Search

Your search keyword '"de Hidru H.D."' showing total 5 results
Start Over Author "de Hidru H.D."
5 results on '"de Hidru H.D."'

1. Subnational mapping of HIV incidence and mortality among individuals aged 15-49 years in sub-Saharan Africa, 2000-18: a modelling study

Author

Sartorius, B., VanderHeide, J.D., Yang, M., Goosmann, E.A., Hon, J., Haeuser, E., Cork, M.A., Perkins, S., Jahagirdar, D., Schaeffer, L.E., Serfes, A.L., LeGrand, K.E., Abbastabar, H., Abebo, Z.H., Abosetugn, A.E., Abu-Gharbieh, E., Accrombessi, M.M.K., Adebayo, O.M., Adegbosin, A.E., Adekanmbi, V., Adetokunboh, O.O., Adeyinka, D.A., Ahinkorah, B.O., Ahmadi, K., Ahmed, M.B., Akalu, Y., Akinyemi, O.O., Akinyemi, R.O., Aklilu, A., Akunna, C.J., Alahdab, F., Al-Aly, Z., Alam, N., Alamneh, A.A., Alanzi, T.M., Alemu, B.W., Alhassan, R.K., Ali, T., Alipour, V., Amini, S., Ancuceanu, R., Ansari, F., Anteneh, Z.A., Anvari, D., Anwer, R., Appiah, S.C.Y., Arabloo, J., Asemahagn, M.A., Asghari Jafarabadi, M., Asmare, W.N., Atnafu, D.D., Atout, M.M.W., Atreya, A., Ausloos, M., Awedew, A.F., Ayala Quintanilla, B.P., Ayanore, M.A., Aynalem, Y.A., Ayza, M.A., Azari, S., Azene, Z.N., Babar, Z.-U.-D., Baig, A.A., Balakrishnan, S., Banach, M., Bärnighausen, T.W., Basu, S., Bayati, M., Bedi, N., Bekuma, T.T., Bezabhe, W.M.M., Bhagavathula, A.S., Bhardwaj, P., Bhattacharyya, K., Bhutta, Z.A., Bibi, S., Bikbov, B., Birhan, T.A., Bitew, Z.W., Bockarie, M.J., Boloor, A., Brady, O.J., Bragazzi, N.L., Briko, A.N., Briko, N.I., Burugina Nagaraja, S., Butt, Z.A., Cárdenas, R., Carvalho, F., Charan, J., Chatterjee, S., Chattu, S.K., Chattu, V.K., Chowdhury, M.A.K., Chu, D.-T., Cook, A.J., Cormier, N.M., Cowden, R.G., Culquichicon, C., Dagnew, B., Dahlawi, S.M.A., Damiani, G., Daneshpajouhnejad, P., Daoud, F., Daryani, A., das Neves, J., Davis Weaver, N., Derbew Molla, M., Deribe, K., Desta, A.A., Deuba, K., Dharmaratne, S.D., Dhungana, G.P., Diaz, D., Djalalinia, S., Doku, P.N., Dubljanin, E., Duko, B., Eagan, A.W., Earl, L., Eaton, J.W., Effiong, A., El Sayed Zaki, M., El Tantawi, M., Elayedath, R., El-Jaafary, S.I., Elsharkawy, A., Eskandarieh, S., Eyawo, O., Ezzikouri, S., Fasanmi, A.O., Fasil, A., Fauk, N.K., Feigin, V.L., Ferede, T.Y., Fernandes, E., Fischer, F., Foigt, N.A., Folayan, M.O., Foroutan, M., Francis, J.M., Fukumoto, T., Gad, M.M., Geberemariyam, B.S., Gebregiorgis, B., Gebremichael, B., Gesesew, H.A., Getacher, L., Ghadiri, K., Ghashghaee, A., Gilani, S.A., Ginindza, T.G., Glagn, M., Golechha, M., Gona, P.N., Gubari, M.I.M., Gugnani, H.C., Guido, D., Guled, R.A., Hall, B.J., Hamidi, S., Handiso, D.W., Hargono, A., Hashi, A., Hassanipour, S., Hassankhani, H., Hayat, K., Herteliu, C., de Hidru, H.D., Holla, R., Hosgood, H.D., Hossain, N., Hosseini, M., Hosseinzadeh, M., Househ, M., Hwang, B.-F., Ibitoye, S.E., Ilesanmi, O.S., Ilic, I.M., Ilic, M.D., Irvani, S.S.N., Iwu, C.C.D., Iwu, C.J., Iyamu, I.O., Jain, V., Jakovljevic, M., Jalilian, F., Jha, R.P., Johnson, K.B., Joshua, V., Joukar, F., Jozwiak, J.J., Kabir, A., Kalankesh, L.R., Kalhor, R., Kamath, A., Kamyari, N., Kanchan, T., Karami Matin, B., Karch, A., Karimi, S.E., Kasa, A.S., Kassahun, G., Kayode, G.A., Kazemi Karyani, A., Keiyoro, P.N., Kelkay, B., Khalid, N., Khan, G., Khan, J., Khan, M.N., Khatab, K., Khazaei, S., Kim, Y.J., Kisa, A., Kisa, S., Kochhar, S., Kopec, J.A., Kosen, S., Koulmane Laxminarayana, S., Koyanagi, A., Krishan, K., Kuate Defo, B., Kugbey, N., Kulkarni, V., Kumar, M., Kumar, N., Kurmi, O.P., Kusuma, D., Kuupiel, D., Kyu, H.H., La Vecchia, C., Lal, D.K., Lam, J.O., Landires, I., Lasrado, S., Lazarus, J.V., Lazzar-Atwood, A., Lee, P.H., Leshargie, C.T., Li, B., Liu, X., Lopukhov, P.D., Amin, H.I.M., Madi, D., Mahasha, P.W., Majeed, A., Maleki, A., Maleki, S., Mamun, A.A., Manafi, N., Mansournia, M.A., Martins-Melo, F.R., Masoumi, S.Z., Mayala, B.K., Meharie, B.G., Meheretu, H.A.A., Meles, H.G., Melku, M., Mendoza, W., Mengesha, E.W., Meretoja, T.J., Mersha, A.M., Mestrovic, T., Miller, T.R., Mirica, A., Mirzaei-Alavijeh, M., Mohamad, O., Mohammad, Y., Mohammadian-Hafshejani, A., Mohammed, J.A., Mohammed, S., Mokdad, A.H., Mokonnon, T., Molokhia, M., Moradi, M., Moradi, Y., Moradzadeh, R., Moraga, P., Mosser, J.F., Munro, S.B., Mustafa, G., Muthupandian, S., Naderi, M., Nagarajan, A.J., Naghavi, M., Naveed, M., Nayak, V.C., Nazari, J., Ndejjo, R., Nepal, S., Netsere, H.B., Ngalesoni, F.N., Nguefack-Tsague, G., Ngunjiri, J.W., Nigatu, Y.T., Nigussie, S.N., Nnaji, C.A., Noubiap, J.J., Nuñez-Samudio, V., Oancea, B., Odukoya, O.O., Ogbo, F.A., Oladimeji, O., Olagunju, A.T., Olusanya, B.O., Olusanya, J.O., Omer, M.O., Omonisi, A.E.E., Onwujekwe, O.E., Orisakwe, O.E., Otstavnov, N., Owolabi, M.O., Mahesh, P.A., Padubidri, J.R., Pakhale, S., Pana, A., Pandi-Perumal, S.R., Patel, U.K., Pathak, M., Patton, G.C., Pawar, S., Peprah, E.K., Pokhrel, K.N., Postma, M.J., Pottoo, F.H., Pourjafar, H., Pribadi, D.R.A., Quazi Syed, Z., Rafiei, A., Rahim, F., Rahman, M.H.U., Rahmani, A.M., Ram, P., Rana, J., Ranabhat, C.L., Rao, S., Rao, S.J., Rathi, P., Rawaf, D.L., Rawaf, S., Rawassizadeh, R., Renjith, V., Reta, M.A., Rezaei, N., Rezapour, A., Ribeiro, A.I., Ross, J.M., Rumisha, S.F., Sagar, R., Sahu, M., Sajadi, S.M., Salem, M.R., Samy, A.M., Sathian, B., Schutte, A.E., Seidu, A.-A., Sha, F., Shafaat, O., Shahbaz, M., Shaikh, M.A., Shaka, M.F., Sheikh, A., Shibuya, K., Shin, J.I., Shivakumar, K.M., Sidemo, N.B., Singh, J.A., Skryabin, V.Y., Skryabina, A.A., Soheili, A., Soltani, S., Somefun, O.D., Sorrie, M.B., Spurlock, E.E., Sufiyan, M.B., Taddele, B.W., Tadesse, E.G., Tamir, Z., Tamiru, A.T., Tanser, F.C., Taveira, N., Tehrani-Banihashemi, A., Tekalegn, Y., Tesfay, F.H., Tessema, B., Tessema, Z.T., Thakur, B., Tolani, M.A., Topor-Madry, R., Torrado, M., Tovani-Palone, M.R., Traini, E., Tsai, A.C., Tsegaye, G.W., Ullah, I., Ullah, S., Umeokonkwo, C.D., Unnikrishnan, B., Vardavas, C., Violante, F.S., Vo, B., Wado, Y.D., Waheed, Y., Wamai, R.G., Wang, Y., Ward, P., Werdecker, A., Wickramasinghe, N.D., Wijeratne, T., Wiysonge, C.S., Wondmeneh, T.G., Yamada, T., Yaya, S., Yeshaw, Y., Yeshitila, Y.G., Yilma, M.T., Yip, P., Yonemoto, N., Yosef, T., Yusefzadeh, H., Zaidi, S.S., Zaki, L., Zamanian, M., Zastrozhin, M.S., Zastrozhina, A., Zewdie, D.T., Zhang, Y., Zhang, Z.-J., Ziapour, A., Hay, S.I., Dwyer-Lindgren, L., LBD HIV Incidence Mortality Collaborators, Instituto de Saúde Pública da Universidade do Porto, Khatab, Khaled, Sartorius B., VanderHeide J.D., Yang M., Goosmann E.A., Hon J., Haeuser E., Cork M.A., Perkins S., Jahagirdar D., Schaeffer L.E., Serfes A.L., LeGrand K.E., Abbastabar H., Abebo Z.H., Abosetugn A.E., Abu-Gharbieh E., Accrombessi M.M.K., Adebayo O.M., Adegbosin A.E., Adekanmbi V., Adetokunboh O.O., Adeyinka D.A., Ahinkorah B.O., Ahmadi K., Ahmed M.B., Akalu Y., Akinyemi O.O., Akinyemi R.O., Aklilu A., Akunna C.J., Alahdab F., Al-Aly Z., Alam N., Alamneh A.A., Alanzi T.M., Alemu B.W., Alhassan R.K., Ali T., Alipour V., Amini S., Ancuceanu R., Ansari F., Anteneh Z.A., Anvari D., Anwer R., Appiah S.C.Y., Arabloo J., Asemahagn M.A., Asghari Jafarabadi M., Asmare W.N., Atnafu D.D., Atout M.M.W., Atreya A., Ausloos M., Awedew A.F., Ayala Quintanilla B.P., Ayanore M.A., Aynalem Y.A., Ayza M.A., Azari S., Azene Z.N., Babar Z.-U.-D., Baig A.A., Balakrishnan S., Banach M., Barnighausen T.W., Basu S., Bayati M., Bedi N., Bekuma T.T., Bezabhe W.M.M., Bhagavathula A.S., Bhardwaj P., Bhattacharyya K., Bhutta Z.A., Bibi S., Bikbov B., Birhan T.A., Bitew Z.W., Bockarie M.J., Boloor A., Brady O.J., Bragazzi N.L., Briko A.N., Briko N.I., Burugina Nagaraja S., Butt Z.A., Cardenas R., Carvalho F., Charan J., Chatterjee S., Chattu S.K., Chattu V.K., Chowdhury M.A.K., Chu D.-T., Cook A.J., Cormier N.M., Cowden R.G., Culquichicon C., Dagnew B., Dahlawi S.M.A., Damiani G., Daneshpajouhnejad P., Daoud F., Daryani A., das Neves J., Davis Weaver N., Derbew Molla M., Deribe K., Desta A.A., Deuba K., Dharmaratne S.D., Dhungana G.P., Diaz D., Djalalinia S., Doku P.N., Dubljanin E., Duko B., Eagan A.W., Earl L., Eaton J.W., Effiong A., El Sayed Zaki M., El Tantawi M., Elayedath R., El-Jaafary S.I., Elsharkawy A., Eskandarieh S., Eyawo O., Ezzikouri S., Fasanmi A.O., Fasil A., Fauk N.K., Feigin V.L., Ferede T.Y., Fernandes E., Fischer F., Foigt N.A., Folayan M.O., Foroutan M., Francis J.M., Fukumoto T., Gad M.M., Geberemariyam B.S., Gebregiorgis B., Gebremichael B., Gesesew H.A., Getacher L., Ghadiri K., Ghashghaee A., Gilani S.A., Ginindza T.G., Glagn M., Golechha M., Gona P.N., Gubari M.I.M., Gugnani H.C., Guido D., Guled R.A., Hall B.J., Hamidi S., Handiso D.W., Hargono A., Hashi A., Hassanipour S., Hassankhani H., Hayat K., Herteliu C., de Hidru H.D., Holla R., Hosgood H.D., Hossain N., Hosseini M., Hosseinzadeh M., Househ M., Hwang B.-F., Ibitoye S.E., Ilesanmi O.S., Ilic I.M., Ilic M.D., Irvani S.S.N., Iwu C.C.D., Iwu C.J., Iyamu I.O., Jain V., Jakovljevic M., Jalilian F., Jha R.P., Johnson K.B., Joshua V., Joukar F., Jozwiak J.J., Kabir A., Kalankesh L.R., Kalhor R., Kamath A., Kamyari N., Kanchan T., Karami Matin B., Karch A., Karimi S.E., Kasa A.S., Kassahun G., Kayode G.A., Kazemi Karyani A., Keiyoro P.N., Kelkay B., Khalid N., Khan G., Khan J., Khan M.N., Khatab K., Khazaei S., Kim Y.J., Kisa A., Kisa S., Kochhar S., Kopec J.A., Kosen S., Koulmane Laxminarayana S., Koyanagi A., Krishan K., Kuate Defo B., Kugbey N., Kulkarni V., Kumar M., Kumar N., Kurmi O.P., Kusuma D., Kuupiel D., Kyu H.H., La Vecchia C., Lal D.K., Lam J.O., Landires I., Lasrado S., Lazarus J.V., Lazzar-Atwood A., Lee P.H., Leshargie C.T., Li B., Liu X., Lopukhov P.D., Amin H.I.M., Madi D., Mahasha P.W., Majeed A., Maleki A., Maleki S., Mamun A.A., Manafi N., Mansournia M.A., Martins-Melo F.R., Masoumi S.Z., Mayala B.K., Meharie B.G., Meheretu H.A.A., Meles H.G., Melku M., Mendoza W., Mengesha E.W., Meretoja T.J., Mersha A.M., Mestrovic T., Miller T.R., Mirica A., Mirzaei-Alavijeh M., Mohamad O., Mohammad Y., Mohammadian-Hafshejani A., Mohammed J.A., Mohammed S., Mokdad A.H., Mokonnon T., Molokhia M., Moradi M., Moradi Y., Moradzadeh R., Moraga P., Mosser J.F., Munro S.B., Mustafa G., Muthupandian S., Naderi M., Nagarajan A.J., Naghavi M., Naveed M., Nayak V.C., Nazari J., Ndejjo R., Nepal S., Netsere H.B., Ngalesoni F.N., Nguefack-Tsague G., Ngunjiri J.W., Nigatu Y.T., Nigussie S.N., Nnaji C.A., Noubiap J.J., Nunez-Samudio V., Oancea B., Odukoya O.O., Ogbo F.A., Oladimeji O., Olagunju A.T., Olusanya B.O., Olusanya J.O., Omer M.O., Omonisi A.E.E., Onwujekwe O.E., Orisakwe O.E., Otstavnov N., Owolabi M.O., Mahesh P.A., Padubidri J.R., Pakhale S., Pana A., Pandi-Perumal S.R., Patel U.K., Pathak M., Patton G.C., Pawar S., Peprah E.K., Pokhrel K.N., Postma M.J., Pottoo F.H., Pourjafar H., Pribadi D.R.A., Quazi Syed Z., Rafiei A., Rahim F., Rahman M.H.U., Rahmani A.M., Ram P., Rana J., Ranabhat C.L., Rao S., Rao S.J., Rathi P., Rawaf D.L., Rawaf S., Rawassizadeh R., Renjith V., Reta M.A., Rezaei N., Rezapour A., Ribeiro A.I., Ross J.M., Rumisha S.F., Sagar R., Sahu M., Sajadi S.M., Salem M.R., Samy A.M., Sathian B., Schutte A.E., Seidu A.-A., Sha F., Shafaat O., Shahbaz M., Shaikh M.A., Shaka M.F., Sheikh A., Shibuya K., Shin J.I., Shivakumar K.M., Sidemo N.B., Singh J.A., Skryabin V.Y., Skryabina A.A., Soheili A., Soltani S., Somefun O.D., Sorrie M.B., Spurlock E.E., Sufiyan M.B., Taddele B.W., Tadesse E.G., Tamir Z., Tamiru A.T., Tanser F.C., Taveira N., Tehrani-Banihashemi A., Tekalegn Y., Tesfay F.H., Tessema B., Tessema Z.T., Thakur B., Tolani M.A., Topor-Madry R., Torrado M., Tovani-Palone M.R., Traini E., Tsai A.C., Tsegaye G.W., Ullah I., Ullah S., Umeokonkwo C.D., Unnikrishnan B., Vardavas C., Violante F.S., Vo B., Wado Y.D., Waheed Y., Wamai R.G., Wang Y., Ward P., Werdecker A., Wickramasinghe N.D., Wijeratne T., Wiysonge C.S., Wondmeneh T.G., Yamada T., Yaya S., Yeshaw Y., Yeshitila Y.G., Yilma M.T., Yip P., Yonemoto N., Yosef T., Yusefzadeh H., Zaidi S.S., Zaki L., Zamanian M., Zastrozhin M.S., Zastrozhina A., Zewdie D.T., Zhang Y., Zhang Z.-J., Ziapour A., Hay S.I., Dwyer-Lindgren L., Local Burden of Disease HIV Collaborators, Duko, Bereket, Yeshaw, Yigizie, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE), Microbes in Health and Disease (MHD), Bill & Melinda Gates Foundation, HUS Comprehensive Cancer Center, and Clinicum

Subjects
0301 basic medicine, sub-Saharan Africa, Male, HIV Antibodie, Epidemiology, HIV incidences, HIV Infections, mortality rate, HIV Antibodies, Modelling study, Human immunodeficiency virus prevalence, 0302 clinical medicine, Africa, Northern, RA0421, Seroepidemiologic Studies, Medicine, Northern, HIV Infection, 030212 general & internal medicine, Young adult, 10. No inequality, uncertainty, Mozambique, 11 Medical and Health Sciences, HIV mortality, Mortality rate, Incidence (epidemiology), Incidence, 1. No poverty, Hiv incidence, article, Mauritania, Human immunodeficiency virus infected patient, Articles, tracking, Middle Aged, health care planning, 3. Good health, Lesotho, AIDS, Infectious Diseases, QR180, A990 Medicine and Dentistry not elsewhere classified, Female, prenatal care, anti human immunodeficiency virus agent, seroepidemiology, Human, Adult, Adolescent, Anti-HIV Agents, Immunology, antiretroviral therapy, Unit (housing), 03 medical and health sciences, Young Adult, blood, Human immunodeficiency virus infection, Virology, Seroprevalence, Humans, human, Developing Countries, Estimation, Acquired Immunodeficiency Syndrome, Subnational mappings, business.industry, Seroepidemiologic Studie, HIV, Anti-HIV Agent, PREVENTION, 030112 virology, mortality, monitoring, 3121 General medicine, internal medicine and other clinical medicine, Human immunodeficiency virus antibody, Africa, business, HIV incidence, Subnational mapping, Sub-Saharan Africa, Local burden of disease, Public health, Demography
Abstract

Background. High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. Methods. In this modelling study, we developed a framework that used the geographically specific HIV prevalence data collected in seroprevalence surveys and antenatal care clinics to train a model that estimates HIV incidence and mortality among individuals aged 15–49 years. We used a model-based geostatistical framework to estimate HIV prevalence at the second administrative level in 44 countries in sub-Saharan Africa for 2000–18 and sought data on the number of individuals on antiretroviral therapy (ART) by second-level administrative unit. We then modified the Estimation and Projection Package (EPP) to use these HIV prevalence and treatment estimates to estimate HIV incidence and mortality by second-level administrative unit. Findings. The estimates suggest substantial variation in HIV incidence and mortality rates both between and within countries in sub-Saharan Africa, with 15 countries having a ten-times or greater difference in estimated HIV incidence between the second-level administrative units with the lowest and highest estimated incidence levels. Across all 44 countries in 2018, HIV incidence ranged from 2·8 (95% uncertainty interval 2·1–3·8) in Mauritania to 1585·9 (1369·4–1824·8) cases per 100 000 people in Lesotho and HIV mortality ranged from 0·8 (0·7–0·9) in Mauritania to 676·5 (513·6–888·0) deaths per 100 000 people in Lesotho. Variation in both incidence and mortality was substantially greater at the subnational level than at the national level and the highest estimated rates were accordingly higher. Among second-level administrative units, Guijá District, Gaza Province, Mozambique, had the highest estimated HIV incidence (4661·7 [2544·8–8120·3]) cases per 100 000 people in 2018 and Inhassunge District, Zambezia Province, Mozambique, had the highest estimated HIV mortality rate (1163·0 [679·0–1866·8]) deaths per 100 000 people. Further, the rate of reduction in HIV incidence and mortality from 2000 to 2018, as well as the ratio of new infections to the number of people living with HIV was highly variable. Although most second-level administrative units had declines in the number of new cases (3316 [81·1%] of 4087 units) and number of deaths (3325 [81·4%]), nearly all appeared well short of the targeted 75% reduction in new cases and deaths between 2010 and 2020. Interpretation. Our estimates suggest that most second-level administrative units in sub-Saharan Africa are falling short of the targeted 75% reduction in new cases and deaths by 2020, which is further compounded by substantial within-country variability. These estimates will help decision makers and programme implementers expand access to ART and better target health resources to higher burden subnational areas. This work was primarily supported by the Bill & Melinda Gates Foundation (grant OPP1132415). Additionally, O Adetokunboh acknowledges the support of the Department of Science and Innovation, and National Research Foundation of South Africa. M Ausloos, A Pana, and C Herteliu are partially supported by a grant of the Romanian National Authority for Scientific Research and Innovation, Executive Agency for Higher Education, Research, Development and Innovation Funding (Romania; project number PN-III-P4-ID-PCCF-2016-0084). T W Bärnighausen was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, funded by the German Federal Ministry of Education and Research. M J Bockarie is supported by the European and Developing Countries Clinical Trials Partnership. F Carvalho and E Fernandes acknowledge support from Portuguese national funds (Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior; UIDB/info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB/50006/2020/PT, UIDB/04378/2020, and UIDP/04378/2020. K Deribe is supported by the Wellcome Trust (grant 201900/Z/16/Z) as part of his International Intermediate Fellowship. B-F Hwang was partially supported by China Medical University (CMU107-Z-04), Taichung, Taiwan. M Jakovljevic acknowledges support of the Serbia Ministry of Education Science and Technological Development (grant OI 175 014). M N Khan acknowledges the support of Jatiya Kabi Kazi Nazrul Islam University, Bangladesh. Y J Kim was supported by the Research Management Centre, Xiamen University Malaysia, Malaysia, (XMUMRF/2020-C6/ITCM/0004). K Krishnan is supported by University Grants Commission Centre of Advanced Study, (CAS II), awarded to the Department of Anthropology, Panjab University, Chandigarh, India. M Kumar would like to acknowledge National Institutes of Health and Fogarty International Cente (K43TW010716). I Landires is a member of the Sistema Nacional de Investigación, which is supported by the Secretaría Nacional de Ciencia, Tecnología e Innovación, Panama. W Mendoza is a program analyst in population and development at the UN Population Fund Country Office in Peru, which does not necessarily endorse this study. M Phetole received institutional support from the Grants, Innovation and Product Development Unit, South African Medical Research Council. O Odukoya acknowledges support from the Fogarty International Center of the US National Institutes of Health (K43TW010704). The content is solely the responsibility of the authors and does not necessarily represent the official views of the US National Institutes of Health. O Oladimeji is grateful for the support from Walter Sisulu University, Eastern Cape, South Africa, the University of Botswana, Botswana, and the University of Technology of Durban, Durban, South Africa. J R Padubidri acknowledges support from Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, India. G C Patton is supported by an Australian Government National Health and Medical Research Council research fellowship. P Rathi acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal India. A I Ribeiro was supported by National Funds through Fundação para a Ciência e Tecnologia, under the programme of Stimulus of Scientific Employment–Individual Support (info:eu-repo/grantAgreement/FCT/CEEC IND 2018/CEECIND/02386/2018/CP1538/CT0001/PT). A M Samy acknowledges the support of the Egyptian Fulbright Mission Program. F Sha was supported by the Shenzhen Social Science Fund (SZ2020C015) and the Shenzhen Science and Technology Program (KQTD20190929172835662). A Sheikh is supported by Health Data Research UK. N Taveira acknowledges partial funding by Fundação para a Ciência e Tecnologia, Portugal, and Aga Khan Development Network—Portugal Collaborative Research Network in Portuguese-speaking countries in Africa (332821690), and by the European and Developing Countries Clinical Trials Partnership (RIA2016MC-1615). C S Wiysonge is supported by the South African Medical Research Council. Y Zhang was supported by the Science and Technology Research Project of Hubei Provincial Department of Education (Q20201104) and Open Fund Project of Hubei Province Key Laboratory of Occupational Hazard Identification and Control (OHIC2020Y01).

Published
2021

2. Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning.

Author

Cromwell E.A., Osborne J.C.P., Unnasch T.R., Basanez M., Gass K.M., Barbre K.A., Hill E., Johnson K.B., Donkers K.M., Shirude S., Schmidt C.A., Adekanmbi V., Adetokunboh O.O., Afarideh M., Ahmadpour E., Beshir Ahmed M., Yihunie Akalu T., Al-Aly Z., Alanezi F.M., Alanzi T.M., Alipour V., Andrei C.L., Ansari F., Ansha M.G., Anvari D., Yaw Appiah S.C., Arabloo J., Arnold B.F., Ausloos M., Ayanore M.A., Amin Baig A., Banach M., Barac A., Barnighausen T.W., Bayati M., Bhattacharyya K., Bhutta Z.A., Bibi S., Bijani A., Bohlouli S., Bohluli M., Brady O.J., Bragazzi N.L., Butt Z.A., Carvalho F., Chatterjee S., Chattu V.K., Chattu S.K., Cormier N.M., Dahlawi S.M.A., Damiani G., Daoud F., Darwesh A.M., Daryani A., Deribe K., Dharmaratne S.D., Diaz D., Do H.T., El Sayed Zak M., El Tantawi M., Elemineh D.A., Faraj A., Harandi M.F., Fatahi Y., Feigin V.L., Fernandes E., Foigt N.A., Foroutan M., Franklin R.C., Mohialdeen Gubari M.I., Guido D., Guo Y., Haj-Mirzaian A., Abdullah K.H., Hamidi S., Herteliu C., De Hidru H.D., Higazi T.B., Hossain N., Hosseinzadeh M., Househ M., Ilesanmi O.S., Ilic M.D., Ilic I.M., Iqbal U., Naghibi Irvani S.S., Jha R.P., Joukar F., Jozwiak J.J., Kabir Z., Kalankesh L.R., Kalhor R., Matin B.K., Karimi S.E., Kasaeian A., Kavetskyy T., Kayode G.A., Karyani A.K., Kelbore A.G., Keramati M., Khalilov R., Khan E.A., Nuruzzaman Khan M.N., Khatab K., Khater M.M., Kianipour N., Kibret K.T., Kim Y.J., Kosen S., Krohn K.J., Kusuma D., Vecchia C.L., Lansingh V.C., Lee P.H., Legrand K.E., Li S., Longbottom J., Abd El Razek H.M., Abd El Razek M.M., Maleki A., Mamun A.A., Manafi A., Manafi N., Mansournia M.A., Martins-Melo F.R., Mazidi M., McAlinden C., Meharie B.G., Mendoza W., Mengesha E.W., Mengistu D.T., Mereta S.T., Mestrovic T., Miller T.R., Miri M., Moghadaszadeh M., Hafshejani A.M., Mohammadpourhodki R., Mohammed S., Moradi M., Moradzadeh R., Moraga P., Mosser J.F., Naderi M., Nagarajan A.J., Naik G., Negoi I., Nguyen C.T., Nguyen H.L.T., Nguyen T.H., Nikbakhsh R., Oancea B., Olagunju T.O., Olagunju A.T., Bali A.O., Onwujekwe O.E., Pana A., Pourjafar H., Rahim F., Ur Rahman M.H., Rathi P., Rawaf S., Rawaf D.L., Rawassizadeh R., Resnikoff S., Reta M.A., Rezapour A., Rubagotti E., Rubino S., Sadeghi E., Saghafipour A., Sajadi S.M., Samy A.M., Sarmiento-Suarez R., Sawhney M., Schipp M.F., Shaheen A.A., Shaikh M.A., Shamsizadeh M., Sharafi K., Sheikh A., Kumar Shetty B.S., Shin J.I., Shivakumar K.M., Simonetti B., Singh J.A., Skiadaresi E., Soheili A., Soltani S., Spurlock E.E., Sufiyan M.B., Tabuchi T., Tapak L., Thompson R.L., Thomson A.J., Traini E., Tran B.X., Ullah I., Ullah S., Uneke C.J., Unnikrishnan B., Uthman O.A., Melchers N.V.S.V., Violante F.S., Wolde H.F., Wonde T.E., Yamada T., Yaya S., Yazdi Feyzabadi V., Yip P., Yonemoto N., Yousof H.-A.S.A., Yu C., Yu Y., Yusefzadeh H., Zaki L., Zaman S.B., Zamanian M., Zhang Z.-J., Zhang Y., Ziapour A., Hay S.I., Pigott D.M., Cromwell E.A., Osborne J.C.P., Unnasch T.R., Basanez M., Gass K.M., Barbre K.A., Hill E., Johnson K.B., Donkers K.M., Shirude S., Schmidt C.A., Adekanmbi V., Adetokunboh O.O., Afarideh M., Ahmadpour E., Beshir Ahmed M., Yihunie Akalu T., Al-Aly Z., Alanezi F.M., Alanzi T.M., Alipour V., Andrei C.L., Ansari F., Ansha M.G., Anvari D., Yaw Appiah S.C., Arabloo J., Arnold B.F., Ausloos M., Ayanore M.A., Amin Baig A., Banach M., Barac A., Barnighausen T.W., Bayati M., Bhattacharyya K., Bhutta Z.A., Bibi S., Bijani A., Bohlouli S., Bohluli M., Brady O.J., Bragazzi N.L., Butt Z.A., Carvalho F., Chatterjee S., Chattu V.K., Chattu S.K., Cormier N.M., Dahlawi S.M.A., Damiani G., Daoud F., Darwesh A.M., Daryani A., Deribe K., Dharmaratne S.D., Diaz D., Do H.T., El Sayed Zak M., El Tantawi M., Elemineh D.A., Faraj A., Harandi M.F., Fatahi Y., Feigin V.L., Fernandes E., Foigt N.A., Foroutan M., Franklin R.C., Mohialdeen Gubari M.I., Guido D., Guo Y., Haj-Mirzaian A., Abdullah K.H., Hamidi S., Herteliu C., De Hidru H.D., Higazi T.B., Hossain N., Hosseinzadeh M., Househ M., Ilesanmi O.S., Ilic M.D., Ilic I.M., Iqbal U., Naghibi Irvani S.S., Jha R.P., Joukar F., Jozwiak J.J., Kabir Z., Kalankesh L.R., Kalhor R., Matin B.K., Karimi S.E., Kasaeian A., Kavetskyy T., Kayode G.A., Karyani A.K., Kelbore A.G., Keramati M., Khalilov R., Khan E.A., Nuruzzaman Khan M.N., Khatab K., Khater M.M., Kianipour N., Kibret K.T., Kim Y.J., Kosen S., Krohn K.J., Kusuma D., Vecchia C.L., Lansingh V.C., Lee P.H., Legrand K.E., Li S., Longbottom J., Abd El Razek H.M., Abd El Razek M.M., Maleki A., Mamun A.A., Manafi A., Manafi N., Mansournia M.A., Martins-Melo F.R., Mazidi M., McAlinden C., Meharie B.G., Mendoza W., Mengesha E.W., Mengistu D.T., Mereta S.T., Mestrovic T., Miller T.R., Miri M., Moghadaszadeh M., Hafshejani A.M., Mohammadpourhodki R., Mohammed S., Moradi M., Moradzadeh R., Moraga P., Mosser J.F., Naderi M., Nagarajan A.J., Naik G., Negoi I., Nguyen C.T., Nguyen H.L.T., Nguyen T.H., Nikbakhsh R., Oancea B., Olagunju T.O., Olagunju A.T., Bali A.O., Onwujekwe O.E., Pana A., Pourjafar H., Rahim F., Ur Rahman M.H., Rathi P., Rawaf S., Rawaf D.L., Rawassizadeh R., Resnikoff S., Reta M.A., Rezapour A., Rubagotti E., Rubino S., Sadeghi E., Saghafipour A., Sajadi S.M., Samy A.M., Sarmiento-Suarez R., Sawhney M., Schipp M.F., Shaheen A.A., Shaikh M.A., Shamsizadeh M., Sharafi K., Sheikh A., Kumar Shetty B.S., Shin J.I., Shivakumar K.M., Simonetti B., Singh J.A., Skiadaresi E., Soheili A., Soltani S., Spurlock E.E., Sufiyan M.B., Tabuchi T., Tapak L., Thompson R.L., Thomson A.J., Traini E., Tran B.X., Ullah I., Ullah S., Uneke C.J., Unnikrishnan B., Uthman O.A., Melchers N.V.S.V., Violante F.S., Wolde H.F., Wonde T.E., Yamada T., Yaya S., Yazdi Feyzabadi V., Yip P., Yonemoto N., Yousof H.-A.S.A., Yu C., Yu Y., Yusefzadeh H., Zaki L., Zaman S.B., Zamanian M., Zhang Z.-J., Zhang Y., Ziapour A., Hay S.I., and Pigott D.M.

Abstract

Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 x 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitability concordant with locations where onchocerciasis has been previously detected. This threshold value was then used to classify IUs (more suitable or less suitable) based on the location within the IU with the largest mean prediction. Mean estimates of environmental suitability suggest large areas across West and Central Africa, as well as focal areas of East Africa, are suitable for onchocerciasis transmission, consistent with the presence of current control and elimination of transmission efforts. The ROC analysis identified a mean environmental suitability index of 0.71 as a threshold to classify based on the location with the largest mean prediction within the IU. Of the IUs considered for mapping surveys, 50.2% exceed this threshold for suitability in at least one 5x5-km location. The formidable scale of data collection required to map onchocerciasis endemicity across the African continent presents an opportunity to use spatial data to identify areas likely to be suitable for onchocerciasis transmission. National onchocerciasis elimination programmes may wish to consider prioritising these IUs for mapping surveys as human resources, laboratory capacity, and programmatic schedules may constrain survey implementation, and possibly delaying MDA initiation in areas that would ult

Published
2021

3. The global distribution of lymphatic filariasis, 2000-18: a geospatial analysis.

Author

Hole M.K., Ilic M.D., Iqbal U., Irvani S.S.N., Islam S.M.S., Jha R.P., Ji J.S., Jozwiak J.J., Kabir A., Kalankesh L.R., Kalhor R., Karami Matin B., Karch A., Karimi S., Kasaeian A., Kazemi Karyani A., Kayode G.A., Kelbore A.G., Khafaie M.A., Khalilov R., Khan J., Khatab K., Khater M.M., Khodayari M., Kim Y.J., King J.D., Kinyoki D.K., Kianipour N., Kumar G.A., Kusuma D., La Vecchia C., Lansingh V.C., Lee P.H., LeGrand K.E., Levine A.J., Li S., Maleki S., Mansournia M.A., Martins-Melo F.R., Massenburg B.B., Mayala B.K., Meitei W.B., Mendoza W., Mengistu D.T., Mereta S.T., Mestrovic T., Mihretie K.M., Mohammadian-Hafshejani A., Mohammed S., Mokdad A.H., Moradi M., Moradzadeh R., Moraga P., Morrison S.D., Mosser J.F., Mousavi S.M., Munro S.B., Mupfasoni D., Muthupandian S., mwingira U.J., Naderi M., Nagarajan A.J., Naik G., Negoi I., Nguyen H.L.T., Nguyen T.H., Olagunju A.T., Omar Bali A., Osarenotor O., Osei F.B., Pasupula D., Pigott D.M., Shirude S., Hill E., Donkers K.M., Pirsaheb M., Pourjafar H., Rawaf S., Rawaf D.L., Rawassizadeh R., Reta M.A., Ribeiro A.I., Rostami A., Sabesan S., Sadeghi E., Sajadi S.M., Samy A.M., Sartorius B., Schaeffer L.E., Shaikh M.A., Sharafi K., Soltani S., Sharifi H., Shibuya K., Shin J.I., Soheili A., Spotin A., Stolk W.A., Tesfay B.E., Topor-Madry R., Tran B.X., Tran K.B., Ullah I., Unnikrishnan B., Vasseghian Y., Violante F.S., Vinkeles Melchers N.V.S., Yamada T., Yaya S., Yazdi-Feyzabadi V., Yip P., Yonemoto N., Zaki L., Zaman S.B., Zamanian M., Zangeneh A., Zhang Y., Zhang Z., Ziapour A., Hay S.I., Reiner R.C., Deshpande A., Miller-Petrie M.K., Johnson K.B., Abdoli A., Abrigo M.R.M., Adekanmbi V., Adetokunboh O.O., Adinarayanan S., Ahmadpour E., Ahmed M.B., Akalu T.Y., Alanezi T.M., Alinia C., Alipour V., Amit A.M.L., Anber N.H., Ancuceanu R., Andualem Z., Ansari F., Antonio C.A.T., Anvari D., Appiah S., Arabloo J., Arnold B.F., Ausloos M., Ayanore M.A., Badirzadeh A., Baig A.A., Banach M., Baraki A.G., Barnighausen T.W., Bayati M., Bhattacharyya K., Bhutta Z.A., Bijani A., Bockarie M.J., Bisanzio D., Biswas R.K., Bohlouli S., Cano J., Carvalho F., Chattu V.K., Chavshin C., Cormier N.M., Cromwell E.A., Schmidt C.A., Kwong K.T., Damiani G., Dandona R., Dandona L., Darwesh A.M., Daryani A., Dash A.P., Deribe K., Dessu B., Dhimal M., Dianatinasab M., Diaz D., Do H.T., Earl L., El Tantawi M., Faraj A., Fattahi N., Fernandes E., Fischer F., Foigt N.A., Foroutan M., Guo Y., Hailu G.B., Hasaballah A.I., Hassankhani H., Herteliu C., de Hidru H.D., Hon J., Hossain N., Hosseinzadeh M., Househ M., Humayun A., Ilesanmi O.S., Hole M.K., Ilic M.D., Iqbal U., Irvani S.S.N., Islam S.M.S., Jha R.P., Ji J.S., Jozwiak J.J., Kabir A., Kalankesh L.R., Kalhor R., Karami Matin B., Karch A., Karimi S., Kasaeian A., Kazemi Karyani A., Kayode G.A., Kelbore A.G., Khafaie M.A., Khalilov R., Khan J., Khatab K., Khater M.M., Khodayari M., Kim Y.J., King J.D., Kinyoki D.K., Kianipour N., Kumar G.A., Kusuma D., La Vecchia C., Lansingh V.C., Lee P.H., LeGrand K.E., Levine A.J., Li S., Maleki S., Mansournia M.A., Martins-Melo F.R., Massenburg B.B., Mayala B.K., Meitei W.B., Mendoza W., Mengistu D.T., Mereta S.T., Mestrovic T., Mihretie K.M., Mohammadian-Hafshejani A., Mohammed S., Mokdad A.H., Moradi M., Moradzadeh R., Moraga P., Morrison S.D., Mosser J.F., Mousavi S.M., Munro S.B., Mupfasoni D., Muthupandian S., mwingira U.J., Naderi M., Nagarajan A.J., Naik G., Negoi I., Nguyen H.L.T., Nguyen T.H., Olagunju A.T., Omar Bali A., Osarenotor O., Osei F.B., Pasupula D., Pigott D.M., Shirude S., Hill E., Donkers K.M., Pirsaheb M., Pourjafar H., Rawaf S., Rawaf D.L., Rawassizadeh R., Reta M.A., Ribeiro A.I., Rostami A., Sabesan S., Sadeghi E., Sajadi S.M., Samy A.M., Sartorius B., Schaeffer L.E., Shaikh M.A., Sharafi K., Soltani S., Sharifi H., Shibuya K., Shin J.I., Soheili A., Spotin A., Stolk W.A., Tesfay B.E., Topor-Madry R., Tran B.X., Tran K.B., Ullah I., Unnikrishnan B., Vasseghian Y., Violante F.S., Vinkeles Melchers N.V.S., Yamada T., Yaya S., Yazdi-Feyzabadi V., Yip P., Yonemoto N., Zaki L., Zaman S.B., Zamanian M., Zangeneh A., Zhang Y., Zhang Z., Ziapour A., Hay S.I., Reiner R.C., Deshpande A., Miller-Petrie M.K., Johnson K.B., Abdoli A., Abrigo M.R.M., Adekanmbi V., Adetokunboh O.O., Adinarayanan S., Ahmadpour E., Ahmed M.B., Akalu T.Y., Alanezi T.M., Alinia C., Alipour V., Amit A.M.L., Anber N.H., Ancuceanu R., Andualem Z., Ansari F., Antonio C.A.T., Anvari D., Appiah S., Arabloo J., Arnold B.F., Ausloos M., Ayanore M.A., Badirzadeh A., Baig A.A., Banach M., Baraki A.G., Barnighausen T.W., Bayati M., Bhattacharyya K., Bhutta Z.A., Bijani A., Bockarie M.J., Bisanzio D., Biswas R.K., Bohlouli S., Cano J., Carvalho F., Chattu V.K., Chavshin C., Cormier N.M., Cromwell E.A., Schmidt C.A., Kwong K.T., Damiani G., Dandona R., Dandona L., Darwesh A.M., Daryani A., Dash A.P., Deribe K., Dessu B., Dhimal M., Dianatinasab M., Diaz D., Do H.T., Earl L., El Tantawi M., Faraj A., Fattahi N., Fernandes E., Fischer F., Foigt N.A., Foroutan M., Guo Y., Hailu G.B., Hasaballah A.I., Hassankhani H., Herteliu C., de Hidru H.D., Hon J., Hossain N., Hosseinzadeh M., Househ M., Humayun A., and Ilesanmi O.S.

Abstract

Background: Lymphatic filariasis is a neglected tropical disease that can cause permanent disability through disruption of the lymphatic system. This disease is caused by parasitic filarial worms that are transmitted by mosquitos. Mass drug administration (MDA) of antihelmintics is recommended by WHO to eliminate lymphatic filariasis as a public health problem. This study aims to produce the first geospatial estimates of the global prevalence of lymphatic filariasis infection over time, to quantify progress towards elimination, and to identify geographical variation in distribution of infection. Method(s): A global dataset of georeferenced surveyed locations was used to model annual 2000-18 lymphatic filariasis prevalence for 73 current or previously endemic countries. We applied Bayesian model-based geostatistics and time series methods to generate spatially continuous estimates of global all-age 2000-18 prevalence of lymphatic filariasis infection mapped at a resolution of 5 km2 and aggregated to estimate total number of individuals infected. Finding(s): We used 14 927 datapoints to fit the geospatial models. An estimated 199 million total individuals (95% uncertainty interval 174-234 million) worldwide were infected with lymphatic filariasis in 2000, with totals for WHO regions ranging from 3.1 million (1.6-5.7 million) in the region of the Americas to 107 million (91-134 million) in the South-East Asia region. By 2018, an estimated 51 million individuals (43-63 million) were infected. Broad declines in prevalence are observed globally, but focal areas in Africa and southeast Asia remain less likely to have attained infection prevalence thresholds proposed to achieve local elimination. Interpretation(s): Although the prevalence of lymphatic filariasis infection has declined since 2000, MDA is still necessary across large populations in Africa and Asia. Our mapped estimates can be used to identify areas where the probability of meeting infection thresholds is low

Published
2020

4. Mapping inequalities in exclusive breastfeeding in low- and middle-income countries, 2000-2018

Author

Bhattacharjee, NV, Schaeffer, LE, Hay, SI, Lu, D, Schipp, MF, Lazzar-Atwood, A, Donkers, KM, Abady, GG, Abd-Allah, F, Abdelalim, A, Abebo, ZH, Abejie, AN, Abosetugn, AE, Abreu, LG, Abrigo, MRM, Abu-Gharbieh, E, Abushouk, AI, Adamu, AL, Adedeji, IA, Adegbosin, AE, Adekanmbi, V, Adetokunboh, OO, Agudelo-Botero, M, Aji, B, Akinyemi, OO, Alamneh, AA, Alanezi, FM, Alanzi, TM, Albright, J, Alcalde-Rabanal, JE, Alemu, BW, Alhassan, RK, Ali, BA, Ali, S, Alinia, C, Alipour, V, Amit, AML, Amugsi, DA, Anbesu, EW, Ancuceanu, R, Anjomshoa, M, Ansari, F, Antonio, CAT, Anvari, D, Arabloo, J, Arora, A, Artanti, KD, Asemahagn, MA, Asmare, WN, Atout, MMW, Ausloos, M, Awoke, N, Quintanilla, BPA, Ayanore, MA, Aynalem, YA, Ayza, MA, Azene, ZN, Darshan, BB, Badiye, AD, Baig, AA, Bakkannavar, SM, Banach, M, Banik, PC, Bärnighausen, TW, Basaleem, H, Bayati, M, Baye, BA, Bedi, N, Belay, SA, Bhagavathula, AS, Bhandari, D, Bhardwaj, N, Bhardwaj, P, Bhutta, ZA, Bijani, A, Birhan, TA, Birihane, BM, Bitew, ZW, Bohlouli, S, Bohluli, M, Bojia, HA, Boloor, A, Brady, OJ, Bragazzi, NL, Brunoni, AR, Budhathoki, SS, Nagaraja, SB, Butt, ZA, Cárdenas, R, Castaldelli-Maia, JM, Castro, F, Cernigliaro, A, Charan, J, Chatterjee, P, Chatterjee, S, Chattu, VK, Chaturvedi, S, Chowdhury, MAK, Chu, D-T, Collison, ML, Cook, AJ, Cork, MA, Couto, RAS, Dagnew, B, Dai, H, Dandona, L, Dandona, R, Daneshpajouhnejad, P, Darwesh, AM, Darwish, AH, Daryani, A, Das, JK, Gupta, RD, Dávila-Cervantes, CA, Davis, AC, Weaver, ND, Denova-Gutiérrez, E, Deribe, K, Desalew, A, Deshpande, A, Dessie, A, Deuba, K, Dharmaratne, SD, Dhimal, M, Dhungana, GP, Diaz, D, Didarloo, A, Dipeolu, IO, Doan, LP, Duko, B, Duraes, AR, Dwyer-Lindgren, L, Earl, L, Zaki, MES, Tantawi, ME, Elema, TB, Elhabashy, HR, El-Jaafary, SI, Faris, PS, Faro, A, Farzadfar, F, Feigin, VL, Feleke, BE, Ferede, TY, Fischer, F, Foigt, NA, Folayan, MO, Franklin, RC, Gad, MM, Gaidhane, S, Gardner, WM, Geberemariyam, BS, Gebregiorgis, BG, Gebremedhin, KB, Gebremichael, B, Ghaffarpasand, F, Gilani, SA, Ginindza, TG, Glagn, M, Golechha, M, Gonfa, KB, Goulart, BNG, Gudi, N, Guido, D, Guled, RA, Guo, Y, Hamidi, S, Handiso, DW, Hasaballah, AI, Hassan, A, Hayat, K, Hegazy, MI, Heidari, B, Henry, NJ, Herteliu, C, de, Hidru, HD, Ho, HC, Hoang, CL, Holla, R, Hon, J, Hosseini, M, Hosseinzadeh, M, Househ, M, Hsairi, M, Hu, G, Huda, TM, Hwang, B-F, Ibitoye, SE, Ilesanmi, OS, Ilic, IM, Ilic, MD, Inbaraj, LR, Iqbal, U, Irvani, SSN, Islam, MM, Iwu, CCD, Iwu, CJ, Jain, A, Janodia, MD, Javaheri, T, John-Akinola, YO, Johnson, KB, Joukar, F, Jozwiak, JJ, Kabir, A, Kalankesh, LR, Kalhor, R, Kamath, A, Kamyari, N, Kanchan, OT, Kapoor, N, Matin, BK, Karimi, SE, Kasaye, HK, Kassahun, G, Kassebaum, NJ, Kayode, GA, Karyani, AK, Keiyoro, PN, Kelkay, B, Khalid, N, Khan, MN, Khatab, K, Khater, AM, Khater, MM, Khatib, MN, Kim, YJ, Kimokoti, RW, Kinyoki, DK, Kisa, A, Kisa, S, Kosen, S, Krishan, K, Kulkarni, V, Kumar, GA, Kumar, M, Kumar, N, Kumar, P, Kurmi, OP, Kusuma, D, Vecchia, CL, Lad, SD, Lami, FH, Landires, I, Lansingh, VC, Lasrado, S, Lee, PH, LeGrand, KE, Letourneau, ID, Lewycka, S, Li, B, Li, M-C, Li, S, Liu, X, Lodha, R, Lopez, JCF, Louie, C, Machado, DB, Maled, V, Maleki, S, Malta, DC, Mamun, AA, Manafi, N, Mansournia, MA, Mapoma, CC, Marczak, LB, Martins-Melo, FR, Mehndiratta, MM, Mejia-Rodriguez, F, Mekonnen, TC, Mendoza, W, Menezes, RG, Mengesha, EW, Mersha, AM, Miller, TR, Mini, GK, Mirrakhimov, EM, Misra, S, Moghadaszadeh, M, Mohammad, DK, Mohammadian-Hafshejani, A, Mohammed, JA, Mohammed, S, Mokdad, AH, Montero-Zamora, PA, Moradi, M, Moradzadeh, R, Moraga, P, Mosser, JF, Mousavi, SM, Khaneghah, AM, Munro, SB, Muriithi, MK, Mustafa, G, Muthupandian, S, Nagarajan, AJ, Naik, G, Naimzada, MD, Nangia, V, Nascimento, BR, Nayak, VC, Ndejjo, R, Ndwandwe, DE, Negoi, I, Nguefack-Tsague, G, Ngunjiri, JW, Nguyen, CT, Nguyen, DN, Nguyen, HLT, Nigussie, SN, Nigussie, TTN, Nikbakhsh, R, Nnaji, CA, Nunez-Samudio, V, Oancea, B, Oghenetega, OB, Olagunju, AT, Olusanya, BO, Olusanya, JO, Omer, MO, Onwujekwe, OE, Ortega-Altamirano, DV, Osgood-Zimmerman, AE, Otstavnov, N, Otstavnov, SS, Owolabi, MO, Mahesh, PA, Padubidri, JR, Pana, A, Pandey, A, Pandi-Perumal, SR, Pangaribuan, HU, Parsekar, SS, Pasupula, DK, Patel, UK, Pathak, A, Pathak, M, Pattanshetty, SM, Patton, GC, Paulos, K, Pepito, VCF, Pickering, BV, Pinheiro, M, Piwoz, EG, Pokhrel, KN, Pourjafar, H, Prada, SI, Pribadi, DRA, Syed, ZQ, Rabiee, M, Rabiee, N, Rahim, F, Rahimzadeh, S, Rahman, A, Rahman, MHU, Rahmani, AM, Rai, RK, Ranabhat, CL, Rao, SJ, Rastogi, P, Rathi, P, Rawaf, DL, Rawaf, S, Rawassizadeh, R, Rawat, R, Regassa, LD, Rego, MAS, Reiner, RC, Reshmi, B, Rezapour, A, Ribeiro, AI, Rickard, J, Roever, L, Rumisha, SF, Rwegerera, GM, Sagar, R, Sajadi, SM, Salem, MR, Samy, AM, Santric-Milicevic, MM, Saraswathy, SYI, Sarker, AR, Sartorius, B, Sathian, B, Saxena, D, Sbarra, AN, Sengupta, D, Senthilkumaran, S, Sha, F, Shafaat, O, Shaheen, AA, Shaikh, MA, Shalash, AS, Shannawaz, M, Sheikh, A, Shetty, BSK, Shetty, RS, Shibuya, K, Shiferaw, WS, Shin, JI, Silva, DAS, Singh, NP, Singh, P, Singh, S, Sintayehu, Y, Skryabin, VY, Skryabina, AA, Soheili, A, Soltani, S, Sorrie, MB, Spurlock, EE, Steuben, KM, Sudaryanto, A, Sufiyan, MB, Swartz, SJ, Tadesse, EG, Tamiru, AT, Tapak, L, Tareque, MI, Tarigan, IU, Tesema, GA, Tesfay, FH, Teshome, A, Tessema, ZT, Thankappan, KR, Thapar, R, Thomas, N, Topor-Madry, R, Tovani-Palone, MR, Traini, E, Tran, BX, Truong, PN, Tsegaye, BTBT, Ullah, I, Umeokonkwo, CD, Unnikrishnan, B, Upadhyay, E, Uzochukwu, BSC, VanderHeide, JD, Violante, FS, Vo, B, Wado, YD, Waheed, Y, Wamai, RG, Wang, F, Wang, Y, Wang, Y-P, Wickramasinghe, ND, Wiens, KE, Wiysonge, CS, Woyczynski, L, Wu, A-M, Wu, C, Yamada, T, Yaya, S, Yeshaneh, A, Yeshaw, Y, Yeshitila, YG, Yilma, MT, Yip, P, Yonemoto, N, Yosef, T, Younis, MZ, Yousuf, AY, Yu, C, Yu, Y, Yuce, D, Zafar, S, Zaidi, SS, Zaki, L, Zakzuk, J, Zamanian, M, Zar, HJ, Zastrozhin, MS, Zastrozhina, A, Zelellw, DA, Zhang, Y, Zhang, Z-J, Zhao, X-JG, Zodpey, S, Zuniga, YMH, Local Burden of Disease Exclusive Breastfeeding Collaborators, Bhattacharjee, Natalia V, Schaeffer, Lauren E, Hay, Simon I, Duko, Bereket, Yeshaw, Yigizie, Local Burden of Disease Exclusive Breastfeeding Collaborators, Bhattacharjee N.V., Schaeffer L.E., Hay S.I., Lu D., Schipp M.F., Lazzar-Atwood A., Donkers K.M., Abady G.G., Abd-Allah F., Abdelalim A., Abebo Z.H., Abejie A.N., Abosetugn A.E., Abreu L.G., Abrigo M.R.M., Abu-Gharbieh E., Abushouk A.I., Adamu A.L., Adedeji I.A., Adegbosin A.E., Adekanmbi V., Adetokunboh O.O., Agudelo-Botero M., Aji B., Akinyemi O.O., Alamneh A.A., Alanezi F.M., Alanzi T.M., Albright J., Alcalde-Rabanal J.E., Alemu B.W., Alhassan R.K., Ali B.A., Ali S., Alinia C., Alipour V., Amit A.M.L., Amugsi D.A., Anbesu E.W., Ancuceanu R., Anjomshoa M., Ansari F., Antonio C.A.T., Anvari D., Arabloo J., Arora A., Artanti K.D., Asemahagn M.A., Asmare W.N., Atout M.M.W., Ausloos M., Awoke N., Quintanilla B.P.A., Ayanore M.A., Aynalem Y.A., Ayza M.A., Azene Z.N., Darshan B.B., Badiye A.D., Baig A.A., Bakkannavar S.M., Banach M., Banik P.C., Barnighausen T.W., Basaleem H., Bayati M., Baye B.A., Bedi N., Belay S.A., Bhagavathula A.S., Bhandari D., Bhardwaj N., Bhardwaj P., Bhutta Z.A., Bijani A., Birhan T.A., Birihane B.M., Bitew Z.W., Bohlouli S., Bohluli M., Bojia H.A., Boloor A., Brady O.J., Bragazzi N.L., Brunoni A.R., Budhathoki S.S., Nagaraja S.B., Butt Z.A., Cardenas R., Castaldelli-Maia J.M., Castro F., Cernigliaro A., Charan J., Chatterjee P., Chatterjee S., Chattu V.K., Chaturvedi S., Chowdhury M.A.K., Chu D.-T., Collison M.L., Cook A.J., Cork M.A., Couto R.A.S., Dagnew B., Dai H., Dandona L., Dandona R., Daneshpajouhnejad P., Darwesh A.M., Darwish A.H., Daryani A., Das J.K., Gupta R.D., Davila-Cervantes C.A., Davis A.C., Weaver N.D., Denova-Gutierrez E., Deribe K., Desalew A., Deshpande A., Dessie A., Deuba K., Dharmaratne S.D., Dhimal M., Dhungana G.P., Diaz D., Didarloo A., Dipeolu I.O., Doan L.P., Duko B., Duraes A.R., Dwyer-Lindgren L., Earl L., Zaki M.E.S., Tantawi M.E., Elema T.B., Elhabashy H.R., El-Jaafary S.I., Faris P.S., Faro A., Farzadfar F., Feigin V.L., Feleke B.E., Ferede T.Y., Fischer F., Foigt N.A., Folayan M.O., Franklin R.C., Gad M.M., Gaidhane S., Gardner W.M., Geberemariyam B.S., Gebregiorgis B.G., Gebremedhin K.B., Gebremichael B., Ghaffarpasand F., Gilani S.A., Ginindza T.G., Glagn M., Golechha M., Gonfa K.B., Goulart B.N.G., Gudi N., Guido D., Guled R.A., Guo Y., Hamidi S., Handiso D.W., Hasaballah A.I., Hassan A., Hayat K., Hegazy M.I., Heidari B., Henry N.J., Herteliu C., de Hidru H.D., Ho H.C., Hoang C.L., Holla R., Hon J., Hosseini M., Hosseinzadeh M., Househ M., Hsairi M., Hu G., Huda T.M., Hwang B.-F., Ibitoye S.E., Ilesanmi O.S., Ilic I.M., Ilic M.D., Inbaraj L.R., Iqbal U., Irvani S.S.N., Islam M.M., Iwu C.C.D., Iwu C.J., Jain A., Janodia M.D., Javaheri T., John-Akinola Y.O., Johnson K.B., Joukar F., Jozwiak J.J., Kabir A., Kalankesh L.R., Kalhor R., Kamath A., Kamyari N., Kanchan O.T., Kapoor N., Matin B.K., Karimi S.E., Kasaye H.K., Kassahun G., Kassebaum N.J., Kayode G.A., Karyani A.K., Keiyoro P.N., Kelkay B., Khalid N., Khan M.N., Khatab K., Khater A.M., Khater M.M., Khatib M.N., Kim Y.J., Kimokoti R.W., Kinyoki D.K., Kisa A., Kisa S., Kosen S., Krishan K., Kulkarni V., Kumar G.A., Kumar M., Kumar N., Kumar P., Kurmi O.P., Kusuma D., Vecchia C.L., Lad S.D., Lami F.H., Landires I., Lansingh V.C., Lasrado S., Lee P.H., LeGrand K.E., Letourneau I.D., Lewycka S., Li B., Li M.-C., Li S., Liu X., Lodha R., Lopez J.C.F., Louie C., Machado D.B., Maled V., Maleki S., Malta D.C., Mamun A.A., Manafi N., Mansournia M.A., Mapoma C.C., Marczak L.B., Martins-Melo F.R., Mehndiratta M.M., Mejia-Rodriguez F., Mekonnen T.C., Mendoza W., Menezes R.G., Mengesha E.W., Mersha A.M., Miller T.R., Mini G.K., Mirrakhimov E.M., Misra S., Moghadaszadeh M., Mohammad D.K., Mohammadian-Hafshejani A., Mohammed J.A., Mohammed S., Mokdad A.H., Montero-Zamora P.A., Moradi M., Moradzadeh R., Moraga P., Mosser J.F., Mousavi S.M., Khaneghah A.M., Munro S.B., Muriithi M.K., Mustafa G., Muthupandian S., Nagarajan A.J., Naik G., Naimzada M.D., Nangia V., Nascimento B.R., Nayak V.C., Ndejjo R., Ndwandwe D.E., Negoi I., Nguefack-Tsague G., Ngunjiri J.W., Nguyen C.T., Nguyen D.N., Nguyen H.L.T., Nigussie S.N., Nigussie T.T.N., Nikbakhsh R., Nnaji C.A., Nunez-Samudio V., Oancea B., Oghenetega O.B., Olagunju A.T., Olusanya B.O., Olusanya J.O., Omer M.O., Onwujekwe O.E., Ortega-Altamirano D.V., Osgood-Zimmerman A.E., Otstavnov N., Otstavnov S.S., Owolabi M.O., Mahesh P.A., Padubidri J.R., Pana A., Pandey A., Pandi-Perumal S.R., Pangaribuan H.U., Parsekar S.S., Pasupula D.K., Patel U.K., Pathak A., Pathak M., Pattanshetty S.M., Patton G.C., Paulos K., Pepito V.C.F., Pickering B.V., Pinheiro M., Piwoz E.G., Pokhrel K.N., Pourjafar H., Prada S.I., Pribadi D.R.A., Syed Z.Q., Rabiee M., Rabiee N., Rahim F., Rahimzadeh S., Rahman A., Rahman M.H.U., Rahmani A.M., Rai R.K., Ranabhat C.L., Rao S.J., Rastogi P., Rathi P., Rawaf D.L., Rawaf S., Rawassizadeh R., Rawat R., Regassa L.D., Rego M.A.S., Reiner R.C., Reshmi B., Rezapour A., Ribeiro A.I., Rickard J., Roever L., Rumisha S.F., Rwegerera G.M., Sagar R., Sajadi S.M., Salem M.R., Samy A.M., Santric-Milicevic M.M., Saraswathy S.Y.I., Sarker A.R., Sartorius B., Sathian B., Saxena D., Sbarra A.N., Sengupta D., Senthilkumaran S., Sha F., Shafaat O., Shaheen A.A., Shaikh M.A., Shalash A.S., Shannawaz M., Sheikh A., Shetty B.S.K., Shetty R.S., Shibuya K., Shiferaw W.S., Shin J.I., Silva D.A.S., Singh N.P., Singh P., Singh S., Sintayehu Y., Skryabin V.Y., Skryabina A.A., Soheili A., Soltani S., Sorrie M.B., Spurlock E.E., Steuben K.M., Sudaryanto A., Sufiyan M.B., Swartz S.J., Tadesse E.G., Tamiru A.T., Tapak L., Tareque M.I., Tarigan I.U., Tesema G.A., Tesfay F.H., Teshome A., Tessema Z.T., Thankappan K.R., Thapar R., Thomas N., Topor-Madry R., Tovani-Palone M.R., Traini E., Tran B.X., Truong P.N., Tsegaye B.T.B.T., Ullah I., Umeokonkwo C.D., Unnikrishnan B., Upadhyay E., Uzochukwu B.S.C., VanderHeide J.D., Violante F.S., Vo B., Wado Y.D., Waheed Y., Wamai R.G., Wang F., Wang Y., Wang Y.-P., Wickramasinghe N.D., Wiens K.E., Wiysonge C.S., Woyczynski L., Wu A.-M., Wu C., Yamada T., Yaya S., Yeshaneh A., Yeshaw Y., Yeshitila Y.G., Yilma M.T., Yip P., Yonemoto N., Yosef T., Younis M.Z., Yousuf A.Y., Yu C., Yu Y., Yuce D., Zafar S., Zaidi S.S., Zaki L., Zakzuk J., Zamanian M., Zar H.J., Zastrozhin M.S., Zastrozhina A., Zelellw D.A., Zhang Y., Zhang Z.-J., Zhao X.-J.G., Zodpey S., Zuniga Y.M.H., Collaborators, Local Burden of Disease Exclusive Breastfeeding, and Instituto de Saúde Pública da Universidade do Porto

Subjects
RJ101, Psychological intervention, Breastfeeding, Social Sciences, geography, Behavioral Neuroscience, 0302 clinical medicine, RA0421, Prevalence, Psychology, policy making, 030212 general & internal medicine, Policy Making, humans, media_common, CHILD GROWTH FAILURE, Developing world, 0303 health sciences, education.field_of_study, Psychology, Biological, Geography, Psychology, Experimental, Health Status Disparitie, Multidisciplinary Sciences, Breast Feeding, breast feeding, Scale (social sciences), Science & Technology - Other Topics, Life Sciences & Biomedicine, Human, AFRICA, Social Psychology, Inequality, spatial analysis, media_common.quotation_subject, public policy, Population, prevalence, Public policy, Developing country, Experimental and Cognitive Psychology, Public Policy, Local Burden of Disease Exclusive Breastfeeding Collaborators, Article, Developing Countrie, 03 medical and health sciences, Environmental health, Humans, Nutrition disorders, education, Developing Countries, 030304 developmental biology, Spatial Analysis, Science & Technology, Neurosciences, Health Status Disparities, developing countries, health status disparities, Risk factors, Neurosciences & Neurology, Breast feeding
Abstract

Exclusive breastfeeding (EBF)—giving infants only breast-milk for the first 6 months of life—is a component of optimal breastfeeding practices effective in preventing child morbidity and mortality. EBF practices are known to vary by population and comparable subnational estimates of prevalence and progress across low- and middle-income countries (LMICs) are required for planning policy and interventions. Here we present a geospatial analysis of EBF prevalence estimates from 2000 to 2018 across 94 LMICs mapped to policy-relevant administrative units (for example, districts), quantify subnational inequalities and their changes over time, and estimate probabilities of meeting the World Health Organization’s Global Nutrition Target (WHO GNT) of ≥70% EBF prevalence by 2030. While six LMICs are projected to meet the WHO GNT of ≥70% EBF prevalence at a national scale, only three are predicted to meet the target in all their district-level units by 2030., Bhattacharjee and Schaeffer et al. map exclusive breastfeeding (EBF) in 94 low- and middle-income countries (LMICs), finding increased EBF practice and reduced subnational variation across the majority of LMICs from 2000 to 2018. However, only six LMICs will meet WHO’s target of ≥70% EBF by 2030 nationally, and only three will achieve this in all districts.

Published
2021

5. Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning

Author

Fereshteh Ansari, Richard C. Franklin, Naznin Hossain, Rodrigo Sarmiento-Suárez, Mahdi Bohluli, Irena Ilic, Anwar Faraj, Soosanna Kumary Chattu, Sanni Yaya, Hagos Degefa Hidru, Morteza Shamsizadeh, Ehsan Sadeghi, Bach Xuan Tran, Leila Zaki, Mohammad Miri, Maha El Tantawi, Maciej Banach, Hasan Yusefzadeh, Kira A Barbre, Chigozie Jesse Uneke, Mehdi Naderi, Behzad Karami Matin, Yunquan Zhang, Vahid Yazdi-Feyzabadi, Emma Elizabeth Spurlock, Zahid A Butt, Nuruzzaman Khan, Robert L. Thompson, Mehdi Hosseinzadeh, Rovshan Khalilov, Usman Iqbal, K M Shivakumar, Leili Tapak, Chris A Schmidt, Priya Rathi, Shanshan Li, Bhaskaran Unnikrishnan, Chuanhua Yu, Elizabeth A. Cromwell, Davood Anvari, Hoa Thi Do, Abdullah Al Mamun, Obinna Onwujekwe, Serge Resnikoff, Majid Fasihi Harandi, Joshua C. P. Osborne, Farahnaz Joukar, Aso Mohammad Darwesh, Rohollah Kalhor, Turki Alanzi, Katie M Donkers, Amir Kasaeian, Eirini Skiadaresi, Aleksandra Barac, Simon I. Hay, Paul S. F. Yip, Tomislav Mestrovic, Zhi-Jiang Zhang, Katherine Gass, Cuong Tat Nguyen, Gurudatta Naik, Joshua Longbottom, Somayeh Bohlouli, Aziz Rezapour, Huong Lan Thi Nguyen, Khaled Khatab, Mohammed Ibrahim Mohialdeen Gubari, Ahmed Omar Bali, Temesgen Yihunie Akalu, Paul H. Lee, Vahid Alipour, Kebede Deribe, Megan F. Schipp, Ziyad Al-Aly, Biagio Simonetti, Masoud Moradi, Jalal Arabloo, Reza Rawassizadeh, Saif Ullah, Seth Christopher Yaw Appiah, Demelash Abewa Elemineh, Abedin Saghafipour, Fakher Rahim, Tinuke O Olagunju, Kimberly B. Johnson, Souranshu Chatterjee, Salvatore Rubino, Nataliya Foigt, Olayinka Stephen Ilesanmi, Taras Kavetskyy, Carlo La Vecchia, Eduarda Fernandes, Mohsen Mazidi, Claudiu Herteliu, Sojib Bin Zaman, Aziz Sheikh, Yong Yu, David Laith Rawaf, Hassan Magdy Abd El Razek, Natalie V S Vinkeles Melchers, Samath D Dharmaratne, Enrico Rubagotti, Fahad Alanezi, Masood Ali Shaikh, Masoud Foroutan, B. Suresh Kumar Shetty, Milena Ilic, Melese Abate Reta, Dian Kusuma, Ali Manafi, Krittika Bhattacharyya, Giovanni Damiani, Kanaan Hamagharib Abdullah, Desalegn Tadese Mengistu, Van C. Lansingh, Till Bärnighausen, Benjamin F. Arnold, Natalie Maria Cormier, Zulfiqar A Bhutta, Ahmad Daryani, Ali Bijani, Jae Il Shin, Samer Hamidi, Jasvinder A. Singh, Mohsen Bayati, Tomohide Yamada, Zubair Kabir, Muhammed Magdy Abd El Razek, Jonathan F. Mosser, Gbenga A. Kayode, Martin Amogre Ayanore, Shahin Soltani, Arvin Haj-Mirzaian, Mohammad Ali Mansournia, Salah Eddin Karimi, Alan J Thomson, Daniel Diaz, Ahamarshan Jayaraman Nagarajan, Adrian Pana, Salman Rawaf, Oliver J. Brady, Birhanu Geta Meharie, Yousef Fatahi, Sadia Bibi, Bogdan Oancea, Masoud Moghadaszadeh, Kelemu Tilahun Kibret, Valery L. Feigin, Saad M.A. Dahlawi, Ted R. Miller, Nicola Luigi Bragazzi, Atif Amin Baig, Maryam Zamanian, Kate E. LeGrand, Salahuddin Mohammed, Yuming Guo, Irfan Ullah, Hebat Allah Salah A. Yousof, Mowafa Househ, Ionut Negoi, Naohiro Yonemoto, Reza Mohammadpourhodki, Hadi Pourjafar, Navid Manafi, Neda Kianipour, Abraham Getachew Kelbore, Victor Adekanmbi, Seid Tiku Mereta, Olalekan A. Uthman, Arash Ziapour, Olatunji O. Adetokunboh, Trang Huyen Nguyen, Seyed Sina Naghibi Irvani, Francesco Saverio Violante, Monika Sawhney, Paula Moraga, Rahmatollah Moradzadeh, Mu'awiyyah Babale Sufiyan, Mohammad Hifz Ur Rahman, María-Gloria Basáñez, Vijay Kumar Chattu, Mustafa Geleto Ansha, Mona M. Khater, Andrew T Olagunju, Ejaz Ahmad Khan, Davide Guido, Kiomars Sharafi, S. Mohammad Sajadi, Francisco Rogerlândio Martins-Melo, Tarig B. Higazi, Afshin Maleki, Abdollah Mohammadian-Hafshejani, Soewarta Kosen, Amin Soheili, Félix Carvalho, Yun Jin Kim, Catalina Liliana Andrei, Ali Kazemi Karyani, Ehsan Ahmadpour, Thomas R. Unnasch, Mohsen Afarideh, Takahiro Tabuchi, Shreya Shirude, Marcel Ausloos, Maysaa El Sayed Zaki, Haileab Fekadu Wolde, Amira Shaheen, Shafiu Mohammed, Rajan Nikbakhsh, Tewodros Eshete Wonde, Endalkachew Worku Mengesha, Jacek Jerzy Jozwiak, Muktar Beshir Ahmed, Eugenio Traini, Leila R Kalankesh, Kris J. Krohn, Colm McAlinden, Walter Mendoza, Maryam Keramati, Ravi Prakash Jha, David M. Pigott, Elex Hill, Abdallah M. Samy, Farah Daoud, Wanji, Samuel, Public Health, Bill & Melinda Gates Foundation, Medical Research Council (Reino Unido), Department for International Development (Reino Unido), Unión Europea, Cromwell E.A., Osborne J.C.P., Unnasch T.R., Basanez M., Gass K.M., Barbre K.A., Hill E., Johnson K.B., Donkers K.M., Shirude S., Schmidt C.A., Adekanmbi V., Adetokunboh O.O., Afarideh M., Ahmadpour E., Beshir Ahmed M., Yihunie Akalu T., Al-Aly Z., Alanezi F.M., Alanzi T.M., Alipour V., Andrei C.L., Ansari F., Ansha M.G., Anvari D., Yaw Appiah S.C., Arabloo J., Arnold B.F., Ausloos M., Ayanore M.A., Amin Baig A., Banach M., Barac A., Barnighausen T.W., Bayati M., Bhattacharyya K., Bhutta Z.A., Bibi S., Bijani A., Bohlouli S., Bohluli M., Brady O.J., Bragazzi N.L., Butt Z.A., Carvalho F., Chatterjee S., Chattu V.K., Chattu S.K., Cormier N.M., Dahlawi S.M.A., Damiani G., Daoud F., Darwesh A.M., Daryani A., Deribe K., Dharmaratne S.D., Diaz D., Do H.T., El Sayed Zak M., El Tantawi M., Elemineh D.A., Faraj A., Harandi M.F., Fatahi Y., Feigin V.L., Fernandes E., Foigt N.A., Foroutan M., Franklin R.C., Mohialdeen Gubari M.I., Guido D., Guo Y., Haj-Mirzaian A., Abdullah K.H., Hamidi S., Herteliu C., De Hidru H.D., Higazi T.B., Hossain N., Hosseinzadeh M., Househ M., Ilesanmi O.S., Ilic M.D., Ilic I.M., Iqbal U., Naghibi Irvani S.S., Jha R.P., Joukar F., Jozwiak J.J., Kabir Z., Kalankesh L.R., Kalhor R., Matin B.K., Karimi S.E., Kasaeian A., Kavetskyy T., Kayode G.A., Karyani A.K., Kelbore A.G., Keramati M., Khalilov R., Khan E.A., Nuruzzaman Khan M.N., Khatab K., Khater M.M., Kianipour N., Kibret K.T., Kim Y.J., Kosen S., Krohn K.J., Kusuma D., Vecchia C.L., Lansingh Van C., Lee P.H., Legrand K.E., Li S., Longbottom J., Abd El Razek H.M., Abd El Razek M.M., Maleki A., Mamun A.A., Manafi A., Manafi N., Mansournia M.A., Martins-Melo F.R., Mazidi M., McAlinden C., Meharie B.G., Mendoza W., Mengesha E.W., Mengistu D.T., Mereta S.T., Mestrovic T., Miller T.R., Miri M., Moghadaszadeh M., Hafshejani A.M., Mohammadpourhodki R., Mohammed S., Moradi M., Moradzadeh R., Moraga P., Mosser J.F., Naderi M., Nagarajan A.J., Naik G., Negoi I., Nguyen C.T., Nguyen H.L.T., Nguyen T.H., Nikbakhsh R., Oancea B., Olagunju T.O., Olagunju A.T., Bali A.O., Onwujekwe O.E., Pana A., Pourjafar H., Rahim F., Ur Rahman M.H., Rathi P., Rawaf S., Rawaf D.L., Rawassizadeh R., Resnikoff S., Reta M.A., Rezapour A., Rubagotti E., Rubino S., Sadeghi E., Saghafipour A., Sajadi S.M., Samy A.M., Sarmiento-Suarez R., Sawhney M., Schipp M.F., Shaheen A.A., Shaikh M.A., Shamsizadeh M., Sharafi K., Sheikh A., Kumar Shetty B.S., Shin J.I., Shivakumar K.M., Simonetti B., Singh J.A., Skiadaresi E., Soheili A., Soltani S., Spurlock E.E., Sufiyan M.B., Tabuchi T., Tapak L., Thompson R.L., Thomson A.J., Traini E., Tran B.X., Ullah I., Ullah S., Uneke C.J., Unnikrishnan B., Uthman O.A., Melchers N.V.S.V., Violante F.S., Wolde H.F., Wonde T.E., Yamada T., Yaya S., Yazdi Feyzabadi V., Yip P., Yonemoto N., Yousof H.-A.S.A., Yu C., Yu Y., Yusefzadeh H., Zaki L., Zaman S.B., Zamanian M., Zhang Z.-J., Zhang Y., Ziapour A., Hay S.I., Pigott D.M., and Cuidado de la Salud y Desarrollo Sostenible

Subjects
Oncocercosis, Decision Analysis, RC955-962, Onchocerciasis, law.invention, Geographical Locations, Medical Conditions, 0302 clinical medicine, law, Arctic medicine. Tropical medicine, Medicine and Health Sciences, 030212 general & internal medicine, Onchocerca, 11 Medical and Health Sciences, Data Management, biology, Pharmaceutics, wc_695, Enfermedades Parasitarias, Onchocerciasi, 3. Good health, Infectious Diseases, Geography, Transmission (mechanics), Helminth Infections, Engineering and Technology, Mass Drug Administration, Public aspects of medicine, RA1-1270, Management Engineering, Cartography, Human, Research Article, Neglected Tropical Diseases, Computer and Information Sciences, Drug Administration, 030231 tropical medicine, Decision tree, wa_395, Dermatology, wc_765, Environment, wc_885, Research and Analysis Methods, Skin Diseases, 03 medical and health sciences, Drug Therapy, SDG 3 - Good Health and Well-being, Diagnostic Medicine, Tropical Medicine, Parasitic Diseases, medicine, Humans, Disease Eradication, Spatial analysis, Ivermectin, Data collection, Receiver operating characteristic, Data Visualization, Decision Trees, Public Health, Environmental and Occupational Health, 06 Biological Sciences, Elimination planning, Africa, Implementation units, Public health, Tropical Diseases, medicine.disease, biology.organism_classification, Health Care, ROC Curve, People and Places, Health Statistics, Morbidity, Scale (map), Forecasting
Abstract

Recent evidence suggests that, in some foci, elimination of onchocerciasis from Africa may be feasible with mass drug administration (MDA) of ivermectin. To achieve continental elimination of transmission, mapping surveys will need to be conducted across all implementation units (IUs) for which endemicity status is currently unknown. Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. In order to classify IUs that include locations that are environmentally suitable, we used receiver operating characteristic (ROC) analysis to identify an optimal threshold for suitability concordant with locations where onchocerciasis has been previously detected. This threshold value was then used to classify IUs (more suitable or less suitable) based on the location within the IU with the largest mean prediction. Mean estimates of environmental suitability suggest large areas across West and Central Africa, as well as focal areas of East Africa, are suitable for onchocerciasis transmission, consistent with the presence of current control and elimination of transmission efforts. The ROC analysis identified a mean environmental suitability index of 0·71 as a threshold to classify based on the location with the largest mean prediction within the IU. Of the IUs considered for mapping surveys, 50·2% exceed this threshold for suitability in at least one 5 × 5-km location. The formidable scale of data collection required to map onchocerciasis endemicity across the African continent presents an opportunity to use spatial data to identify areas likely to be suitable for onchocerciasis transmission. National onchocerciasis elimination programmes may wish to consider prioritising these IUs for mapping surveys as human resources, laboratory capacity, and programmatic schedules may constrain survey implementation, and possibly delaying MDA initiation in areas that would ultimately qualify., Author summary As of 2018, it was unknown if onchocerciasis transmission occurred among approximately 2 400 implementation units (IUs; typically, second administrative-level units, such as districts) considered potentially endemic. These IUs have either never been surveyed for onchocerciasis or historical data are not sufficient to define contemporary endemicity status. Given the large number of IUs for which baseline data collection is likely required to achieve continental elimination, there is a need to prioritise areas for surveys to ensure that those suitable for endemic transmission, and therefore potentially eligible for mass drug administration, are able to initiate interventions as soon as possible. We used boosted regression trees to predict environmental suitability for onchocerciasis, with corresponding measures of uncertainty. We summarized the fine scale spatial predictions at the IU level by using receiver operating characteristic (ROC) curve analysis to identify a threshold that maximized agreement with the occurrence locations to identify IUs that may warrant prioritisation for mapping surveys. This analysis suggests that approximately half of the IUs considered for surveys could be classified as environmentally suitable for onchocerciasis. In order to develop an elimination strategy, many national onchocerciasis elimination programmes (NOEPs) need a mechanism to synthesise historical data to define priority areas for surveys.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results