1. Same versus separate sessions of endoscopic ultrasound-guided fine-needle biopsy and endoscopic retrograde cholangiopancreatography for distal malignant biliary obstruction: a propensity score-matched study.
- Author
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Crinò, Stefano Francesco, Zorzi, Alberto, Tavian, Piero, De Pretis, Nicolò, Facciorusso, Antonio, Dhar, Jahnvi, Samanta, Jayanta, Sina, Sokol, Manfrin, Erminia, Frulloni, Luca, and Conti Bellocchi, Maria Cristina
- Subjects
ENDOSCOPIC ultrasonography ,LENGTH of stay in hospitals ,PATIENTS' attitudes ,MEDICAL drainage ,PANCREATIC cancer ,ENDOSCOPIC retrograde cholangiopancreatography ,NEEDLE biopsy - Abstract
Background: Same-session endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) is an attractive policy for patients with distal malignant biliary obstruction (DMBO) requiring fine-needle biopsy (FNB) and biliary drainage. However, scanty and conflicting data exists regarding safety and efficacy when comparing these two procedures performed in same versus separate sessions. Methods: Single-center, retrospective, propensity score-matched study including patients with DMBO who underwent EUS-FNB followed by ERCP during the same or separate sessions. The primary outcome was the safety of the procedure [number of patients experiencing adverse events (AEs), overall AEs, its severity, post-ERCP pancreatitis (PEP)]. Secondary outcomes were successful ERCP, use of advanced cannulation techniques, EUS-FNB adequacy, length of hospital stay, overall procedure time, and time to recurrent biliary obstruction. Results: After propensity matching, 87 patients were allocated to each group. AEs developed in 23 (26.4%) vs. 17 (19.5%) patients in the same and separate sessions group, respectively (p = 0.280). The overall number, the severity of AEs, and the rate of PEP were similar in the two groups. Secondary outcome parameters were also comparable in the 2 groups. Conclusions: Same-session EUS-FNB followed by ERCP with biliary drainage is safe and does not impair technical outcomes of tissue adequacy and biliary cannulation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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