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Regarding the Covid-19 pandemic, researchers continue to be concerned about topics that have not yet been elucidated, the complications of serious patients during and after COVID, as well as their relationship with vaccination, are interesting. Studies show good acceptance of the vaccine by the general population, however, 15-20% have doubts about its safety. The most frequent complications are pulmonary, extrapulmonary and neurological, the latter due to the property of respiratory viruses neurotropism, which causes neurovirulence damage. The body shows strong reaction against COVID-19. Nonetheless, it is stronger with the OxfordAstraZeneca Vaxzevria vaccine than with the Pfizer-BioNTech Comirnaty vaccine, which also results in serious neurological disorders. We searched PubMed for the last 3 years. The search engine returned 147 abstracts, they were evaluated for selection and inclusion. They were classified according to how they described vaccine and non-vaccine complications. Through the theoretical foundation of the research, the main complications recorded in the literature consulted were identified. The rates of vaccine complications are low in relation to the immunized population. Vaccines continue to be the main measure to strengthen immunity, which is reflected in fewer serious patients and hospitalizations. In many cases, similar vaccine and non-vaccine complications are observed, so the organism's response to the virus or to other components of the vaccine is involved in the pathogenesis. [ABSTRACT FROM AUTHOR]

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Copyright of Revista de Ciencias Médicas de Pinar del Río is the property of Editorial Ciencias Medicas and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)