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3 results on '"antimalarial toxicity"'

1. Chloroquine Cardiotoxicity Leading to Cardiogenic Shock

Author

Madeleine Alder, MD, Richa Gupta, MD, MPH, Giovanni E. Davogustto, MD, Meghan E. Kapp, MD, MS, and JoAnn Lindenfeld, MD

Subjects
acute heart failure, antimalarial toxicity, cardiomyopathy, chronic heart failure, endomyocardial biopsy, systolic heart failure, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

A patient with a history of heart block and longstanding chloroquine use presented in cardiogenic shock refractory to medical therapy and mechanical circulatory support. Autopsy supported antimalarial-induced cardiomyopathy (AMIC). Progression of AMIC may be halted with early recognition and cessation of antimalarial therapy, highlighting importance of screening and timely diagnosis. (Level of Difficulty: Beginner.)

Published
2020
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2. Chloroquine Cardiotoxicity Leading to Cardiogenic Shock

Author

Meghan E. Kapp, Madeleine Alder, JoAnn Lindenfeld, Giovanni Davogustto, and Richa Gupta

Subjects
0301 basic medicine, medicine.medical_specialty, antimalarial toxicity, Heart block, acute heart failure, Cardiomyopathy, Autopsy, 030105 genetics & heredity, 03 medical and health sciences, 0302 clinical medicine, Refractory, Chloroquine, CMR, cardiac magnetic resonance, Internal medicine, LVEF, left ventricular ejection fraction, medicine, Diseases of the circulatory (Cardiovascular) system, LV, left ventricular, Cardiotoxicity, BNP, brain natriuretic peptide, business.industry, Cardiogenic shock, AV, atrioventricular, systolic heart failure, Mini-Focus Issue: Heart Failure, Case Report: Heart Care Team/Multidisciplinary Team Live, medicine.disease, chronic heart failure, RC666-701, Circulatory system, endomyocardial biopsy, Cardiology, EMB, endomyocardial biopsy, AMIC, antimalaria-induced cardiomyopathy, Cardiology and Cardiovascular Medicine, business, AM, antimalarial medication, cardiomyopathy, 030217 neurology & neurosurgery, medicine.drug
Abstract

A patient with a history of heart block and longstanding chloroquine use presented in cardiogenic shock refractory to medical therapy and mechanical circulatory support. Autopsy supported antimalarial-induced cardiomyopathy (AMIC). Progression of AMIC may be halted with early recognition and cessation of antimalarial therapy, highlighting importance of screening and timely diagnosis. (Level of Difficulty: Beginner.), Graphical abstract

Published
2020

3. Chloroquine Cardiotoxicity Leading to Cardiogenic Shock.

Author

Alder M, Gupta R, Davogustto GE, Kapp ME, and Lindenfeld J

Abstract

A patient with a history of heart block and longstanding chloroquine use presented in cardiogenic shock refractory to medical therapy and mechanical circulatory support. Autopsy supported antimalarial-induced cardiomyopathy (AMIC). Progression of AMIC may be halted with early recognition and cessation of antimalarial therapy, highlighting importance of screening and timely diagnosis. ( Level of Difficulty: Beginner. )., Competing Interests: Dr. Lindenfeld has received consulting fees from Abbott, AstraZeneca, Boehringer Ingelheim, CVRx, Impulse Dynamics, Edwards Lifesciences, and V-Wave; and grant support from AstraZeneca. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose., (© 2020 The Authors.)

Published
2020
Full Text
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