1. Machine learning and robot-assisted synthesis of diverse gold nanorods via seedless approach
- Author
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Oyawale Adetunji Moses, Mukhtar Lawan Adam, Zijian Chen, Collins Izuchukwu Ezeh, Hao Huang, Zhuo Wang, Zixuan Wang, Boyuan Wang, Wentao Li, Chensu Wang, Zongyou Yin, Yang Lu, Xue-Feng Yu, and Haitao Zhao
- Subjects
Machine learning ,Robotic synthesis ,Nanomaterial synthesis ,Data-driven approach ,Chemistry ,QD1-999 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
The challenge of data-driven synthesis of advanced nanomaterials can be minimized by using machine learning algorithms to optimize synthesis parameters and expedite the innovation process. In this study, a high-throughput robotic platform was employed to synthesize over 1356 gold nanorods with varying aspect ratios via a seedless approach. The developed models guided us in synthesizing gold nanorods with customized morphology, resulting in highly repeatable morphological yield with quantifiable structure-modulating precursor adjustments. The study provides insight into the dynamic relationships between key structure-modulating precursors and the structural morphology of gold nanorods based on the expected aspect ratio. The high-throughput robotic platform-fabricated gold nanorods demonstrated precise aspect ratio control when spectrophotometrically investigated and further validated with the transmission electron microscopy characterization. These findings demonstrate the potential of high-throughput robot-assisted synthesis and machine learning in the synthesis optimization of gold nanorods and aided in the development of models that can aid such synthesis of as-desired gold nanorods.
- Published
- 2023
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