The importance and versatility of derivatives of quinolines is well established in many forms of drugs, potential use of lanthanide complexes as diagnostic molecule have also been reported in literature but studies on biological aspects of complexes of lanthanides related with bioactive species are lesser. The constructions and characterizations of lanthanide complexes are currently of great interest because of their unique physico-chemical properties and various applications in medical field. The present work describes the synthesis, spectral and biological investigations on the complexes of quinoline derivatives with Gd (III) ions in agreement to Green chemistry approach. The magnetic moment of Gd (III) complexes showed slightly higher-values which originated due to low J-J separation leading to thermal population of next higher energy J levels and susceptibility due to first order Zeeman Effect. For various peaks of Gd (III) Intensity (Judd Oflet T2, T4, T6 and oscillator strength Pobs×106), Bonding b1/2, Symmetry (T4/T6) and Cordination (T4/T2) RMS deviation σ parameters have been computed using partial and multiple regression methods. In this research investigations on micellar doped Gd(III) systems have been reported first time. Antimicrobial activities of compounds have also been determined. Keywords: Quinoline, Gd (III), Antimicrobial activity, bonding parameters. Title: Variation in Spectral Parameter of Gd (III) ion with Bioactive N, O-Containing -Heterocyclic Aromatic Ligand Author: Shubh laxmi, Jatolia S.N., Bhojak N, Regar O.P International Journal of Novel Research in Physics Chemistry & Mathematics ISSN 2394-9651 Vol. 9, Issue 2, May 2022 - August 2022 Page No: 1-5 Novelty Journals Website: www.noveltyjournals.com Published Date: 24-May-2022 DOI: https://doi.org/10.5281/zenodo.6575560 Paper Download Link (Source): https://www.noveltyjournals.com/upload/paper/Variation%20in%20Spectral-24052022-1.pdf, International Journal of Novel Research in Physics Chemistry & Mathematics, ISSN 2394-9651, Novelty Journals, Website: www.noveltyjournals.com, {"references":["[1]\tWilkinson G, Gillard R and Mc J. Cleverty, Comprehensive Coor. Chem Pergamon Press Oxford, Chapter 39. (1987).","[2]\tMisra S.N. and M. Indira Devi. The synthesis and determination of the octacoordinated structure of Pr (II1)and Nd(II1) complexes with β-diketones and diols in non aqueous solutions: evidence of some participation of π-electron density of diols with Pr(II1) and Nd(II1) in complexation. Spectrochim. Acta A. (53) 1941-1946 (1997).","[3]\tWybourne B G. Spectroscopic Properties of Rare Earth. Inter Conference. New York (1955).","[4]\tHufner S. Optical Spectra of Transparent Rare Earth Compounds. Academic Press, New York, (1978).","[5]\tMisra S.N. and Indira Devi M., \"The synthesis and determination ofthe octacoordinated structure of Pr (II1) and Nd (II1) complexes with β-diketones and diols in non aqueous solutions: evidence of someparticipation of n- electron density of diols with Pr(II1) and Nd (II1) in complexation\", Spectrochim. Acta A, (53) 1941-1946 (1997).","[6]\tSudhindra N., Ramchandria G., Minaz Gagnani A., Ram Shukla S., Indira Devi M.. Absorption SpectralStudies Involving 4f-4f Transitions as Structural Probe in Chemical and Biochemical Reactions andComposional Dependence of Intensity Parameters. Appl. Spectroscopy Rev., 38 (4) 433-493 (2003).","[7]\tMartin R.B., Structural Chemistry of Calcium: Lanthanides as probes, in: T.G. Spiro (Ed), Calcium in Biology. (237) 198.","[8]\tJudd B. R., Optical Absorption Intensities of Rare Earth Ions. Phys .Rev. (127) 750-761 (1962).","[9]\tOfelt G.S., Intensities of crystal spectra of rare earth ions. Phys J. Chem. Phys. 37 (3) 511-520 (1962)","[10]\tCarnall W.T., Fields P.R., Rajnak K.., Electronic energy levels in the Trivalent Lanthanide Aquo Ions. Pr3+, Nd3+, Pm3+, Sm3+, Dy3+, Ho3+, Er3+ and Tm3+. J. Chem. Phys. (49) 4424-4442 (1968).","[11]\tBhojak N, Jain R, Lavi K, Soni K P and Tater PC. Micellar Investigations on Hypersensitive Transitions for Doped Pr(III) Ion in Saturated Alcoholic Solution of Semicarbazones Asian J Chem. 17(4) 2765 (2005)","[12]\tBhojak N, Jain R and Soni KP. Characterization of Some PR (III) Complexes of Semicarbazones on the Basis of Electronic Spectral Parameters. Oriental J Chem 21(2) 361 (2005).","[13]\tSoni K P, Jain R, Popli A, Tater PC, Bhojak N. Electronic Spectral Study and Thermodynamic Characterization of Doped Nd(III) Ions in various Semicarbazones. Asian J Chem. (17) 964-968 (2005).","[14]\t Bhojak N and Singh B. Microwave Assisted Synthesis, Spectral and Antibacterial Investigations on Complexes of Mn (II) with Amide Containing Ligands. Rasayan J Chem. 1(1) 105-109(2008).","[15]\tJatolia S.N, Bhandari H.S, Bhojak N, International Advanced Research Journal in Science, Engineering and Technology 1 4, 201-204,(2014)."]}