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3. Clinicopathological Factors as Predictors for Establishment of Patient Derived Head and Neck Squamous Cell Carcinoma Organoids

Author

MS Mondziekten/Kaakchirurgie, Pathologie Moleculair, MS Medische Oncologie, Cancer, MS Hoofd-Hals Chirurgische Oncologie, Pathologie Pathologen staf, de Kort, W W B, Millen, R, Driehuis, E, Devriese, L A, van Es, R J J, Willems, S M, MS Mondziekten/Kaakchirurgie, Pathologie Moleculair, MS Medische Oncologie, Cancer, MS Hoofd-Hals Chirurgische Oncologie, Pathologie Pathologen staf, de Kort, W W B, Millen, R, Driehuis, E, Devriese, L A, van Es, R J J, and Willems, S M

Published
2024

5. p-mTOR, p-ERK and PTEN Expression in Tumor Biopsies and Organoids as Predictive Biomarkers for Patients with HPV Negative Head and Neck Cancer

Author

Pathologie Research, MKA/BT Onderzoek, Pathologie Opleiding, Cancer, Onderzoek Beeld, Pathologie Moleculair, MS Medische Oncologie, MS Bijzondere Tandheelkunde, MS Hoofd-Hals Chirurgische Oncologie, Pathologie Pathologen staf, de Kort, W. W.B., de Ruiter, E. J., Haakma, W. E., Driehuis, E., Devriese, L. A., van Es, R. J.J., Willems, S. M., Pathologie Research, MKA/BT Onderzoek, Pathologie Opleiding, Cancer, Onderzoek Beeld, Pathologie Moleculair, MS Medische Oncologie, MS Bijzondere Tandheelkunde, MS Hoofd-Hals Chirurgische Oncologie, Pathologie Pathologen staf, de Kort, W. W.B., de Ruiter, E. J., Haakma, W. E., Driehuis, E., Devriese, L. A., van Es, R. J.J., and Willems, S. M.

Published
2023

6. A Novel Method for Quantitative Three-Dimensional Analysis of Zygomatico-Maxillary Complex Symmetry

Author

MKA/BT Onderzoek, Cancer, MS Hoofd-Hals Chirurgische Oncologie, Zorgeenheid MKA/BT Medisch, Other research (not in main researchprogram), de Kort, W W B, van Hout, W M M T, Ten Harkel, T C, van Cann, E M, Rosenberg, A J W P, MKA/BT Onderzoek, Cancer, MS Hoofd-Hals Chirurgische Oncologie, Zorgeenheid MKA/BT Medisch, Other research (not in main researchprogram), de Kort, W W B, van Hout, W M M T, Ten Harkel, T C, van Cann, E M, and Rosenberg, A J W P

Published
2022

7. Zygomaticomaxillary complex fracture repair with intraoperative CBCT imaging. A prospective cohort study

Author

MKA/BT Onderzoek, Cancer, Pathologie Groep Moelans, DHS 3D Lab, MS Hoofd-Hals Chirurgische Oncologie, Zorgeenheid MKA/BT Medisch, Other research (not in main researchprogram), van Hout, W. M.M.T., de Kort, W. W.B., ten Harkel, T. C., Van Cann, E. M., Rosenberg, A. J.W.P., MKA/BT Onderzoek, Cancer, Pathologie Groep Moelans, DHS 3D Lab, MS Hoofd-Hals Chirurgische Oncologie, Zorgeenheid MKA/BT Medisch, Other research (not in main researchprogram), van Hout, W. M.M.T., de Kort, W. W.B., ten Harkel, T. C., Van Cann, E. M., and Rosenberg, A. J.W.P.

Published
2022

17. Predictive Value of EGFR-PI3K-AKT-mTOR-Pathway Inhibitor Biomarkers for Head and Neck Squamous Cell Carcinoma: A Systematic Review

Author

Pathologie Groep Moelans, Pathologie Algemene Pat.zorg, Longziekten onderzoek 2, MS Medische Oncologie, Cancer, MKA/BT Onderzoek, MS Hoofd-Hals Chirurgische Oncologie, Pathologie Pathologen staf, de Kort, W. W.B., Spelier, S., Devriese, L. A., van Es, R. J.J., Willems, S. M., Pathologie Groep Moelans, Pathologie Algemene Pat.zorg, Longziekten onderzoek 2, MS Medische Oncologie, Cancer, MKA/BT Onderzoek, MS Hoofd-Hals Chirurgische Oncologie, Pathologie Pathologen staf, de Kort, W. W.B., Spelier, S., Devriese, L. A., van Es, R. J.J., and Willems, S. M.

Published
2021

19. Samen beslissen: De stand van zaken in de dermatologie en ontwikkeling van een keuzehulp psoriasis

Author

van der Kraaij, G. E., Baerveldt, E. M., Boshuizen, M., Determann, D., van Ee, I., Hageman, M., van Huizen, A. M., de Kort, W. J. A., Tafuni, G., Smeets, P. M. G., Smets, E. M. A., Vermeulen, F. M., Spuls, Ph. I., Dermatology, Graduate School, AII - Inflammatory diseases, APH - Methodology, APH - Quality of Care, Medical Psychology, and APH - Personalized Medicine

Published
2020

43. Prevalence of alexithymia in patients with psoriasis and its association with disease burden: a multicentre observational study

Author

Sampogna, F., Puig, L., Spuls, P., Girolomoni, G., Radtke, M. A., Kirby, B., Brunori, M., Bergmans, P., Smirnov, P., Rundle, J., Lavie, F., Paul, C., Affleck, A., Antoniou, C., Ayala, F., Bakulev, A., Bam, E., Belinchon, I., Bewley, A., Botella, R., Chasapi, V., Chimenti, S., Cianchini, G., de Jong, E., de Kort, W., Duval-Modeste, A. -B., Fernandez Llaca, J. H., Gaastra, M., Ghislain, P. -D., Goujon, C., Griffiths, C., Horev-Yakir, L., Ioannidis, D., Izu, R., Krasagakis, K., Lacour, J-P., Lambert, J., Lopez Estebaranz, J. L., Malara, G., Markham, T., Matz, H., Mcbride, S., Moseng, D., Nikkels, A., Papakonstantis, M., Pavlotsky, F., Pavlovsky, L., Pellacani, G., Peserico, A., Piccirillo, Aniello, Potenza, C., Prignano, F., Puig Sanz, L., Raboobee, N., Rallis, E., Ramon, M., Reguiai, Z., Riedl, E., Ruer, M., Rustad, L., Salmhofer, W., Sanchez-Carazo, J. L., Schmutz, J. -L., Sokolovsky, E., Sotiriadis, D., Tobin, A. -M., Zhukova, O., Ziv, M., Amsterdam Movement Sciences - Restoration and Development, APH - Methodology, APH - Quality of Care, AII - Inflammatory diseases, and Dermatology

Subjects
Adult, Male, medicine.medical_specialty, Population, Dermatology, Hospital Anxiety and Depression Scale, Severity of Illness Index, disease burden, South Africa, 030207 dermatology & venereal diseases, 03 medical and health sciences, Toronto Alexithymia Scale, 0302 clinical medicine, Cost of Illness, Alexithymia, Risk Factors, Psoriasis Area and Severity Index, Internal medicine, Psoriasis, Prevalence, Humans, alexithymia, psoriasis, disease burden, Medicine, Affective Symptoms, Psychiatry, education, Disease burden, Psychiatric Status Rating Scales, education.field_of_study, medicine.diagnostic_test, business.industry, psoriasis, Dermatology Life Quality Index, medicine.disease, 030227 psychiatry, Europe, Case-Control Studies, Quality of Life, Female, alexithymia, business
Abstract

SummaryBackground Single-centre studies show that alexithymia, defined as difficulty in recognizing and describing emotions, is more prevalent among psoriasis patients than in the general population. However, its prevalence and the consequences of the association between alexithymia and psoriasis are unclear. Objectives The primary objective of this study was to determine the prevalence of alexithymia, as defined by a score ≥61 in the 20-item Toronto Alexithymia Scale (TAS-20), in a large sample of patients who had plaque psoriasis for ≤10 years and were eligible for phototherapy or systemic treatment. The secondary objectives were to investigate the relationship between alexithymia and the clinical and psychological aspects of psoriasis. Methods Data were collected in the framework of an observational, multicenter, international study, the EPidemiological Study In Patients With Recently DiagnosEd PSOriasis (EPIDEPSO), aiming at investigating the prevalence of alexithymia and other psychosocial comorbidities in psoriasis patients with ≤10 years disease duration. Results The prevalence of alexithymia within a cohort of 670 patients was 24.8% (95%CI: 21.7-28.2). Patients with alexithymia had a higher burden of psoriasis, including significant impairment of quality of life, higher levels of anxiety and depression, a higher risk of alcohol dependency and impairment of work productivity, compared to patients without alexithymia. Conclusion It is important to identify alexithymic patients with psoriasis in clinical practice as they suffer from a higher disease burden and have a lower ability to express their feelings. This article is protected by copyright. All rights reserved.

Published
2017
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