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Background: To assess the incidence of suicides among Brazilian Federal Highway Police Officers (FHPO) between 2001 and 2020, as well as to describe their sociodemographic and occupational profile., Methods: A retrospective study analyzed all suicides among FHPO of all Brazilian states between 2001 and 2020 based on personalized police record files., Results: The average suicide rate was 18.7/100,000 persons per year. A total of 35 suicides were identified, of which 33 (91.4%) were by firearm. Most FHPO who died by suicide were male (94.3%), under the age of 40 (62.9%), working for 10 or more years (57.1%), married (65.7%), parents (68.6%), had health insurance (77.1%), and worked in alternating shifts (54.2%)., Conclusion: The suicide rate among FHPO is high. Due to missing data on age and gender, standardized rates were not reported in the current study, therefore a careful interpretation of the rates reported should be considered., (© 2023 Wiley Periodicals LLC.)

The petroleum industry generates a range of wastes which is often are disposed in soil close to the well location, negatively affecting soil and water quality. The objective of this study was to evaluate the solubility and map the spatial variability of barium in a potentially contaminated area. The study area consisted of a petroleum well-drilling waste disposal site located in the municipality of Mato Rico-PR. A large georeferenced sampling grid was organized. Soil samples were collected at depths of 30, 60, 90, and 120 cm for determination of the "pseudo-total" concentrations and geochemical fractionation of barium. The barium concentrations showed spatial dependence, which permitted the use of geostatistical interpolators. Regarding depth, the depth of 0-30 cm showed the largest contaminated area; however, higher concentrations of barium were found at the depth of 60-90 cm. The results of geochemical fractionation showed that the analyzed samples contained percentages higher than 99% in the non-labile fraction (residual). These results indicate clearly that the barium was in a condition of low solubility, even for samples that had the highest concentrations, presenting low-environmental risk.

The scope of this paper was to assess the health level in Brazilian states using the Health Development Index (HDI). The HDI consisted of the following dimensions: (1) Health resources: Availability and quality of health resources; (2) Primary Healthcare coverage and sanitation; (3) Effectiveness of health policies. Each dimension was composed of a set of indicators obtained from national databases. In 2005, Brazil had an intermediate level of development of health, having progressed from a low level in 1999. Most states had medium and low development, with deficits in resources and coverage. The dimension of effectiveness was highly developed nationwide. With the construction of a synthetic indicator (HDI) it was possible to detect that in most of the country there are severe deficiencies in the availability and quality of health resources. These results can help health managers to tackle the challenge of making public health universal.

Background: Eosinophil accumulation and activation are characteristic features of inflammation in allergic diseases and in host defense against parasites., Goals: To investigate the involvement of eosinophils in inflamed and noninflamed mucosa of patients with inflammatory bowel disease (IBD)., Study: Specimens of inflamed colonic mucosa from 15 patients with ulcerative colitis (UC) and inflamed and noninflamed colonic mucosa from 15 patients with Crohn's disease (CD) were submitted to histologic and immunohistochemical studies. Twelve patients with irritable bowel syndrome were studied as controls. Sirius red was used to label eosinophils in tissue. EG1, EG2, and anti-hIL-5 were used as primary antibodies in an indirect alkaline phosphatase-labeled immunostaining protocol. Both positive and negative lamina propria cells were assessed by a quantitative grading system and the results expressed as cell numbers per mm., Results: Increased proportions of eosinophils stained with Sirius red, EG1, EG2, and anti-hIL-5+ cells were found in the colon of patients with UC and in inflamed and noninflamed colon of CD patients as compared with controls. Crohn's disease patients showed increased proportions of EG1+ and EG2+ cells as compared with those with UC. Increased proportions of IL-5+ cells were detected in UC patients as compared with those with CD., Conclusion: Quantitative eosinophil alterations and IL-5+ cells may indicate enhanced cellular activation with degranulation, which is implicated in the pathogenesis of IBD. Increase in IL-5+ cells may reflect a predominant local Th2 response in UC as compared with CD.