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Copyright of Brazilian Journal of Surgery & Clinical Research is the property of Master Editora and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

El dolor ciático es una patología inhabilitante que puede tener diversas etiologías, pero rara vez se describe como causada por un lipoma glúteo intermuscular. Los autores describen a un paciente con un dolor ciática derecha que empeora progresivamente durante 6 meses y con dificultad para caminar durante 3 meses. La resonancia magnética (RM) mostró un proceso expansivo compatible con lipoma entre el gluteo máximo, y el glúteo medio. El lipoma fue retirado por completo y sin lesión del nervio ciático. Después de la cirugía, el paciente está asintomático. Este es un caso inusual y representa un importante diagnóstico diferencial que debe ser considerado en los pacientes con ciática. Palabras clave: Ciática, Lipoma, Hernia Discal Lumbar. Sciatic pain is a disabling pathology that can have various etiologies, but is rarely described as caused by an intermuscular gluteal lipoma. The authors describe a patient with a progressively worsening right sciatic pain for 6 months and with walking difficulty for 3 months. Magnetic resonance imaging (MRI) showed an expansive process compatible with lipoma between the gluteus maximus and medius, which was completely removed without sciatic nerve injury. After surgery, the patient is asymptomatic. This is an unusual case and represents an important differential diagnosis that should be considered in sciatic pain patients. Key words: Sciatica, Lipoma, Lumbar Disc Herniation., Introduction Lipoma is the most common benign tumor of soft tissues. It consists mainly of fatty tissue, usually subcutaneous, but when occurring in deeper tissues it may compress adjacent structures [...]

Copyright of Universidade Estadual Paulista. Revista de Odontologia is the property of Universidade Estadual Paulista. Revista de Odontologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives: Keratocystic odontogenic tumors (KOTs), also known as odontogenic keratocysts, were recently classified as a benign neoplasia due to the aggressive clinical behavior. Although several studies have shown the high proliferative activity of the epithelial lining, few studies have evaluated apoptosis in KOTs. Therefore, the aim of this study is to evaluate and compare the proliferation index (PI) and the apoptotic index (AI) of the epithelial lining in sporadic KOTs, KOTs associated with the Nevoid Basal Cell Carcinoma Syndrome (NBCCS KOTs), and dentigerous cysts., Material and Methods: A total of 11 sporadic KOTs, 15 NBCCS KOTs, and 11 dentigerous cysts were evaluated. The PI was assessed by immunohistochemical detection of the cell proliferation marker Ki-67. The AI was assessed by morphological evaluation of sections stained by methyl green-pyronin. The TUNEL assay was used to confirm the occurrence of apoptosis. Differences in the PI and the AI between sporadic KOTs, NBCCS KOTs, and dentigerous cysts were analyzed using the Kruskal-Wallis test. Differences in the PI and the AI between the epithelial layers of each lesion were analyzed using the Wilcoxon test., Results: The PI and AI were higher in sporadic and NBCCS KOTs than in dentigerous cysts. No difference in these indexes was observed between sporadic and NBCCS KOTs. In dentigerous cysts, the PI was higher in the basal layer. In sporadic and NBCCS KOTs, the PI was higher in suprabasal layer. No difference in the AI was observed between the basal layer and the suprabasal layer in the three lesions. The AI was higher in the superficial layer of sporadic and NBCCS KOTs., Conclusions: The present study demonstrates that the epithelial lining of KOTs shows a distinct pattern of cell proliferation and apoptosis, reflecting its high cell turnover and reinforcing its classification as an odontogenic tumor.