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One of the most prevalent forms of cancer worldwide is skin cancer. Determining disease characteristics necessitates a clinical evaluation of skin lesions, but this process is limited by long time horizons and a multiplicity of interpretations. Deep learning techniques have been created to help dermatologists with these issues as a higher patient survival rate depends on the early and precise detection of skin cancer. This research proposed a new approach for binary classification of dermoscopic images for skin cancer. The Improved Grey Wolf Optimizer (IGWO) is used in this technique to fine-tune some hyperparameters' values of various pre-trained deep learning networks to maximize results. SqueezeNet, ShuffleNet, AlexNet, ResNet-18, and DarkNet-19 are the pre-trained networks that were employed. We tested the MED-NODE and DermIS databases in our investigation. Concerning the MED-NODE and DermIS datasets, the proposed method's highest accuracy results are 100% and 97%, respectively. [ABSTRACT FROM AUTHOR]

Background: The COVID-19 pandemic may have adversely affected the early diagnosis of skin cancer. Objective: To compare epidemiological, clinical and histopathological characteristics in patients undergoing cutaneous squamous cell carcinoma (SCC) surgery before and after the beginning of the pandemic. Material & methods: We conducted a cross-sectional study including two case series: (1) patients operated on for SCC in the year after the first state of alarm in Spain (15 March 2020), and (2) patients with SCC operated on in the previous year. Epidemiological, clinical and histopathological variables, tumour stage and risk grade were collected. Results: 248 patients were included (127 undergoing surgery before the pandemic and 121 after the pandemic). After the beginning of the pandemic, the percentage of high-risk SCC significantly increased from 35.3% to 46.2% (p = 0.011). However, no significant differences were found in thickness, perineural invasion or metastases. Conclusions: Although there has not been a significant reduction in the number of SCC operated on after the pandemic, there has been a significant increase in high-risk SCC. All this could lead to an increase in skin cancer mortality in the future. Resumen: Antecedentes: La pandemia de COVID-19 ha podido afectar negativamente el diagnóstico precoz del cáncer de piel. Objetivo: Comparar las características epidemiológicas, clínicas e histopatológicas en los pacientes intervenidos de carcinoma de células escamosas (CCE) cutáneo antes de la pandemia y después del inicio de la pandemia. Material y métodos: Se diseñó un estudio transversal que incluía 2 series de pacientes: 1) pacientes intervenidos de CCE el año posterior a la declaración del confinamiento general en España (15 de marzo de 2020), y 2) pacientes intervenidos de CCE el año previo. Se recogieron variables epidemiológicas, clínicas e histopatológicas, así como el estadio tumoral y el grado de riesgo. Resultados: Se incluyeron 248 pacientes (127 intervenidos antes de la pandemia y 121 intervenidos después de la pandemia). Tras el inicio de la pandemia, el porcentaje de CCE de alto riesgo aumentó significativamente de 32,3 a 45,5% (p = 0,011). No obstante, no se encontraron diferencias significativas en el grosor tumoral, la invasión perineural o la presencia de metástasis. Conclusiones: Aunque no se produjo una reducción significativa en el número de CCE intervenidos después de la pandemia, ha habido un incremento significativo en los CCE de alto riesgo. Todo ello puede conllevar un incremento en la mortalidad por cáncer de piel en el futuro.

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Copyright of International Journal of Health Management Review is the property of International Journal of Health Management Review and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

INTRODUCCCION: Los tatuajes pueden cubrir una lesión cutánea dificultando su reconocimiento. Por ello, resulta relevante conocer las conductas de los tatuadores de nuestra población frente a los nevos melanocíticos. OBJETIVOS: Principal: determinar si los artistas tatuadores de la ciudad de Córdoba, Argentina, poseen conocimiento sobre las características clínicas de lesiones melanocíticas sospechosas de malignidad. Secundarios: conocer las características demográficas de los tatuadores, así como su conducta frente a la piel de sus clientes. MATERIALES Y MÉTODOS: Estudio observacional, transversal y descriptivo mediante encuestas. Se incluyeron tatuadores mayores de 18 años de la ciudad de Córdoba. Se analizaron variables sociodemográficas y laborales. Se realizó estadística descriptiva mediante porcentajes para las variables cualitativas, y las medidas estadísticas media y desviación estándar para las variables cuantitativas. RESULTADOS: Se completaron 31 encuestas entre enero del 2022 a enero del 2023. La mayoría fueron varones (n=22 71%) con una edad media de 32,7 años y secundario completo, (n=17, 54,8%) que trabajan desde hace menos de 5 años como tatuador (n=13, 41,9%). Dieciocho (58,1%) indicaron tener conocimiento sobre nevos, pero 93,5% negaron conocer el ABCDE. Al evaluar imágenes de lesiones melanocíticas, 13 tatuadores obtuvieron un puntaje > 60% de respuestas correctas, lo que representa el 41,9% del total de la muestra. Treinta (96,8%) encuestados evitan tatuar sobre nevos. El 100% de la muestra respondió que le gustaría aprender a detectar cáncer de piel. CONCLUSIÓN: La mayoría de los encuestados desconoce el método ABCDE y falló al identificar lesiones de piel sospechosas de malignidad. Consideramos que los tatuadores podrían ser importantes aliados en la prevención del cáncer de piel.

Entrevista con la Dra. Magdalena de Troya

Introduction: Basal-cell carcinoma is currently the most frequent type of skin cancer, its main risk factor being exposure to ultraviolet radiation. Treatment consists of surgical resection, according to recurrence risk. Post-resection facial reconstruction should be faced according to the aesthetic unit of the face, which will determine the surgical technique. Material and Method: The following clinical case presents the resection of a morpheiform nodular basal-cell carcinoma located on the cheek and nasal wing, and subsequent reconstruction using a Mustardé flap, with successful results. Results: Favorable evolution with complete resection of the tumor lesion and postoperative vitality of the flap. The patient presented a slight nasal deviation that resolved with scar massage. A nasal wing plasty can be considered in the future. Conclusion: We present a facial basal-cell carcinoma clinical case that was safely and effectively treated with a Mustardé flap. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To describe the demographic and histopathological characteristics of patients diagnosed with basal cell carcinomas located on the head in a dermatological center at Quito, Ecuador. MATERIALS AND METHODS: A transversal descriptive study was carried out in patients diagnosed with basal cell carcinoma on the head in a dermatological center at Quito, Ecuador, from September 2019 to September 2021, and were described according to gender, age, skin phototype, head anatomical subunit and histopathological subtype. RESULTS: Two hundred twenty-three cases were obtained. The age group from 61 to 81 years was the most affected by this type of skin cancer. Phototypes III and IV were the most frequently reported. The nose and cheeks were the most frequent anatomical subunits, and the most common histopathological subtype was nodular. CONCLUSIONS: This study obtained results very similar to those previously described in other countries. However, the most frequently reported skin phototypes in our patients were III and IV, a finding that may be related to the ethnic composition of our population. [ABSTRACT FROM AUTHOR]

Background: skin cancer has a high incidence, with an upward trend worldwide. These carcinomas are preventable both by lifestyle changes and by detecting lesions indicative of malignant transformation.Objective: to determine the risk factors for skin cancer in the population of office number 4 of the Delicias Health Area.Method: an epidemiological, observational, analytical study of cases and controls was carried out in the period 2017-2021. The study population consisted of 13 patients (case group) and 26 patients (control group), for a total of 39 cases included, all over 15 years of age. The variables were studied: age, sex, skin color, occupation, time of exposure to the sun, means of protection, contact with chemical substances. The information was obtained from the medical records and a questionnaire, it was analyzed through the percentage calculation, the Chi2 and the odd ratio.Results: participants older than 55 years (38.5 %), male sex (69.2 %) predominated. They had a higher risk of skin cancer: those with white skin color (Chi2: 3.3; OR: 6.4; pConclusions: those over 55 years of age and men predominated, a statistical and causal association was demonstrated between skin cancer and the risk factors studied.

Sunscreening is the main tool for the prevention of UV radiation skin diseases. Even though its use has expanded, its widespread use is far to come because of economic, esthetical and informative barriers. Also, many studies have surfaced in recent years questioning the safety of chemical compounds as well as its impact on health and the environment. In this article we have recollected information about these topics. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To determine the socio-labor factors associated with the use of sunscreen, clothing or a hat to avoid the harmful effects of solar radiation on Peruvian workers. MATERIALS AND METHODS: Cross-sectional analytical study of secondary data analysis performed in 2016 in the most important cities of Peru. The main variables were the use of three implements to avoid solar radiation in Peruvian workers: The use of sunscreen, special clothing, or a cap worn during their work; associating them with socio-labor variables using analytical statistics. RESULTS: There were included 1299 workers surveyed. Health workers (49%), technicians (36%) and those who work in art (36%) were those who least used sunscreen (p value < 0.001). Health workers (49%), technicians (36%) and those who work in art (36%) were those who used sunscreen the least (p < 0.001). In multivariate analysis, those who used sunscreen more frequently had a family member with skin cancer (p: 0.014) and had more hours of outdoor exposure during their work (p: 0.001). The wearing of protective clothing was lower among those who worked more hours outdoors (p: 0.001). Compared to other professions, it was found that health workers (p: 0.006), social activities (p: 0.043), engineering (p: 0.001) and political activities (p: 0.027) wore more caps. on the other hand, those from other professions wore fewer hats than those from security (p: 0.049). CONCLUSIONS: Differences were found in the use of protection means according to profession, being associated with multiple variables. [ABSTRACT FROM AUTHOR]

Copyright of Revista Médica Clínica Las Condes is the property of Editorial Sanchez y Barcelo and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To identify the knowledge, beliefs and attitudes about skin cancer and the use of sun protection measures in a Colombian population. MATERIALS AND METHODS: Cross-sectional survey in patients or companions who attended the outpatient clinics at Clínica Universitaria Bolivariana in Medellin, Colombia, from September, 2019 to March, 2020. The printed surveys evaluated sociodemographic variables, personal and family history of skin cancer, knowledge, beliefs and attitudes about skin cancer and photoprotection measures. RESULTS: A total of 486 surveys met the inclusion criteria and were analyzed; 59.7% were women, with a median age of 42 years; 98.6% of participants were aware of skin cancer and 73.3% considered that the rapid growth of a skin lesion is a sign of malignancy. The most frequent correct belief included the hours of sun-exposure in which the sun was most harmful to the skin (94.9%), and the use of tanning beds as risk factor for skin cancer (82.9%). The most common frequent wrong belief was that children should be exposed to the sunlight to obtain vitamins (84.4%); 77% and 69.5% of participants used physical photoprotection measures and sunscreen, respectively. CONCLUSIONS: We identified a high frequency of correct beliefs and knowledge about skin cancer; however, some characteristics of malignancy are unknown and certain erroneous beliefs persist, in addition, although the use of photoprotection measures is high, they were not always used following the recommendations for its effective use. [ABSTRACT FROM AUTHOR]

Background: during the COVID-19 pandemic, there was difficulty in accessing dermatology consultations, making it impossible to prioritize skin cancer cases. A teledermatology system was designed and implemented, through mobile telephony, for the study of patients with this pathology. Objective: to evaluate the impact of the teledermatology system for the study of skin cancer in patients treated at the Guillermo Fernández Hernández-Baquero Dermatological Hospital during the COVID-19 pandemic. Methods: a descriptive study was carried out to evaluate the impact of teledermatology in 88 patients with lesions suspected of skin cancers, referred from Primary Care and treated at the Guillermo Fernández Hernández-Baquero Dermatological Hospital in the period since April 1 2020 until April 1, 2021. A teledermatology system was designed, of the teleconsultation type with the possibility of remote diagnosis, based on the exchange of images and texts, on an Android mobile device. The descriptive statistical method was used. The results were expressed in tables for better understanding. Results: basal cell carcinoma predominated in 63.6 %. The clinic pathological correlation for basal cell carcinoma was 96.4 %, by teledermatology and by face-to-face consultation, respectively. Simple agreement was 93.2 %. Disagreements were slight for 6.8 %. The level of satisfaction was 95.5 %, very satisfied with the applied teledermatology system. Conclusions: the teledermatology system has technical feasibility, is efficient, useful, with diagnostic accuracy, reliability and reproducibility, being effective in the diagnosis of skin cancer, in unfavorable epidemiological conditions such as the COVID-19 pandemic.

Introduction: The basal cell carcinoma is the most frequent epithelial neoplasm, because it constitutes 60-80 % of all the cutaneous cancers. Objective: To determine the answer to HeberFERON® in patients with basal cell carcinoma. Methods: An observational, descriptive and longitudinal study of 90 patients with basal cell carcinoma to whom HeberFERON® was administered was carried out at Dr. Juan Bruno Zayas Alfonso Teaching General Hospital in Santiago de Cuba, from January, 2017 to December, 2019. Some demographic, clinical variables that responded to the treatment were analyzed. Results: The average age was 63 years; there was a higher incidence of the male sex (58 for 64.4 %) and the cutaneous fototype II (56 for 62.0 %), with lesions located in the nose (42 for 46.7 %), as well as a prevalence of the nodular clinical subtype (41 for 45.6 %). The control of the disease was achieved in 100.0 % of the case material. Conclusions: The HeberFERON® was very useful in patients with basal cell carcinoma, since in more than a half of them a complete response was obtained, with a minimum of adverse events, all of them light and moderate.

OBJECTIVE: To characterize the epidemiology of skin cancer in a second level hospital in Northeast Mexico. MATERIALS AND METHODS: Observational, descriptive, retrospective study, done from January 2019 to December 2021. Records of patients of all ages of both sexes diagnosed with skin cancer were selected. The following were collected: family history, occupation, previous radiotherapy, sun exposure, phototype, precancerous lesions, diagnosis, other lesions, evolution time, size, number, and location of the lesions. RESULTS: Eighty-nine patients, 42 men and 47 women, aged 70 years (IQR 62.7-70.1) were analyzed. The evolution time was 24 months (IQR 27.4-40.7). The size of the lesions was 12.0 mm (IQR 14.2-21.4). The most frequent location was in the head and neck (76.1%), the most frequent type of cancer was basal cell carcinoma (72.2%). In the subtypes of this, the nodular (55.1%) was observed; in squamous cell carcinoma, moderately differentiated (75.0%) and in melanomas, lentigo maligna (66.6%). CONCLUSIONS: The most frequent type of cancer was basal cell, mainly in patients aged 70 to 79 years, located in the head and neck. Likewise, most patients presented single lesions and, among the precancerous lesions, the most frequent was actinic keratosis. [ABSTRACT FROM AUTHOR]

Copyright of Arquivos de Ciências da Saúde da UNIPAR is the property of Associacao Paranaense de Ensino e Cultura and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Given its importance and multidimensionality, health plays an essential role in the public policy field. Skin cancer is the most common type of neoplasm found in Brazil and is considered a public health problem. In this regard, this research addresses the issue of skin cancer with a diagnosis of its incidence in the municipality of Campos dos Goytacazes, Rio de Janeiro State, Brazil, based on the Hospital Cancer Registry (RHC, abbreviation in Portuguese). These records obtained data from all patients seen at a reference hospital (Hospital Escola Álvaro Alvim) who were diagnosed with skin cancer between 2012 and 2017, totaling 656 cases. A descriptive statistical analysis of variables such as age, occupation, tumor location, neighborhood, and gender was used to profile skin cancer patients in the municipality, identifying the sectors of the area where the local population is most affected by the disease, besides any environmental factors that may be related and the most affected race. The results of the study demonstrate that the light-skinned population (69.1%) and the age group over 55 years old (predominantly from 70 to 74 years for basal cell carcinomas and from 80 to 84 years for squamous cell carcinomas) constitute the most affected group by skin cancer. This information should support public policies and campaigns among the population aiming to improve strategies for its prevention and early diagnosis. [ABSTRACT FROM AUTHOR]

BACKGROUND: Skin cancer is one of the most frequent and preventable neoplasms. Its prevalence is directly related to individual cumulative radiation exposure. OBJECTIVE: To describe the clinical and sociodemographic characteristics of a Colombian population with melanoma and non-melanoma skin cancer cared at a dermatological center in Bogotá, Colombia. MATERIALS AND METHODS: A descriptive retrospective study was performed in a dermatologic center in Bogotá, Colombia. We characterized all the cases of skin cancer that the institution handled from January 2016 to January 2020 according to the patients' sociodemographic and clinic characteristics. Relative and absolute frequencies were used to describe patients. p values were calculated with Mann-Whitney U-tests for continuous variables and χ2 or Fisher's test for categorical variables. RESULTS: Of 400 patients, 53% (n = 212) were female. The mean age at diagnosis was 72 years. Mixed basal cell carcinoma (n = 160), infiltrating squamous cell carcinoma (n = 50), and lentigo maligna (n = 7) were the most frequent histological subtypes for each skin cancer variant. CONCLUSIONS: Basal cell carcinoma was the most common skin cancer subtype and patients with phototype II had a higher frequency in melanoma skin cancer. Further studies are necessary to improve early diagnosis. [ABSTRACT FROM AUTHOR]

BACKGROUND: Basal cell carcinoma is the most frequent skin cancer; it has been classically classified into two groups of recurrence risk for its management. OBJECTIVES: To describe the characteristics of primary tumors managed by conventional surgery, according to institutional guidelines, describing the findings of tumors with positive margins or recurrences and analyzing the associated factors. MATERIALS AND METHODS: A retrospective descriptive study was carried out seeking the relationship between margin compromise and tumor recurrence, with the risk classification used in the National Institute of Cancerology of Colombia, by comparing the demographic, clinical and histological parameters of the tumors managed with conventional surgery from 2008 to 2010 with the previously mentioned outcomes. Recurrence free survival was determined using the Kaplan-Meier method. RESULTS: 429 tumors were surgically removed in 335 patients, obtaining free margins in 96.5% of resections based on the three-risk group approach. Of those with positive margins, 12 belonged to the high risk group, 3 to the medium risk group and none to the low risk group. Five recurrences occurred, 3 in the high risk group and two in the medium one, with a median occurrence of 11 months. CONCLUSIONS: The classification with three risk groups allows the adequate management of basal cell carcinoma, with little persistence and tumor recurrence, allowing to decrease the need of Mohs micrographic surgery or excessive tissue removal. [ABSTRACT FROM AUTHOR]

Introduction: skin cancer in elderly has not been characterized in Guantanamo. Objective: characterize the patients admitted to the nursing homes "Caridad Jaca" and "San José" in the city of Guantánamo with a diagnosis of skin cancer in the period 2017-2019. Method: it was conducted an observational, prospective and cross-sectional study with all the elderly (n=256) with skin cancer (n=15). Studied variables: age, sex, place of birth and lived, personal pathological history, skin phototype, characteristics of the lesion, clinical dermatoscopic and histopathological diagnosis. Results: 5.9% of the elderly were diagnosed with skin cancer. It was more common in men (53.4%), range age from 60 to 79 (53.4%), were born or lived in urban areas and with skin phototype III (40.0%). 100.0% of the patients were exposed to sunlight, 86.7% without photo-protection means. The cancer was more localized in the face area (66.7%), had between 3 and 4 years of evolution (60.0%) and basal cell carcinoma (46.6%) was the most frequent. Clinical, dermatoscopic and histopathological diagnosis correlation was observed in 80.0 % of the cases. Conclusions: the rate of skin cancers in erderly is low, however, more attention is needed to ensure early diagnosis of this disease

The case report of a 72 years old man who presented a dorsal cutaneous neoplasm is described, reason why he was assisted in a multidisciplinary way in 2 hospitals from Santiago de Cuba. Given the preoperative diagnosis of skin basal cell epithelioma the tumor was removed in an ambulatory way. The result of the pathologic study didn't confirm this diagnosis, but it corroborated that it was an atypical fibroxanthoma. With the wide surgical margins of security the patient's cure was achieved.

Presentado en sesión de 22 de junio de 1960

El cáncer de piel es la neoplasia maligna más frecuente en Uruguay así como a nivel mundial, donde muere una persona cada menos de cuatro días por ésta causa. La medida de prevención primaria más efectiva es tener hábitos de fotoprotección, lo cual se consigue mediante la educación en salud y campañas preventivas. En el contexto de la Campaña de Prevención de Cáncer de Piel 2017, entre otras actividades, se realizó examen físico a funcionarios del Hospital de Clínicas y un cuestionario sobre hábitos y conocimientos de fotoprotección. La amplia mayoría de los individuos considera que cuenta con información suficiente sobre cómo protegerse del sol, que proviene, en un 39% de los casos de la televisión. Aún asi, el 41% de ellos, sólo se protege en ocasiones especiales como viajes y verano y únicamente 3 de los participantes emplea medidas adecuadas. Con respecto a campañas previas, 94% no recordaba otra campaña de prevención de cáncer de piel y era la primera vez que concurría a una el 99% de los individuos, lo que pone en manifiesto la necesidad de reforzar la planificación y ejecución de campañas y medidas efectivas para la promoción y prevención del cáncer de piel en los próximos años a fin de lograr disminuir la incidencia de cáncer de piel que continúa en aumento.

Introducción: la cirugía micrográfica de Mohs es una técnica quirúrgica especializada para el tratamiento del cáncer de piel no melanoma. La histopatología cumple un rol fundamental, y la elección de la tinción es un punto de controversia. Objetivos: comparar el rendimiento de las tinciones de hematoxilina y eosina (HyE) versus azul de toluidina (AT) durante la cirugía. Método: estudio observacional, descriptivo y transversal a partir de noviembre de 2017 hasta mayo de 2018. Se incluyeron las láminas empleadas durante la cirugía en el período mencionado. Estas fueron analizadas por el cirujano de Mohs, tres residentes y una dermopatóloga. Se valoró el rendimiento de ambas tinciones, teniendo en cuenta las características celulares y los elementos del estroma. Resultados: se estudiaron 23 tumores (16 carcinomas basocelulares y 7 carcinomas espinocelulares). Al observarse al microscopio óptico tanto con la tinción de AT como con HyE no se encontraron diferencias significativas entre ambos grupos en lo global, sólo en algunas características, especialmente con la HyE. Conclusiones: es el primer trabajo en Uruguay que compara la eficacia de las dos tinciones durante la cirugía micrográfica de Mohs. Como conclusión tanto la tinción de HyE como el AT son muy buenas técnicas para el diagnóstico de carcinomas cutáneos.

Introduction: The basal cell carcinoma is the most frequent epithelial neoplasm, because it constitutes 60-80 % of all the cutaneous cancers. Objective: To determine the answer to HeberFERON® in patients with basal cell carcinoma. Methods: An observational, descriptive and longitudinal study of 90 patients with basal cell carcinoma to whom HeberFERON® was administered was carried out at Dr. Juan Bruno Zayas Alfonso Teaching General Hospital in Santiago de Cuba, from January, 2017 to December, 2019. Some demographic, clinical variables that responded to the treatment were analyzed. Results: The average age was 63 years; there was a higher incidence of the male sex (58 for 64.4 %) and the cutaneous fototype II (56 for 62.0 %), with lesions located in the nose (42 for 46.7 %), as well as a prevalence of the nodular clinical subtype (41 for 45.6 %). The control of the disease was achieved in 100.0 % of the case material. Conclusions: The HeberFERON® was very useful in patients with basal cell carcinoma, since in more than a half of them a complete response was obtained, with a minimum of adverse events, all of them light and moderate. [ABSTRACT FROM AUTHOR]

Copyright of Revista Habanera de Ciencias Médicas is the property of Universidad de Ciencias Medicas de La Habana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: cancer is one of the most relevant challenges of our times for the man, it constitutes one of the illnesses of greater incidence on the world population, until 2020 19,3 millions of new cases were reported and 50,6 millions of people living with cancer. Objective: to characterize the incidence of cancerin the Polyclinic ¨René Vallejo Ortiz¨ from Manzanillo municipality during the year 2019-2020. Method: an observational-descriptive-retrospective study was carried out. The sample group was made up by 86 patients with a diagnosis of cancer by biopsy. Variables were studied as: age, sex, type of cancer and diagnosis the years. The data were processed according to the descriptive statistics. Results: the greatest percentage of cancer was contributed by the age group 60-79 years (52, 3 %), the female sex (59,3 %) and the years 2020 (53,5 %); the most frequent type during the study period was the skin cancer (47,7 %) and the lung cancer (15 %) and the female sex skin (19,8 %), lung (11,6 %) and breast (9,2 %) and in men were skin (28 %), lung (3,4 %) and prostate gland (3,4 %). Conclusion: the incidence of cancer in the studied period was upward, prevailing in advanced age, the female sex and as main locations skin and lungs.

The incidence of malignant skin neoplasms of the head and neck has been increasing in recent years, since many of these will require surgical management, dermatologists should be familiar with facial reconstruction techniques using skin flaps. The V-Y flap is a type of advancement flap, its purpose is to replace a rectangular defect by executing a triangular island adjacent to the defect while maintaining established measures to conserve the vascular supply. Finally, a secondary V-shaped defect is formed that will close forming a Y-shape, hence its name "V-Y flap". Knowledge of this technique is useful for facial reconstruction since it allows to achieve oncological, functional, and aesthetic criteria. The objective of this article is to discuss the different uses of the V-Y flap and its variants for the reconstruction of localized defects in the lips, cheeks, and nose. [ABSTRACT FROM AUTHOR]

Introducción: en Guantánamo no está esclarecida la frecuencia de las lesiones cutáneas en pacientes ingresados en los hogares de ancianos.Objetivo: determinar la frecuencia de dermatosis precancerosas y cancerosas en pacientes de los hogares de ancianos “Caridad Jaca”, “Santa Catalina” y “San José” del municipio Guantánamo en el período 2016-2017.Método: se realizó un estudio observacional, prospectivo, descriptivo y transversalcon todos los ancianos (N=318) y en los afectados (n=70) se precisó el sexo, edad, fototipo cutáneo, tipoy localización de las lesiones.Resultados: el 22,1 % de los ancianos presentó dermatosis precancerosas y cancerosas. Estas fueron más comunes en hombres (56,0%), con 70 a 79 años de edad (42,8 %), fototipo cutáneo III (50,0 %) y se localizaron en la cara (32,8 %). Se diagnosticaron dermatosis precancerosas en el 84,3 % de los pacientes y la más común fue la queratosis actínica (78,6%) y dermatosis cancerosas en el 15,7 % de ellos y la más frecuente fue el carcinoma basocelular (8,6%).Conclusiones: en los pacientes ancianos que se estudiaron se diagnosticaron las dermatosis precancerosas y cancerosas que no se habían documentado con anterioridad, lo que revela la importancia de las acciones dirigidas al pesquisaje de estas lesiones cutáneas.

Introducción: en Cuba una de las exigencias sociales es el estudio del cáncer de piel en la población de adultos mayores. Objetivo: caracterizar aspectos clínicos-epidemiológicos en pacientes con diagnóstico probable de CP ingresados en los hogares de ancianos "Caridad Jaca" y "San José" de la ciudad de Guantánamo durante el año 2017. Método: se realizó un estudio observacional, prospectivo y transversal con todos los ancianos (n=256) y en aquellos con probable cáncer de piel (n=15) se precisó la edad; sexo; lugar de nacimiento, dónde vivió; antecedente patológicos personales; foto tipo cutáneo; características de la lesión; diagnóstico clínico y dermatoscópico. Resultados: en el 5,9 % de los ancianos se diagnosticó un cáncer de piel. Fue más común en hombres (53,4 %), con 70 a 79 años (53,4 %), nacidos o que vivieron en áreas urbanas y foto tipo cutáneo III (40,0 %). El100.0 % se expuso a la luz solar, el 86,7 % sin medios de foto protección. El cáncer se localizó más en la cara (66,7 %), tenía un área inferior a un centímetro (46,6 %), entre 3 y 4 años de evolución (60,0 %), fue una lesión única (86,7 %) y el carcinoma basocelular (46,6 %). En el 80,0 % de los casos se apreció correlación diagnóstico clínica-dermatoscópica. Conclusiones: fue baja la frecuencia del cáncer de piel en los ancianos. Sin embargo, se requiere prestar más atención al aseguramiento del diagnóstico precoz de esta enfermedad.

RESUMEN Objetivo: Describir las características clínicas y patológicas del carcinoma basocelular. Métodos: Se realizó un estudio descriptivo y retrospectivo de serie de casos en el Servicio de Cirugía Plástica Ocular del Instituto Cubano de Oftalmología “Ramón Pando Ferrer”, desde enero del año 2016 a diciembre de 2018. Se incluyeron todos los pacientes con diagnóstico histopatológico posoperatorio de carcinoma basocelular en el período de estudio. La muestra quedó conformada por 54 pacientes y se caracterizó según el año del diagnóstico, la edad, el sexo, el color de la piel, la procedencia, el grado de diferenciación celular, el párpado afectado, la localización palpebral, el diagnóstico preoperatorio y el diagnóstico histopatológico posquirúrgico. Resultados: El 57,4 % de los pacientes fueron del sexo femenino. El grupo más afectado fue el de 60-79 años con el 53,7 % de los casos, con una edad media de presentación de 54,57 años. El 88,9 % de la muestra fueron de piel blanca. En el 79,6 % se afectó el párpado inferior y en el 64,8 % el tercio interno. El 64,8 % fueron carcinoma basocelular poco diferenciados y la concordancia entre el diagnóstico clínico y el histopatológico fue del 85,2 %. Conclusiones: El carcinoma basocelular es más frecuente en el sexo femenino, en los adultos mayores y en los pacientes de piel blanca. En cuanto al grado de diferenciación celular, es poco diferenciado, y se localiza fundamentalmente en el tercio interno del párpado inferior. Existe concordancia entre el diagnóstico clínico y el histopatológico en la mayoría de los pacientes.

RESUMEN El melanoma amelanótico es una de las neoplasias con mayor índice de mortalidad por su alta agresividad y baja probabilidad diagnóstica. Afecta a la población de todo el orbe, más frecuente en caucásicos, con predisposición genética y factores de riesgo como la exposición al sol. Presenta tasas de supervivencia menor a 10 % a 5 años y de recurrencia elevadas; con evidencia de procesos metastásicos a distancia en órganos como cerebro, tejido celular subcutáneo, pulmón, peritoneo, hueso, lo que ensombrece el pronóstico. Se presenta el caso de una paciente de 21 años de edad que acude al hospital por presentar lesiones equimóticas, nódulos subcutáneos y cefalea hemicránea izquierda de dos meses de evolución. Se le realizó tomografías de tórax abdomen y resonancia magnética de cráneo y evidenciaron diseminación metastásica. Se realizó estudio histopatológico con inmunohistoquímica que informó melanoma amelanótico.

BACKGROUND: According to the World Health Organization, one of three patients diagnosed with cancer has skin cancer. OBJECTIVES: To describe the epidemiological aspects of keratinocyte carcinoma in the population of the Dermatology and Pathology services of the General Regional Hospital of IMSS No. 220 General José Vicente Villada, Toluca, Mexico, and to determine the clinical-pathological concordance of these lesions. MATERIALS AND METHODS: A cross-sectional, retrospective, descriptive and observational study with the registry of patients with biopsy who attended the Dermatology Service from January 1 to December 31, 2013. Descriptive statistics and kappa concordance analysis were used for the validation of the results. RESULTS: Ninety-eight clinical files were included with a total of 104 suspicious lesions. 78% of the lesions were basal cell carcinoma, 16% squamous cell carcinoma and 6% benign lesions. It was more frequent in the female sex (51%) and the most affected age group was older than 70 years (50%). The clinicopathological concordance of keratinocytic skin cancer had a kappa coefficient of 0.7074, a good grade. CONCLUSIONS: Keratinocyte carcinoma continues to be the most frequent neoplasm in Mexico. Due to the good degree of agreement obtained, an adequate training and preparation of the doctors who carry out the clinical diagnosis and the therapeutic approach is deduced. [ABSTRACT FROM AUTHOR]

BACKGROUND: Skin cancer is one of the most frequent malignant neoplasms worldwide; in this group the basal cell carcinoma is the most common; nevertheless, different clinical variants exist that modify the natural evolution of the disease. CLINICAL CASE: A 50-year-old male patient with history of uncontrolled schizophrenia in who a giant basal cell carcinoma was found, but, in spite of its size and evolution, no invasion to deep tissue was found. CONCLUSIONS: Giant basal cell carcinoma is a rare and aggressive subtype of basal cell carcinoma and, therefore, requires multidisciplinary management, with some difficulties in choosing the appropriate treatment. [ABSTRACT FROM AUTHOR]

Background: The development of skin cancer is closely related to high exposure to UV radiation. Lifeguards are at an increased risk of excessive sun exposure., Objectives: The main objective of this study was to measure the exposure of Barcelona's beach lifeguards to UV radiation., Methods: Measurements in the work chair were taken every 30min on a typical working day from 10:45 am to 19:15 pm. These measurements were carried out on four different days. These data were used to calculate the erythematous doses received during working hours, as well as those potentially received throughout the summer season. Vitamin D production was also estimated for the four days that the radiation received was measured, and the amount generated was calculated for the entire summer season., Results: Exposure to UV radiation among Barcelona lifeguards far exceeds safety limits. In some locations, the exposure to UVB radiation is more than 16 times the minimum erythematous dose for phototype II skin., Limitations: This study assessed the radiation received during only four days. However, is a much higher number than most of the published papers., Conclusion: Although the health risks of excessive exposure to UV radiation are known, Barcelona's beach lifeguards are insufficiently protected., (Copyright © 2023 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)

Objetivo: Describir la frecuencia, magnitud y tratamiento de los diversos tipos de melanoma diagnosticados en el Hospital de Especialidades Carlos Andrade Marín (HECAM) de la ciudad de Quito. Métodos: Se realizó un estudio transversal de los pacientes que acudieron a la clínica de Melanoma del servicio de Dermatología del HECAM, durante los años 2013 a 2018. Se tomó en cuenta a todos los pacientes con histopatología diagnóstica de cualquier tipo de melanoma maligno y que tuvieron tratamiento y seguimiento. Se clasificó a los pacientes según el estadiaje clínico y patológico después de la biopsia y se obtuvieron datos sobre su tratamiento y pronóstico. Resultados: Durante un período de cinco años aproximadamente se obtuvieron datos de 77 sujetos con diagnóstico de melanoma maligno, no existieron diferencias en la presentación por sexo (hombres 49,3% frente a mujeres 50,7%), y edad (hombres 68,5 años frente a mujeres 65,7 años). El tipo de melanoma maligno más frecuente en mujeres fue el melanoma maligno de extensión superficial (58,9%) y en hombres el melanoma invasor (42,1%), el tratamiento más frecuente fue la escisión y cierre directo en los casos menos severos, mientras que en estadiajes severos fue la escisión seguida de injerto. Conclusiones: El melanoma maligno es un tipo de cáncer que en nuestro medio afecta por igual a hombres y mujeres, sin embargo, en el Ecuador parece ser que se manifiesta con mayor severidad en los hombres. Las características clínicas de este tipo de patología retrasan el diagnóstico, por lo que es necesario educar a la población para la detección temprana de lesiones sospechosas de melanoma maligno.

BACKGROUND: Sun protection during childhood may reduce the risk of developing skin cancer later in life. OBJECTIVE: To evaluate the comprehension of sun protection methods, level of recall and impact on sun-protective behaviors, three- and six-months after the intervention. MATERIAL AND METHOD: A cluster randomized clinical controlled, single-blinded trial, performed from January 2016 to December 2017, in which cluster random assignment of preschool children of eight private and public schools in Medellin, Colombia was done. Children were randomly assigned to an intervention (IG) or control group (CG). The IG was provided with a printed and illustrated sun-protection story book, presented by a professional actor during 20-minutes monologue. The CG was provided with an educational flyer, explained by a registered nurse. RESULTS: 651 kindergarten students met the inclusion criteria (IG: 329, CG: 319). Immediately after the initial intervention, the IG demonstrated a better understanding of sun protection methods and behaviors. Overall, participants showed a trend toward variaimprovement of sun protection behaviors at the three time points of the study; although no statistically significant differences were observed between groups. CONCLUSIONS: Our results suggest that cognitive interventions in kindergarten children may lead to long-lasting improvements in sun protection behaviors. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To analyze changes in the expression of Hsp70, Hsp90, p53 and DNA fragmentation in BALB/c mouse skin cells exposed to UVA, UVB and UVC radiation, as well as the decrease in skin damage using the antioxidants superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) topically. MATERIAL AND METHOD: A basic experimental study was done from March 2016 to February 2019 in which BALB/c mice were exposed to UVA, UVB and UVC radiation for 30, 60 and 90 minutes, skin extracts were obtained. The proteins were characterized by SDS-PAGE and Western-blot, and immunodetected with monoclonal antibodies. The DNA was evaluated for its integrity by electrophoresis in agarose gels. RESULTS: Changes in the morphology of the skin exposed to UV light were observed, Hsp70 and Hsp90 modified their expression by UV light (UVA, UVB, UVC) at different exposure times, this was also the case with p53, where its expression increased at 30 and 60 minutes of exposure. By using a cream with antioxidants discreetly decreased the expression of Hsp70 and Hsp90, while p53 increased. The DNA was fragmented mainly with UVB and UVC light. CONCLUSIONS: UV light generates cellular stress modifying the expression (increase) of Hsp70, Hsp90 and p53 proteins. Also, the fragmentation of DNA was observed, due to UV light. [ABSTRACT FROM AUTHOR]

The case report of a 72 years old man who presented a dorsal cutaneous neoplasm is described, reason why he was assisted in a multidisciplinary way in 2 hospitals from Santiago de Cuba. Given the preoperative diagnosis of skin basal cell epithelioma the tumor was removed in an ambulatory way. The result of the pathologic study didn't confirm this diagnosis, but it corroborated that it was an atypical fibroxanthoma. With the wide surgical margins of security the patient's cure was achieved. [ABSTRACT FROM AUTHOR]

Introducción: La sobreexposición solar se asocia al desarrollo de diversas enfermedades de la piel entre ellas, el cáncer de piel. Evitar la exposición solar utilizando diferentes medidas de fotoprotección ha resultado beneficioso para evitar el riesgo de cáncer. Objetivo: Este estudio evaluará la frecuencia con la cual los padres de familia utilizan medidas fotoprotectoras en sus hijos. Metodología: Este fue un estudio descriptivo-prospectivo en el que se realizó una encuesta pasada a los padres de familia de niños de 3-12 años. Resultados: Más de la mitad de los participantes (64%) reportaron usar métodos de protección solar en sus hijos. El método más utilizado fue la gorra, y prevenir quemaduras fue la razón primaria para utilizar medidas de protección solar. Discusión: Aunque el uso regular de métodos de protección solar para los niños es frecuente, el principal es el uso de gorra que no es un método ideal por sí solo.

Background: The COVID-19 pandemic may have adversely affected the early diagnosis of skin cancer., Objective: To compare epidemiological, clinical and histopathological characteristics in patients undergoing cutaneous squamous cell carcinoma (SCC) surgery before and after the beginning of the pandemic., Material & Methods: We conducted a cross-sectional study including two case series: (1) patients operated on for SCC in the year after the first state of alarm in Spain (15 March 2020), and (2) patients with SCC operated on in the previous year. Epidemiological, clinical and histopathological variables, tumour stage and risk grade were collected., Results: 248 patients were included (127 undergoing surgery before the pandemic and 121 after the pandemic). After the beginning of the pandemic, the percentage of high-risk SCC significantly increased from 35.3% to 46.2% (p=0.011). However, no significant differences were found in thickness, perineural invasion or metastases., Conclusions: Although there has not been a significant reduction in the number of SCC operated on after the pandemic, there has been a significant increase in high-risk SCC. All this could lead to an increase in skin cancer mortality in the future., (Copyright © 2023 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)