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36 results on '"Zoumpoulis, Pavlos"'

8. Assessment of biopsy‐proven liver fibrosis by two‐dimensional shear wave elastography: An individual patient data‐based meta‐analysis

Author

Herrmann, Eva, de Lédinghen, Victor, Cassinotto, Christophe, Chu, Winnie C.‐W., Leung, Vivian Y.‐F., Ferraioli, Giovanna, Filice, Carlo, Castera, Laurent, Vilgrain, Valérie, Ronot, Maxime, Dumortier, Jérôme, Guibal, Aymeric, Pol, Stanislas, Trebicka, Jonel, Jansen, Christian, Strassburg, Christian, Zheng, Rongqin, Zheng, Jian, Francque, Sven, Vanwolleghem, Thomas, Vonghia, Luisa, Manesis, Emanuel K., Zoumpoulis, Pavlos, Sporea, Ioan, Thiele, Maja, Krag, Aleksander, Cohen‐Bacrie, Claude, Criton, Aline, Gay, Joel, Deffieux, Thomas, and Friedrich‐Rust, Mireen

Published
2018
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9. Noninvasive, Blood-Based Biomarkers as Screening Tools for Hepatic Fibrosis in People With Type 2 Diabetes

Author

Meritsi, Angeliki, primary, Latsou, Dimitra, additional, Manesis, Emanuel, additional, Gatos, Ilias, additional, Theotokas, Ioannis, additional, Zoumpoulis, Pavlos, additional, Rapti, Stamatia, additional, Tsitsopoulos, Eustathios, additional, Moshoyianni, Hariklia, additional, Manolakopoulos, Spilios, additional, Pektasides, Dimitrios, additional, and Thanopoulou, Anastasia, additional

Published
2022
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11. Liver Ultrasound Attenuation

Author

Gatos, Ilias, primary, Drazinos, Petros, additional, Yarmenitis, Spyros, additional, Theotokas, Ioannis, additional, Koskinas, John, additional, Koullias, Emmanouil, additional, Mitranou, Asimina, additional, Manesis, Emmanuel, additional, and Zoumpoulis, Pavlos S., additional

Published
2022
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12. Speed of sound index for liver steatosis estimation: a reliability study in normal subjects.

Author

Gatos, Ilias, Drazinos, Petros, Loupas, Thanasis, Yarmenitis, Spyros, Koskinas, John, and Zoumpoulis, Pavlos S.

Subjects
ULTRASONIC imaging, RESEARCH evaluation, LIVER, SOCIAL networks, NON-alcoholic fatty liver disease, RESEARCH bias
Abstract

PURPOSE Non-alcoholic fatty liver disease (NAFLD) is the most widespread type of chronic liver disease in the Western countries. Ultrasound (US) is widely used for NAFLD staging. The Resona 7 US system (Mindray Bio-Medical Electronics Co., Ltd.) includes an image optimization and speed of ultrasound-related feature, Sound Speed Index (SSI). SSI is applied in a region of interest (ROI) that could potentially aid in tissue characterization. The purpose of this study is to evaluate the reliability of SSI on various examination parameters on normal subjects. METHODS Twenty normal subjects were examined by two radiologists performing SSI measurements in the liver in different ROI depths and sizes. Intraclass correlation coefficient (ICC) was calculated to measure intra- and inter-observer variability and inter-ROI variability. RESULTS For all ROIs and both radiologists, the mean inter-observer ICC was 0.62 and the mean intraobserver ICC was 0.52 and 0.79. The mean SSI values for all ROIs and examiners were in the range 1528.79-1540.16 m/s. CONCLUSION The results indicate that SSI can lead to reliable measurements on normal subjects, independent of ROI size but dependent on ROI placement. More studies processing NAFLD patients, utilizing reference methods of liver fat quantification either for reliability or correlation with SSI, should be performed to further investigate the relevance of the SSI as a potential biomarker in clinical practice for liver steatosis grading. [ABSTRACT FROM AUTHOR]

Published
2022
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13. Liver stiffness measurements by 2-dimensional shear wave elastography compared to histological and ultrasound parameters in primary biliary cholangitis

Author

Manesis, Emanuel K., primary, Schina, Maria, additional, Vafiadis, Irene, additional, Gatos, Ilias, additional, Theotokas, John, additional, Zoumpoulis, Pavlos, additional, Drazinos, Peter, additional, Ketikoglou, John, additional, Delladetsima, Ioanna K., additional, and Tiniakos, Dina G., additional

Published
2021
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16. A diagnostic approach of non-alcoholic fatty liver disease with a machine learning method using parameters derived from ultrasound B-mode examination

Author

Zoumpoulis, Pavlos

Subjects
Staging, genetic structures, Liver, Cirrhosis, Abdomen, Ultrasound, Statistics, FOS: Mathematics, Metabolic disorders
Abstract

Aims and objectives Methods and materials Results Conclusion Personal information References, Aims and objectives: Non-Alcoholic Fatty Liver Disease (NAFLD) is one the most widespread type of chronic liver disease in the Western Countries 1 . NAFLD may lead to Non- Alcoholic Steatohepatitis (NASH) and, if not opposed, to Cirrhosis and liver failure 1,2...

Published
2019
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17. Diagnostic Performance of Resona’s 7 Speed of Sound Index in B-Mode Ultrasound using Liver Biopsy as ‘Gold Standard’ for NAFLD and NASH assessment

Author

Zoumpoulis, Pavlos

Subjects
Staging, genetic structures, Liver, Cirrhosis, Abdomen, Ultrasound, Statistics, FOS: Mathematics, Metabolic disorders, Diagnostic procedure
Abstract

Aims and objectives Methods and materials Results Conclusion Personal information References, Aims and objectives: Non Alcoholic Fatty Liver Disease (NAFLD) is one the most widespread type of chronic liver disease in the Western Countries. 1 NAFLD may lead to Non Alcoholic Steatohepatitis (NASH) and, if not opposed, to Cirrhosis and liver failure. 1,2 Ultrasound...

Published
2019
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18. Assessment of biopsy-proven liver fibrosis by two-dimensional shear wave elastography: An individual patient data-based meta-analysis

Author

Herrmann, Eva de Ledinghen, Victor Cassinotto, Christophe and Chu, Winnie C. -W. Leung, Vivian Y. -F. Ferraioli, Giovanna and Filice, Carlo Castera, Laurent Vilgrain, Valerie Ronot, Maxime Dumortier, Jerome Guibal, Aymeric Pol, Stanislas and Trebicka, Jonel Jansen, Christian Strassburg, Christian and Zheng, Rongqin Zheng, Jian Francque, Sven Vanwolleghem, Thomas Vonghia, Luisa Manesis, Emanuel K. Zoumpoulis, Pavlos and Sporea, Ioan Thiele, Maja Krag, Aleksander Cohen-Bacrie, Claude Criton, Aline Gay, Joel Deffieux, Thomas and Friedrich-Rust, Mireen

Abstract

Two-dimensional shear wave elastography (2D-SWE) has proven to be efficient for the evaluation of liver fibrosis in small to moderate-sized clinical trials. We aimed at running a larger-scale meta-analysis of individual data. Centers which have worked with Aixplorer ultrasound equipment were contacted to share their data. Retrospective statistical analysis used direct and paired receiver operating characteristic and area under the receiver operating characteristic curve (AUROC) analyses, accounting for random effects. Data on both 2D-SWE and liver biopsy were available for 1,134 patients from 13 sites, as well as on successful transient elastography in 665 patients. Most patients had chronic hepatitis C (n=379), hepatitis B (n=400), or nonalcoholic fatty liver disease (n=156). AUROCs of 2D-SWE in patients with hepatitis C, hepatitis B, and nonalcoholic fatty liver disease were 86.3%, 90.6%, and 85.5% for diagnosing significant fibrosis and 92.9%, 95.5%, and 91.7% for diagnosing cirrhosis, respectively. The AUROC of 2D-SWE was 0.022-0.084 (95% confidence interval) larger than the AUROC of transient elastography for diagnosing significant fibrosis (P=0.001) and 0.003-0.034 for diagnosing cirrhosis (P=0.022) in all patients. This difference was strongest in hepatitis B patients. Conclusion: 2D-SWE has good to excellent performance for the noninvasive staging of liver fibrosis in patients with hepatitis B; further prospective studies are needed for head-to-head comparison between 2D-SWE and other imaging modalities to establish disease-specific appropriate cutoff points for assessment of fibrosis stage. (Hepatology 2018;67:260-272).

Published
2018

19. Shear Wave Sound Touch Elastography (STE) for Chronic Liver Disease (CLD): Guidelines and Case Studies

Author

Zoumpoulis, Pavlos

Subjects
genetic structures, Cirrhosis, Liver, education, Education and training, Ultrasound, Abdomen, Technology assessment, Technical aspects, Elastography, Spleen, Education
Abstract

Learning objectives Background Findings and procedure details Conclusion Personal information References, Learning objectives: An incorrect usage of Shear Wave technology, without properly following the updated Guidelines and not knowing the steps which characterize a specific solution, may lead the operator to a misleading analysis and a wrong diagnosis. This educational...

Published
2018
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22. Assessment of biopsy‐proven liver fibrosis by two‐dimensional shear wave elastography: An individual patient data‐based meta‐analysis

Author

Herrmann, Eva, primary, de Lédinghen, Victor, additional, Cassinotto, Christophe, additional, Chu, Winnie C.‐W., additional, Leung, Vivian Y.‐F., additional, Ferraioli, Giovanna, additional, Filice, Carlo, additional, Castera, Laurent, additional, Vilgrain, Valérie, additional, Ronot, Maxime, additional, Dumortier, Jérôme, additional, Guibal, Aymeric, additional, Pol, Stanislas, additional, Trebicka, Jonel, additional, Jansen, Christian, additional, Strassburg, Christian, additional, Zheng, Rongqin, additional, Zheng, Jian, additional, Francque, Sven, additional, Vanwolleghem, Thomas, additional, Vonghia, Luisa, additional, Manesis, Emanuel K., additional, Zoumpoulis, Pavlos, additional, Sporea, Ioan, additional, Thiele, Maja, additional, Krag, Aleksander, additional, Cohen‐Bacrie, Claude, additional, Criton, Aline, additional, Gay, Joel, additional, Deffieux, Thomas, additional, and Friedrich‐Rust, Mireen, additional

Published
2017
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23. Applying Broadband Dielectric Spectroscopy (BDS) for the Biophysical Characterization of Mammalian Tissues under a Variety of Cellular Stresses

Author

Souli, Maria, primary, Klonos, Panagiotis, additional, Fragopoulou, Adamantia, additional, Mavragani, Ifigeneia, additional, Pateras, Ioannis, additional, Kostomitsopoulos, Nikolaos, additional, Margaritis, Lukas, additional, Zoumpoulis, Pavlos, additional, Kaklamanis, Loukas, additional, Kletsas, Dimitris, additional, Gorgoulis, Vassilis, additional, Kyritsis, Apostolos, additional, Pissis, Polycarpos, additional, and Georgakilas, Alexandros, additional

Published
2017
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24. Detection and characterisation of prostate cancer using Shear Wave Elastography (SWE)

Author

Zoumpoulis, Pavlos

Subjects
genetic structures, Biopsy, Ultrasound physics, Elastography, Cancer
Abstract

Aims and objectives Methods and materials Results Conclusion Personal information References, Aims and objectives: Prostate Cancer (PRCA) is the most common malignancy in men in the western world [1]. Screening has a role to play in the detection of clinically important Prostate Cancer (PRCA) in asymptomatic patient, at an early stage, in order to apply a...

Published
2015
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25. Vibration - Controlled Transient Elastography (VCTE) and Shear Wave Elastography (SWE) for the diagnostic approach of chronic hepatitis and liver cirrhosis

Author

Zoumpoulis, Pavlos

Subjects
genetic structures, Liver, Cirrhosis, Statistics, Elastography
Abstract

Aims and objectives Methods and materials Results Conclusion Personal information References, Aims and objectives: The use of liver elastography has substantially developed in the past few years; the introduction of novel elastographic methods (Transient Elastography, point Shear Wave Elastography, Real Time Shear Wave Elastography, Strain Elastography) has...

Published
2015
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28. Trying different schemes in antibiotic prophylaxis of TRUS biopsy of the prostate results in minimizing infectious biopsy-related complications

Author

Zoumpoulis, Pavlos

Subjects
Biopsy, Ultrasound, Elastography, Urinary Tract / Bladder
Abstract

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: Prostate cancer is the most common cancer affecting men [1]. Its annual incidence has increased considerably in the last 10 years [2]. For a 50 year old man the lifetime risk of developing prostatic malignancy is as high as 42% [3]. Although the...

Published
2011
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36. Changes in Shear Wave Elastography after Lumacaftor/Ivacaftor Treatment in Children with Cystic Fibrosis.

Author

Kanavaki A, Kanavaki I, Zoumpoulis PS, Moustaki M, Douros K, and Loukou I

Subjects
Humans, Child, Cystic Fibrosis Transmembrane Conductance Regulator genetics, Mutation, Drug Combinations, Cystic Fibrosis diagnostic imaging, Cystic Fibrosis drug therapy, Cystic Fibrosis genetics, Elasticity Imaging Techniques
Abstract

Background: Lumacaftor/Ivacaftor (LUM/IVA) is an approved combination therapy for cystic fibrosis (CF) patients homozygous for F508del., Objective: This study aimed to detect changes in liver stiffness measurement (LSM) in patients under this treatment., Methods: The study population consisted of CF patients homozygous for F508del, 6 to 11 years old, who had been treated for six months with LUM/IVA. Shear wave elastography (SWE) was performed in all of them, before and 6 months after the commencement of treatment., Results: Thirty-one patients were included in the study. LSM values after treatment were significantly higher than the values before treatment (medians and interquartile ranges of LSM values before and after treatment: 5.6, 5.3-6.3 kPa and, 6.4, 6.0-7.6 kPa, respectively, p<0.001)., Conclusion: SWE can detect early changes in LSM in some CF patients treated with LUM/IVA., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Published
2023
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