123 results on '"de Castro, S. M. M."'
Search Results
2. Dutch Nationwide Cohort Experience with a New PROMs Set in Metabolic and Bariatric Surgery: BODY-Q Obesity Module.
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Nienhuijs, Simon W., Bruinsma, Floris, Schouten, Ruben, Hoogbergen, Maarten M., Cnossen, Nienke G., Gernette, Chantal, van Rossum, Elisabeth F. C., de Vries, Claire E. E., Monpellier, Valery M., Klassen, Anne F., Pusic, Andrea L., Liem, Ronald S. L., Acker, G. J. D., Apers, J. A., de Castro, S. M. M., Damen, S. L., Faneyte, I. F., Göttgens, K., Greve, J. W. M., and Hof, G.van't
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PHYSICAL mobility ,BODY image ,QUALITY of life ,BARIATRIC surgery ,REGRESSION analysis - Abstract
Purpose: Patient-reported outcomes are important as obesity is a chronic disease with a substantial impact. A multidisciplinary task force selected six scales (48 questions) from the validated BODY-Q questionnaire. This subset was gradually introduced and evaluated in a mandatory nationwide registry. The focus was to assess the scale's module results and its feasibility in a quality registry. Materials and Methods: All Dutch patients undergoing bariatric surgery between 2019 and 2022 were selected. Completed questionnaires of RAND-36, EQ-5D-5L, and BODY-Q were reviewed with baseline and 1-year results. Uni- and multivariable regression analyses were performed to assess the relationship between baseline characteristics and quality of life scores over time. Results: A total of 10,972 patients completed at least one BODY-Q scale. The lowest score was on the body image scale preoperatively (28.2, SD 20.9) and the highest on the social scale postoperatively (76.2, SD 18.8). A representative group of 510 patients with repeated measurements showed the most improvement on the body image scale (+ 32.2) followed by physical function (+ 26.3). Multivariable linear regression analysis showed a significant influence, primarily for gender, age, and BMI on BODY-Q scores. Score improvement for BODY-Q was mainly driven by weight loss, while EQ-5D-5L and RAND-36 showed no clear pattern. Comparing the three questionnaires showed significant correlations for physical and social function only. Conclusion: The BODY-Q obesity module demonstrates potential as a relevant PROM for inclusion in a quality registry. BODY-Q scores provide a foundation for future research, with notable improvements in quality of life observed, particularly in the body image and physical function scales. [ABSTRACT FROM AUTHOR]
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- 2025
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3. Marginal Ulceration After (Laparoscopic) Roux-en-Y Gastric Bypass: Pathophysiology, Diagnostics, Treatment, and Prevention
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Coblijn, U. K., van Wagensveld, B. A., Lagarde, S. M., de Castro, S. M. M., Ettinger, João, editor, Ázaro, Euler, editor, Weiner, Rudolf, editor, Higa, Kelvin D., editor, Galvão Neto, Manoel, editor, Fernandes Teixeira, Andre, editor, and Jawad, Muhammad, editor
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- 2020
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4. The Impact of Longer Biliopancreatic Limb Length on Weight Loss and Comorbidity Improvement at 5 Years After Primary Roux-en-Y Gastric Bypass Surgery: A Population-Based Matched Cohort Study.
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Bruinsma, Floris F. E., Nienhuijs, Simon W., Liem, Ronald S. L., Greve, Jan Willem M., Marang-van de Mheen, Perla J., van Acker, G. J. D., Apers, J., de Brauw, L. M., de Castro, S. M. M., Damen, S. L., Faneyte, I. F., van' t Hof, G., Jonker, F. H. W., Klaassen, R. A., Lagae, E. A. G. L., Langenhoff, B. S., Liem, R. S. L., Luijten, A. A. P. M., Nienhuijs, S. W., and Smeenk, R. M.
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PROPENSITY score matching ,WEIGHT loss ,GASTRIC bypass ,ODDS ratio ,LOGISTIC regression analysis ,CONFIDENCE intervals - Abstract
Introduction: Different limb lengths are used in Roux-en-Y gastric bypass (RYGB) surgery, as there is no consensus which limb length strategy has the best outcomes. The biliopancreatic limb (BPL) is thought to play an important role in achieving weight loss and associated comorbidity resolution. The objective of this study was to assess the impact of a longer BPL on weight loss and comorbidity improvement at 5 years after primary RYGB. Methods: All patients aged ≥ 18 years undergoing primary RYGB between 2014–2017 with registered follow-up 5 years after surgery were included. Long BPL was defined as BPL ≥ 100 cm and short BPL as BPL < 100 cm. The primary outcome was achieving at least 25% total weight loss (TWL) at 5 years. Secondary outcomes included absolute %TWL and improvement of comorbidities. A propensity score matched logistic and linear regression was used to estimate the difference in outcomes between patients with long and short BPL. Results: At 5 years, long BPL had higher odds to achieve ≥ 25% TWL (odds ratio (OR) 1.19, 95% confidence interval (CI) [1.01 – 1.41]) and was associated with 1.26% higher absolute TWL (β = 1.26, 95% CI [0.53 – 1.99]). Furthermore, long BPL was more likely to result in improved diabetes mellitus (OR = 2.17, 95% CI [1.31 – 3.60]) and hypertension (OR = 1.45, 95% CI [1.06 – 1.99]). Conclusion: Patients undergoing RYGB with longer BPL achieved higher weight loss and were more likely to achieve improvement of comorbidities at 5 years. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Optimizing Hospital Performance Evaluation in Total Weight Loss Outcomes After Bariatric Surgery: A Retrospective Analysis to Guide Further Improvement in Dutch Hospitals.
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Bruinsma, Floris F. E., Liem, Ronald S. L., Nienhuijs, Simon W., Greve, Jan Willem M., de Mheen, Perla J. Marang-van, van Acker, G. J. D., Apers, J., Bruin, S. C., de Castro, S. M. M., Damen, S. L., Faneyte, I. F., Greve, J. W. M., van 't Hof, G., Jonker, F. H. W., Klaassen, R. A., Lagae, E. A. G. L., Langenhoff, B. S., Liem, R. S. L., Luijten, A. A. P. M., and Nienhuijs, S. W.
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Introduction: Bariatric surgery aims for optimal patient outcomes, often evaluated through the percentage total weight loss (%TWL). Quality registries employ funnel plots for outcome comparisons between hospitals. However, funnel plots are traditionally used for dichotomous outcomes, requiring %TWL to be dichotomized, potentially limiting feedback quality. This study evaluates whether a funnel plot around the median %TWL has better discriminatory performance than binary funnel plots for achieving at least 20% and 25% TWL. Methods: All hospitals performing bariatric surgery were included from the Dutch Audit for Treatment of Obesity. A funnel plot around the median was constructed using 5-year %TWL data. Hospitals positioned above the 95% control limit were colored green and those below red. The same hospitals were plotted in the binary funnel plots for 20% and 25% TWL and colored according to their performance in the funnel plot around the median. We explored the hospital's procedural mix in relation to %TWL performance as possible explanatory factors. Results: The median-based funnel plot identified four underperforming and four outperforming hospitals, while only one underperforming and no outperforming hospitals were found with the binary funnel plot for 20% TWL. The 25% TWL binary funnel plot identified two underperforming and three outperforming hospitals. The proportion of sleeve gastrectomies performed per hospital may explain part of these results as it was negatively associated with median %TWL (β = − 0.09, 95% confidence interval [− 0.13 to − 0.04]). Conclusion: The funnel plot around the median discriminated better between hospitals with significantly worse and better performance than funnel plots for dichotomized %TWL outcomes. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Feasibility of Postoperative Home Monitoring Using Video Consultation and Vital Sign Monitoring of Bariatric Patients
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Nijland, L. M. G., van Veen, R. N., Ruys, A. T., van Veldhuisen, C. L., Geerdink, T. H., and de Castro, S. M. M.
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- 2020
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7. Oncological Safety and Potential Cost Savings of Routine vs Selective Histopathological Examination After Appendectomy Results of the Multicenter, Prospective, Cross-Sectional FANCY Study
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Bastiaenen, Vivian P., de Jonge, Joske, Corten, Bartholomeus J. G. A., de Savornin Lohman, Elise A. J., Kraima, Anne C., Swank, Hilko A., van Vliet, Jaap L. P., van Acker, Gijs J. D., van Geloven, Anna A. W., in'tHof, Klaas H., Koens, Lianne, de Reuver, Philip R., van Rossem, Charles C., Slooter, Gerrit D., Tanis, Pieter J., Terpstra, Valeska, Dijkgraaf, Marcel G. W., Bemelman, Willem A., Amelung, F. J., Atema, J. J., Bessems, S., Beunders, A. A. M., Bodewes, T. C. F., den Boer, F. C., Boerma, D., Boerma, E. G., van den Boezem, P., Bökkerink, W. J. V., van den Boogaart, D., Boogerd, L. S. F., Bouwman, H., Broos, A., Brueren, L. O., Bruinsma, W. E., Bruns, E. R. C., Castelijns, P. S. S., de Castro, S. M. M., Consten, E. C. J., Crolla, R. M. P. H., Dam, M. J., Dang, Q., Dekker, J. W. T., Deroose, J. P., Devriendt, S., Dijkema, E. J., Dijkstra, N., Driessen, M. L. S., van Duijvendijk, P., Duinhouwer, L. E., van Duyn, E. B., el-Massoudi, Y., Elfrink, A. K. E., Elschot, J. H., van Essen, J. A., Ferenschild, F. T. J., Gans, S. L., Gaznay, C., Geraedts, A. C. M., van Gessel, B. S. H., Giesen, L. J. X., van Gils, N., Gorgec, B., Gorter, R. R., Govaert, K. M., Greuter, G. N., van Grevenstein, W. M. U., Groot, L., Hardy, J. C. A., Heemskerk, J., Heeren, J. F., Heidotting, J., Heikens, J. T., Hosseinzoi, E., van Iersel, J. J., Inberg, B., Jansen, L. J., Jens, A. J. T., Jilesen, A. P. J., Joosten, M., de Jong, L., Keijzers, M., Klicks, R. J., Kloppenberg, F. W. H., Koedam, T. W. A., Koëter, T., Konsten, J. L. M., Koolen, L. J. E. R., Kruyt, Ph. M., Lange, J. F. M., Lavrijssen, B. D. A., de Leede, E. M., Leliefeld, P. H. C., Linnemann, R. J. A., Lo, G. C., van de Loo, M., Lubbert, P. H. W., Holzik, M. F. Lutke, Manusama, E., Masselink, I., Matthée, E. P. C., Matthijsen, R. A., Mearadji, A., Melenhorst, J., Merkus, J. W. S., Michiels, T. D., Moes, D. E., Moossdorff, M., Mulder, E., Nallayici, E. G., Neijenhuis, P. A., Nielsen, K., Nieuwenhuijzen, G. A. P., Nijhuis, J., Okkema, S., Olthof, P. B., van Onkelen, R. S., van Oostendorp, S. E., Plaisier, P. W., Polle, S. W., Reiber, B. M. M., Reichert, F. C. M., van Rest, K. L. C., van Rijn, R., Roozendaal, N. C., de Ruijter, W. M. J., Schat, E., Scheerhoorn, J., Scheijmans, J. C. G., Schimmer, J., Schipper, R. J., Schouten, R., Schreurs, W. H., Schrijver, W. A. M. E., Shapiro, J., Siemons, A., Silvis, R., Simkens, G. A., Smakman, N., Smeets, B. J. J., Sonneveld, D. J. A., van Suijlichem, M., Talsma, A. K., Thoolen, J. M. M., van Tol, R. R., Tournoij, E., Tseng, L. N. L., Tuynman, J. B., van der Velde, K., Veltkamp, S. C., Verbeek, F. P. R., Verdaasdonk, E., Verhaak, T., Verheuvel, N. C., Vermaas, M., Verseveld, M., Vlek, S., Vogels, S., van de Voort, E. M. F., van Vugt, S. T., Wegdam, J. A., Wennekers, M. M., Wiering, B., de Wijkerslooth, E. M. L., Wijkmans, A. A., Wijnhoven, B. P. L., Witjes, C. D. M., Wolfhagen, N., de Zeeuw, S., van Zoonen, G., Surgery, Erasmus MC other, Obstetrics & Gynecology, Department of Strategic Management and Entrepreneurship, Neurology, Rotterdam School of Management, Cardiology, Gastroenterology & Hepatology, Radiology & Nuclear Medicine, Otorhinolaryngology and Head and Neck Surgery, Emergency Medicine, Public Health, Plastic and Reconstructive Surgery and Hand Surgery, Dermatology, Clinical Chemistry, Internal Medicine, Erasmus School of Social and Behavioural Sciences, General Practice, Radiotherapy, Research & Education, Rehabilitation Medicine, Urology, Pathology, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, Hematology laboratory, VU University medical center, CCA - Cancer Treatment and quality of life, and CCA - Imaging and biomarkers
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medicine.medical_specialty ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,All institutes and research themes of the Radboud University Medical Center ,business.industry ,General surgery ,Medicine ,Surgery ,Histopathological examination ,business ,Cost savings - Abstract
Objective: To investigate the oncological safety and potential cost savings of selective histopathological examination after appendectomy. Background: The necessity of routine histopathological examination after appendectomy has been questioned, but prospective studies investigating the safety of a selective policy are lacking. Methods: In this multicenter, prospective, cross-sectional study, inspection and palpation of the (meso)appendix was performed by the surgeon in patients with suspected appendicitis. The surgeon's opinion on additional value of histopathological examination was reported before sending all specimens to the pathologist. Main outcomes were the number of hypothetically missed appendiceal neoplasms with clinical consequences benefiting the patient (upper limit two-sided 95% confidence interval below 3:1000 considered oncologically safe) and potential cost savings after selective histopathological examination. Results: Seven thousand three hundred thirty-nine patients were included. After a selective policy, 4966/7339 (67.7%) specimens would have been refrained from histopathological examination. Appendiceal neoplasms with clinical consequences would have been missed in 22/4966 patients. In 5/22, residual disease was completely resected during additional surgery. Hence, an appendiceal neoplasm with clinical consequences benefiting the patient would have been missed in 1.01:1000 patients (upper limit 95% confidence interval 1.61:1000). In contrast, twice as many patients (10/22) would not have been exposed to potential harm due to re-resections without clear benefit, whereas consequences were neither beneficial nor harmful in the remaining seven. Estimated cost savings established by replacing routine for selective histopathological examination were 725,400 per 10,000 patients. Conclusions: Selective histopathological examination after appendectomy for suspected appendicitis is oncologically safe and will likely result in a reduction of pathologists' workload, less costs, and fewer re-resections without clear benefit.
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- 2023
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8. A Population-Based Cohort Study on Efficacy and Safety of Bariatric Surgery in Young Adults Versus Adults.
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van de Pas, Kelly G. H., Esfandiyari Noushi, Aliyar, Janssen, Loes, Vreugdenhil, Anita C. E., Leclercq, Wouter K. G., van Dielen, François M. H., van Acker, G. J. D., Apers, J. A., Berends, F., de Brauw, L. M., Bruinsma, F. F. E., de Castro, S. M. M., Damen, S. L., Jonker, F., Faneyte, I. F., Greve, J. W. M., van 't Hof, G., Klaassen, R. A., Lagae, E. A. G. L., and Langenhoff, B. S.
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YOUNG adults ,BARIATRIC surgery ,GASTRIC bypass ,COHORT analysis ,GASTRIC banding ,ADULTS ,SLEEVE gastrectomy - Abstract
Purpose: Bariatric surgery is the most effective treatment for severe obesity in adults and has shown promising results in young adults. Lack of insight regarding efficacy and safety outcomes might result in delayed bariatric surgery utilization in young adults. Therefore, this study aimed to assess the efficacy and safety of bariatric surgery in young adults compared to adults. Methods: This is a nationwide population-based cohort study utilizing data from the Dutch Audit Treatment of Obesity (DATO). Young adults (aged 18–25 years) and adults (aged 35–55 years) who underwent primary Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) were included. Primary outcome was percentage total weight loss (%TWL) until five years postoperatively. Results: A total of 2,822 (10.3%) young adults and 24,497 (89.7%) adults were included. The follow-up rates of the young adults were lower up to five years postoperatively (46.2% versus 56.7% three years postoperatively; p < 0.001). Young adults who underwent RYGB showed superior %TWL compared to adults until four years postoperatively (33.0 ± 9.4 versus 31.2 ± 8.7 three years after surgery; p < 0.001). Young adults who underwent SG showed superior %TWL until five years postoperatively (29.9 ± 10.9 versus 26.2 ± 9.7 three years after surgery; p < 0.001). Postoperative complications ≤ 30 days were more prevalent among adults, 5.3% versus 3.5% (p < 0.001). No differences were found in the long term complications. Young adults revealed more improvement of hypertension (93.6% versus 78.9%), dyslipidemia (84.7% versus 69.2%) and musculoskeletal pain (84.6% versus 72.3%). Conclusion: Bariatric surgery appears to be at least as safe and effective in young adults as in adults. Based on these findings the reluctance towards bariatric surgery in the younger age group seems unfounded. [ABSTRACT FROM AUTHOR]
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- 2023
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9. Do Complications Alter Postoperative Weight Loss 1 Year After Primary and Revisional Roux-en-Y Gastric Bypass?
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Coblijn, U. K., de Raaff, C. A. L., Lagarde, S. M., de Castro, S. M. M., Vrouenraets, B. C., and van Wagensveld, B. A.
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- 2016
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10. Weight recurrence after Sleeve Gastrectomy versus Roux-en-Y gastric bypass: a propensity score matched nationwide analysis.
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Akpinar, Erman O., Liem, Ronald S. L., Nienhuijs, Simon W., Greve, Jan Willem M., Marang-van de Mheen, Perla J., the Dutch Audit for Treatment of Obesity Research Group, de Brauw, L. M., de Castro, S. M. M., Damen, S. L., Demirkiran, A., Dunkelgrün, M., Faneyte, I. F., Greve, J. W. M., van 't Hof, G., Janssen, I. M. C., Jutte, E. H., Klaassen, R. A., Lagae, E. A. G. L., Langenhoff, B. S., and Liem, R. S. L.
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PROPENSITY score matching ,SLEEVE gastrectomy ,GASTRIC bypass ,SLEEP apnea syndromes ,LOGISTIC regression analysis ,BARIATRIC surgery - Abstract
Background: Literature remains scarce on patients experiencing weight recurrence after initial adequate weight loss following primary bariatric surgery. Therefore, this study compared the extent of weight recurrence between patients who received a Sleeve Gastrectomy (SG) versus Roux-en-Y gastric bypass (RYGB) after adequate weight loss at 1-year follow-up. Methods: All patients undergoing primary RYGB or SG between 2015 and 2018 were selected from the Dutch Audit for Treatment of Obesity. Inclusion criteria were achieving ≥ 20% total weight loss (TWL) at 1-year and having at least one subsequent follow-up visit. The primary outcome was ≥ 10% weight recurrence (WR) at the last recorded follow-up between 2 and 5 years, after ≥ 20% TWL at 1-year follow-up. Secondary outcomes included remission of comorbidities at last recorded follow-up. A propensity score matched logistic regression analysis was used to estimate the difference between RYGB and SG. Results: A total of 19.762 patients were included, 14.982 RYGB and 4.780 SG patients. After matching 4.693 patients from each group, patients undergoing SG had a higher likelihood on WR up to 5-year follow-up compared with RYGB [OR 2.07, 95% CI (1.89–2.27), p < 0.01] and less often remission of type 2 diabetes [OR 0.69, 95% CI (0.56–0.86), p < 0.01], hypertension (HTN) [OR 0.75, 95% CI (0.65–0.87), p < 0.01], dyslipidemia [OR 0.44, 95% CI (0.36–0.54), p < 0.01], gastroesophageal reflux [OR 0.25 95% CI (0.18–0.34), p < 0.01], and obstructive sleep apnea syndrome (OSAS) [OR 0.66, 95% CI (0.54–0.8), p < 0.01]. In subgroup analyses, patients who experienced WR after SG but maintained ≥ 20%TWL from starting weight, more often achieved HTN (44.7% vs 29.4%), dyslipidemia (38.3% vs 19.3%), and OSAS (54% vs 20.3%) remission compared with patients not maintaining ≥ 20%TWL. No such differences in comorbidity remission were found within RYGB patients. Conclusion: Patients undergoing SG are more likely to experience weight recurrence, and less likely to achieve comorbidity remission than patients undergoing RYGB. [ABSTRACT FROM AUTHOR]
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- 2023
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11. Evaluation of CPAP adherence in bariatric patients diagnosed with obstructive sleep apnea: outcomes of a multicenter cohort study
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van Veldhuisen, S. L., primary, van Boxel, M. F., additional, Wiezer, M. J., additional, van Veen, R. N., additional, de Castro, S. M. M., additional, Swank, D. J., additional, Demirkiran, A., additional, Boerma, E. G., additional, Greve, J. W. M., additional, van Dielen, F. M. H., additional, Kuppens, K., additional, and Hazebroek, E. J., additional
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- 2022
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12. Prospective nationwide outcome audit of surgery for suspected acute appendicitis
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van Rossem, C. C., Bolmers, M. D. M., Schreinemacher, M. H. F., van Geloven, A. A. W., Bemelman, W. A., van Acker, G. J. D., Akkermans, B., Akkersdijk, G. J. M., Algie, G. D., Allema, J. H., Andeweg, C. S., Appeldorn, N., van Baal, J. G., den Bakker, C. M., Bartels, S. A. L., van den Berg, C., Boekestijn, B., den Boer, F. C., Boerma, D., van den Boom, A. L., Boute, M. C., Bouwense, S. A. W., Bransen, J., van Brussel, F. A., Busch, O. R. C., de Castro, S. M. M., Cense, H. A., Croese, C., van Dalen, T., Dawson, I., van Dessel, E., Dettmers, R., Dhar, N., Dohmen, F. Y. M., van Dongen, K. W., van Duijvendijk, P., Dulfer, R. R., Dwars, B. J., Eerenberg, J. P., van der Elst, M., van den Ende, E., Fassaert, L. M. M., Fikkers, J. T., Foppen, J. W., Furnee, E. J. B., Garssen, F. P., Gerhards, M. F., van Goor, H., Gorter, R. R., de Graaf, J. S., Graat, L. J., Groote, J., van der Ham, A. C., Hamming, J. F., Hamminga, J. T. H., van der Harst, E., Heemskerk, J., Heij, H. A., Heijne, A., Heikens, J. T., Heineman, E., Hertogs, R., van Heurn, E., van den Hil, L. C. L., Hoofwijk, A. G. M., Hulsker, C. C. C., Hunen, D. R. M., Ibelings, M. S., Klaase, J. M., Klicks, R., Knaapen, L., Kortekaas, R. T. J., Kruyt, F., Kwant, S., Lases, S. S., Lettinga, T., Loupatty, A., Matthijsen, R. A., Minnee, R. C., Mirck, B., Mitalas, L., Moes, D., Moorman, A. M., Nieuwenhuijs, V. B., Nieuwenhuijzen, G. A. P., Nijk, P. D., Omloo, J. M. T., Ottenhof, A. G., Palamba, H. W., van der Peet, D. L., Pereboom, I. T. A., Plaisier, P. W., van der Ploeg, A. P. T., Raber, M. H., Reijnen, M. M. P. J., Rijna, H., Rosman, C., Roumen, R. M. H., Schmitz, R. F., van der Velden, Schouten A. P., Schreurs, W. H., Sigterman, T. A., Smeets, H. J., Sonneveld, D. J. A., Sosef, M. N., Spoor, S. F., Stassen, L. P. S., van Steensel, L., Stortelder, E., Straatman, J., van Susante, H. J., de Hoog, Suykerbuyk D. E. N. M., van Scheltinga, Terwisscha C., Toorenvliet, B. R., Verbeek, B. M., Verbeek, P. C. M., Verseveld, M., Volders, J. H., Vriens, M. R., Vriens, P. W. H. E., Vrouenraets, B. C., van de Wall, B. J. M., Wegdam, J. A., Westerduin, E., Wever, J. J., Wijffels, N. A. T., Wijnhoven, B. P. L., Winkel, T. A., van der Zee, D. C., Zeillemaker, A. M., and Zietse, C.
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- 2016
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13. Hospital Variation in Preference for a Specific Bariatric Procedure and the Association with Weight Loss Performance: a Nationwide Analysis.
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Akpinar, Erman O., Liem, Ronald S. L., Nienhuijs, Simon W., Greve, Jan Willem M., Marang-van de Mheen, Perla J., on behalf of the Dutch Audit for Treatment of Obesity Research Group, de Brauw, L. M., de Castro, S. M. M., Damen, S. L., Demirkiran, A., Dunkelgrün, M., Faneyte, I. F., van 't Hof, G., Janssen, I. M. C., Jutte, E. H., Klaassen, R. A., Lagae, E. A. G. L., Langenhoff, B. S., Luijten, A. A. P. M., and Schouten, R.
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WEIGHT loss ,GASTRIC bypass ,SLEEVE gastrectomy ,BARIATRIC surgery ,HOSPITALS - Abstract
Purpose: Hospitals performing a certain bariatric procedure in high volumes may have better outcomes. However, they could also have worse outcomes for some patients who are better off receiving another procedure. This study evaluates the effect of hospital preference for a specific type of bariatric procedure on their overall weight loss results. Methods: All hospitals performing bariatric surgery were included from the nationwide Dutch Audit for Treatment of Obesity. For each hospital, the expected (E) numbers of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one-anastomosis gastric bypass (OAGB) were calculated given their patient-mix. These were compared with the observed (O) numbers as the O/E ratio in a funnel plot. The 95% control intervals were used to identify outlier hospitals performing a certain procedure significantly more often than expected given their patient-mix (defined as hospital preference for that procedure). Similarly, funnel plots were created for the outcome of patients achieving ≥ 25% total weight loss (TWL) after 2 years, which was linked to each hospital's preference. Results: A total of 34,558 patients were included, with 23,154 patients completing a 2-year follow-up, of whom 79.6% achieved ≥ 25%TWL. Nine hospitals had a preference for RYGB (range O/E ratio [1.09–1.53]), with 1 having significantly more patients achieving ≥ 25%TWL (O/E ratio [1.06]). Of 6 hospitals with a preference for SG (range O/E ratio [1.10–2.71]), one hospital had significantly fewer patients achieving ≥ 25%TWL (O/E ratio [0.90]), and from two hospitals with a preference for OAGB (range O/E ratio [4.0–6.0]), one had significantly more patients achieving ≥ 25%TWL (O/E ratio [1.07]). One hospital had no preference for any procedure but did have significantly more patients achieving ≥ 25%TWL (O/E ratio [1.10]). Conclusion: Hospital preference is not consistently associated with better overall weight loss results. This suggests that even though experience with a procedure may be slightly less in hospitals not having a preference, it is still sufficient to achieve similar weight loss outcomes when surgery is provided in centralized high-volume bariatric institutions. [ABSTRACT FROM AUTHOR]
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- 2022
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14. Evaluation of the Appendicitis Inflammatory Response Score for Patients with Acute Appendicitis
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de Castro, S. M. M., Ünlü, Ç., Steller, E. Ph., van Wagensveld, B. A., and Vrouenraets, B. C.
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- 2012
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15. Evaluation of POSSUM for Patients Undergoing Pancreatoduodenectomy
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de Castro, S. M. M., Houwert, J. T., Lagarde, S. M., Reitsma, J. B., Busch, O. R. C., van Gulik, T. M., Obertop, H., and Gouma, D. J.
- Published
- 2009
- Full Text
- View/download PDF
16. Preoperative Biliary Drainage in Patients with Obstructive Jaundice: History and Current Status
- Author
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van der Gaag, N. A., Kloek, J. J., de Castro, S. M. M., Busch, O. R. C., van Gulik, T. M., and Gouma, D. J.
- Published
- 2009
- Full Text
- View/download PDF
17. Management of Solid-pseudopapillary Neoplasms of the Pancreas: a Comparison with Standard Pancreatic Neoplasms
- Author
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de Castro, S. M. M., Singhal, D., Aronson, D. C., Busch, O. R. C., van Gulik, T. M., Obertop, H., and Gouma, D. J.
- Published
- 2007
- Full Text
- View/download PDF
18. Response to: “Letter to the Editor: Trocar Site Hernia Prevention in Laparoscopic Bariatric Surgery”
- Author
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Coblijn, Usha K. and de Castro, S. M. M.
- Published
- 2016
- Full Text
- View/download PDF
19. Diagnostic Laparoscopy for Primary and Secondary Liver Malignancies: Impact of Improved Imaging and Changed Criteria for Resection
- Author
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de Castro, S. M. M., Tilleman, E. H. B. M., Busch, O. R. C., van Delden, O. M., Laméris, J. S., van Gulik, T. M., Obertop, H., and Gouma, D. J.
- Published
- 2004
- Full Text
- View/download PDF
20. Henoch-Schönlein Disease Localized in the Appendix
- Author
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de Castro, S. M. M., Joosse, P., Ünlü, Ç., and Steller, E. Ph.
- Published
- 2013
- Full Text
- View/download PDF
21. Pain in the leg after jogging
- Author
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de Castro, S M M, Joosse, P, Ünlü, Ç, and Steller, E P H
- Published
- 2009
- Full Text
- View/download PDF
22. Validation of a nomogram for predicting survival after resection for adenocarcinoma of the pancreas
- Author
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de Castro, S. M. M., Biere, S. S. A. Y., Lagarde, S. M., Busch, O. R. C., van Gulik, T. M., and Gouma, D. J.
- Published
- 2009
- Full Text
- View/download PDF
23. Pancreas-preserving total duodenectomy versus standard pancreatoduodenectomy for patients with familial adenomatous polyposis and polyps in the duodenum
- Author
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de Castro, S. M. M., van Eijck, C. H. J., Rutten, J. P., Dejong, C. H., van Goor, H., Busch, O. R. C., and Gouma, D. J.
- Published
- 2008
24. Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer
- Author
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Lagarde, S. M., Maris, A. K. D., de Castro, S. M. M., Busch, O. R. C., Obertop, H., and van Lanschot, J. J. B.
- Published
- 2007
25. Prognostic nomogram for patients undergoing oesophagectomy for adenocarcinoma of the oesophagus or gastro-oesophageal junction
- Author
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Lagarde, S. M., Reitsma, J. B., de Castro, S. M. M., ten Kate, F. J. W., Busch, O. R. C., and van Lanschot, J. J. B.
- Published
- 2007
26. Incidence and management of pancreatic leakage after pancreatoduodenectomy
- Author
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de Castro, S. M. M., Busch, O. R. C., van Gulik, T. M., Obertop, H., and Gouma, D. J.
- Published
- 2005
27. The Influence of Body Contouring Surgery on Weight Control and Comorbidities in Patients After Bariatric Surgery
- Author
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de Vries, C. E. E., primary, Kalff, M. C., additional, van Praag, E. M., additional, Florisson, J. M. G., additional, Ritt, M. J. P. F., additional, van Veen, R. N., additional, and de Castro, S. M. M., additional
- Published
- 2019
- Full Text
- View/download PDF
28. The Influence of Body Contouring Surgery on Weight Control and Comorbidities in Patients After Bariatric Surgery.
- Author
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de Vries, C. E. E., Kalff, M. C., van Praag, E. M., Florisson, J. M. G., Ritt, M. J. P. F., van Veen, R. N., and de Castro, S. M. M.
- Subjects
BARIATRIC surgery ,COMORBIDITY ,WEIGHT loss ,GASTRIC bypass ,SURGERY ,LONGITUDINAL method - Abstract
Introduction: A considerable number of patients experience some long-term weight regain after bariatric surgery. Body contouring surgery (BCS) is thought to strengthen post-bariatric surgery patients in their weight control and maintenance of achieved improvements in comorbidities. Objectives: To examine the impact of BCS on long-term weight control and comorbidities after bariatric surgery. Methods: We performed a retrospective study in a prospective database. All patients who underwent primary Roux-en-Y gastric bypass (RYGB) and presented for preoperative consultation of BCS in the same hospital were included in the study. Linear and logistic mixed-effect model analyses were used to evaluate the longitudinal relationships between patients who were accepted or rejected for BCS and their weight loss outcomes or changes in comorbidities. Results: Of the 1150 patients who underwent primary RYGB between January 2010 and December 2014, 258 patients (22.4%) presented for preoperative consultation of BCS. Of these patients, 126 patients eventually underwent BCS (48.8%). Patients who were accepted for BCS demonstrated significant better ∆body mass index (BMI) on average over time (− 1.31 kg/m
2 /year, 95% confidence interval (CI) −2.52 − −0.10, p = 0.034) and percent total weight loss (%TWL) was significantly different at 36 months (5.79, 95%CI 1.22 – 10.37, p = 0.013) and 48 months (6.78, 95%CI 0.93 – 12.63, p = 0.023) after body contouring consultation. Patients who were accepted or rejected did not differ significantly in the maintenance of achieved improvements in comorbidities. Conclusion: BCS could not be associated with the maintenance of achieved improvements in comorbidities after bariatric surgery, whereas it could be associated with improved weight loss maintenance at 36 and 48 months after body contouring consultation. This association should be further explored in a large longitudinal study. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
29. Erratum to: Evaluation of the Appendicitis Inflammatory Response Score for Patients with Acute Appendicitis
- Author
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de Castro, S. M. M., Ünlü, Ç., Steller, E. Ph., van Wagensveld, B. A., and Vrouenraets, B. C.
- Published
- 2012
- Full Text
- View/download PDF
30. Body mass index and complications following major gastrointestinal surgery: A prospective, international cohort study and meta-analysis
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Blanco-Colino, R., Lee, S., Kamarajah, S. K., Vasko, P., Kuiper, S. Z., Farina, V., Chapman, S. J., Drake, T. M., Gavagna, L., Pasquali, S., Pata, F., Pellino, G., de la Rosa-Estadella, M., Stellingwerf, M. E., Stijns, R. C. H., Borrellas, A., Golding, D., Ngaage, M., Van Tol, R. R., de Groof, J., de Wilt, H., Bemelman, W. A., Mcnamee, L., Espin-Basany, E., Emre Baki, B., Gecim, I. E., Can Tatar, O., Bach, S., Bhangu, A., Bresges, K., Burke, J., Claireaux, H. A., Fearnhead, N., Fitzgerald, J. E., Gallagher, S., Glasbey, J. C., Gundogan, B., Harrison, E. M., Hernon, J., Khatri, C., Kong, C. Y., Lyons, A., Mohan, M., Morton, D., Pinkney, T. D., Arezzo, A., Foppa, C., Morino, M., Rubbini, M., Selvaggi, F., Sensi, B., Sica, G., Orhalmi, J., Naccari, P., Sgro, A., Burger, B. H. C. M., Fares, D. A., Spijkerman, R., van Elst, T. R., Wiersema, R., Stassen, L. P. S., Rodriguez Garcia, R., Ozkan, B. B., Tavuz, A. I., Demirci, Z. S., Baki, B. E., Choi, P. J., O'Sullivan, H., Salman, M., Simioni, A., Colombo, F., Turati, L., Cazzola, F. E., Gallo, G., Perrotta, G., Papandrea, M., Naccari, P. M., Menduni, N., Rossi, E., Chetta, N., Romeo, F., Giordano, F., Randisi, B., Curletti, G., Kuiper, J., Costa, A., Marcos Rodrigo, A., Sanchez, A., Varo Munoz, A., Martinez Rios, C. E., Aliseda-Jover, D., Fernandez Nieto, D., Alvarez Reyes, I., Dominguez Rodriguez, L. M., Hernandez Ros, M. I., Esteban Sinovas, O., Bartrina Soler, P., Villarejo Campos, P., Laguna Roman, S., Fontanet-Soler, S., Raurich-Leandro, J., Dominguez-Prieto, V., Segura-Sampedro, J. J., Alconchel-Gago, F., Salazar-Garcia, C., Gezen, A. E., Sahin, A., Atasoy, H., Yuksek, B., Arslan, E., Ozmen, B. B., Sen, A. Y., Erol, H. I., Ucar, E., Aktas, M. K., Yurdaor, S. S., Mermer, S., Seyhan, U., Tosun, V., Gunaydin, Y., Ekinci, Z. B., Yazkan, Z., Choi, J., Yeoh, T. S. L., Jones, C. S., Venturini, S., Saat, M. I., Loo, J., Pike, G., Davies, S. C., Kabariti, R., Olivier, J., Hurny, M., Zebrak, R., Machacova, A., Schulzova, M., Smolak, P., Siroka, M., Palyzova, H., Jaros, J., Dusek, T., Simackova, B., Bartos, M., Sotona, O., Pos, M., Karasek, D., Higgins, P., Hacking, S., Arora, E., Coughlan, G., Palanivail, N., Quill, S., Zhang, A. A., Malak, M., Maan, D. S., Cheema, J., Goh, A. W. J., Shamsul Badrin, A. K., Guinness, F., Howard James, N., Neary, A., Sebaoui, S., Gilroy, D., Petrov, G., Craven, K., Macdonald, A., Redmond, A., Brennan, D., Roche, D., O'Dwyer, M., Collins, P., Edwards, S., Doyle, J., Tiedt, L., Arthurs, B., O'Byrne, L., Kiely, A., Glynn, M., Sproule, L., Heaney, A., Li Hi Shing, S., Goh, W., Al-Nasser, Z., Al-Nasser, A., Teh, J. W., De Boni, D., Goldin, E., Ciccioli, E., Vendramin, E., Marchese, N., Bruno, M., Vinci, A., Harder, G., Morandi, V., Magnoli, M., Suppa, A., Palmieri, A., Martorana, M., Sette, M., Balagna, P., Cruciani, C., Corte, M., Ciano, P., Bagaglini, G., Montuori, M., Di Benedetto, L., Arcudi, C., Pezzuto, R., Saraceno, F., Milana, F., Franceschilli, M., Rizzi, A., Sampietro, G., Rampulla, V., Bianco, F., Boschetti, M. E., Ghignone, F., Bianchini, S., Esposto, R., Riva, L., Riva, M., Cannavo, M., Arrigo, A., Giavarini, L., Colombo, E. M., Trompetto, M., Clerico, G., Catalano, M., Dosa, T., El Mabruk, M., Barone, V., Pallara, E., Pasqualoni, M., Caudullo, G., Mastandrea Bonaviri, G. N., Muro, M., Pistola, I., Verardi, L., Ferrara, D., Gerardi, S., Remore, L. M., Belia, F., Del Coco, F., Larotonda, C., Botrugno, E. M., Cammarota, A., Di Girolami, L., Laterza, V., Laurino, A., Paolo, G., Santocchi, P., Puccioni, C., Truma, A., Giardino, F. R., Giuffrida, A., Ripa, M., Cautiero, R., Patturelli, M., Capozzolo, A., Selvaggi, L., Facchiano, A., Milazzo, L. F., Papazachariou, S. K., Pattapola, V., Anania, G., Feo, C., Bellinato, M., Priani, P., Zigiotto, D., Troia, A., Vable, T., Piran, G., Targa, S., Pulpito, S., Tagariello, F., Fasano, A., Anconelli, D., Castiglione, F., Tognolo, L., Lopez, G., Campion, A., Tarantino, M., Sacco, R., Sammarco, G., Palmisano, S., Giacca, M., Rocco, I., Bellio, G., Favero, A., Raimondi, P., Pantalone, M. R., De Nardi, P., Notarnicola, M., Picciariello, A., Licari, L., Parinisi, Z., Fazzotta, S., Ciciliot, M., Reggiani, L., Mariani, F., Aonzo, P., Checcacci, P., Montanelli, P., Guerra, F., Skalamera, I., Staderini, F., Grandi, S., Nelli, T., de Boer, D. V., van der Pool, A. E. M., Janssen, T. L., El-Atmani, S., van Verschuer, V. M. T., Poelman, M., Dronkers, W. J., van Steensel, L., Toorenvliet, B. R., Duinhouwer, L. E., Vermaas, M., Ter Bruggen, F. F. J. A., Hogendoorn, W., van der Harst, E., van Rijckevorsel, V. A. J. I. M., Bayoumy, A. B., Lap, C. R., Gooszen, J. A. H., Abdulrahman, N., de Roy van Zuidewijn, D., de Groof, E. J., Zijlmans, J. L., van Dalen, A. S. H. M., Bos, K., Musters, G. D., Looijen, R. C., Fliers, J. M., Oostendorp, S. E., Mosterd, C. M., Blonk, L., Jurgens, J., Ribbink, M. E., Boom, M. S., Boersma, A. M., Hidding, E., Schmidt, P. A., Mensink, G., Graus, S. A., Gastel, M. D. A., Veenker, C. G. H., Van Heumen, T. M., Slieker, F. J. B., Sedee, W. J. A., Lowensteyn, Y. N., Amelung, F. J., de Guerre, L. E. V. M., Nota, C. L. M. A., Van Dijck, W. P. M., van Wijnbergen, J. W. M., Pronk, A., Kip, M., van der Zee, C., Heiloo, S., Muller, S., Verboeket, B., Oudman, T. S., Zope, S., Gilissen, V., Gommers, J., Cremers, D., Van der Lubbe, M., Smet, M., Ter Weele, K., de Bruin, M., Geerlings, M., Ter Horst, L., Kerimova, N., Pesser, N., Heesakkers, H., de Mees, T., de Gooyer, J. M., Willems, L., Gawria, L., Bonouvrie, D., Harms, J., Eggen, Y., Hengeveld, E., Smeets, H. J., Hoffman, R. P. C., Detmers Blom, F. P. N., Van Bruggen, D., Steup, W. H., Gooiker, G. A., Willems, Y. R., van der Hoeven, A. C., Vallve-Bernal, M., Perez-Gandara, B., Perez, J. L., Caballero Rodriguez, E., Perez Febles, M., Protti Ruiz, G. P., Hidalgo Pujol, M., Alberti Delgado, P., Gil Barrionuevo, E., Anabitarte, O., Caballero, L., Poyato Nunez, F. J., Prado Perez, R., de la Portilla de Juan, F., Fulgencio Barbarin, J., Elorza Echaniz, G., Mitxelena Elosegi, L., Delgado, A. T., Marti Gelonch, L., Gonzalez Arribas, M., De Serra Tejada, I., Alberdi San Roman, I., de Andres Olabarria, U., Fernandez-Domper, L., Perez Costoya, C., Perez Arias, H., Fa Binefa, M., Becerra Nieves, M., Escalona Canal, M. G., Aldrey, I., Vazquez-Gonzalez, I., Falcon Cazas, A., Amarelo Garcia, M., Gonzalez Ruiz, A. A., Garcia Garrido, M., Simon Frapolli, V., Martinez Diaz, J. M., De la Torre Conde, C., Rodrigues Silva, K., Hernandez Kakauridze, S., Lopez Garcia, M. C., Flores Funes, D., Gomez-Lopez de San Roman, C., San Martin Bragado, M., Tejero Pintor, F. J., Pando Ruiz, B., Sanchez Estebanez, E., Roquet Puignero, E., Pla Sero, S., Vela Polanco, F. F., Mirallas Vinas, O., Caro Gonzalez, M. P., Bertelli Puche, J. L., Gonzalez-Martinez, A., Sanchez Cambronero, M., Garcia Torres, A., Dominguez Jimenez, M., de Jesus Rodriguez Perdomo, M., Echazarreta-Gallego, E., Sanchez-Blasco, L., Del Mar Lopez-Cuevas, M., Latras-Cortes, I., Lopez-Vendrell, L., Diaz Padillo, A., Mestres Petit, N., Cruz Reyes, J. A., Fernandez, C., Posada, M., Moratilla Lapena, L., Martin Morales, E., Mate-Mate, P., Garcia Cruz, G., Gorini, L., Rubio-Perez, I., Soldevila-Verdeguer, C., Jimenez-Vinas, C., Luehrman, A., Sena-Ruiz, F., Garcia-Perez, J. M., Plomer-Sanchez, M., Pujol-Cano, N., Jimenez-Segovia, M., Diaz-Jover, P., Pineno-Flores, C., Ambrona-Zafra, D., Gonzalez-Argente, X. F., Jimenez-Morillas, P., Lopez-Marmol, R., Duran-Martinez, M., Gonzalez-Crespo, A., Checa Guillen, M., Valderrama Perez, A., Claramonte Bellmunt, O., Marti Fernandez, R. M., Kasap, S., Soylemez, Z. O. B. B., Bolat, A. B., Aydar, S. E. Y. I., Birgin, B. Z., Coskun, O., Cakir, S. G., Belibagli, Z. O., Herken, M., Erdem, S., Kayacan, S., Kelesoglu, Y., Moran, D., Atalay, H., Kucukdiler, E., Demirci, A., Buyukkasap, C., Kuzey, A., Emral, C., Dogan, H., Cok, H., Durmaz, H., Asma, A., Ergul, B., Kaya, A., Bilicen, G., Gunay, M., Senturk, E., Baskoy, L., Besisik, H. M., Topalan, K., Piraliyev, E., Danalioglu, A. N., Ilbak, A., Yigman, S., Kara, C., Guzel, M., Inci, E. T., Onsal, U., Erel, T., Cetin, S. K., Yekenkurul, E., Kasar, P., Saglam, Z. A., Gursoy, F., Cetinkaya, M., Aktekin, H., Bober, D. N., Mugurtay, Y. S., Koksal, G., Celik, S., Bektur, G., Yildirim, R., Ankarali, T., Guven, H., Yuksel, A., Semiz, A., Cise, S., Tomas, K., Ulusahin, M., Akbulut, F., Tulum, H., Bodur, S., Isler, V. C., Pektas, A. M., Mutlu, D., Mericliler, M., Tansoker, I., Polat, Z. P., Seyrek, N., Beyatli, S., Toto, O. F., Cakaloglu, H. C., Sapci, I., Akpunarli, B., Adiyaman, C., Kobal, B. B., Gok, Z., Benli, S., Turpan, M., Kocapinar, S., Parimli, H., Acar, S., Eger, M., Yilmaz, I., Cengiz, U., Yoruk, I., Mutlu, B., Ulkucu, A., Arukan, C., Kara, B., Gokce, K., Calisgan, B., Demirci, K., Elkatroushi, T., Ayaz, B., Uzun, B., Sivrikaya, T., Goksoy, B., Eroz, E., Celik, B., Canbay Torun, B., Ekin, B., Senay, B. B., Temiz, C., Yilmaz, M., Yasar, C., Cakir, E., Subasi, A., Celik, K., Aksoy, K., Karabulut, E., Altintas, O., Bali, A. N., Ciftci, E., Babaoglu, H., Aljbour, A., Aljbour, I., Akcaoglu, T., Kakil, E., Taskin, O., Taskin, R. B., Topal, U., Huzmeli, E., Caliskan, T., Unal, A. G., Yurekli, A. M., Sari, V., Tutam, D. N., Celen, D., Posteki, G., Demirtas, B., Yildiz, S., Kilic, E., Yalcin, Y., Kurt, A., Gozubuyuk, Y., Huseynova, S., Cinar, S., Calar, S. N., Kurklu, O., Binbuga, M., Ceylan, C., Yavuz, G., Alim, Y. E., Yildirim, N., Yilmaz, S., Onar, D., Aray, E., Ozsipahi, A. C., Koc, G. E., Yetiskin, E., Kocer, M. D., Ozgencil, B., Bahcecioglu, B., Hacioglu, A. D., Bilici, O., Cin, S., Uzunoglu, E. C., Cumen, E. C., Aslan, L., Erozgur, B., Yildiz, S. S., Zengin, T., Kullac, S., Mizan, S. R., Baykan, B., Kopac, O., Karabacak, U., Aytekin, A., Deliktas, T. S., Buyukkarabacak, Y., Uzun, O., Karahan, B., Turkmen, M., Akdogan, A., Uctepe, F., Bandirmali, O., Erdogan, P., Demir, F., Bozkurt, G. K., Yilmaz, T., Sheikh, I. M. I., Orhan, K., Balci, B., Keyif, M. F., Bilgin, S., Cantimer, E., Yaman, S., Akkaya, E., Atesavci, S. N., Arslan, U., Asik, M., Koksal, S., Murtaza, M. I., Mustafa, S., Oun, H., Sam, Z. H., Brogan, A., Zaidi, R., Quinn, K., Taylor, F., Pang, G., Heath, H., Smart, N. J., Home, J., Mauro, D., Noone, T. M., Fenn, J., Sinha, A., Lowe, R., Hutchings, I., Longstaff, L., Smith, A. G., Edwards, J. A., Alcocer, B. P., Oakley, T., Thomas-Davies, M., Hourston, G. J. M., Kankam, H. K. N., Ramana, A., Baker, C., Endo, Y., Wong, C., Anderson, R. G. J., Badran, A., Ali, A., Myers, L., Tippins, F., Stanley, S., Sandison, L., Schofield, E., Delf, J., Rees, S., Anyan-Brown, J., Long, K., Archer, M., Anakwenze, V., Goel, S., Sharma Khatiwada, A., Khan, S., Leafe, O., Lee, J., Embury-Young, Y., Edwards, L., Hazenberg, P., Agrawal, M., Guerero, D., Britton, F., Rejayee, M., Mahesh, S., Khaing, P. H., Baldwin, A., Iyer, S., Gaskell, P., Adlan, A., Cuckow, L., Barmayehvar, B., Rob, T., Ciurleo, C., Mural-Krishnan, S., Jong, N., Carlson, S., Abdelgalil, R., Goble, M., Doshi, A., Ogunleye, O., Marsh, L., Bagley, J., Poacher, A., Cantelo, J., Wylie, J., Govil, S., Hill, F., Beaver, D., Urquhart, A., Rakhimov, I., Raina, V., Clifford, T., Iorga, R., Cartwright, E., Harris, A. J., Shurovi, B., Wadanamby, S., Brown, E., Bradley, C., Ahmad, A., Jeyabraba, S., Hardaman, B., Truss, A., Mohamed, U. S., Kerin, M. J., Reynolds, J., Ridgway, P., Pietrabissa, A., Foschi, D., Sgroi, G., Rosati, G., Benevento, A., Coco, Claudio, Persiani, R., Vasquez, G., Messina, F., De Manzini, N., Innocenti, P., Rosati, R., Altomare, D. F., Sartori, A., Salamone, G., Galleano, R., Cianchi, F., Wijnhoven, B. P. L., van de Ven, A. W. H., de Vos Tot Nederveen Cappel, R. J., de Castro, S. M. M., Meijerink, W. J. H. J., Mulder, I. M., Acherman, Y. I. Z., van Leeuwen, B. L., Schasfoort, R. A., Kloppenberg, F. W. H., Wiezer, R., Consten, E. C. J., Van Grevenstein, W. M. U., Schiphorst, A., Wijffels, N., Uittenbogaart, M., Klinkert, M., Koppe, M., de Hingh, I., Konsten, J., Polat, F., Berends, F., Langenhoff, B., Zimmerman, D., van Engelenburg, T., Vries, J. J. M., Baeten, C. I. M., Bastiaansen, A. J. N. M., van Geloven, A., Khan, I., Girones, J., Barrera Gomez, M., Sanz Ortega, G., Duran Munoz-Cruzado, V. M., Ruiz Montesinos, I., Enriquez-Navascues, J. M., Portugal Porras, V., Baixauli, J., Garcia Florez, L. J., Alonso Goncalves, S., Parajo, A., Sanchez-Guillen, L., Lujan Mompean, J. A., Soria Aledo, V., Arenal, J. J., Blanco Antona, F., Badia, J. M., Roura, J., Garcia Garcia, J., Elia-Guedea, M., Millan, M., Vinas-Salas, J., Garcia-Olmo, D., Prieto-Nieto, M. I., Medina-Fernandez, F. J., Romero-Simo, M., Frasson, M., Espi Macias, A., Tirnaksiz, M. B., Leventoglu, S., Kara, E., Tasci, Y., Pehlivan, M., Guner, A., Ozben, V., Agalar, C., Albayrak, D., Ertekin, C., Oncel, M., Sakman, G., Guler, S. A., Firat, O., Akkucuk, S., Ozbalci, G. S., Sozuer, E. M., Sengul, N., Schizas, A., Horgan, P. G., Singh, B., Harikrishnan, A., Stechman, M., Hayat, J., Coyne, P., Wilson, T., Arun, C., Manvydas, V., Moroni, P., Lo Secco, G., Argenti, F., Romano, F., Calcagno, P., Steccanella, F., Cisternino, G., Bottini, C., Realis Luc, A., Apicella, M., Candilio, G., Gubbiotti, F., De Luca, E., Casagranda, B., Decorato, A., Aquilino, F., Badii, B., Rahmee, C. N. 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C., Kabariti, R., Olivier, J., Hurny, M., Zebrak, R., Machacova, A., Schulzova, M., Smolak, P., Siroka, M., Palyzova, H., Jaros, J., Dusek, T., Simackova, B., Bartos, M., Sotona, O., Pos, M., Karasek, D., Higgins, P., Hacking, S., Arora, E., Coughlan, G., Palanivail, N., Quill, S., Zhang, A. A., Malak, M., Maan, D. S., Cheema, J., Goh, A. W. J., Shamsul Badrin, A. K., Guinness, F., Howard James, N., Neary, A., Sebaoui, S., Gilroy, D., Petrov, G., Craven, K., Macdonald, A., Redmond, A., Brennan, D., Roche, D., O'Dwyer, M., Collins, P., Edwards, S., Doyle, J., Tiedt, L., Arthurs, B., O'Byrne, L., Kiely, A., Glynn, M., Sproule, L., Heaney, A., Li Hi Shing, S., Goh, W., Al-Nasser, Z., Al-Nasser, A., Teh, J. W., De Boni, D., Goldin, E., Ciccioli, E., Vendramin, E., Marchese, N., Bruno, M., Vinci, A., Harder, G., Morandi, V., Magnoli, M., Suppa, A., Palmieri, A., Martorana, M., Sette, M., Balagna, P., Cruciani, C., Corte, M., Ciano, P., Bagaglini, G., Montuori, M., Di Benedetto, L., Arcudi, C., Pezzuto, R., Saraceno, F., Milana, F., Franceschilli, M., Rizzi, A., Sampietro, G., Rampulla, V., Bianco, F., Boschetti, M. E., Ghignone, F., Bianchini, S., Esposto, R., Riva, L., Riva, M., Cannavo, M., Arrigo, A., Giavarini, L., Colombo, E. M., Trompetto, M., Clerico, G., Catalano, M., Dosa, T., El Mabruk, M., Barone, V., Pallara, E., Pasqualoni, M., Caudullo, G., Mastandrea Bonaviri, G. N., Muro, M., Pistola, I., Verardi, L., Ferrara, D., Gerardi, S., Remore, L. M., Belia, F., Del Coco, F., Larotonda, C., Botrugno, E. M., Cammarota, A., Di Girolami, L., Laterza, V., Laurino, A., Paolo, G., Santocchi, P., Puccioni, C., Truma, A., Giardino, F. R., Giuffrida, A., Ripa, M., Cautiero, R., Patturelli, M., Capozzolo, A., Selvaggi, L., Facchiano, A., Milazzo, L. F., Papazachariou, S. K., Pattapola, V., Anania, G., Feo, C., Bellinato, M., Priani, P., Zigiotto, D., Troia, A., Vable, T., Piran, G., Targa, S., Pulpito, S., Tagariello, F., Fasano, A., Anconelli, D., Castiglione, F., Tognolo, L., Lopez, G., Campion, A., Tarantino, M., Sacco, R., Sammarco, G., Palmisano, S., Giacca, M., Rocco, I., Bellio, G., Favero, A., Raimondi, P., Pantalone, M. R., De Nardi, P., Notarnicola, M., Picciariello, A., Licari, L., Parinisi, Z., Fazzotta, S., Ciciliot, M., Reggiani, L., Mariani, F., Aonzo, P., Checcacci, P., Montanelli, P., Guerra, F., Skalamera, I., Staderini, F., Grandi, S., Nelli, T., de Boer, D. V., van der Pool, A. E. M., Janssen, T. L., El-Atmani, S., van Verschuer, V. M. T., Poelman, M., Dronkers, W. J., van Steensel, L., Toorenvliet, B. R., Duinhouwer, L. E., Vermaas, M., Ter Bruggen, F. F. J. 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M., Willems, L., Gawria, L., Bonouvrie, D., Harms, J., Eggen, Y., Hengeveld, E., Smeets, H. J., Hoffman, R. P. C., Detmers Blom, F. P. N., Van Bruggen, D., Steup, W. H., Gooiker, G. A., Willems, Y. R., van der Hoeven, A. C., Vallve-Bernal, M., Perez-Gandara, B., Perez, J. L., Caballero Rodriguez, E., Perez Febles, M., Protti Ruiz, G. P., Hidalgo Pujol, M., Alberti Delgado, P., Gil Barrionuevo, E., Anabitarte, O., Caballero, L., Poyato Nunez, F. J., Prado Perez, R., de la Portilla de Juan, F., Fulgencio Barbarin, J., Elorza Echaniz, G., Mitxelena Elosegi, L., Delgado, A. T., Marti Gelonch, L., Gonzalez Arribas, M., De Serra Tejada, I., Alberdi San Roman, I., de Andres Olabarria, U., Fernandez-Domper, L., Perez Costoya, C., Perez Arias, H., Fa Binefa, M., Becerra Nieves, M., Escalona Canal, M. G., Aldrey, I., Vazquez-Gonzalez, I., Falcon Cazas, A., Amarelo Garcia, M., Gonzalez Ruiz, A. A., Garcia Garrido, M., Simon Frapolli, V., Martinez Diaz, J. M., De la Torre Conde, C., Rodrigues Silva, K., Hernandez Kakauridze, S., Lopez Garcia, M. C., Flores Funes, D., Gomez-Lopez de San Roman, C., San Martin Bragado, M., Tejero Pintor, F. J., Pando Ruiz, B., Sanchez Estebanez, E., Roquet Puignero, E., Pla Sero, S., Vela Polanco, F. F., Mirallas Vinas, O., Caro Gonzalez, M. P., Bertelli Puche, J. L., Gonzalez-Martinez, A., Sanchez Cambronero, M., Garcia Torres, A., Dominguez Jimenez, M., de Jesus Rodriguez Perdomo, M., Echazarreta-Gallego, E., Sanchez-Blasco, L., Del Mar Lopez-Cuevas, M., Latras-Cortes, I., Lopez-Vendrell, L., Diaz Padillo, A., Mestres Petit, N., Cruz Reyes, J. A., Fernandez, C., Posada, M., Moratilla Lapena, L., Martin Morales, E., Mate-Mate, P., Garcia Cruz, G., Gorini, L., Rubio-Perez, I., Soldevila-Verdeguer, C., Jimenez-Vinas, C., Luehrman, A., Sena-Ruiz, F., Garcia-Perez, J. M., Plomer-Sanchez, M., Pujol-Cano, N., Jimenez-Segovia, M., Diaz-Jover, P., Pineno-Flores, C., Ambrona-Zafra, D., Gonzalez-Argente, X. F., Jimenez-Morillas, P., Lopez-Marmol, R., Duran-Martinez, M., Gonzalez-Crespo, A., Checa Guillen, M., Valderrama Perez, A., Claramonte Bellmunt, O., Marti Fernandez, R. M., Kasap, S., Soylemez, Z. O. B. B., Bolat, A. B., Aydar, S. E. Y. I., Birgin, B. Z., Coskun, O., Cakir, S. G., Belibagli, Z. O., Herken, M., Erdem, S., Kayacan, S., Kelesoglu, Y., Moran, D., Atalay, H., Kucukdiler, E., Demirci, A., Buyukkasap, C., Kuzey, A., Emral, C., Dogan, H., Cok, H., Durmaz, H., Asma, A., Ergul, B., Kaya, A., Bilicen, G., Gunay, M., Senturk, E., Baskoy, L., Besisik, H. M., Topalan, K., Piraliyev, E., Danalioglu, A. N., Ilbak, A., Yigman, S., Kara, C., Guzel, M., Inci, E. T., Onsal, U., Erel, T., Cetin, S. K., Yekenkurul, E., Kasar, P., Saglam, Z. A., Gursoy, F., Cetinkaya, M., Aktekin, H., Bober, D. N., Mugurtay, Y. S., Koksal, G., Celik, S., Bektur, G., Yildirim, R., Ankarali, T., Guven, H., Yuksel, A., Semiz, A., Cise, S., Tomas, K., Ulusahin, M., Akbulut, F., Tulum, H., Bodur, S., Isler, V. C., Pektas, A. M., Mutlu, D., Mericliler, M., Tansoker, I., Polat, Z. P., Seyrek, N., Beyatli, S., Toto, O. F., Cakaloglu, H. C., Sapci, I., Akpunarli, B., Adiyaman, C., Kobal, B. B., Gok, Z., Benli, S., Turpan, M., Kocapinar, S., Parimli, H., Acar, S., Eger, M., Yilmaz, I., Cengiz, U., Yoruk, I., Mutlu, B., Ulkucu, A., Arukan, C., Kara, B., Gokce, K., Calisgan, B., Demirci, K., Elkatroushi, T., Ayaz, B., Uzun, B., Sivrikaya, T., Goksoy, B., Eroz, E., Celik, B., Canbay Torun, B., Ekin, B., Senay, B. B., Temiz, C., Yilmaz, M., Yasar, C., Cakir, E., Subasi, A., Celik, K., Aksoy, K., Karabulut, E., Altintas, O., Bali, A. N., Ciftci, E., Babaoglu, H., Aljbour, A., Aljbour, I., Akcaoglu, T., Kakil, E., Taskin, O., Taskin, R. B., Topal, U., Huzmeli, E., Caliskan, T., Unal, A. G., Yurekli, A. M., Sari, V., Tutam, D. N., Celen, D., Posteki, G., Demirtas, B., Yildiz, S., Kilic, E., Yalcin, Y., Kurt, A., Gozubuyuk, Y., Huseynova, S., Cinar, S., Calar, S. N., Kurklu, O., Binbuga, M., Ceylan, C., Yavuz, G., Alim, Y. E., Yildirim, N., Yilmaz, S., Onar, D., Aray, E., Ozsipahi, A. C., Koc, G. E., Yetiskin, E., Kocer, M. D., Ozgencil, B., Bahcecioglu, B., Hacioglu, A. D., Bilici, O., Cin, S., Uzunoglu, E. C., Cumen, E. C., Aslan, L., Erozgur, B., Yildiz, S. S., Zengin, T., Kullac, S., Mizan, S. R., Baykan, B., Kopac, O., Karabacak, U., Aytekin, A., Deliktas, T. S., Buyukkarabacak, Y., Uzun, O., Karahan, B., Turkmen, M., Akdogan, A., Uctepe, F., Bandirmali, O., Erdogan, P., Demir, F., Bozkurt, G. K., Yilmaz, T., Sheikh, I. M. I., Orhan, K., Balci, B., Keyif, M. F., Bilgin, S., Cantimer, E., Yaman, S., Akkaya, E., Atesavci, S. N., Arslan, U., Asik, M., Koksal, S., Murtaza, M. I., Mustafa, S., Oun, H., Sam, Z. H., Brogan, A., Zaidi, R., Quinn, K., Taylor, F., Pang, G., Heath, H., Smart, N. J., Home, J., Mauro, D., Noone, T. M., Fenn, J., Sinha, A., Lowe, R., Hutchings, I., Longstaff, L., Smith, A. G., Edwards, J. A., Alcocer, B. P., Oakley, T., Thomas-Davies, M., Hourston, G. J. M., Kankam, H. K. N., Ramana, A., Baker, C., Endo, Y., Wong, C., Anderson, R. G. J., Badran, A., Ali, A., Myers, L., Tippins, F., Stanley, S., Sandison, L., Schofield, E., Delf, J., Rees, S., Anyan-Brown, J., Long, K., Archer, M., Anakwenze, V., Goel, S., Sharma Khatiwada, A., Khan, S., Leafe, O., Lee, J., Embury-Young, Y., Edwards, L., Hazenberg, P., Agrawal, M., Guerero, D., Britton, F., Rejayee, M., Mahesh, S., Khaing, P. H., Baldwin, A., Iyer, S., Gaskell, P., Adlan, A., Cuckow, L., Barmayehvar, B., Rob, T., Ciurleo, C., Mural-Krishnan, S., Jong, N., Carlson, S., Abdelgalil, R., Goble, M., Doshi, A., Ogunleye, O., Marsh, L., Bagley, J., Poacher, A., Cantelo, J., Wylie, J., Govil, S., Hill, F., Beaver, D., Urquhart, A., Rakhimov, I., Raina, V., Clifford, T., Iorga, R., Cartwright, E., Harris, A. J., Shurovi, B., Wadanamby, S., Brown, E., Bradley, C., Ahmad, A., Jeyabraba, S., Hardaman, B., Truss, A., Mohamed, U. S., Kerin, M. J., Reynolds, J., Ridgway, P., Pietrabissa, A., Foschi, D., Sgroi, G., Rosati, G., Benevento, A., Coco, Claudio, Persiani, R., Vasquez, G., Messina, F., De Manzini, N., Innocenti, P., Rosati, R., Altomare, D. F., Sartori, A., Salamone, G., Galleano, R., Cianchi, F., Wijnhoven, B. P. L., van de Ven, A. W. H., de Vos Tot Nederveen Cappel, R. J., de Castro, S. M. M., Meijerink, W. J. H. J., Mulder, I. M., Acherman, Y. I. Z., van Leeuwen, B. L., Schasfoort, R. A., Kloppenberg, F. W. H., Wiezer, R., Consten, E. C. J., Van Grevenstein, W. M. U., Schiphorst, A., Wijffels, N., Uittenbogaart, M., Klinkert, M., Koppe, M., de Hingh, I., Konsten, J., Polat, F., Berends, F., Langenhoff, B., Zimmerman, D., van Engelenburg, T., Vries, J. J. M., Baeten, C. I. M., Bastiaansen, A. J. N. M., van Geloven, A., Khan, I., Girones, J., Barrera Gomez, M., Sanz Ortega, G., Duran Munoz-Cruzado, V. M., Ruiz Montesinos, I., Enriquez-Navascues, J. M., Portugal Porras, V., Baixauli, J., Garcia Florez, L. J., Alonso Goncalves, S., Parajo, A., Sanchez-Guillen, L., Lujan Mompean, J. A., Soria Aledo, V., Arenal, J. J., Blanco Antona, F., Badia, J. M., Roura, J., Garcia Garcia, J., Elia-Guedea, M., Millan, M., Vinas-Salas, J., Garcia-Olmo, D., Prieto-Nieto, M. I., Medina-Fernandez, F. J., Romero-Simo, M., Frasson, M., Espi Macias, A., Tirnaksiz, M. B., Leventoglu, S., Kara, E., Tasci, Y., Pehlivan, M., Guner, A., Ozben, V., Agalar, C., Albayrak, D., Ertekin, C., Oncel, M., Sakman, G., Guler, S. A., Firat, O., Akkucuk, S., Ozbalci, G. S., Sozuer, E. M., Sengul, N., Schizas, A., Horgan, P. G., Singh, B., Harikrishnan, A., Stechman, M., Hayat, J., Coyne, P., Wilson, T., Arun, C., Manvydas, V., Moroni, P., Lo Secco, G., Argenti, F., Romano, F., Calcagno, P., Steccanella, F., Cisternino, G., Bottini, C., Realis Luc, A., Apicella, M., Candilio, G., Gubbiotti, F., De Luca, E., Casagranda, B., Decorato, A., Aquilino, F., Badii, B., Rahmee, C. N. S., Kleine, E., Yauw, S., de Zeeuw, S., Aarts, E., Teixeira da Silva, M., Brueren, L., Bokkerink, G., Schok, T., Graafland, M., Gonzalez de Chaves, P. E., Jimenez-Gomez, L. M., Garcia Galocha, J. L., Palos Campos, M. C., Jimenez Escovar, F., Hernandez-Lizoain, J. L., Monzonis Hernandez, X., Dominguez Sanchez, J. M., Vives-Rodriguez, E., Abrisqueta Carrion, J., Beltran de Heredia, J., Padilla Valverde, D., Alcazar Montero, J. A., Cordoba-Diaz de Laspra, E., Franco Chacon, M., Muriel, P., Pastor-Riquelme, P., Peinado Iribar, B., Alonso Hernandez, N., Costa-Navarro, D., Martinez Chillaron, E., Secilmis, E., Bamac, E., Koc, F., Kayaci Durak, M., Bayram, S., Ekrem, M., Uzun, S., Gok, A. F. K., Gorguner, F., Yildiz, T., Dalci, K., Kilinc, C., Koc, M., Yuksek, M. A., Ersoy, T., Celik, E., Parmar, E., Abuhussein, N., Metcalf, P., Atif, M., Heywood, E., Mayes, J. W., Kelly, M., Mitchell, H., Antoniou, I., Dean, R., Davies, N., Trecarten, S., Henderson, I., Holmes, C., Shuttleworth, R. H., Jindal, A., Hughes, F., Gouda, P., Fleck, R., Hanrahan, M., Karunakaran, P., Chen, J. H., Sykes, M. C., Sethi, R. K., Suresh, S., Patel, P., Patel, M., Varma, R. K., Mushtaq, J., Bolton, W., Khan, T., Morley, R., Favero, N., Adams, R., Thirumal, V., Kennedy, E. D., Ong, K. K., Tan, Y. H., Gabriel, J., Bakhsh, A., Low, J. Y. L., Yener, A., Paraoan, V., Preece, R., Tilston, T. W., Cumber, E., Dean, S., Ross, T., Mccance, E., Amin, H., Satterthwaite, L., Clement, K. D., Gratton, R., Mills, E. D., Chiu, S. M., Hung, G., Rafiq, N. M., Hayes, J. D. B., Robertson, K. L., Dynes, K., Huang, H. C., Assadullah, S., Duncumb, J. W., Moon, R. D. C., Poo, S. X., Mehta, J. K., Joshi, K. R., Callan, R., Norris, J. M., Chilvers, N. J., Keevil, H., Jull, P., Mallick, S., Elf, D., Carr, L., Player, C., Barton, E. C., Martin, A. L., Ratu, S. G., Roberts, E. J., Phan, P. N., Dyal, A. R., Rogers, J. E., Henson, A. D., Reid, N. B., Burke, D., Culleton, G., Lynne, S., Mansoor, S., Brennan, C., Blessed, R., Holloway, C., Hill, A., Goldsmith, T., Mackin, S., Kim, S., Woin, E., Brent, G., Coffin, J., Ziff, O., Momoh, Z., Debenham, R., Ahmed, M., Yong, C. S., Wan, J. C., Copley, H. C., Raut, P., Chaudhry, F. I., Nixon, G., Dorman, C., Tan, R., Kanabar, S., Canning, N., Dolaghan, M., Bell, N., Mcmenamin, M., Chhabra, A., Duke, K., Turner, L., Patel, T., Chew, L. S., Mirza, M., Lunawat, S., Oremule, B., Ward, N., Khan, M., Tan, E. T., Maclennan, D., Mcgregor, R. J., Chisholm, E. G., Griffin, E. J., Bell, L., Hughes, B. A., Davies, J., Haq, H., Ahmed, H., Ungcharoen, N., Whacha, C., Thethi, R., Markham, R. M., Lee, A. H. Y., Batt, E., Bullock, N. P., Francescon, C. T., Davies, J. E., Shafiq, N. M., Zhao, J., Vivekanantham, S., Barai, I., Allen, J. L. Y., Marshall, D. C., Mcintyre, C. J., Wilson, H. C. P., Ashton, A. 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F., Lim, K., Ho, S., Crewdson, J. A., Singagireson, S., Kalra, N., Koumpa, F., Jhala, H., Soon, W. C., Karia, M., Rasiah, M. G., Xylas, D., Gilbert, H., Sundar-Singh, M., Wills, J., Akhtar, S., Patel, S., Hu, L., Brathwaite-Shirley, C., Nayee, H., Amin, O., Rangan, T., Turner, E. J. H., Mccrann, C., Shepherd, R., Patel, N., Prest-Smith, J., Auyoung, E., Murtaza, A., Coates, A., Prys-Jones, O., King, M., Gaffney, S., Dewdney, C. J., Nehikhare, I., Lavery, J., Bassett, J., Davies, K., Ahmad, K., Collins, A., Acres, M., Egerton, C., Cheng, K., Chen, X., Chan, N., Sheldon, A., Empey, J., Ingram, E., Malik, A., Johnstone, M., Goodier, R., Shah, J. P., Giles, J. E., Sanders, J. A., Mclure, S. W., Pal, S., Rangedara, A., Baker, A. N., Asbjoernsen, C. A., Girling, C., Gray, L., Gauntlett, L., Joyner, C., Qureshi, S., Mogan, Y. P., Ng, J. C. K., Kumar, A. N., Park, J. H., Tan, D., Choo, K. P., Raman, K. P., Buakuma, P., Xiao, C., Govinden, S., Thompson, O. D., Charalambos, M. A., Karsan, R. 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B., Beecroft, S., Sarvanandan, T., Weston, C., Bassam, N., Rabinthiran, S., Hayat, U., Ng, L., Varma, D., Sukkari, M., Mian, A., Omar, A., Kim, J. W., Sellathurai, J., Mahmood, J., O'Connell, C., Bose, R., Heneghan, H., Lalor, P., Matheson, J., Doherty, C., Cullen, C., Cooper, D., Angelov, S., Drislane, C., Smith, A. C. D., Kreibich, A., Palkhi, E., Durr, A., Lotfallah, A., Gold, D., Mckean, E., Dhanji, A., Anilkumar, A., Thacoor, A., Siddiqui, Z. H., Lim, S., Piquet, A., Anderson, S. M., Mccormack, D. R., Gulati, J., Ibrahim, A., Murray, S. E., Walsh, S. L., Mcgrath, A., Ziprin, P., Chua, E. Y., Lou, C. N., Bloomer, J., Paine, H. R., Osei-Kuffour, D., White, C. J., Szczap, A., Gokani, S., Patel, K., Malys, M. K., Reed, A., Torlot, G. E., Cumber, E. M., Charania, A., Ahmad, S., Varma, N., Cheema, H., Austreng, L., Petra, H., Chaudhary, M., Zegeye, M. I., Cheung, F., Coffey, D., Heer, R. S., Singh, S., Seager, E., Cumming, S., Suresh, R. S., Verma, S., Ptacek, I. B., Gwozdz, A. M., Yang, T., Khetarpal, A. A., Shumon, S., Fung, T. M. P., Leung, W., Kwang, P., Chew, L., Loke, W., Curran, A., Chan, C., Mcgarrigle, C., Mohan, K., Cullen, S., Wong, E., Toale, C., Collins, D., Keane, N., Traynor, B. P., Shanahan, D., Yan, A., Jafree, D. J., Topham, C., Mitrasinovic, S., Omara, S., Bingham, G., Lykoudis, P. M., Miranda, B. H., Whitehurst, K., Kumaran, G., Devabalan, Y., Aziz, H., Shoa, M., Dindyal, S., Yates, J. A., Bernstein, I., Rattan, G., Coulson, R., Stezaker, S., Isaac, A., Salem, M., Mcbride, A., Mcfarlane, H., Yow, L., Macdonald, J., Bartlett, R. D., Turaga, S., White, U., Liew, W., Yim, N., Ang, A., Simpson, A., Mcauley, D., Craig, E., Murphy, L., Shepherd, P., Kee, J. Y., Abdulmajid, A., Chung, A., Warwick, H. L., Livesey, A., Holton, P., Theodoreson, M. D., Jenkin, S. L., Turner, J., Entwisle, J. H., Marchal, S. T., O'Connor, S., Blege, H. K., Aithie, J. M., Sabine, L. M., Stewart, G. E., Jackson, S., Kishore, A., Lankage, C. M., Acquaah, F., Joyce, H. L., Mckevitt, K. L., Coffey, C. J., Fawaz, A. S., Dolbec, K. S., O'Sullivan, D. A., Geraghty, J. M., Lim, E., Bolton, L., Fitzpatrick, D., Robinson, C., Ramtoola, T., Collinson, S., Grundy, L., Mcenhill, P. M., Harbhajan Singh, G. S., Loughran, D., Golding, D. M., Keeling, R. E., Williams, R. P., Whitham, R. D. J., Yoganathan, S., Nachiappan, R., Egan, R. J., Owasil, R., Kwan, M. L., He, A., Goh, R. W., Bhome, R., Wilson, H., Teoh, P. J., Raji, K., Jayakody, N., Matthams, J., Chong, J., Luk, C. Y., Greig, R. J., Trail, M., Charalambous, G., Rocke, A. S., Gardiner, N., Bulley, F., Warren, N., Brennan, E., Fergurson, P., Wilson, R., Whittingham, H., Brown, E. J., Khanijau, R., Gandhi, K., Morris, S., Boulton, A. J., Chandan, N., Barthorpe, A. E., Maamari, R., Sandhu, S., Mccann, M., Higgs, L., Balian, V., Reeder, C., Diaper, C., Sale, T., Ali, H., Archer, C. H., Clarke, A. K., Heskin, J., Hurst, P. C., Farmer, J. D., O'Flynn, L. D., Doan, L., Shuker, B. A., Stott, G. D., Vithanage, N. A., Hoban, K. A., Nesargikar, P. N., Kennedy, H. R., Grossart, C. M., Tan, E. S. M., Roy, C. S. D., Sim, P., Leslie, K. E., Sim, D., Abul, M. H., Cody, N., Tay, A. Y., Woon, E., Sng, S., Mah, J., Robson, J., Shakweh, E., Wing, V. C., Mills, H., Li, M. M., Barrow, T. R., Balaji, S., Jordan, H. E. M., Phillips, C., Naveed, H., Hirani, S., Tai, A., Ratnakumaran, R., Sahathevan, A., Shafi, A. M. A., Seedat, M., Weaver, R., Batho, A., Punj, R., Selvachandran, H., Bhatt, N., Botchey, S., Khonat, Z., Brennan, K., Morrison, C. J., Devlin, E., Linton, A., Galloway, E., Mcgarvie, S., Ramsay, N., Mcrobbie, H. D., Whewell, H., Dean, W., Nelaj, S., Eragat, M., Mishra, A., Kane, T., Zuhair, M., Wells, M., Wilkinson, D., Woodcock, N., Sun, E., Aziz, N., Abd Ghaffar, M. K., Bath, M. F., Nepogodiev, D., and Coco C. (ORCID:0000-0002-4713-7093)
- Abstract
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a metaanalysis of all available prospective data. Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien–Dindo Grades III–V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results. Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery formalignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49–2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46–0.75, P < 0.001) compared to normal weight patients. Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease.
- Published
- 2018
31. Multicentre randomized controlled trial comparing ferric(III)carboxymaltose infusion with oral iron supplementation in the treatment of preoperative anaemia in colorectal cancer patients
- Author
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Borstlap, W. A. A., primary, Buskens, C. J., additional, Tytgat, K. M. A. J., additional, Tuynman, J. B., additional, Consten, E. C. J., additional, Tolboom, R. C., additional, Heuff, G., additional, van Geloven, N., additional, van Wagensveld, B. A., additional, C.A. Wientjes, C. A., additional, Gerhards, M. F., additional, de Castro, S. M. M., additional, Jansen, J., additional, van der Ven, A. W. H., additional, van der Zaag, E., additional, Omloo, J. M., additional, van Westreenen, H. L., additional, Winter, D. C., additional, Kennelly, R. P., additional, Dijkgraaf, M. G. W., additional, Tanis, P. J., additional, and Bemelman, W. A., additional
- Published
- 2015
- Full Text
- View/download PDF
32. Preoperatieve galwegdrainage voor pancreaskoptumoren: meer complicaties*
- Author
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van der Gaag, N. A., Rauws, E. A. J., van Eijck, C. H. J., Bruno, M. J., van der Harst, E., Kubben, F. J. G. M., Gerritsen, J. J. G. M., Greve, J. W., Gerhards, M. F., de Hingh, I. H. J. T., Klinkenbijl, J. H., Yung Nio, C., de Castro, S. M. M., Busch, O. R. C., van Gulik, T. M., Bosssuyt, P. M. M., Gouma, D. J., Other departments, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, Gastroenterology and Hepatology, and Surgery
- Published
- 2010
33. Images in emergency medicine. Pain in the leg after jogging
- Author
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de Castro, S. M. M., Joosse, P., Unlü, C., Steller, E. P. H., Other Research, and Surgery
- Published
- 2009
34. Centralisatie van pancreasoperaties: een systematische review en evaluatie in Nederland
- Author
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van Heek, N. T., Kuhlmann, K. F. D., Scholten, R. J. P. M., de Castro, S. M. M., Busch, O. R. C., van Gulik, T. M., Obertop, H., Gouma, D. J., Amsterdam Public Health, Epidemiology and Data Science, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, and Surgery
- Abstract
OBJECTIVE: To analyse the volume-outcome effect of pancreatic surgery by means of a systematic review, and to determine the effect of the ongoing plea for centralisation of pylorus-preserving pancreaticoduodenectomy in the Netherlands. DESIGN: Systematic review and retrospective evaluation. METHOD: A systematic search for studies comparing hospital mortality rates after pancreatic resection in high- and low-volume hospitals was conducted. The studies were independently assessed regarding design, inclusion criteria, threshold value for high and low volume and primary hospital mortality outcome. Data were obtained from the Dutch nation-wide registry on the mortality outcome of pancreaticoduodenectomy in 1994-2003. Hospitals were divided into 4 categories based on the number of pancreaticoduodenectomies performed. The effect of the ongoing plea for centralisation was analysed. RESULTS: Twelve observational studies comprising a total of 19,688 patients were included. Because the studies were too heterogeneous to allow a meta-analysis, a qualitative analysis was performed. The relative risk of dying in a high-volume hospital compared with a low-volume hospital was between 0.07 and 0.76 and was inversely proportional to the arbitrarily defined volume cut-off values. Various analyses conducted over a to-year period in the Netherlands reported mortality rates of 14-17% in hospitals that performed fewer than 5 pancreaticoduodenectomies per year, compared with rates of 0.0-3.50 degrees h in hospitals that performed more than 24 pancreaticoduodenectomies per year. The percentage of patients undergoing surgery in hospitals with a volume less than ro pancreaticoduodenectomies per year was 57% in 2000-2003 (454/792), compared with 65% (280/428) in 1994-1995. CONCLUSION: This systematic review provided evidence of an inverse relationship between hospital volume and mortality after pancreaticoduodenectomy and confirmed the value of centralisation of this procedure in high-volume hospitals. The 10-year-long plea of the Dutch surgical community for quality assessment and, if necessary, centralisation has not resulted in a reduction in mortality rates after pancreatic resection or a change in referral patterns in The Netherlands
- Published
- 2006
35. Duodenum, jejunum en ileum
- Author
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de Castro, S. M. M., Bartelsman, J. F. W. M., Gouma, D. J., Smeenk, H. G., Schep, N. W. L., Grevenstein, W. M. U., Gastroenterology and Hepatology, and Surgery
- Published
- 2005
36. Surgical palliation in pancreatic cancer
- Author
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Kuhlmann, K. F. D., de Castro, S. M. M., Gouma, D. J., Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, and Surgery
- Abstract
The prognosis of patients with pancreatic carcinoma is poor. At the time of diagnosis, approximately 80% of patients are found to have an unresectable tumour, because of local spread or metastatic disease. Therefore, most patients will undergo palliative treatment, which is aimed at the improvement of the quality of life and the prevention of symptoms. The most important symptoms which are associated with advanced pancreatic cancer are pain, obstructive jaundice and gastric outlet obstruction. Controversy remains on the question whether these symptoms should be treated surgically or non-surgically. This review describes the best evidence (if possible randomised controlled trials) in recent literature on the palliation of most important symptoms and focuses on surgical palliative treatment options
- Published
- 2004
37. Surgical treatment of pancreatic adenocarcinoma: actual survival and prognostic factors in 343 patients
- Author
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Kuhlmann, K. F. D., de Castro, S. M. M., Wesseling, J. G., ten Kate, F. J. W., Offerhaus, G. J. A., Busch, O. R. C., van Gulik, T. M., Obertop, H., Gouma, D. J., Pathology, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, and Surgery
- Abstract
Survival data of patients with pancreatic carcinoma are often overestimated because of incomplete follow-up. Therefore, the aim of this study was to approach complete follow-up and to analyse survival and prognostic factors of patients who underwent surgical treatment for pancreatic adenocarcinoma. Between 1992 and 2002, 343 patients underwent surgical treatment for pancreatic adenocarcinoma. One hundred and sixty patients underwent a resection with a curative intention and 183 patients underwent bypass surgery for palliation. Follow-up was complete for 93% of patients. Median survival after resection and bypass was 17.0 and 7.5 months, and 5-year survival was 8% and 0, respectively. In multivariate analysis, tumour-positive lymph nodes, non-radical surgery, poor tumour differentiation, and tumour size were independent prognostic factors for survival after resection. For patients treated with bypass surgery, metastatic disease and tumour size independently predicted survival. In conclusion, actual survival of patients with pancreatic adenocarcinoma is disappointing compared with the actuarial survival rates reported in the literature. The independent prognostic factors for survival of patients who underwent surgical treatment for pancreatic adenocarcinoma are tumour-related. (C) 2003 Elsevier Ltd. All rights reserved
- Published
- 2004
38. Henoch-Schönlein Disease Localized in the Appendix
- Author
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de Castro, S. M. M., primary, Joosse, P., additional, Ünlü, Ç., additional, and Steller, E. Ph., additional
- Published
- 2012
- Full Text
- View/download PDF
39. Preoperative Biliary Drainage in Patients with Obstructive Jaundice: History and Current Status
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van der Gaag, N. A., primary, Kloek, J. J., additional, de Castro, S. M. M., additional, Busch, O. R. C., additional, van Gulik, T. M., additional, and Gouma, D. J., additional
- Published
- 2008
- Full Text
- View/download PDF
40. Validation of the O-POSSUM-score in patients with oesophageal cancer
- Author
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Lagarde, S. M., primary, Maris, A. K., additional, de Castro, S. M. M., additional, Busch, O. R. C., additional, Obertop, H., additional, and van Lanschot, J .J. B., additional
- Published
- 2006
- Full Text
- View/download PDF
41. Evaluation of a selective management strategy of patients with primary cystic neoplasms of the pancreas.
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de Castro, S M M, Houwert, J T, van der Gaag, N A, Busch, O R C, van Gulik, T M, and Gouma, D J
- Published
- 2011
42. POSSUM Predicts Survival in Patients with Unresectable Pancreatic Cancer.
- Author
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De Castro, S. M. M., Houwert, J. T., Lagard, S. M., Busch, O. R. C., Van Gulik, T. M., and Gouma, D. J.
- Subjects
- *
PANCREATIC cancer , *PANCREATIC surgery , *CANCER-related mortality , *GASTRIC bypass , *MULTIVARIATE analysis , *PALLIATIVE treatment , *SURGICAL complications - Abstract
Background: The aim of this study was to evaluate the physiological and operative severity score for the enumeration of mortality and morbidity (POSSUM) for patients with unresectable pancreatic cancer and to analyze whether POSSUM can predict the long-term outcome in these patients. Such a scoring system could be useful to aid in the decision between surgical and endoscopic palliation. Methods: Between January 1993 and December 2004, 241 patients were found to have unresectable pancreatic cancer during exploratory laparotomy and underwent a double bypass procedure consisting of a gastrojejunostomy and a hepaticojejunostomy. Results: Overall, 64 of 240 patients (27%) had one or more complications after bypass surgery and 4 patients (2%) died. POSSUM predicted morbidity in 114 patients (47%). The observed:predicted (O:P) ratio for morbidity was 0.56 and the model had a significant lack of fit (p < 0.001) using a goodness-of-fit analysis. The overall median survival was 7 months. The POSSUM scoring system was, however, an independent predictor of survival in multivariate analysis. Conclusions: Overall, POSSUM overpredicted morbidity but was an independent predictor of survival. Copyright © 2009 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
43. A Systematic Review of the Efficacy of Gum Chewing for the Amelioration of Postoperative Ileus.
- Author
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de Castro, S. M. M., van den Esschert, J. W., van Heek, N. T., Dalhuisen, S., Koelemay, M. J. W., Busch, O. R. C., and Gouma, D. J.
- Subjects
- *
BOWEL obstructions , *GINGIVA , *COLECTOMY , *COLON cancer , *RECTAL cancer , *RANDOMIZED controlled trials - Abstract
Background: Recent trials have shown promising results for the efficacy of gum chewing for the amelioration of postoperative ileus. This finding could have a major clinical impact since gum chewing is relatively harmless and cheap while postoperative ileus has a significant impact on healthcare. Methods: Systematic review and meta-analysis of randomized controlled trials comparing the efficacy of gum chewing after colorectal surgery to a standard control for the amelioration of postoperative ileus, expressed as time to flatus, time to defecation and overall hospital stay. Results: Five randomized controlled trials with a total number of 158 patients were found. The studies were homogeneous and a meta-analysis was performed. The pooled weighted mean difference (WMD) of time to flatus was significantly shorter for the gum-chewing group (20 h with a 95% confidence interval (CI) of 13–27). The pooled WMD of time to defecation was significantly shorter (29 h, 95% CI of 19–39). There was a non-significant trend towards a shorter postoperative hospital stay (1.3 days shorter, 95% CI of 3.2 days shorter to 0.6 days longer). Conclusion: This meta-analysis shows a favorable effect of gum chewing on time to flatus and defecation but no significant effect on the hospital stay. Copyright © 2008 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
- View/download PDF
44. Erratum to: Multicentre randomized controlled trial comparing ferric(III) carboxymaltose infusion with oral iron supplementation in the treatment of preoperative anaemia in colorectal cancer patients.
- Author
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Borstlap, W. A. A., Buskens, C. J., Tytgat, K. M. A. J., Tuynman, J. B., Consten, E. C. J., Tolboom, R. C., Heuff, G., van Geloven, A. A. W., van Wagensveld, B. A., Wientjes, C. A. C. A., Gerhards, M. F., de Castro, S. M. M., Jansen, J., van der Ven, A. W. H., van der Zaag, E., Omloo, J. M., van Westreenen, H. L., Winter, D. C., Kennelly, R. P., and Dijkgraaf, M. G. W.
- Subjects
SPELLING errors ,PERSONAL names - Abstract
A correction to the article "Multicentre randomized controlled trial comparing ferric(III) carboxymaltose infusion with oral iron supplementation in the treatment of preoperative anaemia in colorectal cancer patients," by W. A. A. Borstlap and colleagues in the 2015 issue is presented.
- Published
- 2015
- Full Text
- View/download PDF
45. Complications and predictors associated with moderate to severe obstructive sleep apnoea in bariatric surgery: Evaluation of routine obstructive sleep apnoea screening.
- Author
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Nijland LMG, van Veldhuisen SL, van Veen RN, Hazebroek EJ, Bonjer HJ, and de Castro SMM
- Subjects
- Humans, Male, Female, Obesity complications, Polysomnography, Body Mass Index, Bariatric Surgery adverse effects, Sleep Apnea, Obstructive complications, Sleep Apnea, Obstructive diagnosis, Sleep Apnea, Obstructive epidemiology, Obesity, Morbid complications, Obesity, Morbid surgery
- Abstract
Purpose: Obstructive sleep apnoea (OSA) is a breathing disorder resulting in blockage of airflow and hypo-oxygenation. The incidence of OSA in patients with class 2 or 3 obesity (Body Mass index, BMI >35) is 60-70%. Unfortunately, most bariatric patients are unaware they suffer from OSA. Untreated OSA can lead to perioperative cardiopulmonary complications. The aim of this study was to identify predictors associated with moderate to severe OSA and asses the incidence of OSA-related complications in a large cohort of patients who underwent OSA-screening and treatment if indicated before bariatric surgery., Methods: All consecutive patients who underwent primary bariatric surgery between September 2013 and September 2019 were included. Univariable and multivariable logistic regression analysis was performed to identify potential predictors for moderate to severe OSA using sleep studies., Results: A total of 2872 patients who underwent bariatric surgery were included for analysis. Overall, OSA was identified in 62.5% of all patients and moderate to severe OSA (AHI ≥15) in 28.6%. Independent predictors for moderate to severe OSA were male gender (p < 0.001), age (p < 0.001), preoperative BMI (p < 0.001), preoperative waist circumference (p < 0.001), hypertension (p < 0.001), and dyslipidaemia (p = 0.046). The incidence of OSA-related complications was low (0.8%) and not significantly different among the different OSA severity classes., Conclusion: This is the largest study to assess OSA presence and OSA-related complications in patients undergoing bariatric surgery. The incidence of potential OSA-related complications was low (0.8%). We believe focus could be shifted towards more cost-efficient strategies where OSA screening is omitted such as perioperative continuous monitoring., Competing Interests: Declaration of competing interest All authors declare to have no conflict of interest., (Copyright © 2023 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2023
- Full Text
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46. Validation of a Scoring System to Distinguish Uncomplicated From Complicated Appendicitis.
- Author
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Geerdink TH, Augustinus S, Atema JJ, Jensch S, Vrouenraets BC, and de Castro SMM
- Subjects
- Adult, Appendicitis diagnostic imaging, Female, Humans, Male, Middle Aged, Retrospective Studies, Ultrasonography, Appendicitis complications, Severity of Illness Index
- Abstract
Background: Studies have shown that uncomplicated appendicitis can be treated conservatively with antibiotics. It is important to select only those patients with uncomplicated appendicitis when considering conservative management. Recently, a scoring system based on clinical evaluation and ultrasound was developed to improve this selection and aid in shared decision making when considering an antibiotics-first strategy. The aim of this study was to externally validate the scoring system., Materials and Methods: A retrospective cohort study of all adult patients presenting to the emergency department between January 2014 and January 2017 with suspected acute appendicitis based on clinical evaluation and ultrasound was performed. For every patient, a score was calculated using the previously described scoring system. A final diagnosis, subdivided into complicated appendicitis, uncomplicated appendicitis, complicated alternative disease, and uncomplicated alternative disease, was assigned to every patient based on operative findings., Results: A total of 678 patients with suspected acute appendicitis based on clinical and ultrasonography findings were identified, of whom 175 (25.8%) had complicated appendicitis, 491 (72.4%) had uncomplicated appendicitis, and 12 (1.8%) had an alternative disease. Of the 678 patients, 272 had a score of five points or less, of whom 17 (6.2%) had complicated appendicitis, giving a negative predictive value of 93.8%., Conclusions: With the scoring system based on clinical and ultrasonography features, 93.8% of patients predicted to have uncomplicated appendicitis were correctly identified. The scoring system could help identify patients suitable for conservative management in future studies., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
47. Risk Factors Associated with Prolonged Hospital Stay and Readmission in Patients After Primary Bariatric Surgery.
- Author
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Nijland LMG, de Castro SMM, and van Veen RN
- Subjects
- Gastrectomy adverse effects, Humans, Length of Stay, Patient Readmission, Postoperative Complications epidemiology, Postoperative Complications surgery, Retrospective Studies, Risk Factors, Bariatric Surgery adverse effects, Laparoscopy, Obesity, Morbid surgery
- Abstract
Introduction: The introduction of enhanced recovery after surgery (ERAS) has resulted in a decrease in length of hospital stay of patients after bariatric surgery. The general length of hospital stay is 1 day. Some bariatric patients stay longer after an uncomplicated procedure or are readmitted for varying reasons., Objectives: The aim of the present study is to identify risk factors associated with prolonged hospital stay and readmissions., Methods: A retrospective study of all patients who underwent a primary procedure (i.e. Roux-en-Y gastric bypass or sleeve gastrectomy) between January 2016 and January 2019 was performed., Results: A total of 1669 patients who underwent primary laparoscopic Roux-en-Y gastric bypass (70.7%) or sleeve gastrectomy (29.3%) were included. The median length of stay was 1 day (range 1-69 days). In 138 patients (8.3%), a postoperative complication was diagnosed and 89 patients were readmitted (5.3%) within 30 days after discharge. Overall, 348 patients (20.9%) stayed longer than 1 day. Univariable analysis showed that depression, ASA III, sleeve gastrectomy and a perioperative and/or postoperative complication were significantly (p value < 0.05) associated with a prolonged stay. In the multivariable model depression, sleeve gastrectomy and postoperative complication were independent risk factors for prolonged stay. Univariable analysis of risk factors associated with readmission identified depression and perioperative and postoperative complications. Multivariable analysis for readmission demonstrated only presence of a postoperative complication was an independent risk factor., Conclusion: Depression, sleeve gastrectomy and postoperative complications were independent risk factors for prolonged stay. Postoperative complication was an independent risk factor for readmission.
- Published
- 2020
- Full Text
- View/download PDF
48. Treatment strategies in elderly breast cancer patients: Is there a need for surgery?
- Author
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Sierink JC, de Castro SM, Russell NS, Geenen MM, Steller EP, and Vrouenraets BC
- Subjects
- Age Factors, Aged, 80 and over, Breast Neoplasms pathology, Carcinoma, Ductal, Breast pathology, Carcinoma, Intraductal, Noninfiltrating pathology, Carcinoma, Lobular pathology, Cohort Studies, Comorbidity, Female, Humans, Neoplasm Staging, Retrospective Studies, Survival Rate, Breast Neoplasms surgery, Carcinoma, Ductal, Breast surgery, Carcinoma, Intraductal, Noninfiltrating surgery, Carcinoma, Lobular surgery, Mastectomy methods
- Abstract
Background: The aim of this study was to determine the role of surgery in elderly patients with breast cancer., Methods: Between 1999 and 2009, 153 consecutive women, ≥80 years old with breast cancer were treated at our hospital. Surgically and non-surgically treated patients were compared with respect to characteristics and survival., Results: Treatment was surgical in 102 patients (67%). The non-surgically treated patients were older than surgically treated patients, had more co-morbidity and were more often diagnosed with a clinically T3/T4 tumour and distant metastasis. Patients not receiving surgery, had an 11% overall survival rate at 5-year versus 48% in surgically treated patients (P < 0.001). Independent factors for survival were clinical N0 status, M0 status at presentation and surgery., Conclusion: One in three patients of 80 years and older did not have surgical treatment for breast cancer. Patient not treated surgically are older, have more severe co-morbidity and are diagnosed with more advanced disease than patients who underwent surgery.The selection of patients, who have a poor prognosis, is made on clinical grounds not measurable with a common co-morbidity survey. Better and evidence-based selection criteria for surgical and non-surgical treatment in these patients are needed., (Copyright © 2014 Elsevier Ltd. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
49. Incidental findings on total-body CT scans in trauma patients.
- Author
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Sierink JC, Saltzherr TP, Russchen MJ, de Castro SM, Beenen LF, Schep NW, and Goslings JC
- Subjects
- Adult, Female, Humans, Male, Practice Guidelines as Topic, Retrospective Studies, Wounds and Injuries epidemiology, Guideline Adherence, Incidental Findings, Referral and Consultation statistics & numerical data, Tomography, X-Ray Computed methods, Tomography, X-Ray Computed statistics & numerical data, Trauma Centers, Whole Body Imaging methods, Whole Body Imaging statistics & numerical data, Wounds and Injuries diagnostic imaging
- Abstract
Introduction: Total-body Computed Tomography (CT) scans are increasingly used in trauma care. Herewith the observation of incidental findings, trauma unrelated findings, is also increased. The aim of this study was to evaluate the number of incidental findings in adult trauma patients., Patients and Methods: All consecutive trauma patients that underwent total-body CT scanning between January 2009 and December 2011 were analysed. Incidental findings were divided in three categories: category I (potentially severe condition, further diagnostic work-up is required), category II (diagnostic work-up dependent on patients' symptoms) and category III (findings of minor concern, no diagnostic work-up required)., Results: There were 2248 trauma room presentations; 321 patients underwent a total-body CT scan (14.3%). In 143 patients (44.5%), 186 incidental findings were reported. There were 13 category I findings (7.0%), 45 category II findings (24.2%) and 128 category III incidental findings (68.8%). Overall, 18 patients (5.6%) required additional diagnostic work-up. Four patients underwent work-up by additional radiologic imaging. Three patients required further invasive work-up or treatment. Three patients were transferred to another hospital, no extended follow-up was performed. In three patients, there was no documentation of follow-up. Five patients deceased before diagnostic work-up of the incidental finding could start., Conclusion: Total-body CT scanning as part of the evaluation of trauma patients leads to a substantial amount of incidental findings. Documentation of incidental findings and their clinical consequences was incomplete. Therefore, the findings of this study have prompted us to add an item to our electronic trauma room report that obliges residents to report whether or not incidental findings are found during trauma imaging., (Copyright © 2013 Elsevier Ltd. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
50. Images in emergency medicine. Pain in the leg after jogging.
- Author
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de Castro SM, Joosse P, Unlü C, and Steller EP
- Subjects
- Arthralgia diagnosis, Female, Fractures, Stress diagnosis, Humans, Magnetic Resonance Imaging, Middle Aged, Osteoarthritis, Knee, Tibial Fractures diagnosis, Arthralgia etiology, Fractures, Stress etiology, Jogging injuries, Tibial Fractures etiology
- Published
- 2009
- Full Text
- View/download PDF
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