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1. Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor

Author

Turpin, Anthony, Delliaux, Carine, Parent, Pauline, Chevalier, Hortense, Escudero-Iriarte, Carmen, Bonardi, Franck, Vanpouille, Nathalie, Flourens, Anne, Querol, Jessica, Carnot, Aurélien, Leroy, Xavier, Herranz, Nicolás, Lanel, Tristan, Villers, Arnauld, Olivier, Jonathan, Touzet, Hélène, de Launoit, Yvan, Tian, Tian V., and Duterque-Coquillaud, Martine

Published
2023
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2. Aberrant up-regulation of iNOS/NO system is correlated with an increased abundance of Foxp3+ cells and reduced effector/memory cell markers expression during colorectal cancer: immunomodulatory effects of cetuximab combined with chemotherapy

Author

Benkhelifa, Sarra, Rafa, Hayet, Belhadef, Said, Ait-kaci, Hayat, Medjeber, Oussama, Belkhelfa, Mourad, Hetit, Sabah, Ait-Younes, Sonia, De launoit, Yvan, Moralès, Olivier, Mahfouf, Hassen, Delhem, Nadira, and Touil-Boukoffa, Chafia

Published
2019
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4. Supplementary Figure S6 from Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer

Author

Duplaquet, Leslie, primary, Figeac, Martin, primary, Leprêtre, Frédéric, primary, Frandemiche, Charline, primary, Villenet, Céline, primary, Sebda, Shéhérazade, primary, Sarafan-Vasseur, Nasrin, primary, Bénozène, Mélanie, primary, Vinchent, Audrey, primary, Goormachtigh, Gautier, primary, Wicquart, Laurence, primary, Rousseau, Nathalie, primary, Beaussire, Ludivine, primary, Truant, Stéphanie, primary, Michel, Pierre, primary, Sabourin, Jean-Christophe, primary, Galateau-Sallé, Françoise, primary, Copin, Marie-Christine, primary, Zalcman, Gérard, primary, De Launoit, Yvan, primary, Fafeur, Véronique, primary, and Tulasne, David, primary

Published
2023
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7. Data from Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer

Author

Duplaquet, Leslie, primary, Figeac, Martin, primary, Leprêtre, Frédéric, primary, Frandemiche, Charline, primary, Villenet, Céline, primary, Sebda, Shéhérazade, primary, Sarafan-Vasseur, Nasrin, primary, Bénozène, Mélanie, primary, Vinchent, Audrey, primary, Goormachtigh, Gautier, primary, Wicquart, Laurence, primary, Rousseau, Nathalie, primary, Beaussire, Ludivine, primary, Truant, Stéphanie, primary, Michel, Pierre, primary, Sabourin, Jean-Christophe, primary, Galateau-Sallé, Françoise, primary, Copin, Marie-Christine, primary, Zalcman, Gérard, primary, De Launoit, Yvan, primary, Fafeur, Véronique, primary, and Tulasne, David, primary

Published
2023
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8. Supplementary Table S1 from Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer

Author

Duplaquet, Leslie, primary, Figeac, Martin, primary, Leprêtre, Frédéric, primary, Frandemiche, Charline, primary, Villenet, Céline, primary, Sebda, Shéhérazade, primary, Sarafan-Vasseur, Nasrin, primary, Bénozène, Mélanie, primary, Vinchent, Audrey, primary, Goormachtigh, Gautier, primary, Wicquart, Laurence, primary, Rousseau, Nathalie, primary, Beaussire, Ludivine, primary, Truant, Stéphanie, primary, Michel, Pierre, primary, Sabourin, Jean-Christophe, primary, Galateau-Sallé, Françoise, primary, Copin, Marie-Christine, primary, Zalcman, Gérard, primary, De Launoit, Yvan, primary, Fafeur, Véronique, primary, and Tulasne, David, primary

Published
2023
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16. Supplementary Table 2 from Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells

Author

Dessein, Anne-Frédérique, primary, Stechly, Laurence, primary, Jonckheere, Nicolas, primary, Dumont, Patrick, primary, Monté, Didier, primary, Leteurtre, Emmanuelle, primary, Truant, Stéphanie, primary, Pruvot, François-René, primary, Figeac, Martin, primary, Hebbar, Mohamed, primary, Lecellier, Charles-Henri, primary, Lesuffleur, Thécla, primary, Dessein, Rodrigue, primary, Grard, Georges, primary, Dejonghe, Marie-José, primary, de Launoit, Yvan, primary, Furuichi, Yasuhiro, primary, Prévost, Grégoire, primary, Porchet, Nicole, primary, Gespach, Christian, primary, and Huet, Guillemette, primary

Published
2023
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17. Supplementary Video 1 from Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Author

Gosselin, Karo, primary, Martien, Sébastien, primary, Pourtier, Albin, primary, Vercamer, Chantal, primary, Ostoich, Peter, primary, Morat, Luc, primary, Sabatier, Laure, primary, Duprez, Laurence, primary, T'Kint de Roodenbeke, Claire, primary, Gilson, Eric, primary, Malaquin, Nicolas, primary, Wernert, Nicolas, primary, Slijepcevic, Predrag, primary, Ashtari, Marjan, primary, Chelli, Fazia, primary, Deruy, Emeric, primary, Vandenbunder, Bernard, primary, De Launoit, Yvan, primary, and Abbadie, Corinne, primary

Published
2023
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18. Supplementary Methods from Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Author

Gosselin, Karo, primary, Martien, Sébastien, primary, Pourtier, Albin, primary, Vercamer, Chantal, primary, Ostoich, Peter, primary, Morat, Luc, primary, Sabatier, Laure, primary, Duprez, Laurence, primary, T'Kint de Roodenbeke, Claire, primary, Gilson, Eric, primary, Malaquin, Nicolas, primary, Wernert, Nicolas, primary, Slijepcevic, Predrag, primary, Ashtari, Marjan, primary, Chelli, Fazia, primary, Deruy, Emeric, primary, Vandenbunder, Bernard, primary, De Launoit, Yvan, primary, and Abbadie, Corinne, primary

Published
2023
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19. Supplementary Table 1 from Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells

Author

Dessein, Anne-Frédérique, primary, Stechly, Laurence, primary, Jonckheere, Nicolas, primary, Dumont, Patrick, primary, Monté, Didier, primary, Leteurtre, Emmanuelle, primary, Truant, Stéphanie, primary, Pruvot, François-René, primary, Figeac, Martin, primary, Hebbar, Mohamed, primary, Lecellier, Charles-Henri, primary, Lesuffleur, Thécla, primary, Dessein, Rodrigue, primary, Grard, Georges, primary, Dejonghe, Marie-José, primary, de Launoit, Yvan, primary, Furuichi, Yasuhiro, primary, Prévost, Grégoire, primary, Porchet, Nicole, primary, Gespach, Christian, primary, and Huet, Guillemette, primary

Published
2023
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21. Supplementary Figure 1 from Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells

Author

Dessein, Anne-Frédérique, primary, Stechly, Laurence, primary, Jonckheere, Nicolas, primary, Dumont, Patrick, primary, Monté, Didier, primary, Leteurtre, Emmanuelle, primary, Truant, Stéphanie, primary, Pruvot, François-René, primary, Figeac, Martin, primary, Hebbar, Mohamed, primary, Lecellier, Charles-Henri, primary, Lesuffleur, Thécla, primary, Dessein, Rodrigue, primary, Grard, Georges, primary, Dejonghe, Marie-José, primary, de Launoit, Yvan, primary, Furuichi, Yasuhiro, primary, Prévost, Grégoire, primary, Porchet, Nicole, primary, Gespach, Christian, primary, and Huet, Guillemette, primary

Published
2023
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22. Supplementary Figures 1-8 from Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Author

Gosselin, Karo, primary, Martien, Sébastien, primary, Pourtier, Albin, primary, Vercamer, Chantal, primary, Ostoich, Peter, primary, Morat, Luc, primary, Sabatier, Laure, primary, Duprez, Laurence, primary, T'Kint de Roodenbeke, Claire, primary, Gilson, Eric, primary, Malaquin, Nicolas, primary, Wernert, Nicolas, primary, Slijepcevic, Predrag, primary, Ashtari, Marjan, primary, Chelli, Fazia, primary, Deruy, Emeric, primary, Vandenbunder, Bernard, primary, De Launoit, Yvan, primary, and Abbadie, Corinne, primary

Published
2023
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23. Data from Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells

Author

Dessein, Anne-Frédérique, primary, Stechly, Laurence, primary, Jonckheere, Nicolas, primary, Dumont, Patrick, primary, Monté, Didier, primary, Leteurtre, Emmanuelle, primary, Truant, Stéphanie, primary, Pruvot, François-René, primary, Figeac, Martin, primary, Hebbar, Mohamed, primary, Lecellier, Charles-Henri, primary, Lesuffleur, Thécla, primary, Dessein, Rodrigue, primary, Grard, Georges, primary, Dejonghe, Marie-José, primary, de Launoit, Yvan, primary, Furuichi, Yasuhiro, primary, Prévost, Grégoire, primary, Porchet, Nicole, primary, Gespach, Christian, primary, and Huet, Guillemette, primary

Published
2023
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24. Data from PLA2R1 Mediates Tumor Suppression by Activating JAK2

Author

Vindrieux, David, primary, Augert, Arnaud, primary, Girard, Christophe A., primary, Gitenay, Delphine, primary, Lallet-Daher, Helene, primary, Wiel, Clotilde, primary, Le Calvé, Benjamin, primary, Gras, Baptiste, primary, Ferrand, Mylène, primary, Verbeke, Stéphanie, primary, de Launoit, Yvan, primary, Leroy, Xavier, primary, Puisieux, Alain, primary, Aubert, Sébastien, primary, Perrais, Michael, primary, Gelb, Michael, primary, Simonnet, Hélène, primary, Lambeau, Gérard, primary, and Bernard, David, primary

Published
2023
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25. Supplementary Methods, Figure Legends 1 from Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells

Author

Dessein, Anne-Frédérique, primary, Stechly, Laurence, primary, Jonckheere, Nicolas, primary, Dumont, Patrick, primary, Monté, Didier, primary, Leteurtre, Emmanuelle, primary, Truant, Stéphanie, primary, Pruvot, François-René, primary, Figeac, Martin, primary, Hebbar, Mohamed, primary, Lecellier, Charles-Henri, primary, Lesuffleur, Thécla, primary, Dessein, Rodrigue, primary, Grard, Georges, primary, Dejonghe, Marie-José, primary, de Launoit, Yvan, primary, Furuichi, Yasuhiro, primary, Prévost, Grégoire, primary, Porchet, Nicole, primary, Gespach, Christian, primary, and Huet, Guillemette, primary

Published
2023
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26. Supplementary Table 1 from Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Author

Gosselin, Karo, primary, Martien, Sébastien, primary, Pourtier, Albin, primary, Vercamer, Chantal, primary, Ostoich, Peter, primary, Morat, Luc, primary, Sabatier, Laure, primary, Duprez, Laurence, primary, T'Kint de Roodenbeke, Claire, primary, Gilson, Eric, primary, Malaquin, Nicolas, primary, Wernert, Nicolas, primary, Slijepcevic, Predrag, primary, Ashtari, Marjan, primary, Chelli, Fazia, primary, Deruy, Emeric, primary, Vandenbunder, Bernard, primary, De Launoit, Yvan, primary, and Abbadie, Corinne, primary

Published
2023
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27. Supplementary Table 2 from Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Author

Gosselin, Karo, primary, Martien, Sébastien, primary, Pourtier, Albin, primary, Vercamer, Chantal, primary, Ostoich, Peter, primary, Morat, Luc, primary, Sabatier, Laure, primary, Duprez, Laurence, primary, T'Kint de Roodenbeke, Claire, primary, Gilson, Eric, primary, Malaquin, Nicolas, primary, Wernert, Nicolas, primary, Slijepcevic, Predrag, primary, Ashtari, Marjan, primary, Chelli, Fazia, primary, Deruy, Emeric, primary, Vandenbunder, Bernard, primary, De Launoit, Yvan, primary, and Abbadie, Corinne, primary

Published
2023
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28. Data from Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Author

Gosselin, Karo, primary, Martien, Sébastien, primary, Pourtier, Albin, primary, Vercamer, Chantal, primary, Ostoich, Peter, primary, Morat, Luc, primary, Sabatier, Laure, primary, Duprez, Laurence, primary, T'Kint de Roodenbeke, Claire, primary, Gilson, Eric, primary, Malaquin, Nicolas, primary, Wernert, Nicolas, primary, Slijepcevic, Predrag, primary, Ashtari, Marjan, primary, Chelli, Fazia, primary, Deruy, Emeric, primary, Vandenbunder, Bernard, primary, De Launoit, Yvan, primary, and Abbadie, Corinne, primary

Published
2023
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29. Supplementary Table 1, Figures 1 - 8 from PLA2R1 Mediates Tumor Suppression by Activating JAK2

Author

Vindrieux, David, primary, Augert, Arnaud, primary, Girard, Christophe A., primary, Gitenay, Delphine, primary, Lallet-Daher, Helene, primary, Wiel, Clotilde, primary, Le Calvé, Benjamin, primary, Gras, Baptiste, primary, Ferrand, Mylène, primary, Verbeke, Stéphanie, primary, de Launoit, Yvan, primary, Leroy, Xavier, primary, Puisieux, Alain, primary, Aubert, Sébastien, primary, Perrais, Michael, primary, Gelb, Michael, primary, Simonnet, Hélène, primary, Lambeau, Gérard, primary, and Bernard, David, primary

Published
2023
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30. Flow Cytometry-based Method for Efficient Sorting of Senescent Cells

Author

Goy, Erwan, primary, Martin, Nathalie, additional, Drullion, Claire, additional, Saas, Laure, additional, Molendi-Coste, Olivier, additional, Pineau, Laurent, additional, Dombrowicz, David, additional, Deruy, Emeric, additional, Bauderlique-Leroy, Hélène, additional, Samyn, Olivier, additional, Nassour, Joe, additional, de Launoit, Yvan, additional, and Abbadie, Corinne, additional

Published
2023
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33. Effects of competitive research training funding on the careers of medical doctors

Author

Castagner, François, Chollet, Emmanuelle, Chomienne, Christine, de Launoit, Yvan, Eychène, Alain, and Altabef, Muriel

Abstract

Only few laureates of a M2 degree were continuing with research activities. Although several factors are influencing the decision to engage significantly in research, as analysed by Amgad and colleagues (2015), some laureates might have done a M2 degree in research to fulfil the requirements of such a degree to pretend to senior tenure positions in a hospital department in France. A return to clinical activities between a Master 2 degree and a PhD in research was often observed, deemed by former laureates as important for clinical expertise and insured senior tenure positions. Even if the hindsight did not allow us to have the complete career paths, we observed a clear tendency for doctorate laureates to engage more in career paths involving research. The career wishes as expressed by laureates were also presenting a clear shift after a PhD with more laureates reporting wishes to have research activities, albeit mostly together with clinical work. Interestingly, the fulfilment of those wishes was also increasing with the doctorate laureates having a career mostly in accordance to the expressed wishes. The medical students of the contrafactual group were less likely to be involved in research later in their careers even though all of them did a PhD thesis funded by other means. This could be explained either by an attractiveness of the programme that successfully recruited or selected medical students interested in research or by features of the programme that allowed the laureates to perform well in research. This study on medical students laureates of research trainings therefore indicates that engaging in a PhD thesis in research is more indicative of future research activities than a Master 2 degree. The scope of the programme has been reassessed upon this analysis to focus on PhD thesis grants.

Published
2022
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45. PEA3 transcription factors are expressed in tissues undergoing branching morphogenesis and promote formation of duct-like structures by mammary epithelial cells in vitro

Author

Chotteau-Lelievre, Anne, Montesano, Roberto, Soriano, Jesus, Soulie, Priscilla, Desbiens, Xavier, and de Launoit, Yvan

Subjects
Genetic transcription -- Research, Mammary glands -- Research, Morphogenesis -- Research, Biological sciences
Abstract

The genetic program that controls reciprocal tissue interactions during epithelial organogenesis is still poorly understood. Erm, Er81 and Pea3 are three highly related transcription factors belonging to the Ets family, within which they form the PEA3 group. Little information is yet available regarding the function of these transcription factors. We have previously used in situ hybridization to compare their expression pattern during critical stages of murine embryogenesis [Oncogene 15 (1997), 937; Mech. Dev. 108 (2001), 191]. In this study, we have examined the expression of PEA3 group members during organogenesis of the lung, salivary gland, kidney, and mammary gland. In all of these developmental settings, we observed a tight correlation between branching morphogenesis and the expression of specific members of the PEA3 group. To assess the functional relevance of these findings, Erm and Pea3 were overexpressed in the TAC-2.1 mammary epithelial cell line, which has the ability to form branching duct-like structures when grown in collagen gels. We found that overexpression of Erm and Pea3 markedly enhances branching tubulogenesis of TAC-2.1 cells and also promotes their invasion into a collagen matrix. Collectively, these findings suggest that the differential expression of PEA3 group transcription factors has an important role in the regulation of branching morphogenesis and raise the question of their implication in branching signaling. Keywords: PEA3; Transcription factors; Branching morphogenesis; Mammary development; Mammary cells; Expression analysis; Mouse

Published
2003

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