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1. Challenges in the diagnosis of paediatric pneumonia in intervention field trials: recommendations from a pneumonia field trial working group

Author

Nambajimana, Abidan, Pillarisetti, Ajay, Verma, Amit, Lovvorn, Amy, Diaz, Anaité, Papageorghiou, Aris, Toenjes, Ashley, Quinn, Ashlinn, Nizam, Azhar, Ryan, Barry, Young, Bonnie, Barr, Dana, Goodman, Dina, Canuz, Eduardo, Puzzolo, Elisa, McCollum, Eric, Mollinedo, Erick, Majorin, Fiona, Ndagijimana, Florien, Rosa, Ghislaine, Thangavel, Gurusamy, Chang, Howard, Fuentes, Irma, Miranda, J Jaime, Ntivuguruzwa, JD, Uwizeyimana, Jean, Peel, Jennifer, Sarnat, Jeremy, Liao, Jiawen, McCracken, John, Rosenthal, Joshua, Espinoza, Juan, Campbell, JM, Balakrishnan, Kalpana, Williams, Kendra, Smith, Kirk, Mukhopadhyay, Krishnendu, Steenland, Kyle, Waller, Lance, Moulton, Lawrence, Jaacks, Lindsay, Underhill, Lindsay, de la Fuentes, Lisa, Elon, Lisa, Thompson, Lisa, Naeher, Luke, Clark, Maggie, Laws, Margaret, Chiang, Marilú, Howard, Marjorie, Crocker, Mary, Johnson, Michael, Kirby, Miles, Puttaswamy, Naveen, De Leon, Oscar, Herrera, Phabiola, Craik, Rachel, Merrick, Rachel, Piedrahita, Ricardo, Sambandam, Sankar, Garg, Sarada, Rajkumar, Sarah, Gupton, Savannah, Hossen, Shakir, Sinharoy, Sheela, Jabbarzadeh, Shirin, Hartinger, Stella, Harvey, Steven, Simkovich, Suzanne, Clasen, Thomas, Ramakrishnan, Usha, Burrowes, Vanessa, Davila-Roman, Victor, Aravindalochanan, Vigneswari, Checkley, William, Chen, Yunyun, Sakas, Zoe, Crocker, Mary E, Pervaiz, Farhan, McCollum, Eric D, Simkovich, Suzanne M, Miele, Catherine H, Hammitt, Laura L, Zar, Heather J, Campbell, Harry, Lanata, Claudio F, McCracken, John P, Thompson, Lisa M, Kirby, Miles A, Thanasekaraan, Vijayalakshmi, and King, Carina

Published
2019
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2. Compensating control participants when the intervention is of significant value: Experience in Guatemala, India, Peru and Rwanda

Author

Quinn, Ashlinn K, Williams, Kendra, Thompson, Lisa M, Rosa, Ghislaine, Diaz-Artiga, Anaite, Thangavel, Gurusamy, Balakrishnan, Kalpana, Miranda, J Jaime, Rosenthal, Joshua P, Clasen, Thomas F, Harvey, Steven A, Aravindalochanan, Vigneswari, Barr, Dana Boyd, Burrowes, Vanessa, Campbell, Devan, Campbell, Julia McPeek, Canuz, Eduardo, Castanaza, Adly, Chang, Howard, Checkley, William, Chen, Yunyun, Chiang, Marilu, Clark, Maggie L, Craik, Rachel, Crocker, Mary, Davila-Roman, Victor, de la Fuentes, Lisa, De Leon, Oscar, Dusabimana, Ephrem, Elon, Lisa, Gabriel Espinoza, Juan, Pineda Fuentes, Irma Sayury, Garg, Sarada, Goodman, Dina, Gupton, Savannah, Hardison, Megan, Hartinger, Stella, Herrera, Phabiola, Hossen, Shakir, Jaacks, Lindsay, Jabbarzadeh, Shirin, Johnson, Michael A, Jones, Abigail, Kearns, Katherine, Kirby, Miles, Kremer, Jacob, Laws, Margaret, Liao, Jiawen, Lovvorn, Amy, Majorin, Fiona, McCollum, Eric, McCracken, John, Meyers, Rachel, Mollinedo, Erick, Moulton, Lawrence, Mukhopadhyay, Krishnendu, Naeher, Luke, Nambajimana, Abidan, Ndagijimana, Florien, Nizam, Azhar, Ntivuguruzwa, Jean de Dieu, Papageorghiou, Aris, Peel, Jennifer, Piedrahita, Ricardo, Pillarisetti, Ajay, Puttaswamy, Naveen, Puzzolo, Elisa, Rajkumar, Sarah, Ramakrishnan, Usha, Reardon, David, Ryan, P Barry, Sakas, Zoe, Sambandam, Sankar, Sarnat, Jeremy, Simkovich, Suzanne, Sinharoy, Sheela, Smith, Kirk R, Steenland, Kyle, Swearing, Damien, Toenjes, Ashley, Underhill, Lindsay, Uwizeyimana, Jean Damascene, Valdes, Viviane, Verma, Amit, Waller, Lance, Warnock, Megan, Young, Bonnie, Investigators, HAPIN, Investigators, HAPIN, and Papageorghiou, A

Subjects
purl.org/pe-repo/ocde/ford#3.03.05 [https], Cash and cash equivalents, Control (management), 010501 environmental sciences, 01 natural sciences, Liquefied petroleum gas, Household economics, law.invention, compensation, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, purl.org/pe-repo/ocde/ford#3.03.02 [https], law, 030212 general & internal medicine, Socioeconomics, 0105 earth and related environmental sciences, 2. Zero hunger, Practice, Health Policy, Public Health, Environmental and Occupational Health, multi-country trial, ethics, Local community, Intervention (law), Stove, Business, randomised controlled trial
Abstract

The Household Air Pollution Intervention Network (HAPIN) trial is a randomised controlled trial in Guatemala, India, Peru and Rwanda to assess the health impact of a clean cooking intervention in households using solid biomass for cooking. The HAPIN intervention—a liquefied petroleum gas (LPG) stove and 18-month supply of LPG—has significant value in these communities, irrespective of potential health benefits. For control households, it was necessary to develop a compensation strategy that would be comparable across four settings and would address concerns about differential loss to follow-up, fairness and potential effects on household economics. Each site developed slightly different, contextually appropriate compensation packages by combining a set of uniform principles with local community input. In Guatemala, control compensation consists of coupons equivalent to the LPG stove’s value that can be redeemed for the participant’s choice of household items, which could include an LPG stove. In Peru, control households receive several small items during the trial, plus the intervention stove and 1 month of fuel at the trial’s conclusion. Rwandan participants are given small items during the trial and a choice of a solar kit, LPG stove and four fuel refills, or cash equivalent at the end. India is the only setting in which control participants receive the intervention (LPG stove and 18 months of fuel) at the trial’s end while also being compensated for their time during the trial, in accordance with local ethics committee requirements. The approaches presented here could inform compensation strategy development in future multi-country trials.

Published
2020

3. Comparison of next-generation portable pollution monitors to measure exposure to PM(2.5) from household air pollution in Puno, Peru

Author

Burrowes, Vanessa J., Piedrahita, Ricardo, Pillarisetti, Ajay, Underhill, Lindsay J., Fandino-Del-Rio, Magdalena, Johnson, Michael, Kephart, Josiah L., Hartinger Peña, Stella Maria, Steenland, Kyle, Naeher, Luke, Kearns, Katie, Peel, Jennifer L., Clark, Maggie L., Checkley, William, Balakrishnan, Kalpana, Clasen, Thomas, McCracken, John, Peel, Jennifer, Rosa, Ghislaine, Rosenthal, Joshua, Thompson, Lisa, Aravindalochanan, Vigneswari, Garg, Sarada, Thangavel, Gurusamy, Mukhopadhyay, Krishnendu, Puttaswamy, Naveen, Sambandam, Sankar, De Leon, Oscar, Mollinedo, Erick, Diaz, Anaite, Pineda Fuentes, Irma Sayury, Burrowes, Vanessa, Canuz, Eduardo, Chiang, Marilu, Herrera, Phabiola, Laws, Margaret, Moulton, Lawrence, Simkovich, Suzanne, Underhill, Lindsay, Williams, Kendra, Ntivuguruzwa, Jean de Dieu, Kirby, Miles, Majorin, Fiona, Nambajimana, Abidan, Ndagijimana, Florien, Uwizeyimana, Jean, Harvey, Steven, Howard, Marjorie, Miranda, J. Jaime, Puzzolo, Elisa, Quinn, Ashlinn, Sakas, Zoe, Barr, Dana, Campbell, Julia McPeek, Clark, Maggie, Gupton, Savannah, Rajkumar, Sarah, Ryan, Barry, Young, Bonnie, Chang, Howard, Chen, Yunyun, Elon, Lisa, Jaacks, Lindsay, Jabbarzadeh, Shirin, Lovvorn, Amy, Nizam, Azhar, Verma, Amit, Waller, Lance, Craik, Rachel, Merrick, Rachel, Davila-Roman, Victor, de la Fuentes, Lisa, Papageorghiou, Aris, Toenjes, Ashley, Liao, Jiawen, Sarnat, Jeremy, Smith, Kirk, Ramakrishnan, Usha, Sinharoy, Sheela, Crocker, Mary, Goodman, Dina, Hossen, Shakir, McCollum, Eric, and Gabriel Espinoza, Juan

Subjects
Pollution, particulate matter, Environmental Engineering, 010504 meteorology & atmospheric sciences, purl.org/pe-repo/ocde/ford#3.03.05 [https], media_common.quotation_subject, Public Health, Environmental and Occupational Health, Air pollution, household air pollution, purl.org/pe-repo/ocde/ford#2.01.03 [https], Air sampler, Building and Construction, 010501 environmental sciences, medicine.disease_cause, Atmospheric sciences, 01 natural sciences, Mean difference, medicine, Environmental science, Exposure measurement, lower- and middle-income countries, 0105 earth and related environmental sciences, media_common, Exposure assessment
Abstract

Assessment of personal exposure to PM2.5 is critical for understanding intervention effectiveness and exposure-response relationships in household air pollution studies. In this pilot study, we compared PM2.5 concentrations obtained from two next-generation personal exposure monitors (the Enhanced Children MicroPEM or ECM; and the Ultrasonic Personal Air Sampler or UPAS) to those obtained with a traditional Triplex Cyclone and SKC Air Pump (a gravimetric cyclone/pump sampler). We co-located cyclone/pumps with an ECM and UPAS to obtain 24-hour kitchen concentrations and personal exposure measurements. We measured Spearmen correlations and evaluated agreement using the Bland-Altman method. We obtained 215 filters from 72 ECM and 71 UPAS co-locations. Overall, the ECM and the UPAS had similar correlation (ECM ρ = 0.91 vs UPAS ρ = 0.88) and agreement (ECM mean difference of 121.7 µg/m3 vs UPAS mean difference of 93.9 µg/m3 ) with overlapping confidence intervals when compared against the cyclone/pump. When adjusted for the limit of detection, agreement between the devices and the cyclone/pump was also similar for all samples (ECM mean difference of 68.8 µg/m3 vs UPAS mean difference of 65.4 µg/m3 ) and personal exposure samples (ECM mean difference of -3.8 µg/m3 vs UPAS mean difference of -12.9 µg/m3 ). Both the ECM and UPAS produced comparable measurements when compared against a cyclone/pump setup.

Published
2020

4. Challenges in the diagnosis of paediatric pneumonia in intervention field trials: recommendations from a pneumonia field trial working group

Author

Goodman, Dina, primary, Crocker, Mary E, additional, Pervaiz, Farhan, additional, McCollum, Eric D, additional, Steenland, Kyle, additional, Simkovich, Suzanne M, additional, Miele, Catherine H, additional, Hammitt, Laura L, additional, Herrera, Phabiola, additional, Zar, Heather J, additional, Campbell, Harry, additional, Lanata, Claudio F, additional, McCracken, John P, additional, Thompson, Lisa M, additional, Rosa, Ghislaine, additional, Kirby, Miles A, additional, Garg, Sarada, additional, Thangavel, Gurusamy, additional, Thanasekaraan, Vijayalakshmi, additional, Balakrishnan, Kalpana, additional, King, Carina, additional, Clasen, Thomas, additional, Checkley, William, additional, Nambajimana, Abidan, additional, Pillarisetti, Ajay, additional, Verma, Amit, additional, Lovvorn, Amy, additional, Diaz, Anaité, additional, Papageorghiou, Aris, additional, Toenjes, Ashley, additional, Quinn, Ashlinn, additional, Nizam, Azhar, additional, Ryan, Barry, additional, Young, Bonnie, additional, Barr, Dana, additional, Goodman, Dina, additional, Canuz, Eduardo, additional, Puzzolo, Elisa, additional, McCollum, Eric, additional, Mollinedo, Erick, additional, Majorin, Fiona, additional, Ndagijimana, Florien, additional, Chang, Howard, additional, Fuentes, Irma, additional, Miranda, J Jaime, additional, Ntivuguruzwa, JD, additional, Uwizeyimana, Jean, additional, Peel, Jennifer, additional, Sarnat, Jeremy, additional, Liao, Jiawen, additional, McCracken, John, additional, Rosenthal, Joshua, additional, Espinoza, Juan, additional, Campbell, JM, additional, Williams, Kendra, additional, Smith, Kirk, additional, Mukhopadhyay, Krishnendu, additional, Waller, Lance, additional, Moulton, Lawrence, additional, Jaacks, Lindsay, additional, Underhill, Lindsay, additional, de la Fuentes, Lisa, additional, Elon, Lisa, additional, Thompson, Lisa, additional, Naeher, Luke, additional, Clark, Maggie, additional, Laws, Margaret, additional, Chiang, Marilú, additional, Howard, Marjorie, additional, Crocker, Mary, additional, Johnson, Michael, additional, Kirby, Miles, additional, Puttaswamy, Naveen, additional, De Leon, Oscar, additional, Craik, Rachel, additional, Merrick, Rachel, additional, Piedrahita, Ricardo, additional, Sambandam, Sankar, additional, Rajkumar, Sarah, additional, Gupton, Savannah, additional, Hossen, Shakir, additional, Sinharoy, Sheela, additional, Jabbarzadeh, Shirin, additional, Hartinger, Stella, additional, Harvey, Steven, additional, Simkovich, Suzanne, additional, Ramakrishnan, Usha, additional, Burrowes, Vanessa, additional, Davila-Roman, Victor, additional, Aravindalochanan, Vigneswari, additional, Chen, Yunyun, additional, and Sakas, Zoe, additional

Published
2019
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