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Compared with the intravenous cholangiography the infusion cholangiography is the more effective and unambiguous investigation method of the gallbladder and the bile ducts. It considerably enlarges the diagnostic possibilities in the area of the bile ducts. A serum bilirubin level of more than 2 mg/100 ml allows positive cholangiograms by means of the infusion method, but is nearly always the cause for negative findings in intravenous application. In a hypalbuminaemia lower than 3 g/100 ml, in an increase of the alkaline serum phosphatase, of the serum transaminase and a pathological retention of bromsulphalein the bile ducts cannot be demonstrated also in the infusion cholangiography. A 20% glucose solution is sufficient as solvent in the infusion cholangiography. In the negative case the cholecystography and the intravenous cholangiography may be supplemented and enlarged by application of the infusion cholangiography as a more evident method of X-ray examination.