Paris], AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre de Recherche des Cordeliers (CRC), Université Pierre et Marie Curie - Paris 6 (UPMC)-École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Physiologie - Explorations fonctionnelles [AP-HP HEGP, Paris], Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Néphrologie [Boulogne-Billancourt], Hôpital Ambroise Paré [AP-HP], Centre d'investigation clinique [Nancy] (CIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), The NephroTest cohort study was supported by grants from Inserm GIS-IreSP AO 8113LS TGIR, French Ministry of Health AOM 09114 and AOM 10245, Inserm AO8022LS, Agence de la Biomédecine R08156LL, AURA, and Roche 2009–152-447G., The NephroTest study group : Letavernier E, Ronco P, Fessi H, Daugas E, du Halgouet C, de La Faille R, d'Auzac C, Maruani G, Vallet M, Nicolet-Barousse L, Roland M, Jacquot C., Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Université Paris Diderot - Paris 7 (UPD7)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Néphrologie et Dialyses [CHU Tenon], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Européen Georges Pompidou [APHP] (HEGP), Centre de recherche en épidémiologie et santé des populations ( CESP ), Université de Versailles Saint-Quentin-en-Yvelines ( UVSQ ) -Université Paris-Sud - Paris 11 ( UP11 ) -Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale ( INSERM ), French-Clinical Research Infrastructure Network - F-CRIN [Paris] ( Cardiovascular & Renal Clinical Trialists - CRCT ), Centre de Recherche des Cordeliers ( CRC ), Université Paris Diderot - Paris 7 ( UPD7 ) -École pratique des hautes études ( EPHE ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Hôpital Européen Georges Pompidou [APHP] ( HEGP ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Tenon [APHP], Paris-Centre de Recherche Cardiovasculaire ( PARCC - U970 ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Hôpital Européen Georges Pompidou [APHP] ( HEGP ), AP-HP Hôpital Ambroise Paré (Boulogne-Billancourt), CIC-Nancy, Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy]-Institut National de la Santé et de la Recherche Médicale ( INSERM ), BMC, BMC, Université Pierre et Marie Curie - Paris 6 (UPMC)-École pratique des hautes études (EPHE), Service de Département de Néphrologie = Service de Néphrologie et Dialyses [CHU Tenon], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
Subjects: [SDV] Life Sciences [q-bio], Plasma potassium, Cardiovascular mortality, [ SDV ] Life Sciences [q-bio], Chronic kidney disease, [SDV]Life Sciences [q-bio], End-stage kidney disease, Hyperkalemia, Hypokalemia, Mortality
Abstract: International audience; AbstractBackgroundLow and high blood potassium levels are common and were both associated with poor outcomes in patients with chronic kidney disease (CKD). Whether such relationships may be altered in CKD patients receiving optimized nephrologist care is unknown.MethodsNephroTest is a hospital-based prospective cohort study that enrolled 2078 nondialysis patients (mean age: 59 ± 15 years, 66% men) in CKD stages 1 to 5 who underwent repeated extensive renal tests including plasma potassium (PK) and glomerular filtration rate (GFR) measured (mGFR) by 51Cr-EDTA renal clearance. Test reports included a reminder of recommended targets for each abnormal value to guide treatment adjustment. Main outcomes were cardiovascular (CV) and all-cause mortality before end-stage kidney disease (ESKD), and ESKD.ResultsAt baseline, median mGFR was 38.4 mL/min/1.73m2; prevalence of low PK (5 mmol/L) 6.4%; 74.4% of patients used angiotensin converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARB). After excluding 137 patients with baseline GFR
Published: 2016
Full Text: View/download PDF

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources

Refine your results

34 results on '"du Halgouet A"'

1. Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice

2. Protocol to expand and CRISPR-Cas9 genomic edit murine MAIT cells for subsequent in vivo studies

3. Role of MR1-driven signals and amphiregulin on the recruitment and repair function of MAIT cells during skin wound healing

4. Longitudinal Bone Loss Occurs at the Radius in CKD

5. Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

6. Fasting Urinary Osmolality, CKD Progression, and Mortality: A Prospective Observational Study

7. MAIT cells monitor intestinal dysbiosis and contribute to host protection during colitis.

8. A conserved transcriptional program for MAIT cells across mammalian evolution

9. Protocol to expand and CRISPR-Cas9 genomic edit murine MAIT cells for subsequent in vivo studies

10. Role of MR1-driven signals and amphiregulin on the recruitment and repair function of skin MAIT cells

11. In vivo study of MAIT cell tissue repair function

12. Mechanisms Underlying Mait Cell Ability to Promote Skin Wound Repair

13. Mechanisms Underlying Mait Cell Ability to Promote Skin Wound Repair

14. Fasting Urinary Osmolality, CKD Progression, and Mortality: A Prospective Observational Study

15. Longitudinal Bone Loss Occurs at the Radius in CKD

16. Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

17. A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

18. Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

19. Fasting Urinary Osmolality, CKD Progression, and Mortality: A Prospective Observational Study

20. A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

21. Peritoneal dialysis

22. A conserved transcriptional program for MAIT cells across mammalian evolution

23. 0122: Peritoneal dialysis and heart failure: designing of the heart module in the French speaking peritoneal dialysis registry (RDPLF)

24. Complications infectieuses en transplantation rénale, étude de cohorte entre 1999 et 2012

25. A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets

26. Complications infectieuses en transplantation rénale, étude de cohorte entre 1999 et 2012

27. Facteurs médicaux et non médicaux limitant le développement de la dialyse péritonéale : analyse d’un programme d’information prédialyse

28. Peritoneal dialysis

29. Facteurs médicaux et non médicaux limitant le développement de la dialyse péritonéale : analyse d’un programme d’information prédialyse

30. Discussion sur la date de la façade nord du château de Josselin

31. Le chartrier de Blain

32. Murol : son château, ses environs.. / A. Du Halgouet

33. Le chartrier de Blain

34. Association of plasma potassium with mortality and end-stage kidney disease in patients with chronic kidney disease under nephrologist care - The NephroTest study

Catalog

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Publication Type

Journal

Database

Publisher

34 results on '"du Halgouet A"'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources