24 results on '"Zsolt Juhasz"'
Search Results
2. Chondromesenchymal Hamartoma in Ectopic Thyroid Tissue in a Neonate
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Noémi Benedek, Anna Kover, Endre Kálmán, Béla Kajtár, Tamás Kövesi, Agnes Szepesi, Zsolt Juhasz, Peter Vajda, and Marianna Imre
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Pathology ,medicine.medical_specialty ,Ectopic thyroid tissue ,ectopic ,lcsh:Surgery ,Case Report ,Left sided ,thyroid ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,Medicine ,Hamartoma ,chondromesenchymal ,medicine.diagnostic_test ,business.industry ,Thyroid ,lcsh:RJ1-570 ,lcsh:Pediatrics ,Magnetic resonance imaging ,Solid mass ,Histology ,lcsh:RD1-811 ,medicine.disease ,medicine.anatomical_structure ,hamartoma ,030211 gastroenterology & hepatology ,business - Abstract
A full-term male neonate presented with a left sided cervical lump at the level of the thyroid gland. Magnetic resonance imaging (MRI) showed a benign heterogeneous solid mass with lobulated margins. The tumor underwent complete excision. Histology revealed the diagnosis of chondromesenchymal hamartoma in ectopic thyroid tissue.
- Published
- 2019
3. 4 - Treatment of partial thickness facial burn injuries in children with zinc-hyaluronic gel
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Zsolt Juhasz and Józsa Gergő
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- 2019
4. 5 - Treatment of partial thickness hand burn injuries in children with combination of silver foam dressing and zinc-hyaluronic gel
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Zsolt Juhasz and Józsa Gergő
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- 2019
5. 3 - Comparsion of traditional and modern dressing methods on children with deep burn injury after autologous transplant
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Zsolt Juhasz and Józsa Gergő
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- 2019
6. Distance of the fracture from the radiocarpal surface in childhood: does it determine surgical technique? A retrospective clinical study
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Zsolt Juhasz, Gertrud Devecseri, Peter Vajda, Marcell Varga, Gergo Jozsa, and Tamás Juhász
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Orthodontics ,Osteosynthesis ,business.industry ,Radiography ,Ulna ,General Medicine ,Radius ,medicine.disease ,law.invention ,Intramedullary rod ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Forearm ,law ,030220 oncology & carcinogenesis ,Fracture fixation ,Medicine ,Left axis deviation ,030212 general & internal medicine ,business - Abstract
Unstable distal metaphyseal and dia-metaphyseal fractures of the radius may have treated with a variety of operative techniques, Kirschner wires (K-wires), dorsally inserted titanium elastic stable intramedullary nailing (DESIN), and short titanium elastic stable intramedullary nailing (SESIN) in children.The aim of this study was to evaluate the differences in clinical and radiographic outcomes between these methods.Between January 2009 and December 2017 196 children were treated for forearm fractures in the distal third of the distal radius. Gender of the patients, different types of surgical techniques, number of postoperative X-rays, date of metal removal and degree of axis deviation after the metal removal were studied. Distance of the fracture line from the radiocarpal surface, the width of the distal epiphysis of the radius, and the cumulative width of the distal epiphysis of the ulna and radius were analyzed.Out of the 196 children, stabilization of the fracture was achieved by K-wire in 139, by DESIN in 44, and by SESIN in 13 patients. The average time of metal removal was significantly shorter (3.8 months), following stabilization with K-wire. In children treated with K-wire, axial deviation of
- Published
- 2020
7. Az olecranon és a radius fej egyidejű nagy elmozdulással járó törésének kezelése gyermekkorban
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Tamás Kassai, Zsolt Juhasz, and Gergő Józsa
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General Medicine - Published
- 2015
8. Composite Urinary Reservoir in Dogs: Histological Findings
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Attila M. Vastyan, Peter Vajda, Zsolt Juhasz, László Kereskai, Csaba Jakab, Zoltan Farkas Kispal, and Andrew Pintér
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Pathology ,medicine.medical_specialty ,Biopsy ,Urology ,Urinary system ,H&E stain ,Cystectomy ,Beagle ,Dogs ,Proliferating Cell Nuclear Antigen ,Carcinoma ,Animals ,Medicine ,Urinary bladder ,business.industry ,Urinary Reservoirs, Continent ,Histology ,medicine.disease ,Immunohistochemistry ,medicine.anatomical_structure ,Urinary Bladder Neoplasms ,Bladder augmentation ,Dysplasia ,Models, Animal ,Female ,business - Abstract
This animal study was designed to investigate whether the composite urinary reservoir might lessen the premalignant histological alterations observed after bladder augmentation performed with a gastric segment or large bowel.Composite urinary reservoirs were created using gastric and colonic segments simultaneously in 8, 3-month-old female beagle dogs by augmenting half the native bladder. Two dogs with gastrocystoplasty and 2 with colocystoplasty served as controls. Biopsies were taken from the native bladder, and the gastric and colonic segments at augmentation, and endoscopically 4 and 8 months postoperatively. The dogs were sacrificed and open biopsied 12 months postoperatively. Tissue specimens were examined with routine hematoxylin and eosin, reaction and immunohistological staining for PCNA.At the creation of composite reservoir and gastrocoloplasty or colocystoplasty all specimens showed normal histology. At 12 months postoperatively dysplasia was found in 1 gastric segment, 2 native bladders and 3 colonic segments in the composite reservoir group. There was a single carcinoma in situ in 1 gastric segment in the composite reservoir group. In the control groups 1 colonic segment and 1 native bladder dysplasia were detected at the end of 12-month followup. There was an in situ carcinoma in 1 gastric segment in the composite reservoir.A composite reservoir did not decrease premalignant changes in dogs during 12 months of followup. Laboratory investigations, molecular studies and longer followup are needed to approach the question of early malignant alterations after augmentation cystoplasty in animals and patients.
- Published
- 2012
9. Diaphragmatic hernia or hiatus hernia: a diagnostic problem in 5-month-old infant
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András Pintér, Zsolt Juhasz, Gergő Józsa, Peter Vajda, and Gabriella Mohay
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medicine.medical_specialty ,Vomiting ,Contrast Media ,Diaphragmatic breathing ,Diagnosis, Differential ,Hiatal hernia ,chemistry.chemical_compound ,Recurrence ,medicine ,Humans ,Hernia ,Diaphragmatic hernia ,Respiratory Tract Infections ,Hernia, Diaphragmatic ,business.industry ,Infant ,Congenital diaphragmatic hernia ,General Medicine ,medicine.disease ,digestive system diseases ,Failure to Thrive ,Surgery ,Diaphragm (structural system) ,Barium sulfate ,Hernia, Hiatal ,chemistry ,Female ,Radiography, Thoracic ,Barium Sulfate ,medicine.symptom ,Hernias, Diaphragmatic, Congenital ,business - Abstract
Authors present a case of a 5-month-old infant, in whom following an uneventful perinatal adaptation, symptoms of recurrent respiratory infections, vomiting and growth failure developed. Based on chest X-ray, right-sided diaphragmatic hernia was suspected. However, barium swallow examination delineated the stomach above the right diaphragm. The case report draws attention to the differential diagnostic difficulties between congenital diaphragmatic and hiatal hernia. Orv. Hetil., 2011, 152, 1500–1503.
- Published
- 2011
10. Complications after bladder augmentation or substitution in children: a prospective study of 86 patients
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András Pintér, Peter Vajda, András Farkas, Zsolt Juhasz, Attila M. Vastyan, Zoltan Farkas Kispal, Daniel L. Balogh, Orsolya Erdei, and Dániel Kehl
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medicine.medical_specialty ,Urinary bladder ,business.industry ,Urology ,medicine.medical_treatment ,Urinary system ,urologic and male genital diseases ,medicine.disease ,Urinary catheterization ,Surgery ,Urethra ,medicine.anatomical_structure ,Bladder augmentation ,Stoma (medicine) ,medicine ,Bladder stones ,business ,Complication - Abstract
OBJECTIVE • To evaluate complications after urinary bladder augmentation or substitution in a prospective study in children. PATIENTS AND METHODS • Data of 86 patients who underwent urinary bladder augmentation (80 patients) or substitution (6 patients) between 1988 and 2008 at the authors' institute were analysed. • Ileocystoplasty occurred in 32, colocystoplasty in 30 and gastrocystoplasty in 18. Urinary bladder substitution using the large bowel was performed in six patients. • All patients empty their bladder by intermittent clean catheterization (ICC), 30 patients via their native urethra and 56 patients through continent abdominal stoma. Mean follow-up was 8.6 years. • Rate of complications and frequency of surgical interventions were statistically analysed (two samples t-test for proportions) according to the type of gastrointestinal part used. RESULTS • In all, 30 patients had no complications. In 56 patients, there were a total of 105 complications (39 bladder stones, 16 stoma complications, 11 bowel obstructions, 5 reservoir perforations, 7 VUR recurrences, 1 ureteral obstruction, 4 vesico-urethral fistulae, 4 orchido-epididymitis, 4 haematuria-dysuria syndrome, 3 decreased bladder capacity/compliance, 3 pre-malignant histological changes, 1 small bowel bacterial overgrowth and 7 miscellaneous). • In 25 patients, more than one complication occurred and required 91 subsequent surgical interventions. Patients with colocystoplasty had significantly more complications (P < 0.05), especially more stone formation rate (P < 0.001) and required more post- operative interventions (P < 0.05) than patients with gastrocystoplasty and ileocystoplasty. CONCLUSIONS • Urinary bladder augmentation or substitution is associated with a large number of complications, particularly after colocystoplasty. • Careful patient selection, adequate preoperative information and life-long follow-up are essential for reduction, early detection and management of surgical and metabolic complications in patients with bladder augmentation or substitution.
- Published
- 2010
11. Treatment of partial thickness hand burn injuries in children with combination of silver foam dressing and zinc-hyaluronic gel
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Zsolt Juhasz, Peter Vajda, Gergo Jozsa, Alexandra Csenkey, and András Garami
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Male ,medicine.medical_specialty ,Silver ,MEDLINE ,macromolecular substances ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,children ,silver foam dressing ,medicine ,Humans ,second burn hand injury ,Prospective Studies ,Clinical Case Report ,Child ,Prospective cohort study ,Wound Healing ,treatment ,integumentary system ,business.industry ,030208 emergency & critical care medicine ,General Medicine ,Hand ,Bandages ,Surgery ,Clinical trial ,Zinc ,Traumatic injury ,Zn-hyaluronic gel ,Child, Preschool ,Female ,Burns ,business ,Gels ,Research Article ,Partial thickness - Abstract
Rationale: Burns is a common type of traumatic injury in childhood. Nowadays, several wound dressings are available to treat the second-degree hand burns conservatively. Patient concerns, diagnoses: At the authors’ institute, 37 children were treated conservatively with a special dressing at first intervention containing Aquacel Ag foam and Zn-hyaluronic gel to determine their effectiveness on partial thickness hand burns. Interventions: The dressing was checked on the second day, and removed on the sixth or seventh day (unless it had spontaneously separated). Outcomes: None of the 37 children treated with this dressing were diagnosed with wound infection. The authors observed the epithelialization of the burned areas on the 6-7th day after primary conservative treatment. The dressing efficiently promotes epithelialization in all cases. Further advantage of Zn-hyaluronic gel is to enhance cell regeneration and inhibits dressing fixation into the wound. Lessons: Based on the authors’ experience, with this special combination of wound dressing, a gentle, child-friendly, cost-effective treatment and excellent wound healing observed with favourable cosmetic results.
- Published
- 2018
12. Does the type of bladder augmentation influence the resolution of pre-existing vesicoureteral reflux? Urodynamic studies
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Zsolt Oberritter, Reka Somogyi, Peter Vajda, Andrew Pintér, Khaled Fathi, and Zsolt Juhasz
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Male ,medicine.medical_specialty ,Meningomyelocele ,Adolescent ,Colon ,Urology ,medicine.medical_treatment ,Urinary Bladder ,Urodynamic studies ,urologic and male genital diseases ,Urologic Surgical Procedure ,Vesicoureteral reflux ,Urinary catheterization ,Pressure ,Humans ,Medicine ,Child ,Augmentation cystoplasty ,Retrospective Studies ,Vesico-Ureteral Reflux ,business.industry ,Bladder Exstrophy ,Stomach ,Urinary Bladder Diseases ,Reflux ,Retrospective cohort study ,medicine.disease ,female genital diseases and pregnancy complications ,Surgery ,Intestines ,Urodynamics ,Treatment Outcome ,Bladder augmentation ,Urologic Surgical Procedures ,Female ,Neurology (clinical) ,Urinary Catheterization ,business ,Follow-Up Studies - Abstract
Aims The type of bladder augmentation on pre-existing vesicoureteral reflux (VUR) was assessed. The effects of urodynamic changes on the resolution of VUR following augmentation cystoplasty performed with various gastrointestinal segments were examined. It was queried whether elimination of high-pressure bladder is sufficient to resolve pre-existing reflux. Methods A retrospective record review of patients who underwent bladder augmentation between 1987 and 2004. Patients were divided into two groups. Group I included patients who had a simultaneous augmentation and ureteral reimplantation. Group II included patients with reflux in whom only a bladder augmentation was performed. Pre-and post-augmentation urodynamic results were compared in both groups. The outcome of VUR and the role of various gastrointestinal (GI) segments on the resolution of VUR were studied. Results Sixty-three patients underwent bladder augmentation during the study period. Twenty-six of them had VUR before augmentation. There were 10 patients in Group I and 16 patients in Group II. In Group I, VUR ceased in all patients, while in group II, VUR resolved in 14 patients and persisted in two patients. Small and large bowel segments used for augmentation had no effect on the resolution of VUR but the results of gastrocystoplasties were less favorable. Urodynamically there was no significant difference between the various augmentation cystoplasties. Conclusions Bladder augmentation alone without simultaneous antireflux repair is usually sufficient for the resolution of pre-existing reflux. The various GI segments used for augmentation have no effect on urodynamic results and the resolution of VUR. Neurourol. Urodynam. 27:412–416, 2008. © 2007 Wiley-Liss, Inc.
- Published
- 2008
13. A therapeutic method for failed bladder augmentation in children: re-augmentation
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Peter Vajda, Cenk Büyükünal, Yunus Söylet, Zsolt Juhasz, Andrew Pintér, and Nur Danismed
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Adult ,Reoperation ,Nephrology ,medicine.medical_specialty ,Adolescent ,Turkey ,medicine.drug_class ,Urology ,Early detection ,Urinary incontinence ,Bladder capacity ,Urinary Diversion ,Internal medicine ,medicine ,Anticholinergic ,Humans ,Treatment Failure ,Child ,Hungary ,Urinary bladder ,business.industry ,Stomach ,Urinary Reservoirs, Continent ,Urinary Bladder Diseases ,Surgery ,Intestines ,Urinary Incontinence ,medicine.anatomical_structure ,Bladder augmentation ,Child, Preschool ,medicine.symptom ,business - Abstract
OBJECTIVE To investigate the causes leading to the deterioration of previously successful bladder augmentation and to evaluate the efficacy of re-augmentation. PATIENTS AND METHODS Between 1988 and 2004, 136 bladder augmentations were performed in two paediatric urological units in Hungary and Turkey. Re-augmentation was necessary in two patients after colocystoplasty and in three after gastrocystoplasty. A secondary augmentation was not required in any patients after ileocystoplasty. The clinical data of these five patients were evaluated. RESULTS On the basis of the clinical signs and urodynamic studies, re-augmentation was performed 2–7 years after the initial augmentation cystoplasties. Anticholinergic therapy given before re-augmentation did not improve bladder capacity, intravesical pressure and/or bladder compliance. An ileal or sigmoid segment was used for the secondary augmentation. After re-augmentation, all five patients became continent, and showed marked improvement in their urodynamic parameters at a mean (range) follow-up of 6.8 (2–10) years. CONCLUSION A decreased bladder capacity and/or compliance and increased bladder pressure after successful augmentation cystoplasty might be the result of: (i) impairment of the blood supply to the large bowel or gastric segment used for augmentation; or (ii) bowel mass contractions. Ileocystoplasty seems to be the ‘first-line’ of choice for primary augmentation. Re-augmentation with a bowel segment is a suitable treatment if conservative treatment fails. Regular urodynamic investigations are needed for early detection of malfunction of the augmented bladder, and advising therapy.
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- 2006
14. Histologic findings after gastrocystoplasty in rabbits
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Tamás Magyarlaki, Peter Vajda, Andrew Pintér, Khaled Fathi, Zsolt Juhasz, Zsolt Oberritter, and Attila M. Vastyan
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Male ,Pathology ,medicine.medical_specialty ,Urinary Bladder ,Inflammation ,Urine ,Malignancy ,Postoperative Complications ,Atrophy ,Risk Factors ,Metaplasia ,medicine ,Gastric mucosa ,Animals ,Hyperplasia ,business.industry ,Stomach ,General Medicine ,medicine.disease ,digestive system diseases ,Cell Transformation, Neoplastic ,Treatment Outcome ,Urinary Incontinence ,medicine.anatomical_structure ,Urinary Bladder Neoplasms ,Bladder augmentation ,Gastric Mucosa ,Dysplasia ,Pediatrics, Perinatology and Child Health ,Urologic Surgical Procedures ,Surgery ,Rabbits ,medicine.symptom ,business - Abstract
The aim of this study was to investigate the long-term histologic changes after bladder augmentation with gastric segment in an animal subject.Gastrocystoplasty was performed in 13 young, 3-month-old male rabbits. Open biopsies were taken from the native bladder and the gastric segment preoperatively and at 3, 6, and 12 months postoperatively. Sections were examined with HE and periodic acid-Schiff (PAS) staining. Indirect immune peroxidase method was additionally applied to detect the carcinoembrionic antigen, the proliferative activity, and the gene for the tumor protein p53 in the epithelium.On the native bladder, at the 3-month follow-up, polyps, mucosal edema, submucosal fibrosis, and squamous cell metaplasia were detected, which did not change during the follow-up. On the gastric segment, at the 3-month follow-up, parietal cell hyperplasia and inflammatory mucosal overgrowth were detected; at the 6-month follow-up, inflammation or atrophy of the gastric mucosa and colonic-type metaplasia was found. These alterations remained unchanged during later course of follow-up. Neither dysplasia nor malignancy was observed during the 12-month follow-up.The present study supports the clinical observations of low cancer risk after gastrocystoplasty and may indicate different effect of gastric secretion on uroepithelium and that of urine on gastric mucosa.
- Published
- 2005
15. Cutaneous Vesicostomy Revisited - the Second 15 Years
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Andrew Pintér, Zsolt Juhasz, Peter Vajda, Attila M. Vastyan, Reka Somogyi, and András Farkas
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Male ,Reoperation ,Gynecology ,medicine.medical_specialty ,business.industry ,Urinary Bladder ,Infant, Newborn ,Infant ,Urinary Diversion ,Infant newborn ,Urethra ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Humans ,Medicine ,Female ,Surgery ,Urinary Bladder, Neurogenic ,Cutaneous vesicostomy ,Child ,business ,Derivacion urinaria - Abstract
Le but de cette etude est de revoir la fonction de la vesicostomie (CV) au cours des 15 dernieres annees incluant les indications, les resultats et les complications. Materiels et Methodes: Les dossiers de 31 patients traites par CV entre 1987 et 2002 ont ete revus. Il y avait 20 garcons et 11 filles. Les deux principales etiologies etaient la vessie neurologique (19 patients) et la valve de l'uretre posterieure (PUV) (7 patients). Tous les patients ont ete traites par l'operation de Blocksome a l'age moyen de 23 mois (moyenne 14 jours - 9 ans). Une cystomanometrie pre et post operatoire etait realisee chez 18 patients (58%) et la fonction vesicale a ete etudiee. Resultats: Chez 23 patients (74%), la CV realisait une diversion satisfaisante avec une amelioration du tractus urinaire et/ou la stabilisation de la fonction renale. Chez 5 patients (16%) avec PUV l'amelioration a ete temporaire. Chez 3 patients (10%) la CV n'a entraine aucune amelioration. Vingt-quatre patients ont eu la fermeture de leur CV apres une periode de 23 mois (moyenne 1 mois - 7 ans) de diversion. Chez 2 patients avec myelomeningocele (MMC) et severe retard mental, CV n'a pas ete ferme et considere comme un traitement permanent. Les etudes urodynamiques chez 5 patients avec PUV montraient une compliance alteree et une pression intravesicale elevee apres resection de valve de l'uretre et fermeture de CV. Dans le groupe des vessies neurologiques, la fonction vesicale etait amelioree apres fermeture de CV et la mise en route d'une medication anti-cholinergique et d'un auto catheterisme (CIC). Notre ratio d'amelioration dans les vessies neurologiques etait de 22%. Les complications du CV etaient les suivantes: stenose chez 7 patients (22%), prolapsus chez 2 (6%), et infection chez 2 patients (6%). Le taux de revisions etait de 16%. Conclusion: Chez les jeunes patients, CV a des resultats moins favorables dans les PUV que dans les cas de vessies neurologiques avec dilatation du tractus superieur et infection urinaire severe (UTI), ou CV entraine une decompression et previent la deterioration de la fonction renale. La vesicostomie a resiste a l'epreuve du temps dans notre pratique urologique et demeure une arme valable pour l'urologue pediatre chez les patients selectionnes.
- Published
- 2005
16. Complications after bladder augmentation or substitution in children: a prospective study of 86 patients
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Zoltan, Kispal, Daniel, Balogh, Orsolya, Erdei, Daniel, Kehl, Zsolt, Juhasz, Attila M, Vastyan, Andras, Farkas, Andras B, Pinter, and Peter, Vajda
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Adult ,Adolescent ,Patient Selection ,Urinary Bladder ,Urinary Reservoirs, Continent ,Urinary Diversion ,Young Adult ,Postoperative Complications ,Urinary Incontinence ,Child, Preschool ,Humans ,Child ,Epidemiologic Methods ,Urinary Catheterization - Abstract
• To evaluate complications after urinary bladder augmentation or substitution in a prospective study in children.• Data of 86 patients who underwent urinary bladder augmentation (80 patients) or substitution (6 patients) between 1988 and 2008 at the authors' institute were analysed. • Ileocystoplasty occurred in 32, colocystoplasty in 30 and gastrocystoplasty in 18. Urinary bladder substitution using the large bowel was performed in six patients. • All patients empty their bladder by intermittent clean catheterization (ICC), 30 patients via their native urethra and 56 patients through continent abdominal stoma. Mean follow-up was 8.6 years. • Rate of complications and frequency of surgical interventions were statistically analysed (two samples t-test for proportions) according to the type of gastrointestinal part used.• In all, 30 patients had no complications. In 56 patients, there were a total of 105 complications (39 bladder stones, 16 stoma complications, 11 bowel obstructions, 5 reservoir perforations, 7 VUR recurrences, 1 ureteral obstruction, 4 vesico-urethral fistulae, 4 orchido-epididymitis, 4 haematuria-dysuria syndrome, 3 decreased bladder capacity/compliance, 3 pre-malignant histological changes, 1 small bowel bacterial overgrowth and 7 miscellaneous). • In 25 patients, more than one complication occurred and required 91 subsequent surgical interventions. Patients with colocystoplasty had significantly more complications (P0.05), especially more stone formation rate (P0.001) and required more post- operative interventions (P0.05) than patients with gastrocystoplasty and ileocystoplasty.• Urinary bladder augmentation or substitution is associated with a large number of complications, particularly after colocystoplasty. • Careful patient selection, adequate preoperative information and life-long follow-up are essential for reduction, early detection and management of surgical and metabolic complications in patients with bladder augmentation or substitution.
- Published
- 2010
17. Combination of vesicoureteric reflux and vesicoureteric junction obstruction
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Peter Vajda, Andrew Pintér, Zsolt Oberritter, Zsolt Juhasz, and Reka Somogyi
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Nephrology ,Male ,medicine.medical_specialty ,Urology ,Urinary Bladder ,Comorbidity ,urologic and male genital diseases ,Vesicoureteral reflux ,Ureter ,Internal medicine ,Vesicoureteric reflux ,Medicine ,Humans ,Child ,Radionuclide Imaging ,Retrospective Studies ,Ultrasonography ,Female to male ,Vesico-Ureteral Reflux ,medicine.diagnostic_test ,business.industry ,Infant ,medicine.disease ,Magnetic Resonance Imaging ,female genital diseases and pregnancy complications ,Endoscopy ,Surgery ,medicine.anatomical_structure ,Child, Preschool ,Female ,business ,Surgical interventions ,Vesicoureteric junction ,Ureteral Obstruction - Abstract
This study analysed the association of vesicoureteric reflux (VUR) and vesicoureteric junction obstruction (VUJO) requiring surgical interventions in infants and children.Over 30 years (1975-2004) 423 infants and children were operated on because of VUR, 163 owing to VUJO and 25 patients (33 ureters) with a combination of VUR and obstruction of the vesicoureteric junction on the same side. For both pathological entities ureteral reimplantation was performed along with excision of the narrowed and refluxing distal ureteric segment. The age of patients at surgery ranged from 3 months to 11 years (average 2.6 years). The female to male ratio was 1.4:1.Out of the 25 patients (33 ureters), both entities were diagnosed before surgery in 10 of them (15 ureters). In 15 cases (18 ureters), only the VUR was preoperatively diagnosed; however, the VUJO was only suspected and confirmed during the operation. In one refluxing ureter, the obstruction was not diagnosed during subureteric endoscopic injection of the orifice. In five of the 33 ureters, redo reimplantation was necessary because of obstruction (four ureters) or reflux (one ureter).A combination of VUR and VUJO should be taken into consideration in a patient with proven reflux, where the ureter is dilated and tortuous and following urination the hydronephrosis and hydroureter persist or slowly decrease. In such cases long-term prophylaxis and endoscopic treatment are contraindicated but open surgery (reimplantation) is recommended.
- Published
- 2009
18. Altered expression of c-kit-positive cells in the ureterovesical junction after surgically created vesicoureteral reflux
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Prem Puri, Zsolt Oberritter, Udo Rolle, Zsolt Juhasz, and Tamás Cserni
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Pathology ,medicine.medical_specialty ,Swine ,Urinary system ,Population ,Urinary Bladder ,Urology ,urologic and male genital diseases ,Vesicoureteral reflux ,Ureter ,medicine ,Animals ,education ,Upper urinary tract ,Peristalsis ,Vesico-Ureteral Reflux ,education.field_of_study ,Immunity, Cellular ,business.industry ,General Medicine ,medicine.disease ,Immunohistochemistry ,Disease Models, Animal ,Proto-Oncogene Proteins c-kit ,medicine.anatomical_structure ,Pediatrics, Perinatology and Child Health ,Ureterovesical Junction ,Swine, Miniature ,Surgery ,Urothelium ,business ,Renal pelvis - Abstract
Peristaltic contractions propel urine unidirectionally from the renal pelvis trough the ureter and into the bladder. A morphologically and functionally competent ureterovesical junction prevents vesicoureteral reflux (VUR). According to current knowledge, pyeloureteral peristalsis is driven by atypical muscle cells within the upper urinary tract. Another likely relevant cell population, which is c-kit-positive, has been shown to be present within the whole urinary tract. Morphological changes of c-kit-positive cells have been described in VUR and pyeloureteral junction (PUJ) obstruction. Nevertheless, the functional importance of c-kit-positive interstitial cells has not yet been elucidated fully. Therefore, we investigated the influence of experimentally created VUR on the expression of c-kit-positive cells.We created left-sided unilateral VUR in eight Vietnamese pigs using an open surgical technique. The VUR was shown to be grade II-III by voiding cystourethrogram (VCUG), 1 and 6 months after the procedure. The animals were killed after 6 months. The vesicoureteral junction and the distal ureters were excised and fixed in 4% PFA. Paraffin sections were stained using c-kit immunohistochemistry. A quantitative evaluation was performed by two independent investigators. The unaffected, contralateral, nonrefluxing ureters served as controls.We identified two types of c-kit-immunoreactive cells within the ureterovesical junction and distal ureter. The first group was comprised of round-shaped cells with substantial intracellular granulas, which resembled mast cells. Mast cells were found in the subepithelial region as well as between the muscle bundles. The number of mast cells was slightly increased in the VUR group. The second group consisted of spindle-shaped, bipolar ICC-like cells, which were seen mainly in the submucosal and muscular layers. The number of spindle-shaped c-kit-immunoreactive cells was markedly decreased in the refluxing ureter compared to the controls.Surgically created VUR leads to altered expression of c-kit-positive cells. The altered distribution of c-kit-positive ICC-like cells might further contribute to the impairment of coordinated pyeloureteral peristalsis.
- Published
- 2009
19. Pancreatic carcinoid in childhood
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Zsolt Juhasz, Peter Vajda, Dezso Kelemen, Andrew Pintér, and Örs Péter Horváth
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Pancreatic Neoplasms ,Radiography ,medicine.medical_specialty ,business.industry ,General surgery ,Pediatrics, Perinatology and Child Health ,medicine ,Humans ,Surgery ,Female ,Carcinoid Tumor ,business ,Child - Published
- 2009
20. Laparoscopic repair of circumcaval ureter: one-year follow-up of three patients and literature review
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Tamas Beothe, Csaba Pusztai, E. Holman, Bányai Dániel, Arpad Szanto, Fariborz Bagheri, László Farkas, and Zsolt Juhasz
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Nephrology ,Adult ,Male ,medicine.medical_specialty ,Time Factors ,Adolescent ,Urology ,medicine.medical_treatment ,Vena Cava, Inferior ,Anastomosis ,Prosthesis Design ,Circumcaval Ureter ,Ureter ,Internal medicine ,medicine ,Humans ,Laparoscopy ,medicine.diagnostic_test ,business.industry ,Stent ,Endoscopy ,Surgery ,medicine.anatomical_structure ,Ureteral Stricture ,Female ,Stents ,business ,Vascular Surgical Procedures ,Follow-Up Studies - Abstract
Objectives To describe our experience and 1-year follow-up of 3 patients with circumcaval ureter (CU) treated laparoscopically, with the introduction of a new stenting method and review of the published data. Because of its rarity, more reports are needed to advocate more comprehensive knowledge about the preferred surgical technique for the treatment of CU. Methods Since November 2005, 3 patients with symptomatic CU have undergone laparoscopic repair of their anomaly at our institutes. In all 3 cases, the ureter was transected and positioned anteriorly with an end-to-end anastomosis. In 2 cases, the retrocavally located ureteral segment was resected. Results The mean operative time in our series was 210 minutes, without any intraoperative or early postoperative complications. In 1 patient, a slight ureteral stricture was detected that resolved with reinsertion of a double-J stent. Histopathologic examination of the resected ureteral segments revealed sclerosis and muscular hypertrophy. All patients remained symptom free during the 1 year of follow-up. Conclusions With all the advantages of a minimally invasive procedure and preserving therapeutic efficacy, the laparoscopic approach should be considered a standard choice for surgical treatment of CU in symptomatic patients. Care should be taken to diagnose and excise the pathologically narrowed ureteral segment.
- Published
- 2008
21. Mid-Term Follow-Up Study of Children Undergoing Autologous Skin Transplantation for Burns
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Angyalka Válik, Katalin Harangozó, András Garami, Zsolt Juhász, Gergő Józsa, and Aba Lőrincz
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paediatric ,burn ,skin ,graft ,scar ,POSAS ,Science - Abstract
Deep partial and full-thickness burns require surgical treatment with autologous skin grafts after necrectomy, which is the generally accepted way to achieve permanent wound coverage. This study sought to examine the grafted and donor areas of children who underwent autologous skin transplantation, using two assessment scales to determine the severity of the scarring and the cosmetic outcome during long-term follow-up. At the Surgical Unit of the Department of Paediatrics of the University of Pécs, between 1 January 2015 and 31 December 2019, children who had been admitted consecutively and received autologous skin transplantation were analyzed. Twenty patients met the inclusion criteria in this retrospective cohort study. The authors assessed the results using the Patient and Observer Scar Assessment Scale (POSAS) and the Vancouver Scar Scale (VSS). There was a significant difference in how parents and examiners perceived the children’s scars. In the evaluation of the observer scale, the most critical variables for the area of skin grafted were relief and thickness. Besides color, relief was the worst clinical characteristic on the patient scale. However, when medical professionals evaluated the donor site, significantly better results were obtained compared to the transplanted area (average observer scale score: 1.4 and 2.35, p = 0.001; VSS: 0.85 vs. 2.60, p < 0.001), yet it was similar to the graft site in the parents’ opinion (Patient Scale: 2.95 and 4.45, p = 0.181).
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- 2023
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22. Role of the Teflon deposit in the recurrence of vesicoureteral reflux
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Andrew Pintér, Zsolt Oberritter, Reka Somogyi, and Zsolt Juhasz
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Male ,medicine.medical_specialty ,Time Factors ,Urinary system ,Urology ,chemistry.chemical_element ,Biocompatible Materials ,Bacteriuria ,urologic and male genital diseases ,Scintigraphy ,Technetium ,Vesicoureteral reflux ,Injections ,Recurrence ,medicine ,Humans ,Child ,Radionuclide Imaging ,Polytetrafluoroethylene ,Retrospective Studies ,Reflux nephropathy ,Vesico-Ureteral Reflux ,medicine.diagnostic_test ,business.industry ,Reflux ,Urography ,medicine.disease ,female genital diseases and pregnancy complications ,Surgery ,Treatment Outcome ,chemistry ,Nephrology ,Dimercaptosuccinic acid ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Female ,Ureter ,business ,medicine.drug ,Follow-Up Studies - Abstract
A relationship between the Teflon deposit, visible with ultrasound, and long-term success of subureteric Teflon injection (STING) treatment was investigated. The study included only those patients with primary vesicoureteral reflux (VUR), in whom the reflux had disappeared and the Teflon deposits were visible 6 weeks following STING treatment. Cessation of VUR was proven by voiding cysto-urethrography (VCUG) in 99 patients (143 ureters). Average follow-up time was 9 (4–12) years. Patients were divided into two groups: group I, deposits visible with ultrasound [deposit (+)], and group II, no visible deposits at the end of the follow-up period [deposit (−)]. Reflux recurrence, the occurrence of urinary tract infection (UTI), and pyelonephritis were investigated, and technetium scintigraphy scans were examined. The deposit (+) group included 43 patients (65 ureters), and the deposit (−) group contained 56 patients (78 ureters). In the deposit (+) group there were no recurrences of VUR; however, 17 recurrences were found in the deposit (−) group (P
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- 2007
23. The introduction of health behavior profiles in the Hungarian Defense Forces: a cluster analysis of lifestyle factors according to the health screening tests performed in 2011–2015
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Attila Novák, Beatrix Hornyák, Zsófia Rázsó, Szabolcs Szalánczi, Andrea Sótér, Zsolt Juhász, and Csaba Nyakas
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health promotion ,cluster analysis ,health behavior ,Hungarian Defense Forces ,health profile ,military health ,Medicine - Abstract
Objectives The main aim of this study was to examine the health behavior patterns of soldiers in the Hungarian Defense Forces and to introduce health behavior profiles according to the cluster analysis of lifestyle factors. Material and Methods The soldiers (N = 5475) who underwent health tests in 2011–2015 participated in this cross-sectional study. The factors included in the analysis are the following: age, sex, diseases diagnosed, the body mass index, eating habits, the smoking status, daily physical activity, sporting habits, the presence of psychosomatic symptoms, mental toughness and sleep apnea. The response options for each factor were scored on a linear scale; the minimum number of points available was –47.5 pts and the maximum number was 48.5 pts according to the 24 factors. Finally, the authors created health profiles typical of the pattern with the cluster analysis of the data. Results As a result of the cluster analysis, 16 distinct profiles were found, 10 of which differed significantly (p < 0.05) from each other. The lowest point value achieved was 3.1 pts and the highest was 26.2 pts. The lowest number of points was achieved by the cluster, 1.8% of the sample, with the highest average age (43.5±7.2 years) in which women showed the highest participation (46%). The 2 clusters with the highest numbers of points, 2.9% and 5.5% of the sample, were the 2 groups with the lowest average age (33.7±7.1 years and 34.3±7.9 years). Conclusions The significance of the health profiles obtained during this examination with the Hungarian Defense Forces is that the health promotion intervention opportunities may be determined by clusters, the health behavior factor with which the authors can reach higher health benefits can be chosen and the effectiveness of the interventions carried out can be traced easily. Int J Occup Med Environ Health. 2019;32(1):99–114
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- 2019
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24. Management of Pediatric Facial Burns with Zinc-Hyaluronan Gel
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Aba Lőrincz, Anna Gabriella Lamberti, Zsolt Juhász, András Garami, and Gergő Józsa
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pediatric ,facial burn ,partial-thickness burn ,zinc-hyaluronate ,Pediatrics ,RJ1-570 - Abstract
Zinc-hyaluronan-containing burn dressings have been associated with enhanced reepithelialization and low infection rates, although their effectiveness has not yet been investigated in pediatric facial thermal injuries. This single-arm, retrospective cohort study assessed the characteristics of 23 children (≤17-year-old) with facial superficial partial-thickness burns and the wound closure capabilities of the applied zinc-hyaluronan gel. Patients were admitted consecutively to the Pediatric Surgery Division in Pécs, Hungary, between 1 January 2016 and 15 October 2021. The mean age of the children was 6.2 years; 30.4% of them were younger than 1 year. An average of 3% total body surface was injured in the facial region and 47.8% of the patients had other areas damaged as well, most frequently the left upper limb (30.4%). The mean time until complete reepithelialization was 7.9 days and the children spent 2 days in the hospital. Wound cultures revealed normal bacterial growth in all cases and follow-up examinations found no hypertrophic scarring. In conclusion, pediatric facial superficial partial-thickness burns are prevalent during infancy and coincide with left upper limb injuries. Rapid wound closure and low complication rates are accountable for the moderate amount of hospitalization. These benefits, along with the gel’s ease of applicability and spontaneous separation, are linked to child-friendly burn care.
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- 2022
- Full Text
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