47 results on '"Ziyang Ye"'
Search Results
2. Research on an Assembly Building Buffer Zone Based on Gray Critical Chain
- Author
-
Jiaying Chen, Ziyang Ye, Zehui Ye, and Qiao Sun
- Subjects
assembled building ,OPA ,entropy weight method ,grey critical chain ,buffer size ,optimize construction period ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The complexity of construction in prefabricated buildings makes it vulnerable to uncertainty in project timelines, and traditional project timeline management is insufficient to control project timelines for prefabricated buildings. Therefore, research on project timeline management for prefabricated buildings is needed in order to optimize project timelines and improve project execution rates. This study proposed an improved method of setting prefabricated building buffer zones through the use of improved grey critical chain technology. Five major factors affecting project timelines in actual prefabricated construction projects were selected: personnel experience, degree of prefabrication, technical complexity, reasonableness of construction plans, and degree of construction space availability. The OPA technique was introduced and combined with the entropy weight method to improve the comprehensive weight coefficient of the grey critical chain calculation of the factors affecting the timeline. Other influencing coefficients were determined, and a new calculation method for the size of prefabricated building buffer zones was proposed. Monte Carlo simulations were conducted in Matlab on actual construction projects to ensure the scientific rationality of the improved method. The results showed that compared with the classical buffer calculation methods (cut-and-paste method, C&PM and square root standard deviation method, RSEM), the project timeline was reduced by 14.3% and 11.7%, respectively, using the improved method. The improved method not only reduces project uncertainties, but also achieves the goal of optimizing project timelines, and it is reasonable and effective. The results of the study provide a direction for the project timeline management of prefabricated building critical chains, and this method can be applied to the planning and management of prefabricated building buffer zones.
- Published
- 2023
- Full Text
- View/download PDF
3. Dynamic Response of a Single-Pier Jacking of a Continuous Box Girder Bridge Based on Vehicle–Bridge Coupling
- Author
-
Ziyang Ye, Changmin Yang, and Honggang Li
- Subjects
vehicle–bridge coupling ,continuous box girder bridge ,single-pier jacking ,impact factor ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
In order to improve the bearing capacity of a bridge under dynamic impact and at the same time to improve the durability and safety of the bridge, the bridge should be jacked up, and most of the current research on bridge jacking upgrading is on synchronous jacking upgrading. There has been little research on single-pier jacking upgrading, especially the dynamics response problem under single-pier jacking upgrading of the bridge. This paper is based on the principle of vehicle–bridge coupling, and the vehicle was analyzed at different speeds by using the established model, vehicle weight, and multi-lane driving, comparing the dynamic response of the bridge before and after the single-pier jacking retrofit. The study analyzed the impact of the bridge single-pier jacking retrofit on the bridge impact coefficient, and evaluated the impact coefficient of the bridge from the perspective of dynamics. A comprehensive evaluation of the bridge single-pier jacking retrofit project was carried out. The following conclusions are drawn: the single-pier jacking modification of the bridge increased the bridge’s capacity under dynamic impact and also enhanced the durability and safety of the bridge.
- Published
- 2023
- Full Text
- View/download PDF
4. Design—Construction Phase Safety Risk Analysis of Assembled Buildings
- Author
-
Ran Lv, Jiaying Chen, Qiao Sun, and Ziyang Ye
- Subjects
assembled building ,safety risk analysis ,porter diamond model ,structural equation model ,design-construction phase linkage ,Building construction ,TH1-9745 - Abstract
To reduce the impact of safety risks on assembled buildings, this paper explores the factors affecting the safety risks of constructed buildings from the perspective of linkage between the design and construction phases. The method identifies 10 first-level risk indicators and 25 s-level safety risk indicators in five dimensions of prefabricated components, personnel, management, environment, and technology in both the design and construction phases, utilizing literature induction, expert interviews, questionnaire surveys, and Porter’s diamond model. The structural equation model was used to quantify the weights of the 25 s-level safety risk indicators to highlight the safety risk analysis of the assembled building and avoid risk. The results of the study show that it is important to analyze the safety risk linkage between the design phase and construction phase of the assembled building; from the perspective of the design-construction phase linkage, controlling the safety risk in the design phase can effectively reduce the safety risk in the construction phase.
- Published
- 2023
- Full Text
- View/download PDF
5. Multi-sensor information fusion detection system for fire robot through back propagation neural network.
- Author
-
JunJie Zhang, ZiYang Ye, and KaiFeng Li
- Subjects
Medicine ,Science - Abstract
ObjectiveTo reduce the danger for firefighters and ensure the safety of firefighters as much as possible, based on the back propagation neural network (BPNN) the fire sensor multi-sensor information fusion detection system is investigated.MethodAccording to previous studies, the information sources and information processing methods for the design of this study are first explained. Then, the basic structure and flowchart of the research object in this study are designed. Based on the structure diagram and flowchart, the BPNN is selected to fuse the feature layers in this study, and the fuzzy control is selected to fuse the decision layers in this study. The multi-sensor information fusion detection system collects information for the sensors first, processes the collected information, and sends it to the processor of the robot. The processor analyzes and processes the received signal, and transmits the obtained information to the control terminal through the wireless communication system.ResultsThrough the tests in this study, it is found that when the number of hidden layer nodes of the BPNN is 7, the optimal training result is obtained. On this basis, the test of BPNN in this study is performed. The test results show that after 127 iterations, the error of the BPNN reaches the lowest target value, indicating that the BPNN achieves an excellent level of accuracy. The trained BPNN has a running time of 0.0276 s and a mean square error of 0.0013. The smaller the mean square error value is, the higher the accuracy of the BPNN is, which shows that the BPNN meets the high precision requirements of this study.ConclusionThe research on the multi-sensor information fusion detection system of fire robots in this study can provide theoretical support for the research on forest fire detection in China. Since the proposed BPNN-based robot is applied to the inspection and processing of forest remaining fire, the results are applicable to the forests of various countries, with a wide range of applications.
- Published
- 2020
- Full Text
- View/download PDF
6. Current Reconstruction and Sag/Wind Deflection Monitoring of Transmission Lines by Magnetic Sensing.
- Author
-
Yalong Mai, Yankai Xing, Ziyang Ye, Guangdou Zhang, and Jian Li 0056
- Published
- 2024
- Full Text
- View/download PDF
7. Dynamic Digital Circuit Locking (DDCL): A Shield against Static Analysis Attacks.
- Author
-
Ziyang Ye and Makoto Ikeda
- Published
- 2023
- Full Text
- View/download PDF
8. Practical Markov Chain and Von Neumann based Post-processing Circuits for True Random Number Generators.
- Author
-
Ruilin Zhang, Haochen Zhang, Xingyu Wang, Ziyang Ye, Kunyang Liu, and Hirofumi Shinohara
- Published
- 2023
- Full Text
- View/download PDF
9. Assessing the Vulnerability of Time-Controlled Logic-Loop-Based Circuits to Voltage Fault Injection and Power Monitoring Attacks.
- Author
-
Ziyang Ye and Makoto Ikeda
- Published
- 2023
- Full Text
- View/download PDF
10. Route recommendation method for frequent passengers in subway based on passenger preference ranking.
- Author
-
Xinyue Xu, Xiaoran Wang, Ziyang Ye, Anzhong Zhang, Jun Liu 0061, Linqi Xia, Zinuo Li, and Benxiang Feng
- Published
- 2024
- Full Text
- View/download PDF
11. Uncertainty-aware U-Net for Medical Landmark Detection.
- Author
-
Ziyang Ye, Haiyang Yu, and Bin Li 0015
- Published
- 2023
- Full Text
- View/download PDF
12. Optical super-resolution nanothermometry via stimulated emission depletion imaging of upconverting nanoparticles.
- Author
-
Ziyang Ye, Harrington, Benjamin, and Pickel, Andrea D.
- Subjects
- *
STIMULATED emission , *HIGH resolution imaging , *NANOPARTICLES , *HEAT transfer , *SPATIAL resolution , *OPTICAL resolution - Abstract
From engineering improved device performance to unraveling the breakdown of classical heat transfer laws, far-field optical temperature mapping with nanoscale spatial resolution would benefit diverse areas. However, these attributes are traditionally in opposition because conventional far-field optical temperature mapping techniques are inherently diffraction limited. Optical super-resolution imaging techniques revolutionized biological imaging, but such approaches have yet to be applied to thermometry. Here, we demonstrate a super-resolution nanothermometry technique based on highly doped upconverting nanoparticles (UCNPs) that enable stimulated emission depletion (STED) super-resolution imaging. We identify a ratiometric thermometry signal and maintain imaging resolution better than ~120 nm for the relevant spectral bands. We also form self-assembled UCNP monolayers and multilayers and implement a detection scheme with scan times >0.25 μm²/min. We further show that STED nanothermometry reveals a temperature gradient across a joule-heated microstructure that is undetectable with diffraction limited thermometry, indicating the potential of this technique to uncover local temperature variation in wide-ranging practical applications. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
13. Dynamic Digital Circuit Locking (DDCL): A Shield against Static Analysis Attacks
- Author
-
Ziyang, Ye, primary and Ikeda, Makoto, additional
- Published
- 2023
- Full Text
- View/download PDF
14. Assessing the Vulnerability of Time-Controlled Logic-Loop-Based Circuits to Voltage Fault Injection and Power Monitoring Attacks
- Author
-
Ziyang, Ye, primary and Ikeda, Makoto, additional
- Published
- 2023
- Full Text
- View/download PDF
15. Practical Markov Chain and Von Neumann based Post-processing Circuits for True Random Number Generators
- Author
-
Zhang, Ruilin, primary, Zhang, Haochen, additional, Wang, Xingyu, additional, Ziyang, Ye, additional, Liu, Kunyang, additional, and Shinohara, Hirofumi, additional
- Published
- 2023
- Full Text
- View/download PDF
16. Structural characterization and bioactivities of a novel polysaccharide obtained from Lachnum YM38 together with its zinc and selenium derivatives
- Author
-
Yaling He, Hui Chen, Ziyang Ye, Xinmiao Zhang, Hongling Ye, and Ming Ye
- Subjects
Bioengineering ,Applied Microbiology and Biotechnology ,Biochemistry - Published
- 2022
17. Technical Investigation on the Application of Ultrafiltration Membrane Process in the Upgrading and Reconstruction Project of Urban Sewage Plant
- Author
-
Sixu Fang, Bojun Xiao, Ziyang Ye, and Sichu Zhang
- Abstract
In recent years, for environmental quality requirements of our country continue to increase, the effluent quality of urban sewage treatment plants has improved correspondingly. A sewage treatment plants in Zhonglou District, Changzhou City originally used the traditional AAO treatment process, complying with the first level B standard of “Discharge standard of pollutants for municipal wastewater treatment plant”(GB18918-2002). However, according to the newest requirements of discharge standard, this sewage plant needs to be upgraded, improving to the first level a standard. The main measures include transforming the former treatment process into a two-stage A/O process (A-O-A-O), which focuses on nitrogen removal to strengthen the nitrogen removal capacity; adding a ultrafiltration membrane system to increase the removal rate of effluent SS and the refractory organic matter. After the completion of the upgrading project, the sewage treatment plant has been operating stably for 12 months. The effluent quality is stable and up to standards, meeting the design standards. This example of transformation can provide a technical reference for the transforming and upgrading projects of other sewage treatment plants, which share the same type of tight land use.
- Published
- 2022
18. Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway
- Author
-
Sunlong Li, Yifeng Shi, Shuhao Zhang, Haobin Li, Ziyang Ye, Jiangqian Kong, Weijun Hong, Yiting Tu, Jiaping Ren, Zaher Meftah, Chenglong Xie, Xiangyang Wang, and Xiaolei Zhang
- Subjects
Aging ,Article Subject ,Cell Biology ,General Medicine ,Biochemistry - Abstract
Purpose. OA is a multifactorial joint disease in which inflammation plays a substantial role in the destruction of joints. Corynoline (COR), a component of Corydalis bungeana Turcz., has anti-inflammatory effects. Materials and Methods. We evaluated the significance and potential mechanisms of COR in OA development. The viabilities of chondrocytic cells upon COR exposure were assessed by CCK-8 assays. Western blot, qPCR, and ELISA were used to assess extracellular matrix (ECM) degeneration and inflammation. The NF-κB pathway was evaluated by western blot and immunofluorescence (IF). Prediction of the interacting proteins of COR was done by molecular docking, while Nrf2 knockdown by siRNAs was performed to ascertain its significance. Micro-CT, H&E, Safranin O-Fast Green (S-O), toluidine blue staining, and immunohistochemical examination were conducted to assess the therapeutic effects of COR on OA in destabilization of medial meniscus (DMM) models. Results. COR inhibited ECM degeneration and proinflammatory factor levels and modulated the NF-κB pathway in IL-1β-treated chondrocytes. Mechanistically, COR bound Nrf2 to downregulate the NF-κB pathway. Moreover, COR ameliorated the OA process in DMM models. Conclusion. We suggest that COR ameliorates OA progress through the Nrf2/NF-κB axis, indicating COR may have a therapeutic potential for OA.
- Published
- 2022
19. Comparison of Overall Complication Rates in VCR-Based vs Non-VCR-Based Corrective Techniques in Severe Rigid Kyphoscoliosis Patients: A Systematic Review and Meta-Analysis
- Author
-
Nicholas Ishmael, Van Halm-Lutterodt, Neil Nazar, Al-Saidi, Krishna, Mandalia, Mohamed Kamal, Mesregah, Kristina Marie, Ghanem, Nicholas Robert, Storlie, Wei-Hsun, Huang, Wei-Cheng, Chen, Mercy, Bartels-Mensah, Xin Yuan, Chen, Ziyang, Ye, Yangpu, Zhang, Aixing, Pan, Sunny Sik, Kim, Baron, Lonner, Ahmet, Alanay, and Yong, Hai
- Subjects
Orthopedics and Sports Medicine ,Surgery ,Neurology (clinical) - Abstract
Study Design Systematic review and meta-analysis. Objective Compilation of complication outcomes data from the surgical management of severe rigid kyphoscoliosis patients using VCR-based vs non-VCR-based corrective maneuvers is lacking. This meta-analysis aimed to compare complication outcomes between those classified osteotomy approaches. Methods Thorough literature review and meta-analysis were conducted between January 2000 and September 2021. The selection criteria were studies: i) reporting major curve Cobb angle of ≥80° and flexibility of Results Of the 174 patients included, 52.30% (n = 91) and 47.70% (n = 83) were VCR-based and non-VCR-based, respectively. The incidence of dural tears/nerve injuries/significant intraoperative-neuromonitoring changes was significantly higher; [OR = 6.78, CI= (1.75 to 26.17), I2 = 0%, ( P = .006)] in the VCR-based group than the non-VCR-based group. The ‘overall surgical and medical’ complication rate was significantly higher in the VCR-based group, [OR = 1.94, CI= (1.02 to 3.67), I2 = 31%, ( P = .04)]. Conclusion Both VCR-based and non-VCR-based surgical techniques for management of severe rigid scoliosis and kyphoscoliosis patients pose comparable overall surgical complication rates, while a significantly higher perioperative neurological complication incidence was associated with VCR-based technique compared to the non-VCR-based techniques. The VCR-based technique was associated with 6.78 times higher incidence of neurological complications compared to non-VCR-based techniques.
- Published
- 2022
20. Performance study of vertical vibratory roller compaction of large thickness water stabilized layer
- Author
-
Changmin Yang, Honggang Li, Jinghui Pei, Bowen Qiao, Jianzhe Chu, Ziyang Ye, and Chaoyi Cui
- Published
- 2022
21. Gastroprotective effect of the Lachnum polysaccharide and polysaccharide-dipeptide conjugates against gastric ulcer
- Author
-
Xinmiao Zhang, Dong Liu, Ziyang Ye, Xue Chen, Hui Chen, and Ming Ye
- Subjects
General Medicine ,Toxicology ,Food Science - Published
- 2023
22. Lipid‐lowering effect of extracellular polyphenol extracts from Lachnum singerianum in high‐fat diet‐fed mice
- Author
-
Jing Ji, Dong Liu, Ziyang Ye, Wen Chen, Farnaz Shaikh, and Ming Ye
- Subjects
General Chemical Engineering ,General Chemistry ,Food Science - Published
- 2022
23. Ameliorate effects of soybean soluble polysaccharide on adenine-induced chronic renal failure in mice
- Author
-
Guohua Hou, Mingzhi Jin, Ming Ye, Qianli Huang, Ziyang Ye, and Xinmiao Zhang
- Subjects
Male ,medicine.medical_specialty ,Renal function ,02 engineering and technology ,SMAD ,Biochemistry ,Mice ,03 medical and health sciences ,chemistry.chemical_compound ,Polysaccharides ,Structural Biology ,In vivo ,Internal medicine ,medicine ,Animals ,Molecular Biology ,Blood urea nitrogen ,030304 developmental biology ,0303 health sciences ,Creatinine ,Kidney ,Adenine ,Albumin ,General Medicine ,021001 nanoscience & nanotechnology ,Endocrinology ,medicine.anatomical_structure ,chemistry ,Kidney Failure, Chronic ,Soybeans ,0210 nano-technology ,Transforming growth factor - Abstract
In the present study, the kidney protection effects of soluble soybean polysaccharide (SSPS) were evaluated. To address the issues, a mice model of Chronic renal failure (CRF) was established by gavage 0.2% (w/w) adenine for 3 weeks. In vivo results showed that SSPS could change the concentrations of blood urea nitrogen (BUN), creatinine (CRE), total protein (TP) and albumin (ALB), thereby affecting kidney function. In addition, Masson histopathology analysis indicated that SSPS could decrease the area of collagen fiber in the kidney tissues of CRF mice. Moreover, the results of mRNA expression and western experiment suggested that SSPS treatment could increase the expression of transforming growth factor-β (TGF-β), Smad3 and P-Smad3, while reduce the expression of α smooth muscle actin (α-SMA) when compared with the model group. These results indicated that SSPS potentially improve kidney function through TGF/Smad pathway in CRF mice.
- Published
- 2020
24. Lachnum polysaccharide suppresses S180 sarcoma by boosting anti-tumor immune responses and skewing tumor-associated macrophages toward M1 phenotype
- Author
-
Xinmiao Zhang, Xue Chen, Liu Yang, Shuai Zong, Ming Ye, Ziyang Ye, and Jinglei Li
- Subjects
Male ,medicine.medical_treatment ,02 engineering and technology ,Biology ,Biochemistry ,Mice ,03 medical and health sciences ,Immune system ,Ascomycota ,Cancer immunotherapy ,Structural Biology ,Immunity ,Cell Line, Tumor ,Tumor Microenvironment ,medicine ,Animals ,Humans ,Secretion ,Molecular Biology ,030304 developmental biology ,0303 health sciences ,Tumor microenvironment ,Macrophages ,Fungal Polysaccharides ,Sarcoma ,General Medicine ,Th1 Cells ,021001 nanoscience & nanotechnology ,Toll-Like Receptor 4 ,Phenotype ,RAW 264.7 Cells ,TLR4 ,Cancer research ,Signal transduction ,0210 nano-technology ,Reprogramming ,hormones, hormone substitutes, and hormone antagonists - Abstract
Therapeutic strategies that targeting tumor-associated macrophages (TAMs) reprogramming play a crucial role in ameliorating the immunosuppressive tumor microenvironment and boosting anti-tumor immune responses. In this study, we demonstrated that Lachnum polysaccharide (LEP) could work as an immunomodulator to reset TAMs from pro-tumor M2 to anti-tumor M1 phenotype. Mechanistically, LEP promoted Th1 polarization and the secretion of IFN-γ, which played a key role in M1 phenotype polarization. In parallel, LEP might directly activate M1 macrophages via TLR4 mediated NF-κB signaling pathway. Moreover, LEP also resulted in the accumulation of anti-tumor immune cells and decreased the infiltration of immunosuppressive cells such as myeloid-derived suppressor cells (MDSCs) and Treg cells, thereby potentiating anti-tumor immunity. In summary, these results revealed a novel mechanism of the anti-tumor effect of LEP and provided a potential new avenue targeting TAMs and cancer immunotherapy.
- Published
- 2020
25. Nonvolatile silicon photonic 1×2 switch by integrating the phase change chalcogenide into microring network
- Author
-
ZiYang Ye, Ruirui Song, and Shaolin Zhou
- Published
- 2021
26. Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF
- Author
-
Sunlong, Li, Yifeng, Shi, Shuhao, Zhang, Haobin, Li, Ziyang, Ye, Jiangqian, Kong, Weijun, Hong, Yiting, Tu, Jiaping, Ren, Zaher, Meftah, Chenglong, Xie, Xiangyang, Wang, and Xiaolei, Zhang
- Subjects
Inflammation ,Molecular Docking Simulation ,Chondrocytes ,NF-E2-Related Factor 2 ,Berberine Alkaloids ,Interleukin-1beta ,Osteoarthritis ,NF-kappa B ,Humans ,Cells, Cultured - Abstract
OA is a multifactorial joint disease in which inflammation plays a substantial role in the destruction of joints. Corynoline (COR), a component ofWe evaluated the significance and potential mechanisms of COR in OA development. The viabilities of chondrocytic cells upon COR exposure were assessed by CCK-8 assays. Western blot, qPCR, and ELISA were used to assess extracellular matrix (ECM) degeneration and inflammation. The NF-COR inhibited ECM degeneration and proinflammatory factor levels and modulated the NF-We suggest that COR ameliorates OA progress through the Nrf2/NF
- Published
- 2021
27. Laser heating with doughnut-shaped beams
- Author
-
Ziyang Ye, Chenhao Jian, and Andrea Pickel
- Subjects
General Physics and Astronomy - Abstract
Doughnut-shaped laser beams have applications in laser-based additive manufacturing, laser heating of diamond anvil cells, and optical super-resolution microscopy. In applications like additive manufacturing and heating of diamond anvil cells, a doughnut-shaped beam is frequently used to obtain a more uniform temperature profile relative to that generated by a conventional Gaussian beam. Conversely, in super-resolution microscopy, the doughnut-shaped beam serves to enhance spatial resolution and heating is an undesirable side effect that can cause thermal damage. Here, we develop analytical expressions for the temperature rise induced by a doughnut-shaped laser beam both alone and in combination with a Gaussian beam. For representative, experimentally determined beam radii and a wide range of thermal properties, we find that a doughnut-shaped beam results in a peak temperature rise no more than 90% and often less than 75% of that for a Gaussian beam with the same total power. Meanwhile, the region of the sample surface that reaches 80% of the maximum temperature rise is at least 1.5 times larger for a doughnut-shaped beam than for a Gaussian beam. When doughnut-shaped and Gaussian beams are applied simultaneously, the ratio of the maximum temperature rise for the two beams combined vs a Gaussian beam alone can be up to 2.5 times lower than the ratio of the doughnut-shaped vs the Gaussian beam power. For applications like super-resolution microscopy that require high doughnut-shaped laser beam powers, the doughnut-shaped beam intensity profile is thus advantageous for minimizing the total peak temperature rise when applied together with a Gaussian beam.
- Published
- 2022
28. Polysaccharides from Lachnum sp. Inhibited colitis-associated colon tumorigenesis in mice by modulating fecal microbiota and metabolites
- Author
-
Shuai Zong, Hongling Ye, Ziyang Ye, Yaling He, Xinmiao Zhang, and Ming Ye
- Subjects
Pharmacology ,Inflammation ,Bacteria ,Carcinogenesis ,Colon ,Immunology ,Dextran Sulfate ,Colitis ,Gastrointestinal Microbiome ,Mice, Inbred C57BL ,Disease Models, Animal ,Mice ,Polysaccharides ,Immunology and Allergy ,Animals - Abstract
It is still uncertain whether the consumption of Lachnum sp. polysaccharides (LEP) alleviates colorectal cancer (CRC) through the gut microbiota. In this study, our efforts are focused on the influence of LEP on CRC, intestinal barrier and inflammation, and fecal microbiota and the metabolites, in azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced CRC mice. Results showed that LEP inhibited CRC mouse colon shortening and weight loss, decreased tumor incidence, restored intestinal barrier integrity, and reduced excessive inflammation. LEP consumption significantly altered microbiota overall structure and community, with reduced pernicious bacteria (such as Parabacteroides, Escherichia_Shigella, Desulfovibrio and Helicobacter), and increased beneficial bacterium (such as Alistipes, Alloprevotella and Ruminiclostridium). Fecal-metabolome profile indicated that a total of 43 metabolites were clearly changed, with 10 down-regulated and 33 up-regulated metabolites. In addition, short-chain fatty acids (SCFAs), including acetic acid, propionic acid and n-butyric acid, were significantly increased after LEP administration. Moreover, a strong correlation between the fluctuant gut microbiota and metabolites was found. These findings provided not only deeper insights into the responsibility of LEP for CRC alleviation, and but also the potential of LEP as a promising candidate for CRC prevention and treatment.
- Published
- 2021
29. Study on temperature distribution of box-type distribution room under different load and ventilation conditions
- Author
-
Jiefu Zhang, Ziyang Ye, Peng Zhang, Ying Zhou, and Xianliang Zhang
- Subjects
Electric power system ,Power transmission ,law ,Ventilation (architecture) ,Empirical formula ,Environmental science ,Overheating (economics) ,Mechanics ,Transformer ,Switchgear ,law.invention ,Power (physics) - Abstract
As an important part of the power transmission and distribution network in the power system, many problems in the box-type distribution room deserve attention. Especially the overheating problem will seriously threaten the safe and stable operation of the devices in the power distribution room. To promote heat dissipation and ensure the normal operation of devices in the power distribution room, this paper established a three-dimensional thermal-flow field model for the box-type power distribution room based on the finite element principle. Through this simulation model, the temperature distribution of the box-type distribution room under different dry-type transformer load and ventilation conditions of the distribution room is studied. Besides, this paper found the relationship between the hot-spot temperature and load rate of the dry-type transformer and the inlet air velocity at the vent, and gave an empirical formula through the least-squares fitting method. Finally, it was found that when the inlet air velocity at the vent is set to 0.1m/s, the cost performance of heat dissipation is high. The research in this article is useful to guide the ventilation of the box-type distribution room and the operation of dry-type transformers.
- Published
- 2021
30. Effect of the addition of roselle ( Hibiscus sabdariffa L.) extracts on the rheological, textural, and antioxidant activity of fermented milks
- Author
-
Ming Ye, Jinglei Li, Guohua Hou, Liuqing Yang, Nana Su, and Ziyang Ye
- Subjects
Antioxidant ,ABTS ,Food industry ,business.industry ,DPPH ,medicine.medical_treatment ,Hibiscus sabdariffa ,010401 analytical chemistry ,Flavour ,food and beverages ,04 agricultural and veterinary sciences ,General Chemistry ,Total dissolved solids ,040401 food science ,01 natural sciences ,0104 chemical sciences ,chemistry.chemical_compound ,0404 agricultural biotechnology ,chemistry ,medicine ,Fermentation ,Food science ,business ,Food Science - Abstract
The study aims to evaluate the rheological, textural, and antioxidant activity of fermented milks with the addition of roselle (Hibiscus sabdariffa L.) extracts at concentrations of 0.0, 0.1, 0.2, and 0.3% (CFM, RFM₁, RFM₂, and RFM₃). The chemical composition of the fermented milks, including crude protein, fat, ash, total solids and non‐fat solids, were also determined. Gas chromatography–mass spectroscopy (GC‐MS) detected 42, 46, 47, and 49 kinds of volatile flavour compounds in CFM, RFM₁, RFM₂, and RFM₃, respectively. The antioxidant activity of fermented milks was measured using ferric reducing antioxidant power and scavenging capacities for 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) and 2,2’‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulphonic acid) (ABTS) radicals during 28 days of refrigerated storage. The results of this study are of great significance to improve the understanding and application of roselle extracts in the food industry. Both roselle and fermented milk are beneficial to human health, with many biological activities, such as antioxidant, hypoglycaemic, liver‐protecting, and antihypertensive properties; however, no attention has been paid to the combined effects of roselle and fermented milks. The study created a novel fermented milk and the results indicate that 0.3% roselle extracts can play the most important role in affecting the rheological, textural properties, and antioxidant activity of fermented milks, so this modification of fermented milk shows promise for potential application in the food industry.
- Published
- 2019
31. Protective effects of a Lachnum polysaccharide against liver and kidney injury induced by lead exposure in mice
- Author
-
Ming Ye, Xiaoming Gao, Maheen Mahwish Surhio, Ziyang Ye, Hongling Ye, Guohua Hou, and Jinglei Li
- Subjects
Male ,Antioxidant ,Biopsy ,medicine.medical_treatment ,education ,02 engineering and technology ,Pharmacology ,Kidney ,Kidney Function Tests ,Protective Agents ,Polysaccharide ,Biochemistry ,Antioxidants ,Mice ,03 medical and health sciences ,Nutraceutical ,Ascomycota ,Liver Function Tests ,Polysaccharides ,Structural Biology ,Lachnum ,Animals ,Medicine ,Molecular Biology ,030304 developmental biology ,chemistry.chemical_classification ,0303 health sciences ,biology ,business.industry ,Liver and kidney ,General Medicine ,021001 nanoscience & nanotechnology ,biology.organism_classification ,Lead Poisoning ,Disease Models, Animal ,Oxidative Stress ,medicine.anatomical_structure ,Liver ,chemistry ,Apoptosis ,Toxicity ,0210 nano-technology ,business ,Biomarkers ,hormones, hormone substitutes, and hormone antagonists - Abstract
This study was designed to investigate the liver and kidney protective efficacy of a Lachnum polysaccharide (LEP) against Pb-induced toxicity in mice. The results showed that LEP decreased the Pb-induced bodyweight loss and organ index. Moreover, biochemical analysis showed that treatment of LEP could improve antioxidant status (CAT, GSH-Px and MDA) and the injury of tissues (liver and kidney). In addition, the histopathological observations indicated that LEP could attenuate liver and kidney cell injury induced by Pb. For further studies, key proteins involved in hepatic and kidney apoptosis, including cleaved caspase-3, Bax, Bcl-2, TGF-β1 and α-SMA, were quantified. The present findings demonstrated that LEP is strongly effective in protecting against the liver and kidney injury induced by Pb. We hope this research can offer a theoretical base for development of polysaccharide based on nutraceutical food in future.
- Published
- 2019
32. Mechanism of bioactive polysaccharide from Lachnum sp. acts synergistically with 5‐fluorouracil against human hepatocellular carcinoma
- Author
-
Ming Ye, Qianli Huang, Ziyang Ye, Shuai Zong, Liu Yang, Jinglei Li, and Guohua Hou
- Subjects
0301 basic medicine ,MAPK/ERK pathway ,Cell cycle checkpoint ,Physiology ,education ,Clinical Biochemistry ,Cell ,03 medical and health sciences ,0302 clinical medicine ,Lachnum ,medicine ,Protein kinase B ,health care economics and organizations ,PI3K/AKT/mTOR pathway ,chemistry.chemical_classification ,Reactive oxygen species ,biology ,Cell Biology ,biology.organism_classification ,030104 developmental biology ,medicine.anatomical_structure ,chemistry ,030220 oncology & carcinogenesis ,Cancer research ,hormones, hormone substitutes, and hormone antagonists ,Intracellular - Abstract
The antimetabolite 5-fluorouracil (5-FU) is a widely used antitumor agent, however the overall response rate to 5-FU as a single agent is usually limited. Herein, how Lachnum expolysaccharide (LEP-2a), a type of active polysaccharide isolated from Lachnum sp., acted synergistically with 5-FU on HepG2 cells was investigated. It was found that LEP-2a notably enhanced 5-FU sensitivity in HepG2 cells in a synergistic manner. After combination treatment of 5-FU and LEP-2a, Ras/Raf/MEK/ERK and PI3K/AKT/mTOR pathway were inactivated. In addition, combination treatment induced generation of reactive oxygen species, decreased the levels of intracellular antioxidant enzymes and triggered mitochondrial apoptosis pathway. Furthermore, 5-FU combined with LEP-2a also resulted in p53 activation and NF-κB inhibition, and cell cycle arrest in the S phase as well as cell metastasis stagnation. Interestingly, LEP-2a treatment also blocked the DNA damage repair procedure. These findings demonstrate that LEP-2a enhanced 5-FU sensitivity and combination of 5-FU and LEP-2a exerts synergistic antitumor efficiency through multiple approaches.
- Published
- 2019
33. Structure, molecular modification and anti-tumor activity of melanin from Lachnum singerianum
- Author
-
Shuai Zong, Ming Ye, Jinglei Li, Ying Lu, Farnaz Shaikh, Ziyang Ye, and Liuqing Yang
- Subjects
0106 biological sciences ,0303 health sciences ,animal structures ,Chromatography ,Chemistry ,Lysine ,Infrared spectroscopy ,Bioengineering ,01 natural sciences ,Applied Microbiology and Biotechnology ,Biochemistry ,body regions ,03 medical and health sciences ,chemistry.chemical_compound ,Column chromatography ,Sephadex ,010608 biotechnology ,embryonic structures ,Proton NMR ,Molecular modification ,Molecule ,Histidine ,030304 developmental biology - Abstract
Intracellular melanin (LIM) was extracted from Lachnum singerianum YM296 mycelium. LIM-a, LIM-b and LIM-c were resolved from LIM by Sephadex G-15 column chromatography, in which LIM-a was the main homogeneous component with a molecular weight of 530 Da. Based on the elemental analysis, mass spectrometry, infrared spectroscopy and NMR analysis, the molecular formula (C28H20N2O7S2) and possible structural formula of LIM-a were proposed. In order to increase its water solubility, non-water-soluble LIM-a was modified by histidine, lysine and arginine, and histidine-melanin (HLIM-a) had the highest water solubility, being 47.7 mg mL−1 in distilled water at room temperature. Infrared spectroscopy, mass spectroscopy and 1H NMR analysis of HLIM-a indicated that histidine-melanin was formed by conjugating LIM-a molecule with histidine molecule. In vivo test showed that both LIM-a and HLIM-a had significant anti-tumor activity, in which HLIM-a showed better efficacy. Immunohistochemistry analysis and cytokines detection suggested that LIM-a and HLIM-a may repress tumor growth through activating the immune response.
- Published
- 2019
34. Antidiabetic effects of fermented milk contained with Gardenia jasminoides water extracts on streptozotocin‐induced mice
- Author
-
Ziyang Ye, Mingzhi Jin, Ming Ye, Xue Chen, and Yaling He
- Subjects
Traditional medicine ,biology ,Chemistry ,General Chemical Engineering ,medicine ,Fermentation ,General Chemistry ,Gardenia jasminoides ,Streptozotocin ,biology.organism_classification ,Food Science ,medicine.drug - Published
- 2021
35. Protective effect of Lachnum polysaccharide on dextran sulfate sodium-induced colitis in mice
- Author
-
Ming Ye, Xinmiao Zhang, Hui Chen, Shuai Zong, and Ziyang Ye
- Subjects
0301 basic medicine ,Male ,Colon ,medicine.medical_treatment ,education ,Nod ,Pharmacology ,Protective Agents ,Inflammatory bowel disease ,03 medical and health sciences ,Mice ,Random Allocation ,0302 clinical medicine ,Polysaccharides ,Lachnum ,medicine ,Animals ,Colitis ,Receptor ,Mice, Inbred ICR ,biology ,Chemistry ,Endoplasmic reticulum ,Dextran Sulfate ,Fungi ,Inflammasome ,General Medicine ,biology.organism_classification ,medicine.disease ,digestive system diseases ,Diet ,030104 developmental biology ,Cytokine ,030220 oncology & carcinogenesis ,Colitis, Ulcerative ,hormones, hormone substitutes, and hormone antagonists ,Food Science ,medicine.drug - Abstract
Inflammatory bowel disease (IBD) has been gradually considered as a public health challenge worldwide. This study determined the protective effect of Lachnum polysaccharide (LEP) on dextran sulfate sodium (DSS)-induced experimental colitis in mice and explored the underlying mechanism. Results showed that dietary LEP reduced DSS-induced disease activity index (DAI), colon shortening and colonic tissue damage. LEP treatment restored intestinal barrier integrity by regulating the expression of tight junction proteins and mucus layer protecting proteins. Moreover, pro-inflammatory cytokine production was inhibited by LEP through regulating PPARγ/NF-κB and IL-6/STAT3 pathways and inhibiting inflammatory cell infiltration. In addition, LEP also inhibited (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation, endoplasmic reticulum (ER) stress and oxidative/nitrosative stress induced by DSS. These results provided a scientific basis for LEP as a potential natural agent for protecting mice from DSS-induced IBD.
- Published
- 2020
36. An Online Monitoring System for Instrument Transformers in Power Systems Based on Wide-Area Synchronous Measurement
- Author
-
Hao Wang, Dake He, Liu Sujie, Zeng Lan, Bing Ai, Ziyang Ye, and Jiefu Zhang
- Subjects
Electric power system ,Reliability (semiconductor) ,Safe operation ,Wide area ,business.industry ,Computer science ,Big data ,Monitoring system ,Instrument transformer ,business ,Current transformer ,Reliability engineering - Abstract
In order to ensure the safe operation of power system and the accuracy and reliability of electric energy measurement, it is of great significance to develop a highly cost-effective on-line monitoring apparatus and evaluation system for the entire power grid. This paper proposed an online monitoring system for instrument transformers in power systems based on wide-area synchronous measurement, in which includes a number of operating equipment in power system, as well as their monitoring devices. The overall performance of various measurement equipment is evaluated using related analytical techniques based on big data technologies.
- Published
- 2019
37. An Application of Multistep Long-Short Term Memory Algorithm to Predict the Performance of Capacitor Voltage Transformer
- Author
-
Kun Liu, Yan Ping, Li Jinsong, Ziyang Ye, Dake He, and Qiang Shi
- Subjects
050101 languages & linguistics ,Neutral network ,Computer science ,05 social sciences ,Hardware_PERFORMANCEANDRELIABILITY ,02 engineering and technology ,Capacitance ,law.invention ,Capacitor ,Hardware_GENERAL ,law ,Outlier ,Capacitor voltage transformer ,Hardware_INTEGRATEDCIRCUITS ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,0501 psychology and cognitive sciences ,Dielectric loss ,Time series ,Transformer ,Algorithm - Abstract
This paper introduces how capacitor voltage transformers are monitored and concludes four key parameters of a capacitor voltage transformer, which are, ratio difference f U , phase error δ U , dielectric loss tanδ, and capacitance C. It then proposes a method with the Hampel filter to clean out the outliers of obtained parameters. Cleaned data are further stationarized and scaled to fit the requirements of a deep learning algorithm based on multistep Long-Short Term Memory neutral network, which analyzes the processed data to evaluate and predict the short-term operating performance of a capacitor voltage transformer.
- Published
- 2019
38. A Method to Predict the Trends of Operating Performance of Capacitive Voltage Transformers
- Author
-
Jiapeng Huang, Kun Liu, Dake He, Li Jinsong, Ziyang Ye, and Qiang Shi
- Subjects
Dual regression ,Time windows ,law ,Computer science ,Control theory ,Capacitive sensing ,Chronological time ,Regression analysis ,Transformer ,Regression ,Voltage ,law.invention - Abstract
In order to predict the trend of the operating performance of capacitive voltage transformers (CVTs), an innovative method, known as dual regression analysis algorithm, is proposed. Measured environmental parameters and CVT performance parameters are divided into groups chronologically. Each group of data set establishes one first-round regression equation between the environmental parameters and the performance parameters of a certain CVT. By extracting the coefficients of the first-round regression equations in different time windows and forming a set of vectors containing the environmental parameter coefficients, the second-round regression equation between the environmental parameter coefficients and the chronological time windows can be established, and thereby obtaining the CVT performance parameters, which are used to evaluate the operating performance and to predict the trend of the CVT operating performance. Real data are used to explain and verify the theory and the procedure.
- Published
- 2019
39. Quality properties, flavor and hypoglycemia activity of Kiwifruit-Bitter gourd fermented milks
- Author
-
Nana Su, Ming Ye, Tingting Chen, Ziyang Ye, and Jinglei Li
- Subjects
biology ,Syneresis ,Chemistry ,Bitter gourd ,Titratable acid ,04 agricultural and veterinary sciences ,Hypoglycemia ,biology.organism_classification ,medicine.disease ,040401 food science ,Biochemistry ,0404 agricultural biotechnology ,Lactobacillus ,medicine ,Gourd ,Fermentation ,Food science ,Flavor ,Food Science - Abstract
In this study, kiwifruit-bitter gourd juice was added to reconstituted milk at 5%, 10% and 15% (v/v) to prepare fermented milk (KBFM5, KBFM10 and KBFM15). Fermented milk without kiwifruit-bitter gourd juice was used as control fermented milk (CFM). Compared with CFM, the viable counts of Streptococcus thermophiles (St) in KBFM5, KBFM10 and KBFM15 were increased by 4.5%, 6.5% and 5.9%, Lactobacillus bulgaricus (Lb) were increased by 2.9%, 7.1% and 4.3%, and Bifidobacterium adolescentis (Ba) were increased by 9.0%, 11.5% and 10.7%, respectively. The value of initial titratable acidity (TA) of CFM was 82.4°T, the TA values of KBFM5, KBFM10 and KBFM15 were increased by 3.5%, 6.4% and 5.7%, respectively. Compared with CFM (water-holding capacity (WHC) was 79.69%; syneresis value was 324.3 g/kg), WHC of KBFM5, KBFM10 and KBFM15 were increased by 2.2%, 14.8% and 7.1%, and the syneresis values were reduced by 9.7%, 11.3% and 10.7%, respectively. The firmness value of CFM, KBFM5, KBFM10 and KBFM15 was 22.71, 26.84, 27.90, 23.56 g, the cohesiveness value was 126.92, 139.82, 153.56, 132.82 g/s, the consistency value was 13.38, 16.36, 18.38, 14.58 g, and the index of viscosity was 4.93, 7.56, 9.29, 6.16 g/s, respectively. KBFM10 has highest sensory scores (37.96-maximum 40) which was selected for investigation of volatile compounds and hypoglycemia activity. Thirty-six kinds of volatile compounds were identified in KBFM10 and thirty kinds in CFM, which were mainly aldehydes, alcohols, acids, ketones, and esters. During 28 day refrigerated storage, the values of α-glucosidase inhibition of CFM was 21.6%, 30.27%, 26.61%, 24.59%, 22.82%. The values α-glucosidase inhibition of KBFM10 was respectively increased by 28.61%, 34.13%, 38.67%, 36.07%, 37.77%. This study demonstrated that kiwifruit-bitter gourd juice can be added as an active ingredient in milk preparations to provide novel functional dairy products.
- Published
- 2018
40. Antitumor effects of melanin fromLachnumYM226 and its derivative in H22 tumor-bearing mice
- Author
-
Fang Shi, Ming Ye, Ziyang Ye, Liuqing Yang, Jinglei Li, Tingting Chen, and Xue Chen
- Subjects
0301 basic medicine ,Pharmacology ,biology ,Chemistry ,Angiogenesis ,fungi ,Organic Chemistry ,Basic fibroblast growth factor ,Pharmaceutical Science ,biology.organism_classification ,Biochemistry ,Vascular endothelial growth factor ,03 medical and health sciences ,chemistry.chemical_compound ,030104 developmental biology ,0302 clinical medicine ,In vivo ,030220 oncology & carcinogenesis ,Drug Discovery ,Lachnum ,Molecular Medicine ,Alkaline phosphatase ,Tumor necrosis factor alpha ,Blood urea nitrogen - Abstract
In the present study, we investigated the anti-tumor activities of the intracellular homogeneous melanin (LM) of Lachnum YM226 and its derivative (ALM) on liver cancer using murine H22 hepatocarcinoma model. The results showed that LM and ALM (50 and 200 mg kg-1) could effectively inhibit tumor growth of H22 tumour-bearing mice. The body weight, liver, spleen and thymus indices also improved in the LM and ALM treated groups. Moreover, the levels of alanine aminotransferase (ALT), aspartate aminotransaminase (AST), alkaline phosphatase (ALP), creatinine (CRE), blood urea nitrogen (BUN) and uric acid (UA) were lowered. Serum cytokines of interleukin-2 (IL-2), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) were increased on LM and ALM administration, while LM and ALM significantly decreased the vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) levels. The H&E staining indicated that LM and ALM exhibited antitumor activity in vivo by promoting apoptosis and inhibiting angiogenesis. The anti-tumor effect of ALM was more significant than that of LM for the same dose. In summary, the findings demonstrated that LM and ALM might be promising candidates for the prevention and treatment of HCC.
- Published
- 2018
41. Synergistic hepatoprotective effect of combined administration of Lachnum polysaccharide with silymarin
- Author
-
Qianli Huang, Ming Ye, Xinmiao Zhang, Wenqing Zhang, and Ziyang Ye
- Subjects
Antioxidant ,Combination therapy ,medicine.medical_treatment ,Clinical Biochemistry ,Pharmaceutical Science ,Apoptosis ,Inflammation ,Pharmacology ,Protective Agents ,medicine.disease_cause ,Polysaccharide ,01 natural sciences ,Biochemistry ,Structure-Activity Relationship ,chemistry.chemical_compound ,Ascomycota ,Polysaccharides ,Drug Discovery ,Lachnum ,medicine ,Humans ,Molecular Biology ,chemistry.chemical_classification ,Dose-Response Relationship, Drug ,Molecular Structure ,biology ,010405 organic chemistry ,Organic Chemistry ,Glutathione ,biology.organism_classification ,0104 chemical sciences ,010404 medicinal & biomolecular chemistry ,chemistry ,Hepatocytes ,Molecular Medicine ,medicine.symptom ,Oxidative stress ,Silymarin - Abstract
In recent years, combination therapy has gradually become one of the hot spots. As a new therapy strategy, we investigated the combination treatment of polysaccharide from Lachnum sp. (LEP-2b) with silymarin and compared the effects with mono-therapy. In this study, combining high-dose LEP-2b with silymarin (CH) significantly reduced serum biochemistry indexes (ALT, AST, AKP, LDH), hepatic inflammation (TNF-α, IL-6 and IL-1β) and improved the antioxidant status (SOD, CAT, GSH-Px, GSH, MDA and T-AOC), in which its effect on TNF-α was very significant (P 0.001). Therefore, the expressions of related proteins in the JNK/p38 signaling pathway associated with TNF-α were examined. The result showed that CH treatment markedly increased the expression of p-p38 and inhibited the JNK phosphorylation. TUNEL staining, immunohistochemical staining and western blot assays demonstrated that the hepatoprotective effect of CH treatment was probably related with inhibiting hepatocyte apoptosis. In summary, combination of high dose LEP-2b with silymarin would be a more effective method to protect liver injury than mono-therapy.
- Published
- 2021
42. Arc erosion behavior of Cu-Ti3SiC2 cathode and anode
- Author
-
Andi Wang, Peng Zhang, Ziyang Ye, and Tungwai Leo Ngai
- Subjects
010302 applied physics ,Materials science ,Metallurgy ,Composite number ,02 engineering and technology ,Vacuum arc ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Decomposition ,Cathode ,Surfaces, Coatings and Films ,Anode ,law.invention ,law ,Powder metallurgy ,0103 physical sciences ,Electrode ,Erosion ,0210 nano-technology ,Instrumentation - Abstract
Ti 3 SiC 2 and Cu-Ti 3 SiC 2 composite were prepared by means of powder metallurgy method and their arc erosion behaviors were investigated by SEM, XRD, EDS and micro-Raman spectroscopy. Erosion craters were formed after first vacuum breakdown; TiC x was detected as a decomposition product of Ti 3 SiC 2 electrodes and Cu-Ti 3 SiC 2 cathodes and anodes. It is found that Ti 3 SiC 2 particles are more vulnerable to vacuum arc erosion than Cu matrix in the Cu-Ti 3 SiC 2 composite. Most of the arc erosion focused on the Ti 3 SiC 2 particles during the breakdown. There are no erosion pits or craters formed on the Cu-Ti 3 SiC 2 anode surface, but significant amount of Mo that transferred from the Mo cathode was detected. Reaction between Mo and Ti 3 SiC 2 was also observed on the Cu-Ti 3 SiC 2 anode surface.
- Published
- 2017
43. Control Optimization Method of Substation Inspection Robot Based on Adaptive Visual Servo Algorithm
- Author
-
Ziyang Ye, Xiaoming Chen, Kaifeng Li, and Junjie Zhang
- Subjects
History ,Computer science ,Control (management) ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Robot ,Control engineering ,Servo ,Computer Science Applications ,Education - Abstract
In order to enhance the accuracy of the target image captured by the substation inspection robot, this paper proposes an AVS algorithm based control optimization method for the substation inspection robot, which uses the feature transformation method to match the image and template image of the substation equipment captured by the robot, verifies the existence status of the target image elements in the image, and calculates the offset pixel correction results to capture more Accurate target image. The experimental results show that the method effectively improves the efficiency of image capture of inspection robot in substation equipment, and has good practical performance.
- Published
- 2020
44. Structure and preventive effects against ethanol-induced gastric ulcer of an expolysaccharide from Lachnum sp
- Author
-
Hui-Ran Ye, Ming Ye, Ru-yue Yuan, Ping Xu, Ziyang Ye, and Liu Yang
- Subjects
Male ,Glycosylation ,education ,02 engineering and technology ,Methylation ,01 natural sciences ,Biochemistry ,Superoxide dismutase ,Sepharose ,Mice ,chemistry.chemical_compound ,Column chromatography ,Ascomycota ,Pepsin ,Structural Biology ,Gastric mucosa ,medicine ,Animals ,Monosaccharide ,Stomach Ulcer ,Molecular Biology ,health care economics and organizations ,chemistry.chemical_classification ,Ethanol ,biology ,010405 organic chemistry ,Monosaccharides ,Fungal Polysaccharides ,General Medicine ,Anti-Ulcer Agents ,021001 nanoscience & nanotechnology ,Malondialdehyde ,Molecular biology ,0104 chemical sciences ,Molecular Weight ,medicine.anatomical_structure ,chemistry ,Gastric Mucosa ,biology.protein ,Female ,0210 nano-technology ,hormones, hormone substitutes, and hormone antagonists - Abstract
An extracellular polysaccharide of Lachnum sp. (LEP) was purified by DEAE-cellulose 52 column chromatography and Sepharose CL-6B column chromatography. LEP-2a was identified to be a homogeneous component with an average molecular weight of 3.22 × 10(4)Da. The structure of LEP-2a was characterized by chemical and spectroscopic methods, including methylation analysis, periodate oxidation-smith degradation, infrared spectroscopy and NMR analysis. Results indicated that LEP-2a was a (1→3)-,(1→6)-β-D-Glcp, whose branch chain was consist of two d-glucopyranosyl residues linked by β-1,3-glycosidic linkage, which was linked at C6 of the backbone chain by β-1,6-glycosidic linkage. To study the protective effects of LEP-2a on the ethanol-induced gastric ulcer in mice, LEP-2a (100, 200 and 400mg/kg/d) was given to mice by gavage for 2 weeks. Results showed that LEP-2a significantly decreased the ulcer bleeding areas, pepsin activity, gastric juice volume, gastric juice total acidity and the malondialdehyde (MDA) content in serum. Meanwhile, the superoxide dismutase (SOD) increased significantly. The above findings suggested that LEP-2a had a significant preventive effect against the ethanol-induced gastric ulcer.
- Published
- 2016
45. Physicochemical properties, immunostimulatory activity of the Lachnum polysaccharide and polysaccharide-dipeptide conjugates
- Author
-
Xue Chen, Ming Ye, Ziyang Ye, Shuai Zong, Guohua Hou, and Jinglei Li
- Subjects
Polymers and Plastics ,education ,02 engineering and technology ,Viscoelastic Substances ,010402 general chemistry ,Polysaccharide ,01 natural sciences ,chemistry.chemical_compound ,Mice ,Differential scanning calorimetry ,Adjuvants, Immunologic ,Ascomycota ,Polysaccharides ,Materials Chemistry ,Lachnum ,Animals ,Thermal stability ,health care economics and organizations ,Cell Proliferation ,chemistry.chemical_classification ,Dipeptide ,Chromatography ,biology ,Chemistry ,Interleukin-6 ,Tumor Necrosis Factor-alpha ,Viscosity ,Macrophages ,High Energy Physics::Phenomenology ,Organic Chemistry ,Dipeptides ,021001 nanoscience & nanotechnology ,biology.organism_classification ,In vitro ,Elasticity ,0104 chemical sciences ,RAW 264.7 Cells ,Interleukin-2 ,High Energy Physics::Experiment ,Cytokine secretion ,0210 nano-technology ,hormones, hormone substitutes, and hormone antagonists ,Conjugate - Abstract
The physicochemical properties and the immunoregulatory actions in vitro of an exopolysaccharide from Lachnum (LEP) and its conjugation with a dipeptide (LEP-RH) were investigated aiming to improve their functional characteristics. The structure characteristic of the LEP and LEP-RH were determined via FT-IR and NMR. The physicochemical properties were evaluated by scanning electron microscopy (SEM), rheometer, and differential scanning calorimeter (DSC). SEM results showed that LEP-RH had a rough surface and relatively loose distribution that different from LEP. Rheological studies of LEP and LEP-RH at the same concentration indicated that LEP and LEP-RH have similar shear-thinning behaviors and gel-like structures, while LEP-RH has a better thermal stability than LEP. Bioassay results showed that treatment with the higher dosage (200 μg/mL) of LEP and LEP-RH stimulated the proliferation, cytokine secretion (IL-2, IL-6 and TNF-α) of RAW264.7 macrophages.
- Published
- 2018
46. Synergistic antitumor effect of polysaccharide from Lachnum sp. in combination with cyclophosphamide in hepatocellular carcinoma
- Author
-
Ming Ye, Qianli Huang, Jinglei Li, Liu Yang, Shuai Zong, Guohua Hou, and Ziyang Ye
- Subjects
0301 basic medicine ,Carcinoma, Hepatocellular ,Polymers and Plastics ,Combination therapy ,Cyclophosphamide ,Cell Survival ,medicine.medical_treatment ,education ,Antineoplastic Agents ,Apoptosis ,Mitochondrion ,Polysaccharide ,Fas ligand ,03 medical and health sciences ,Mice ,Immune system ,Ascomycota ,Cell Line, Tumor ,Materials Chemistry ,medicine ,Animals ,Humans ,chemistry.chemical_classification ,business.industry ,Organic Chemistry ,Liver Neoplasms ,Drug Synergism ,Fungal Polysaccharides ,medicine.disease ,Xenograft Model Antitumor Assays ,Mitochondria ,Gene Expression Regulation, Neoplastic ,030104 developmental biology ,chemistry ,Hepatocellular carcinoma ,Cancer research ,business ,Adjuvant ,hormones, hormone substitutes, and hormone antagonists ,medicine.drug - Abstract
Combination therapy with chemotherapeutics is attracting increasing attention as an important treatment option for hepatocellular carcinoma (HCC) due to its complex pathological characteristics. In this study, as a new therapy strategy, combination treatment of LEP-2a (a non-toxic polysaccharide from Lachnum sp.) with cyclophosphamide (CTX) was investigated. Results showed that combination treatment with LEP-2a and CTX processed a significantly synergistic anti-tumor effect in H22 tumor-bearing mice through Fas/FasL mediated caspase-dependent death pathway and mitochondria apoptosis pathway. Moreover, our study indicated that LEP-2a played a crucial role in enhancement of immune response, inhibition of tumor angiogenesis and down-regulation of survival associated proteins. Notably, side effects induced by CTX were relieved after LEP-2a treatment. These results support the conception that LEP-2a has the potential as an ideal adjuvant agent for a more effective combination therapy with CTX against HCC.
- Published
- 2018
47. The Design of Video Surveillance System Based on IEEE802.11n Protocol
- Author
-
Yuerun Wang, Qingliang Shao, and Ziyang Ye
- Subjects
Wireless router ,Computer science ,Video capture ,law ,business.industry ,Video tracking ,Real-time computing ,Video processing ,USB ,Chip ,business ,Computer hardware ,law.invention - Abstract
A design of system of video monitoring cars based on IEEE802.11n protocol. STM32 chip as the control core, image data gathered by free driver USB camera, was used to compression coding, which was sent to video receiver by the use of RT5350 wireless router module with WIFI. Then the user could send control command according to the situation to change the car running status to realize the spot real-time monitoring. The text showed that this system, with clear image acquisition, stable propagation effects and instant effective control, has a good application prospect.
- Published
- 2015
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.