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Body piercing has become popular among people of all ages, inspired by religious convictions, personal aesthetics, and cultural influences. Piercings in the oral cavity frequently involve the lip, buccal mucosa, frenulum, and tongue with needles, hooks, and rings. However, these piercings might cause long-term problems to both the hard and soft tissues of the mouth. Our case report emphasizes the relevance of comparing clinical and histological results to provide an accurate diagnosis and appropriate treatment., Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Shrinivaasan et al.)

Cherubism is a rare benign disease, clinically characterized by progressive, asymptomatic, and bilateral expansion of the jaws. Both familial and sporadic cases have been reported. Typically, first signs and symptoms appear in early childhood between 2 and 5 years of age, followed by gradual progression of lesions until puberty and remission before the 4th-5th decades. A treatment protocol for cherubism has not been yet standardized and treatment options vary between conventional surgical and non-invasive approaches. The purpose of this clinical report is to present a comprehensive diagnostic and conservative treatment approach of a 7-years old male with familial cherubism. At age 7 with asymptomatic mild bilateral swelling of the cheeks were observed. The team approach management of the case was based on intranasal calcitonin for 2 years combined with surgical removal of impacted teeth, orthodontics, and prosthodontics. Complete regression was achieved, which was persistent for 8 years post treatment.

Cherubism is a non-neoplastic, rare, hereditary childhood disease of bone characterized by bilateral enlargement of the jaws caused by bone degradation and replacement by fibrous tissue. The affected child is reminiscent of the cherub portrayed in Renaissance art. We report the clinicopathological and radiographic features of cherubism and review of literature.

Four young children who presented with acute thalamic syndrome within a few days after onset of measles infection are reported from the University of Catania, Italy.