1. Metabolomic profiling in neuroblastoma
- Author
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Quintás G, Yáñez Y, Gargallo P, Juan Ribelles A, Cañete A, Castel V, and Segura V
- Subjects
biomarker, childhood neuroblastoma, metabolome, prognosis, risk stratification - Abstract
Previous studies on several cancer types show that metabolomics provides a potentially useful noninvasive screening approach for outcome prediction and accurate response to treatment assessment. Neuroblastoma (NB) accounts for at least 15% of cancer-related deaths in children. Although current risk-based treatment approaches in NB have resulted in improved outcome, survival for high-risk patients remains poor. This study aims to evaluate the use of metabolomics for improving patients' risk-group stratification and outcome prediction in NB.
- Published
- 2020