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ABSTRACT Introduction Methods Results Conclusion The new ‘WHO Reporting System for Lung Cytopathology’ (2022) includes an ‘Insufficient’/‘Inadequate’/‘Non‐diagnostic’ category. Although they recommend that each laboratory should choose one term to report this diagnostic category, they do not recommend one term over the others. Our aim was to evaluate the use of these three terms in pulmonary FNACs among Spanish pathologists.A web‐based survey among Spanish pathologists using Google Forms was performed. It included 14 yes/no and multiple‐choice questions, the latter with an open‐text option where it was possible to give a different answer from the ones given. Some questions inquired about their daily practice routine whilst others proposed different cytological examples with the intention of knowing how they would report those particular cases.Twenty‐eight participants (18 cytopathologists, two general pathologists and seven residents) from 17 different Spanish hospitals completed the survey. Most of the respondents use more than one term of this diagnostic category, and there is a lack of reproducibility on the criteria to use one specific term.There is a need to clearly define this category to reduce variability between pathologists. [ABSTRACT FROM AUTHOR]

Background/Objectives: This study evaluated the appropriateness of transmucosal immediate-release fentanyl (TIRF) prescriptions in a Madrid emergency room during 2019 and 2022, following a 2018 warning about off-label use. Methods: TIRF prescription in the emergency room search yielded 993 patients in 2019 and 1499 in 2022, of which 140 were randomized for the study, 70 in 2019, and 70 in 2022. Dose appropriateness and indication for TIRF were analyzed according to established criteria. Results: Despite a high prevalence of cancer diagnoses (77.9%, 109/140), only 32.9% (46/140) of patients met the appropriateness criteria pre-hospitalization. This improved to 42.5% (51/120) at discharge, but the change was not statistically significant overall. However, focusing on surviving patients reveals a significant improvement in appropriateness, increasing from 30.83% (37/120) to 42.50% (p = 0.002). This improvement was particularly pronounced in 2022 (p = 0.0269), but not in 2019 (p = 0.0771). Interestingly, appropriateness in patients with prior TIRF prescriptions remained relatively stable from pre-hospitalization (46.75%) to discharge (48.78%). A concerningly high proportion of patients with cancer diagnoses (68.75%) received low-dose opioid therapy (<60 MME) at discharge, and 36.8% of patients over 80 years old were co-prescribed benzodiazepines, contradicting prescribing guidelines. Conclusions: This study found inappropriate TIRF prescriptions were common in an emergency room setting, often due to low pre-hospital opioid doses. While hospitalization improved TIRF appropriateness in survivors, especially in 2022, concerning prescribing practices persisted. This emphasizes the need for better education and interventions to ensure safe and effective TIRF use. [ABSTRACT FROM AUTHOR]

Hospital-acquired bloodstream infections (HA-BSI) in the intensive care unit (ICU) are common life-threatening events. We aimed to investigate the association between early adequate antibiotic therapy and 28-day mortality in ICU patients who survived at least 1 day after the onset of HA-BSI. We used individual data from a prospective, observational, multicentre, and intercontinental cohort study (Eurobact2). We included patients who were followed for ≥1 day and for whom time-to-appropriate treatment was available. We used an adjusted frailty Cox proportional-hazard model to assess the effect of time-to-treatment-adequacy on 28-day mortality. Infection- and patient-related variables identified as confounders by the Directed Acyclic Graph were used for adjustment. Adequate therapy within 24 hours was used for the primary analysis. Secondary analyses were performed for adequate therapy within 48 and 72 hours and for identified patient subgroups. Among the 2418 patients included in 330 centres worldwide, 28-day mortality was 32.8% (n = 402/1226) in patients who were adequately treated within 24 hours after HA-BSI onset and 40% (n = 477/1192) in inadequately treated patients (p < 0.01). Adequacy within 24 hours was more common in young, immunosuppressed patients, and with HA-BSI due to Gram-negative pathogens. Antimicrobial adequacy was significantly associated with 28-day survival (adjusted Hazard Ratio (aHR), 0.83; 95% CI, 0.72–0.96; p 0.01). The estimated population attributable fraction of 28-day mortality of inadequate therapy was 9.15% (95% CI, 1.9–16.2%). In patients with HA-BSI admitted to the ICU, the population attributable fraction of 28-day mortality of inadequate therapy within 24 hours was 9.15%. This estimate should be used when hypothesizing the possible benefit of any intervention aiming at reducing the time-to-appropriate antimicrobial therapy in HA-BSI. [ABSTRACT FROM AUTHOR]

Around three million pensioners receive the Indonesian civil service pension benefit. This benefit is the main source of income for the majority of civil service pensioners. This paper examines the adequacy of this pension benefit from the perspective of pensioners in Kapuas Regency. Through qualitative research, fifteen semi-structured interviews were conducted to investigate the role of pension benefits in maintaining the interviewees' lifestyles and standards of living. All the interviewees perceived that the pension benefit could cover their basic needs, but for most of them, it only covered 25% of their total expenditures. Despite this, the replacement rate of the take-home pay from the pension benefit is still acceptable based on the ILO standard. While some can adjust to life with basic needs, others choose to find another source of income after retirement. Therefore, although the amount is still higher than the poverty line and the minimum wage, the findings suggest the retirement rate is considered meager. [ABSTRACT FROM AUTHOR]

Background: The aim of this study is to evaluate the distribution of the histological results of the endocervical curettage (ECC) at large loop excision of the transformation zone (LLETZ) as well as the additional diagnostic information and its impact on further clinical treatment recommendations in accordance with national guidelines. The ECC in addition to LLETZ can serve to detect (pre)cancerogenic lesions above the endocervical cone margin, although its predictive value as well as diagnostic accuracy remains vague due to limited studies performed on this topic. Methods: In this retrospective cohort study, 1121 patients who underwent LLETZ and concomitant ECC during a twelve-year period (2009–2021) were analyzed. The main outcome parameters were the histological diagnosis and incidence of adequate or inadequate ECC specimens. Results: In 1.7% of the specimens, ECC performed at the completion of LLETZ yielded additional diagnostic information. The histological result of the ECC had an impact on subsequent therapeutic approach in 2 of the 1121 patients (0.2%). Furthermore, a negative ECC yielded a low negative predictive value (NPV) of 43.8% for the detection of residual disease. Conclusions: As current guidelines increasingly support the performance of an HPV test six months after LLETZ as an indicator of treatment success irrespective of the margin status, the routine performance of an ECC at LLETZ remains questionable. [ABSTRACT FROM AUTHOR]

Background: Autopsies are done since the olden days to study anatomy, to learn pathology, and to identify the cause of death. However, this procedure is not widely accepted due to lack of facilities, reluctancies by relatives, various religious and ethical issues, and fear of transmission of communicable diseases. Percutaneous needle autopsies have bridged these shortcomings and provide better results when done under radiological guidance. Aims and Objectives: The aim of the study was to determine the adequacy of tissue obtained by percutaneous needle autopsy in comparison to conventional autopsy for lung and liver tissues. Materials and Methods: Descriptive study, done in autopsies performed in the Department of Forensic Medicine and Department of Pathology, Government Medical College Kottayam. Percutaneous needle samples are obtained from lungs and liver using surface landmarks. Samples are also obtained after opening the deceased body. After microscopic examination, adequacy is observed and morphological findings are compared. Results: In lungs, 164 samples met the adequacy criteria and 156 samples showed similar morphological findings by both methods; in the liver 159 samples met the adequacy criteria and 151 samples showed similar morphological findings by both methods. In lungs and liver, the most common histological finding was congestion. Conclusion: Percutaneous needle autopsies and the tissue thus obtained are adequate and comparable when compared to conventional autopsies. The findings are more comparable in diffuse lesions rather than in localized lesions. [ABSTRACT FROM AUTHOR]

Purpose: The identification of patients with chronic hypoparathyroidism who are adequately (AC) or not adequately controlled (NAC) has clinical interest, since poor disease control is related to complications and mortality. We aimed to assess the prevalence of NAC patients in a cohort of subjects with postsurgical hypoparathyroidism. Methods: We performed a multicenter, retrospective, cohort study including patients from 16 Spanish hospitals with chronic hypoparathyroidism lasting ≥3 years. We analyzed disease control including biochemical profile and clinical wellness. For biochemical assessment we considered three criteria: criterion 1, normal serum calcium, phosphorus and calcium x phosphorus product; criterion 2, the above plus estimated glomerular filtration rate ≥60 ml/min/1.73 m2 ; and criterion 3, the above plus normal 24-hour urinary calcium excretion. A patient was considered AC if he or she met the biochemical criteria and was clinically well. Results: We included 337 patients with postsurgical hypoparathyroidism (84.3% women, median age 45[36-56] years, median time of follow-up 8.9[6.0-13.0] years). The proportions of NAC patients with criteria 1, 2 and 3 were, respectively, 45.9%, 49.2% and 63.1%. Patients who had dyslipidemia at the time of diagnosis presented a significantly higher risk of NAC disease (criterion 3; OR 7.05[1.44- 34.45]; P=0.016). NAC patients (criterion 2) had a higher proportion of subjects with incident chronic kidney disease and eye disorders, and NAC patients (criterion 3) had a higher proportion of incident chronic kidney disease, nephrolithiasis and dyslipidemia than AC patients. Conclusion: The present study shows a strikingly high prevalence of NAC patients in the clinical practice of Spanish endocrinologists. Results suggest that NAC disease might be associated with some prevalent and incident comorbidities. [ABSTRACT FROM AUTHOR]

Spinoza’s epistemology aims at the development of “adequate” and the removal of “confused” ideas. Spinoza’s theory of confusion raises many questions, however. It has often been thought that the confusion of an idea is mind-relative, such that an idea might be confused in my mind but adequate in God’s. In this paper I argue that confusion cannot be mind-relative, because an idea’s confusion is determined by what it represents and for Spinoza, ideas are individuated by their representational content. Instead, I propose that although it is possible to consider one and the same idea both adequately and confusedly, what such considerings pick up on are mind-independent features of ideas.

We give a domain-theoretic semantics to a statistical programming language, using the plain old category of dcpos, in contrast to some more sophisticated recent proposals. Remarkably, our monad of minimal valuations is commutative, which allows for program transformations that permute the order of independent random draws, as one would expect. A similar property is not known for Jones and Plotkin's monad of continuous valuations. Instead of working with true real numbers, we work with exact real arithmetic, providing a bridge towards possible implementations (implementations by themselves are not addressed here). Rather remarkably, we show that restricting ourselves to minimal valuations does not restrict us much: All measures on the real line can be modeled by minimal valuations on the domain IR⊥ of exact real arithmetic. We give three operational semantics for our language, and we show that they are all adequate with respect to the denotational semantics. We also explore quite a few examples to demonstrate that our semantics computes exactly as one would expect and to debunk the myth that a semantics based on continuous maps would not be expressive enough to encode measures with non-compact support using only measures with compact support, or to encode measures via non-continuous density functions, for instance. Our examples also include some useful, non-trivial cases of distributions on higher-order objects. [ABSTRACT FROM AUTHOR]

Abstract Background Inadequacy of antenatal care (ANC) utilization is a prominent public health problem, causing poor pregnancy outcomes. In developing countries, including Ethiopia, having ANC coverage, many pregnant women do not achieve the first ANC visits in the first trimester and receive at least four ANC visits. Therefore, this study aimed to examine the magnitude and identify determinants of inadequacy of antenatal care attendance amongst pregnant women in Ethiopia. Methods Inadequate ANC attendance was defined as combining starting ANC visits after the first trimester and having fewer than four visits together. The study used secondary data from the 2019 mini-demographic and health survey. A weighted sample of 3927 pregnant women was included in this study. Data management and further analysis were performed using STATA 14 software. A multivariable generalized estimating equation analysis was used to identify determinants associated with inadequacy of antenatal care attendance. The Adjusted odds ratio with a 95% confidence interval was used to identify significant variables for inadequate antenatal care visits. Result Overall, 78.5% of pregnant women did not attend adequate antenatal care visits during pregnancy. In multivariable generalized estimating equation analysis, women aged 25 to 34 years (AOR = 0.77, 95% CI: 0.61–0.95), being educated (AOR = 0.31; 95% CI: 0.22–0.45), and being wealthier index (AOR = 0.67, 95% CI: 0.51–0.88) were less likely to inadequate antenatal care attendance. Whereas being rural residents (AOR = 1.49; 95% CI:1.08–2.07), no television exposure (AOR = 1.51; 95% CI:1.1–2.06), having more family members in the household (AOR = 1.81; 95% CI: 1.11–2.95), and women from semi-peripheral region (AOR = 1.92; 95% CI: 1.42–2.59) were higher odds of being associated with inadequacy of antenatal care attendance. Conclusions The prevalence of Inadequate antenatal care attendance amongst pregnant women in Ethiopia is still High. The study identifies significant variables that could be positively and negatively associated with inadequate antenatal care visits. Health education interventions should target uneducated, poorer, and rural women to attend early antenatal care and use at least four antenatal care utilization for early detection of complications during pregnancy and delivery.

Abstract Background Antenatal care (ANC) is an important component in the continuum of care. Providing adequate quality ANC is necessary to prevent maternal and newborn mortality. The coverage of ANC has increased significantly in the last decade in India, but a mere increase in coverage is insufficient if the issue of quality is not simultaneously addressed. This study examines the change in each component of quality ANC between 2015-16 and 2019-21, highlights the factors associated with adequate quality ANC, and observes the state- and district-level distribution of adequate quality ANC during 2019-21. Methods This study is based on data from the two most recent rounds of the National Family Health Survey (NFHS), the Indian equivalent of the Demographic and Health Surveys (DHS). These rounds were conducted in 2015-16 and 2019-21 in selected households of India with a total of 190,797 and 176,843 sampled births, respectively. The dependent variable was quality antenatal care, a composite variable consisting of skilled healthcare providers, timeliness, sufficiency, and appropriateness of content. The independent variables were mother’s age, education, wealth quintile, birth order, mass media exposure, health insurance coverage, relationship with the head of household, facility exposure, intended pregnancy, history of adverse pregnancy outcomes, and other socio-demographic variables. Change in each component and dimension of quality antenatal care was assessed using data from both rounds of the survey. A multivariate multinomial logistic regression analysis was employed to identify the determinants of adequate quality ANC using the NFHS-5 data. Results The findings revealed that 32 per cent of mothers received adequate quality antenatal care in 2019–2021, an increase of only 9% points compared to the 2015-16 period. Two significant barriers to achieving adequate quality antenatal care, in terms of appropriateness of content, were the provision of Iron and Folic Acid (IFA) tablets and counselling. The highest utilisation of adequate quality antenatal care was observed in the southern states. The utilisation of quality ANC increased with an increase in women’s education and wealth status; and was more prevalent among those with health insurance coverage and exposure to mass media. Conclusion Despite some improvements in the coverage of antenatal care, the quality of antenatal care continues to be very low and needs urgent attention. Achieving quality antenatal care in both content and experience requires addressing service gaps and developing better measures to capture and improve women’s care experiences.

The article examines the features of literary translations of A.S. Pushkin's poems into the Kyrgyz language, authored by the People's Poet of the Kyrgyz Republic Omor Sultanov. The problem of the research lies in the lack of knowledge of the originality and stages of development of literary translations into the Kyrgyz language of the works of even the most famous Russian poets. The object of the study is literary translations of Pushkin’s poems into the Kyrgyz language, carried out by O. Sultanov. The subject of the research is the characteristics of equivalence, freedom and adequacy of the literary translations being studied. The novelty and scientific value of this study lies in the fact that it is based on a theoretical and practical approach. In the work, by line-by-line comparison of the originals and Kyrgyz translations of specific poems, the main nuances, criteria and artistic circumstances of their similarities or differences are determined. The interaction of unrelated languages, Russian and Kyrgyz, within the framework of literary translation is studied. It seems very relevant to trace their mutual influence in the context of the ongoing integration processes between Russia and Kyrgyzstan, including in the sphere of culture. In this case, the study of literary translations of poetry by Pushkin as the most popular Russian-language poet is quite understandable. Literary translations of his poems into the Kyrgyz language in O. Sultanov’s version have elements of the necessary equivalence, freedom and adequacy.

Background: Antenatal care (ANC) is an important component in the continuum of care. Providing adequate quality ANC is necessary to prevent maternal and newborn mortality. The coverage of ANC has increased significantly in the last decade in India, but a mere increase in coverage is insufficient if the issue of quality is not simultaneously addressed. This study examines the change in each component of quality ANC between 2015-16 and 2019-21, highlights the factors associated with adequate quality ANC, and observes the state- and district-level distribution of adequate quality ANC during 2019-21. Methods: This study is based on data from the two most recent rounds of the National Family Health Survey (NFHS), the Indian equivalent of the Demographic and Health Surveys (DHS). These rounds were conducted in 2015-16 and 2019-21 in selected households of India with a total of 190,797 and 176,843 sampled births, respectively. The dependent variable was quality antenatal care, a composite variable consisting of skilled healthcare providers, timeliness, sufficiency, and appropriateness of content. The independent variables were mother's age, education, wealth quintile, birth order, mass media exposure, health insurance coverage, relationship with the head of household, facility exposure, intended pregnancy, history of adverse pregnancy outcomes, and other socio-demographic variables. Change in each component and dimension of quality antenatal care was assessed using data from both rounds of the survey. A multivariate multinomial logistic regression analysis was employed to identify the determinants of adequate quality ANC using the NFHS-5 data. Results: The findings revealed that 32 per cent of mothers received adequate quality antenatal care in 2019–2021, an increase of only 9% points compared to the 2015-16 period. Two significant barriers to achieving adequate quality antenatal care, in terms of appropriateness of content, were the provision of Iron and Folic Acid (IFA) tablets and counselling. The highest utilisation of adequate quality antenatal care was observed in the southern states. The utilisation of quality ANC increased with an increase in women's education and wealth status; and was more prevalent among those with health insurance coverage and exposure to mass media. Conclusion: Despite some improvements in the coverage of antenatal care, the quality of antenatal care continues to be very low and needs urgent attention. Achieving quality antenatal care in both content and experience requires addressing service gaps and developing better measures to capture and improve women's care experiences. [ABSTRACT FROM AUTHOR]

Background: Inadequacy of antenatal care (ANC) utilization is a prominent public health problem, causing poor pregnancy outcomes. In developing countries, including Ethiopia, having ANC coverage, many pregnant women do not achieve the first ANC visits in the first trimester and receive at least four ANC visits. Therefore, this study aimed to examine the magnitude and identify determinants of inadequacy of antenatal care attendance amongst pregnant women in Ethiopia. Methods: Inadequate ANC attendance was defined as combining starting ANC visits after the first trimester and having fewer than four visits together. The study used secondary data from the 2019 mini-demographic and health survey. A weighted sample of 3927 pregnant women was included in this study. Data management and further analysis were performed using STATA 14 software. A multivariable generalized estimating equation analysis was used to identify determinants associated with inadequacy of antenatal care attendance. The Adjusted odds ratio with a 95% confidence interval was used to identify significant variables for inadequate antenatal care visits. Result: Overall, 78.5% of pregnant women did not attend adequate antenatal care visits during pregnancy. In multivariable generalized estimating equation analysis, women aged 25 to 34 years (AOR = 0.77, 95% CI: 0.61–0.95), being educated (AOR = 0.31; 95% CI: 0.22–0.45), and being wealthier index (AOR = 0.67, 95% CI: 0.51–0.88) were less likely to inadequate antenatal care attendance. Whereas being rural residents (AOR = 1.49; 95% CI:1.08–2.07), no television exposure (AOR = 1.51; 95% CI:1.1–2.06), having more family members in the household (AOR = 1.81; 95% CI: 1.11–2.95), and women from semi-peripheral region (AOR = 1.92; 95% CI: 1.42–2.59) were higher odds of being associated with inadequacy of antenatal care attendance. Conclusions: The prevalence of Inadequate antenatal care attendance amongst pregnant women in Ethiopia is still High. The study identifies significant variables that could be positively and negatively associated with inadequate antenatal care visits. Health education interventions should target uneducated, poorer, and rural women to attend early antenatal care and use at least four antenatal care utilization for early detection of complications during pregnancy and delivery. [ABSTRACT FROM AUTHOR]

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In the Cratylus, Plato addresses the question of the orthótes onomáton, the “accuracy” or “adequacy” of names regarding what they would name. Two positions come into play regarding such adequacy (the conventionalism of Hermogenes and the naturalism of Cratylus), both of which are dismantled by the Platonic Socrates. But only two? Isn’t there in the Cratylus at least an indication of a possible Platonic “adequacy”? This paper presents that possible “adequacy”. For this, the difference between name (or “natural” name) and word is discussed, as well as the need to anchor designation in essences; above all, it is shown that it is necessary to consider the question of name in relation to that of logos. For that purpose, an interpretation of the Cratylus is articulated with some passages from the Phaedo and the Sophist. [ABSTRACT FROM AUTHOR]

Previous studies suggest that the adequacy rate of thyroid aspirates can be improved by altering the adequacy criteria of the Bethesda System. We sought to measure the performance of these altered criteria in a prospective fashion. Over a 6-year period, cases with 1 to 59 follicular cells were prospectively classified as "nondiagnostic, favor benign" or "scant but adequate". "Scant but adequate" cases were classified as either benign (Bethesda category 2) or atypia of undetermined significance (AUS) (Bethesda category 3). Bethesda category 3 cases were referred for Afirma testing (Veracyte, San Francisco, CA). Of 5147 cases, 131 (3%) were classified as "nondiagnostic, favor benign"; 45 (65%) of these had follow-up with a risk of malignancy of 2.6%. Additionally, 436 (8%) of all 5147 cases were classified as "scant but adequate" and "benign"; 49 (11%) of these had follow-up with a risk of malignancy of 0%. Lastly, 197 (4%) of all 5147 cases were classified as "scant but adequate" with AUS; 177 (90%) of these 197 cases had an adequate Afirma result. The "suspicious" rate was not significantly different than that of cases classified as "adequate" and AUS (Bethesda category 3 and 4) (35 of 197 [18%] versus 140 of 848 [17%] P = 0.67), and there was no significant difference in the risk of malignancy for these 2 categories ("scant but adequate" 9 of 18, "adequate" 50% versus 27 of 85, 32%, P = 0.10). Overall, the modified Bethesda criteria reduced the nondiagnostic rate from 22% to 10% (P <0.001) without lowering the sensitivity of the test. Modified Bethesda adequacy criteria can significantly lower nondiagnostic rates without lowering sensitivity. • Precis: Modified Bethesda adequacy criteria can significantly lower nondiagnostic rates without decreasing sensitivity. [ABSTRACT FROM AUTHOR]

One of the most important legal issues concerning gender identity is ensuring that no one is discriminated against in any type of environment and that individuals' needs are considered seriously during the legislation process. Even though this can be questioned, if one needs to process information on gender to achieve an inclusive and diverse society and law, it seems that at this point in the history of society, there are no better measures to ensure a non-discriminatory environment than processing information on gender identity. Under the current personal data protection landscape, both in the European Union and the United States, it is not clear what the conditions are for processing information on the gender of individuals. Therefore, the authors of this article analyse legal requirements from both jurisdictions, also in the light of the question of the adequacy of personal data protection in the US under article 45 of the General Data Protection Regulation. [ABSTRACT FROM AUTHOR]

This study investigated the information needs of prisoners and the adequacy of information resources in prison libraries in Anambra State, Nigeria. Two research questions guided the study. The population of the study was 1781 inmates in prisons in Anambra State. The sample size of 327 was selected using Taro Yamane’s formula and proportionate stratified sampling techniques. Two instruments titled the Information Needs of Prisoners Questionnaire and the Adequacy of Information Resources Checklist were used for data collection. The instruments were validated by three experienced lecturers. One in the department of Educational Foundations (Measurement and Evaluation Unit) and two in the Department of Library and Information Science, all at Nnamdi Azikiwe University, Awka. Cronbach's alpha was used to determine the internal consistency of the questionnaire items, with a value of 0.79. The researchers administered the questionnaires with the help of four research assistants (correctional officers). Out of 327 questionnaires administered, 314 were successfully retrieved. The percentage return rate of distributed questionnaires is 96%. Data collected were analyzed using descriptive statistics of the mean; also, the International Federation of Library Association (IFLA) guideline for library services to prisoners was also used as a yardstick for the measurement of adequacy. The results from the data analysis indicated that prisoners have diverse information needs that, when met, would help them during their stay in prison as well as when they are eventually released; these needs include legal information, information on prison rules, financial information, and others. While there were few information resources found to be adequate, the inadequacy of most of the listed information resources is recorded in prison libraries in Anambra State, Nigeria. It is therefore recommended that information resources be made adequately available for prisoners in relation to their information needs. [ABSTRACT FROM AUTHOR]

Translating the Holy Quran into different languages is a crucial task. It is a daunting one, given the linguistic complexity and rich cultural context of this holy scripture. The recent advancements in technology, especially in artificial intelligence, brought about a pressing need to explore the potential of machine learning-based tools in easing the translation of religious texts, the Holy Quran in particular. This study explores the potential of adopting ChatGPT, a large language model (LLM) powered by machine learning, in English Quranic translation. The study aims to assess the accuracy, adequacy, and cultural sensitivity of ChatGPT's English Quranic translation and identify potential challenges and limitations of using this tool in this domain. The study employed a comparative analysis approach, evaluating ChatGPT's translation of the El Fatiha Chapter against five humangenerated translations using BLEU (Bilingual Evaluation Understudy) and METEOR (Metric for Evaluation of Translation with Explicit ORdering) machine translation metrics. The study also utilized an interpretation of the chapter by El Qurtubi to ensure that ChatGPT has the entire linguistic and cultural context of the chapter. The study's findings indicated that ChatGPT's English translation of El Fatiha achieved a moderate level of accuracy and adequacy with mean BLEU and METEOR scores of 0,48 and 0,78, respectively. However, there were areas where ChatGPT's translation could be improved. The use of ML-based tools such as ChatGPT in English Quranic translation offers promising benefits as it can aid translators in the translation process. [ABSTRACT FROM AUTHOR]

Introduction: Shankhaprakshalana (SP) is a yogic method aiming to cleanse the bowel. It involves the use of warm saline water and a combination of five asanas. This study was designed to assess the effectiveness and safety of bowel preparation by SP. Methods: This is a retrospective observational study of prospectively collected data. Patients planned for colonoscopy were screened and enrolled to undergo bowel preparation by SP on the day of the colonoscopy. Patients having comorbid conditions, poor performance status, suspected or previously diagnosed intestinal stricture and past history of major abdominal surgery and those unable to perform asanas of SP were excluded. A low-fiber diet was advised for one day before the colonoscopy. Patients were advised to drink 400 mL of lukewarm saline water followed by five asanas (exercises) of SP, each done eight times dynamically and sequentially. After completing six such cycles, patients underwent colonoscopy. Boston Bowel Preparation Scale (BBPS) score was used to assess the quality of bowel preparation. Results: Total 238 patients were included. The major indications for colonoscopy were abdominal pain (35.3%), hematochezia (23.9%), diarrhea (20.2%), constipation (10.9%) and anemia (9.7%). The mean age was 37.7 (± 12) years. The mean BBPS was 8 (± 1.2). Bowel preparation was inadequate (BBPS < 6) in only two patients. Mean segmental BBPS for the three segments of the colon (right, transverse and left) was 2.6 (± 0.5), 2.7 (± 0.4) and 2.6 (± 0.7), respectively. Minor adverse events (nausea, abdominal pain, vomiting, giddiness and bloating) were noted in 10 participants (4.2%), which did not require hospitalization. Bowel preparation was completed in 133 (± 35) minutes. Conclusion: Shankhaprakshalana is an effective and safe method to achieve adequate bowel preparation before colonoscopy. Since this is a single-center and retrospective study, future multi-centric, prospective studies comparing it with the standard bowel preparation regimens are warranted. [ABSTRACT FROM AUTHOR]

Biomedical scientists (BMS) can report sample adequacy during EBUS TBNA using rapid on-site evaluation (ROSE). Despite being able to report exfoliative samples such as pleural fluid cytology and bronchial washings, they are usually not permitted to offer a preliminary diagnostic impression of EBUS TBNA samples. Experienced biomedical scientists can provide a reliable diagnostic impression during ROSE for EBUS samples, with sensitivity and specificity comparable to cytopathologist reporting. This work represents an advance in biomedical science because it provides evidence a BMS can safely and accurately provide a real time cytopathological impression from EBUS TBNA sampling, which could positively impact patient pathways.

Resumen: En los últimos años se ha modificado el significado de adecuación en diálisis peritoneal. Hemos asistido a una transición desde un concepto de adecuación enfocado esencialmente a la obtención de unos objetivos en determinados parámetros —aclaramiento de solutos y ultrafiltración— a una aproximación más holística centrada en la calidad de vida del paciente. El propósito de este documento es proporcionar a sus destinatarios recomendaciones, actualizadas y centradas en nuestro entorno sociosanitario, para la adecuación y la prescripción de la diálisis peritoneal. El documento se ha estructurado en tres grandes apartados: adecuación, función renal residual y prescripción en diálisis peritoneal continua ambulatoria y diálisis peritoneal automática. Recientemente se ha publicado una guía sobre el mismo tema, elaborada por un Comité de Expertos de la Sociedad Internacional de Diálisis Peritoneal (ISPD) (2020). En consideración a las aportaciones del grupo de expertos de la ISPD y a la cuasi simultaneidad de los dos proyectos se hacen referencias a esta guía en los apartados pertinentes. Se ha seguido una metodología sistemática (GRADE), que especifica el nivel de evidencia y la fuerza de las sugerencias y recomendaciones propuestas, y facilita actualizaciones futuras de la guía. Abstract: In recent years, the meaning of adequacy in peritoneal dialysis has changed. We have witnessed a transition from an exclusive achievement of specific objectives —namely solute clearances and ultrafiltration— to a more holistic approach more focused to on the quality of life of these patients. The purpose of this document is to provide recommendations, updated and oriented to social and health environment, for the adequacy and prescription of peritoneal dialysis. The document has been divided into three main sections: adequacy, residual kidney function and prescription of continuous ambulatory peritoneal dialysis and automated peritoneal dialysis. Recently, a guide on the same topic has been published by a Committee of Experts of the International Society of Peritoneal Dialysis (ISPD 2020). In consideration of the contributions of the group of experts and the quasi-simultaneity of the two projects, references are made to this guide in the relevant sections. We have used a systematic methodology (GRADE), which specifies the level of evidence and the strength of the proposed suggestions and recommendations, facilitating future updates of the document.

Introduction. Transport and technological means based on tracked undercarriages have found their use in both military and civilian industries. Their widespread use is due to a number of advantages that contribute to the further development of mechanization of production, increasing the efficiency of transportation of minerals, and developing infrastructure during the development of new territories. Ensuring cross-country ability and mobility of vehicles with tracked undercarriages, including tracked conveyor-tractors, is possible through the use of hybrid electromechanical transmissions. One of the components of scientific research in this direction is carrying out simulation modeling of the movement of equipment. Modeling the motion process will make it possible to substantiate the energy characteristics of the electromechanical transmission of a tracked vehicle and confirm the adequacy of previously performed theoretical studies.Research methods. The main objective of the simulation was to confirm the effectiveness of the theoretical studies performed. The studies in the VISSIM programming environment using typical motion cycles that equivalently reflect the operating conditions and use of a tracked machine were carried out.Results. As a result of the research, quantitative estimates of the influence of the power of a diesel generator and the charge of an energy storage device on the dynamic performance of equipment were obtained. It has been established that in order to meet the requirements for promising samples, the power of the energy storage device should be at least 2.5 kWh when using a standard internal combustion engine.Discussion and conclusion. The research results can be used to create, based on the existing scientific and technical background, a promising robotic complex with an electromechanical transmission.

Social relationships have been and are the basis for achieving objectives of all kinds, whether altruistic or lucrative. Among the aspects that make up non-verbal communication are physical appearance in general, clothing, and, in particular, colour combinations. In this article, we analyse whether colour combinations can be established in individuals' clothing that maximise their chances of success for a specifically established social objective. To measure this objective, we use multivalent logics, which are characterised by their great flexibility and adaptability. Within the framework of fuzzy logic, we extract evaluations for various colours based on the judgements of experts, provided by recognised authors in the literature, and compare these with the results obtained in a survey conducted by the authors. For the purposes of contrast, we employ two instruments with accredited validity: Similarity by Direct Computation (SDC) and the Technique for Order Performance by Similarity to Ideal Solution (TOPSIS multicriteria method). [ABSTRACT FROM AUTHOR]

Background Patients with kidney failure treated with maintenance haemodialysis (HD) require appropriate small molecule clearance. Historically, a component of measuring 'dialysis adequacy' has been quantified using urea kinetic modelling that is dependent on the HD prescription. However, the impact of dialysate flow rate on urea clearance remains poorly described in vivo and its influence on other patient-important outcomes of adequacy is uncertain. Methods We searched Embase, MEDLINE and the Cochrane Library from inception until April 2022 for randomized controlled trials and observational trials comparing a higher dialysate flow rate (800 ml/min) and lower dialysate flow rate (300 ml/min) with a standard dialysis flow rate (500 ml/min) in adults (age ≥18 years) treated with maintenance HD (>90 consecutive days). We conducted a random effects meta-analysis to estimate the pooled mean difference in dialysis adequacy as measured by Kt/V or urea reduction ratio (URR). Results A total of 3118 studies were identified. Of those, nine met eligibility criteria and four were included in the meta-analysis. A higher dialysate flow rate (800 ml/min) increased single-pool Kt/V by 0.08 [95% confidence interval (CI) 0.05–0.10, P  < .00001] and URR by 3.38 (95% CI 1.97–4.78, P  < .00001) compared with a dialysate flow rate of 500 ml/min. Clinically relevant outcomes including symptoms, cognition, physical function and mortality were lacking and studies were generally at a moderate risk of bias due to issues with randomization sequence generation, allocation concealment and blinding. Conclusion A higher dialysate flow increased urea-based markers of dialysis adequacy. Additional high-quality research is needed to determine the clinical, economic and environmental impacts of higher dialysate flow rates. [ABSTRACT FROM AUTHOR]

This article reports on an empirical study on cognitive processes [i.e. (dis) fluency, temporal management of the translation process, and revision] and their relationship with fluency and adequacy. Based on Jakobsen and Schou's (1999) computational model of human translation, the author utilizes keylogging data retrieved from a Translog-II-based task to investigate the cognitive processes behind Arab translator trainees' translations of an English news article into Arabic and unfold whether these processes predict fluency and adequacy (N = 32). Results demonstrate trainees' segmentation of a news article into frequent short lexical segments manifested in the mean translation units (M = 141.34, SD = 44.37), reliance on online revision over end revision, and temporal delay in the drafting stage. Multiple-line regression analysis shows that translation quality is predicted by revision time, orientation time, and translation speed in addition to a positive association between translation units and translation adequacy. According to the findings, translation trainees should be equipped with ST comprehension, and TT production and revision skills. [ABSTRACT FROM AUTHOR]

In recent decades, disappointing poverty trends and welfare state limitations in many European countries – including constraints on minimum income benefits – have paved the way for a larger role of the third sector. An interesting but controversial form of third-sector in-kind support is food aid provision. In Europe, food aid is, so far, a non-rights-based practice displaying worrisome discretionary and stigmatizing characteristics. Yet, the phenomenon of food aid in Europe has spread, professionalized, and penetrated the institutions of the welfare state. This raises the question if, how and to what extent food aid plays a role in bypassing structural constraints on minimum income protection. This article applies an exploratory case study approach to estimate the monetary value of food aid in relation to statutory minimum incomes in four EU-countries. We use cross-nationally comparable food reference budgets to price food aid packages in Belgium, Finland, Hungary and Spain. The results show that food aid, although not sufficient to close the at-risk-of-poverty gap, is non-trivial for some European households. In Spain and Belgium food aid packages can reach up to €100 a month (expressing 7% to 11% of respective minimum income benefit levels). Importantly, we perceive (formalized) cooperation and interaction between local welfare agencies and food charities in all countries, suggesting that welfare state actors use non-rights-based food aid for filling gaps in the social safety net. The large between- and within-country variation of the monetary values of food aid packages points, however, to food aid as a problematic discretionary practice. [ABSTRACT FROM AUTHOR]

Copyright of Bulletin of Ablai Khan KazUIRandWL: Series 'Philological sciences' is the property of Kazakh Ablai Khan University of International Relations & World Languages and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: The efficacy of endoscopic ultrasound-guided liver biopsy (EUS-LB) compared to percutaneous liver biopsy (PC-LB) remains uncertain. Methods: Our data consist of randomized controlled trials (RCTs) comparing EUS-LB to PC-LB, found through a literature search via PubMed/Medline and Embase. The primary outcome was sample adequacy, whereas secondary outcomes were longest and total lengths of tissue specimens, diagnostic accuracy, and number of complete portal tracts (CPTs). Results: Sample adequacy did not significantly differ between EUS-LB and PC-LB (risk ratio [RR] 1.18; 95% confidence interval [CI] 0.58–2.38; p = 0.65), with very low evidence quality and inadequate sample size as per trial sequential analysis (TSA). The two techniques were equivalent with respect to diagnostic accuracy (RR: 1; CI: 0.95–1.05; p = 0.88), mean number of complete portal tracts (mean difference: 2.29, −4.08 to 8.66; p = 0.48), and total specimen length (mean difference: −0.51, −20.92 to 19.9; p = 0.96). The mean maximum specimen length was significantly longer in the PC-LB group (mean difference: −3.11, −5.51 to −0.71; p = 0.01), and TSA showed that the required information size was reached. Conclusion: EUS-LB and PC-LB are comparable in terms of diagnostic performance although PC-LB provides longer non-fragmented specimens. [ABSTRACT FROM AUTHOR]

Background: Often marginalized and disadvantaged by systems of oppression, Indigenous populations commonly face significant barriers to accessing adequate antenatal care (ANC). The COVID‐19 pandemic had an unprecedented impact on healthcare systems worldwide, including on the provision of antenatal care; this was especially so for Indigenous communities in many regions. As such, our study aimed to estimate the association between the COVID‐19 pandemic and adequate ANC received by Indigenous women in Chiapas, Mexico. Methods: We conducted a retrospective crossover analysis with data collected between June and December 2021 from Indigenous women who attended at least one ANC appointment at one of two health centers in San Cristóbal de las Casas, Chiapas. We used a multinomial logistic regression model considering the time frame (before and during the pandemic) as the primary independent variable. Adequate antenatal care comprised four dimensions: attendance by qualified personnel, timely first visit, sufficient frequency of visits, and adequacy of the content provided during the visits. Results: During the COVID‐19 pandemic, there was a significant drop in ANC adequacy, with 12.7% (95% CI: 8.3, 18.9) of Indigenous women receiving ANC, compared with the pre‐pandemic rate of 52.5% (95% CI: 44.7, 60.3), among the 158 participants. The pandemic resulted in a reduction of 75.8% in the adequacy of ANC. Considering the four dimensions of adequacy, we found that having only one dimension was associated with a relative risk ratio (RRR) of 12.45 (95% CI: 6.40, 24.23), while having two or three dimensions was associated with a RRR of 5.23 (95% CI: 2.83, 9.65) when using adequate ANC as the category of reference. Conclusions: According to our results, Indigenous women's ANC adequacy was negatively affected by the COVID‐19 pandemic. In light of these findings, we emphasize the importance of developing healthcare systems that are prepared to adapt consultation schemes by implementing virtual visits and incorporating community health workers. [ABSTRACT FROM AUTHOR]

Since 2013, Permitted Development Rights (PDR) in England have allowed commercial-to-residential conversions in locations once deemed suitable only for non-residential land-use. This deregulation of planning control has been justified as a way of encouraging more home-building in areas experiencing 'housing crisis', but its overall consequences remain unclear. This paper hence compiles quantitative evidence on a city-wide scale on the price, size, build and location of these conversions in London 2013–2021. It finds that homes produced through this route are generally smaller than the London average and are over-concentrated in neighbourhoods with fewer accessible green spaces and higher-than-average levels of air pollution. Here, larger conversion schemes (of more than 10 units) appear particularly problematic, potentially subjecting residents to forms of 'slow violence' that could have long-term consequences for their physical and mental health. The paper also finds that, on average, PDR conversions are marginally more affordable than other new developments in the capital, but are also more expensive per square metre, suggesting deregulation is allowing developers to 'extract' maximum value from these schemes rather than providing affordable homes per se. The implications of this are discussed in relation to the politics of housing in London and the wider forms of planning deregulation allowing developers to accrue increased profits from housing in an era of intense financialisation. [ABSTRACT FROM AUTHOR]

Background: The utilization of smartphone-assisted evaluation is emerging in the field of histopathology. This technique improves the adequacy of samples at the bedside, avoids procedure-related complications, reduces unnecessary repeat biopsies, and saves the cost of the procedure. This study aims to compare the number of glomeruli in a renal biopsy specimen obtained by an ultrasound-guided percutaneous needle biopsy, counted at the bedside using a smartphone fitted with a 16-megapixel macro lens (Bedside method) with that observed under a light microscope after the processing of the biopsy specimen (LM method). Materials and Methods: In this prospective cohort study, 24 consecutive adult patients (48 kidney biopsy samples) who underwent kidney biopsies were enrolled. All specimens were extracted by an ultrasound-guided percutaneous renal biopsy from the lower pole of the left kidney. Patients' demographics and clinical data were prospectively collected. The number of glomeruli in all the biopsy specimens was counted using a smartphone fitted with a 16-megapixel macro lens at the bedside (Bedside method) and subsequently under a light microscope by a pathologist after processing the biopsy specimen (LM method). Seven or more glomeruli in the specimen were considered adequate in our study. Results: The mean age of patients at biopsy was 46.9 ± 16 years with slightly male predominance (54.2%). A total of 47 specimens were obtained from 24 patients. Of the 24 patients, 22 had native kidney biopsy and 2 had renal allograft biopsy. The average number of cores obtained per patient was 1.96. The length of core specimens ranged from 1.5 to 2 cm. A good agreement was found between bedside adequacy and slide adequacy, k = 0.684, P = 0.000. The positive agreement rate and negative agreement rate were 91.4% and 23.1%, respectively. Conclusion: In the modern era of technology, the smartphone is a good tool to evaluate the adequacy of biopsy specimens at the bedside. [ABSTRACT FROM AUTHOR]

Risk of bias (RoB) assessment is essential to the systematic review methodology. The new version of the Cochrane RoB tool for randomized trials (RoB 2) was published in 2019 to address limitations identified since the first version of the tool was published in 2008 and to increase the reliability of assessments. This study analyzed the frequency of usage of the RoB 2 and the adequacy of reporting the RoB 2 assessments in non-Cochrane reviews published in 2020. This meta-research study included non-Cochrane systematic reviews of interventions published in 2020. For the reviews that used the RoB 2 tool, we analyzed the reporting of the RoB 2 assessment. Among 3880 included reviews, the Cochrane RoB 1 tool was the most frequently used (N = 2228; 57.4%), followed by the Cochrane RoB 2 tool (N = 267; 6.9%). From 267 reviews that reported using the RoB 2 tool, 213 (79.8%) actually used it. In 26 (12.2%) reviews, erroneous statements were used to indicate the RoB 2 assessment. Only 20 (9.4%) reviews presented a complete RoB 2 assessment with a detailed table of answers to all signaling questions. The judgment of risk of bias by the RoB 2 tool was not justified by a comment in 158 (74.2%) reviews. Only in 33 (14.5%) of reviews the judgment in all domains was justified in the accompanying comment. In most reviews (81.7%), the RoB was inadequately assessed at the study level. In conclusion, the majority of non-Cochrane reviews published in 2020 still used the Cochrane RoB 1 tool. Many reviews used the RoB 2 tool inadequately. Further studies about the uptake and the use of the RoB 2 tool are needed. [ABSTRACT FROM AUTHOR]

Traditionally, dialysis adequacy has been assessed primarily by determining the clearance of a single small solute, urea. Nevertheless, it has become increasingly evident that numerous other factors play a crucial role in the overall well-being, outcomes and quality of life of dialysis patients. Consequently, in recent years, there has been a notable paradigm shift in guidelines and recommendations regarding dialysis adequacy. This shift represents a departure from a narrow focus only on the removal of specific toxins, embracing a more holistic, person-centered approach. This new perspective underscores the critical importance of improving the well-being of individuals undergoing dialysis while simultaneously minimizing the overall treatment burden. It is based on a double focus on both clinical outcomes and a comprehensive patient experience. To achieve this, a person-centered approach must be embraced when devising care strategies for each individual. This requires a close collaboration between the healthcare team and the patient, facilitating an in-depth understanding of the patient's unique goals, priorities and preferences while striving for the highest quality of care during treatment. The aim of this publication is to address the existing evidence on this all-encompassing approach to treatment care for patients undergoing peritoneal dialysis and provide a concise overview to promote a deeper understanding of this person-centered approach. [ABSTRACT FROM AUTHOR]

Copyright of Nefrologia is the property of Revista Nefrologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Various wind turbines have been manufactured for converting wind power into electric energy. They are fixed speed concepts with squirrel cage induction generators, limited variable speed concepts with wound rotor induction generators, variable speed concepts with double fed induction generators, direct-drive concepts with electrically excited synchronous generators and gearbox-free concepts with permanent magnet induction technologies. The composed components and the power curve of these technologies are different and to select an appropriate wind turbine for a wind site, in addition to the economic parameter, reliability criterion must be considered. To address this, a reliability model is developed in this paper that considers both component failure and the unpredictable nature of wind speed for different types of wind turbines. The optimal state number of reliability presentations is determined using XB index calculation and fuzzy c-means clustering method to create multi-state presentations for wind turbines. The proposed approach can be used to determine the most reliable wind turbine for a given wind site by assessing the adequacy of the electric network containing various types of wind turbines. The approach's effectiveness is demonstrated through adequacy assessments of the RBTS and IEEE-RTS, which contain various types of wind turbines. [ABSTRACT FROM AUTHOR]

In general, the social protection (SP) system consists of two main blocks: social insurance (SI) and social assistance (SA). The main idea of SP is to leave no one behind, support in times of social risks. However, SI and SA systems are usually developed and improved separately. Organization for Economic Cooperation and Development (OECD) and European Commission (EC) often emphasise that expenditure on the SP system in Lithuania is scarce, income poverty and inequality are critical, not improving. This raises the question of whether both elements of SP in Lithuania are based on the same criteria to achieve consolidated SP and avoid its gaps. This paper aims to identify evaluation criteria, look at the Lithuanian SP system through its main benefits, and identify whether people are protected. The analysis consists of a literature review, which helps identify evaluation criteria for the SP system, and Lithuanian analysis based on evaluation criteria for 2018-2022 policy years. Three main criteria for SP benefits evaluation are identified: coverage, adequacy, and incentives to work. To make an in-depth analysis of the SP system in Lithuania, the tax-benefit microsimulation model EUROMOD is used to analyse different households' poverty and unemployment traps and test whether the current SP system contributes to them. It was expected that this research would help to shed a light on how well Lithuanian SI and SA function simultaneously. Results show that SP system compatibility in Lithuania is above average, the weakest part is coverage. [ABSTRACT FROM AUTHOR]