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203 results on '"de Gonzalez, A. Berrington"'

2. Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction

Author

Yiangou, Kristia, Mavaddat, Nasim, Dennis, Joe, Zanti, Maria, Wang, Qin, Bolla, Manjeet K., Abubakar, Mustapha, Ahearn, Thomas U., Andrulis, Irene L., Anton-Culver, Hoda, Antonenkova, Natalia N., Arndt, Volker, Aronson, Kristan J., Augustinsson, Annelie, Baten, Adinda, Behrens, Sabine, Bermisheva, Marina, de Gonzalez, Amy Berrington, Białkowska, Katarzyna, Boddicker, Nicholas, Bodelon, Clara, Bogdanova, Natalia V., Bojesen, Stig E., Brantley, Kristen D., Brauch, Hiltrud, Brenner, Hermann, Camp, Nicola J., Canzian, Federico, Castelao, Jose E., Cessna, Melissa H., Chang-Claude, Jenny, Chenevix-Trench, Georgia, Chung, Wendy K., Colonna, Sarah V., Couch, Fergus J., Cox, Angela, Cross, Simon S., Czene, Kamila, Daly, Mary B., Devilee, Peter, Dörk, Thilo, Dunning, Alison M., Eccles, Diana M., Eliassen, A. Heather, Engel, Christoph, Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter A., Fletcher, Olivia, Flyger, Henrik, Fritschi, Lin, Gago-Dominguez, Manuela, Gentry-Maharaj, Aleksandra, González-Neira, Anna, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A., Hamann, Ute, Hartikainen, Jaana M., Ho, Vikki, Hodge, James, Hollestelle, Antoinette, Honisch, Ellen, Hooning, Maartje J., Hoppe, Reiner, Hopper, John L., Howell, Sacha, Howell, Anthony, Jakovchevska, Simona, Jakubowska, Anna, Jernström, Helena, Johnson, Nichola, Kaaks, Rudolf, Khusnutdinova, Elza K., Kitahara, Cari M., Koutros, Stella, Kristensen, Vessela N., Lacey, James V., Lambrechts, Diether, Lejbkowicz, Flavio, Lindblom, Annika, Lush, Michael, Mannermaa, Arto, Mavroudis, Dimitrios, Menon, Usha, Murphy, Rachel A., Nevanlinna, Heli, Obi, Nadia, Offit, Kenneth, Park-Simon, Tjoung-Won, Patel, Alpa V., Peng, Cheng, Peterlongo, Paolo, Pita, Guillermo, Plaseska-Karanfilska, Dijana, Pylkäs, Katri, Radice, Paolo, Rashid, Muhammad U., Rennert, Gad, Roberts, Eleanor, Rodriguez, Juan, Romero, Atocha, Rosenberg, Efraim H., Saloustros, Emmanouil, Sandler, Dale P., Sawyer, Elinor J., Schmutzler, Rita K., Scott, Christopher G., Shu, Xiao-Ou, Southey, Melissa C., Stone, Jennifer, Taylor, Jack A., Teras, Lauren R., van de Beek, Irma, Willett, Walter, Winqvist, Robert, Zheng, Wei, Vachon, Celine M., Schmidt, Marjanka K., Hall, Per, MacInnis, Robert J., Milne, Roger L., Pharoah, Paul D. P., Simard, Jacques, Antoniou, Antonis C., Easton, Douglas F., and Michailidou, Kyriaki

Published
2024
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3. Moving towards FAIR practices in epidemiological research

Author

Garcia-Closas, Montserrat, Ahearn, Thomas U., Gaudet, Mia M., Hurson, Amber N., Balasubramanian, Jeya Balaji, Choudhury, Parichoy Pal, Gerlanc, Nicole M., Patel, Bhaumik, Russ, Daniel, Abubakar, Mustapha, Freedman, Neal D., Wong, Wendy S. W., Chanock, Stephen J., de Gonzalez, Amy Berrington, and Almeida, Jonas S

Subjects
Quantitative Biology - Populations and Evolution
Abstract

Reproducibility and replicability of research findings are central to the scientific integrity of epidemiology. In addition, many research questions require combiningdata from multiple sources to achieve adequate statistical power. However, barriers related to confidentiality, costs, and incentives often limit the extent and speed of sharing resources, both data and code. Epidemiological practices that follow FAIR principles can address these barriers by making resources (F)indable with the necessary metadata , (A)ccessible to authorized users and (I)nteroperable with other data, to optimize the (R)e-use of resources with appropriate credit to its creators. We provide an overview of these principles and describe approaches for implementation in epidemiology. Increasing degrees of FAIRness can be achieved by moving data and code from on-site locations to the Cloud, using machine-readable and non-proprietary files, and developing open-source code. Adoption of these practices will improve daily work and collaborative analyses, and facilitate compliance with data sharing policies from funders and scientific journals. Achieving a high degree of FAIRness will require funding, training, organizational support, recognition, and incentives for sharing resources. But these costs are amply outweighed by the benefits of making research more reproducible, impactful, and equitable by facilitating the re-use of precious research resources by the scientific community.

Published
2022

11. Interpretation of interaction: A review

Author

de González, Amy Berrington and Cox, D. R.

Subjects
Statistics - Applications
Abstract

Several different types of statistical interaction are defined and distinguished, primarily on the basis of the nature of the factors defining the interaction. Illustrative examples, mostly epidemiological, are given. The emphasis is primarily on interpretation rather than on methods for detecting interactions., Comment: Published in at http://dx.doi.org/10.1214/07-AOAS124 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org)

Published
2007
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12. Association between Class III Obesity (BMI of 40–59 kg/m2) and Mortality: A Pooled Analysis of 20 Prospective Studies

Author

Kitahara, Cari M, Flint, Alan J, de Gonzalez, Amy Berrington, Bernstein, Leslie, Brotzman, Michelle, MacInnis, Robert J, Moore, Steven C, Robien, Kim, Rosenberg, Philip S, Singh, Pramil N, Weiderpass, Elisabete, Adami, Hans Olov, Anton-Culver, Hoda, Ballard-Barbash, Rachel, Buring, Julie E, Freedman, D Michal, Fraser, Gary E, Freeman, Laura E Beane, Gapstur, Susan M, Gaziano, John Michael, Giles, Graham G, Håkansson, Niclas, Hoppin, Jane A, Hu, Frank B, Koenig, Karen, Linet, Martha S, Park, Yikyung, Patel, Alpa V, Purdue, Mark P, Schairer, Catherine, Sesso, Howard D, Visvanathan, Kala, White, Emily, Wolk, Alicja, Zeleniuch-Jacquotte, Anne, and Hartge, Patricia

Subjects
Epidemiology, Biomedical and Clinical Sciences, Public Health, Health Sciences, Nutrition, Clinical Trials and Supportive Activities, Pneumonia & Influenza, Obesity, Clinical Research, Aging, Prevention, Cancer, Stroke, Cardiovascular, Metabolic and endocrine, Good Health and Well Being, Australia, Body Mass Index, Humans, Life Expectancy, Prospective Studies, Risk Factors, Sweden, United States, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

BackgroundThe prevalence of class III obesity (body mass index [BMI]≥40 kg/m2) has increased dramatically in several countries and currently affects 6% of adults in the US, with uncertain impact on the risks of illness and death. Using data from a large pooled study, we evaluated the risk of death, overall and due to a wide range of causes, and years of life expectancy lost associated with class III obesity.Methods and findingsIn a pooled analysis of 20 prospective studies from the United States, Sweden, and Australia, we estimated sex- and age-adjusted total and cause-specific mortality rates (deaths per 100,000 persons per year) and multivariable-adjusted hazard ratios for adults, aged 19-83 y at baseline, classified as obese class III (BMI 40.0-59.9 kg/m2) compared with those classified as normal weight (BMI 18.5-24.9 kg/m2). Participants reporting ever smoking cigarettes or a history of chronic disease (heart disease, cancer, stroke, or emphysema) on baseline questionnaires were excluded. Among 9,564 class III obesity participants, mortality rates were 856.0 in men and 663.0 in women during the study period (1976-2009). Among 304,011 normal-weight participants, rates were 346.7 and 280.5 in men and women, respectively. Deaths from heart disease contributed largely to the excess rates in the class III obesity group (rate differences = 238.9 and 132.8 in men and women, respectively), followed by deaths from cancer (rate differences = 36.7 and 62.3 in men and women, respectively) and diabetes (rate differences = 51.2 and 29.2 in men and women, respectively). Within the class III obesity range, multivariable-adjusted hazard ratios for total deaths and deaths due to heart disease, cancer, diabetes, nephritis/nephrotic syndrome/nephrosis, chronic lower respiratory disease, and influenza/pneumonia increased with increasing BMI. Compared with normal-weight BMI, a BMI of 40-44.9, 45-49.9, 50-54.9, and 55-59.9 kg/m2 was associated with an estimated 6.5 (95% CI: 5.7-7.3), 8.9 (95% CI: 7.4-10.4), 9.8 (95% CI: 7.4-12.2), and 13.7 (95% CI: 10.5-16.9) y of life lost. A limitation was that BMI was mainly ascertained by self-report.ConclusionsClass III obesity is associated with substantially elevated rates of total mortality, with most of the excess deaths due to heart disease, cancer, and diabetes, and major reductions in life expectancy compared with normal weight. Please see later in the article for the Editors' Summary.

Published
2014

15. Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

Author

Di Angelantonio, Emanuele, Bhupathiraju, Shilpa N, Wormser, David, Gao, Pei, Kaptoge, Stephen, de Gonzalez, Amy Berrington, Cairns, Benjamin J, Huxley, Rachel, Jackson, Chandra L, Joshy, Grace, Lewington, Sarah, Manson, JoAnn E, Murphy, Neil, Patel, Alpa V, Samet, Jonathan M, Woodward, Mark, Zheng, Wei, Zhou, Maigen, Bansal, Narinder, Barricarte, Aurelio, Carter, Brian, Cerhan, James R, Collins, Rory, Smith, George Davey, Fang, Xianghua, Franco, Oscar H, Green, Jane, Halsey, Jim, Hildebrand, Janet S, Jung, Keum Ji, Korda, Rosemary J, McLerran, Dale F, Moore, Steven C, O'Keeffe, Linda M, Paige, Ellie, Ramond, Anna, Reeves, Gillian K, Rolland, Betsy, Sacerdote, Carlotta, Sattar, Naveed, Sofianopoulou, Eleni, Stevens, June, Thun, Michael, Ueshima, Hirotsugu, Yang, Ling, Yun, Young Duk, Willeit, Peter, Banks, Emily, Beral, Valerie, Chen, Zhengming, Gapstur, Susan M, Gunter, Marc J, Hartge, Patricia, Jee, Sun Ha, Lam, Tai-Hing, Peto, Richard, Potter, John D, Willett, Walter C, Thompson, Simon G, Danesh, John, and Hu, Frank B

Published
2016
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16. epiDonate – distributed serverless data infrastructure for epidemiological studies

Author

Almeida, Jonas S, Patel, Bhaumik, Russ, Daniel E, Bhawsar, Praphulla, Maurice, Pedro F Saint, Matthews, Charles, Anand, Adit, Ferguson, Martin, Johnson, Davin, Brotzman, Michelle, Gerlanc, Nicole, Chanock, Stephen, de Gonzalez, Amy Berrington, Gaudet, Mia, and Garcia-Closas, Montserrat

Subjects
Articles
Abstract

Motivation: Epidemiological studies face two important challenges: the need to ingest ever more complex data types, and mounting concerns about participant privacy and data governance. These two challenges are compounded by the expectation that data infrastructure will eventually need to facilitate cross-registration of participants by multiple epidemiological studies. Implementation: The portable web-service epiDonate was developed using the serverless model known as FaaS (Function-as-a-Service). The reference implementation uses nodejs. The implementation relies on a simple tokenization scheme, mediated by a public API, that a) distinguishes admin from participant roles, with b) extensible permission configuration operating a read/write structure. General Features: The critical design feature of epiDonate is the absence of business logic on the server-side (the web service). The simplicity removes the need to customize virtual machines and enables ecosystems of multiple web Applications backed by one or more data donation deployments. Availability: https://episphere.github.io/donate

Published
2023

17. Supplementary Figure 1 from Pooling Prospective Studies to Investigate the Etiology of Second Cancers

Author

Black, Amanda, primary, Gibson, Todd M., primary, Shiels, Meredith S., primary, Park, Yikyung, primary, Robien, Kim, primary, Albanes, Demetrius, primary, Weinstein, Stephanie J., primary, Freeman, Laura E. Beane, primary, Andreotti, Gabriella, primary, Purdue, Mark P., primary, Fraumeni, Joseph F., primary, Hartge, Patricia, primary, Tucker, Margaret A., primary, Hoover, Robert N., primary, Cerhan, James R., primary, Zeleniuch-Jacquotte, Anne, primary, Curtis, Rochelle E., primary, Elena, Joanne, primary, Sampson, Joshua N., primary, de Gonzalez, Amy Berrington, primary, and Morton, Lindsay M., primary

Published
2023
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18. Data from Pooling Prospective Studies to Investigate the Etiology of Second Cancers

Author

Black, Amanda, primary, Gibson, Todd M., primary, Shiels, Meredith S., primary, Park, Yikyung, primary, Robien, Kim, primary, Albanes, Demetrius, primary, Weinstein, Stephanie J., primary, Freeman, Laura E. Beane, primary, Andreotti, Gabriella, primary, Purdue, Mark P., primary, Fraumeni, Joseph F., primary, Hartge, Patricia, primary, Tucker, Margaret A., primary, Hoover, Robert N., primary, Cerhan, James R., primary, Zeleniuch-Jacquotte, Anne, primary, Curtis, Rochelle E., primary, Elena, Joanne, primary, Sampson, Joshua N., primary, de Gonzalez, Amy Berrington, primary, and Morton, Lindsay M., primary

Published
2023
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21. Supplementary Tables 1 - 3 from Pooling Prospective Studies to Investigate the Etiology of Second Cancers

Author

Black, Amanda, primary, Gibson, Todd M., primary, Shiels, Meredith S., primary, Park, Yikyung, primary, Robien, Kim, primary, Albanes, Demetrius, primary, Weinstein, Stephanie J., primary, Freeman, Laura E. Beane, primary, Andreotti, Gabriella, primary, Purdue, Mark P., primary, Fraumeni, Joseph F., primary, Hartge, Patricia, primary, Tucker, Margaret A., primary, Hoover, Robert N., primary, Cerhan, James R., primary, Zeleniuch-Jacquotte, Anne, primary, Curtis, Rochelle E., primary, Elena, Joanne, primary, Sampson, Joshua N., primary, de Gonzalez, Amy Berrington, primary, and Morton, Lindsay M., primary

Published
2023
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22. Moving towards FAIR practices in epidemiological research

Author

García-Closas, Montserrat, primary, Ahearn, Thomas U, additional, Gaudet, Mia M, additional, Hurson, Amber N, additional, Balasubramanian, Jeya Balaji, additional, Choudhury, Parichoy Pal, additional, Gerlanc, Nicole M, additional, Patel, Bhaumik, additional, Russ, Daniel, additional, Abubakar, Mustapha, additional, Freedman, Neal D, additional, Wong, Wendy S W, additional, Chanock, Stephen J, additional, de Gonzalez, Amy Berrington, additional, and Almeida, Jonas S, additional

Published
2023
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27. Correction to: The influence of treatment on hormone receptor subgroups and breast cancer-specific mortality within US integrated healthcare systems

Author

Ramin, Cody, primary, Gierach, Gretchen L., additional, Abubakar, Mustapha, additional, Veiga, Lene H. S., additional, Vo, Jacqueline B., additional, Curtis, Rochelle E., additional, Bowles, Erin J. Aiello, additional, Feigelson, Heather Spencer, additional, Buist, Diana S. M., additional, de Gonzalez, Amy Berrington, additional, and Bodelon, Clara, additional

Published
2022
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36. Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts

Author

Jiao, Li, de Gonzalez, Amy Berrington, Hartge, Patricia, Pfeiffer, Ruth M., Park, Yikyung, Freedman, D. Michal, Gail, Mitchell H., Alavanja, Michael C. R., Albanes, Demetrius, Freeman, Laura E. Beane, Chow, Wong-Ho, Huang, Wen-Yi, Hayes, Richard B., Hoppin, Jane A., Ji, Bu-tian, Leitzmann, Michael F., Linet, Martha S., Meinhold, Cari L., Schairer, Catherine, Schatzkin, Arthur, Virtamo, Jarmo, Weinstein, Stephanie J., Zheng, Wei, and Stolzenberg-Solomon, Rachael Z.

Published
2010

42. Abstract PO-192: Comparing the association of self-reported race-ethnicity and genetic ancestry with all-cause mortality: A pan-cancer survivor analysis in the PLCO Screening Trial

Author

Brown, Derek W., primary, Vo, Jacqueline B, additional, Buller, Ian D., additional, Synnott, Naoise C., additional, Jones, Rena R., additional, Landi, Maria Teresa, additional, Huang, Wen-Yi, additional, Machiela, Mitchell J., additional, de Gonzalez, Amy Berrington, additional, and Freedman, Neal D., additional

Published
2022
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43. Treatment-Related Thoracic Soft Tissue Sarcomas in Two US Cohorts of Breast Cancer Survivors

Author

Veiga, Lene H.S., primary, Vo, Jacqueline B., additional, Curtis, Rochelle E., additional, Mille, Matthew M., additional, Lee, Choonsik, additional, Ramin, Cody, additional, Bodelon, Clara, additional, Bowles, Erin J. Aiello, additional, Buist, Diana SM, additional, Weinmann, Sheila, additional, Feigelson, Heather Spencer, additional, Gierach, Gretchen L., additional, and de Gonzalez, Amy Berrington, additional

Published
2022
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44. Body-mass index and mortality among 1.46 million white adults

Author

de Gonzalez, Amy Berrington, Hartge, Patricia, Cerhan, James R., Flint, Alan J., Hannan, Lindsay, MacInnis, Robert J., Moore, Steven C., Tobias, Geoffrey S., Anton-Culver, Hoda, Freeman, Laura Beane, Beeson, W. Lawrence, Clipp, Sandra L., English, Dallas R., Folsom, Aaron R., Freedman, Michal, Giles, Graham, Hakansson, Niclas, Henderson, Katherine D., Hoffman-Bolton, Judith, Hoppin, Jane A., Koenig, Karen L., I-Min Lee, Linet, Martha S., Yikyung Park, Sesso, Howard D., Weiderpass, Elisabete, Willcox, Bradley J., Pocobelli, Gaia, Schatzkin, Arthur, Wolk, Alicja, Zeleniuch-Jacquotte, Anne, Willett, Walter C., and Thun, Michael J.

Subjects
Mortality -- United States, Mortality -- Risk factors, Obesity -- Risk factors, Body mass index -- Measurement, Body mass index -- Health aspects
Abstract

The optimal body-mass index (BMI) range is assessed and has provided stable estimates of the risks associated with being overweight, obese, and morbidly obese, with minimal confounding due to smoking or prevalent disease. The studies have shown that for non-Hispanic whites, both overweight and obesity are associated with increased all-cause mortality and also underweight.

Published
2010

45. Benefits and Harms of Computed Tomography Lung Cancer Screening Strategies: A Comparative Modeling Study for the U.S. Preventive Services Task Force

Author

de Koning, Harry J., Meza, Rafael, Plevritis, Sylvia K., ten Haaf, Kevin, Munshi, Vidit N., Jeon, Jihyoun, Erdogan, Saadet Ayca, Kong, Chung Yin, Han, Summer S., van Rosmalen, Joost, Choi, Sung Eun, Pinsky, Paul F., de Gonzalez, Amy Berrington, Berg, Christine D., Black, William C., Tammemägi, Martin C., Hazelton, William D., Feuer, Eric J., and McMahon, Pamela M.

Published
2014

46. A Pooled Analysis of Waist Circumference and Mortality in 650,000 Adults

Author

Cerhan, James R., Moore, Steven C., Jacobs, Eric J., Kitahara, Cari M., Rosenberg, Philip S., Adami, Hans-Olov, Ebbert, Jon O., English, Dallas R., Gapstur, Susan M., Giles, Graham G., Horn-Ross, Pamela L., Park, Yikyung, Patel, Alpa V., Robien, Kim, Weiderpass, Elisabete, Willett, Walter C., Wolk, Alicja, Zeleniuch-Jacquotte, Anne, Hartge, Patricia, Bernstein, Leslie, and de Gonzalez, Amy Berrington

Published
2014
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47. Abstract PO-055: Molecular characterization of papillary thyroid cancer in relation to ionizing radiation dose following the Chernobyl accident

Author

Morton, Lindsay M., primary, Karyadi, Danielle, additional, Stewart, Chip, additional, Bogdanova, Tetiana, additional, Dawson, Eric, additional, Steinberg, Mia, additional, Dai, Jieqiong, additional, Hartley, Stephen, additional, Schonfeld, Sara, additional, Sampson, Joshua, additional, Maruvka, Yosi, additional, Kapoor, Vidushi, additional, Ramsden, Dale, additional, Carvajal-Garcia, Juan, additional, Perou, Chuck, additional, Parker, Joel, additional, Krznaric, Marko, additional, Yeager, Meredith, additional, Boland, Joseph, additional, Hutchinson, Amy, additional, Hicks, Belynda, additional, Dagnall, Casey, additional, Gastier-Foster, Julie, additional, Bowen, Jay, additional, Lee, Olivia, additional, Machiela, Mitchell, additional, Cahoon, Elizabeth, additional, Brenner, Alina, additional, Mabuchi, Kiyohiko, additional, Drozdovitch, Vladimir, additional, Masiuk, Sergii, additional, Chepurny, Mykola, additional, Zurnadzhy, Liudmyla Yu, additional, Hatch, Maureen, additional, de Gonzalez, Amy Berrington, additional, Thomas, Gerry, additional, Tronko, Mykola, additional, Getz, Gad, additional, and Chanock, Stephen, additional

Published
2021
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