Search

Your search keyword '"autism like phenotype (ALP)"' showing total 3 results
Start Over Descriptor "autism like phenotype (ALP)"
3 results on '"autism like phenotype (ALP)"'

1. Early Screening and Risk Factors of Autism Spectrum Disorder in a Large Cohort of Chinese Patients With Prader-Willi Syndrome

Author

Xuejun Kong, Junli Zhu, Ruiyi Tian, Siyu Liu, Hannah T. Sherman, Xiaoying Zhang, Xiaojing Lin, Yan Han, Zhi Xiang, Madelyn Koh, Clara Hobbie, Bryan Wang, Kevin Liu, Jun Liu, Yueping Yin, and Guobin Wan

Subjects
Prader-Willi Syndrome (PWS), Autism Spectrum Disorder (ASD), autism like phenotype (ALP), weight, height, Psychiatry, RC435-571
Abstract

Previous studies regarding the prevalence of Autism Spectrum Disorder (ASD) in patients with Prader-Willi Syndrome (PWS) have implicated heterogenous findings. Additionally, the early screening of ASD high-risk population for ASD and identifying ASD risk factors in PWS patients have not been explored. This study included 218 Chinese PWS patients aged 3 months to 18 years old. 78% of subjects were identified as high risk for ASD by ASQ-3 Communication domain score for those younger than 3 years of age and 84% of subjects were classified as high risk for ASD by the GARS-3 for those aged 3 years and older. Among PWS clinical measurements, under-height (P = 0.0186), overweight (P = 0.0248), and obstructive sleep apnea (P = 0.0259) were each significantly correlated with ASD risk. These risk factors and their internal relationship with ASD or ASD traits warrant further studies.

Published
2020
Full Text
View/download PDF

2. Early Screening and Risk. Factors of Autism Spectrum Disorder in a Large Cohort of Chinese Patients With Prader-Willi Syndrome.

Author

Kong, Xuejun, Zhu, Junli, Tian, Ruiyi, Liu, Siyu, Sherman, Hannah T., Zhang, Xiaoying, Lin, Xiaojing, Han, Yan, Xiang, Zhi, Koh, Madelyn, Hobbie, Clara, Wang, Bryan, Liu, Kevin, Liu, Jun, Yin, Yueping, and Wan, Guobin

Subjects
CHINESE people, AUTISM spectrum disorders, PRADER-Willi syndrome, SLEEP apnea syndromes
Abstract

Previous studies regarding the prevalence of Autism Spectrum Disorder (ASD) in patients with Prader-Willi Syndrome (PWS) have implicated heterogenous findings. Additionally, the early screening of ASD high-risk population for ASD and identifying ASD risk factors in PWS patients have not been explored. This study included 218 Chinese PWS patients aged 3 months to 18 years old. 78% of subjects were identified as high risk for ASD by ASQ-3 Communication domain score for those younger than 3 years of age and 84% of subjects were classified as high risk for ASD by the GARS-3 for those aged 3 years and older. Among PWS clinical measurements, under-height (P = 0.0186), overweight (P = 0.0248), and obstructive sleep apnea (P = 0.0259) were each significantly correlated with ASD risk. These risk factors and their internal relationship with ASD or ASD traits warrant further studies. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

3. Early Screening and Risk Factors of Autism Spectrum Disorder in a Large Cohort of Chinese Patients With Prader-Willi Syndrome

Author

Xiaoying Zhang, Madelyn Koh, Zhi Xiang, Siyu Liu, Junli Zhu, Yan Han, Xuejun Kong, Jun Liu, Hannah Sherman, Kevin X. Liu, Bryan K. Wang, Yue-Ping Yin, Xiaojing Lin, Clara Hobbie, Ruiyi Tian, and Guobin Wan

Subjects
Pediatrics, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, genetic structures, lcsh:RC435-571, Population, Overweight, behavioral disciplines and activities, 03 medical and health sciences, Autism Spectrum Disorder (ASD), 0302 clinical medicine, lcsh:Psychiatry, mental disorders, medicine, 0501 psychology and cognitive sciences, In patient, education, Original Research, Psychiatry, education.field_of_study, business.industry, 05 social sciences, autism like phenotype (ALP), nutritional and metabolic diseases, weight, medicine.disease, Large cohort, Obstructive sleep apnea, Psychiatry and Mental health, Autism spectrum disorder, Prader-Willi Syndrome (PWS), medicine.symptom, business, 030217 neurology & neurosurgery, 050104 developmental & child psychology, height
Abstract

Previous studies regarding the prevalence of Autism Spectrum Disorder (ASD) in patients with Prader-Willi Syndrome (PWS) have implicated heterogenous findings. Additionally, the early screening of ASD high-risk population for ASD and identifying ASD risk factors in PWS patients have not been explored. This study included 218 Chinese PWS patients aged 3 months to 18 years old. 78% of subjects were identified as high risk for ASD by ASQ-3 Communication domain score for those younger than 3 years of age and 84% of subjects were classified as high risk for ASD by the GARS-3 for those aged 3 years and older. Among PWS clinical measurements, under-height (P = 0.0186), overweight (P = 0.0248), and obstructive sleep apnea (P = 0.0259) were each significantly correlated with ASD risk. These risk factors and their internal relationship with ASD or ASD traits warrant further studies.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results