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The synthesis of isatin-derived N , S -acetals using cobalt as a recyclable heterogeneous catalyst in batch and continuous flow is reported for the first time. The present protocol produced high yields, which can be observed from the reaction between ketimines and thiols. Such reactions can also be applied to a gram-scale. In addition, the catalyst is recyclable, economically-viable, and nontoxic as well as easy to prepare. The remarkable features of this new methodology are high conversion and cleaner reaction profiles. [ABSTRACT FROM AUTHOR]

This is the first report of enzymes used as biocatalysts for a 1,2-sulfur addition. In this study, we describe the synthesis of N,S-acetals using an environmentally friendly process with low catalyst loading and in short reaction times using porcine pancreatic lipase, chymosin, and bovine serum albumin (BSA). The hydrogen bond between the enzyme and the N-Boc imine is a key factor in this reaction. [ABSTRACT FROM AUTHOR]

Abstract: A simple, efficient and green methodology for the C−S cross‐coupling reaction using Pd(L‐Pro)2 as a heterogeneous catalyst was developed involving aryl iodides, thiols, green‐solvent and a low catalytic loading of palladium prolinate. In addition, the catalyst turned out to be recyclable and the products were obtained in good to excellent yields. [ABSTRACT FROM AUTHOR]

[Ce(L-Pro)2]2 (Oxa) was used as a recyclable heterogeneous catalyst under mild conditions for the preparation of 2-aryl-2,3-dihydroquinazolin-4(1H)-one derivatives. The one-pot protocol proceeds in ethanol using anthranilamide with several aldehydes at 50-55 °C. The catalyst can be recycled and reused three cycles without significant loss of catalytic activity. [ABSTRACT FROM AUTHOR]

An efficient method has been developed for the preparation of a-aminophosphonates by using zinc di(L-prolinate) as a catalyst under mild reaction conditions. The method has the advantages of high yields, short reaction times, and easy workup conditions. [ABSTRACT FROM AUTHOR]

We developed a novel and highly efficient protocol for the synthesis of important pyrazole derivatives by using some 1,3-dicarbonyl compounds and phenyl hydrazines via a one-pot protocol. As a recyclable heterogeneous catalyst, we used [Ce(l-Pro)2]2 (Oxa). In addition, the catalyst is recyclable, the proline is economically viable and readily available in both enantiomeric forms and the catalyst is insoluble in almost all solvents and may be easily filtered off from the reaction medium. Moreover, this new synthetic protocol features high conversion, short reaction times, a straightforward procedure and cleaner reaction profiles. [ABSTRACT FROM AUTHOR]