1. [Spinal granuloma in a patient receiving a spinal infusion of morphine and clonidine].
- Author
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Abejón D, del Saz JM, Ley L, Sánchez MR, and del Pozo C
- Subjects
- Analgesics, Opioid administration & dosage, Clonidine administration & dosage, Drug Therapy, Combination, Emergencies, Granuloma, Foreign-Body surgery, Hemangioma, Cavernous, Central Nervous System surgery, Humans, Infusions, Parenteral instrumentation, Laminectomy, Male, Middle Aged, Morphine administration & dosage, Muscle Relaxants, Central administration & dosage, Postoperative Complications drug therapy, Postoperative Complications surgery, Spinal Cord Compression surgery, Spinal Cord Diseases surgery, Analgesia, Epidural instrumentation, Analgesics, Opioid therapeutic use, Back Pain etiology, Catheterization adverse effects, Clonidine therapeutic use, Granuloma, Foreign-Body etiology, Infusion Pumps, Implantable adverse effects, Morphine therapeutic use, Muscle Relaxants, Central therapeutic use, Neuralgia etiology, Postoperative Complications etiology, Spinal Cord Compression etiology
- Abstract
Patients treated with long-term spinal infusion of high doses of morphine develop a granuloma at the location of the catheter tip. Diagnosis is based on a steady increase in intrathecal morphine dosage after a relatively prolonged period of stability, on the gradual development of neurologic signs and symptoms suggesting radicular or spinal cord compression, and on magnetic resonance images. We describe a man with central neuropathic pain after removal of a tumor. The presence of all 3 of the aforementioned diagnostic criteria led to suspicion of a spinal granuloma.
- Published
- 2009
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