Search

Your search keyword '"de Groot, C.P."' showing total 7 results
Start Over Author "de Groot, C.P."
7 results on '"de Groot, C.P."'

3. A method for measuring heteronuclear (1H-13C) distances in high speed MAS NMR

Author

van Rossum, B.-J., de Groot, C.P., Ladizhanasky, V., and de Groot, H.J.M.

Subjects
Chemical bonds -- Measurement, Chemistry, Physical and theoretical -- Research, Layer structure (Solids) -- Research, Nuclear magnetic resonance spectroscopy -- Usage, Chemistry
Abstract

A method for determining heteronuclear distances in uniformly 13C enriched compounds, using magic angle spinning NMR structure determination, is presented.

Published
2000

4. SUN-LB305: The Effect of Nutritional Intervention in Older Adults on Handgrip Strength And Mortality: Results from 9 Pooled RCTs

Author

Van Zwienen-Pot, J.I., primary, Reinders, I., additional, de Groot, C.P., additional, Beck, A.M., additional, Feldblum, I., additional, Jobse, I., additional, Neelemaat, F., additional, de van der Schueren, M.A., additional, Shahar, D.R., additional, Smeets, E.T., additional, Tieland, M., additional, Wijnhoven, H.A., additional, Volkert, D., additional, and Visser, M., additional

Published
2017
Full Text
View/download PDF

6. Genetic factors as predictors of weight gain in young adult Dutch men and women

Author

van Rossum, C.T., van Rossum, C.T., Hoebee, B., Seidell, J.C., Bouchard, C., van Baak, M.A., de Groot, C.P., Chagnon, M., de Graaf, C., van Rossum, C.T., van Rossum, C.T., Hoebee, B., Seidell, J.C., Bouchard, C., van Baak, M.A., de Groot, C.P., Chagnon, M., and de Graaf, C.

Abstract

Department of Chronic Diseases Epidemiology, National Institute of Public Health and the Environment, Bilthoven, The Netherlands. caroline.van.rossum@rivm.nl OBJECTIVE: To investigate the association between DNA polymorphisms in several candidate genes for obesity and weight gain. Polymorphisms in these genes may contribute to weight gain through effects on energy intake, energy expenditure or adipogenesis. DESIGN AND METHODS: From two large cohorts in The Netherlands (total 17,500 adult men and women), we compared 286 subjects aged 20-40 y who gained an average of 12.8 kg (range 5.5-47 kg) during a mean follow-up of 6.8 y with 296 subjects who remained relatively constant over the same period with respect to occurrence of several polymorphisms in candidate genes of obesity and some lifestyle factors. Subjects who were dieting, were high alcohol consumers, were pregnant, changed their smoking status recently, or those who suffered from serious illnesses were excluded. Polymorphisms were determined in the LEPR-gene (LEPR Lys109Arg, LEPR Gln223Arg, LEPR Lys656Asn), in the UCP1 gene (A-G mutation at position-3826 5' region), in the UCP2 gene (Ala55Val, 45 bp Ins/Del), in the PPARG2 gene (Pro12Ala) and in the ADRB2 gene (Gly16Arg and Gln27Glu). RESULTS: With the exception of the Gly16Arg polymorphism in the ADRB2 gene in men (P = 0.04) and women (P = 0.05), and the Lys109Arg polymorphism in the LEPR gene in women, no statistically significant differences in the genotype and allele frequencies were observed between weight gainers and non-weight gainers. Weight gainers differed in some aspects of dietary habits and physical activity patterns: weight gainers consumed relatively more savory snacks and were less active during leisure time compared with non-weight gainers. CONCLUSION: Only variations in the ADRB2 gene and LEPR gene, may contribute to susceptibility to weight gain. None of the other studied genetic markers were clearly associated with weight gain. Fur

Published
2002

7. Combating inflammaging through a Mediterranean whole diet approach: The NU-AGE project's conceptual framework and design

Author

Aurelia Santoro, Elisa Pini, Maria Scurti, Giustina Palmas, Agnes Berendsen, Anna Brzozowska, Barbara Pietruszka, Anna Szczecinska, Noël Cano, Nathalie Meunier, C.P.G.M. de Groot, Edith Feskens, Susan Fairweather-Tait, Stefano Salvioli, Miriam Capri, Patrizia Brigidi, Claudio Franceschi, Cristina Fabbri, Claudia Bertarelli, Massimo Izzi, Mario Mazzocchi, Jean Michel Chardigny, Beatrice Morio, Daniele Rossi, Maurizio Notarfonso, Paul W. O’Toole, Kevin Cashman, Simon R. Carding, Claudio Nicoletti, Dirk Jacobs, Maria Xipsiti, Laura Fernandez, Josephine Wills, Xavier Irz, Natalia Kuosmanen, Efstathios S. Gonos, Konstantinos Voutetakis, Michael Salmon, Olivier Toussaint, Bruce W. Traill, Giuseppe Nocella, Barbara Caracciolo, Weili Xu, null Mikko Ikonen, Tuula Tuure, Robert Brummer, Fawzi Kadi, Sylvie Breton, Marie Triomphe, Guido Magario, Filippo Villani, Annibale Pancrazio, Brigitte Teufner, Josef Stocker, Francisco Javier Echevarría, Jose Ramón Iglesias, František Smrž, Lucie Krejcirova, Efthimia Koytsomitropoulou, Konstantinos Georgakidis, Rezan Yornuk, Cihan Ucar, Ben Van Ommen, Jildau Bouwman, Sebastiano Collino, Clara Jankovics, Adrienn Losó, Willem de Vos, Susana Fuentes, Eric Commelin, Department of Experimental Diagnostic and Specialty Medicine, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Department of Human Nutrition, Wageningen University and Research [Wageningen] (WUR), Warsaw University of Life Sciences (SGGW), Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université, Unité d'exploration en Nutrition, CHU Clermont-Ferrand, Norwich Medical School, University of East Anglia [Norwich] (UEA), Department of Pharmacy and Biotechnology, NU-AGE Consortium, Partenaires INRAE, Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), European Union's Seventh Framework Program, European Project: 266486,EC:FP7:KBBE,FP7-KBBE-2010-4,NU-AGE(2011), Santoro A., Pini E., Scurti M., Palmas G., Berendsen A., Brzozowska A., Pietruszka B., Szczecinska A., Cano N., Meunier N., de Groot C.P., Feskens E., Fairweather-Tait S., Salvioli S., Capri M., Brigidi P., Franceschi C., The NU-AGE Consortium [, Cristina Fabbri, Claudia Bertarelli, Massimo Izzi], Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université-Institut National de la Recherche Agronomique (INRA), and Centre des Sciences du Goût et de l'Alimentation (CSGA)

Subjects
Gerontology, Research design, Male, Aging, Nutrition and Disease, Mediterranean diet, Laboratorium voor Fysische chemie en Kolloïdkunde, muscle, Health Status, Biomedical Innovation, Diet, Mediterranean, Feeding behavior, Life, Microbiologie, Voeding en Ziekte, [SDV.IDA]Life Sciences [q-bio]/Food engineering, cellular senescence, Food Industry, Multicenter Studies as Topic, older-adults, Physical Chemistry and Colloid Science, Human Nutrition & Health, Randomized Controlled Trials as Topic, immunosenescence, 2. Zero hunger, Systems Biology, Humane Voeding & Gezondheid, 3. Good health, Variety (cybernetics), Mitochondria, Europe, Intestines, Multinational corporation, Research Design, Food, Fortified, Female, Healthy Living, phenotype, Cellular senescence, frailty, Gut microbiota, system, Biology, Microbiology, longevity, elderly-tailored food, Humans, [SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering, style diet, Elderly-tailored foods, Beneficial effects, cd8(+) t-cells, VLAG, Aged, Global Nutrition, Inflammation, Wereldvoeding, Feeding Behavior, Inflammaging, Diet, Ageing, MSB - Microbiology and Systems Biology, Conceptual framework, Food, ELSS - Earth, Life and Social Sciences, Developmental Biology
Abstract

International audience; The development of a chronic, low grade, inflammatory status named "inflammaging" is a major characteristic of ageing, which plays a critical role in the pathogenesis of age-related diseases. Inflammaging is both local and systemic, and a variety of organs and systems contribute inflammatory stimuli that accumulate lifelong. The NU-AGE rationale is that a one year Mediterranean whole diet (considered by UNESCO a heritage of humanity), newly designed to meet the nutritional needs of the elderly, will reduce inflammaging in fully characterized subjects aged 65-79 years of age, and will have systemic beneficial effects on health status (physical and cognitive). Before and after the dietary intervention a comprehensive set of analyses, including omics (transcriptomics, epigenetics, metabolomics and metagenomics) will be performed to identify the underpinning molecular mechanisms. NU-AGE will set up a comprehensive database as a tool for a systems biology approach to inflammaging and nutrition. NU-AGE is highly interdisciplinary, includes leading research centres in Europe on nutrition and ageing, and is complemented by EU multinational food industries and SMEs, interested in the production of functional and enriched/advanced traditional food tailored for the elderly market, and European Federations targeting policy makers and major stakeholders, from consumers to EU Food & Drink Industries.

Published
2014

Catalog

Books, media, physical & digital resources
See catalog results