25 results on '"Zoog, Stephen J."'
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2. Confirmatory detection of neutralizing antibodies to AAV gene therapy using a cell-based transduction inhibition assay
3. Ultra-sensitive AAV capsid detection by immunocapture-based qPCR following factor VIII gene transfer
4. Validation of an IFN-gamma ELISpot assay to measure cellular immune responses against viral antigens in non-human primates
5. Monitoring cell-mediated immune responses in AAV gene therapy clinical trials using a validated IFN-γ ELISpot method
6. Early Phase Clinical Immunogenicity of Valoctocogene Roxaparvovec, an AAV5-Mediated Gene Therapy for Hemophilia A
7. Activity of transgene-produced B-domain–deleted factor VIII in human plasma following AAV5 gene therapy
8. Depletion of interfering IgG and IgM is critical to determine the role of IgE in pegvaliase-associated hypersensitivity
9. Antibodies that neutralize cellular uptake of elosulfase alfa are not associated with reduced efficacy or pharmacodynamic effect in individuals with Morquio A syndrome
10. Ultra-sensitive AAV capsid detection by immunocapture-based qPCR following factor VIII gene transfer
11. Pharmacokinetic, pharmacodynamic, and immunogenic rationale for optimal dosing of pegvaliase, a PEGylated bacterial enzyme, in adult patients with phenylketonuria
12. Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo
13. Leveraging Image Cytometry for the Development of Clinically Feasible Biomarkers: Evaluation of Activated Caspase-3 in Fine Needle Aspirate Biopsies
14. Validation of an IFN-gamma ELISpot assay to measure cellular immune responses against viral antigens in non-human primates
15. Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition
16. Signaling and protein associations of a cell permeable CD40 complex in B cells
17. Molecular Characterization of CD40 Signaling Intermediates
18. Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials
19. Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
20. Caspase Inhibition by Baculovirus P35 Requires Interaction between the Reactive Site Loop and the β-Sheet Core
21. Chapter 12 - Leveraging Image Cytometry for the Development of Clinically Feasible Biomarkers: Evaluation of Activated Caspase-3 in Fine Needle Aspirate Biopsies
22. Measurement of conatumumab‐induced apoptotic activity in tumors by fine needle aspirate sampling
23. Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types
24. Antagonists of CD117 (cKit) signaling inhibit mast cell accumulation in healing skin wounds
25. Measurement of conatumumabinduced apoptotic activity in tumors by fine needle aspirate samplingThis study is based in part on a presentation given at the American Association of Pharmaceutical Scientists on June 21–24, 2009, Seattle, WA
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