763 results on '"dish"'
Search Results
2. Distinct characteristics and progression patterns of facet joint structural lesions in radiographic axial spondyloarthritis.
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Liao, Simin, Cheng, Liuquan, Zhao, Zheng, Zhu, Jian, and Huang, Feng
- Subjects
SPONDYLOARTHROPATHIES ,ARTHRITIS diagnosis ,DISEASE progression ,ZYGAPOPHYSEAL joint ,DATA analysis - Abstract
Background: Both vertebral bodies and posterior elements of the vertebrae (facet joints, FJ) can engage in bone formation in radiographic axial spondyloarthritis (r-axSpA). However, little is known about the specific structural lesions and progression patterns of FJs in r-axSpA. Objectives: To identify specific lesions related to r-axSpA and to investigate the distinct progression patterns by comparing the FJ changes of r-axSpA with that of diffuse idiopathic skeletal hyperostosis (DISH), osteoarthritis (OA), and control group (CG). Design: Single-center, retrospective study. Longitudinal imaging data were retrieved and collected. Methods: Age- and sex-matched patients with complete thoracic and lumbar spine computed tomography (CT) data were included and their bilateral FJs were assessed. FJ changes were divided into erosions, ankylosis, joint-space narrowing, osteophytes, subchondral sclerosis, subchondral cysts, and vacuum phenomena. Average progressed year was defined as "number of changed vertebrae × interval years"/number of changed vertebrae. Results: In all, 50 patients in each group were included. Subchondral cysts and vacuum phenomena were not observed. Bilateral FJ ankylosis (FJA)/erosions in the thoracic and lumbar spine, and unilateral ankylosis/erosions in T1–4, T9–12 were significantly more common in r-axSpA. Joint-space narrowing/osteophytes/subchondral sclerosis were significantly more common in DISH and OA. FJ lesions progressed in 56.34% of vertebrae of r-axSpA. The most common pattern was "FJ normal advanced to ankylosis" (17.54%) which required 2.63 years. It was followed by "erosions advanced to ankylosis" (12.3%) which took 2.05 years, and by "normal FJ advanced to erosions" (11.04%) which took 2.29 years, respectively. Degenerative changes could also progress to FJ erosions/ankylosis (24.83%). The majority pattern in DISH/OA was "FJ changes advanced to subchondral sclerosis/osteophytes/joint-space narrowing." Conclusion: Bilateral FJA/erosions are r-axSpA-specific lesions. The specific progression pattern for r-axSpA was "FJ changes advanced to ankylosis/erosions." Repeated CT examination in intervals of at least 2 years will be more appropriate for monitoring FJ progression. [ABSTRACT FROM AUTHOR]
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- 2024
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3. 蔬菜烹饪后在不同储藏条件下亚硝酸盐含量的 变化分析.
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赵 欣, 项海龙, 李建超, and 聂陶然
- Abstract
Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
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4. Prevalence of diffuse idiopathic skeletal hyperostosis (DISH) and early-phase DISH across the lifespan of an American population.
- Author
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Fournier, Dale E, Leung, Andrew E, Battié, Michele C, and Séguin, Cheryle A
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BONE density , *RESEARCH funding , *STATISTICAL sampling , *COMPUTED tomography , *SPINAL osteophytosis , *RETROSPECTIVE studies , *DESCRIPTIVE statistics , *CONTINUUM of care , *EXOSTOSIS , *LONGEVITY , *THORACIC vertebrae - Abstract
Objectives DISH is a common musculoskeletal disorder; however, the imaging features and disease continuum from early to advanced stages is poorly understood. The purpose of this study was to evaluate the prevalence of DISH and early-phase DISH in an American population and to assess the extent and pattern of ectopic mineralization across the thoracic spine. Methods Data were retrieved in collaboration with the Rochester Epidemiology Project. We conducted a retrospective image evaluation of a sample of individuals over 19 years of age with CT of the thoracic spine from a Northern US catchment area. Stratified random sampling by age and sex was used to populate the study. We examined the prevalence and extent of ectopic mineralization along the thoracic spine using previously established criteria. Results A total of 1536 unique images (766 female and 770 male individuals) including 16 710 motion segments were evaluated for imaging features of the continuum of DISH. Collectively, 40.5% of all motion segments evaluated displayed evidence of ectopic mineralization in the thoracic spine. The prevalence of early-phase DISH was 13.2% (10.4% of female and 15.8% of male individuals). The prevalence of established DISH was 14.2% (7.4% of female and 20.9% of male individuals). Remarkable heterogeneity was detected in individuals within each disease classification, based on the extent of the thoracic spine affected and degree of mineralization. Conclusions The continuum of imaging features associated with DISH is detected in more than one in four adults and both sexes in an American population. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Anterior cervical osteotomy of diffuse idiopathic skeletal hyperostosis lesions with computer‐assisted navigation surgery: A case report.
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Avrumova, Fedan, Goldman, Samuel N., Altorfer, Franziska, Paschal, Gregory K., and Lebl, Darren R.
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COMPUTER-assisted surgery , *OSTEOTOMY , *THORACIC vertebrae , *EXOSTOSIS , *OSSIFICATION , *DEGLUTITION disorders - Abstract
Key Clinical Message: Diffuse idiopathic skeletal hyperostosis (DISH) involves spine ligament ossification. Computer‐assisted navigation (CAN) effectively aids complex surgeries, such as anterior cervical osteotomy, to alleviate progressive DISH‐related dysphagia. We describe a 68‐year‐old man with sudden onset dysphagia to both solids and liquids. Radiographic Imaging revealed DISH lesions from C2 down to the thoracic spine. The patient was successfully treated with CAN anterior osteotomy and resection of DISH lesions from C3–C6 and had complete symptom relief within 2 weeks post‐operatively. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Spinal Fracture in a 45-year-old Woman with Paraplegia and Diffuse Idiopathic Skeletal Hyperostosis
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Roubakha, Mikhail and Homer, Ronald
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DISH ,spinal fracture - Published
- 2022
7. Step‐By‐Step Surgery for Diffuse Idiopathic Skeletal Hyperostosis (DISH) of the Cervical Spine.
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Liberale, Carlotta, Bassani, Sara, Nocini, Riccardo, and Molteni, Gabriele
- Abstract
Diffuse idiopathic skeletal hyperostosis (DISH) is a disease that can cause symptoms such as difficulty swallowing or breathing. Surgical treatment for DISH can be effective in restoring normal functions. This article presents a case study of an 86-year-old man with DISH who underwent surgery to remove osteophytes in the cervical spine. The surgery was successful, and the patient experienced improvement in dysphagia and respiratory symptoms. The article also discusses the causes and mechanisms of dysphagia in DISH and the importance of a multidisciplinary approach to treatment. [Extracted from the article]
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- 2024
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8. Examples of Using SEMS Modules
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Gorodetskiy, Andrey E., Tarasova, Irina L., Kacprzyk, Janusz, Series Editor, Gorodetskiy, Andrey E., and Tarasova, Irina L.
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- 2023
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9. Can DISH Be a Marker for Greater Social Stratification: Jericho’s Early Bronze IV and Tell Atchana, Alalakh
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Shafiq, Rula, Eerkens, Jelmer, Series Editor, Çakırlar, Canan, Editorial Board Member, Iizuka, Fumie, Editorial Board Member, Seetah, Krish, Editorial Board Member, Sugranes, Nuria, Editorial Board Member, Tushingham, Shannon, Editorial Board Member, Wilson, Chris, Editorial Board Member, Ben-Yosef, Erez, editor, and Jones, Ian W. N., editor
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- 2023
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10. Axial Spondyloarthritis
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Baraliakos, Xenofon, McGonagle, Dennis, Braun, Jürgen, and Stone, John H., editor
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- 2023
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11. Transoral Endoscopic Resection of High Cervical Osteophytes
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Sanromán Álvarez, Pablo, González Vargas, Pedro Miguel, de la Lama Zaragoza, Adolfo Ramón, Conde Alonso, Cesáreo Miguel, and Lui, Tun Hing, editor
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- 2023
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12. Rigid spine injuries – A comprehensive review on diagnostic and therapeutic challenges
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Raymond Osayamen Schaefer, Niklas Rutsch, Klaus J. Schnake, Mohamed M. Aly, Gaston Camino-Willhuber, Martin Holas, Ulrich Spiegl, Sander Muijs, Christoph E. Albers, and Sebastian F. Bigdon
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Spine trauma ,Stiff spine ,Surgical complications ,Ankylosing spondylitis ,DISH ,Spine surgery ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Injuries to the rigid spine have a distinguished position in the broad spectrum of spinal injuries due to altered biomechanical properties. The rigid spine is more prone to fractures. Two ossification bone disorders that are of particular interest are Ankylosing Spondylitis (AS) and Diffuse Idiopathic Skeletal Hyperostosis (DISH).DISH is a non-inflammatory condition that leads to an anterolateral ossification of the spine.AS on the other hand is a chronic inflammatory disease that leads to cortical bone erosions and spinal ossifications. Both diseases gradually induce stiffening of the spine.The prevalence of DISH is age-related and is therefore higher in the older population. Although the prevalence of AS is not age-related the occurrence of spinal ossification is higher with increasing age. This association with age and the aging demographics in industrialized nations illustrate the need for medical professionals to be adequately informed and prepared.The aim of this narrating review is to give an overview on the diagnostic and therapeutic measures of the ankylosed spine.Because of highly unstable fracture configurations, injuries to the rigid spine are highly susceptible to neurological deficits. Diagnosing a fracture of the ankylosed spine on plain radiographs can be challenging. Moreover, since 8% of patients with ankylosing spine disorders (ASD) have multiple non-contagious fractures, a CT scan of the entire spine is highly recommended as the primary diagnostic tool.There are no consensus-based guidelines for the treatment of spinal fractures in ASD. The presence of neurological deficit or unstable fractures are absolute indications for surgical intervention. If conservative therapy is chosen, patients should be monitored closely to ensure that secondary neurologic deterioration does not occur. For the fractures that have to be treated surgically, stabilization of at least three segments above and below the fracture zone is recommended. These fractures mostly are treated via the posterior approach.Patients with AS or DISH share a significant risk for complications after a traumatic spine injury. The most frequent complications for patients with thoracolumbar burst fractures are respiratory failure, pseudoarthrosis, pneumonia, and implant failure.
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- 2024
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13. Anterior cervical osteotomy of diffuse idiopathic skeletal hyperostosis lesions with computer‐assisted navigation surgery: A case report
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Fedan Avrumova, Samuel N. Goldman, Franziska Altorfer, Gregory K. Paschal, and Darren R. Lebl
- Subjects
computer‐assisted navigation ,DISH ,dysphagia ,orthopedics ,osteotomy ,Medicine ,Medicine (General) ,R5-920 - Abstract
Key Clinical Message Diffuse idiopathic skeletal hyperostosis (DISH) involves spine ligament ossification. Computer‐assisted navigation (CAN) effectively aids complex surgeries, such as anterior cervical osteotomy, to alleviate progressive DISH‐related dysphagia. Abstract We describe a 68‐year‐old man with sudden onset dysphagia to both solids and liquids. Radiographic Imaging revealed DISH lesions from C2 down to the thoracic spine. The patient was successfully treated with CAN anterior osteotomy and resection of DISH lesions from C3–C6 and had complete symptom relief within 2 weeks post‐operatively.
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- 2024
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14. The Diffuse Idiopathic Skeletal Hyperostosis (DISH): A Literature Review on the Rehabilitation Treatment.
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Oliva, Francesco, Agnes, Maria Nicolina, Strollo, Fabio, Danieli, Roberta, and Maffulli, Nicola
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MUSCULOSKELETAL system diseases , *ONLINE information services , *MEDICAL databases , *OBESITY , *EXOSTOSIS , *PAIN , *SYSTEMATIC reviews , *PHYSICAL therapy , *TREATMENT effectiveness , *TYPE 2 diabetes , *MEDICAL protocols , *MANIPULATION therapy , *DESCRIPTIVE statistics , *MEDLINE , *SPINAL osteophytosis , *EXERCISE therapy , *SYMPTOMS - Abstract
Introduction. The diffuse idiopathic skeletal hyperostosis (DISH), also known as Forestier-Rotès-Querol disease, is a systemic pathology characterized by the diffuse ossification of the ligaments of the spinal column. It can be linked to several metabolic disorders, such as obesity and type II diabetes, and its prevalence among the elderly population is high. DISH may be asymptomatic and only acknowledged in the imaging, or it can be associated to serious clinical conditions like stiffness, pain and reduced spine mobility. At the moment, specific guidelines for the treatment of the DISH do not exist. This article aims to analyze the available literature concerning the rehabilitation treatment in patients affected by DISH. Materials and methods. Until July 2023, PubMed, PEDro, Scopus and Google Scholar were accessed, with no time constraints. Results. The literature available is poor, but the authors of the selected studies suggest programs based on therapeutic exercise, manual therapy, postural education, instrumental physical therapy. The discrepancy between the results obtained in case report and in RCT and cohort study, may express the need of a personalized treatment, since the characteristic of the pathology are variable depending on the localization of the hyperostosis. The rehabilitation strategies just proposed may be investigated in order to create a therapeutic path for DISH patients. Conclusions. Patients affected by DISH may cope with conditions of severe disability, caused by stiffness, pain, respiratory and dysphagic symptoms. The physiotherapy program should be based on stretching and mobility exercises to avoid pain and stiffness. This can be seen as the starting point, so that in the future this pathology might be more researched and easily diagnosed, in order to create useful guidelines and to better manage this less-known clinical condition. [ABSTRACT FROM AUTHOR]
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- 2023
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15. Inflammation and Infection: Diffuse Idiopathic Skeletal Hyperostosis (DISH)
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Van den Wyngaert, Tim, Gnanasegaran, Gopinath, Section editor, Van den Wyngaert, Tim, editor, Gnanasegaran, Gopinath, editor, and Strobel, Klaus, editor
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- 2023
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16. Musculoskeletal manifestations in type-2 diabetic patients attending a tertiary care hospital in a North-Eastern city of India—A cross-sectional observational study
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Swapan Sarkar, Bidhan Goswami, Bitan Sengupta, Shauli Sengupta, and Bhaskar Bhattacharjee
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diabetes mellitus ,dish ,musculoskeletal manifestations ,north–east india ,Medicine - Abstract
Background: Musculoskeletal manifestations of diabetes are common and not life threatening, but these are an important cause of morbidity, pain and disability among diabetic patients. In 2004, the National Health Interview Survey determined that 58% of diabetic patients would have musculoskeletal functional disability. This study was designed to estimate the proportion of musculoskeletal manifestations among Type 2 diabetic patients attending a tertiary care hospital in Tripura and also to determine the association of various musculoskeletal manifestations with glycaemic status, body mass index and duration of diabetes mellitus. Methods: This hospital-based cross-sectional study was carried out in a tertiary care hospital in a northeastern state of India from December 2020 to November 2021. All the diabetic patients attending diabetes nutrition clinic of a tertiary care hospital for a period of one year were considered for this study. Diagnosis of musculoskeletal disorder was made based on history, physical examination, laboratory test and imaging test. Quantitative data were expressed as mean and standard deviation. Descriptive data was expressed in percentages and frequencies using charts and tables. Chi-square test was applied to explore any association between variables. Ethical approval for the study was obtained from the institutional ethics committee. Results: Out of four hundred and forty-two diabetic cases and two hundred and thirty-four (52.9%) patients were found with musculoskeletal manifestations, 55% of which belong to 45–59 age group. Conclusion: Physicians treating diabetic patients should be encouraged for regular examination for musculoskeletal complaints. Early diagnosis will facilitate appropriate treatment and thus prevents further complications.
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- 2023
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17. A case series of synostosis/blocks observed in Indian human vertebra: Clinical and developmental perspective
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Mouna Subbaramaiah, R Archana, and S R Jagannatha
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blocked vertebrae ,dish ,spinal fusion ,vertebral synostosis ,Human anatomy ,QM1-695 - Abstract
Not just anatomists but also clinicians from a variety of disciplines, including orthopedic doctors, surgeons, neurologists, and neurosurgeons, are interested in vertebral abnormalities. Numerous morphological anomalies, such as spinal synostosis, occipitalization, sacralization, and lumbarization, as well as the absence of the posterior vertebral arch, have been reported. Sequentially fused vertebral segments might result in spinal fusion, synostosis of the vertebrae, or blocked vertebrae. Movement limitations, early degenerative changes, and accompanying neurological abnormalities may all be brought on by the block vertebrae. The fusion may be whole or partial, acquired, or congenital. The cervical, lumbar, and thoracic vertebral levels are the most frequently affected by vertebral fusion, whether it is congenital or acquired. A systemic disorder, known as idiopathic diffuse idiopathic skeletal hyperostosis (DISH), is defined by distinctive ossification patterns that can run over at least three more vertebral levels or four successive vertebrae on their anterolateral aspect. Here, we present a series of spinal synostosis at various levels that were identified in museum specimens from our institution and that were associated with the clinical and developmental importance.
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- 2023
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18. Solar Dish Systems
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Coventry, Joe, Alexopoulos, Spiros, Section editor, Kalogirou, Soteris, Section editor, Meyers, Robert A., Editor-in-Chief, Alexopoulos, Spiros, editor, and Kalogirou, Soteris A., editor
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- 2022
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19. Musculoskeletal Disorders of Acromegaly
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Feffer, Jill B., Poretsky, Leonid, Series Editor, Blevins Jr., Lewis S., editor, and Aghi, Manish K., editor
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- 2022
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20. Thermal Performance Comparison of Various Concentrating Solar Water Heating Systems
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Chaabane, Monia, Mhiri, Hatem, Bournot, Philippe, Cavas-Martínez, Francisco, Series Editor, Chaari, Fakher, Series Editor, di Mare, Francesca, Series Editor, Gherardini, Francesco, Series Editor, Haddar, Mohamed, Series Editor, Ivanov, Vitalii, Series Editor, Kwon, Young W., Series Editor, Trojanowska, Justyna, Series Editor, Ben Amar, Mounir, editor, Bouguecha, Anas, editor, Ghorbel, Elhem, editor, and El Mahi, Aberrahim, editor
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- 2022
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21. A case of SAPHO syndrome: a DISH of radiological features to be considered
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Fakhreddin Sabooniha
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SAPHO syndrome ,Palmoplantar pustulosis ,Psoriasis ,DISH ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background The acronym SAPHO stands for synovitis, acne, pustulosis, hyperostosis, and osteitis. It is a rare heterogenous disease with unknown etiology and a chronic relapsing and remitting course1. Its skin and osteoarticular manifestations including palmoplantar pustulosis (PPP) and synovitis may be transient which further complicate the diagnosis. So, awareness about all features of the syndrome throughout the time seems mandatory for correct diagnosis and avoidance of unnecessary procedures. Case presentation. A case of SAPHO syndrome being reported in a middle-aged man who presented with bilateral PPP and exacerbation of back pain which developed shortly after covid-19 vaccine injection with a history of more than 20 years of inflammatory thoracic back pain and psoriasis vulgaris who initially had been worked up for metastatic bony lesions based on radiologic studies, irrespective of his skin lesions. The patient had good response to alendronate 70 mg weekly and celecoxib 200 mg BID without aggravation of existing skin lesions or new psoriatic lesions. Conclusion This case report aims to inform rheumatologists and radiologists about various radiologic and dermatologic manifestations of SAPHO syndrome with emphasizing on taking into consideration of past and present skin lesions in the interpretation of the radiologic signs in order to prevent irrelevant procedures or hazardous imaging and to urge rheumatology societies to set up a SAPHO registry for future randomized controlled trials. Suggestion of PPP responsiveness to NSAIDs as a new potential diagnostic tool for SAPHO diagnosis is another goal. It also aims to point out the possible coexistence of SAPHO and SpA or DISH syndrome.
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- 2022
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22. Diffuse idiopathic skeletal hyperostosis as a cause for dysphagia in a patient with ankylosing spondylitis.
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Schwarz, Caroline, Schwarz, Michael, Schmidbauer, Victor, Kainberger, Franz, Milos, Ruxandra-Iulia, Langenberger, Herbert, Gessl, Irina, Funk, Georg, and Gschwantler, Michael
- Abstract
Summary: Background: Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by ankylosing spinal alterations which are often asymptomatic but may typically cause back pain and spinal stiffness. Presence of DISH may complicate spinal trauma and lead to unstable fractures requiring surgical intervention. Treatment options include physical activity, symptomatic treatment, local heat application, and optimization of metabolic comorbidities. Case: A multimorbid older patient was admitted to the gastroenterological ward for the investigation of progressive dysphagia and weight loss. Gastroscopy revealed a dorsal impression of the esophagus at 25 cm from the incisor. Clinical work-up including computed tomography (CT) and magnetic resonance imaging (MRI) ruled out malignancy but showed ankylosing spondylophytes and non-recent fractures of vertebrae C5–C7, compatible with DISH of the cervicothoracic spine as a cause for the esophageal impression. Notably, imaging diagnostics showed ankylosing spine alterations extending to the lumbar spine and both sacroiliac joints, suggestive of ankylosing spondylitis (AS). Typical imaging characteristics, a history of psoriasis, and positive HLA*B27 status supported the diagnosis of underlying AS in this patient with dysphagia as an unusual primary symptom of DISH. Additionally, pulmonary alterations compatible with a usual interstitial pneumonia (UIP)-like pattern were seen on lung CT. Conclusion: Overlaps among AS, DISH and pulmonary abnormalities including UIP have been described previously; however, they represent unexpected findings in this older patient. This case underlines the importance of interdisciplinary collaboration and consideration of DISH as a differential diagnosis in patients with atypical symptoms. [ABSTRACT FROM AUTHOR]
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- 2023
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23. A radiological study of the natural history of diffuse idiopathic skeletal hyperostosis (DISH): a story of incomplete fusion.
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Phang, See Yung, Barrett, Christopher, and Purcell, Margaret
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Abstract
Introduction: DISH is an ankylosing disease, when fractured can be challenging to manage. A retrospective radiological study was conducted to evaluate the natural history and radiological characteristics of DISH on Computed tomography (CT).Methods: Paired CT scans with DISH that are separated at least two years apart were used to perform the following radiological measurements: Degree of disc space fusion, Osteophyte and vertebral body linear attenuation coefficients (LAC), and Osteophyte axial area size and location.Results: 164 patients were analysed with a mean duration of 4.49 years between scans. 38.14% (442/1159) of disc spaces had at least partial calcification. Most osteophytes were right sided before becoming more circumferential over time. The average fusion score was 54.17. Most of the changes in fusion occurred in the upper and lower thoracic regions. The thoracic region when compared to the lumbar region had a greater proportion of its disc spaced being fully fused. Disc level osteophyte areas were larger than Body level osteophytes. Disc osteophytes size growth rate drops over time from 10.89mm2/year in Stage 1 to 3.56mm2/year in Stage 3. Stage 3 disc spaces (−11.01HU/year) was also found to have had a reduction in their LAC over time when compared to Stage 1 disc spaces (17.04HU/year). This change in osteophyte LAC was not mirrored in the change in vertebral body LAC. We predict that the age of onset and complete thoracolumbar ankylosis of DISH to be 17.96 years and 100.59 years, respectively.Conclusion: DISH ankylosis of the spine a slow process that starts in the mid to lower thoracic region before extending cranially and caudally. After the bridging osteophyte has fully formed, remodelling of the osteophyte occurs. [ABSTRACT FROM AUTHOR]- Published
- 2023
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24. Subjects with diffuse idiopathic skeletal hyperostosis have an increased burden of coronary artery disease: An evaluation in the COPDGene cohort
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Oudkerk, Sytse F, Mohamed Hoesein, Firdaus AA, PThM Mali, Willem, Öner, F Cumhur, Verlaan, Jorrit-Jan, de Jong, Pim A, Kinney, Gregory L, Hokanson, John, Lynch, David, Silverman, Edwin K, Budoff, Matthew J, and Regan, Elizabeth A
- Subjects
Biomedical and Clinical Sciences ,Cardiovascular Medicine and Haematology ,Clinical Sciences ,Heart Disease - Coronary Heart Disease ,Prevention ,Clinical Research ,Cardiovascular ,Atherosclerosis ,Heart Disease ,Detection ,screening and diagnosis ,4.1 Discovery and preclinical testing of markers and technologies ,Aged ,Aged ,80 and over ,Coronary Artery Disease ,Female ,Follow-Up Studies ,Humans ,Hyperostosis ,Incidence ,Male ,Middle Aged ,Multidetector Computed Tomography ,Retrospective Studies ,Risk Assessment ,Risk Factors ,United States ,Vascular Calcification ,Calciumscore ,CT ,DISH ,Coronary artery disease ,Agatson score ,Cardiorespiratory Medicine and Haematology ,Cardiovascular System & Hematology ,Cardiovascular medicine and haematology ,Clinical sciences - Abstract
Background and aimsDiffuse idiopathic skeletal hyperostosis (DISH) is a common incidental finding on medical imaging and often thought to be benign. Our objective was to investigate whether DISH is associated with coronary artery disease as measured with the coronary artery calcification (CAC) score in a large cohort of current and former smokers.MethodsIn a subset of subjects from the COPDGene study, DISH was scored by a minimum of two independent readers if there were four adjacent levels of flowing osteophytes and a third reader adjudicated discrepancies. CAC was calculated using a modified Agatston method. Associations of DISH with the presence and extent of CAC were analyzed with and without adjustment for COPD and known atherosclerotic risk factors, including age, sex, race, diabetes, hypertension, high cholesterol, body mass index and smoking.ResultsDISH was present in 361 subjects (13.2%) from a total group of 2728. Median (interquartile range) Agatston was 81 (0-329) in DISH subjects compared to 0 (0-94 in subjects without DISH (p
- Published
- 2019
25. Musculoskeletal manifestations in type-2 diabetic patients attending a tertiary care hospital in a North-Eastern city of India—A cross-sectional observational study.
- Author
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Sarkar, Swapan, Goswami, Bidhan, Sengupta, Bitan, Sengupta, Shauli, and Bhattacharjee, Bhaskar
- Subjects
- *
PEOPLE with diabetes , *TERTIARY care , *URBAN hospitals , *CROSS-sectional method , *SCIENTIFIC observation - Abstract
Background: Musculoskeletal manifestations of diabetes are common and not life threatening, but these are an important cause of morbidity, pain and disability among diabetic patients. In 2004, the National Health Interview Survey determined that 58% of diabetic patients would have musculoskeletal functional disability. This study was designed to estimate the proportion of musculoskeletal manifestations among Type 2 diabetic patients attending a tertiary care hospital in Tripura and also to determine the association of various musculoskeletal manifestations with glycaemic status, body mass index and duration of diabetes mellitus. Methods: This hospital-based cross-sectional study was carried out in a tertiary care hospital in a northeastern state of India from December 2020 to November 2021. All the diabetic patients attending diabetes nutrition clinic of a tertiary care hospital for a period of one year were considered for this study. Diagnosis of musculoskeletal disorder was made based on history, physical examination, laboratory test and imaging test. Quantitative data were expressed as mean and standard deviation. Descriptive data was expressed in percentages and frequencies using charts and tables. Chi-square test was applied to explore any association between variables. Ethical approval for the study was obtained from the institutional ethics committee. Results: Out of four hundred and forty-two diabetic cases and two hundred and thirty-four (52.9%) patients were found with musculoskeletal manifestations, 55% of which belong to 45–59 age group. Conclusion: Physicians treating diabetic patients should be encouraged for regular examination for musculoskeletal complaints. Early diagnosis will facilitate appropriate treatment and thus prevents further complications. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
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26. Imaging Characteristics of Diffuse Idiopathic Skeletal Hyperostosis: More Than Just Spinal Bony Bridges.
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Eshed, Iris
- Subjects
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EXOSTOSIS , *BONE growth , *SACROILIAC joint , *SPINE , *SKELETON - Abstract
Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic condition characterized by new bone formation and enthesopathies of the axial and peripheral skeleton. The pathogenesis of DISH is not well understood, and it is currently considered a non-inflammatory condition with an underlying metabolic derangement. Currently, DISH diagnosis relies on the Resnick and Niwayama criteria, which encompass end-stage disease with an already ankylotic spine. Imaging characterization of the axial and peripheral skeleton in DISH subjects may potentially help identify earlier diagnostic criteria and provide further data for deciphering the general pathogenesis of DISH and new bone formation. In the current review, we aim to summarize and characterize axial and peripheral imaging findings of the skeleton related to DISH, along with their clinical and pathogenetic relevance. [ABSTRACT FROM AUTHOR]
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- 2023
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27. Preferencias y disponibilidad para pagar por degustar el platillo chile en nogada, en San Nicolás de Los Ranchos y San Andrés Calpan.
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Pano-Jiménez, Alejandra, Jaramillo-Villanueva, José Luis, Núñez-Tovar, Ramón, Martínez-Domínguez, Marlen, and Carranza-Cerda, Ignacio
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WILLINGNESS to pay , *CONSUMER preferences , *COVID-19 pandemic , *STATE fairs , *GASTRONOMY , *SOCIOECONOMIC factors , *PRICES , *FOOD tourism - Abstract
Objectives: The goal of this work was to know the preferences of visitors to the chile in nogada fairs in San Andrés Calpan and San Nicolas de los Ranchos municipalities and to estimate the Willingness to Pay (WTP). Methodology: The field work to get the data, was carried out July to September 2021 during the days of the chile in nogada fairs. The data was obtained by survey and interviews. Results: The price of the dish was between $150 to $200. 72.8% WTP declared an overprice for consuming the dish with ingredients from the region. Limitations: Due to logistical problems due to the covid pandemic, it was not possible to expand the exhibition to other chile in nogada fairs in the state of Puebla. Conclusions: Consumers of the chile in nogada dish know the ingredients and their origin and showed WTP for consuming it. Socioeconomic factors affect the purchase decision; These could be used to design a promotional strategy for the dish. [ABSTRACT FROM AUTHOR]
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- 2023
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28. Impacts to Human Health and Ecosystems
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Soeder, Daniel J. and Soeder, Daniel J.
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- 2021
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29. Not so Mutually Exclusive Diseases: A Case of Co-occurrence of Inflammatory Spondyloarthritis and Diffuse Skeletal Hyperostosis in a Young Patient
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Filipa Taborda, Duarte André Ferreira, Teresa Mendonça, and Fátima Farinha
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diffuse idiopathic skeletal hyperostosis ,dish ,ankylosing spondylitis ,spondyloarthritis ,spa ,Medicine - Abstract
Diffuse idiopathic skeletal hyperostosis (DISH) and axial spondyloarthritis (axial SpA) are differential diagnoses of lower back pain. While the latter is considered to be an inflammatory disease, DISH is thought to be a metabolic condition. The authors report a case of a 34-year-old man who presented with a one-year history of axial lower back pain associated to migratory polyarthritis, buttock and heel pain. Imaging revealed contiguous calcification of the anterior longitudinal ligament of the cervical segment, meeting major criteria for DISH. However, he also exhibited signs of bilateral sacroiliitis highly suggestive of axial SpA for which he initiated biological therapy.
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- 2023
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30. A case of SAPHO syndrome: a DISH of radiological features to be considered.
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Sabooniha, Fakhreddin
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BONE diseases ,EXOSTOSIS ,NONSTEROIDAL anti-inflammatory agents ,DEVELOPMENTAL disabilities ,RHEUMATOLOGISTS ,RADIONUCLIDE imaging ,SPINAL osteophytosis - Abstract
Background: The acronym SAPHO stands for synovitis, acne, pustulosis, hyperostosis, and osteitis. It is a rare heterogenous disease with unknown etiology and a chronic relapsing and remitting course
1 . Its skin and osteoarticular manifestations including palmoplantar pustulosis (PPP) and synovitis may be transient which further complicate the diagnosis. So, awareness about all features of the syndrome throughout the time seems mandatory for correct diagnosis and avoidance of unnecessary procedures. Case presentation. A case of SAPHO syndrome being reported in a middle-aged man who presented with bilateral PPP and exacerbation of back pain which developed shortly after covid-19 vaccine injection with a history of more than 20 years of inflammatory thoracic back pain and psoriasis vulgaris who initially had been worked up for metastatic bony lesions based on radiologic studies, irrespective of his skin lesions. The patient had good response to alendronate 70 mg weekly and celecoxib 200 mg BID without aggravation of existing skin lesions or new psoriatic lesions. Conclusion: This case report aims to inform rheumatologists and radiologists about various radiologic and dermatologic manifestations of SAPHO syndrome with emphasizing on taking into consideration of past and present skin lesions in the interpretation of the radiologic signs in order to prevent irrelevant procedures or hazardous imaging and to urge rheumatology societies to set up a SAPHO registry for future randomized controlled trials. Suggestion of PPP responsiveness to NSAIDs as a new potential diagnostic tool for SAPHO diagnosis is another goal. It also aims to point out the possible coexistence of SAPHO and SpA or DISH syndrome. [ABSTRACT FROM AUTHOR]- Published
- 2022
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31. Osteophytes' position in subjects with DISH and right-sided aorta: verification of the 'aortic pulsation protective effect' theory.
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Gliner-Ron, Masha, Bercovich, Eyal, Herman, Amir, Lidar, Merav, Militianu, Daniela, and Eshed, Iris
- Subjects
- *
METAPLASTIC ossification , *EXOSTOSIS , *CHEST X rays , *THORACIC aorta , *CONGENITAL heart disease , *INTERVERTEBRAL disk , *DESCRIPTIVE statistics , *COMPUTED tomography , *THORACIC vertebrae , *SPINAL osteophytosis , *LONGITUDINAL method - Abstract
Objectives To validate in a large cohort with right-sided aorta the theory that thoracic right-sided flowing osteophytes in DISH results from a 'protective' effect of the pulsating descending left-sided thoracic aorta. Methods Chest CTs of patients with DISH and right-sided aorta and controls with DISH and left-sided aorta were evaluated and compared on each intervertebral space (IS) for the location of the aorta (right, left, centre) and the location of the osteophyte relative to the aorta (contralateral, ipsilateral, bilateral). Results The study and control cohorts included 31 and 35 subjects, respectively (male 22/9 and female 27/8; median age 64.8/65.3 years; P = 0.86). Osteophytes contralateral to the aorta's location were recorded in the majority of ISs in both the study and control groups (47% and 60%, respectively; P > 0.05), while ipsilateral osteophytes were recorded in 6.9% and 7.7%, respectively (P = 0.002). Bilateral osteophytes located to the right and the left of the aorta were significantly more prevalent in the study group compared with the controls (17.2% and 5.4%, respectively; P = 0.04). Conclusions Aortic pulsation plays an important role in inhibiting the development of osteophytes and results in the majority of contralateral osteophytes on both right-sided and left-sided aortas. However, since both ipsilateral and bilateral osteophytes were not at all rare in both groups, other parameters, which are yet to be established, probably contribute to the location of osteophytes. [ABSTRACT FROM AUTHOR]
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- 2022
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32. Surgical Treatment of Diffuse Idiopathic Skeletal Hyperostosis (DISH) Involving the Cervical Spine: Technical Nuances and Outcome of a Multicenter Experience.
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Lofrese, Giorgio, Scerrati, Alba, Balsano, Massimo, Bassani, Roberto, Cappuccio, Michele, Cavallo, Michele A., Cofano, Fabio, Cultrera, Francesco, De Iure, Federico, Biase, Francesco Di, Donati, Roberto, Garbossa, Diego, Menegatti, Marta, Olivi, Alessandro, Palandri, Giorgio, Raco, Antonino, Ricciardi, Luca, Spena, Giannantonio, Tosatto, Luigino, and Visani, Jacopo
- Subjects
EXOSTOSIS ,SPINAL injuries ,TREATMENT effectiveness ,SURGICAL decompression ,DEGLUTITION disorders ,NASOENTERAL tubes ,FOLLOW-up studies (Medicine) - Abstract
Study Design: Retrospective multicenter. Objectives: diffuse idiopathic skeletal hyperostosis (DISH) involving the cervical spine is a rare condition determining disabling aero-digestive symptoms. We analyzed impact of preoperative settings and intraoperative techniques on outcome of patients undergoing surgery for DISH. Methods: Patients with DISH needing for anterior cervical osteophytectomy were collected. Swallow studies and endoscopy supported imaging in targeting bone decompression. Patients characteristics, clinico-radiological presentation, outcome and surgical strategies were recorded. Impact on clinical outcome of duration and time to surgery and different surgical techniques was evaluated through ANOVA. Results: 24 patients underwent surgery. No correlation was noted between specific spinal levels affected by DISH and severity of pre-operative dysphagia. A trend toward a full clinical improvement was noted preferring the chisel (P = 0.12) to the burr (P = 0.65), and whenever C2-C3 was decompressed, whether hyperostosis included that level (P = 0.15). Use of curved chisel reduced the surgical times (P = 0.02) and, together with the nasogastric tube, the risk of complications, while bone removal involving 3 levels or more (P = 0.04) and shorter waiting times for surgery (P < 0.001) positively influenced a complete swallowing recovery. Early decompressions were preferred, resulting in 66.6% of patients reporting disappearance of symptoms within 7 days. One and two recurrences respectively at clinical and radiological follow-up were registered 18-30 months after surgery. Conclusion: The "age of DISH" counts more than patients' age with timeliness of decompression being crucial in determining clinical outcome even with a preoperative mild dysphagia. Targeted bone resections could be reasonable in elderly patients, while in younger ones more extended decompressions should be preferred. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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33. Prevalence and characteristics of diffuse idiopathic skeletal hyperostosis (DISH) in Italy.
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Ciaffi, Jacopo, Borlandelli, Elena, Visani, Gaia, Facchini, Giancarlo, Miceli, Marco, Ruscitti, Piero, Cipriani, Paola, Giacomelli, Roberto, and Ursini, Francesco
- Abstract
Purpose: Diffuse idiopathic skeletal hyperostosis (DISH) is a benign condition characterized by ossification of the spine and prominent enthesopathies. Highly heterogeneous epidemiological figures have been reported in the literature, while in Italy the largest study has been conducted in 1992. The aim of our research is to contribute updated information about prevalence of DISH in Italy and to describe the clinical and radiographic characteristics associated with the disorder. Material and methods: A retrospective review of lumbosacral spine, thoracic spine and pelvis radiographs was performed. Consecutive patients visiting the emergency department of our Institution over 3 years were enrolled. Presence of DISH was evaluated applying the Resnick and Niwayama criteria. Clinical and radiological features were also assessed. Results: We included 1012 individuals (60.6% women), and DISH was present in 130 cases. The overall prevalence of DISH was 12.8% (95% CI 10.8–15.1), with higher figures in the male sample (16.8%) than in females (10.3%). In binary logistic regression adjusted for age, BMI (OR 1.50, p < 0.001) diabetes (OR 1.85, p = 0.003), hypertension (OR 2.04, p = 0.007) ischiopubic enthesopathy (OR 7.08, p < 0.001), iliac crest enthesopathy (OR 4.63, p < 0.001) and greater trochanter enthesopathy (OR 3.51, p < 0.001), were significantly associated with the condition. Conclusion: The prevalence of DISH observed in our study is consistent with previous literature, and we confirm that the disorder is more frequently retrieved in men and that it is associated with the presence of metabolic disorders and pelvic enthesopathy. Knowledge about the epidemiology and characteristics of DISH is needed to properly identify the condition. [ABSTRACT FROM AUTHOR]
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- 2022
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34. Hyperextensionsverletzungen der ankylosierten Wirbelsäule - Einfluss der Frakturmorphologie auf die Versorgungsstrategie
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Heintel, T, Knauer, M, Jovic, S, Meffert, R, Heintel, T, Knauer, M, Jovic, S, and Meffert, R
- Published
- 2024
35. Concomitant DISH and cervical OPLL: a U.S. database study of clinical prevalence, surgical intervention, patient characteristics, and post-operative complications.
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Litvak AL, Zhang DM, Seidel H, Benson D, Lee CS, Lee MJ, and El Dafrawy MH
- Abstract
Background: Concomitant diffuse idiopathic skeletal hyperostosis (DISH) and cervical ossification of the posterior longitudinal ligament (cOPLL) is primarily investigated in radiographic studies of East Asian populations. This study aimed to determine clinical prevalence of concomitant DISH/cOPLL in a large U.S. sample and to compare characteristics and complications in cOPLL patients with and without concomitant DISH who were surgically treated., Methods: A retrospective database study was performed using PearlDiver. Billing codes identified cOPLL patients with and without concomitant DISH during 2010-2022. Annual prevalence was calculated. Patients undergoing cervical/thoracic spine decompression with/without fusion were included. Bivariate analyses compared patient characteristics, 1-year reoperation, and cohort-matched 90-day complications., Results: 681 cOPLL patients had concomitant DISH and 28,395 did not. Prevalence of DISH in patients with cOPLL was 1.4%. cOPLL patients with DISH underwent surgery more frequently than those without (30.2% vs. 21.7%; p<0.0001) via posterior approach (68.0% vs. 42.1%; p<0.0001). cOPLL patients with DISH undergoing surgery were more frequently male (71.0% vs. 51.6%; p<0.0001) with higher proportion of metabolic syndrome (61.4% vs. 37.9%; p<0.0001). Compared to cOPLL patients without DISH, cOPLL patients with DISH had similar 1-year reoperation (8.3% vs. 9.6%; p=0.61) and post-match 90-day complications (17.8% vs. 14.2%; p=0.31), yet higher overall neurological injury (14.7% vs. 6.9%; p=0.0047) amid infrequent procedure-related neurological injury (2.3% vs. 0.6%; p=0.08)., Conclusion: Clinical prevalence of DISH in patients with cOPLL in the U.S. is low, yet cOPLL patients with concomitant DISH underwent surgery more frequently compared to those without. Despite higher comorbidity burden, cOPLL patients with DISH may have similar short-term post-surgical risk to cOPLL patients without DISH. However, higher non-procedural neurological injury in cOPLL patients with DISH may indicate insidious or delayed disease sequelae., (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.)
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- 2024
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36. OPLL: Disease Entity, Prevalence, Literature Research, and Growth
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Fujimori, Takahito, Okawa, Atsushi, editor, Matsumoto, Morio, editor, Iwasaki, Motoki, editor, and Kawaguchi, Yoshiharu, editor
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- 2020
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37. Introduction to Spine Imaging and Sacroiliac Imaging
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Ozen, Merve, Kocak, Mehmet, Basu, Anupam, Katz, Robert S., editor, and Basu, Anupam, editor
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- 2020
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38. DISHphagia – A Riddle Unwrapped a Clinical Case with Literature Review
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Valkov H., Kovacheva-Slavova M., Lyutakov I., Angelov T., Getsov P., Vladimirov B., and Penchev P.
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diffuse idiopathic skeletal hyperostosis ,dish ,dysphagia ,dishphagia ,osteophytes ,Medicine - Abstract
Diffuse idiopathic skeletal hyperostosis (DISH) is a common but underdiagnosed systemic skeletal disease. It is characterized by calcifications affecting mainly the spinal anterior longitudinal ligament. In the majority of cases, the patients are asymptomatic, but cervical osteophytes can sometimes cause hoarseness, dysphagia (DISHphagia) and even dyspnea.
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- 2021
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39. Diffuse idiopathic skeletal hyperostosis of the cervical spine causing dysphagia and airway obstruction: an updated systematic review.
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Harlianto, Netanja I., Kuperus, Jonneke S., Mohamed Hoesein, Firdaus A.A., de Jong, Pim A., de Ru, Jacob A., Öner, F. Cumhur, and Verlaan, Jorrit-Jan
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- *
SPINAL osteophytosis complications , *METAPLASTIC ossification , *CERVICAL vertebrae , *EXOSTOSIS , *SYSTEMATIC reviews , *DEGLUTITION disorders , *RESPIRATORY obstructions , *SPINAL osteophytosis - Abstract
Background and Context: Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by growing ossifications of spinal entheses and tendons, which may cause trachea and esophagus compression when located anteriorly in the cervical spine.Purpose: Our previous systematic review on the epidemiological and clinical knowledge of dysphagia and airway obstruction caused by cervical DISH was updated, with a focus on (surgical) treatment and outcomes.Study Design: A systematic review of the literature was performed.Methods: Publications in Medline and EMBASE from July 2010 to June 2021 were searched. Two investigators performed data extraction and study specific quality assessment.Results: A total of 138 articles (112 case reports and 26 case series) were included, describing 419 patients with dysphagia and/or airway obstruction. The mean age of the patient group was 67.3 years (range: 35-91 years), and 85.4% was male. An evident increase of published cases was observed within the last decade. Surgical treatment was chosen for 66% of patients with the anterolateral approach most commonly used. The total complication rate after surgery was 22.1%, with 12.7% occurring within 1 month after intervention. Improvement of dysphagia was observed in 95.5% of operated patients. After a mean follow-up of 3.7 years (range: 0.4-9.0 years), dysphagia recurred in 12 surgically treated patients (4%), of which five patients had osteophyte regrowth.Conclusions: The number of published cases of dysphagia in patients with DISH has doubled in the last decade compared to our previous review. Yet, randomized studies or guidelines on the treatment or prevention on recurrence are lacking. Surgical treatment is effective and has low (major) complication rates. Common trends established across the cases in our study may help improve our understanding and management of dysphagia and airway obstruction in cervical DISH. [ABSTRACT FROM AUTHOR]- Published
- 2022
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40. Diffuse idiopathic skeletal hyperostosis is associated with incident stroke in patients with increased cardiovascular risk.
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Harlianto, Netanja I, Oosterhof, Nadine, Foppen, Wouter, Hol, Marjolein E, Wittenberg, Rianne, Veen, Pieternella H van der, Ginneken, Bram van, Hoesein, Firdaus A A Mohamed, Verlaan, Jorrit-Jan, Jong, Pim A de, Westerink, Jan, and UCC-SMART-Studygroup, for the
- Subjects
- *
SPINAL osteophytosis complications , *CARDIOVASCULAR diseases risk factors , *EXOSTOSIS , *CONFIDENCE intervals , *MAJOR adverse cardiovascular events , *ISCHEMIC stroke , *MYOCARDIAL infarction , *DISEASE incidence , *RISK assessment , *DESCRIPTIVE statistics , *STATISTICAL models , *SPINAL osteophytosis , *LONGITUDINAL method , *PROPORTIONAL hazards models , *DISEASE risk factors ,CARDIOVASCULAR disease related mortality - Abstract
Objectives Earlier retrospective studies have suggested a relation between DISH and cardiovascular disease, including myocardial infarction. The present study assessed the association between DISH and incidence of cardiovascular events and mortality in patients with high cardiovascular risk. Methods In this prospective cohort study, we included 4624 patients (mean age 58.4 years, 69.6% male) from the Second Manifestations of ARTerial disease cohort. The main end point was major cardiovascular events (MACE: stroke, myocardial infarction and vascular death). Secondary endpoints included all-cause mortality and separate vascular events. Cause-specific proportional hazard models were used to evaluate the risk of DISH on all outcomes, and subdistribution hazard models were used to evaluate the effect of DISH on the cumulative incidence. All models were adjusted for age, sex, body mass index, blood pressure, diabetes, non-HDL cholesterol, packyears, renal function and C-reactive protein. Results DISH was present in 435 (9.4%) patients. After a median follow-up of 8.7 (IQR 5.0–12.0) years, 864 patients had died and 728 patients developed a MACE event. DISH was associated with an increased cumulative incidence of ischaemic stroke. After adjustment in cause-specific modelling, DISH remained significantly associated with ischaemic stroke (HR 1.55; 95% CI: 1.01, 2.38), but not with MACE (HR 0.99; 95% CI: 0.79, 1.24), myocardial infarction (HR 0.88; 95% CI: 0.59, 1.31), vascular death (HR 0.94; 95% CI: 0.68, 1.27) or all-cause mortality (HR 0.94; 95% CI: 0.77, 1.16). Conclusion The presence of DISH is independently associated with an increased incidence and risk for ischaemic stroke, but not with MACE, myocardial infarction, vascular death or all-cause mortality. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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41. Percutaneous, PMMA-augmented, pedicle screw instrumentation of thoracolumbar ankylotic spine fractures
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Rina E. Buxbaum, Adi Shani, Hani Mulla, Alon Rod, and Nimrod Rahamimov
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Spine trauma ,Vertebral fracture ,Ankylosing spondylitis ,DISH ,Percutaneous spine surgery ,Spinal cord injury ,Orthopedic surgery ,RD701-811 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Introduction Fractures in the ankylotic spine may have an insidious presentation but are prone to displace with devastating consequences. The long lever arm of ankylosed spine fragments may lead to pulmonary and great vessel injury and is difficult to adequately immobilize. Conservative treatment will produce in many cases poor outcomes with high morbidity and mortality. Open surgical treatment is also fraught with technical difficulties and can lead to major blood loss and prolonged operative times. In recent years, percutaneous instrumentation of non-ankylotic spine fractures has gained popularity, producing similar outcomes to open surgery with shorter operative times and reduced blood loss and hospital length of stay. We describe our experience implementing these techniques in ankylotic spine patients. Methods We retrospectively retrieved from our hospital’s electronic health records all patients treated for thoracolumbar spine fractures between 2008 and 2015 with a diagnosis of ankylosing spondylitis (AS) or diffuse idiopathic skeletal hyperostosis (DISH). Operative and postoperative data, results, and complications were tabulated, and radiographic parameters were evaluated. Results Twenty-four patients with ankylotic spine disease underwent percutaneous augmented instrumentation between 2008 and 2015. The mean age was 76. All patients had at least one comorbidity. The mean number of ankylosed levels was 14. Mean operative time was 131 min. The average postoperative hemoglobin decrease was 1.21 gr/%, with only 4 patients requiring blood transfusion. 45.8% of the patients had postoperative medical complications. One patient (4.2%) had a superficial postoperative infection, and one patient died in hospital. The average hospital length of stay was 14.55 days. All patients retained their preoperative ASIA grades, and 3 improved one grade. All patients united their fractures without losing reduction. Conclusions PMMA-augmented percutaneous instrumentation is an attractive surgical option for this difficult patient subset, especially when compared to other available current alternatives.
- Published
- 2021
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42. Clinical presentation and burden of ENPP1 deficiency in adults.
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Seefried, Lothar
- Subjects
- *
RICKETS , *HEALTH of adults , *ARTERIAL calcification , *OSTEOPOROSIS , *EXOSTOSIS - Abstract
While the clinical consequences of severe ENPP1 deficiency leading to the rare disorders generalized arterial calcification of infancy (GACI) and autosomal recessive hypophosphatemic rickets type 2 (ARHR2) are well defined and understood, much less is known about how this evolves into adulthood and how moderate ENPP1 deficiency can first manifest in adulthood. Moreover, growing evidence substantiates an association of genetic variants in the ENPP1 gene with a wide range of further clinical manifestations including early-onset osteoporosis, osteoarthritis, and different forms of spinal ligament calcifications, i.e., diffuse idiopathic skeletal hyperostosis (DISH) and ossification of the posterior/anterior longitudinal ligament (OPLL/OALL). Furthermore, conditions with primarily extraskeletal signs and symptoms such as Cole disease, coagulopathies, and metabolic syndrome can seemingly result from ENPP1 variants. The causality and the pathophysiology behind these different clinical presentations appear complex and require further research, especially since the coincidence of these different phenotypes is rarely described and available evidence suggests that part of the aforementioned manifestations may result from ENPP1 effects beyond the catalytic activity of processing ATP to AMP and inorganic pyrophosphate (PPi). Growing awareness of the additional ENPP1 -related manifestations across the lifespan will advance our understanding of this complex condition and help to standardize diagnostic approaches and develop individually tailored treatment concepts. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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43. Acute upper airway obstruction caused by cervical osteophytes in diffuse idiopathic skeletal hyperostosis: A case report.
- Author
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Pruijn, Ineke M.J., Marres, Henri A.M., and van den Broek, Guido B.
- Abstract
The manifestation of acute upper airway obstruction, coupled with dysphagia and potential vocal cord paresis, typically raises suspicion of advanced laryngeal or pharyngeal malignancy. However, this case report illuminates an unusual systemic condition— diffuse idiopathic skeletal hyperostosis (DISH) with cervical osteophytes—that can resemble the clinical presentation of these malignancies. Two cases involving 78-year and 82-year-old males exhibiting progressive dysphagia, dysphonia, and acute upper airway obstruction due to substantial osteophytes at the C2-C4 levels are presented. Clinicians should consider DISH in the differential diagnosis of dysphagia and upper airway obstruction after ruling out laryngeal and pharyngeal malignancies. Timely recognition and appropriate management of DISH has proven effective in relieving symptoms and restoring normal swallowing and breathing, preventing acute life-saving interventions, contributing to improved patient outcomes. • Diffuse idiopathic skeletal hyperostosis (DISH) can mimic pharyngeal or laryngeal malignancies due to large cervical osteophytes. • DISH may cause dysphagia, vocal cord paralysis and acute upper airway obstruction • DISH can be treated surgically by osteophytectomy through an anterolateral cervical approach [ABSTRACT FROM AUTHOR]
- Published
- 2024
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44. An isotope signature for diffuse idiopathic skeletal hyperostosis?
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Castells Navarro, Laura, Buckberry, Jo, and Beaumont, Julia
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EXOSTOSIS , *STABLE isotopes , *COLLAGEN , *DIET , *ISOTOPIC signatures - Abstract
Objectives: Diffuse idiopathic skeletal hyperostosis (DISH) has recurrently been associated with a rich diet (high in protein and higher trophic level foods); however, very few studies have investigated this link using carbon and nitrogen (δ13C and δ15N) stable isotope analysis. This paper explores the relationship between DISH and diet in two Roman urban communities by analyzing individuals with and without DISH. Materials and methods: δ13C and δ15N analysis carried out on collagen from 33 rib samples (No DISH: 27; early DISH: 4; DISH: 2) selected from individuals buried at the Romano‐British site of Baldock (UK), 41 rib samples (No DISH: 38; early DISH: 3) from individuals from the Catalan Roman site of Santa Caterina (Barcelona, Spain). Additionally, six faunal samples from Baldock and seven from Santa Caterina were analyzed. Results: Standardized human isotope data from Santa Caterina show high δ15N probably associated to a diet combining terrestrial resources and freshwater fish. In contrast, isotope results from Baldock suggest a terrestrial‐based diet. Individuals with DISH do not show isotopic ratios indicative of rich diet and there is no correlation between stage of DISH development and δ13C and δ15N. Conclusion: The results of this study suggest that individuals with DISH followed a similar or isotopically similar diet as those individuals without DISH in Baldock and in Santa Caterina and therefore, while DISH may have been influenced by individual's dietary habits, this is not reflected in their isotopic signature. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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45. The prevalence of diffuse idiopathic skeletal hyperostosis in England and Catalonia from the Roman to the post-medieval periods.
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Castells Navarro, Laura and Buckberry, Jo
- Abstract
Evaluate the prevalence of DISH through time from the Roman to the post-Medieval period in England and Catalonia. 281 individuals from England and 247 from Catalonia were analyzed. Adult individuals with at least three well-preserved lower thoracic vertebral bodies were analyzed. DISH was assessed considering the early stages of development. Diachronic and geographical dietary shifts were investigated using reported light isotope data, archaeological reports and historical documentation. Males and older individuals showed consistently higher prevalence of DISH, however, only the English sample showed a significant difference between males and females in the prevalence of DISH. No significant difference was found in the prevalence of DISH though time (from Roman to post medieval periods) nor across regions (England and Catalonia). The development of DISH is probably influenced by a combination of factors including increasing age and sex. This is the first exhaustive analysis of DISH in ancient Catalan populations and the first that considers the early stages of DISH. Reduced sample size, particularly in post-medieval samples, as a result of the available excavated samples and the inclusion criteria adopted. Include rural, religious and high-status samples in the analysis of DISH. Re-assess the prevalence of DISH in post-medieval populations. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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46. A case of cervical OPLL and DISH mimicking stroke.
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Prabhu, Rudra Mangesh, Rathod, Tushar N., Mohanty, Shubhranshu S., Hadole, Bhushan S., Marathe, Nandan A., and Rai, Abhishek K.
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LONGITUDINAL ligaments ,CERVICAL vertebrae ,SPINAL cord diseases ,OSSIFICATION ,EXOSTOSIS ,CERVICAL spondylotic myelopathy ,HEMIPARESIS - Abstract
Background: Ossification of the posterior longitudinal ligament (OPLL) is a progressive disorder that mostly involves the cervical spine. It is more prevalent in East Asian countries. Patients typically present with the gradual onset of myelopathy, while about 5% show rapid progression. Case Description: A 51-year-old diabetic and hypertensive male presented with a left-sided hemiparesis following trivial trauma. The first diagnosis was a stroke, but the subsequent workup proved negative. Subsequently, the MRI and CT studies demonstrated significant cord compression due to OPLL extending from C2 to C7. There was also a heterogeneous hyperintense intramedullary cord signal indicative of edema/myelomalacia in the retroodontoid region. The CT also diagnosed C2-C7 diffuse idiopathic skeletal hyperostosis. Conclusion: Patients with cervical myelopathy due to OPLL rarely present about 5% of the time with the acute onset of neurological deficit following minor trauma. Certainly, one must consider high cervical OPLL as responsible for hemiparesis in a patient whose brain MR has ruled out a stroke. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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47. Inflammatory and Infectious Disorders of the Spine : Imaging Approach
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Wolf, Marcel, Weber, Marc-André, Muto, Mario, Section editor, Barkhof, Frederik, editor, Jäger, Hans Rolf, editor, Thurnher, Majda M., editor, and Rovira, Àlex, editor
- Published
- 2019
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48. Analyzing Control Parameters in DISH
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Viktorin, Adam, Senkerik, Roman, Pluhacek, Michal, Kadavy, Tomas, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Pandu Rangan, C., Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Rutkowski, Leszek, editor, Scherer, Rafał, editor, Korytkowski, Marcin, editor, Pedrycz, Witold, editor, Tadeusiewicz, Ryszard, editor, and Zurada, Jacek M., editor
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- 2019
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49. X-ray
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Pitzen, Joshua, Tariq, Umar, Weiss, Frederick, and Abd-Elsayed, Alaa, editor
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- 2019
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50. MID-Radio Telescope, Single Pixel Feed Packages for the Square Kilometer Array: An Overview
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Alice Pellegrini, Jonas Flygare, Isak P. Theron, Robert Lehmensiek, Adriaan Peens-Hough, Jamie Leech, Michael E. Jones, Angela C. Taylor, Robert E. J. Watkins, Lei Liu, Andre Hector, Biao Du, and Yang Wu
- Subjects
Dish ,MID-telescope ,radio astronomy ,radio telescope ,single pixel feed ,SKA ,Telecommunication ,TK5101-6720 ,Electric apparatus and materials. Electric circuits. Electric networks ,TK452-454.4 - Abstract
The Square Kilometre Array (SKA) project is an international effort to build the world's largest radio telescope, enabling science with unprecedented detail and survey speed.The project spans over a decade and is now at a mature stage, ready to enter the construction and integration phase. In the fully deployed state, the MID-Telescope consists of a 150-km diameter array of offset Gregorian antennas installed in the radio quiet zone of the Karoo desert (South Africa). Each antenna is equipped with three feed packages, that are precision positioned in the sub-reflector focus by a feed indexer platform. The total observational bandwidth (0.35-15.4GHz) is segmented into seven bands. Band 1 (0.35 - 1.05 GHz) and Band 2 (0.95 - 1.76 GHz) are implemented as individual feed packages. The remaining five bands (Bands 3, 4, 5a, 5b, and 6) are combined in a single feed package. Initially only Band 5a (4.6 - 8.5 GHz) and Band 5b (8.3 - 15.4 GHz) will be installed. This paper provides an overview of recent progress on design, test and integration of each feed package as well as project and science goals, timeline and path to construction.
- Published
- 2021
- Full Text
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