24 results on '"Zutshi, Anup"'
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2. Identifying Safety Thresholds for Immunosuppressive Drugs: Applying Insights from Primary Antibody Deficiencies to Mitigate Adverse Events in Secondary Antibody Deficiencies Using Mathematical Modeling of Preclinical and Early Clinical Data
3. Radiolabelling and preclinical characterization of 89Zr-Df-radiolabelled bispecific anti-PD-L1/TGF-βRII fusion protein bintrafusp alfa
4. Bispecific antibodies: A guide to model informed drug discovery and development
5. Correction to: Identifying Safety Thresholds for Immunosuppressive Drugs: Applying Insights from Primary Antibody Deficiencies to Mitigate Adverse Events in Secondary Antibody Deficiencies Using Mathematical Modeling of Preclinical and Early Clinical Data
6. Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling
7. Practical guide to calculating impact of avidity in models of bispecific antibodies with two membrane-bound targets
8. Abstract 5423: Translational PK/PD/efficacy modeling and efficacious human dose prediction for a first-in-class MUC1-EGFR (M1231) bispecific antibody drug conjugate
9. Quantitative Prediction of Human Pharmacokinetics for mAbs Exhibiting Target-Mediated Disposition
10. Simulations of site-specific target-mediated pharmacokinetic models for guiding the development of bispecific antibodies
11. Application of Mechanistic Pharmacokinetic–Pharmacodynamic Modeling toward the Development of Biologics
12. A mechanistic pharmacodynamic model of IRAK-4 drug inhibition in the Toll-like receptor pathway
13. Erratum to: Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling
14. Quantitative Systems Pharmacology Approaches for Immuno‐Oncology: Adding Virtual Patients to the Development Paradigm
15. Radiolabelling and preclinical characterization of 89Zr-Df-radiolabelled bispecific anti-PD-L1/TGF-βRII fusion protein bintrafusp alfa.
16. Guiding principles for mechanistic modeling of bispecific antibodies
17. Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling
18. Quantitative Prediction of Human Pharmacokinetics for mAbs Exhibiting Target-Mediated Disposition
19. Pharmacokinetics for Medicinal Chemists
20. Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS)
21. Saturation of Multidrug-Resistant Protein 2 (Mrp2/Abcc2)-Mediated Hepatobiliary Secretion: Nonlinear Pharmacokinetics of a Heterocyclic Compound in Rats after Intravenous Bolus Administration
22. TOXICOKINETICS OF 2-METHYLIMIDAZOLE IN MALE AND FEMALE F344 RATS
23. Evaluation of the systemic toxicity and pharmacokinetics of the immunoconjugate anti-B4-blocked ricin in non-human primates. Delivered by multiple bolus injections and by continuous infusion
24. Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm.
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