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2. Depression, cardiometabolic disease, and their co-occurrence after childhood maltreatment: an individual participant data meta-analysis including over 200,000 participants

Author

Souama, Camille, Lamers, Femke, Milaneschi, Yuri, Vinkers, Christiaan H., Defina, Serena, Garvert, Linda, Stein, Frederike, Woofenden, Tom, Brosch, Katharina, Dannlowski, Udo, Galenkamp, Henrike, de Graaf, Ron, Jaddoe, Vincent W. V., Lok, Anja, van Rijn, Bas B., Völzke, Henry, Cecil, Charlotte A. M., Felix, Janine F., Grabe, Hans J., Kircher, Tilo, Lekadir, Karim, Have, Margreet ten, Walton, Esther, and Penninx, Brenda W. J. H.

Published
2023
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10. Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis

Author

Kocevska, Desana, Lysen, Thom S., Dotinga, Aafje, Koopman-Verhoeff, M. Elisabeth, Luijk, Maartje P. C. M., Antypa, Niki, Biermasz, Nienke R., Blokstra, Anneke, Brug, Johannes, Burk, Wiliam J., Comijs, Hannie C., Corpeleijn, Eva, Dashti, Hassan S., de Bruin, Eduard J., de Graaf, Ron, Derks, Ivonne P. M., Dewald-Kaufmann, Julia F., Elders, Petra J. M., Gemke, Reinoldus J. B. J., Grievink, Linda, Hale, Lauren, Hartman, Catharina A., Heijnen, Cobi J., Huisman, Martijn, Huss, Anke, Ikram, M. Arfan, Jones, Samuel E., Velderman, Mariska Klein, Koning, Maaike, Meijer, Anne Marie, Meijer, Kim, Noordam, Raymond, Oldehinkel, Albertine J., Groeniger, Joost Oude, Penninx, Brenda W. J. H., Picavet, H. Susan J., Pieters, Sara, Reijneveld, Sijmen A., Reitz, Ellen, Renders, Carry M., Rodenburg, Gerda, Rutters, Femke, Smith, Matt C., Singh, Amika S., Snijder, Marieke B., Stronks, Karien, ten Have, Margreet, Twisk, Jos W. R., Van de Mheen, Dike, van der Ende, Jan, van der Heijden, Kristiaan B., van der Velden, Peter G., van Lenthe, Frank J., van Litsenburg, Raphaële R. L., van Oostrom, Sandra H., van Schalkwijk, Frank J., Sheehan, Connor M., Verheij, Robert A., Verhulst, Frank C., Vermeulen, Marije C. M., Vermeulen, Roel C. H., Verschuren, W. M. Monique, Vrijkotte, Tanja G. M., Wijga, Alet H., Willemen, Agnes M., ter Wolbeek, Maike, Wood, Andrew R., Xerxa, Yllza, Bramer, Wichor M., Franco, Oscar H., Luik, Annemarie I., Van Someren, Eus J. W., and Tiemeier, Henning

Published
2021
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23. How chronic are depressive and anxiety disorders? 9-year general population study using narrow and broad course outcomes

Author

ten Have, Margreet, Tuithof, Marlous, van Dorsselaer, Saskia, de Beurs, Derek, de Graaf, Ron, Batelaan, Neeltje M., Penninx, Brenda W. J. H., Macro & International Economics (ASE, FEB), ASCoR Other Research (FMG), Psychiatry, APH - Mental Health, Amsterdam Neuroscience - Complex Trait Genetics, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, and APH - Digital Health

Subjects
Diagnostic and Statistical Manual of Mental Disorders, Depressive Disorder, Major, Psychiatry and Mental health, Clinical Psychology, Disease Progression, Humans, Anxiety, Prognosis, Anxiety Disorders
Abstract

Background: Existing studies on disease course usually apply relatively short follow-up periods and narrow definitions of disease course resulting in too optimistic views on disease prognosis. This study explores the relevance of using a longer and broader (cross-disorder) perspective. Methods: Respondents with a 12-month disorder at baseline and available at 3-, 6- and 9-year follow-up were selected (major depressive disorder, MDD: n = 208; anxiety disorder: n = 220) from a general population study (N = 6646). DSM-IV disorders were assessed with the Composite International Diagnostic Interview. Disease course was described using a short and narrow perspective (i.e., 3-year follow-up, and considering presence of the index disorder only) and a long and broad perspective (9-year follow-up, and considering presence of any mood, anxiety or substance use disorder as outcome). Results: The recovery rates of both MDD and anxiety disorder reduced by half when the perspective switched from short and narrow (MDD: 74.0 %; anxiety disorder: 79.5 %) to long and broad (35.6 % and 40.0 % respectively). At 9-year follow-up, the rates of a persistent disorder (a disorder at each follow-up assessment) tripled when the perspective switched from narrow to broad (MDD: from 4.8 % to 13.9 %; anxiety disorder: from 4.5 % to 15.5 %). Limitations: The findings are not generalizable to the most severe depressed and anxious patients. Conclusions: Most people with MDD or anxiety disorder in the general population have a rather favourable prognosis when a narrow perspective is applied, but an unfavourable prognosis when a long-term and broad perspective is applied. Consequently, MDD and anxiety disorder should not merely be perceived as episodic disorders, and require longer-term disease monitoring and management.

Published
2022
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26. Depression, cardiometabolic disease, and their co-occurrence after childhood maltreatment:an individual participant data meta-analysis including over 200,000 participants

Author

Souama, Camille, Lamers, Femke, Milaneschi, Yuri, Vinkers, Christiaan H., Defina, Serena, Garvert, Linda, Stein, Frederike, Woofenden, Tom, Brosch, Katharina, Dannlowski, Udo, Galenkamp, Henrike, de Graaf, Ron, Jaddoe, Vincent W.V., Lok, Anja, van Rijn, Bas B., Völzke, Henry, Cecil, Charlotte A.M., Felix, Janine F., Grabe, Hans J., Kircher, Tilo, Lekadir, Karim, Have, Margreet ten, Walton, Esther, Penninx, Brenda W.J.H., Souama, Camille, Lamers, Femke, Milaneschi, Yuri, Vinkers, Christiaan H., Defina, Serena, Garvert, Linda, Stein, Frederike, Woofenden, Tom, Brosch, Katharina, Dannlowski, Udo, Galenkamp, Henrike, de Graaf, Ron, Jaddoe, Vincent W.V., Lok, Anja, van Rijn, Bas B., Völzke, Henry, Cecil, Charlotte A.M., Felix, Janine F., Grabe, Hans J., Kircher, Tilo, Lekadir, Karim, Have, Margreet ten, Walton, Esther, and Penninx, Brenda W.J.H.

Abstract

Background: Childhood maltreatment is associated with depression and cardiometabolic disease in adulthood. However, the relationships with these two diseases have so far only been evaluated in different samples and with different methodology. Thus, it remains unknown how the effect sizes magnitudes for depression and cardiometabolic disease compare with each other and whether childhood maltreatment is especially associated with the co-occurrence (“comorbidity”) of depression and cardiometabolic disease. This pooled analysis examined the association of childhood maltreatment with depression, cardiometabolic disease, and their comorbidity in adulthood. Methods: We carried out an individual participant data meta-analysis on 13 international observational studies (N = 217,929). Childhood maltreatment comprised self-reports of physical, emotional, and/or sexual abuse before 18 years. Presence of depression was established with clinical interviews or validated symptom scales and presence of cardiometabolic disease with self-reported diagnoses. In included studies, binomial and multinomial logistic regressions estimated sociodemographic-adjusted associations of childhood maltreatment with depression, cardiometabolic disease, and their comorbidity. We then additionally adjusted these associations for lifestyle factors (smoking status, alcohol consumption, and physical activity). Finally, random-effects models were used to pool these estimates across studies and examined differences in associations across sex and maltreatment types. Results: Childhood maltreatment was associated with progressively higher odds of cardiometabolic disease without depression (OR [95% CI] = 1.27 [1.18; 1.37]), depression without cardiometabolic disease (OR [95% CI] = 2.68 [2.39; 3.00]), and comorbidity between both conditions (OR [95% CI] = 3.04 [2.51; 3.68]) in adulthood. Post hoc analyses showed that the association with comorbidity was stronger than with either disease alone, and the associ

Published
2023

27. Prevalence, incidence, and persistence of psychotic experiences in the general population: results of a 9-year follow-up study - CORRIGENDUM

Author

Hersenen-Medisch 1, Brain, Monshouwer, Karin, Ten Have, Margreet, Tuithof, Marlous, Van Dorsselaer, Saskia, Bak, Maarten, Gunther, Nicole, Delespaul, Philippe, Van Os, Jim, De Graaf, Ron, Hersenen-Medisch 1, Brain, Monshouwer, Karin, Ten Have, Margreet, Tuithof, Marlous, Van Dorsselaer, Saskia, Bak, Maarten, Gunther, Nicole, Delespaul, Philippe, Van Os, Jim, and De Graaf, Ron

Published
2023

28. Prevalence, incidence, and persistence of psychotic experiences in the general population: Results of a 9-year follow-up study

Author

Hersenen-Medisch 1, Brain, Monshouwer, Karin, Ten Have, Margreet, Tuithof, Marlous, Van Dorsselaer, Saskia, Bak, Maarten, Gunter, Nicole, Delespaul, Philippe, Van Os, Jim, De Graaf, Ron, Hersenen-Medisch 1, Brain, Monshouwer, Karin, Ten Have, Margreet, Tuithof, Marlous, Van Dorsselaer, Saskia, Bak, Maarten, Gunter, Nicole, Delespaul, Philippe, Van Os, Jim, and De Graaf, Ron

Published
2023

29. Bidirectional relationships between cannabis use, anxiety and depressive symptoms in the mediation of the association with psychotic experience: further support for an affective pathway to psychosis

Author

Hersenen-Medisch 1, Brain, Radhakrishnan, Rajiv, Pries, Lotta-Katrin, Erzin, Gamze, Ten Have, Margreet, de Graaf, Ron, van Dorsselaer, Saskia, Gunther, Nicole, Bak, Maarten, Rutten, Bart P F, van Os, Jim, Guloksuz, Sinan, Hersenen-Medisch 1, Brain, Radhakrishnan, Rajiv, Pries, Lotta-Katrin, Erzin, Gamze, Ten Have, Margreet, de Graaf, Ron, van Dorsselaer, Saskia, Gunther, Nicole, Bak, Maarten, Rutten, Bart P F, van Os, Jim, and Guloksuz, Sinan

Published
2023

30. Age- and sex-specific associations between risk scores for schizophrenia and self-reported health in the general population

Author

Hersenen-Medisch 1, Neurogenetica, Brain, Paquin, Vincent, Pries, Lotta-Katrin, Ten Have, Margreet, Bak, Maarten, Gunther, Nicole, de Graaf, Ron, van Dorsselaer, Saskia, Lin, Bochao D, van Eijk, Kristel R, Kenis, Gunter, Richards, Alexander, O'Donovan, Michael C, Luykx, Jurjen J, Rutten, Bart P F, van Os, Jim, Shah, Jai L, Guloksuz, Sinan, Hersenen-Medisch 1, Neurogenetica, Brain, Paquin, Vincent, Pries, Lotta-Katrin, Ten Have, Margreet, Bak, Maarten, Gunther, Nicole, de Graaf, Ron, van Dorsselaer, Saskia, Lin, Bochao D, van Eijk, Kristel R, Kenis, Gunter, Richards, Alexander, O'Donovan, Michael C, Luykx, Jurjen J, Rutten, Bart P F, van Os, Jim, Shah, Jai L, and Guloksuz, Sinan

Published
2023

31. Context v. algorithm: Evidence that a transdiagnostic framework of contextual clinical characterization is of more clinical value than categorical diagnosis

Author

Hersenen-Medisch 1, Brain, TN groep Adan, Onderzoek, Neurogenetica, Van Os, Jim, Pries, Lotta Katrin, Ten Have, Margreet, De Graaf, Ron, Van Dorsselaer, Saskia, Bak, Maarten, Kenis, Gunter, Lin, Bochao D., Gunther, Nicole, Luykx, Jurjen J., Rutten, Bart P.F., Guloksuz, Sinan, Hersenen-Medisch 1, Brain, TN groep Adan, Onderzoek, Neurogenetica, Van Os, Jim, Pries, Lotta Katrin, Ten Have, Margreet, De Graaf, Ron, Van Dorsselaer, Saskia, Bak, Maarten, Kenis, Gunter, Lin, Bochao D., Gunther, Nicole, Luykx, Jurjen J., Rutten, Bart P.F., and Guloksuz, Sinan

Published
2023

38. Bidirectional relationships between cannabis use, anxiety and depressive symptoms in the mediation of the association with psychotic experience: further support for an affective pathway to psychosis.

Author

Radhakrishnan, Rajiv, Pries, Lotta-Katrin, Erzin, Gamze, ten Have, Margreet, de Graaf, Ron, van Dorsselaer, Saskia, Gunther, Nicole, Bak, Maarten, Rutten, Bart P. F., van Os, Jim, and Guloksuz, Sinan

Subjects
CANNABIS (Genus), PSYCHOSES, MULTIPLE regression analysis, MENTAL depression, FACTOR analysis, DESCRIPTIVE statistics, RESEARCH funding, ANXIETY, DATA analysis software, LONGITUDINAL method
Abstract

Background: Empirical evidence suggests that people use cannabis to ameliorate anxiety and depressive symptoms, yet cannabis also acutely worsens psychosis and affective symptoms. However, the temporal relationship between cannabis use, anxiety and depressive symptoms and psychotic experiences (PE) in longitudinal studies is unclear. This may be informed by examination of mutually mediating roles of cannabis, anxiety and depressive symptoms in the emergence of PE. Methods: Data were derived from the second longitudinal Netherlands Mental Health Survey and Incidence Study. Mediation analysis was performed to examine the relationship between cannabis use, anxiety/depressive symptoms and PE, using KHB logit in STATA while adjusting for age, sex and education status. Results: Cannabis use was found to mediate the relationship between preceding anxiety, depressive symptoms and later PE incidence, but the indirect contribution of cannabis use was small (for anxiety: % of total effect attributable to cannabis use = 1.00%; for depression: % of total effect attributable to cannabis use = 1.4%). Interestingly, anxiety and depressive symptoms were found to mediate the relationship between preceding cannabis use and later PE incidence to a greater degree (% of total effect attributable to anxiety = 17%; % of total effect attributable to depression = 37%). Conclusion: This first longitudinal cohort study examining the mediational relationship between cannabis use, anxiety/depressive symptoms and PE, shows that there is a bidirectional relationship between cannabis use, anxiety/depressive symptoms and PE. However, the contribution of anxiety/depressive symptoms as a mediator was greater than that of cannabis. [ABSTRACT FROM AUTHOR]

Published
2023
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47. Additional file 1 of Depression, cardiometabolic disease, and their co-occurrence after childhood maltreatment: an individual participant data meta-analysis including over 200,000 participants

Author

Souama, Camille, Lamers, Femke, Milaneschi, Yuri, Vinkers, Christiaan H., Defina, Serena, Garvert, Linda, Stein, Frederike, Woofenden, Tom, Brosch, Katharina, Dannlowski, Udo, Galenkamp, Henrike, de Graaf, Ron, Jaddoe, Vincent W. V., Lok, Anja, van Rijn, Bas B., Völzke, Henry, Cecil, Charlotte A. M., Felix, Janine F., Grabe, Hans J., Kircher, Tilo, Lekadir, Karim, Have, Margreet ten, Walton, Esther, and Penninx, Brenda W. J. H.

Abstract

Additional file 1. Section 1. ALSPAC participants. Section 2. GenR additional information. Section 3. R-script of analyses. Section 4. Imputation of lifestyle variables. Section 5. Associations with current vs. lifetime depression diagnoses. TableS1. Childhood maltreatment assessment overview. Table S2. Depressionassessment overview. Table S3. Definition of cardiovascular disease. Table S4. Alcohol consumption and physical activity assessment overview. Table S5. Pooled associations of childhood maltreatment with comorbidity status after adjusting for lifestyle factors (model 4), according to three different imputation strategies. Table S6. Overview of cohorts included in each meta-analyzed model. Table S7. Number of cases, weights and odds ratios of thecohorts in meta-analyzed model 3. Table S8. Results of meta-analyzed model 3 per subgroup of studies based on depression assessment type.

Published
2023
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50. The descriptive epidemiology of DSM-IV Adult ADHD in the World Health Organization World Mental Health Surveys

Author

Fayyad, John, Sampson, Nancy A., Hwang, Irving, Adamowski, Tomasz, Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Andrade, Laura H. S. G., Borges, Guilherme, de Girolamo, Giovanni, Florescu, Silvia, Gureje, Oye, Haro, Josep Maria, Hu, Chiyi, Karam, Elie G., Lee, Sing, Navarro-Mateu, Fernando, O’Neill, Siobhan, Pennell, Beth-Ellen, Piazza, Marina, Posada-Villa, José, ten Have, Margreet, Torres, Yolanda, Xavier, Miguel, Zaslavsky, Alan M., Kessler, Ronald C., Adamowski, Tomasz, Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Al-Kaisy, Mohammad, Subaie, Abdullah Al, Alonso, Jordi, Altwaijri, Yasmin, Andrade, Laura Helena, Atwoli, Lukoye, Auerbach, Randy P., Axinn, William G., Benjet, Corina, Borges, Guilherme, Bossarte, Robert M., Bromet, Evelyn J., Bruffaerts, Ronny, Bunting, Brendan, Caffo, Ernesto, de Almeida, Jose Miguel Caldas, Cardoso, Graca, Cia, Alfredo H., Chardoul, Stephanie, Chatterji, Somnath, Filho, Alexandre Chiavegatto, Cuijpers, Pim, Degenhardt, Louisa, de Girolamo, Giovanni, de Graaf, Ron, de Jonge, Peter, Demyttenaere, Koen, Ebert, David D., Evans-Lacko, Sara, Fayyad, John, Fiestas, Fabian, Florescu, Silvia, Forresi, Barbara, Galea, Sandro, Germine, Laura, Gilman, Stephen E., Ghimire, Dirgha J., Glantz, Meyer D., Gureje, Oye, Haro, Josep Maria, He, Yanling, Hinkov, Hristo, Hu, Chi-yi, Huang, Yueqin, Karam, Aimee Nasser, Karam, Elie G., Kawakami, Norito, Kessler, Ronald C., Kiejna, Andrzej, Koenen, Karestan C., Kovess-Masfety, Viviane, Lago, Luise, Lara, Carmen, Lee, Sing, Lepine, Jean-Pierre, Levav, Itzhak, Levinson, Daphna, Liu, Zhaorui, Martins, Silvia S., Matschinger, Herbert, McGrath, John J., McLaughlin, Katie A., Medina-Mora, Maria Elena, Mneimneh, Zeina, Moskalewicz, Jacek, Murphy, Samuel D., Navarro-Mateu, Fernando, Nock, Matthew K., O’Neill, Siobhan, Oakley-Browne, Mark, Hans Ormel, J., Pennell, Beth-Ellen, Piazza, Marina, Pinder-Amaker, Stephanie, Piotrowski, Patryk, Posada-Villa, Jose, Ruscio, Ayelet M., Scott, Kate M., Shahly, Vicki, Silove, Derrick, Slade, Tim, Smoller, Jordan W., Stagnaro, Juan Carlos, Stein, Dan J., Street, Amy E., Tachimori, Hisateru, Taib, Nezar, Have, Margreet ten, Thornicroft, Graham, Torres, Yolanda, Viana, Maria Carmen, Vilagut, Gemma, Wells, Elisabeth, Williams, David R., Williams, Michelle A., Wojtyniak, Bogdan, Zaslavsky, Alan M., and on behalf of the WHO World Mental Health Survey Collaborators

Published
2017
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