5 results on '"craniofacial bone reconstruction"'
Search Results
2. Scattering of therapeutic radiation in the presence of craniofacial bone reconstruction materials.
- Author
-
Toivonen, Joonas, Björkqvist, Mikko, Minn, Heikki, Vallittu, Pekka K., and Rekola, Jami
- Subjects
POLYETHER ether ketone ,FIBROUS composites ,MATERIALS testing ,GLASS fibers ,BACKSCATTERING ,BONE mechanics ,PHOTON beams ,CHROMIUM isotopes - Abstract
Purpose: Radiation scattering from bone reconstruction materials can cause problems from prolonged healing to osteoradionecrosis. Glass fiber reinforced composite (FRC) has been introduced for bone reconstruction in craniofacial surgery but the effects during radiotherapy have not been previously studied. The purpose of this study was to compare the attenuation and back scatter caused by different reconstruction materials during radiotherapy, especially FRC with bioactive glass (BG) and titanium. Methods: The effect of five different bone reconstruction materials on the surrounding tissue during radiotherapy was measured. The materials tested were titanium, glass FRC with and without BG, polyether ether ketone (PEEK) and bone. The samples were irradiated with 6 MV and 10 MV photon beams. Measurements of backscattering and dose changes behind the sample were made with radiochromic film and diamond detector dosimetry. Results: An 18% dose enhancement was measured with a radiochromic film on the entrance side of irradiation for titanium with 6 MV energy while PEEK and FRC caused an enhancement of 10% and 4%, respectively. FRC‐BG did not cause any measurable enhancement. The change in dose immediately behind the sample was also greatest with titanium (15% reduction) compared with the other materials (0–1% enhancement). The trend is similar with diamond detector measurements, titanium caused a dose enhancement of up to 4% with a 1 mm sample and a reduction of 8.5% with 6 MV energy whereas FRC, FRC‐BG, PEEK or bone only caused a maximum dose reduction of 2.2%. Conclusions: Glass fiber reinforced composite causes less interaction with radiation than titanium during radiotherapy and could provide a better healing environment after bone reconstruction. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
3. Scattering of therapeutic radiation in the presence of craniofacial bone reconstruction materials
- Author
-
Joonas Toivonen, Heikki Minn, Jami Rekola, Mikko Björkqvist, and Pekka K. Vallittu
- Subjects
Materials science ,Film Dosimetry ,Osteoradionecrosis ,Glass fiber ,chemistry.chemical_element ,Biocompatible Materials ,Bone and Bones ,030218 nuclear medicine & medical imaging ,law.invention ,Craniofacial Abnormalities ,03 medical and health sciences ,Polyether ether ketone ,chemistry.chemical_compound ,0302 clinical medicine ,law ,Materials Testing ,medicine ,Peek ,Dosimetry ,Radiation Oncology Physics ,Humans ,Scattering, Radiation ,Radiology, Nuclear Medicine and imaging ,Irradiation ,Instrumentation ,radiotherapy ,Titanium ,Photons ,Radiation ,Phantoms, Imaging ,bioglass ,respiratory system ,Plastic Surgery Procedures ,medicine.disease ,fiber reinforced composite ,chemistry ,craniofacial bone reconstruction ,030220 oncology & carcinogenesis ,Bioactive glass ,radiation scattering ,Glass ,Biomedical engineering - Abstract
Purpose Radiation scattering from bone reconstruction materials can cause problems from prolonged healing to osteoradionecrosis. Glass fiber reinforced composite (FRC) has been introduced for bone reconstruction in craniofacial surgery but the effects during radiotherapy have not been previously studied. The purpose of this study was to compare the attenuation and back scatter caused by different reconstruction materials during radiotherapy, especially FRC with bioactive glass (BG) and titanium. Methods The effect of five different bone reconstruction materials on the surrounding tissue during radiotherapy was measured. The materials tested were titanium, glass FRC with and without BG, polyether ether ketone (PEEK) and bone. The samples were irradiated with 6 MV and 10 MV photon beams. Measurements of backscattering and dose changes behind the sample were made with radiochromic film and diamond detector dosimetry. Results An 18% dose enhancement was measured with a radiochromic film on the entrance side of irradiation for titanium with 6 MV energy while PEEK and FRC caused an enhancement of 10% and 4%, respectively. FRC‐BG did not cause any measurable enhancement. The change in dose immediately behind the sample was also greatest with titanium (15% reduction) compared with the other materials (0–1% enhancement). The trend is similar with diamond detector measurements, titanium caused a dose enhancement of up to 4% with a 1 mm sample and a reduction of 8.5% with 6 MV energy whereas FRC, FRC‐BG, PEEK or bone only caused a maximum dose reduction of 2.2%. Conclusions Glass fiber reinforced composite causes less interaction with radiation than titanium during radiotherapy and could provide a better healing environment after bone reconstruction.
- Published
- 2019
4. Paediatric cranial defect reconstruction using bioactive fibre-reinforced composite implant: early outcomes.
- Author
-
Piitulainen, Jaakko, Posti, Jussi, Aitasalo, Kalle, Vuorinen, Ville, Vallittu, Pekka, and Serlo, Willy
- Subjects
- *
CRYOPRESERVATION of organs, tissues, etc. , *HOMOGRAFTS , *RESORPTION (Physiology) , *SKULL surgery , *ARTIFICIAL implants - Abstract
Background: In children, approximately half of cryopreserved allograft bone flaps fail due to infection and resorption. Synthetic materials offer a solution for allograft bone flap resorption. Fibre-reinforced composite with a bioactive glass particulate filling is a new synthetic material for bone reconstruction. Bioactive glass is capable of chemically bonding with bone and is osteoinductive, osteoconductive and bacteriostatic. Fibre-reinforced composite allows for fabricating thin (0.8 mm) margins for implant, which are designed as onlays on the existing bone. Bioactive glass is dissolved over time, whereas the fibre-reinforced composite serves as a biostable part of the implant, and these have been tested in preclinical and adult clinical trials. In this study, we tested the safety and other required properties of this composite material in large skull bone reconstruction with children. Method: Eight cranioplasties were performed on seven patients, aged 2.5-16 years and having large (>16 cm) skull bone defects. The implant used in this study was a patient-specific, glass-fibre-reinforced composite, which contained a bioactive glass particulate compound, S53P4. Results: During follow-up (average 35.1 months), one minor complication was observed and three patients needed revision surgery. Two surgical site infections were observed. After treatment of complications, a good functional and cosmetic outcome was observed in all patients. The implants had an onlay design and fitted the defect well. In clinical and imaging examinations, the implants were in the original position with no signs of implant migration, degradation or mechanical breakage. Conclusions: Here, we found that early cranioplasty outcomes with the fibre-reinforced composite implant were promising. However, a longer follow-up time and a larger group of patients are needed to draw firmer conclusions regarding the long-term benefits of the proposed novel biomaterial and implant design. The glass-fibre-reinforced composite implant incorporated by particles of bioactive glass may offer an original, non-metallic and bioactive alternative for reconstruction of large skull bone defects in a paediatric population. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
5. Craniofacial bone reconstruction with bioactive fiber-reinforced composite implant.
- Author
-
Aitasalo, Kalle M. J., Piitulainen, Jaakko M., Rekola, Jami, and Vallittu, Pekka K.
- Subjects
CRANIOFACIAL abnormalities ,MUSCULOSKELETAL system abnormalities ,GLYCIDYL methacrylate ,OBSTETRICS surgery ,TRIETHYLENETETRAMINE ,THERAPEUTICS - Abstract
Background A novel, bioactive, fiber-reinforced composite implant is a solution to address the shortcomings in craniofacial bone reconstruction. A longitudinal clinical investigation with a follow-up time of 4 years was conducted. Methods A cranial bone reconstruction with the implant was performed on 12 patients. In these patients, the reasons for craniotomies resulting in craniofacial bone defects were traumatic and spontaneous intracranial bleeding as well as infections to the primary reconstruction material. The implant material consisted of a supporting fiber-reinforced framework, porous inner layers, and a bioactive glass (BG; S53P4) filling. The framework and the porous layers were made of a bisphenol-a-glycidyl methacrylate and triethyleneglycoldi-methacrylate (pBisGMA-pTEGDMA) resin matrix, which was reinforced with silanized E-glass. Results In clinical examinations and skull X-rays, the implants were in original positions providing the expected functional and aesthetic outcome at all time points. Conclusion The implants functioned appropriately, which would provide a potential solution for craniofacial bone reconstruction in the future. © 2013 Wiley Periodicals, Inc. Head Neck 36: 722-728, 2014 [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.